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The Center for Structural Genomics of Infectious Diseases is a consortium of
laboratories using state-of-the-art structural biology methods to determine
the 3-D structures of proteins from
major human pathogens (see Overview for more detailed
information about our mission).
July 2010: The CSGID has determined its 200th protein structure.
The laboratories participating in the CSGID are:
Northwestern University
University of Chicago
J. Craig Venter Institute
University College London
University of Toronto
University of Virginia
UT Southwestern Medical Center at Dallas
Washington University School of Medicine
Targets: 5028
Targets requested by the community: 932
Targets with structures: 184
Structures: 225
Structures complexed with ligands: 57
Structures requested by the community: 50
Publications: 11

Title:
Crystal structure of pre-cleavage form of cysteine protease domain from Vibrio cholerae RtxA toxin
Authors:
Shuvalova, L., Minasov, G., Prochazkova, K., Satchell, K.J.F., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Clostridium difficile with Covalent Reaction Intermediate. Authors:
Minasov, G., Light, S.H., Shuvalova, L., Dubrovska, I., Winsor, J., Peterson, S.N., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID).
Title:
Structure of the type III effector/phosphothreonine lyase OspF from Shigella flexneriAuthors:
Singer A.U., Skarina T., Nocek B., Gordon R., Lam R., Kagan O., Edwards A.M., Joachimiak A., Chirgadze N.Y., Anderson W.F., Savchenko A., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Structure of a putative YscO homolog CT670 from Chlamydia trachomatisAuthors:
Lam, R., Singer, A., Skarina, T., Onopriyenko, O., Bochkarev, A., Brunzelle, J.S., Edwards, A.M., Anderson, W.F., Chirgadze, N.Y., Savchenko, A. 
Title:
2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252
Authors:
Halavaty, A.S., Minasov, G., Winsor, J., Dubrovska, I., Shuvalova, L., See, R., Zoraghi, R., Reiner, N., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.Authors:
Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Phosphopantetheine adenylyltransferase from Yersinia pestis.Authors:
Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuniAuthors:
Kim, Y., Zhou, M., Hasseman, J., Anderson, W.F., Joachimiak, A., CSGID.
Title:
Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein)
reductase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with NADP+Authors:
Hou, J., Chruszcz, M., Onopriyenko, O., Grimshaw, S., Porebski, P., Zheng, H., Savchenko, A., Anderson, W.,Minor, W. 
Title:
Crystal structure of transketolase in complex with thiamin diphosphate and calcium ionAuthors:
Nocek, B.,Makowska-Grzyska, M., Maltseva, N., Grimshaw, S., Joachimiak, A, Anderson, W., CSGID, NIAID, 
Title:
Crystal structure of transketolase in complex with thiamine diposphate, ribose-5-phosphate and calcium ionAuthors:
Nocek, B., Makowska-Grzyska, M., Maltseva, N., Grimshaw, S., Anderson, W., Joachimiak, A., CSGID
Title:
Crystal structure of transketolase in complex with thiamine diposphate, ribose-5-phosphate (pyranose form) and magnesium ionAuthors:
Nocek, B., Makowska-Grzyska, M., Maltseva, N., Grimshaw, S., Anderson, W., Joachimiak, A., CSGID
Title:
Crystal structure of acetylornithine aminotransferase (argD) from Campylobacter jejuniAuthors:
Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Skarina, T., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)

Title:
Crystal structure of tryptophanyl-tRNA synthetase from Yersinia pestis CO92Authors:
Nocek,B., Maltseva, N.,
Papazisi, L., Joachimiak, A. Anderson, W., CSGID,NIAID
Title:
2.25 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with thymidineAuthors:
Halavaty, A.S., Minasov, G., Shuvalova, L., Winsor, J., Dubrovska, I., Peterson, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Crystal Structure of Probable Cytoplasmic L-asparaginase from
Campylobacter jejuniAuthors:
Kim, Y., Makowska-Grzyska, M., Maltseva, N., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID
Title:
Crystal structure of serine hydroxymethyltransferase from Campylobacter jejuniAuthors:
Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Hasseman, J., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Crystal Structure of Dihydrodipicolinate Synthase from Campylobacter jejuniAuthors:
Kim, Y., Zhou, M., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID
Title:
Putative RNA methyltransferase from Yersinia pestis.Authors:
Osipiuk, J., Maltseva, N., Peterson, S., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Putative RNA methyltransferase from Yersinia pestis in complex with S-adenosyl-L-homocysteine.Authors:
Osipiuk, J., Maltseva, N., Peterson, S., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Crystal Structure of Pantoate-beta-Alanine Ligase from Salmonella typhimuriumAuthors:
Kim, Y., Makowska-Grzyska, M., Maltseva, N., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID
Title:
Crystal Structure of Pantoate-Beta-alanine Ligase from
Campylobacter jejuniAuthors:
Kim, Y., Zhou, M., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID
Title:
Crystal Structure of Phosphoserine Aminotransferase from Campylobacter jejuniAuthors:
Kim, Y., Gu, M., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID
Title:
Structural Flexibility in Region Involved in Dimer Formation of Nuclease Domain of Ribonuclase III (rnc) from Campylobacter jejuni.Authors:
Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
1.8 Angstrom Resolution Crystal Structure of Diaminopimelate Decarboxylase (lysA) from Vibrio cholerae.Authors:
Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
Crystal Structure of Nicotinate Phosphoribosyltransferasefrom Yersinia pestisAuthors:
Maltseva, N., Kim, Y., Gu, M., Anderson, W.F., Joachimiak, A., CSGID 
Title:
1.85 Angstrom Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2.Authors:
Minasov, G., Light, S.H., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Title:
1.03 Angstrom Crystal Structure of Q236A Mutant Type I Dehydroquinate Dehydratase (aroD) from Salmonella typhimuriumAuthors:
Light, S.H., Minasov, G., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN272200700058C.