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The Center for Structural Genomics of Infectious Diseases is a consortium of laboratories using state-of-the-art structural biology methods to determine the 3-D structures of proteins from major human pathogens (see Overview for more detailed information about our mission).

 February 2010: Protein determined by CSGID featured as the NIAID structure of the month.

November 2009: Protein determined by CSGID featured as the NIAID structure of the month.


August 13th, 2009: The CSGID has determined its 100th protein structure. For more information, read our press releases: (Northwestern University) (University of Virginia)

The laboratories participating in the CSGID are:

Northwestern University

University of Chicago

J. Craig Venter Institute

University College London

University of Toronto

University of Virginia

UT Southwestern Medical Center at Dallas

Washington University School of Medicine

Targets: 4138
Targets requested by the community: 815
Targets with structures: 129
Structures: 149
Structures complexed with ligands: 35
Structures requested by the community: 12
Publications: 6

Target IDP00167    community request
Title: Crystal structure of pre-cleavage form of cysteine protease domain from Vibrio cholerae RtxA toxin
Authors: Shuvalova, L., Minasov, G., Prochazkova, K., Satchell, K.J.F., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)





Target IDP90163    community request
Title: Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Clostridium difficile with Covalent Reaction Intermediate.
Authors: Minasov, G., Light, S.H., Shuvalova, L., Dubrovska, I., Winsor, J., Peterson, S.N., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID).





Target IDP90224    community request
Title: Structure of the type III effector/phosphothreonine lyase OspF from Shigella flexneri
Authors: Singer A.U., Skarina T., Nocek B., Gordon R., Lam R., Kagan O., Edwards A.M., Joachimiak A., Chirgadze N.Y., Anderson W.F., Savchenko A., Center for Structural Genomics of Infectious Diseases (CSGID)





Target IDP90225    community request
Title: Structure of a putative YscO homolog CT670 from Chlamydia trachomatis
Authors: Lam, R., Singer, A., Skarina, T., Onopriyenko, O., Bochkarev, A., Brunzelle, J.S., Edwards, A.M., Anderson, W.F., Chirgadze, N.Y., Savchenko, A.





Target IDP90258    community request
Title: 2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252
Authors: Halavaty, A.S., Minasov, G., Winsor, J., Dubrovska, I., Shuvalova, L., See, R., Zoraghi, R., Reiner, N., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)





Target IDP90525    community request
Title: 1.77 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961
Authors: Halavaty, A.S. Shuvalova, L. Minasov, G. Dubrovska, I. Winsor, J. Glass, E.M. Peterson, S.N. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)





Target IDP90549    community request
Title: Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.
Authors: Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)





Target IDP90549    community request
Title: Phosphopantetheine adenylyltransferase from Yersinia pestis.
Authors: Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)





Target IDP90564    community request
Title: Crystal structure of transketolase from Campylobacter jejuni subsp. jejuni NCTC 11168
Authors: Nocek B., Makowska-Grzyska M., Maltseva N., Grimshaw S., Anderson,W., Joachimiak, A.





Target IDP90711    community request
Title: Crystal Structure of Dihydrodipicolinate Synthase Campylobacter jejuni subsp. jejuni NCTC 11168
Authors: Kim, Y., Zhou, M., Hasseman, J., Anderson, W.F., Joachimiak, A. CSGID





Target IDP90922    community request
Title: 1.85 Angstrom Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2.
Authors: Minasov, G., Light, S.H., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)





Target IDP90922    community request
Title: Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 with Citrate Bound to the Active Site.
Authors: Minasov, G. Light, S.H. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)






Target IDP00044    100th structure
Title: Crystal structure of BA2930 in complex with CoA
Authors: Klimecka, M.M., Chruszcz, M., Skarina, T., Onopryienko, O., Cymborowski, M., Savchenko, A., Edwards, A., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)




This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN272200700058C.