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Organism Distribution: Pipeline

Organism Protein
targets		 Cloned
targets		 Expression
targets		 Soluble
targets		 Purified
targets		 Crystallized Diffraction Structures Deposits Efficiency *
Yersinia pestis CO92 755 750 495 348 200 55 46 46 46 6.1 %
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 495 484 381 297 183 56 44 44 44 9.1 %
Bacillus anthracis str. Ames 488 484 332 260 125 29 23 23 22 4.5 %
Vibrio cholerae O1 biovar El Tor str. N16961 453 452 368 299 171 51 39 38 38 8.4 %
Bacillus anthracis str. 'Ames Ancestor' 380 380 252 181 114 45 30 30 30 7.9 %
Campylobacter jejuni subsp. jejuni NCTC 11168 334 334 215 173 125 42 34 34 34 10.2 %
Francisella tularensis subsp. tularensis SCHU S4 313 311 203 160 103 38 27 27 27 8.7 %
Listeria monocytogenes EGD-e 278 269 122 111 51 12 11 11 11 4.1 %
Staphylococcus aureus subsp. aureus COL 267 260 197 158 114 26 20 19 19 7.3 %
Clostridium difficile 630 265 264 94 82 37 9 6 6 6 2.3 %
Coxiella burnetii RSA 493 195 195 129 44 13 6 4 4 4 2.1 %
Clostridium perfringens ATCC 13124 164 164 57 40 15 1 1 1 1 0.6 %
Bacillus anthracis str. Sterne 164 140 77 64 41 9 8 8 8 5.7 %
Toxoplasma gondii ME49 159 19 12 10 8 4 3 3 3 15.8 %
Vibrio vulnificus CMCP6 157 157 99 66 20 4 4 4 4 2.5 %
Chlamydia trachomatis D/UW-3/CX 140 140 70 32 22 3 3 3 3 2.1 %
Streptococcus pneumoniae str. Canada MDR_19A 111 0 0 0 0 0 0 0 0 0
Homo sapiens 67 0 0 0 0 0 0 0 0 0
Staphylococcus aureus subsp. aureus NCTC 8325 61 59 57 0 53 7 7 7 7 11.9 %
Yersinia pestis KIM 10 60 60 27 19 3 0 0 0 0 0
Vibrio parahaemolyticus RIMD 2210633 54 54 36 15 9 2 0 0 0 0
Escherichia coli O157:H7 str. Sakai 54 54 46 27 19 0 0 0 0 0
Monkeypox virus 50 50 33 20 5 0 0 0 0 0
Shigella flexneri 2a str. 2457T 38 38 28 23 14 5 2 2 2 5.3 %
Cowpox virus (Brighton Red) 37 37 15 6 3 0 0 0 0 0
Escherichia coli str. K-12 substr. MG1655 24 3 3 2 1 0 0 0 0 0
Shigella flexneri 23 5 4 4 4 0 0 0 0 0
Vibrio cholerae 22 22 16 13 13 1 1 1 1 4.5 %
Escherichia coli O157:H7 str. EDL933 19 19 13 10 3 0 0 0 0 0
Mycobacterium tuberculosis H37Rv 17 17 5 1 2 0 0 0 0 0
Enterococcus faecalis 17 12 11 11 11 3 1 1 1 8.3 %
Escherichia coli 042 16 16 12 6 3 0 0 0 0 0
Myxoma virus (strain Lausanne) 16 16 12 5 1 0 0 0 0 0
Escherichia coli CFT073 13 0 0 0 0 0 0 0 0 0
Toxoplasma gondii 13 3 2 1 1 0 0 0 0 0
Helicobacter pylori 26695 11 0 0 0 0 0 0 0 0 0
Staphylococcus aureus subsp. aureus MRSA252 11 11 9 4 7 1 1 1 1 9.1 %
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150 10 0 0 0 0 0 0 0 0 0
Escherichia coli 10 7 7 6 6 2 1 1 1 14.3 %
Staphylococcus aureus subsp. aureus Mu50 10 2 2 2 1 1 1 1 1 50 %
Enterococcus faecium 8 6 6 6 6 2 2 2 2 33.3 %
Shigella flexneri 2a str. 301 8 3 3 2 2 2 2 2 2 66.7 %
Bifidobacterium longum subsp. infantis ATCC 15697 7 7 5 3 2 1 1 1 1 14.3 %
Dengue virus 1 7 7 2 0 1 1 1 1 1 14.3 %
Escherichia coli UTI89 6 6 3 3 2 0 0 0 0 0
Pseudomonas aeruginosa 6 1 1 1 1 1 0 0 0 0
Staphylococcus aureus 6 1 1 1 1 0 0 0 0 0
Staphylococcus aureus subsp. aureus N315 6 4 3 0 0 0 0 0 0 0
Dengue virus 4 6 6 1 0 1 0 0 0 0 0
Bacteroides thetaiotaomicron VPI-5482 6 6 5 3 2 1 1 1 1 16.7 %
Listeria monocytogenes 5 4 3 1 3 1 1 1 1 25 %
Streptococcus pyogenes 5 0 0 0 0 0 0 0 0 0
synthetic construct 5 0 0 0 0 0 0 0 0 0
Dengue virus 3 5 4 1 1 0 0 0 0 0 0
Vaccinia virus WR 4 0 0 0 0 0 0 0 0 0
Francisella novicida U112 4 0 0 0 0 0 0 0 0 0
Enterococcus gallinarum 4 4 4 4 4 0 0 0 0 0
Acinetobacter baumannii 4 2 2 2 2 1 1 1 1 50 %
Streptococcus thermophilus LMD-9 4 0 0 0 0 0 0 0 0 0
Haemophilus influenzae PittII 3 3 1 1 0 0 0 0 0 0
Streptococcus equi subsp. zooepidemicus 3 0 0 0 0 0 0 0 0 0
Staphylococcus epidermidis RP62A 3 3 2 0 1 0 0 0 0 0
Shigella dysenteriae Sd197 3 0 0 0 0 0 0 0 0 0
Legionella pneumophila subsp. pneumophila str. Philadelphia 1 3 3 3 3 3 1 0 0 0 0
Dengue virus 2 3 3 2 0 0 0 0 0 0 0
Burkholderia mallei ATCC 23344 3 3 1 0 0 0 0 0 0 0
Streptococcus pneumoniae TIGR4 3 2 1 1 1 0 0 0 0 0
Chlamydia muridarum Nigg 3 0 0 0 0 0 0 0 0 0
Burkholderia pseudomallei MSHR346 3 0 0 0 0 0 0 0 0 0
Vibrio fischeri ES114 3 3 2 1 1 0 0 0 0 0
Chlamydia trachomatis 2 1 1 0 0 0 0 0 0 0
Streptococcus pneumoniae Hungary19A-6 2 0 0 0 0 0 0 0 0 0
Staphylococcus aureus subsp. aureus str. Newman 2 2 2 0 1 0 0 0 0 0
Pseudomonas aeruginosa PAO1 2 2 1 0 1 0 0 0 0 0
Bacillus subtilis subsp. subtilis str. 168 2 2 1 0 0 0 0 0 0 0
Human herpesvirus 8 2 0 0 0 0 0 0 0 0 0
Streptomyces griseus 2 2 2 2 2 0 0 0 0 0
Staphylococcus aureus subsp. aureus Mu3 2 2 0 0 0 0 0 0 0 0
Actinobacillus pleuropneumoniae serovar 5b str. L20 2 2 0 0 0 0 0 0 0 0
Streptococcus agalactiae A909 2 0 0 0 0 0 0 0 0 0
Yersinia pseudotuberculosis IP 32953 2 2 2 1 0 0 0 0 0 0
Acinetobacter baumannii ATCC 17978 2 2 2 0 1 1 1 1 1 50 %
Francisella tularensis subsp. holarctica LVS 2 0 0 0 0 0 0 0 0 0
Streptococcus pneumoniae str. Canada MDR_19F 2 0 0 0 0 0 0 0 0 0
Burkholderia pseudomallei K96243 2 2 1 1 0 0 0 0 0 0
Enterococcus faecium DO 2 0 0 0 0 0 0 0 0 0
Bacillus subtilis 2 0 0 0 0 0 0 0 0 0
Salmonella enterica subsp. enterica serovar Typhimurium 2 2 2 0 1 1 1 1 1 50 %
Streptococcus pyogenes NZ131 2 0 0 0 0 0 0 0 0 0
Vibrio parahaemolyticus 2 2 1 1 1 0 0 0 0 0
Toxoplasma gondii GT1 2 1 0 0 0 0 0 0 0 0
Streptococcus mutans UA159 2 0 0 0 0 0 0 0 0 0
Streptococcus sp. 'group G' 2 0 0 0 0 0 0 0 0 0
Streptococcus dysgalactiae subsp. equisimilis GGS_124 2 0 0 0 0 0 0 0 0 0
Streptococcus pyogenes M1 GAS 1 0 0 0 0 0 0 0 0 0
Proteus mirabilis 1 0 0 0 0 0 0 0 0 0
Cowpox virus 1 1 1 0 1 1 0 0 0 0
SARS coronavirus 1 0 0 0 0 0 0 0 0 0
Streptococcus dysgalactiae subsp. equisimilis 1 0 0 0 0 0 0 0 0 0
Acinetobacter baumannii SDF 1 0 0 0 0 0 0 0 0 0
Zaire ebolavirus 1 0 0 0 0 0 0 0 0 0
Streptococcus pyogenes str. Manfredo 1 0 0 0 0 0 0 0 0 0
Enterococcus faecalis V583 1 1 1 1 1 0 0 0 0 0
Shigella dysenteriae 1012 1 0 0 0 0 0 0 0 0 0
Modoc virus 1 1 1 0 1 0 0 0 0 0
Influenza B virus (B/Lee/40) 1 1 1 1 1 0 0 0 0 0
Vaccinia virus Copenhagen 1 0 0 0 0 0 0 0 0 0
Neisseria gonorrhoeae FA 1090 1 1 0 0 0 0 0 0 0 0
Acinetobacter sp. ATCC 27244 1 0 0 0 0 0 0 0 0 0
Streptococcus suis P1/7 1 0 0 0 0 0 0 0 0 0
Streptococcus gallolyticus UCN34 1 0 0 0 0 0 0 0 0 0
Pseudomonas fluorescens Pf-5 1 1 0 0 0 0 0 0 0 0
Treponema pallidum subsp. pallidum str. Nichols 1 1 1 0 1 0 0 0 0 0
Streptococcus thermophilus LMG 18311 1 0 0 0 0 0 0 0 0 0
Streptococcus pneumoniae G54 1 0 0 0 0 0 0 0 0 0
Ectromelia virus 1 1 1 0 1 1 1 1 1 100 %
Streptococcus agalactiae 2603V/R 1 0 0 0 0 0 0 0 0 0
Streptococcus infantarius subsp. infantarius ATCC BAA-102 1 0 0 0 0 0 0 0 0 0
Staphylococcus epidermidis 1 1 1 1 1 0 0 0 0 0
Influenza A virus (A/udorn/1972(H3N2)) 1 1 0 0 0 0 0 0 0 0
Western equine encephalomyelitis virus 1 1 0 0 0 0 0 0 0 0
Streptococcus parauberis KCTC 11537 1 0 0 0 0 0 0 0 0 0
St. Louis encephalitis virus (strain MS1-7) 1 1 1 0 1 0 0 0 0 0
Influenza A virus (A/Aichi/2/1968(H3N2)) 1 0 0 0 0 0 0 0 0 0
Streptococcus agalactiae NEM316 1 0 0 0 0 0 0 0 0 0
Influenza A virus (A/California/07/2009(H1N1)) 1 1 1 1 1 1 1 1 1 100 %
Streptococcus suis SC84 1 0 0 0 0 0 0 0 0 0
Human herpesvirus 6 1 1 0 0 0 0 0 0 0 0
Helicobacter pylori J99 1 1 0 0 0 0 0 0 0 0
Streptococcus downei F0415 1 0 0 0 0 0 0 0 0 0
Agrobacterium tumefaciens str. C58 1 0 0 0 0 0 0 0 0 0
Murid herpesvirus 4 1 0 0 0 0 0 0 0 0 0
Streptomyces fradiae 1 1 1 1 1 0 0 0 0 0
Vibrio mimicus 1 0 0 0 0 0 0 0 0 0
Vaccinia virus 1 0 0 0 0 0 0 0 0 0
Streptococcus equi subsp. zooepidemicus MGCS10565 1 0 0 0 0 0 0 0 0 0
Pseudomonas putida KT2440 1 1 0 0 0 0 0 0 0 0
Montana myotis leukoencephalitis virus 1 1 1 0 1 0 0 0 0 0
Streptococcus equinus ATCC 9812 1 0 0 0 0 0 0 0 0 0
Murray Valley encephalitis virus 1 1 0 0 0 0 0 0 0 0
Staphylococcus aureus subsp. aureus USA300_TCH1516 1 1 0 0 0 0 0 0 0 0
Streptococcus pneumoniae TCH8431/19A 1 0 0 0 0 0 0 0 0 0
Escherichia coli O103:H2 str. 12009 1 0 0 0 0 0 0 0 0 0
Legionella pneumophila 130b 1 1 1 1 1 0 0 0 0 0
Vibrio sp. AND4 1 0 0 0 0 0 0 0 0 0
Enterobacter cloacae 1 0 0 0 0 0 0 0 0 0
Japanese encephalitis virus 1 1 1 0 1 1 1 1 1 100 %
Streptococcus uberis 0140J 1 0 0 0 0 0 0 0 0 0
Yellow fever virus 1 1 1 0 1 0 0 0 0 0
Rio Bravo virus 1 1 1 0 0 0 0 0 0 0
Streptococcus porcinus str. Jelinkova 176 1 0 0 0 0 0 0 0 0 0
Vibrio cholerae O395 1 1 1 0 0 0 0 0 0 0
Human echovirus 7 1 0 0 0 0 0 0 0 0 0
Streptomyces toyocaensis 1 0 0 0 0 0 0 0 0 0
Helicobacter pylori 1 0 0 0 0 0 0 0 0 0
Streptococcus pyogenes MGAS5005 1 1 0 0 0 0 0 0 0 0
Herpesvirus saimiri (strain 488) 1 0 0 0 0 0 0 0 0 0
Providencia stuartii 1 1 1 0 0 0 0 0 0 0
Vaccinia virus L-IPV 1 0 0 0 0 0 0 0 0 0
Streptococcus bovis ATCC 700338 1 0 0 0 0 0 0 0 0 0
Bordetella pertussis Tohama I 1 1 0 0 0 0 0 0 0 0
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) 1 0 0 0 0 0 0 0 0 0
Coxsackievirus B3 (strain Woodruff) 1 0 0 0 0 0 0 0 0 0
Escherichia coli ETEC H10407 1 1 0 0 0 0 0 0 0 0
Acinetobacter haemolyticus 1 0 0 0 0 0 0 0 0 0
Borrelia burgdorferi B31 1 0 0 0 0 0 0 0 0 0
Rickettsia prowazekii str. Madrid E 1 1 0 0 0 0 0 0 0 0
Streptococcus pneumoniae R6 1 0 0 0 0 0 0 0 0 0
Human herpesvirus 8 type M 1 0 0 0 0 0 0 0 0 0
Cell fusing agent virus 1 1 0 0 0 0 0 0 0 0
Aquifex aeolicus VF5 1 1 0 0 0 0 0 0 0 0
Staphylococcus haemolyticus 1 1 1 1 1 1 0 0 0 0
Mycobacterium smegmatis str. MC2 155 1 1 0 0 0 0 0 0 0 0
Pseudomonas aeruginosa UCBPP-PA14 1 1 1 1 1 0 0 0 0 0
Mus musculus 1 0 0 0 0 0 0 0 0 0
Streptococcus pneumoniae P1031 1 0 0 0 0 0 0 0 0 0

* Percentage of deposits per clone

  • Summary
  • Organism Distribution: Targets and Structures
  • Organism Distribution: Pipeline
  • Structures Statistics
  • Comparison with Other SG Centers
  • Ligands in Deposits
  • Infectious Pathogens
  • Homologs in PDB