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Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
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1
6
8
Keyword:
Type Keyword
Stage:
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cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
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CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP91735
(
show subtarget assignments
)
8
selected
Q4W8J9_STAAU
0
663
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2A1D
29.9%
Staphylococcus aureus
IDP91752
(
show subtarget assignments
)
8
selected
TIP_SHV2C
0
256
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
Herpesvirus saimiri
IDP91684
(
show subtarget assignments
)
8
selected
NCAP_CVHSA
0
422
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1SSK
32.9%
SARS coronavirus
IDP91742
(
show subtarget assignments
)
8
selected
Q6V4L9_STRPY
0
391
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2TMA
18.4%
Streptococcus pyogenes
IDP91669
(
show subtarget assignments
)
8
selected
AGSK1_HUMAN
0
129
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
Homo sapiens
IDP91660
(
show subtarget assignments
)
8
selected
LAMA5_HUMAN
0
3695
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2Y38
9.6%
Homo sapiens
IDP91670
(
show subtarget assignments
)
8
selected
ANTR2_HUMAN
0
489
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1SHU
37%
Homo sapiens
IDP91683
(
show subtarget assignments
)
8
selected
MYC_HUMAN
0
439
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1NKP
18.9%
Homo sapiens
IDP91671
(
show subtarget assignments
)
8
selected
VK03_VACCC
0
88
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1LUZ
98.9%
Vaccinia virus
IDP91672
(
show subtarget assignments
)
8
selected
ARP4_STRPY
0
386
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1I84
19.7%
Streptococcus pyogenes
IDP91745
(
show subtarget assignments
)
8
selected
Q846V4_STAAU
0
660
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2A1D
45.6%
Staphylococcus aureus
IDP91675
(
show subtarget assignments
)
8
selected
CREB3_HUMAN
0
395
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
Homo sapiens
IDP91737
(
show subtarget assignments
)
8
selected
Q5WMC9_ECOLX
0
550
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1F02
11.1%
Escherichia coli
IDP91681
(
show subtarget assignments
)
8
selected
LAMC3_HUMAN
0
1587
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2Y38
8.9%
Homo sapiens
IDP91674
(
show subtarget assignments
)
8
selected
CGA1_HELPY
0
1147
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3IEC
6.9%
Helicobacter pylori
IDP91736
(
show subtarget assignments
)
8
selected
Q51451_PSEAE
0
453
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1R4T
30.7%
Pseudomonas aeruginosa
IDP91746
(
show subtarget assignments
)
8
selected
Q8BDF8_9POXV
0
500
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
Vaccinia virus
IDP91673
(
show subtarget assignments
)
8
selected
CD44_HUMAN
0
742
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1POZ
21.4%
Homo sapiens
IDP91668
(
show subtarget assignments
)
8
selected
Q914E0_9ENTO
0
2194
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2IJD
20.6%
Human echovirus
IDP91244
(
show subtarget assignments
)
8
selected
HP0663
0
365
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1UM0
100%
Helicobacter pylori
Amino acid biosynthesis: Aromatic amino acid family
IDP91053
(
show subtarget assignments
)
8
selected
ENC0002
0
247
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3B89
42.1%
Enterobacter cloacae
IDP91089
(
show subtarget assignments
)
8
cloned
NT06FT0892
0
323
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
31.9%
Francisella tularensis
Energy metabolism: Sugars
IDP91240
(
show subtarget assignments
)
8
selected
HP1280
0
335
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1KGZ
39.4%
Helicobacter pylori
Amino acid biosynthesis: Aromatic amino acid family
IDP91734
(
show subtarget assignments
)
8
selected
PTN11_HUMAN
0
593
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2SHP
88%
Homo sapiens
IDP91739
(
show subtarget assignments
)
8
selected
Q6V4K9_STRPY
0
310
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2XNX
17.1%
Streptococcus pyogenes
IDP91744
(
show subtarget assignments
)
8
selected
Q76ZW2_VACCW
0
190
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1OYI
39.5%
Vaccinia virus
IDP91753
(
show subtarget assignments
)
8
selected
TSST_STAAU
0
234
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2IJ0
82.5%
Staphylococcus aureus
IDP91756
(
show subtarget assignments
)
8
selected
VF01_VACCP
0
206
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2VTY
81.1%
Vaccinia virus
IDP91738
(
show subtarget assignments
)
8
selected
Q5YB85_STRSG
0
598
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1I84
15.1%
Streptococcus sp.
IDP91678
(
show subtarget assignments
)
8
selected
H5_VACCW
0
203
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
Vaccinia virus
IDP91757
(
show subtarget assignments
)
8
selected
VF01_VACCW
0
226
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2VTY
73%
Vaccinia virus
IDP91754
(
show subtarget assignments
)
8
selected
TVB1_HUMAN
0
116
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3UTP
80.2%
Homo sapiens
IDP91680
(
show subtarget assignments
)
8
selected
INLB_LISMO
0
630
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1M9S
93.7%
Listeria monocytogenes
IDP91676
(
show subtarget assignments
)
8
selected
DNJA3_HUMAN
0
480
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3LZ8
19.6%
Homo sapiens
IDP91740
(
show subtarget assignments
)
8
selected
Q6V4L1_STRPY
0
398
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2XNX
14.6%
Streptococcus pyogenes
IDP91750
(
show subtarget assignments
)
8
selected
SPG2_STRSG
0
593
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2KN4
12.1%
Streptococcus sp.
IDP91751
(
show subtarget assignments
)
8
selected
STRP_STREQ
0
440
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1BML
81.1%
Streptococcus dysgalactiae
IDP91741
(
show subtarget assignments
)
8
selected
Q6V4L4_STRPY
0
397
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1I84
22.4%
Streptococcus pyogenes
IDP91667
(
show subtarget assignments
)
8
selected
POLG_CXB3W
0
2185
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2IJD
20.7%
Coxsackievirus B3
IDP91732
(
show subtarget assignments
)
8
selected
O67990_VIBMI
0
628
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2Y3U
16.6%
Vibrio mimicus
IDP91748
(
show subtarget assignments
)
8
selected
Q933J5_PSEAE
0
453
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1R4T
30.5%
Pseudomonas aeruginosa
IDP91758
(
show subtarget assignments
)
8
selected
VWF_HUMAN
0
2813
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1SQ0
7.5%
Homo sapiens
IDP91733
(
show subtarget assignments
)
8
selected
P88946_HHV8
0
449
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2DLL
6.9%
Human herpesvirus
IDP91743
(
show subtarget assignments
)
8
selected
Q76ZN6_VACCW
0
219
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2VGA
90.9%
Vaccinia virus
IDP91755
(
show subtarget assignments
)
8
selected
TXD11_HUMAN
0
958
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2B5E
7%
Homo sapiens
IDP91666
(
show subtarget assignments
)
8
selected
NS1_I68A0
0
237
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3F5T
77.2%
Influenza A
IDP91749
(
show subtarget assignments
)
8
selected
Q9DUM3_HHV8
0
1036
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3H0G
9.3%
Human herpesvirus
IDP91747
(
show subtarget assignments
)
8
selected
Q8WLQ7_HUMAN
0
79
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1D5M
94.9%
Homo sapiens
IDP91870
(
show subtarget assignments
)
8
selected
CAA30578
38663
unnamed protein product [Acinetobacter b...
259
drug resistance /
confers resistance to aminoglycoside antibiotics by phosphorylation
Community Requests
2BKK
34.4%
Acinetobacter baumannii
IDP91534
(
show subtarget assignments
)
8
selected
CAA36299
40706
major outer membrane protein precursor [...
395
vaccine candidate /
Vaccine formulation
Community Requests
Chlamydia trachomatis
IDP91188
(
show subtarget assignments
)
1
in_pdb
3TYK
CAA24743
40923
unnamed protein product [Escherichia col...
341
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3OVC
100%
Escherichia coli
IDP91797
(
show subtarget assignments
)
8
purified
CAA23892
43749
neomycin phosphotransferase [Escherichia...
264
other biological interest /
Kinase
Community Requests
1ND4
100%
Escherichia coli
IDP91782
(
show subtarget assignments
)
8
purified
CAA38136
46982
fosB
fosB [Staphylococcus epidermidis]
139
drug resistance /
Fosfomycin resistance
Community Requests
3UH9
59.7%
Staphylococcus epidermidis
IDP91795
(
show subtarget assignments
)
8
purified
CAA24789
47034
unnamed protein product [Enterococcus fa...
264
other biological interest /
Kinase
Community Requests
1J7I
100%
Enterococcus faecalis
IDP91186
(
show subtarget assignments
)
1
purified
CAA37605
47078
unnamed protein product [Streptomyces gr...
272
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1ND4
39.8%
Streptomyces griseus
IDP91780
(
show subtarget assignments
)
8
cloned
CAA27977
48190
unnamed protein product [Enterococcus fa...
639
drug resistance /
Tetracycline resistance
Community Requests
1DAR
28.4%
Enterococcus faecalis
IDP00252
(
show subtarget assignments
)
1
purified
130516
St. Louis encephalitis virus Envelope pr...
407
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
2I69
70.5%
St. Louis
IDP91787
(
show subtarget assignments
)
8
purified
AAA24786
148325
vanC
D-alanine-D-alanine ligase-related prote...
343
drug resistance /
D-Ala:D-Ser ligase
Community Requests
1E4E
39%
Enterococcus gallinarum
IDP91791
(
show subtarget assignments
)
8
purified
AAA24789
148330
vanH
vancomycin resistance protein [Enterococ...
322
drug resistance /
Dehydrogenase that reduces pyruvate to D-lactate, which is required to produce a...
Community Requests
3KB6
35.7%
Enterococcus faecium
IDP91779
(
show subtarget assignments
)
8
crystallized
AAA26652
153043
lincosamide resistance protein [Staphylo...
161
drug resistance /
Resistance to lincosamides
Community Requests
Staphylococcus haemolyticus
IDP91786
(
show subtarget assignments
)
8
selected
AAA98349
153077
vgh
vgh [Staphylococcus aureus]
299
drug resistance /
Hydrolase inactivating the B components of virginiamycin-like antibiotics
Community Requests
2Z2N
99.3%
Staphylococcus aureus
IDP91056
(
show subtarget assignments
)
8
expressed
AAA42941
323448
viral polyprotein [Dengue virus 2]
3391
potential drug target /
A structure of the co-complex between Dengue 2 strain 16681 full length NS3 and ...
Community Requests
2J7U
15.1%
Dengue virus
IDP00278
(
show subtarget assignments
)
1
selected
AAA99437_1474-2092
323469
N/A
NS3 RNA Helicase
619
Polyprotein processing, RNA replication
Phase 3: June 2008
2VBC
78.9%
Dengue virus
Transcription
N/A
IDP00276
(
show subtarget assignments
)
1
soluble
AAA99437_115-280
323469
N/A
Premembrane/Membrane protein (prM)
166
Very hydrophilic; 6 Cys residues form intramolecular disulfide bonds
Phase 3: June 2008
3C5X
56%
Dengue virus
N/A
IDP00279
(
show subtarget assignments
)
1
selected
AAA99437_2243-2483
323469
N/A
NS4B
241
possibly RNA replication
Phase 3: June 2008
Dengue virus
Transcription
N/A
IDP00277
(
show subtarget assignments
)
1
selected
AAA99437_5-114
323469
N/A
Capsid protein (C)
110
Encapsidation of genomic RNA
Phase 3: June 2008
1R6R
57.3%
Dengue virus
Unclassified
N/A
IDP00265
(
show subtarget assignments
)
1
selected
AAA99437_775-1129
323469
N/A
NS1
355
Secreted from infected cells; stimulates protective immune responses (reason for...
Phase 3: June 2008
Dengue virus
host defense modulator
N/A
IDP91546
(
show subtarget assignments
)
8
selected
AAA26683
398085
vat
acetyltransferase [Staphylococcus aureus...
219
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1KHR
57.5%
Staphylococcus aureus
IDP91868
(
show subtarget assignments
)
8
selected
AAA21889
455437
aac(6')-Ig
aminoglycoside 6'-N-acetyltransferase [A...
145
drug resistance /
confers resistance to aminoglycoside antibiotics by acetylation
Community Requests
1S3Z
40%
Acinetobacter haemolyticus
IDP91869
(
show subtarget assignments
)
8
selected
AAC41391
547387
aac(6')-Ih
aac(6')-Ih [Acinetobacter baumannii]
146
drug resistance /
confers resistance to aminoglycoside antibiotics by acetylation
Community Requests
1S3Z
43.8%
Acinetobacter baumannii
IDP00280
(
show subtarget assignments
)
1
purified
AAX48017_51-545
604449
N/A
Envelope (E)
495
Contains receptor binding sites and fusogenic domain; also contains 12 Cys resid...
Phase 3: June 2008
3UAJ
79.2%
Dengue virus
N/A
IDP91793
(
show subtarget assignments
)
8
purified
BAA03776
807707
mphA
macrolide 2'-phosphotransferase I [Esche...
301
other biological interest /
Kinase
Community Requests
3N4T
19.3%
Escherichia coli
IDP91808
(
show subtarget assignments
)
8
selected
AAB07788
924760
CTCF
CTCF [Homo sapiens]
727
innate immunity /
CTCF (CCCTC-binding factor) is an evolutionarily-conserved transcription factor ...
Community Requests
1X6H
10.2%
Homo sapiens
IDP91871
(
show subtarget assignments
)
8
selected
AAB05624
1209528
vanYB
D,D-carboxypeptidase [Enterococcus faeca...
268
drug resistance /
confers resistance to vancomycin/teicoplanin by hydrolyzing normal cell wall pre...
Community Requests
Enterococcus faecalis
IDP91050
(
show subtarget assignments
)
8
purified
EFE0001
1209531
vanB
D-Ala:D-Lac ligase [Enterococcus faecali...
342
drug resistance /
D-lactate D-ala ligase; generates vancomycin resistant cell wall
Community Requests
1E4E
75.1%
Enterococcus faecalis
IDP91773
(
show subtarget assignments
)
8
purified
AAB05628
1209532
vanXB
D,D-dipeptidase [Enterococcus faecalis]
202
drug resistance /
D,D-dipeptidase
Community Requests
1R44
74.8%
Enterococcus faecalis
IDP91794
(
show subtarget assignments
)
8
crystallized
BAA12910
1695688
mphB
macrolide 2'-phosphotransferase II [Esch...
302
other biological interest /
Kinase
Community Requests
Escherichia coli
IDP91813
(
show subtarget assignments
)
8
selected
b0116
1786307
lpd
lipoamide dehydrogenase, E3 component is...
474
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1BHY
63.6%
Escherichia coli
IDP91820
(
show subtarget assignments
)
8
selected
b0474
1786680
adk
adenylate kinase [Escherichia coli str. ...
214
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1AKE
100%
Escherichia coli
IDP91822
(
show subtarget assignments
)
8
selected
b0755
1786970
gpmA
phosphoglyceromutase 1 [Escherichia coli...
250
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1E59
99.6%
Escherichia coli
IDP91812
(
show subtarget assignments
)
8
selected
b0823
1787044
ybiW
predicted pyruvate formate lyase [Escher...
810
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1R8W
37.1%
Escherichia coli
IDP91824
(
show subtarget assignments
)
8
selected
b1676
1787965
pykF
pyruvate kinase I [Escherichia coli str....
470
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1PKY
99.8%
Escherichia coli
IDP91827
(
show subtarget assignments
)
8
selected
b1723
1788017
pfkB
6-phosphofructokinase II [Escherichia co...
309
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
3CQD
100%
Escherichia coli
IDP91830
(
show subtarget assignments
)
8
selected
b1779
1788079
gapA
glyceraldehyde-3-phosphate dehydrogenase...
331
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1S7C
100%
Escherichia coli
IDP91823
(
show subtarget assignments
)
8
selected
b1854
1788160
pykA
pyruvate kinase II [Escherichia coli str...
480
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
2E28
40.6%
Escherichia coli
IDP91817
(
show subtarget assignments
)
8
selected
b2217
1788546
rcsB
DNA-binding response regulator in two-co...
216
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1P4W
36.6%
Escherichia coli
IDP91826
(
show subtarget assignments
)
8
selected
b2415
1788755
ptsH
phosphohistidinoprotein-hexose phosphotr...
85
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1GGR
100%
Escherichia coli
IDP91816
(
show subtarget assignments
)
8
selected
b2463
1788806
maeB
fused malic enzyme predicted oxidoreduct...
759
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1WW8
26.5%
Escherichia coli
IDP91818
(
show subtarget assignments
)
8
selected
b2584
1788938
yfiQ
inhibiting acetyltransferase for acetyl-...
886
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
2CSU
17.3%
Escherichia coli
IDP91828
(
show subtarget assignments
)
8
selected
b2925
1789293
fbaA
fructose-bisphosphate aldolase, class II...
359
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1B57
99.7%
Escherichia coli
IDP91821
(
show subtarget assignments
)
8
selected
b2926
1789294
pgk
phosphoglycerate kinase [Escherichia col...
387
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1ZMR
100%
Escherichia coli
IDP91814
(
show subtarget assignments
)
8
selected
b3236
1789632
mdh
malate dehydrogenase, NAD(P)-binding [Es...
312
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
2PWZ
100%
Escherichia coli
IDP91810
(
show subtarget assignments
)
8
selected
b3357
1789756
crp
DNA-binding transcriptional dual regulat...
210
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1G6N
100%
Escherichia coli
IDP91825
(
show subtarget assignments
)
8
selected
b3403
1789807
pck
phosphoenolpyruvate carboxykinase [Esche...
540
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1AQ2
100%
Escherichia coli
IDP91811
(
show subtarget assignments
)
8
selected
b3916
1790350
pfkA
6-phosphofructokinase I [Escherichia col...
320
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1PFK
100%
Escherichia coli
IDP91829
(
show subtarget assignments
)
8
selected
b3919
1790353
tpiA
triosephosphate isomerase [Escherichia c...
255
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1TRE
99.6%
Escherichia coli
IDP91815
(
show subtarget assignments
)
8
selected
b3956
1790393
ppc
phosphoenolpyruvate carboxylase [Escheri...
883
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
1FIY
100%
Escherichia coli
IDP91819
(
show subtarget assignments
)
8
selected
b4307
1790761
yjhQ
KpLE2 phage-like element; predicted acet...
181
potential drug target /
The following proteins are either GNAT acetyltransferases thought to acetylate p...
Community Requests
Escherichia coli
IDP91796
(
show subtarget assignments
)
8
purified
AAB49832
1854639
gentamicin resistance protein [Enterococ...
306
other biological interest /
Kinase
Community Requests
3N4V
29.1%
Enterococcus gallinarum
IDP91792
(
show subtarget assignments
)
8
purified
AAB58447
2145190
aph
spectinomycin phosphotransferase [Legion...
331
other biological interest /
Kinase
Community Requests
3I0O
100%
Legionella pneumophila
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