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Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
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Keyword:
Type Keyword
Stage:
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cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
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CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP04046
(
show subtarget assignments
)
1
cloned
YPCD1.78c
16082765
tap
repA translation protein [Yersinia pesti...
24
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP90972
(
show subtarget assignments
)
8
selected
ECO103_4485
260846542
tisB
lexA-regulated toxic peptide [Escherichi...
29
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Escherichia coli
IDP05413
(
show subtarget assignments
)
1
cloned
BA_3890
30258404
hypothetical protein BA_3890 [Bacillus a...
30
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05003
(
show subtarget assignments
)
1
cloned
BA_3309
30257855
hypothetical protein BA_3309 [Bacillus a...
31
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05389
(
show subtarget assignments
)
1
cloned
BA_2660
30257276
hypothetical protein BA_2660 [Bacillus a...
31
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05432
(
show subtarget assignments
)
1
cloned
BA_2714
30257323
hypothetical protein BA_2714 [Bacillus a...
31
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04098
(
show subtarget assignments
)
1
cloned
YPCD1.50
5832470
YPCD1.50
hypothetical protein YPCD1.50 [Yersinia ...
32
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP00853
(
show subtarget assignments
)
1
purified
STM0359
16763739
putative cytoplasmic protein
33
Conserved Gene / Pathway
Phase 2: March 2008
Salmonella enterica
Protein synthesis
tRNA aminoacylation
IDP05004
(
show subtarget assignments
)
1
cloned
CDP01
110666923
hypothetical protein CDP01 [Clostridium ...
33
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP05005
(
show subtarget assignments
)
1
cloned
CDP11
110666933
hypothetical protein CDP11 [Clostridium ...
33
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP05033
(
show subtarget assignments
)
1
cloned
BA_1260
30255209
hypothetical protein BA_1260 [Bacillus a...
34
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05608
(
show subtarget assignments
)
1
cloned
BA_5124
30259608
hypothetical protein BA_5124 [Bacillus a...
35
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91335
(
show subtarget assignments
)
8
cloned
VV2_0153
27366609
hypothetical protein VV2_0153 [Vibrio vu...
35
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP05400
(
show subtarget assignments
)
1
cloned
BA_0243
30253741
hypothetical protein BA_0243 [Bacillus a...
36
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05482
(
show subtarget assignments
)
1
cloned
BA_3956
30258466
hypothetical protein BA_3956 [Bacillus a...
36
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05593
(
show subtarget assignments
)
1
cloned
BA_3215
30257781
hypothetical protein BA_3215 [Bacillus a...
37
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04137
(
show subtarget assignments
)
1
soluble
BAS0134
49183168
50S ribosomal protein L36 [Bacillus anth...
37
Proposed to be essential proteins
Phase 4: April 2009
1DFE
81.1%
Bacillus anthracis
IDP05477
(
show subtarget assignments
)
1
cloned
BA_2770
30257374
hypothetical protein BA_2770 [Bacillus a...
38
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91347
(
show subtarget assignments
)
8
cloned
VV1_3162
27366424
hypothetical protein VV1_3162 [Vibrio vu...
39
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP05396
(
show subtarget assignments
)
1
cloned
BA_3329
30257874
hypothetical protein BA_3329 [Bacillus a...
41
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP02461
(
show subtarget assignments
)
1
cloned
Cj0176c
15791563
putative lipoprotein [Campylobacter jeju...
43
Predicted virulence-Iron Scavenging Mechanisms
Phase 3: June 2008
Campylobacter jejuni
Transport and binding proteins
Cations and iron carrying compounds
IDP00846
(
show subtarget assignments
)
1
cloned
SACOL1177
57284462
hypothetical protein SACOL1177
43
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP00842
(
show subtarget assignments
)
1
soluble
SACOL1186
57284471
antibacterial protein (phenol soluble mo...
44
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
Unknown function
General
IDP05256
(
show subtarget assignments
)
1
cloned
BA_1805
30256080
hypothetical protein BA_1805 [Bacillus a...
44
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05376
(
show subtarget assignments
)
1
cloned
BA_4131
30258637
hypothetical protein BA_4131 [Bacillus a...
44
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05480
(
show subtarget assignments
)
1
cloned
BA_3532
30258067
putative lipoprotein [Bacillus anthracis...
44
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04307
(
show subtarget assignments
)
1
cloned
CPF_1812
110799901
putative lipoprotein [Clostridium perfri...
44
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
IDP05397
(
show subtarget assignments
)
1
purified
BA_3670
30258191
sspN
small, acid-soluble spore protein N [Bac...
44
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP05458
(
show subtarget assignments
)
1
cloned
BA_0431
30253964
hypothetical protein BA_0431 [Bacillus p...
44
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04732
(
show subtarget assignments
)
1
cloned
BAS5341
49188325
50S ribosomal protein L34 [Bacillus anth...
44
Proposed to be essential proteins
Phase 4: April 2009
1NKW
65.9%
Bacillus anthracis
IDP00854
(
show subtarget assignments
)
1
cloned
STM1810
16765151
putative cytoplasmic protein
45
Conserved Gene / Pathway
Phase 2: March 2008
Salmonella enterica
Protein synthesis
tRNA aminoacylation
IDP05487
(
show subtarget assignments
)
1
expressed
BA_4765
30259252
hypothetical protein BA_4765 [Bacillus a...
46
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90390
(
show subtarget assignments
)
8
cloned
CT_377
3328802
ltuA
hypothetical protein [Chlamydia trachoma...
46
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP05018
(
show subtarget assignments
)
1
purified
BA_2679
30257293
hypothetical protein BA_2679 [Bacillus a...
47
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP00622
(
show subtarget assignments
)
1
cloned
SACOL1878
57284798
epiA
lantibiotic epidermin precursor EpiA
47
Conserved Gene / Pathway
Phase 2: March 2008
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP05032
(
show subtarget assignments
)
1
cloned
BA_1198
30255151
hypothetical protein BA_1198 [Bacillus a...
47
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05373
(
show subtarget assignments
)
1
cloned
BA_3146
30257723
hypothetical protein BA_3146 [Bacillus a...
47
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP00601
(
show subtarget assignments
)
1
cloned
SACOL0893
57284352
pathogenicity island protein
48
Conserved Gene / Pathway
Phase 2: March 2008
Staphylococcus aureus
Cellular processes
Pathogenesis
IDP00023
(
show subtarget assignments
)
1
cloned
BA_5594
30260051
papR
PapR
48
Drug Target Homolog
Phase 1: October 2007
Bacillus anthracis
Cellular processes
Pathogenesis
IDP05720
(
show subtarget assignments
)
1
expressed
BA_2461
30257091
hypothetical protein BA_2461 [Bacillus a...
48
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP00864
(
show subtarget assignments
)
1
soluble
STM1268
16764619
putative cytoplasmic protein
49
Conserved Gene / Pathway
Phase 2: March 2008
Salmonella enterica
Protein synthesis
tRNA aminoacylation
IDP05278
(
show subtarget assignments
)
1
cloned
BA_5456
30259924
hypothetical protein BA_5456 [Bacillus a...
49
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05603
(
show subtarget assignments
)
1
cloned
BA_4709
30259202
hypothetical protein BA_4709 [Bacillus a...
50
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP00886
(
show subtarget assignments
)
1
cloned
STM2329
16765656
putative cytoplasmic protein
50
Conserved Gene / Pathway
Phase 2: March 2008
Salmonella enterica
Protein synthesis
tRNA aminoacylation
IDP00882
(
show subtarget assignments
)
1
cloned
STM1649
16764993
putative cytoplasmic protein
51
Conserved Gene / Pathway
Phase 2: March 2008
Salmonella enterica
Cell envelope
Other
IDP05581
(
show subtarget assignments
)
1
cloned
BA_1407
30255341
hypothetical protein BA_1407 [Bacillus a...
51
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP00600
(
show subtarget assignments
)
1
cloned
SACOL0532
57285557
hypothetical protein SACOL0532
51
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP05391
(
show subtarget assignments
)
1
cloned
BA_2630
30257247
conserved hypothetical protein [Bacillus...
51
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP05017
(
show subtarget assignments
)
1
cloned
BA_2521
30257145
putative lipoprotein [Bacillus anthracis...
52
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP90334
(
show subtarget assignments
)
8
cloned
CT_421.2
3522896
hypothetical protein [Chlamydia trachoma...
53
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90332
(
show subtarget assignments
)
8
cloned
CT_421.1
3522895
hypothetical protein [Chlamydia trachoma...
53
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP02707
(
show subtarget assignments
)
1
cloned
STM3237
16766536
yhaL
putative cytoplasmic protein [Salmonella...
54
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01687
(
show subtarget assignments
)
1
cloned
Cj0740
15792089
hypothetical protein Cj0740 [Campylobact...
54
Predicted virulence-Adhesion of Campylobacter
Phase 3: June 2008
Campylobacter jejuni
Transport and binding proteins
Amino acids, peptides and amines
IDP05383
(
show subtarget assignments
)
1
purified
BA_1433
30255366
hypothetical protein BA_1433 [Bacillus a...
55
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90944
(
show subtarget assignments
)
8
cloned
STM1121
16764478
ymdF
putative cytoplasmic protein [Salmonella...
55
This is a protein with experimental and computational evidence for being secrete...
Community Requests
Salmonella enterica
IDP04031
(
show subtarget assignments
)
1
cloned
CBU_A0011
29648123
hypothetical protein CBUA0011 [Coxiella ...
56
drug target;
Phase 4: April 2009
Coxiella burnetii
Hypothetical proteins
Domain
IDP05006
(
show subtarget assignments
)
1
cloned
BA_3083
30257668
putative lipoprotein [Bacillus anthracis...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05365
(
show subtarget assignments
)
1
expressed
BA_2909
30257501
hypothetical protein BA_2909 [Bacillus a...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90105
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_008
68449082
unknown [Monkeypox virus]
56
similar to part of CPXV-GRI-C3L
Community Requests
Monkeypox virus
IDP05392
(
show subtarget assignments
)
1
cloned
BA_3222
30257786
hypothetical protein BA_3222 [Bacillus a...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05447
(
show subtarget assignments
)
1
expressed
BA_0441
30253974
conserved hypothetical protein [Bacillus...
57
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP05416
(
show subtarget assignments
)
1
purified
BA_4778
30259264
hypothetical protein BA_4778 [Bacillus a...
57
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91628
(
show subtarget assignments
)
8
soluble
BAB34989
13361030
ECs1566
hypothetical protein [Escherichia coli O...
57
virulence/pathogenesis /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Escherichia coli
IDP02509
(
show subtarget assignments
)
1
crystallized
STM1809
16765150
putative cytoplasmic protein [Salmonella...
57
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02051
(
show subtarget assignments
)
1
cloned
STM4141
16767399
putative cytoplasmic protein [Salmonella...
57
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP05375
(
show subtarget assignments
)
1
expressed
BA_4118
30258624
hypothetical protein BA_4118 [Bacillus a...
57
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP01945
(
show subtarget assignments
)
1
cloned
Cj0739
15792088
hypothetical protein Cj0739 [Campylobact...
57
Predicted virulence-Adhesion of Campylobacter
Phase 3: June 2008
Campylobacter jejuni
Central intermediary metabolism
Other
IDP05467
(
show subtarget assignments
)
1
expressed
BA_1769
30256048
hypothetical protein BA_1769 [Bacillus a...
58
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91339
(
show subtarget assignments
)
8
cloned
VV2_0109
27366566
hypothetical protein VV2_0109 [Vibrio vu...
58
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP90335
(
show subtarget assignments
)
8
soluble
CT_652.1
3522906
hypothetical protein [Chlamydia trachoma...
59
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP01876
(
show subtarget assignments
)
1
cloned
GBAA0095
47525349
secE
preprotein translocase subunit SecE [Bac...
59
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
3DIN
33.9%
Bacillus anthracis
Protein fate
Protein and peptide secretion and trafficking
IDP05026
(
show subtarget assignments
)
1
cloned
BA_0025
30253539
putative csfB protein [Bacillus anthraci...
59
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05016
(
show subtarget assignments
)
1
soluble
BA_2056
30256706
putative lipoprotein [Bacillus anthracis...
59
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP04022
(
show subtarget assignments
)
1
cloned
BAS0095
49183129
preprotein translocase subunit SecE [Bac...
59
Proposed to be essential proteins
Phase 4: April 2009
3DIN
33.9%
Bacillus anthracis
IDP91626
(
show subtarget assignments
)
8
cloned
BAB34550
13360587
ECs1127
hypothetical protein [Escherichia coli O...
60
virulence/pathogenesis /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Escherichia coli
IDP01755
(
show subtarget assignments
)
1
cloned
STM1728
16765072
yciG
putative cytoplasmic protein [Salmonella...
60
Essential; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP04034
(
show subtarget assignments
)
1
purified
BAS0128
49183162
50S ribosomal protein L30 [Bacillus anth...
60
Proposed to be essential proteins
Phase 4: April 2009
1VS6
53.3%
Bacillus anthracis
IDP05356
(
show subtarget assignments
)
1
cloned
BA_3897
30258411
conserved domain protein [Bacillus anthr...
61
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Domain
IDP02642
(
show subtarget assignments
)
1
cloned
GBAA5626
47778419
4-oxalocrotonate tautomerase [Bacillus a...
61
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
2OP8
78.7%
Bacillus anthracis
Energy metabolism
Other
IDP04080
(
show subtarget assignments
)
1
cloned
BAS0123
49183157
30S ribosomal protein S14 [Bacillus anth...
61
Proposed to be essential proteins
Phase 4: April 2009
1FJG
73.8%
Bacillus anthracis
IDP05377
(
show subtarget assignments
)
1
soluble
BA_3611
30258139
hypothetical protein BA_3611 [Bacillus a...
61
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90336
(
show subtarget assignments
)
8
cloned
CT_849.1
3522913
hypothetical protein [Chlamydia trachoma...
62
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP05221
(
show subtarget assignments
)
1
expressed
BA_4349
30258849
hypothetical protein BA_4349 [Bacillus a...
62
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05374
(
show subtarget assignments
)
1
cloned
BA_3570
30258098
hypothetical protein BA_3570 [Bacillus a...
63
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP01027
(
show subtarget assignments
)
1
purified
STM1346
16764697
ydiE
hypothetical protein STM1346
63
Conserved Gene / Pathway
Phase 2: March 2008
Salmonella enterica
Protein synthesis
tRNA aminoacylation
IDP00872
(
show subtarget assignments
)
1
cloned
STM0138
16763528
yacG
zinc-binding protein
63
Conserved Gene / Pathway
Phase 2: March 2008
1LV3
85.7%
Salmonella enterica
Protein synthesis
tRNA aminoacylation
IDP90179
(
show subtarget assignments
)
8
cloned
AAM13473.1
20153012
CPXV025 CDS
CPXV026 protein
63
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP01313
(
show subtarget assignments
)
1
purified
VCA0446
15601209
haemagglutinin
63
Virulence Associated Factor
Phase 2: March 2008
Vibrio cholerae
Cellular processes
Pathogenesis
IDP91321
(
show subtarget assignments
)
8
cloned
VV2_0305
27366749
hypothetical protein VV2_0305 [Vibrio vu...
64
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP05736
(
show subtarget assignments
)
1
soluble
CD1702A
126699309
thiS
putative thiamine biosynthesis protein [...
64
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1TYG
41.5%
Clostridium difficile
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
IDP00917
(
show subtarget assignments
)
1
cloned
STM0355
16763735
putative copper chaperone
64
Conserved Gene / Pathway
Phase 2: March 2008
2K2P
39.1%
Salmonella enterica
Transport and binding proteins
Cations and iron carrying compounds
IDP05041
(
show subtarget assignments
)
1
purified
BA_2335
30256973
hypothetical protein BA_2335 [Bacillus a...
64
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP01102
(
show subtarget assignments
)
1
soluble
BA_5424
49040749
Cold shock-like protein cspC
65
Essential Gene
Phase 2: March 2008
1C9O
74.2%
Bacillus anthracis
Cellular processes
Adaptations to atypical conditions
IDP04308
(
show subtarget assignments
)
1
cloned
YPCD1.14n
40548797
hypothetical protein YPCD1.14n [Yersinia...
65
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP02050
(
show subtarget assignments
)
1
soluble
STM4365
16767611
yjeT
putative inner membrane protein [Salmone...
65
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP04135
(
show subtarget assignments
)
1
cloned
BAS4470
49187465
50S ribosomal protein L35 [Bacillus anth...
66
Proposed to be essential proteins
Phase 4: April 2009
1VS6
48.5%
Bacillus anthracis
IDP00630
(
show subtarget assignments
)
1
cloned
SACOL0861
57284322
cold shock protein, CSD family
66
Conserved Gene / Pathway
Phase 2: March 2008
2I5M
71.2%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP00623
(
show subtarget assignments
)
1
cloned
SACOL2731
57285285
cold shock protein, CSD family
66
Conserved Gene / Pathway
Phase 2: March 2008
2I5M
68.2%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP02637
(
show subtarget assignments
)
1
purified
STM1867
16765207
pagK
PagK [Salmonella typhimurium LT2]
66
Drug target functions
Phase 3: June 2008
Salmonella enterica
Unclassified
Role category not yet assigned
IDP02757
(
show subtarget assignments
)
1
cloned
STM2484
16765804
hypothetical protein STM2484 [Salmonella...
66
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
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