Home
Target List
Selection
Community Requests
Clones
XML files
Diffraction Images
Progress
Homolog Search
Clustering
Statistics
News
Help
Log In
Consortium
Overview
Investigators
Experiments
X-ray Structures
NMR Structures
Electronic Structure Description
Publications
Resources
Clustering
Related Sites
Progress
Collaborators
Basecamp
Contact Us
Log In
Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
In
IDP#
NCBI GI
LOCUS TAG
Search
Page 1 of 60, showing 100 records out of 5960 total, starting on record 1
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP91511
(
show subtarget assignments
)
8
cloned
VV2_0479
27366913
autotransporter adhesin [Vibrio vulnific...
5206
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
3EEB
3.7%
Vibrio vulnificus
IDP91806
(
show subtarget assignments
)
8
selected
ZP_04520447
237507732
putative polyketide synthase PksJ (PKS) ...
5053
virulence/pathogenesis /
Emerging evidence suggests that natural products from pathogenic organisms are i...
Community Requests
2VSQ
5.6%
Burkholderia pseudomallei
IDP05461
(
show subtarget assignments
)
1
selected
BA_1618
30255916
conserved repeat domain protein [Bacillu...
5017
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP91804
(
show subtarget assignments
)
8
selected
ZP_04523236
237510521
putative polyketide synthase PksL (PKS) ...
4567
virulence/pathogenesis /
Emerging evidence suggests that natural products from pathogenic organisms are i...
Community Requests
2HG4
5.4%
Burkholderia pseudomallei
IDP91805
(
show subtarget assignments
)
8
selected
GBP346_B0724
235002726
putative polyketide synthase PksL (PKS) ...
4567
virulence/pathogenesis /
Emerging evidence suggests that natural products from pathogenic organisms are i...
Community Requests
2HG4
5.4%
Burkholderia pseudomallei
IDP00167
(
show subtarget assignments
)
8
in_pdb
3FZY
VC1451
4455065
rtxA
RTX toxin RtxA
4545
Virulence
Community Requests
3EEB
4.6%
Vibrio cholerae
Cellular processes
Pathogenesis
IDP91660
(
show subtarget assignments
)
8
selected
LAMA5_HUMAN
0
3695
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2Y38
9.6%
Homo sapiens
IDP91056
(
show subtarget assignments
)
8
expressed
AAA42941
323448
viral polyprotein [Dengue virus 2]
3391
potential drug target /
A structure of the co-complex between Dengue 2 strain 16681 full length NS3 and ...
Community Requests
2J7U
15.1%
Dengue virus
IDP00192
(
show subtarget assignments
)
1
cloned
YPO0947
16121251
-
putative virulence determinant
3110
Virulence
Phase 1: October 2007
1AF0
2.9%
Yersinia pestis
Unknown function
Enzymes of unknown specificity
IDP91663
(
show subtarget assignments
)
8
selected
NP_005550
38788416
LAMA1
laminin subunit alpha-1 precursor [Homo ...
3075
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2JD4
9.4%
Homo sapiens
IDP91758
(
show subtarget assignments
)
8
selected
VWF_HUMAN
0
2813
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1SQ0
7.5%
Homo sapiens
IDP05285
(
show subtarget assignments
)
1
selected
CD0663
126698240
tcdA
toxin A [Clostridium difficile 630]
2710
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3SRZ
20%
Clostridium difficile
Cellular processes: Pathogenesis
IDP92058
(
show subtarget assignments
)
8
selected
ACN59873
224590780
prex
plastid replication-repair enzyme [Toxop...
2579
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP00401
(
show subtarget assignments
)
1
cloned
YPO2490
161486873
putative hemolysin
2531
Virulence Associated Factor
Phase 2: March 2008
1RWR
3.9%
Yersinia pestis
Viral functions
General
IDP00168
(
show subtarget assignments
)
1
cloned
VC2209
15642774
vibF
nonribosomal peptide synthetase VibF, au...
2413
Virulence
Phase 1: October 2007
2VSQ
10.2%
Vibrio cholerae
Cellular processes
Toxin production and resistance
IDP05371
(
show subtarget assignments
)
1
selected
BA_3601
30258129
conserved repeat domain protein [Bacillu...
2358
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP91983
(
show subtarget assignments
)
8
selected
SpneCM_010100000697
298254118
beta-galactosidase [Streptococcus pneumo...
2233
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3GM8
12.4%
Streptococcus pneumoniae
IDP05456
(
show subtarget assignments
)
1
selected
BA_1094
30254824
putative wall-associated protein [Bacill...
2224
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP91668
(
show subtarget assignments
)
8
selected
Q914E0_9ENTO
0
2194
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2IJD
20.6%
Human echovirus
IDP91667
(
show subtarget assignments
)
8
selected
POLG_CXB3W
0
2185
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2IJD
20.7%
Coxsackievirus B3
IDP91916
(
show subtarget assignments
)
8
selected
SpneCM_010100001122
298254201
spermidine/putrescine ABC transporter, p...
2168
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3D31
3.1%
Streptococcus pneumoniae
IDP91981
(
show subtarget assignments
)
8
selected
SpneCM_010100000172
298254015
serine protease [Streptococcus pneumonia...
2143
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3AFG
5.5%
Streptococcus pneumoniae
IDP05573
(
show subtarget assignments
)
1
selected
BAS4798
49187788
-
cell surface protein, anchor [Bacillus a...
2025
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
DNA metabolism: DNA replication, recombination, and repair
IDP05752
(
show subtarget assignments
)
1
selected
lmo0435
16802479
-
peptidoglycan binding protein [Listeria ...
2013
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Unclassified: Role category not yet assigned
IDP92143
(
show subtarget assignments
)
8
selected
TGME49_068560
237832503
RAD2 endonuclease, putative [Toxoplasma ...
2004
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP91942
(
show subtarget assignments
)
8
selected
SpneCM_010100007536
298255438
immunoglobulin A1 protease [Streptococcu...
2004
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91521
(
show subtarget assignments
)
8
selected
TGME49_040910
237834825
C2 domain-containing protein [Toxoplasma...
1990
potential drug target; virulence/pathogenesis /
DOC2.1 was identified in a temperature sensitive host cell invasion/egress mutan...
Community Requests
Toxoplasma gondii
IDP05002
(
show subtarget assignments
)
1
selected
lmo0086
16802134
-
hypothetical protein lmo0086 [Listeria m...
1959
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP91906
(
show subtarget assignments
)
8
selected
SpneCMD_010100004020
298229824
zinc metalloprotease ZmpB [Streptococcus...
1902
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91665
(
show subtarget assignments
)
8
selected
NP_620278
20357588
TAF1
transcription initiation factor TFIID su...
1872
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3AAD
15.4%
Homo sapiens
IDP91696
(
show subtarget assignments
)
8
selected
NP_002283
119703755
LAMB2
laminin subunit beta-2 precursor [Homo s...
1798
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2Y38
7.3%
Homo sapiens
IDP05663
(
show subtarget assignments
)
1
selected
lmo0333
16802378
-
hypothetical protein lmo0333 [Listeria m...
1778
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1ZIW
9.1%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP91527
(
show subtarget assignments
)
8
cloned
AAX13509
89214483
etpA
EtpA [Escherichia coli ETEC H10407]
1767
virulence/pathogenesis /
The EtpA ETEC two-partner secretion (TPS) exoprotein [PMID: 16552055] is a highl...
Community Requests
3AK5
11.2%
Escherichia coli
IDP90328
(
show subtarget assignments
)
8
cloned
CT_413
3328841
pmpB
Putative outer membrane protein B [Chlam...
1751
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP05105
(
show subtarget assignments
)
1
cloned
CD1374
126698975
hypothetical protein CD1374 [Clostridium...
1743
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1A12
5.3%
Clostridium difficile
Regulatory functions: Other
IDP05690
(
show subtarget assignments
)
1
cloned
lmo1666
16803706
-
peptidoglycan linked protein (LPXTG) [Li...
1711
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Protein fate: Degradation of proteins, peptides, and glycopeptides
IDP90274
(
show subtarget assignments
)
8
selected
TGME49_015260
211968509
carbamoyl phosphate synthetase II [Toxop...
1699
Mutation of the rate-limiting enzyme carbamoyl phosphate synthetase II (CPSII) d...
Community Requests
1A9X
27.1%
Toxoplasma gondii
IDP91543
(
show subtarget assignments
)
8
selected
TGME49_057080
237831315
cAMP-specific 3',5'-cyclic phosphodieste...
1691
potential drug target /
Phosphodiesterases are key regulators of cell signalling pathways and are attrac...
Community Requests
3ECM
6.6%
Toxoplasma gondii
IDP92142
(
show subtarget assignments
)
8
selected
TGME49_112230
237830295
DNA topoisomerase II, putative [Toxoplas...
1687
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP91639
(
show subtarget assignments
)
8
cloned
NP_216896
15609517
peptide synthetase MBTE (peptide synthas...
1682
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2VSQ
17.7%
Mycobacterium tuberculosis
IDP01769
(
show subtarget assignments
)
1
soluble
STM2532
16765852
putative inner membrane lipoprotein [Sal...
1644
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP00514
(
show subtarget assignments
)
1
selected
YPO3721
16123859
hemolysin
1635
Conserved Gene / Pathway
Phase 2: March 2008
3FY3
9%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP05618
(
show subtarget assignments
)
1
cloned
CD0514
126698095
cell surface protein (putative hemagglut...
1630
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05697
(
show subtarget assignments
)
1
cloned
lmo2178
16804217
-
peptidoglycan binding protein [Listeria ...
1599
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3KPT
6.9%
Listeria monocytogenes
Regulatory functions: Other
IDP91681
(
show subtarget assignments
)
8
selected
LAMC3_HUMAN
0
1587
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2Y38
8.9%
Homo sapiens
IDP05754
(
show subtarget assignments
)
1
cloned
lmo0627
16802669
-
pepdidoglycan bound protein [Listeria mo...
1582
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1D2P
8.4%
Listeria monocytogenes
Energy metabolism: Electron transport
IDP00502
(
show subtarget assignments
)
1
selected
YPO2045
16122284
putative hemolysin
1576
Conserved Gene / Pathway
Phase 2: March 2008
3FY3
5.6%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP02086
(
show subtarget assignments
)
1
cloned
YPO3557
161486860
gltB
glutamate synthase subunit alpha [Yersin...
1538
Conserved; CD; Involved in virulence; Drug target functions
Phase 3: June 2008
1EA0
45%
Yersinia pestis
Amino acid biosynthesis
Glutamate family
IDP90430
(
show subtarget assignments
)
8
cloned
CT_812
3329279
pmpD
Putative Outer Membrane Protein D [Chlam...
1531
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP05567
(
show subtarget assignments
)
1
cloned
lmo2576
16804614
-
pepdidoglycan bound protein [Listeria mo...
1530
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3KPT
7.5%
Listeria monocytogenes
Cell envelope: Other
IDP04413
(
show subtarget assignments
)
1
cloned
VC2373
15642370
glutamate synthase, large subunit [Vibri...
1530
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1LLW
44.6%
Vibrio cholerae
Amino acid biosynthesis
Glutamate family
IDP91701
(
show subtarget assignments
)
8
selected
NP_003053
11321571
SLIT3
slit homolog 3 protein precursor [Homo s...
1523
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2A0Z
11.2%
Homo sapiens
IDP90573
(
show subtarget assignments
)
8
cloned
Cj0479
15791843
rpoC
DNA-directed RNA polymerase beta' chain ...
1517
Predicted Essential
Community Requests
3IYD
46.1%
Campylobacter jejuni
IDP91690
(
show subtarget assignments
)
8
selected
NP_001008537
56711286
KIAA2022
hypothetical protein LOC340533 [Homo sap...
1516
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
Homo sapiens
IDP90302
(
show subtarget assignments
)
0
work_stopped
BB_0420
2688313
sensory transduction histidine kinase, p...
1494
Mutational studies suggest that Hk1 is required for the survival of the Lyme dis...
Community Requests
3A0R
5.6%
Borrelia burgdorferi
IDP01053
(
show subtarget assignments
)
1
cloned
STM3330
16766625
gltB
glutamate synthase subunit alpha
1486
Conserved Gene / Pathway
Phase 2: March 2008
1EA0
45.2%
Salmonella enterica
Central intermediary metabolism
Other
IDP01627
(
show subtarget assignments
)
1
cloned
GBAA0530
50196914
glutamate synthase, large subunit, putat...
1478
Conserved; Drug target functions
Phase 3: June 2008
1EA0
29.7%
Bacillus anthracis
Amino acid biosynthesis
Glutamate family
IDP92141
(
show subtarget assignments
)
8
selected
TGME49_066730
237838909
leucyl-tRNA synthetase, putative [Toxopl...
1465
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP91642
(
show subtarget assignments
)
8
cloned
NP_216895
15609516
peptide synthetase MBTF (peptide synthas...
1461
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2VSQ
20.2%
Mycobacterium tuberculosis
IDP90282
(
show subtarget assignments
)
8
selected
TGME49_013640
211968765
splicing factor, arginine/serine-rich 4,...
1461
Unpublished data from a differentiation mutagenesis screen indicate that the spl...
Community Requests
Toxoplasma gondii
IDP91641
(
show subtarget assignments
)
8
cloned
NP_216899
15609520
phenyloxazoline synthase MBTB (phenyloxa...
1414
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2VSQ
23.6%
Mycobacterium tuberculosis
IDP04533
(
show subtarget assignments
)
1
cloned
STM4154_1_1407
16767408
rpoC
DNA-directed RNA polymerase subunit beta...
1407
Salmonella essential protein
Phase 4: April 2009
3IYD
98.6%
Salmonella enterica
IDP90825
(
show subtarget assignments
)
8
selected
S3674
30064729
rpoC
DNA-directed RNA polymerase subunit beta...
1407
Predicted Essential
Community Requests
3IYD
100%
Shigella flexneri
IDP90622
(
show subtarget assignments
)
0
work_stopped
YPO3746
16123883
rpoC
DNA-directed RNA polymerase subunit beta...
1406
Predicted Essential
Community Requests
3IYD
92.7%
Yersinia pestis
IDP90881
(
show subtarget assignments
)
8
expressed
VC0329
15640356
DNA-directed RNA polymerase subunit beta...
1401
Predicted Essential
Community Requests
3IYD
82.4%
Vibrio cholerae
IDP91686
(
show subtarget assignments
)
8
selected
NP_000236
42741655
MET
hepatocyte growth factor receptor isofor...
1390
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2UZX
51.4%
Homo sapiens
IDP91037
(
show subtarget assignments
)
8
cloned
SAHV_0560
156978891
sdrD
Ser-Asp rich fibrinogen-binding, bone si...
1385
virulence/pathogenesis /
Sdr family proteins are interesting cell surface proteins in Staphylococcus aure...
Community Requests
3IS1
8.5%
Staphylococcus aureus
IDP90699
(
show subtarget assignments
)
8
cloned
Cj0478
15791842
rpoB
DNA-directed RNA polymerase subunit beta...
1378
Predicted Essential
Community Requests
3IYD
47.9%
Campylobacter jejuni
IDP91685
(
show subtarget assignments
)
8
selected
NP_000080
48762934
COL1A2
collagen alpha-2(I) chain precursor [Hom...
1366
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3HQV
63.6%
Homo sapiens
IDP04414
(
show subtarget assignments
)
8
selected
CAC05786
12329055
sepA
SepA, extracellular serine protease of t...
1364
Shigella effector protein
Community Requests
1WXR
34.9%
Shigella flexneri
IDP01916
(
show subtarget assignments
)
1
cloned
lmo0327
16802372
hypothetical protein lmo0327 [Listeria m...
1348
Predicted virulence-Invasion; Predicted involvement or location on the cell wall...
Phase 3: June 2008
3M18
3.5%
Listeria monocytogenes
Central intermediary metabolism
Other
IDP02312
(
show subtarget assignments
)
1
expressed
GBAA2190
47778017
FtsK/SpoIIIE family protein [Bacillus an...
1342
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
2IUT
7.4%
Bacillus anthracis
Cellular processes
Cell division
IDP90917
(
show subtarget assignments
)
8
expressed
Q9KV30
41019520
RecName: Full=DNA-directed RNA polymeras...
1341
Predicted Essential
Community Requests
3IYD
85.3%
Vibrio cholerae
IDP92140
(
show subtarget assignments
)
8
selected
TGME49_072740
237833217
DNA-directed RNA polymerase III subunit,...
1332
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP04163
(
show subtarget assignments
)
1
expressed
VC1349
15641361
sensory box sensor histidine kinase/resp...
1331
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
2C2A
6.5%
Vibrio cholerae
Regulatory functions
Other
IDP91713
(
show subtarget assignments
)
8
selected
NP_006668
57529246
USP19
ubiquitin carboxyl-terminal hydrolase 19...
1318
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1WH0
9.3%
Homo sapiens
IDP91950
(
show subtarget assignments
)
8
selected
SpneCM_010100006639
298255269
beta-N-acetylhexosaminidase [Streptococc...
1312
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3RPM
35.5%
Streptococcus pneumoniae
IDP05083
(
show subtarget assignments
)
1
cloned
lmo2444
16804482
-
hypothetical protein lmo2444 [Listeria m...
1310
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3LPO
13.1%
Listeria monocytogenes
Central intermediary metabolism: Other
IDP04398
(
show subtarget assignments
)
1
cloned
YPO1376
218928524
ftsK
putative cell division protein [Yersinia...
1305
drug target; putative drug target function;
Phase 4: April 2009
2IUS
33.3%
Yersinia pestis
Cellular processes
Cell division
IDP04499
(
show subtarget assignments
)
1
cloned
VC0869
15640885
phosphoribosylformylglycinamidine syntha...
1297
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1T3T
73.9%
Vibrio cholerae
Purines, pyrimidines, nucleosides, and nucleotides
Purine ribonucleotide biosynthesis
IDP04400
(
show subtarget assignments
)
1
cloned
YPO2921
218929976
purL
phosphoribosylformylglycinamidine syntha...
1296
conserved gene; putative drug target function;
Phase 4: April 2009
1T3T
82.5%
Yersinia pestis
Purines, pyrimidines, nucleosides, and nucleotides
Purine ribonucleotide biosynthesis
IDP04656
(
show subtarget assignments
)
1
cloned
FTT1720c
56708726
purL
phosphoribosylformylglycinamidine syntha...
1290
conserved gene; putative drug target function;
Phase 4: April 2009
1T3T
55.8%
Francisella tularensis
Purines, pyrimidines, nucleosides, and nucleotides
Purine ribonucleotide biosynthesis
IDP92139
(
show subtarget assignments
)
8
selected
TGME49_058030
237831459
DNA polymerase delta catalytic subunit, ...
1268
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92138
(
show subtarget assignments
)
8
selected
TGME49_073450
237833297
sufB/sufD domain-containing protein [Tox...
1267
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP04192
(
show subtarget assignments
)
1
cloned
CPF_0671
110799768
phosphoribosylformylglycinamidine syntha...
1266
conserved gene; putative drug target function;
Phase 4: April 2009
3AC6
15.2%
Clostridium perfringens
Purines, pyrimidines, nucleosides, and nucleotides
Purine ribonucleotide biosynthesis
IDP92137
(
show subtarget assignments
)
8
selected
TGME49_097780
237843801
DNA gyrase subunit B, putative [Toxoplas...
1257
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP90955
(
show subtarget assignments
)
8
purified
PA14_07500
122261554
Hypothetical protein
1245
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
2R6O
10.6%
Pseudomonas aeruginosa
IDP02636
(
show subtarget assignments
)
1
expressed
YPO3722
16123860
metH
B12-dependent methionine synthase [Yersi...
1231
CD; Drug target functions
Phase 3: June 2008
1K7Y
40.1%
Yersinia pestis
Amino acid biosynthesis
Aspartate family
IDP90903
(
show subtarget assignments
)
8
purified
VC0390
15640417
metH
B12-dependent methionine synthase [Vibri...
1226
Predicted Essential
Community Requests
3BUL
33.8%
Vibrio cholerae
IDP04580
(
show subtarget assignments
)
1
cloned
BAS0103
49183137
DNA-directed RNA polymerase subunit beta...
1203
Proposed to be essential proteins
Phase 4: April 2009
2GHO
53.6%
Bacillus anthracis
IDP90624
(
show subtarget assignments
)
8
cloned
Cj0718
15792067
dnaE
DNA polymerase III subunit alpha [Campyl...
1200
Predicted Essential
Community Requests
2HPI
37%
Campylobacter jejuni
IDP05536
(
show subtarget assignments
)
1
cloned
CD3145
126700762
putative serine-aspartate-rich surface a...
1190
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1YO8
7.6%
Clostridium difficile
Unknown function: General
IDP00797
(
show subtarget assignments
)
1
expressed
SACOL1250
57285989
chromosome segregation SMC protein, puta...
1188
Conserved Gene / Pathway
Phase 2: March 2008
1W1W
7.5%
Staphylococcus aureus
Cellular processes
Cell division
IDP90660
(
show subtarget assignments
)
8
cloned
Cj1476c
15792791
pyruvate ferredoxin/flavodoxin oxidoredu...
1186
Predicted Essential
Community Requests
1B0P
53.7%
Campylobacter jejuni
IDP04036
(
show subtarget assignments
)
1
cloned
CPF_1970
110800938
smc
chromosome segregation protein SMC [Clos...
1185
conserved gene; putative drug target function;
Phase 4: April 2009
3AUX
8.2%
Clostridium perfringens
Cellular processes
Cell division
IDP91694
(
show subtarget assignments
)
8
selected
NP_001989
51873055
FBLN2
fibulin-2 isoform b precursor [Homo sapi...
1184
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1N7D
8.7%
Homo sapiens
IDP04728
(
show subtarget assignments
)
1
selected
BAS0102
49183136
DNA-directed RNA polymerase subunit beta...
1177
Proposed to be essential proteins
Phase 4: April 2009
1HQM
49.2%
Bacillus anthracis
IDP04291
(
show subtarget assignments
)
1
expressed
YPO3603
115349224
putative exported protein [Yersinia pest...
1177
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Unclassified
Role category not yet assigned
IDP04495
(
show subtarget assignments
)
1
soluble
VC0622
15640642
sensory box sensor histidine kinase/resp...
1177
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3A0R
6.6%
Vibrio cholerae
Regulatory functions
Other
IDP90818
(
show subtarget assignments
)
8
expressed
YPO1059
16121359
dnaE
DNA polymerase III subunit alpha [Yersin...
1171
Predicted Essential
Community Requests
2HQA
70%
Yersinia pestis
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
Filter Columns
Filter Columns:
Target Id
Locus Tag
Priority
Stage
Ncbi Gi
Gene Name
Common Name
Length
Justification
Project
Homolog Pdb Id
Homolog Sequence Identity
Organism
Tigr Main Role
Tigr Sub Role
