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Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
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cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
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CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP01705
(
show subtarget assignments
)
1
in_pdb
3N5M
BAS1519
49184534
aminotransferase [Bacillus anthracis str...
449
CONSERVED GENE/PATHWAY
Phase 3: June 2008
3N5M
99.6%
Bacillus anthracis
N/A
N/A
IDP04624
(
show subtarget assignments
)
1
in_pdb
3B2B
3UWD
BAS4988
49187974
phosphoglycerate kinase [Bacillus anthra...
394
Proposed to be essential proteins
Phase 4: April 2009
3B2B
99.7%
Bacillus anthracis
IDP05333
(
show subtarget assignments
)
1
cloned
BAS2031
49185042
-
aspartyl-tRNA synthetase [Bacillus anthr...
432
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1N9W
49.5%
Bacillus anthracis
Protein synthesis: tRNA aminoacylation
IDP05315
(
show subtarget assignments
)
1
cloned
BAS0383
49183411
-
cell wall anchor domain-containing prote...
267
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3HQV
23.6%
Bacillus anthracis
Cell envelope: Other
IDP05335
(
show subtarget assignments
)
1
expressed
BAS2222
49185231
-
threonyl-tRNA synthetase [Bacillus anthr...
639
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1NYQ
50.5%
Bacillus anthracis
Protein synthesis: tRNA aminoacylation
IDP04625
(
show subtarget assignments
)
1
cloned
BAS5050
49188036
glycosyl transferase, group 4 family pro...
357
Proposed to be essential proteins
Phase 4: April 2009
Bacillus anthracis
IDP04620
(
show subtarget assignments
)
1
cloned
BAS4482
49187477
DNA polymerase I [Bacillus anthracis str...
891
Proposed to be essential proteins
Phase 4: April 2009
3TAN
45%
Bacillus anthracis
IDP04618
(
show subtarget assignments
)
1
cloned
BAS4456
49187451
phenylalanyl-tRNA synthetase subunit alp...
344
Proposed to be essential proteins
Phase 4: April 2009
2RHQ
57.6%
Bacillus anthracis
IDP04626
(
show subtarget assignments
)
1
cloned
BAS5178
49188164
peptide chain release factor 1 [Bacillus...
358
Proposed to be essential proteins
Phase 4: April 2009
1ZBT
59.2%
Bacillus anthracis
IDP90228
(
show subtarget assignments
)
1
in_pdb
3T5P
3S40
BAS4713
49187704
-
Transcription regulator [contains diacyl...
300
Transcription regulator [contains diacylglycerol kinase catalytic domain]; Predi...
January 2009
3S40
100%
Bacillus anthracis
IDP04612
(
show subtarget assignments
)
1
cloned
BAS3764
49186763
phospho-N-acetylmuramoyl-pentapeptide-tr...
324
Proposed to be essential proteins
Phase 4: April 2009
Bacillus anthracis
IDP04613
(
show subtarget assignments
)
1
cloned
BAS3890
49186888
M20/M25/M40 family peptidase [Bacillus a...
376
Proposed to be essential proteins
Phase 4: April 2009
1YSJ
35.6%
Bacillus anthracis
IDP04137
(
show subtarget assignments
)
1
soluble
BAS0134
49183168
50S ribosomal protein L36 [Bacillus anth...
37
Proposed to be essential proteins
Phase 4: April 2009
1DFE
81.1%
Bacillus anthracis
IDP04614
(
show subtarget assignments
)
1
purified
BAS4131
49187128
glycine cleavage system aminomethyltrans...
366
Proposed to be essential proteins
Phase 4: April 2009
1YX2
66.1%
Bacillus anthracis
IDP04611
(
show subtarget assignments
)
1
cloned
BAS3754
49186753
sporulation sigma factor SigG [Bacillus ...
289
Proposed to be essential proteins
Phase 4: April 2009
1L0O
37%
Bacillus anthracis
IDP04619
(
show subtarget assignments
)
1
crystallized
BAS4478
49187473
glyceraldehyde-3-phosphate dehydrogenase...
342
Proposed to be essential proteins
Phase 4: April 2009
1GD1
58.8%
Bacillus anthracis
IDP04609
(
show subtarget assignments
)
1
soluble
BAS3712
49186711
ribosome-associated GTPase [Bacillus ant...
293
Proposed to be essential proteins
Phase 4: April 2009
1T9H
63.4%
Bacillus anthracis
IDP04135
(
show subtarget assignments
)
1
cloned
BAS4470
49187465
50S ribosomal protein L35 [Bacillus anth...
66
Proposed to be essential proteins
Phase 4: April 2009
1VS6
48.5%
Bacillus anthracis
IDP04608
(
show subtarget assignments
)
1
soluble
BAS3704
49186703
putative glycerol-3-phosphate acyltransf...
330
Proposed to be essential proteins
Phase 4: April 2009
1VI1
66.4%
Bacillus anthracis
IDP04615
(
show subtarget assignments
)
1
cloned
BAS4297
49187293
aspartyl-tRNA synthetase [Bacillus anthr...
591
Proposed to be essential proteins
Phase 4: April 2009
1EQR
52.7%
Bacillus anthracis
IDP04621
(
show subtarget assignments
)
1
cloned
BAS4494
49187489
acetyl-CoA carboxylase carboxyltransfera...
324
Proposed to be essential proteins
Phase 4: April 2009
2F9I
60.2%
Bacillus anthracis
IDP04120
(
show subtarget assignments
)
1
soluble
BAS1475
49184492
xanthine phosphoribosyltransferase [Baci...
197
Proposed to be essential proteins
Phase 4: April 2009
1Y0B
65%
Bacillus anthracis
IDP04119
(
show subtarget assignments
)
1
purified
BAS0131
49183165
adenylate kinase [Bacillus anthracis str...
216
Proposed to be essential proteins
Phase 4: April 2009
1ZIN
74.1%
Bacillus anthracis
IDP04106
(
show subtarget assignments
)
1
cloned
BAS0124
49183158
30S ribosomal protein S8 [Bacillus anthr...
132
Proposed to be essential proteins
Phase 4: April 2009
1SEI
85.6%
Bacillus anthracis
IDP04107
(
show subtarget assignments
)
1
purified
BAS0120
49183154
50S ribosomal protein L14 [Bacillus anth...
122
Proposed to be essential proteins
Phase 4: April 2009
1C04
86.9%
Bacillus anthracis
IDP04610
(
show subtarget assignments
)
1
in_pdb
3RFO
BAS3717
49186716
methionyl-tRNA formyltransferase [Bacill...
314
Proposed to be essential proteins
Phase 4: April 2009
3RFO
100%
Bacillus anthracis
IDP05139
(
show subtarget assignments
)
1
soluble
BAS0353
49183381
-
amino acid ABC transporter, solute bindi...
264
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3TQL
30.3%
Bacillus anthracis
Transport and binding proteins: Unknown substrate
IDP04081
(
show subtarget assignments
)
1
purified
BAS0361
49183389
DNA topoisomerase III [Bacillus anthraci...
729
Proposed to be essential proteins
Phase 4: April 2009
1D6M
27.7%
Bacillus anthracis
IDP04604
(
show subtarget assignments
)
1
cloned
BAS3678
49186677
30S ribosomal protein S2 [Bacillus anthr...
233
Proposed to be essential proteins
Phase 4: April 2009
1FJG
56.2%
Bacillus anthracis
IDP04605
(
show subtarget assignments
)
1
purified
BAS3689
49186688
ribosomal biogenesis GTPase [Bacillus an...
296
Proposed to be essential proteins
Phase 4: April 2009
1PUJ
67.2%
Bacillus anthracis
IDP05572
(
show subtarget assignments
)
1
cloned
BAS4090
49187088
-
stage III sporulation protein AH [Bacill...
223
essential/virulence/pathogenesis /
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP04606
(
show subtarget assignments
)
1
cloned
BAS3692
49186691
tRNA (guanine-N(1)-)-methyltransferase [...
244
Proposed to be essential proteins
Phase 4: April 2009
3KY7
62.3%
Bacillus anthracis
IDP04080
(
show subtarget assignments
)
1
cloned
BAS0123
49183157
30S ribosomal protein S14 [Bacillus anth...
61
Proposed to be essential proteins
Phase 4: April 2009
1FJG
73.8%
Bacillus anthracis
IDP04616
(
show subtarget assignments
)
1
purified
BAS4313
49187308
S-adenosylmethionine:tRNA ribosyltransfe...
350
Proposed to be essential proteins
Phase 4: April 2009
1YY3
71.4%
Bacillus anthracis
IDP05573
(
show subtarget assignments
)
1
selected
BAS4798
49187788
-
cell surface protein, anchor [Bacillus a...
2025
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
DNA metabolism: DNA replication, recombination, and repair
IDP04074
(
show subtarget assignments
)
1
cloned
BAS4469
49187464
50S ribosomal protein L20 [Bacillus anth...
118
Proposed to be essential proteins
Phase 4: April 2009
1VS6
55.1%
Bacillus anthracis
IDP04071
(
show subtarget assignments
)
1
cloned
BAS0129
49183163
50S ribosomal protein L15 [Bacillus anth...
146
Proposed to be essential proteins
Phase 4: April 2009
1VSA
51.4%
Bacillus anthracis
IDP04079
(
show subtarget assignments
)
1
purified
BAS0100
49183134
50S ribosomal protein L7/L12 [Bacillus a...
119
Proposed to be essential proteins
Phase 4: April 2009
1DD3
63.3%
Bacillus anthracis
IDP04607
(
show subtarget assignments
)
1
cloned
BAS3700
49186699
ribonuclease III [Bacillus anthracis str...
245
Proposed to be essential proteins
Phase 4: April 2009
1O0W
40%
Bacillus anthracis
IDP04069
(
show subtarget assignments
)
1
in_pdb
3R3T
BAS5327
49188311
30S ribosomal protein S6 [Bacillus anthr...
96
Proposed to be essential proteins
Phase 4: April 2009
3R3T
100%
Bacillus anthracis
IDP04057
(
show subtarget assignments
)
1
purified
BAS0125
49183159
50S ribosomal protein L6 [Bacillus anthr...
179
Proposed to be essential proteins
Phase 4: April 2009
1C04
74.9%
Bacillus anthracis
IDP04600
(
show subtarget assignments
)
1
cloned
BAS2547
49185555
preprotein translocase subunit SecY [Bac...
434
Proposed to be essential proteins
Phase 4: April 2009
3DIN
42.2%
Bacillus anthracis
IDP04601
(
show subtarget assignments
)
1
in_pdb
3RHI
BAS3574
49186575
DNA-binding protein HU [Bacillus anthrac...
90
Proposed to be essential proteins
Phase 4: April 2009
3RHI
100%
Bacillus anthracis
IDP04064
(
show subtarget assignments
)
1
expressed
BAS0127
49183161
30S ribosomal protein S5 [Bacillus anthr...
166
Proposed to be essential proteins
Phase 4: April 2009
1PKP
75.3%
Bacillus anthracis
IDP05569
(
show subtarget assignments
)
1
soluble
BAS4454
49187449
-
asparaginyl-tRNA synthetase [Bacillus an...
463
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1X54
35.9%
Bacillus anthracis
Protein synthesis: tRNA aminoacylation
IDP04034
(
show subtarget assignments
)
1
purified
BAS0128
49183162
50S ribosomal protein L30 [Bacillus anth...
60
Proposed to be essential proteins
Phase 4: April 2009
1VS6
53.3%
Bacillus anthracis
IDP04035
(
show subtarget assignments
)
1
in_pdb
3P0R
BAS5262
49188247
azoreductase [Bacillus anthracis str. St...
208
Proposed to be essential proteins
Phase 4: April 2009
3P0R
100%
Bacillus anthracis
IDP04598
(
show subtarget assignments
)
1
cloned
BAS1442
49184459
dihydrodipicolinate reductase [Bacillus ...
266
Proposed to be essential proteins
Phase 4: April 2009
1C3V
40.6%
Bacillus anthracis
IDP04028
(
show subtarget assignments
)
1
soluble
BAS0109
49183143
30S ribosomal protein S10 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1P6G
61.8%
Bacillus anthracis
IDP04021
(
show subtarget assignments
)
1
expressed
BAS3695
49186694
30S ribosomal protein S16 [Bacillus anth...
90
Proposed to be essential proteins
Phase 4: April 2009
1EMW
42.2%
Bacillus anthracis
IDP04022
(
show subtarget assignments
)
1
cloned
BAS0095
49183129
preprotein translocase subunit SecE [Bac...
59
Proposed to be essential proteins
Phase 4: April 2009
3DIN
33.9%
Bacillus anthracis
IDP04024
(
show subtarget assignments
)
1
cloned
BAS5319
49188303
DNA-binding response regulator YycF [Bac...
235
Proposed to be essential proteins
Phase 4: April 2009
2OQR
47.7%
Bacillus anthracis
IDP04602
(
show subtarget assignments
)
1
purified
BAS3667
49186666
transcription elongation factor NusA [Ba...
368
Proposed to be essential proteins
Phase 4: April 2009
1HH2
44%
Bacillus anthracis
IDP04027
(
show subtarget assignments
)
1
cloned
BAS4637
49187628
leucyl-tRNA synthetase [Bacillus anthrac...
802
Proposed to be essential proteins
Phase 4: April 2009
1H3N
45.9%
Bacillus anthracis
IDP04599
(
show subtarget assignments
)
1
cloned
BAS2268
49185277
aspartate-semialdehyde dehydrogenase [Ba...
347
Proposed to be essential proteins
Phase 4: April 2009
2GYY
55.3%
Bacillus anthracis
IDP05570
(
show subtarget assignments
)
1
expressed
BAS5100
49188086
-
hypothetical protein BAS5100 [Bacillus a...
132
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP04596
(
show subtarget assignments
)
1
purified
BAS1099
49184119
tryptophanyl-tRNA synthetase [Bacillus a...
329
Proposed to be essential proteins
Phase 4: April 2009
3PRH
73.9%
Bacillus anthracis
IDP04067
(
show subtarget assignments
)
1
purified
BAS4417
49187412
thioredoxin [Bacillus anthracis str. Ste...
104
Proposed to be essential proteins
Phase 4: April 2009
2GZY
75%
Bacillus anthracis
IDP04603
(
show subtarget assignments
)
1
purified
BAS3670
49186669
prolyl-tRNA synthetase [Bacillus anthrac...
566
Proposed to be essential proteins
Phase 4: April 2009
2J3L
58.1%
Bacillus anthracis
IDP04617
(
show subtarget assignments
)
1
expressed
BAS4342
49187337
50S ribosomal protein L21 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1VSA
54.9%
Bacillus anthracis
IDP05249
(
show subtarget assignments
)
1
soluble
BAS2289
49185298
-
hypothetical protein BAS2289 [Bacillus a...
512
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP04597
(
show subtarget assignments
)
1
expressed
BAS1384
49184401
resB protein [Bacillus anthracis str. St...
541
Proposed to be essential proteins
Phase 4: April 2009
Bacillus anthracis
IDP05560
(
show subtarget assignments
)
1
soluble
BAS2951
49185956
-
hypothetical protein BAS2951 [Bacillus a...
133
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP90943
(
show subtarget assignments
)
8
purified
BAS0032
49183067
DNA replication intiation control protei...
121
This is an essential protein that connects DNA replication to cell growth by bin...
Community Requests
Bacillus anthracis
IDP04590
(
show subtarget assignments
)
1
expressed
BAS0136
49183170
30S ribosomal protein S11 [Bacillus anth...
129
Proposed to be essential proteins
Phase 4: April 2009
1VS5
65.9%
Bacillus anthracis
IDP04589
(
show subtarget assignments
)
1
expressed
BAS0135
49183169
30S ribosomal protein S13 [Bacillus anth...
121
Proposed to be essential proteins
Phase 4: April 2009
1FJG
63.9%
Bacillus anthracis
IDP04585
(
show subtarget assignments
)
1
purified
BAS0116
49183150
30S ribosomal protein S3 [Bacillus anthr...
219
Proposed to be essential proteins
Phase 4: April 2009
1VS5
54.3%
Bacillus anthracis
IDP04586
(
show subtarget assignments
)
1
cloned
BAS0117
49183151
50S ribosomal protein L16 [Bacillus anth...
144
Proposed to be essential proteins
Phase 4: April 2009
1VSA
60.4%
Bacillus anthracis
IDP04591
(
show subtarget assignments
)
1
cloned
BAS0138
49183172
50S ribosomal protein L17 [Bacillus anth...
120
Proposed to be essential proteins
Phase 4: April 2009
1NKW
50.8%
Bacillus anthracis
IDP04587
(
show subtarget assignments
)
1
purified
BAS0118
49183152
50S ribosomal protein L29 [Bacillus anth...
66
Proposed to be essential proteins
Phase 4: April 2009
1R73
45.5%
Bacillus anthracis
IDP04003
(
show subtarget assignments
)
1
cloned
BAS0126
49183160
50S ribosomal protein L18 [Bacillus anth...
120
Proposed to be essential proteins
Phase 4: April 2009
1OVY
75.8%
Bacillus anthracis
IDP04584
(
show subtarget assignments
)
1
purified
BAS0112
49183146
50S ribosomal protein L23 [Bacillus anth...
96
Proposed to be essential proteins
Phase 4: April 2009
1N88
43.8%
Bacillus anthracis
IDP04588
(
show subtarget assignments
)
1
cloned
BAS0130
49183164
preprotein translocase subunit SecY [Bac...
433
Proposed to be essential proteins
Phase 4: April 2009
3DIN
43.8%
Bacillus anthracis
IDP04579
(
show subtarget assignments
)
1
cloned
BAS0098
49183132
50S ribosomal protein L1 [Bacillus anthr...
230
Proposed to be essential proteins
Phase 4: April 2009
3QOY
56.3%
Bacillus anthracis
IDP04580
(
show subtarget assignments
)
1
cloned
BAS0103
49183137
DNA-directed RNA polymerase subunit beta...
1203
Proposed to be essential proteins
Phase 4: April 2009
2GHO
53.6%
Bacillus anthracis
IDP04578
(
show subtarget assignments
)
1
cloned
BAS0089
49183123
cysteinyl-tRNA synthetase [Bacillus anth...
465
Proposed to be essential proteins
Phase 4: April 2009
1LI5
45.6%
Bacillus anthracis
IDP04581
(
show subtarget assignments
)
1
purified
BAS0108
49183142
elongation factor Tu [Bacillus anthracis...
395
Proposed to be essential proteins
Phase 4: April 2009
1DG1
75.2%
Bacillus anthracis
IDP04582
(
show subtarget assignments
)
1
purified
BAS0110
49183144
50S ribosomal protein L3 [Bacillus anthr...
210
Proposed to be essential proteins
Phase 4: April 2009
1NKW
53.3%
Bacillus anthracis
IDP04576
(
show subtarget assignments
)
1
purified
BAS0076
49183111
lysyl-tRNA synthetase [Bacillus anthraci...
499
Proposed to be essential proteins
Phase 4: April 2009
3A74
77.6%
Bacillus anthracis
IDP04577
(
show subtarget assignments
)
1
cloned
BAS0087
49183121
glutamyl-tRNA synthetase [Bacillus anthr...
485
Proposed to be essential proteins
Phase 4: April 2009
2O5R
44.4%
Bacillus anthracis
IDP04583
(
show subtarget assignments
)
1
cloned
BAS0111
49183145
50S ribosomal protein L4 [Bacillus anthr...
207
Proposed to be essential proteins
Phase 4: April 2009
1DMG
47.1%
Bacillus anthracis
IDP04592
(
show subtarget assignments
)
1
expressed
BAS0143
49183177
50S ribosomal protein L13 [Bacillus anth...
145
Proposed to be essential proteins
Phase 4: April 2009
1P85
56.6%
Bacillus anthracis
IDP04572
(
show subtarget assignments
)
1
soluble
BAS0005
49183044
DNA gyrase subunit B [Bacillus anthracis...
640
Proposed to be essential proteins
Phase 4: April 2009
1EI1
34.4%
Bacillus anthracis
IDP04573
(
show subtarget assignments
)
1
purified
BAS0006
49183045
DNA gyrase subunit A [Bacillus anthracis...
823
Proposed to be essential proteins
Phase 4: April 2009
2XCO
42.9%
Bacillus anthracis
IDP04571
(
show subtarget assignments
)
1
cloned
BAS0002
49183041
DNA polymerase III subunit beta [Bacillu...
379
Proposed to be essential proteins
Phase 4: April 2009
2AWA
42%
Bacillus anthracis
IDP04574
(
show subtarget assignments
)
1
soluble
BAS0015
49183051
seryl-tRNA synthetase [Bacillus anthraci...
424
Proposed to be essential proteins
Phase 4: April 2009
2DQ3
57.8%
Bacillus anthracis
IDP05452
(
show subtarget assignments
)
1
cloned
BAS5207
49188193
-
collagen adhesion protein, C-terminal [B...
882
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3KPT
12.6%
Bacillus anthracis
Protein fate: Degradation of proteins, peptides, and glycopeptides
IDP05025
(
show subtarget assignments
)
1
cloned
BAS4742
49187733
-
hypothetical protein BAS4742 [Bacillus a...
200
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP05453
(
show subtarget assignments
)
1
purified
BAS5213
49188199
-
arginyl-tRNA synthetase [Bacillus anthra...
556
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
3FNR
31.8%
Bacillus anthracis
Protein synthesis: tRNA aminoacylation
IDP05023
(
show subtarget assignments
)
1
expressed
BAS2353
49185362
-
hemolysin II, C-terminal [Bacillus anthr...
240
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3ANZ
27.9%
Bacillus anthracis
Cellular processes: Pathogenesis
IDP05024
(
show subtarget assignments
)
1
soluble
BAS4675
49187666
-
ABC transporter, substrate-binding prote...
325
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3IX1
20.6%
Bacillus anthracis
Unclassified: Role category not yet assigned
IDP04575
(
show subtarget assignments
)
1
cloned
BAS0037
49183072
methionyl-tRNA synthetase [Bacillus anth...
660
Proposed to be essential proteins
Phase 4: April 2009
2CSX
35.3%
Bacillus anthracis
IDP04593
(
show subtarget assignments
)
1
cloned
BAS0144
49183178
30S ribosomal protein S9 [Bacillus anthr...
130
Proposed to be essential proteins
Phase 4: April 2009
1VS5
55.4%
Bacillus anthracis
IDP04005
(
show subtarget assignments
)
1
purified
BAS4355
49187350
valyl-tRNA synthetase [Bacillus anthraci...
881
Proposed to be essential proteins
Phase 4: April 2009
1GAX
42.6%
Bacillus anthracis
IDP05421
(
show subtarget assignments
)
1
soluble
BAS1418
49184435
-
hypothetical protein BAS1418 [Bacillus a...
237
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP04416
(
show subtarget assignments
)
1
purified
BAS4049
49187047
ribonuclease Z [Bacillus anthracis str. ...
307
Proposed to be essential proteins
Phase 4: April 2009
1Y44
61.2%
Bacillus anthracis
IDP04396
(
show subtarget assignments
)
1
purified
BAS4797
49187787
pyridine nucleotide-disulphide oxidoredu...
331
Proposed to be essential proteins
Phase 4: April 2009
3LZW
76.7%
Bacillus anthracis
IDP04728
(
show subtarget assignments
)
1
selected
BAS0102
49183136
DNA-directed RNA polymerase subunit beta...
1177
Proposed to be essential proteins
Phase 4: April 2009
1HQM
49.2%
Bacillus anthracis
IDP04730
(
show subtarget assignments
)
1
cloned
BAS4284
49187280
alanyl-tRNA synthetase [Bacillus anthrac...
880
Proposed to be essential proteins
Phase 4: April 2009
1RIQ
26.3%
Bacillus anthracis
IDP04731
(
show subtarget assignments
)
1
purified
BAS3675
49186674
ribosome recycling factor [Bacillus anth...
185
Proposed to be essential proteins
Phase 4: April 2009
1IS1
50.8%
Bacillus anthracis
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