Center for Structural Genomics of Infectious Diseases


CSGID ID	Priority	stage	Locus Tag	NCBI GI	Gene Name	Common Name	Sequence Length	Justification	Selection Phase	Homolog PDB ID	Homolog Sequence Identity	Target Organism	TIGR Main Role	TIGR Subrole	Request Person
IDP00520 (show subtarget assignments)	1	in_pdb 3F6M 3FPI	YPO3360	16123510	ispF	2-C-methyl-D-erythritol 2,4-cyclodiphosp...	162	Conserved Gene / Pathway	Phase 2: March 2008	3F6M	100%	Yersinia pestis	Biosynthesis of cofactors, prosthetic groups, and carriers	Other

IDP00519 (show subtarget assignments)	1	cloned	YPO3446	16123594	argI	ornithine carbamoyltransferase subunit I...	335	Conserved Gene / Pathway	Phase 2: March 2008	1AKM	79.1%	Yersinia pestis	Amino acid biosynthesis	Glutamate family

IDP00981 (show subtarget assignments)	1	purified	STM2052	16765382	pduQ	propanol dehydrogenase	370	Conserved Gene / Pathway	Phase 2: March 2008	3OWO	35.3%	Salmonella enterica	Energy metabolism	Fermentation

IDP00980 (show subtarget assignments)	1	purified	STM1970	16765308	fliG	flagellar motor switch protein G	331	Conserved Gene / Pathway	Phase 2: March 2008	3HJL	28.7%	Salmonella enterica	Cellular processes	Chemotaxis and motility

IDP00979 (show subtarget assignments)	1	purified	STM1953	16765291	yedO	D-cysteine desulfhydrase	328	Conserved Gene / Pathway	Phase 2: March 2008	1J0A	38.7%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Pyridoxine

IDP00978 (show subtarget assignments)	1	purified	STM1951	16765289	yecC	putative amino-acid ABC transporter ATP-...	250	Conserved Gene / Pathway	Phase 2: March 2008	2OLJ	54.8%	Salmonella enterica	Transport and binding proteins	Amino acids, peptides and amines

IDP00977 (show subtarget assignments)	1	expressed	STM1932	16765273	ftnB	ferritin-like protein	167	Conserved Gene / Pathway	Phase 2: March 2008	1EUM	33.5%	Salmonella enterica	Transport and binding proteins	Cations and iron carrying compounds

IDP00517 (show subtarget assignments)	1	soluble	YPMT1.71	16082863		hypothetical protein YPMT1.71	328	Conserved Gene / Pathway	Phase 2: March 2008			Yersinia pestis	Cellular processes	Cell division

IDP00516 (show subtarget assignments)	1	soluble	YPO4022	16124145		putative iron transport protein	317	Conserved Gene / Pathway	Phase 2: March 2008	3GFV	34.4%	Yersinia pestis	Transport and binding proteins	Unknown substrate

IDP00975 (show subtarget assignments)	1	cloned	STM1815	16765156	minD	cell division inhibitor MinD	270	Conserved Gene / Pathway	Phase 2: March 2008	3Q9L	93.3%	Salmonella enterica	Cellular processes	Cell division

IDP00973 (show subtarget assignments)	1	purified	STM1756	16765100	purU	formyltetrahydrofolate deformylase	280	Conserved Gene / Pathway	Phase 2: March 2008	3O1L	42.7%	Salmonella enterica	Purines, pyrimidines, nucleosides, and nucleotides	Purine ribonucleotide biosynthesis

IDP00972 (show subtarget assignments)	1	expressed	STM1743	16765087	oppD	oligopeptide transporter ATP-binding com...	335	Conserved Gene / Pathway	Phase 2: March 2008	1Z47	25.7%	Salmonella enterica	Transport and binding proteins	Amino acids, peptides and amines

IDP00971 (show subtarget assignments)	1	in_pdb 3IAH	STM1717	16765061	yciK	short chain dehydrogenase	253	Conserved Gene / Pathway	Phase 2: March 2008	3IAH	100%	Salmonella enterica	Central intermediary metabolism	Other

IDP00514 (show subtarget assignments)	1	selected	YPO3721	16123859		hemolysin	1635	Conserved Gene / Pathway	Phase 2: March 2008	3FY3	9%	Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00970 (show subtarget assignments)	1	soluble	STM1682	16765025	tpx	thiol peroxidase	168	Conserved Gene / Pathway	Phase 2: March 2008	1QXH	87.5%	Salmonella enterica	Cellular processes	Detoxification

IDP00969 (show subtarget assignments)	1	purified	STM1597	161353598	ydcW	putative aldehyde dehydrogenase	474	Conserved Gene / Pathway	Phase 2: March 2008	1WNB	83.5%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Other

IDP00513 (show subtarget assignments)	1	cloned	YPO3674	16123817		putative insecticidal toxin	1011	Conserved Gene / Pathway	Phase 2: March 2008			Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00512 (show subtarget assignments)	1	cloned	YPO2244	16122472		electron transport complex protein RnfC ...	620	Conserved Gene / Pathway	Phase 2: March 2008			Yersinia pestis	Unclassified	Role category not yet assigned

IDP00511 (show subtarget assignments)	1	in_pdb 3RPE	YPO0670	16120995	mdaB	putative modulator of drug activity	194	Conserved Gene / Pathway	Phase 2: March 2008	3RPE	100%	Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00965 (show subtarget assignments)	1	purified	STM1463	16764811	add	adenosine deaminase	333	Conserved Gene / Pathway	Phase 2: March 2008	1NDV	33.8%	Salmonella enterica	Purines, pyrimidines, nucleosides, and nucleotides	Salvage of nucleosides and nucleotides

IDP00964 (show subtarget assignments)	0	work_stopped	STM1439	16764787	ydhF	putative aldo/keto reductase	298	Conserved Gene / Pathway	Phase 2: March 2008	1OG6	88.9%	Salmonella enterica	Unknown function	General

IDP00963 (show subtarget assignments)	1	purified	STM1436	16764784	nemA	N-ethylmaleimide reductase, FMN-linked	365	Conserved Gene / Pathway	Phase 2: March 2008	3P62	87.4%	Salmonella enterica	Central intermediary metabolism	Other

IDP00509 (show subtarget assignments)	1	in_pdb 3RY3	YPO2660	16122866		putative solute-binding protein	525	Conserved Gene / Pathway	Phase 2: March 2008	3RY3	100%	Yersinia pestis	Transport and binding proteins	Unknown substrate

IDP00961 (show subtarget assignments)	1	expressed	STM1385	16764735	ttrB	tetrathionate reductase complex subunit ...	250	Conserved Gene / Pathway	Phase 2: March 2008	2VPW	34.4%	Salmonella enterica	Energy metabolism	Electron transport

IDP00508 (show subtarget assignments)	1	expressed	YPO1315	16121597		putative hydrolase	216	Conserved Gene / Pathway	Phase 2: March 2008	3FVV	35.2%	Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00959 (show subtarget assignments)	1	soluble	STM1303	16764654	argD	bifunctional succinylornithine transamin...	408	Conserved Gene / Pathway	Phase 2: March 2008	2PB0	60.8%	Salmonella enterica	Amino acid biosynthesis	Glutamate family

IDP00958 (show subtarget assignments)	1	soluble	STM1218	16764573	lolD	lipoprotein transporter ATP-binding subu...	233	Conserved Gene / Pathway	Phase 2: March 2008	2PCJ	43.3%	Salmonella enterica	Transport and binding proteins	Unknown substrate

IDP00957 (show subtarget assignments)	0	work_stopped	STM1202	16764557	ycfH	predicted metallodependent hydrolase	265	Conserved Gene / Pathway	Phase 2: March 2008	1YIX	92.8%	Salmonella enterica	Unknown function	Enzymes of unknown specificity

IDP00506 (show subtarget assignments)	1	expressed	YPO2491	16122712		putative hemolysin activator protein	562	Conserved Gene / Pathway	Phase 2: March 2008	2QDZ	21.9%	Yersinia pestis	Protein fate	Protein and peptide secretion and trafficking

IDP00955 (show subtarget assignments)	1	cloned	STM1192	16764547	plsX	fatty acid/phospholipid synthesis protei...	359	Conserved Gene / Pathway	Phase 2: March 2008	1U7N	36.5%	Salmonella enterica	Fatty acid and phospholipid metabolism	Biosynthesis

IDP00505 (show subtarget assignments)	1	purified	YPO1298	16121580	fruB	fructose-specific PTS IIA/HPr components...	377	Conserved Gene / Pathway	Phase 2: March 2008	1A3A	17%	Yersinia pestis	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP00953 (show subtarget assignments)	1	purified	STM1183	16764539	flgK	flagellar hook-associated protein FlgK	553	Conserved Gene / Pathway	Phase 2: March 2008	2D4Y	83.5%	Salmonella enterica	Cellular processes	Toxin production and resistance

IDP00952 (show subtarget assignments)	1	soluble	STM1176	16764532	flgD	flagellar basal body rod modification pr...	232	Conserved Gene / Pathway	Phase 2: March 2008	3C12	19.8%	Salmonella enterica	Cell envelope	Surface structures

IDP00951 (show subtarget assignments)	1	in_pdb 3PP8 3KBO	STM1135	16764491	ycdW	putative oxidoreductase	312	Conserved Gene / Pathway	Phase 2: March 2008	3KBO	100%	Salmonella enterica	Central intermediary metabolism	Other

IDP00950 (show subtarget assignments)	1	soluble	STM1119	16764477	wraB	TrpR binding protein WrbA	198	Conserved Gene / Pathway	Phase 2: March 2008	2R96	94.4%	Salmonella enterica	Amino acid biosynthesis	Aromatic amino acid family

IDP00949 (show subtarget assignments)	1	soluble	STM1102	16764460	hpaE	4-hydroxyphenylacetate catabolism	488	Conserved Gene / Pathway	Phase 2: March 2008	2D4E	47.7%	Salmonella enterica	Central intermediary metabolism	Other

IDP00948 (show subtarget assignments)	1	expressed	STM1060	16764419		putative iron-sulfur protein	369	Conserved Gene / Pathway	Phase 2: March 2008	1ROE	8.4%	Salmonella enterica	Energy metabolism	Electron transport

IDP00502 (show subtarget assignments)	1	selected	YPO2045	16122284		putative hemolysin	1576	Conserved Gene / Pathway	Phase 2: March 2008	3FY3	5.6%	Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00946 (show subtarget assignments)	1	expressed	STM0978	16764338	aroA	3-phosphoshikimate 1-carboxyvinyltransfe...	427	Conserved Gene / Pathway	Phase 2: March 2008	1G6S	89.5%	Salmonella enterica	Amino acid biosynthesis	Aromatic amino acid family

IDP00945 (show subtarget assignments)	0	work_stopped	STM0977	16764337	serC	phosphoserine aminotransferase	362	Conserved Gene / Pathway	Phase 2: March 2008	3QM2	100%	Salmonella enterica	Amino acid biosynthesis	Serine family

IDP00501 (show subtarget assignments)	1	purified	YPO0922	16121227	epd	D-erythrose 4-phosphate dehydrogenase	338	Conserved Gene / Pathway	Phase 2: March 2008	2X5J	82.5%	Yersinia pestis	Biosynthesis of cofactors, prosthetic groups, and carriers	Pyridoxine

IDP00944 (show subtarget assignments)	1	crystallized	STM0891	16764252	artP	arginine transporter ATP-binding subunit...	242	Conserved Gene / Pathway	Phase 2: March 2008	1B0U	43.8%	Salmonella enterica	Transport and binding proteins	Amino acids, peptides and amines

IDP00943 (show subtarget assignments)	1	crystallized	STM0862	16764224	yliJ	putative glutathione S-transferase	208	Conserved Gene / Pathway	Phase 2: March 2008	1AW9	28.8%	Salmonella enterica	Cellular processes	Detoxification

IDP00500 (show subtarget assignments)	1	purified	YPO1784	16122038		putative copper resistance protein	128	Conserved Gene / Pathway	Phase 2: March 2008	1IX2	31.2%	Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00499 (show subtarget assignments)	1	in_pdb 3IIE	YPO1048	16121348	dxr	1-deoxy-D-xylulose 5-phosphate reductois...	398	Conserved Gene / Pathway	Phase 2: March 2008	3IIE	100%	Yersinia pestis	Biosynthesis of cofactors, prosthetic groups, and carriers	Other

IDP00941 (show subtarget assignments)	1	purified	STM0846	16764208	moeA	molybdopterin biosynthesis protein MoeA ...	413	Conserved Gene / Pathway	Phase 2: March 2008	1FC5	87.2%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Molybdopterin

IDP00940 (show subtarget assignments)	1	soluble	STM0845	16764207	moeB	molybdopterin biosynthesis protein MoeB ...	249	Conserved Gene / Pathway	Phase 2: March 2008	1JW9	88.8%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Molybdopterin

IDP00939 (show subtarget assignments)	1	expressed	STM0828	16764190	glnQ	glutamine ABC transporter ATP-binding pr...	240	Conserved Gene / Pathway	Phase 2: March 2008	2OLJ	55%	Salmonella enterica	Transport and binding proteins	Amino acids, peptides and amines

IDP00937 (show subtarget assignments)	1	cloned	STM0795	16764158	bioF	8-amino-7-oxononanoate synthase	385	Conserved Gene / Pathway	Phase 2: March 2008	1BS0	80%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Biotin

IDP00936 (show subtarget assignments)	1	soluble	STM0793	16764156	bioA	adenosylmethionine--8-amino-7-oxononanoa...	429	Conserved Gene / Pathway	Phase 2: March 2008	1MLY	86.2%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Biotin

IDP00935 (show subtarget assignments)	1	soluble	STM0783	16764147	modC	molybdate transporter ATP-binding protei...	352	Conserved Gene / Pathway	Phase 2: March 2008	3D31	29.5%	Salmonella enterica	Transport and binding proteins	Anions

IDP00934 (show subtarget assignments)	0	work_stopped	STM0779	16764143	modE	DNA-binding transcriptional dual regulat...	262	Conserved Gene / Pathway	Phase 2: March 2008	1B9M	89.3%	Salmonella enterica	Transport and binding proteins	Anions

IDP00933 (show subtarget assignments)	1	soluble	STM0662	16764039	gltL	glutamate/aspartate transporter	241	Conserved Gene / Pathway	Phase 2: March 2008	2OLJ	54.4%	Salmonella enterica	Transport and binding proteins	Amino acids, peptides and amines

IDP00932 (show subtarget assignments)	1	purified	STM0645	16764022	nadD	nicotinic acid mononucleotide adenyltran...	213	Conserved Gene / Pathway	Phase 2: March 2008	1K4K	85.4%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Pyridine nucleotides

IDP00930 (show subtarget assignments)	1	expressed	STM0612	16763989		putative hydrogenase protein	185	Conserved Gene / Pathway	Phase 2: March 2008	2VPW	30.3%	Salmonella enterica	Energy metabolism	Anaerobic

IDP00929 (show subtarget assignments)	1	soluble	STM0603	16763980	ybdL	putative aminotransferase	386	Conserved Gene / Pathway	Phase 2: March 2008	1U08	85.5%	Salmonella enterica	Central intermediary metabolism	Other

IDP00493 (show subtarget assignments)	1	expressed	YPO1124	16121424	tolB	translocation protein TolB	430	Conserved Gene / Pathway	Phase 2: March 2008	1C5K	84.9%	Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00928 (show subtarget assignments)	1	purified	STM0602	16763979	ybdH	putative glycerol dehydrogenase	362	Conserved Gene / Pathway	Phase 2: March 2008	1KQ3	31.1%	Salmonella enterica	Central intermediary metabolism	Other

IDP00927 (show subtarget assignments)	1	soluble	STM0598	16763975	entA	2,3-dihydroxybenzoate-2,3-dehydrogenase ...	251	Conserved Gene / Pathway	Phase 2: March 2008	2FWM	89.2%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Other

IDP00492 (show subtarget assignments)	1	selected	YPO1559	16121830		hypothetical protein YPO1559	379	Conserved Gene / Pathway	Phase 2: March 2008			Yersinia pestis	Cellular processes	Toxin production and resistance

IDP00926 (show subtarget assignments)	1	soluble	STM0597	16763974	entB	2,3-dihydro-2,3-dihydroxybenzoate synthe...	285	Conserved Gene / Pathway	Phase 2: March 2008	2FQ1	88.4%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Other

IDP00491 (show subtarget assignments)	1	purified	YPO1107	16121407		heat shock protein GrpE	192	Conserved Gene / Pathway	Phase 2: March 2008	1DKG	59.4%	Yersinia pestis	Protein fate	Protein folding and stabilization

IDP00924 (show subtarget assignments)	1	purified	STM0590	16763967	fepC	iron-enterobactin transporter ATP-bindin...	264	Conserved Gene / Pathway	Phase 2: March 2008	3GFO	28.4%	Salmonella enterica	Transport and binding proteins	Cations and iron carrying compounds

IDP00923 (show subtarget assignments)	1	in_pdb 3HZN	STM0578	16763955	nfnB	dihydropteridine reductase	217	Conserved Gene / Pathway	Phase 2: March 2008	3HZN	100%	Salmonella enterica	Central intermediary metabolism	Other

IDP00490 (show subtarget assignments)	1	cloned	YPO1537	16121810		putative iron-siderophore receptor	753	Conserved Gene / Pathway	Phase 2: March 2008	3EFM	36%	Yersinia pestis	Transport and binding proteins	Cations and iron carrying compounds

IDP00922 (show subtarget assignments)	1	soluble	STM0533	16763913	purK	phosphoribosylaminoimidazole carboxylase...	355	Conserved Gene / Pathway	Phase 2: March 2008	1B6S	88.2%	Salmonella enterica	Purines, pyrimidines, nucleosides, and nucleotides	Purine ribonucleotide biosynthesis

IDP00921 (show subtarget assignments)	1	purified	STM0507	16763887	ybbA	putative ABC transporter ATP-binding pro...	228	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	42.5%	Salmonella enterica	Transport and binding proteins	Unknown substrate

IDP00489 (show subtarget assignments)	1	soluble	YPO1533	16121806		putative iron-siderophore transport syst...	282	Conserved Gene / Pathway	Phase 2: March 2008	3FVQ	28.4%	Yersinia pestis	Transport and binding proteins	Cations and iron carrying compounds

IDP00920 (show subtarget assignments)	1	purified	STM0417	16763797	ribH	riboflavin synthase subunit beta	156	Conserved Gene / Pathway	Phase 2: March 2008	3MK3	100%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Riboflavin, FMN, and FAD

IDP00919 (show subtarget assignments)	1	in_pdb 3Q1K 3I12	STM0380	16763760	ddl	D-alanyl-alanine synthetase A	364	Conserved Gene / Pathway	Phase 2: March 2008	3I12	100%	Salmonella enterica	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00918 (show subtarget assignments)	1	soluble	STM0372	16763752	hemB	delta-aminolevulinic acid dehydratase	324	Conserved Gene / Pathway	Phase 2: March 2008	1I8J	93.5%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Heme, porphyrin, and cobalamin

IDP00917 (show subtarget assignments)	1	cloned	STM0355	16763735		putative copper chaperone	64	Conserved Gene / Pathway	Phase 2: March 2008	2K2P	39.1%	Salmonella enterica	Transport and binding proteins	Cations and iron carrying compounds

IDP00487 (show subtarget assignments)	1	soluble	YPO1491	16121764		ABC transporter ATP-binding protein	531	Conserved Gene / Pathway	Phase 2: March 2008	3BK7	24.7%	Yersinia pestis	Transport and binding proteins	Unknown substrate

IDP00916 (show subtarget assignments)	0	work_stopped	STM0247	16763636	metN	DL-methionine transporter ATP-binding su...	343	Conserved Gene / Pathway	Phase 2: March 2008	3DHW	95.3%	Salmonella enterica	Transport and binding proteins	Unknown substrate

IDP00486 (show subtarget assignments)	1	expressed	YPO1463	16121738		putative acyl transferase	282	Conserved Gene / Pathway	Phase 2: March 2008	3RGI	47.2%	Yersinia pestis	Fatty acid and phospholipid metabolism	Biosynthesis

IDP00850 (show subtarget assignments)	1	soluble	SACOL2389	57285120		transcriptional regulatory protein DegU,...	217	Conserved Gene / Pathway	Phase 2: March 2008	1A04	31.3%	Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00914 (show subtarget assignments)	1	soluble	STM0220	16763610	dxr	1-deoxy-D-xylulose 5-phosphate reductois...	398	Conserved Gene / Pathway	Phase 2: March 2008	1K5H	88.7%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Other

IDP00913 (show subtarget assignments)	0	work_stopped	STM0219	16763609	frr	ribosome recycling factor	185	Conserved Gene / Pathway	Phase 2: March 2008	1EK8	94.1%	Salmonella enterica	Protein synthesis	Translation factors

IDP00912 (show subtarget assignments)	1	soluble	STM0193	16763583	fhuD	iron-hydroxamate transporter substrate-b...	296	Conserved Gene / Pathway	Phase 2: March 2008	1ESZ	75%	Salmonella enterica	Transport and binding proteins	Cations and iron carrying compounds

IDP00911 (show subtarget assignments)	1	expressed	STM0191	16763581	fhuA	ferrichrome outer membrane transporter	729	Conserved Gene / Pathway	Phase 2: March 2008	2FCP	72.3%	Salmonella enterica	Cell envelope	Other

IDP00484 (show subtarget assignments)	1	cloned	YPO1417	16121697		putative iron-sulfur binding protein	370	Conserved Gene / Pathway	Phase 2: March 2008	2PIA	7%	Yersinia pestis	Energy metabolism	Electron transport

IDP00909 (show subtarget assignments)	0	work_stopped	STM0171	16763561	yadF	carbonic anhydrase	220	Conserved Gene / Pathway	Phase 2: March 2008	3QY1	100%	Salmonella enterica	Central intermediary metabolism	Other

IDP00908 (show subtarget assignments)	1	expressed	STM0143	16763533	hofB	hypothetical protein STM0143	461	Conserved Gene / Pathway	Phase 2: March 2008	1P9R	37.3%	Salmonella enterica	Cell envelope	Surface structures

IDP00907 (show subtarget assignments)	1	purified	STM0140	16763530	coaE	dephospho-CoA kinase	206	Conserved Gene / Pathway	Phase 2: March 2008	1N3B	88.8%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Other

IDP00904 (show subtarget assignments)	0	work_stopped	STM0124	16763514	murF	UDP-N-acetylmuramoyl-tripeptide--D-alany...	452	Conserved Gene / Pathway	Phase 2: March 2008	1GG4	87.6%	Salmonella enterica	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00480 (show subtarget assignments)	1	soluble	YPO3118	16123283	adk	adenylate kinase	214	Conserved Gene / Pathway	Phase 2: March 2008	1AKE	87.4%	Yersinia pestis	Purines, pyrimidines, nucleosides, and nucleotides	Nucleotide and nucleoside interconversions

IDP00902 (show subtarget assignments)	1	expressed	STM0045	16763435	ribF	bifunctional riboflavin kinase/FMN adeny...	312	Conserved Gene / Pathway	Phase 2: March 2008	1MRZ	33%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Riboflavin, FMN, and FAD

IDP00901 (show subtarget assignments)	1	purified	STM0004	16763394	thrC	threonine synthase	428	Conserved Gene / Pathway	Phase 2: March 2008	1VB3	93.5%	Salmonella enterica	Amino acid biosynthesis	Aspartate family

IDP00479 (show subtarget assignments)	1	in_pdb 3H07	YPO0658	16120983	ribB	3,4-dihydroxy-2-butanone 4-phosphate syn...	217	Conserved Gene / Pathway	Phase 2: March 2008	3H07	100%	Yersinia pestis	Biosynthesis of cofactors, prosthetic groups, and carriers	Riboflavin, FMN, and FAD

IDP00900 (show subtarget assignments)	0	work_stopped	STM4247	16767497	alr	alanine racemase	359	Conserved Gene / Pathway	Phase 2: March 2008	2RJG	91.4%	Salmonella enterica	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00478 (show subtarget assignments)	1	soluble	YPO0469	16120798	dnaJ	chaperone protein DnaJ	379	Conserved Gene / Pathway	Phase 2: March 2008	3LZ8	32.7%	Yersinia pestis	Protein fate	Protein folding and stabilization

IDP00477 (show subtarget assignments)	1	purified	YPO3845	16123980	dapF	diaminopimelate epimerase	274	Conserved Gene / Pathway	Phase 2: March 2008	1GQZ	75.9%	Yersinia pestis	Amino acid biosynthesis	Aspartate family

IDP00897 (show subtarget assignments)	1	expressed	STM0771	16764135		putative ABC-type cobalamin/Fe3+-siderop...	258	Conserved Gene / Pathway	Phase 2: March 2008	2ONK	32.2%	Salmonella enterica	Transport and binding proteins	Cations and iron carrying compounds

IDP00896 (show subtarget assignments)	1	in_pdb 3GA7	STM0490	16763870	aes	acetyl esterase	323	Conserved Gene / Pathway	Phase 2: March 2008	3GA7	100%	Salmonella enterica	Fatty acid and phospholipid metabolism	Degradation

IDP00895 (show subtarget assignments)	1	in_pdb 3IR4	STM1165	16764521	grxB	glutaredoxin 2	215	Conserved Gene / Pathway	Phase 2: March 2008	3IR4	100%	Salmonella enterica	Biosynthesis of cofactors, prosthetic groups, and carriers	Glutathione and analogs

IDP00894 (show subtarget assignments)	1	expressed	STM4390	16767636		putative cytoplasmic protein	68	Conserved Gene / Pathway	Phase 2: March 2008			Salmonella enterica	Protein synthesis	tRNA aminoacylation

IDP00893 (show subtarget assignments)	1	soluble	STM4002	16767267		putative cytoplasmic protein	74	Conserved Gene / Pathway	Phase 2: March 2008			Salmonella enterica	Protein synthesis	tRNA aminoacylation

IDP00474 (show subtarget assignments)	1	purified	YPO2512	16122733	glnH	glutamine ABC transporter periplasmic pr...	247	Conserved Gene / Pathway	Phase 2: March 2008	1GGG	78.1%	Yersinia pestis	Transport and binding proteins	Amino acids, peptides and amines

IDP00892 (show subtarget assignments)	0	work_stopped	STM3881	16767165	rbsD	high-affinity D-ribose transport protein...	139	Conserved Gene / Pathway	Phase 2: March 2008	3DSA	100%	Salmonella enterica	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP00891 (show subtarget assignments)	0	work_stopped	STM3816	16767101	ccmD	heme exporter protein C	70	Conserved Gene / Pathway	Phase 2: March 2008			Salmonella enterica	Energy metabolism	Electron transport

IDP00520
(show subtarget assignments)

1

in_pdb
3F6M
3FPI

YPO3360

16123510

ispF

2-C-methyl-D-erythritol 2,4-cyclodiphosp...

162

Conserved Gene / Pathway

Phase 2: March 2008

3F6M

100%

Yersinia pestis

Biosynthesis of cofactors, prosthetic groups, and carriers

Other

IDP00519
(show subtarget assignments)

1

cloned

YPO3446

16123594

argI

ornithine carbamoyltransferase subunit I...

335

Conserved Gene / Pathway

Phase 2: March 2008

1AKM

79.1%

Yersinia pestis

Amino acid biosynthesis

Glutamate family

IDP00981
(show subtarget assignments)

1

purified

STM2052

16765382

pduQ

propanol dehydrogenase

370

Conserved Gene / Pathway

Phase 2: March 2008

3OWO

35.3%

Salmonella enterica

Energy metabolism

Fermentation

IDP00980
(show subtarget assignments)

1

purified

STM1970

16765308

fliG

flagellar motor switch protein G

331

Conserved Gene / Pathway

Phase 2: March 2008

3HJL

28.7%

Salmonella enterica

Cellular processes

Chemotaxis and motility

IDP00979
(show subtarget assignments)

1

purified

STM1953

16765291

yedO

D-cysteine desulfhydrase

328

Conserved Gene / Pathway

Phase 2: March 2008

1J0A

38.7%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Pyridoxine

IDP00978
(show subtarget assignments)

1

purified

STM1951

16765289

yecC

putative amino-acid ABC transporter ATP-...

250

Conserved Gene / Pathway

Phase 2: March 2008

2OLJ

54.8%

Salmonella enterica

Transport and binding proteins

Amino acids, peptides and amines

IDP00977
(show subtarget assignments)

1

expressed

STM1932

16765273

ftnB

ferritin-like protein

167

Conserved Gene / Pathway

Phase 2: March 2008

1EUM

33.5%

Salmonella enterica

Transport and binding proteins

Cations and iron carrying compounds

IDP00517
(show subtarget assignments)

1

soluble

YPMT1.71

16082863

hypothetical protein YPMT1.71

328

Conserved Gene / Pathway

Phase 2: March 2008

Yersinia pestis

Cellular processes

Cell division

IDP00516
(show subtarget assignments)

1

soluble

YPO4022

16124145

putative iron transport protein

317

Conserved Gene / Pathway

Phase 2: March 2008

3GFV

34.4%

Yersinia pestis

Transport and binding proteins

Unknown substrate

IDP00975
(show subtarget assignments)

1

cloned

STM1815

16765156

minD

cell division inhibitor MinD

270

Conserved Gene / Pathway

Phase 2: March 2008

3Q9L

93.3%

Salmonella enterica

Cellular processes

Cell division

IDP00973
(show subtarget assignments)

1

purified

STM1756

16765100

purU

formyltetrahydrofolate deformylase

280

Conserved Gene / Pathway

Phase 2: March 2008

3O1L

42.7%

Salmonella enterica

Purines, pyrimidines, nucleosides, and nucleotides

Purine ribonucleotide biosynthesis

IDP00972
(show subtarget assignments)

1

expressed

STM1743

16765087

oppD

oligopeptide transporter ATP-binding com...

335

Conserved Gene / Pathway

Phase 2: March 2008

1Z47

25.7%

Salmonella enterica

Transport and binding proteins

Amino acids, peptides and amines

IDP00971
(show subtarget assignments)

1

in_pdb
3IAH

STM1717

16765061

yciK

short chain dehydrogenase

253

Conserved Gene / Pathway

Phase 2: March 2008

3IAH

100%

Salmonella enterica

Central intermediary metabolism

Other

IDP00514
(show subtarget assignments)

1

selected

YPO3721

16123859

hemolysin

1635

Conserved Gene / Pathway

Phase 2: March 2008

3FY3

9%

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00970
(show subtarget assignments)

1

soluble

STM1682

16765025

tpx

thiol peroxidase

168

Conserved Gene / Pathway

Phase 2: March 2008

1QXH

87.5%

Salmonella enterica

Cellular processes

Detoxification

IDP00969
(show subtarget assignments)

1

purified

STM1597

161353598

ydcW

putative aldehyde dehydrogenase

474

Conserved Gene / Pathway

Phase 2: March 2008

1WNB

83.5%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Other

IDP00513
(show subtarget assignments)

1

cloned

YPO3674

16123817

putative insecticidal toxin

1011

Conserved Gene / Pathway

Phase 2: March 2008

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00512
(show subtarget assignments)

1

cloned

YPO2244

16122472

electron transport complex protein RnfC ...

620

Conserved Gene / Pathway

Phase 2: March 2008

Yersinia pestis

Unclassified

Role category not yet assigned

IDP00511
(show subtarget assignments)

1

in_pdb
3RPE

YPO0670

16120995

mdaB

putative modulator of drug activity

194

Conserved Gene / Pathway

Phase 2: March 2008

3RPE

100%

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00965
(show subtarget assignments)

1

purified

STM1463

16764811

add

adenosine deaminase

333

Conserved Gene / Pathway

Phase 2: March 2008

1NDV

33.8%

Salmonella enterica

Purines, pyrimidines, nucleosides, and nucleotides

Salvage of nucleosides and nucleotides

IDP00964
(show subtarget assignments)

0

work_stopped

STM1439

16764787

ydhF

putative aldo/keto reductase

298

Conserved Gene / Pathway

Phase 2: March 2008

1OG6

88.9%

Salmonella enterica

Unknown function

General

IDP00963
(show subtarget assignments)

1

purified

STM1436

16764784

nemA

N-ethylmaleimide reductase, FMN-linked

365

Conserved Gene / Pathway

Phase 2: March 2008

3P62

87.4%

Salmonella enterica

Central intermediary metabolism

Other

IDP00509
(show subtarget assignments)

1

in_pdb
3RY3

YPO2660

16122866

putative solute-binding protein

525

Conserved Gene / Pathway

Phase 2: March 2008

3RY3

100%

Yersinia pestis

Transport and binding proteins

Unknown substrate

IDP00961
(show subtarget assignments)

1

expressed

STM1385

16764735

ttrB

tetrathionate reductase complex subunit ...

250

Conserved Gene / Pathway

Phase 2: March 2008

2VPW

34.4%

Salmonella enterica

Energy metabolism

Electron transport

IDP00508
(show subtarget assignments)

1

expressed

YPO1315

16121597

putative hydrolase

216

Conserved Gene / Pathway

Phase 2: March 2008

3FVV

35.2%

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00959
(show subtarget assignments)

1

soluble

STM1303

16764654

argD

bifunctional succinylornithine transamin...

408

Conserved Gene / Pathway

Phase 2: March 2008

2PB0

60.8%

Salmonella enterica

Amino acid biosynthesis

Glutamate family

IDP00958
(show subtarget assignments)

1

soluble

STM1218

16764573

lolD

lipoprotein transporter ATP-binding subu...

233

Conserved Gene / Pathway

Phase 2: March 2008

2PCJ

43.3%

Salmonella enterica

Transport and binding proteins

Unknown substrate

IDP00957
(show subtarget assignments)

0

work_stopped

STM1202

16764557

ycfH

predicted metallodependent hydrolase

265

Conserved Gene / Pathway

Phase 2: March 2008

1YIX

92.8%

Salmonella enterica

Unknown function

Enzymes of unknown specificity

IDP00506
(show subtarget assignments)

1

expressed

YPO2491

16122712

putative hemolysin activator protein

562

Conserved Gene / Pathway

Phase 2: March 2008

2QDZ

21.9%

Yersinia pestis

Protein fate

Protein and peptide secretion and trafficking

IDP00955
(show subtarget assignments)

1

cloned

STM1192

16764547

plsX

fatty acid/phospholipid synthesis protei...

359

Conserved Gene / Pathway

Phase 2: March 2008

1U7N

36.5%

Salmonella enterica

Fatty acid and phospholipid metabolism

Biosynthesis

IDP00505
(show subtarget assignments)

1

purified

YPO1298

16121580

fruB

fructose-specific PTS IIA/HPr components...

377

Conserved Gene / Pathway

Phase 2: March 2008

1A3A

17%

Yersinia pestis

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP00953
(show subtarget assignments)

1

purified

STM1183

16764539

flgK

flagellar hook-associated protein FlgK

553

Conserved Gene / Pathway

Phase 2: March 2008

2D4Y

83.5%

Salmonella enterica

Cellular processes

Toxin production and resistance

IDP00952
(show subtarget assignments)

1

soluble

STM1176

16764532

flgD

flagellar basal body rod modification pr...

232

Conserved Gene / Pathway

Phase 2: March 2008

3C12

19.8%

Salmonella enterica

Cell envelope

Surface structures

IDP00951
(show subtarget assignments)

1

in_pdb
3PP8
3KBO

STM1135

16764491

ycdW

putative oxidoreductase

312

Conserved Gene / Pathway

Phase 2: March 2008

3KBO

100%

Salmonella enterica

Central intermediary metabolism

Other

IDP00950
(show subtarget assignments)

1

soluble

STM1119

16764477

wraB

TrpR binding protein WrbA

198

Conserved Gene / Pathway

Phase 2: March 2008

2R96

94.4%

Salmonella enterica

Amino acid biosynthesis

Aromatic amino acid family

IDP00949
(show subtarget assignments)

1

soluble

STM1102

16764460

hpaE

4-hydroxyphenylacetate catabolism

488

Conserved Gene / Pathway

Phase 2: March 2008

2D4E

47.7%

Salmonella enterica

Central intermediary metabolism

Other

IDP00948
(show subtarget assignments)

1

expressed

STM1060

16764419

putative iron-sulfur protein

369

Conserved Gene / Pathway

Phase 2: March 2008

1ROE

8.4%

Salmonella enterica

Energy metabolism

Electron transport

IDP00502
(show subtarget assignments)

1

selected

YPO2045

16122284

putative hemolysin

1576

Conserved Gene / Pathway

Phase 2: March 2008

3FY3

5.6%

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00946
(show subtarget assignments)

1

expressed

STM0978

16764338

aroA

3-phosphoshikimate 1-carboxyvinyltransfe...

427

Conserved Gene / Pathway

Phase 2: March 2008

1G6S

89.5%

Salmonella enterica

Amino acid biosynthesis

Aromatic amino acid family

IDP00945
(show subtarget assignments)

0

work_stopped

STM0977

16764337

serC

phosphoserine aminotransferase

362

Conserved Gene / Pathway

Phase 2: March 2008

3QM2

100%

Salmonella enterica

Amino acid biosynthesis

Serine family

IDP00501
(show subtarget assignments)

1

purified

YPO0922

16121227

epd

D-erythrose 4-phosphate dehydrogenase

338

Conserved Gene / Pathway

Phase 2: March 2008

2X5J

82.5%

Yersinia pestis

Biosynthesis of cofactors, prosthetic groups, and carriers

Pyridoxine

IDP00944
(show subtarget assignments)

1

crystallized

STM0891

16764252

artP

arginine transporter ATP-binding subunit...

242

Conserved Gene / Pathway

Phase 2: March 2008

1B0U

43.8%

Salmonella enterica

Transport and binding proteins

Amino acids, peptides and amines

IDP00943
(show subtarget assignments)

1

crystallized

STM0862

16764224

yliJ

putative glutathione S-transferase

208

Conserved Gene / Pathway

Phase 2: March 2008

1AW9

28.8%

Salmonella enterica

Cellular processes

Detoxification

IDP00500
(show subtarget assignments)

1

purified

YPO1784

16122038

putative copper resistance protein

128

Conserved Gene / Pathway

Phase 2: March 2008

1IX2

31.2%

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00499
(show subtarget assignments)

1

in_pdb
3IIE

YPO1048

16121348

dxr

1-deoxy-D-xylulose 5-phosphate reductois...

398

Conserved Gene / Pathway

Phase 2: March 2008

3IIE

100%

Yersinia pestis

Biosynthesis of cofactors, prosthetic groups, and carriers

Other

IDP00941
(show subtarget assignments)

1

purified

STM0846

16764208

moeA

molybdopterin biosynthesis protein MoeA ...

413

Conserved Gene / Pathway

Phase 2: March 2008

1FC5

87.2%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Molybdopterin

IDP00940
(show subtarget assignments)

1

soluble

STM0845

16764207

moeB

molybdopterin biosynthesis protein MoeB ...

249

Conserved Gene / Pathway

Phase 2: March 2008

1JW9

88.8%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Molybdopterin

IDP00939
(show subtarget assignments)

1

expressed

STM0828

16764190

glnQ

glutamine ABC transporter ATP-binding pr...

240

Conserved Gene / Pathway

Phase 2: March 2008

2OLJ

55%

Salmonella enterica

Transport and binding proteins

Amino acids, peptides and amines

IDP00937
(show subtarget assignments)

1

cloned

STM0795

16764158

bioF

8-amino-7-oxononanoate synthase

385

Conserved Gene / Pathway

Phase 2: March 2008

1BS0

80%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Biotin

IDP00936
(show subtarget assignments)

1

soluble

STM0793

16764156

bioA

adenosylmethionine--8-amino-7-oxononanoa...

429

Conserved Gene / Pathway

Phase 2: March 2008

1MLY

86.2%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Biotin

IDP00935
(show subtarget assignments)

1

soluble

STM0783

16764147

modC

molybdate transporter ATP-binding protei...

352

Conserved Gene / Pathway

Phase 2: March 2008

3D31

29.5%

Salmonella enterica

Transport and binding proteins

Anions

IDP00934
(show subtarget assignments)

0

work_stopped

STM0779

16764143

modE

DNA-binding transcriptional dual regulat...

262

Conserved Gene / Pathway

Phase 2: March 2008

1B9M

89.3%

Salmonella enterica

Transport and binding proteins

Anions

IDP00933
(show subtarget assignments)

1

soluble

STM0662

16764039

gltL

glutamate/aspartate transporter

241

Conserved Gene / Pathway

Phase 2: March 2008

2OLJ

54.4%

Salmonella enterica

Transport and binding proteins

Amino acids, peptides and amines

IDP00932
(show subtarget assignments)

1

purified

STM0645

16764022

nadD

nicotinic acid mononucleotide adenyltran...

213

Conserved Gene / Pathway

Phase 2: March 2008

1K4K

85.4%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Pyridine nucleotides

IDP00930
(show subtarget assignments)

1

expressed

STM0612

16763989

putative hydrogenase protein

185

Conserved Gene / Pathway

Phase 2: March 2008

2VPW

30.3%

Salmonella enterica

Energy metabolism

Anaerobic

IDP00929
(show subtarget assignments)

1

soluble

STM0603

16763980

ybdL

putative aminotransferase

386

Conserved Gene / Pathway

Phase 2: March 2008

1U08

85.5%

Salmonella enterica

Central intermediary metabolism

Other

IDP00493
(show subtarget assignments)

1

expressed

YPO1124

16121424

tolB

translocation protein TolB

430

Conserved Gene / Pathway

Phase 2: March 2008

1C5K

84.9%

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00928
(show subtarget assignments)

1

purified

STM0602

16763979

ybdH

putative glycerol dehydrogenase

362

Conserved Gene / Pathway

Phase 2: March 2008

1KQ3

31.1%

Salmonella enterica

Central intermediary metabolism

Other

IDP00927
(show subtarget assignments)

1

soluble

STM0598

16763975

entA

2,3-dihydroxybenzoate-2,3-dehydrogenase ...

251

Conserved Gene / Pathway

Phase 2: March 2008

2FWM

89.2%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Other

IDP00492
(show subtarget assignments)

1

selected

YPO1559

16121830

hypothetical protein YPO1559

379

Conserved Gene / Pathway

Phase 2: March 2008

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP00926
(show subtarget assignments)

1

soluble

STM0597

16763974

entB

2,3-dihydro-2,3-dihydroxybenzoate synthe...

285

Conserved Gene / Pathway

Phase 2: March 2008

2FQ1

88.4%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Other

IDP00491
(show subtarget assignments)

1

purified

YPO1107

16121407

heat shock protein GrpE

192

Conserved Gene / Pathway

Phase 2: March 2008

1DKG

59.4%

Yersinia pestis

Protein fate

Protein folding and stabilization

IDP00924
(show subtarget assignments)

1

purified

STM0590

16763967

fepC

iron-enterobactin transporter ATP-bindin...

264

Conserved Gene / Pathway

Phase 2: March 2008

3GFO

28.4%

Salmonella enterica

Transport and binding proteins

Cations and iron carrying compounds

IDP00923
(show subtarget assignments)

1

in_pdb
3HZN

STM0578

16763955

nfnB

dihydropteridine reductase

217

Conserved Gene / Pathway

Phase 2: March 2008

3HZN

100%

Salmonella enterica

Central intermediary metabolism

Other

IDP00490
(show subtarget assignments)

1

cloned

YPO1537

16121810

putative iron-siderophore receptor

753

Conserved Gene / Pathway

Phase 2: March 2008

3EFM

36%

Yersinia pestis

Transport and binding proteins

Cations and iron carrying compounds

IDP00922
(show subtarget assignments)

1

soluble

STM0533

16763913

purK

phosphoribosylaminoimidazole carboxylase...

355

Conserved Gene / Pathway

Phase 2: March 2008

1B6S

88.2%

Salmonella enterica

Purines, pyrimidines, nucleosides, and nucleotides

Purine ribonucleotide biosynthesis

IDP00921
(show subtarget assignments)

1

purified

STM0507

16763887

ybbA

putative ABC transporter ATP-binding pro...

228

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

42.5%

Salmonella enterica

Transport and binding proteins

Unknown substrate

IDP00489
(show subtarget assignments)

1

soluble

YPO1533

16121806

putative iron-siderophore transport syst...

282

Conserved Gene / Pathway

Phase 2: March 2008

3FVQ

28.4%

Yersinia pestis

Transport and binding proteins

Cations and iron carrying compounds

IDP00920
(show subtarget assignments)

1

purified

STM0417

16763797

ribH

riboflavin synthase subunit beta

156

Conserved Gene / Pathway

Phase 2: March 2008

3MK3

100%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Riboflavin, FMN, and FAD

IDP00919
(show subtarget assignments)

1

in_pdb
3Q1K
3I12

STM0380

16763760

ddl

D-alanyl-alanine synthetase A

364

Conserved Gene / Pathway

Phase 2: March 2008

3I12

100%

Salmonella enterica

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00918
(show subtarget assignments)

1

soluble

STM0372

16763752

hemB

delta-aminolevulinic acid dehydratase

324

Conserved Gene / Pathway

Phase 2: March 2008

1I8J

93.5%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Heme, porphyrin, and cobalamin

IDP00917
(show subtarget assignments)

1

cloned

STM0355

16763735

putative copper chaperone

64

Conserved Gene / Pathway

Phase 2: March 2008

2K2P

39.1%

Salmonella enterica

Transport and binding proteins

Cations and iron carrying compounds

IDP00487
(show subtarget assignments)

1

soluble

YPO1491

16121764

ABC transporter ATP-binding protein

531

Conserved Gene / Pathway

Phase 2: March 2008

3BK7

24.7%

Yersinia pestis

Transport and binding proteins

Unknown substrate

IDP00916
(show subtarget assignments)

0

work_stopped

STM0247

16763636

metN

DL-methionine transporter ATP-binding su...

343

Conserved Gene / Pathway

Phase 2: March 2008

3DHW

95.3%

Salmonella enterica

Transport and binding proteins

Unknown substrate

IDP00486
(show subtarget assignments)

1

expressed

YPO1463

16121738

putative acyl transferase

282

Conserved Gene / Pathway

Phase 2: March 2008

3RGI

47.2%

Yersinia pestis

Fatty acid and phospholipid metabolism

Biosynthesis

IDP00850
(show subtarget assignments)

1

soluble

SACOL2389

57285120

transcriptional regulatory protein DegU,...

217

Conserved Gene / Pathway

Phase 2: March 2008

1A04

31.3%

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00914
(show subtarget assignments)

1

soluble

STM0220

16763610

dxr

1-deoxy-D-xylulose 5-phosphate reductois...

398

Conserved Gene / Pathway

Phase 2: March 2008

1K5H

88.7%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Other

IDP00913
(show subtarget assignments)

0

work_stopped

STM0219

16763609

frr

ribosome recycling factor

185

Conserved Gene / Pathway

Phase 2: March 2008

1EK8

94.1%

Salmonella enterica

Protein synthesis

Translation factors

IDP00912
(show subtarget assignments)

1

soluble

STM0193

16763583

fhuD

iron-hydroxamate transporter substrate-b...

296

Conserved Gene / Pathway

Phase 2: March 2008

1ESZ

75%

Salmonella enterica

Transport and binding proteins

Cations and iron carrying compounds

IDP00911
(show subtarget assignments)

1

expressed

STM0191

16763581

fhuA

ferrichrome outer membrane transporter

729

Conserved Gene / Pathway

Phase 2: March 2008

2FCP

72.3%

Salmonella enterica

Cell envelope

Other

IDP00484
(show subtarget assignments)

1

cloned

YPO1417

16121697

putative iron-sulfur binding protein

370

Conserved Gene / Pathway

Phase 2: March 2008

2PIA

7%

Yersinia pestis

Energy metabolism

Electron transport

IDP00909
(show subtarget assignments)

0

work_stopped

STM0171

16763561

yadF

carbonic anhydrase

220

Conserved Gene / Pathway

Phase 2: March 2008

3QY1

100%

Salmonella enterica

Central intermediary metabolism

Other

IDP00908
(show subtarget assignments)

1

expressed

STM0143

16763533

hofB

hypothetical protein STM0143

461

Conserved Gene / Pathway

Phase 2: March 2008

1P9R

37.3%

Salmonella enterica

Cell envelope

Surface structures

IDP00907
(show subtarget assignments)

1

purified

STM0140

16763530

coaE

dephospho-CoA kinase

206

Conserved Gene / Pathway

Phase 2: March 2008

1N3B

88.8%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Other

IDP00904
(show subtarget assignments)

0

work_stopped

STM0124

16763514

murF

UDP-N-acetylmuramoyl-tripeptide--D-alany...

452

Conserved Gene / Pathway

Phase 2: March 2008

1GG4

87.6%

Salmonella enterica

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00480
(show subtarget assignments)

1

soluble

YPO3118

16123283

adk

adenylate kinase

214

Conserved Gene / Pathway

Phase 2: March 2008

1AKE

87.4%

Yersinia pestis

Purines, pyrimidines, nucleosides, and nucleotides

Nucleotide and nucleoside interconversions

IDP00902
(show subtarget assignments)

1

expressed

STM0045

16763435

ribF

bifunctional riboflavin kinase/FMN adeny...

312

Conserved Gene / Pathway

Phase 2: March 2008

1MRZ

33%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Riboflavin, FMN, and FAD

IDP00901
(show subtarget assignments)

1

purified

STM0004

16763394

thrC

threonine synthase

428

Conserved Gene / Pathway

Phase 2: March 2008

1VB3

93.5%

Salmonella enterica

Amino acid biosynthesis

Aspartate family

IDP00479
(show subtarget assignments)

1

in_pdb
3H07

YPO0658

16120983

ribB

3,4-dihydroxy-2-butanone 4-phosphate syn...

217

Conserved Gene / Pathway

Phase 2: March 2008

3H07

100%

Yersinia pestis

Biosynthesis of cofactors, prosthetic groups, and carriers

Riboflavin, FMN, and FAD

IDP00900
(show subtarget assignments)

0

work_stopped

STM4247

16767497

alr

alanine racemase

359

Conserved Gene / Pathway

Phase 2: March 2008

2RJG

91.4%

Salmonella enterica

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00478
(show subtarget assignments)

1

soluble

YPO0469

16120798

dnaJ

chaperone protein DnaJ

379

Conserved Gene / Pathway

Phase 2: March 2008

3LZ8

32.7%

Yersinia pestis

Protein fate

Protein folding and stabilization

IDP00477
(show subtarget assignments)

1

purified

YPO3845

16123980

dapF

diaminopimelate epimerase

274

Conserved Gene / Pathway

Phase 2: March 2008

1GQZ

75.9%

Yersinia pestis

Amino acid biosynthesis

Aspartate family

IDP00897
(show subtarget assignments)

1

expressed

STM0771

16764135

putative ABC-type cobalamin/Fe3+-siderop...

258

Conserved Gene / Pathway

Phase 2: March 2008

2ONK

32.2%

Salmonella enterica

Transport and binding proteins

Cations and iron carrying compounds

IDP00896
(show subtarget assignments)

1

in_pdb
3GA7

STM0490

16763870

aes

acetyl esterase

323

Conserved Gene / Pathway

Phase 2: March 2008

3GA7

100%

Salmonella enterica

Fatty acid and phospholipid metabolism

Degradation

IDP00895
(show subtarget assignments)

1

in_pdb
3IR4

STM1165

16764521

grxB

glutaredoxin 2

215

Conserved Gene / Pathway

Phase 2: March 2008

3IR4

100%

Salmonella enterica

Biosynthesis of cofactors, prosthetic groups, and carriers

Glutathione and analogs

IDP00894
(show subtarget assignments)

1

expressed

STM4390

16767636

putative cytoplasmic protein

68

Conserved Gene / Pathway

Phase 2: March 2008

Salmonella enterica

Protein synthesis

tRNA aminoacylation

IDP00893
(show subtarget assignments)

1

soluble

STM4002

16767267

putative cytoplasmic protein

74

Conserved Gene / Pathway

Phase 2: March 2008

Salmonella enterica

Protein synthesis

tRNA aminoacylation

IDP00474
(show subtarget assignments)

1

purified

YPO2512

16122733

glnH

glutamine ABC transporter periplasmic pr...

247

Conserved Gene / Pathway

Phase 2: March 2008

1GGG

78.1%

Yersinia pestis

Transport and binding proteins

Amino acids, peptides and amines

IDP00892
(show subtarget assignments)

0

work_stopped

STM3881

16767165

rbsD

high-affinity D-ribose transport protein...

139

Conserved Gene / Pathway

Phase 2: March 2008

3DSA

100%

Salmonella enterica

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP00891
(show subtarget assignments)

0

work_stopped

STM3816

16767101

ccmD

heme exporter protein C

70

Conserved Gene / Pathway

Phase 2: March 2008

Salmonella enterica

Energy metabolism

Electron transport

Targets