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Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
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Keyword:
Type Keyword
Stage:
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cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
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CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP02359
(
show subtarget assignments
)
1
purified
Cj0319
15791687
fliG
flagellar motor switch protein G [Campyl...
342
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
3PKR
49.1%
Campylobacter jejuni
Cell envelope
Surface structures
IDP02242
(
show subtarget assignments
)
1
cloned
Cj0320
15791688
fliH
flagellar assembly protein H [Campylobac...
276
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Biosynthesis of cofactors, prosthetic groups, and carriers
Other
IDP02786
(
show subtarget assignments
)
1
purified
Cj0322
15791690
perR
FUR family transcriptional regulator [Ca...
136
Predicted virulence-Iron Scavenging Mechanisms
Phase 3: June 2008
2FE3
32.4%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP90849
(
show subtarget assignments
)
8
in_pdb
3M5U
Cj0326
15791694
serC
phosphoserine aminotransferase [Campylob...
358
Predicted Essential
Community Requests
3M5U
100%
Campylobacter jejuni
IDP90814
(
show subtarget assignments
)
8
soluble
Cj0329c
15791697
plsX
putative glycerol-3-phosphate acyltransf...
328
Predicted Essential
Community Requests
1VI1
38.4%
Campylobacter jejuni
IDP90542
(
show subtarget assignments
)
8
in_pdb
3PJ9
Cj0332c
15791700
ndk
nucleoside diphosphate kinase [Campyloba...
137
Predicted Essential
Community Requests
3PJ9
100%
Campylobacter jejuni
IDP00330
(
show subtarget assignments
)
1
soluble
Cj0345
15791713
trpE
putative anthranilate synthase component...
416
Drug Target Function
Phase 2: March 2008
1QDL
32%
Campylobacter jejuni
Amino acid biosynthesis
Aromatic amino acid family
IDP00322
(
show subtarget assignments
)
1
expressed
Cj0346
15791714
trpD
anthranilate synthase component II
533
Drug Target Function
Phase 2: March 2008
1VQU
20.6%
Campylobacter jejuni
Amino acid biosynthesis
Aromatic amino acid family
IDP90509
(
show subtarget assignments
)
8
purified
Cj0347
15791715
trpF
N-(5'phosphoribosyl)anthranilate isomera...
199
Predicted Essential
Community Requests
1DL3
31.4%
Campylobacter jejuni
IDP90720
(
show subtarget assignments
)
8
purified
Cj0348
15791716
trpB
tryptophan synthase subunit beta [Campyl...
392
Predicted Essential
Community Requests
1V8Z
51.5%
Campylobacter jejuni
IDP90540
(
show subtarget assignments
)
8
in_pdb
3THA
Cj0349
15791717
trpA
tryptophan synthase subunit alpha [Campy...
249
Predicted Essential
Community Requests
3THA
100%
Campylobacter jejuni
IDP01715
(
show subtarget assignments
)
1
expressed
Cj0351
15791719
fliN
flagellar motor switch protein [Campylob...
102
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
1O6A
29.4%
Campylobacter jejuni
Cell envelope
Other
IDP02364
(
show subtarget assignments
)
1
cloned
Cj0365c
15791732
putative outer membrane channel protein ...
492
Predicted virulence-Resistance to antibiotics and toxic compounds; Possible Vacc...
Phase 3: June 2008
3PIK
24.8%
Campylobacter jejuni
Cellular processes
Toxin production and resistance
IDP02813
(
show subtarget assignments
)
1
cloned
Cj0367c
15791734
RND efflux system, membrane fusion prote...
367
Predicted virulence-Resistance to antibiotics and toxic compounds
Phase 3: June 2008
1T5E
29.2%
Campylobacter jejuni
Regulatory functions
Other
IDP90546
(
show subtarget assignments
)
8
in_pdb
3RU6
Cj0381c
15791748
pyrF
orotidine 5'-phosphate decarboxylase [Ca...
279
Predicted Essential
Community Requests
3RU6
100%
Campylobacter jejuni
IDP90519
(
show subtarget assignments
)
8
purified
Cj0383c
15791750
ribH
riboflavin synthase subunit beta [Campyl...
154
Predicted Essential
Community Requests
1HQK
51.9%
Campylobacter jejuni
IDP90656
(
show subtarget assignments
)
8
purified
Cj0384c
15791751
kdsA
2-dehydro-3-deoxyphosphooctonate aldolas...
271
Predicted Essential
Community Requests
1FWN
55.7%
Campylobacter jejuni
IDP90555
(
show subtarget assignments
)
8
in_pdb
3M5W
3TZL
Cj0388
15791755
trpS
tryptophanyl-tRNA synthetase [Campylobac...
319
Predicted Essential
Community Requests
3M5W
100%
Campylobacter jejuni
IDP90689
(
show subtarget assignments
)
8
soluble
Cj0389
15791756
serS
seryl-tRNA synthetase [Campylobacter jej...
411
Predicted Essential
Community Requests
2DQ3
48.4%
Campylobacter jejuni
IDP90685
(
show subtarget assignments
)
8
purified
Cj0401
15791768
lysS
lysyl-tRNA synthetase [Campylobacter jej...
501
Predicted Essential
Community Requests
1BBU
48.1%
Campylobacter jejuni
IDP90682
(
show subtarget assignments
)
8
in_pdb
3N0L
Cj0402
15791769
glyA
serine hydroxymethyltransferase [Campylo...
414
Predicted Essential
Community Requests
3N0L
100%
Campylobacter jejuni
IDP90864
(
show subtarget assignments
)
8
expressed
Cj0405
15791772
aroE
shikimate 5-dehydrogenase [Campylobacter...
262
Predicted Essential
Community Requests
3PHG
38.5%
Campylobacter jejuni
IDP90636
(
show subtarget assignments
)
8
purified
Cj0432c
15791799
murD
UDP-N-acetylmuramoyl-L-alanyl-D-glutamat...
402
Predicted Essential
Community Requests
1E0D
27.6%
Campylobacter jejuni
IDP90562
(
show subtarget assignments
)
8
purified
Cj0434
15791801
pgm
phosphoglyceromutase [Campylobacter jeju...
492
Predicted Essential
Community Requests
1EJJ
44%
Campylobacter jejuni
IDP05748
(
show subtarget assignments
)
1
cloned
Cj0435
6967908
fabG
phosphoglycerate mutase [Campylobacter j...
247
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2P68
48.8%
Campylobacter jejuni
Fatty acid and phospholipid metabolism: Biosynthesis
IDP90856
(
show subtarget assignments
)
8
crystallized
Cj0442
15791809
fabF
3-oxoacyl-(acyl carrier protein) synthas...
404
Predicted Essential
Community Requests
1J3N
52.7%
Campylobacter jejuni
IDP90710
(
show subtarget assignments
)
8
purified
Cj0451
15791815
rep
ribulose-phosphate 3-epimerase [Campylob...
215
Predicted Essential
Community Requests
1RPX
48.4%
Campylobacter jejuni
IDP90599
(
show subtarget assignments
)
8
purified
Cj0460
15791824
nusA
transcription elongation factor NusA [Ca...
362
Predicted Essential
Community Requests
1HH2
33.4%
Campylobacter jejuni
IDP05649
(
show subtarget assignments
)
1
expressed
Cj0464
6967934
recG
zinc protease-like protein [Campylobacte...
607
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1GM5
28.8%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP90699
(
show subtarget assignments
)
8
cloned
Cj0478
15791842
rpoB
DNA-directed RNA polymerase subunit beta...
1378
Predicted Essential
Community Requests
3IYD
47.9%
Campylobacter jejuni
IDP90573
(
show subtarget assignments
)
8
cloned
Cj0479
15791843
rpoC
DNA-directed RNA polymerase beta' chain ...
1517
Predicted Essential
Community Requests
3IYD
46.1%
Campylobacter jejuni
IDP90754
(
show subtarget assignments
)
8
purified
Cj0498
15791862
trpC
indole-3-glycerol phosphate synthase [Ca...
258
Predicted Essential
Community Requests
3TSM
39%
Campylobacter jejuni
IDP90719
(
show subtarget assignments
)
8
soluble
Cj0503c
15791865
hemH
ferrochelatase [Campylobacter jejuni sub...
303
Predicted Essential
Community Requests
2PO7
31%
Campylobacter jejuni
IDP90679
(
show subtarget assignments
)
8
cloned
Cj0506
15791868
alaS
alanyl-tRNA synthetase [Campylobacter je...
842
Predicted Essential
Community Requests
3HXU
28.5%
Campylobacter jejuni
IDP05542
(
show subtarget assignments
)
1
cloned
Cj0508
6967973
pbpA
hypothetical protein Cj0504c [Campylobac...
643
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
3FWL
31.1%
Campylobacter jejuni
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP90788
(
show subtarget assignments
)
8
purified
Cj0512
15791874
purC
phosphoribosylaminoimidazole-succinocarb...
236
Predicted Essential
Community Requests
3NUA
50.8%
Campylobacter jejuni
IDP90514
(
show subtarget assignments
)
8
crystallized
Cj0513
15791875
phosphoribosylformylglycinamidine syntha...
81
Predicted Essential
Community Requests
1T4A
46.9%
Campylobacter jejuni
IDP90827
(
show subtarget assignments
)
8
expressed
Cj0514
15791876
purQ
phosphoribosylformylglycinamidine syntha...
223
Predicted Essential
Community Requests
3D54
40.4%
Campylobacter jejuni
IDP01827
(
show subtarget assignments
)
1
expressed
Cj0526c
15791887
fliE
flagellar hook-basal body protein FliE [...
98
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP02754
(
show subtarget assignments
)
1
expressed
Cj0527c
15791888
flgC
flagellar basal body rod protein FlgC [C...
164
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP01714
(
show subtarget assignments
)
1
cloned
Cj0528c
15791889
flgB
flagellar basal body rod protein FlgB [C...
143
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP90676
(
show subtarget assignments
)
8
expressed
Cj0533
15791894
sucC
succinyl-CoA synthase, beta subunit [Cam...
387
Predicted Essential
Community Requests
1CQI
45.5%
Campylobacter jejuni
IDP90715
(
show subtarget assignments
)
8
expressed
Cj0534
15791895
sucD
succinyl-CoA synthase, alpha subunit [Ca...
289
Predicted Essential
Community Requests
1JKJ
58.1%
Campylobacter jejuni
IDP90516
(
show subtarget assignments
)
8
expressed
Cj0535
15791896
oorD
2-oxoglutarate-acceptor oxidoreductase s...
103
Predicted Essential
Community Requests
1HFE
31.1%
Campylobacter jejuni
IDP90568
(
show subtarget assignments
)
8
soluble
Cj0536
15791897
oorA
2-oxoglutarate-acceptor oxidoreductase s...
374
Predicted Essential
Community Requests
1YD7
43%
Campylobacter jejuni
IDP90674
(
show subtarget assignments
)
8
cloned
Cj0542
15791903
hemA
glutamyl-tRNA reductase [Campylobacter j...
432
Predicted Essential
Community Requests
1GPJ
27.3%
Campylobacter jejuni
IDP90581
(
show subtarget assignments
)
8
soluble
Cj0543
15791904
proS
prolyl-tRNA synthetase [Campylobacter je...
569
Predicted Essential
Community Requests
2J3L
42.8%
Campylobacter jejuni
IDP05650
(
show subtarget assignments
)
1
soluble
Cj0543
6968007
proS
hypothetical protein Cj0539 [Campylobact...
569
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2J3L
42.8%
Campylobacter jejuni
Protein synthesis: tRNA aminoacylation
IDP90701
(
show subtarget assignments
)
8
soluble
Cj0545
15791906
hemC
porphobilinogen deaminase [Campylobacter...
307
Predicted Essential
Community Requests
1AH5
47.9%
Campylobacter jejuni
IDP02137
(
show subtarget assignments
)
1
soluble
Cj0547
15791908
flaG
flagellar protein FlaG [Campylobacter je...
121
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Biosynthesis of cofactors, prosthetic groups, and carriers
Heme, porphyrin, and cobalamin
IDP02248
(
show subtarget assignments
)
1
cloned
Cj0548
15791909
fliD
flagellar capping protein [Campylobacter...
642
Known Predicted virulence-flagella; Possible Vaccine Candidate; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Protein synthesis
tRNA aminoacylation
IDP02571
(
show subtarget assignments
)
1
expressed
Cj0549
15791910
fliS
flagellar protein FliS [Campylobacter je...
128
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
3IQC
58.6%
Campylobacter jejuni
Cell envelope
Other
IDP05073
(
show subtarget assignments
)
1
expressed
Cj0562
6968026
dnaB
gamma-glutamyl phosphate reductase [Camp...
439
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2VYE
37.1%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP90729
(
show subtarget assignments
)
8
crystallized
Cj0572
15791932
ribA
bifunctional 3,4-dihydroxy-2-butanone 4-...
339
Predicted Essential
Community Requests
3MGZ
29.5%
Campylobacter jejuni
IDP02401
(
show subtarget assignments
)
1
cloned
Cj0574
15791934
ilvI
acetolactate synthase 3 catalytic subuni...
566
Possible Vaccine Candidate; Predicted Essential-Modeling
Phase 3: June 2008
1JSC
40.7%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP90778
(
show subtarget assignments
)
8
soluble
Cj0575
15791935
ilvH
acetolactate synthase 3 regulatory subun...
154
Predicted Essential
Community Requests
2F1F
40.3%
Campylobacter jejuni
IDP90716
(
show subtarget assignments
)
8
soluble
Cj0576
15791936
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine...
321
Predicted Essential
Community Requests
2IU8
35.5%
Campylobacter jejuni
IDP02138
(
show subtarget assignments
)
1
expressed
Cj0580c
15791940
coproporphyrinogen III oxidase [Campylob...
355
Predicted virulence-Iron Scavenging Mechanisms
Phase 3: June 2008
1OLT
22.5%
Campylobacter jejuni
Amino acid biosynthesis
Pyruvate family
IDP90746
(
show subtarget assignments
)
8
purified
Cj0582
15791942
lysC
aspartate kinase [Campylobacter jejuni s...
400
Predicted Essential
Community Requests
3AB4
48.9%
Campylobacter jejuni
IDP90642
(
show subtarget assignments
)
8
purified
Cj0585
15791945
folP
dihydropteroate synthase [Campylobacter ...
380
Predicted Essential
Community Requests
1AJ0
25.8%
Campylobacter jejuni
IDP90753
(
show subtarget assignments
)
8
purified
Cj0586
15791946
ligA
NAD-dependent DNA ligase LigA [Campyloba...
647
Predicted Essential
Community Requests
2OWO
40.7%
Campylobacter jejuni
IDP90687
(
show subtarget assignments
)
8
in_pdb
3QM3
Cj0597
15791957
fba
fructose-bisphosphate aldolase [Campylob...
354
Predicted Essential
Community Requests
3QM3
100%
Campylobacter jejuni
IDP02421
(
show subtarget assignments
)
1
purified
Cj0606
15791966
macrolide-specific efflux protein macA [...
390
Predicted virulence-Resistance to antibiotics and toxic compounds
Phase 3: June 2008
3FPP
28.2%
Campylobacter jejuni
Transport and binding proteins
Other
IDP02269
(
show subtarget assignments
)
1
cloned
Cj0608
15791968
outer membrane efflux protein [Campyloba...
456
Predicted virulence-Resistance to antibiotics and toxic compounds
Phase 3: June 2008
3PIK
23.7%
Campylobacter jejuni
Protein fate
Protein folding and stabilization
IDP90757
(
show subtarget assignments
)
8
purified
Cj0632
15791992
ilvC
ketol-acid reductoisomerase [Campylobact...
340
Predicted Essential
Community Requests
1NP3
64.7%
Campylobacter jejuni
IDP02084
(
show subtarget assignments
)
1
purified
Cj0639c
15791999
adk
adenylate kinase [Campylobacter jejuni s...
192
Possible Vaccine Candidate; Predicted Essential-Modeling
Phase 3: June 2008
1P4S
34.9%
Campylobacter jejuni
Energy metabolism
Electron transport
IDP90630
(
show subtarget assignments
)
8
soluble
Cj0640c
15792000
aspS
aspartyl-tRNA synthetase [Campylobacter ...
583
Predicted Essential
Community Requests
1C0A
51.8%
Campylobacter jejuni
IDP90839
(
show subtarget assignments
)
8
purified
Cj0641
15792001
ATP-NAD kinase, putative [Campylobacter ...
286
Predicted Essential
Community Requests
2AN1
31.9%
Campylobacter jejuni
IDP90836
(
show subtarget assignments
)
8
purified
Cj0647
15792007
phosphatase, YrbI family [Campylobacter ...
162
Predicted Essential
Community Requests
2R8E
38.3%
Campylobacter jejuni
IDP90768
(
show subtarget assignments
)
8
purified
Cj0665c
15792020
argG
argininosuccinate synthase [Campylobacte...
406
Predicted Essential
Community Requests
1J1Z
57.9%
Campylobacter jejuni
IDP90760
(
show subtarget assignments
)
8
expressed
Cj0686
15792035
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosph...
357
Predicted Essential
Community Requests
3NOY
47.1%
Campylobacter jejuni
IDP01716
(
show subtarget assignments
)
1
cloned
Cj0687c
15792036
flgH
flagellar basal body L-ring protein [Cam...
232
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP02680
(
show subtarget assignments
)
1
soluble
Cj0697
15792046
flgG2
flagellar basal-body rod protein [Campyl...
270
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP02695
(
show subtarget assignments
)
1
soluble
Cj0698
15792047
flgG
flagellar basal body rod protein FlgG [C...
263
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
3A69
23.6%
Campylobacter jejuni
Unknown function
Enzymes of unknown specificity
IDP90677
(
show subtarget assignments
)
8
crystallized
Cj0702
15792051
purE
phosphoribosylaminoimidazole carboxylase...
164
Predicted Essential
Community Requests
3TRH
53.7%
Campylobacter jejuni
IDP90793
(
show subtarget assignments
)
8
in_pdb
3RF1
3RGL
3UFG
Cj0704
15792053
glyQ
glycyl-tRNA synthetase subunit alpha [Ca...
287
Predicted Essential
Community Requests
3RF1
100%
Campylobacter jejuni
IDP90650
(
show subtarget assignments
)
8
expressed
Cj0713
15792062
trmD
tRNA (guanine-N(1)-)-methyltransferase [...
234
Predicted Essential
Community Requests
3KY7
38%
Campylobacter jejuni
IDP90624
(
show subtarget assignments
)
8
cloned
Cj0718
15792067
dnaE
DNA polymerase III subunit alpha [Campyl...
1200
Predicted Essential
Community Requests
2HPI
37%
Campylobacter jejuni
IDP01936
(
show subtarget assignments
)
1
cloned
Cj0720c
15792069
flaC
flagellin subunit protein FlaC [Campylob...
249
Known Predicted virulence-flagella; Predicted virulence-Adhesion of Campylobacte...
Phase 3: June 2008
3K8V
21.7%
Campylobacter jejuni
Protein synthesis
Ribosomal proteins: synthesis and modification
IDP01937
(
show subtarget assignments
)
0
work_stopped
Cj0727
15792076
putative periplasmic solute-binding prot...
348
Predicted virulence-Iron Scavenging Mechanisms
Phase 3: June 2008
1Y4T
19.5%
Campylobacter jejuni
Cell envelope
Other
IDP02342
(
show subtarget assignments
)
1
expressed
Cj0737
15792086
putative periplasmic protein [Campylobac...
358
Predicted virulence-Adhesion of Campylobacter; Possible Vaccine Candidate
Phase 3: June 2008
2ODL
28.8%
Campylobacter jejuni
Transport and binding proteins
Other
IDP01945
(
show subtarget assignments
)
1
cloned
Cj0739
15792088
hypothetical protein Cj0739 [Campylobact...
57
Predicted virulence-Adhesion of Campylobacter
Phase 3: June 2008
Campylobacter jejuni
Central intermediary metabolism
Other
IDP01687
(
show subtarget assignments
)
1
cloned
Cj0740
15792089
hypothetical protein Cj0740 [Campylobact...
54
Predicted virulence-Adhesion of Campylobacter
Phase 3: June 2008
Campylobacter jejuni
Transport and binding proteins
Amino acids, peptides and amines
IDP02385
(
show subtarget assignments
)
1
cloned
Cj0755
15792094
cfrA
putative iron uptake protein [Campylobac...
696
Predicted virulence-Iron Scavenging Mechanisms; Possible Vaccine Candidate
Phase 3: June 2008
2HDF
29.8%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP90794
(
show subtarget assignments
)
8
soluble
Cj0763c
15792101
cysE
serine acetyltransferase [Campylobacter ...
212
Predicted Essential
Community Requests
3P1B
34.9%
Campylobacter jejuni
IDP90766
(
show subtarget assignments
)
8
purified
Cj0765c
15792103
hisS
histidyl-tRNA synthetase [Campylobacter ...
408
Predicted Essential
Community Requests
1HTT
37.5%
Campylobacter jejuni
IDP90678
(
show subtarget assignments
)
8
purified
Cj0766c
15792104
tdk
thymidylate kinase [Campylobacter jejuni...
192
Predicted Essential
Community Requests
3HJN
33.8%
Campylobacter jejuni
IDP90508
(
show subtarget assignments
)
8
purified
Cj0767c
15792105
coaD
phosphopantetheine adenylyltransferase [...
158
Predicted Essential
Community Requests
3NV7
53.8%
Campylobacter jejuni
IDP90590
(
show subtarget assignments
)
8
cloned
Cj0770c
15792108
lipoprotein, NLPA family [Campylobacter ...
258
Predicted Essential
Community Requests
1P99
35.7%
Campylobacter jejuni
IDP90639
(
show subtarget assignments
)
8
cloned
Cj0771c
15792109
lipoprotein, NLPA family [Campylobacter ...
256
Predicted Essential
Community Requests
3TQW
39.8%
Campylobacter jejuni
IDP90739
(
show subtarget assignments
)
8
purified
Cj0772c
15792110
lipoprotein, NLPA family [Campylobacter ...
257
Predicted Essential
Community Requests
3TQW
38.5%
Campylobacter jejuni
IDP90824
(
show subtarget assignments
)
8
soluble
Cj0774c
15792112
ABC transporter ATP-binding protein [Cam...
336
Predicted Essential
Community Requests
3DHW
38.2%
Campylobacter jejuni
IDP05749
(
show subtarget assignments
)
1
cloned
Cj0775c
6968216
valS
putative periplasmic protein [Campylobac...
870
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1GAX
38.2%
Campylobacter jejuni
Protein synthesis: tRNA aminoacylation
IDP90640
(
show subtarget assignments
)
8
cloned
Cj0798c
15792136
ddl
D-alanyl-alanine synthetase A [Campyloba...
346
Predicted Essential
Community Requests
2PVP
54%
Campylobacter jejuni
IDP05336
(
show subtarget assignments
)
1
soluble
Cj0799c
6968240
ruvA
hypothetical protein Cj0794 [Campylobact...
183
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1IXR
32.5%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP90741
(
show subtarget assignments
)
8
soluble
Cj0802
15792140
cysS
cysteinyl-tRNA synthetase [Campylobacter...
462
Predicted Essential
Community Requests
3TQO
40%
Campylobacter jejuni
IDP91080
(
show subtarget assignments
)
8
cloned
Cj0803
6968244
msbA
lipid export ABC transport protein
580
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
31.6%
Campylobacter jejuni
IDP01686
(
show subtarget assignments
)
1
cloned
Cj0804
15792142
pyrD
dihydroorotate dehydrogenase 2 [Campylob...
352
Possible Vaccine Candidate; Predicted Essential-Modeling
Phase 3: June 2008
1UUM
40.3%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP90711
(
show subtarget assignments
)
8
in_pdb
3LER
3M5V
Cj0806
15792144
dapA
dihydrodipicolinate synthase [Campylobac...
298
Predicted Essential
Community Requests
3M5V
100%
Campylobacter jejuni
IDP01951
(
show subtarget assignments
)
1
purified
Cj0809c
15792147
metallo-beta-lactamase family protein [C...
198
Predicted virulence-Resistance to antibiotics and toxic compounds
Phase 3: June 2008
2ZWR
30.8%
Campylobacter jejuni
Unknown function
General
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