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Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
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8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
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CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90082
(
show subtarget assignments
)
8
purified
P03493.2
85681917
RecName: Full=Matrix protein 2; AltName:...
109
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2KJ1
64.2%
Influenza B
IDP00341
(
show subtarget assignments
)
1
cloned
FTT1305c
56708363
murA
UDP-N-acetylglucosamine 1-carboxyvinyltr...
444
Drug Target Function
Phase 2: March 2008
3SG1
32.7%
Francisella tularensis
IDP90087
(
show subtarget assignments
)
8
cloned
ZZZ_0003
168
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90092
(
show subtarget assignments
)
8
purified
ZZZ_0008
155
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90085
(
show subtarget assignments
)
8
purified
ZZZ_0001
158
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90086
(
show subtarget assignments
)
8
expressed
ZZZ_0002
492
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90089
(
show subtarget assignments
)
8
expressed
ZZZ_0005
600
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90088
(
show subtarget assignments
)
8
soluble
ZZZ_0004
140
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90090
(
show subtarget assignments
)
8
expressed
ZZZ_0006
310
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90409
(
show subtarget assignments
)
8
purified
CT_667
3329118
hypothetical protein [Chlamydia trachoma...
149
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90094
(
show subtarget assignments
)
8
cloned
ZZZ_0010
358
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90100
(
show subtarget assignments
)
8
expressed
ZZZ_0016
849
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
1QVR
36.8%
Escherichia coli
IDP90093
(
show subtarget assignments
)
8
expressed
ZZZ_0009
99
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90414
(
show subtarget assignments
)
8
expressed
CT_429
3328859
hypothetical protein [Chlamydia trachoma...
329
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90096
(
show subtarget assignments
)
8
expressed
ZZZ_0012
476
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90095
(
show subtarget assignments
)
8
soluble
ZZZ_0011
184
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90098
(
show subtarget assignments
)
8
purified
ZZZ_0014
196
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90097
(
show subtarget assignments
)
8
cloned
ZZZ_0013
104
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90104
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_004
68449081
ankyrin-like protein [Monkeypox virus]
437
similar to CPXV-GRI-C1L, MPXV-ZAI96-D1L/N4R
Community Requests
2Y1L
9.6%
Monkeypox virus
IDP90108
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_013
68449087
bifunctional zinc finger-like protein/E3...
242
similar to VARV BEN68-zinc finger-like protein
Community Requests
2ECW
8.3%
Monkeypox virus
IDP90105
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_008
68449082
unknown [Monkeypox virus]
56
similar to part of CPXV-GRI-C3L
Community Requests
Monkeypox virus
IDP90106
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_011
68449085
secreted epidermal growth factor-like pr...
142
similar to VACV-COP-C11R, MPXV-ZAI96-D3R
Community Requests
1K36
16.2%
Monkeypox virus
IDP90109
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_014
68449088
interleukin-18-binding protein [Monkeypo...
126
similar to VACWR-C12L,VARV-BSH75_banu-D7L, MPXV-ZAI96-D6L
Community Requests
3F62
79.4%
Monkeypox virus
IDP90110
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_015
68449089
ankyrin-like protein [Monkeypox virus]
660
similar to CPXV-GRI-C9L,CPXV-BR-V024, MPXV-ZAI96-D7L
Community Requests
1N0Q
4.4%
Monkeypox virus
IDP90112
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_019
68449093
unknown [Monkeypox virus]
153
similar to VACV-COP-C6L, MPXV-ZAI96-D11L
Community Requests
Monkeypox virus
IDP90113
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_021
68449095
unknown [Monkeypox virus]
315
similar to VACV-COP-C4L, MPXV-ZAI96-D13L
Community Requests
Monkeypox virus
IDP90118
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_028
68449102
alpha-amanitin target protein [Monkeypox...
177
similar to VACV-COP-N2L, MPXV-ZAI96-P2L
Community Requests
Monkeypox virus
IDP90125
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_038
68449112
kelch-like protein [Monkeypox virus]
485
similar to VACV-COP-F3L, MPXV-ZAI96-C9L
Community Requests
1ZGK
13.6%
Monkeypox virus
IDP90117
(
show subtarget assignments
)
8
purified
MPXV_ZAI1979_005_027
68449101
virokine protein [Monkeypox virus]
117
similar to VACV-COP-N1L, MPXV-ZAI96-P1L
Community Requests
2I39
89.7%
Monkeypox virus
IDP90423
(
show subtarget assignments
)
8
cloned
CT_444
3328876
omcA
9kDa-Cysteine-Rich Lipoprotein [Chlamydi...
88
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90120
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_030
68449104
unknown [Monkeypox virus]
220
similar to VACV-COP-M2L, MPXV-ZAI96-O2L
Community Requests
Monkeypox virus
IDP90119
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_029
68449103
ankyrin-like protein [Monkeypox virus]
442
similar to VACV-COP-M1L, MPXV-ZAI96-O1L
Community Requests
1N11
16.3%
Monkeypox virus
IDP90121
(
show subtarget assignments
)
8
purified
MPXV_ZAI1979_005_031
68449105
ankyrin-like protein [Monkeypox virus]
284
similar to VACV-COP-K1L, MPXV-ZAI96-C1L
Community Requests
3KEA
94.7%
Monkeypox virus
IDP90122
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_032
68449106
serine protease inhibitor-likeprotein SP...
375
similar to VACV-COP-K2L, MPXV-ZAI96-C2L
Community Requests
3LW2
29.2%
Monkeypox virus
IDP90127
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_045
68449119
ser/thr kinase [Monkeypox virus]
439
similar to VACV-COP-F10L, MPXV-ZAI96-C16L
Community Requests
Monkeypox virus
IDP90128
(
show subtarget assignments
)
8
purified
MPXV_ZAI1979_005_060
68449134
myristylprotein [Monkeypox virus]
166
has N-myristyltransferase target MGxxxS/T/A, similar to VACV-COP-E7R, MPXV-ZAI96...
Community Requests
Monkeypox virus
IDP90142
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_188
68449259
unknown [Monkeypox virus]
149
similar to VACV-COP-B15R, MPXV-ZAI96-B13R
Community Requests
2VVY
93.3%
Monkeypox virus
IDP90429
(
show subtarget assignments
)
8
cloned
CT_860
3329334
hypothetical protein [Chlamydia trachoma...
493
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90129
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_084
68449158
myristylprotein [Monkeypox virus]
340
similar to VACV-COP-G9R, MPXV-ZAI96-G10R
Community Requests
Monkeypox virus
IDP90130
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_133
68449207
soluble myristylprotein [Monkeypox virus...
377
similar to VACV-COP-A16L, MPXV-ZAI96-A17L
Community Requests
Monkeypox virus
IDP90433
(
show subtarget assignments
)
8
cloned
CT_848
3329320
hypothetical protein [Chlamydia trachoma...
168
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90434
(
show subtarget assignments
)
8
cloned
CT_870
3329345
pmpF
Putative Outer Membrane Protein F [Chlam...
1034
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90133
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_159
68449233
CD47-like putative membrane protein [Mon...
277
similar to VACV-COP-A38L, MPXV-ZAI96-A40L
Community Requests
2JJS
11.6%
Monkeypox virus
IDP90132
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_155
68449229
unknown [Monkeypox virus]
176
similar to VACV-COP-A35R, MPXV-ZAI96-A37R
Community Requests
Monkeypox virus
IDP00175
(
show subtarget assignments
)
1
soluble
YPO1471
16121746
-
putative ATPase subunit of ATP-dependent...
880
Virulence
Phase 1: October 2007
1QVR
36.9%
Yersinia pestis
IDP90134
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_166
68449240
Toll/IL1-receptor [TIR]-like protein [Mo...
240
similar to VACV-COP-A46R, MPXV-ZAI96-A47R
Community Requests
Monkeypox virus
IDP90137
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_179
68449250
ankyrin-like protein [Monkeypox virus]
561
similar to VACV-COP-B4R, MPXV-ZAI96-B5R
Community Requests
1N11
11.2%
Monkeypox virus
IDP90140
(
show subtarget assignments
)
8
expressed
MPXV_ZAI1979_005_184
68449255
6kDa intracellular viral protein [Monkey...
221
similar to VACV-COP-B9R, MPXV-ZAI96-B10R
Community Requests
Monkeypox virus
IDP90138
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_181
68449252
ankyrin-like protein [Monkeypox virus]
119
similar to VACV-COP-B6R, MPXV-ZAI96-B7R
Community Requests
Monkeypox virus
IDP90139
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_182
68449253
bifunctional 21kDa precursor protein of ...
182
virulence, ER resident, similar to VACV-COP-B7R, N-terminal signal peptide, bifu...
Community Requests
Monkeypox virus
IDP90148
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_195
68449267
serine protease inhibitor-like SPI-1 pro...
71
similar to part of VACV-COP-C12L, MPXV-ZAI96-B19R
Community Requests
Monkeypox virus
IDP90164
(
show subtarget assignments
)
8
purified
CD1832
122973876
Putative chorismate biosynthesis-related...
337
Potential drug target. Shikimate pathway enzyme
Community Requests
1RZM
47.2%
Clostridium difficile
IDP01101
(
show subtarget assignments
)
1
expressed
GBAA_pXO1_0119
47566439
hypothetical protein GBAA_pXO1_0119
82
Virulence Associated Factor
Phase 2: March 2008
2K78
34.1%
Bacillus anthracis
IDP90506
(
show subtarget assignments
)
8
in_pdb
3PLX
Cj0296c
15791664
panD
aspartate alpha-decarboxylase [Campyloba...
126
Predicted Essential
Community Requests
3PLX
80.2%
Campylobacter jejuni
IDP90147
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_194
68449266
kelch-like protein [Monkeypox virus]
70
similar to CPXV-GRI-B19R, MPXV-ZAI96-B18R
Community Requests
2Q81
31.4%
Monkeypox virus
IDP90509
(
show subtarget assignments
)
8
purified
Cj0347
15791715
trpF
N-(5'phosphoribosyl)anthranilate isomera...
199
Predicted Essential
Community Requests
1DL3
31.4%
Campylobacter jejuni
IDP90144
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_189.5
68449261
bifunctional IL-1-beta-inhibitor/prevent...
126
contains IG fold, similar to VACV-WR-197, MPXV-ZAR_1979_005-184
Community Requests
1G0Y
27.8%
Monkeypox virus
IDP90145
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_192
68449264
IFN-alpha/beta-receptor-like secreted gl...
352
similar to VACV-COP-B19R, MPXV-ZAI96-B16R
Community Requests
3OQ3
83.2%
Monkeypox virus
IDP90150
(
show subtarget assignments
)
8
cloned
MPXV_ZAI1979_005_202
68449275
unknown [Monkeypox virus]
176
similar to CPXV-GRI-C2L, MPXV-ZAI96-N3R
Community Requests
Monkeypox virus
IDP90149
(
show subtarget assignments
)
8
soluble
MPXV_ZAI1979_005_195.5
68449268
serine protease inhibitor-like SPI-1 pro...
357
similar to part of VACV-COP-C12L, MPXV-ZAI96-B19R
Community Requests
1F0C
42%
Monkeypox virus
IDP00183
(
show subtarget assignments
)
1
cloned
YPO0613
16120939
-
putative permease protein
293
Virulence
Phase 1: October 2007
2R6G
22.5%
Yersinia pestis
IDP90163
(
show subtarget assignments
)
8
in_pdb
3JS3
CD2217
172044608
aroD
3-dehydroquinate dehydratase (3-dehydroq...
255
Potential drug target. Shikimate pathway enzyme
Community Requests
3JS3
100%
Clostridium difficile
IDP90162
(
show subtarget assignments
)
8
purified
CD1833
123174272
3-dehydroquinate synthase
354
Potential drug target. Shikimate pathway enzyme
Community Requests
3OKF
40.1%
Clostridium difficile
IDP90515
(
show subtarget assignments
)
8
in_pdb
3ULW
Cj0884
15792215
rpsO
30S ribosomal protein S15 [Campylobacter...
90
Predicted Essential
Community Requests
3ULW
100%
Campylobacter jejuni
IDP90517
(
show subtarget assignments
)
8
in_pdb
3UGS
Cj0824
15792162
uppS
undecaprenyl diphosphate synthase [Campy...
222
Predicted Essential
Community Requests
3UGS
100%
Campylobacter jejuni
IDP90518
(
show subtarget assignments
)
8
purified
Cj1404
15792722
hypothetical protein Cj1404 [Campylobact...
181
Predicted Essential
Community Requests
1KAM
30.2%
Campylobacter jejuni
IDP90165
(
show subtarget assignments
)
8
purified
CD1834
123174271
3-phosphoshikimate 1-carboxyvinyltransfe...
437
Potential drug target. Shikimate pathway enzyme
Community Requests
3NVS
32.5%
Clostridium difficile
IDP01166
(
show subtarget assignments
)
1
cloned
GBAA_pXO1_0190
47566502
hypothetical protein GBAA_pXO1_0190
410
Virulence Associated Factor
Phase 2: March 2008
Bacillus anthracis
IDP90166
(
show subtarget assignments
)
8
soluble
CD1837
126699446
aroE
shikimate dehydrogenase [Clostridium dif...
269
Potential drug target. Shikimate pathway enzyme
Community Requests
3FBT
42%
Clostridium difficile
IDP01109
(
show subtarget assignments
)
1
soluble
GBAA_pXO1_0148
47566460
hypothetical protein GBAA_pXO1_0148
150
Virulence Associated Factor
Phase 2: March 2008
3PMD
100%
Bacillus anthracis
IDP90223
(
show subtarget assignments
)
1
expressed
SA1226
15926974
Asd
Aspartate semialdehyde dehydrogenase Asd...
329
This enzyme participates in glycine, serine and threonine metabolism and lysine ...
January 2009
2YV3
43.4%
Staphylococcus aureus
IDP90222
(
show subtarget assignments
)
1
in_pdb
3H2Y
BAS4233
49187229
YqeH
GTP-binding protein YqeH, possibly invol...
368
YqeH is an essential GTP-binding protein. Depletion of YqeH induces an excess in...
January 2009
3H2Y
100%
Bacillus anthracis
IDP90248
(
show subtarget assignments
)
8
purified
BAS0467
49183495
acetylornithine deacetylase [Bacillus an...
426
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3PFO
27%
Bacillus anthracis
IDP90523
(
show subtarget assignments
)
8
in_pdb
3Q12
3Q10
YPO3402
16123551
panC
pantoate--beta-alanine ligase [Yersinia ...
284
Predicted Essential
Community Requests
3Q10
100%
Yersinia pestis
IDP90226
(
show subtarget assignments
)
1
selected
VC2428
9657003
conserved hypothetical protein [Vibrio c...
246
Conserved gene clusters with virulence associated genes. Conserved Protein; Pred...
January 2009
2OEZ
74.8%
Vibrio cholerae
IDP01169
(
show subtarget assignments
)
1
cloned
GBAA_pXO1_0146
47566458
atxA
transcriptional activator atxa, (pxo1-11...
475
Virulence Associated Factor
Phase 2: March 2008
3SQN
20.4%
Bacillus anthracis
IDP01167
(
show subtarget assignments
)
1
expressed
GBAA_pXO2_0060
47566729
capsule synthesis trans-acting positive ...
482
Virulence Associated Factor
Phase 2: March 2008
3SQN
22%
Bacillus anthracis
IDP01168
(
show subtarget assignments
)
1
expressed
GBAA_pXO2_0084
47566748
capsule synthesis trans-acting positive ...
483
Virulence Associated Factor
Phase 2: March 2008
3SQN
8.5%
Bacillus anthracis
IDP01174
(
show subtarget assignments
)
1
expressed
BA_2823
30257425
hypothetical protein BA_2823
375
Drug Target Function
Phase 2: March 2008
Bacillus anthracis
IDP90244
(
show subtarget assignments
)
8
expressed
YPO3053
218930098
dapE
succinyl-diaminopimelate desuccinylase [...
375
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3IC1
63.2%
Yersinia pestis
IDP90527
(
show subtarget assignments
)
8
cloned
YPO3179
16123341
pgpA
phosphatidylglycerophosphatase A [Yersin...
161
Predicted Essential
Community Requests
Yersinia pestis
IDP90528
(
show subtarget assignments
)
8
cloned
VCA1063
15601814
ornithine decarboxylase [Vibrio cholerae...
720
Predicted Essential
Community Requests
1ORD
59.1%
Vibrio cholerae
IDP00003
(
show subtarget assignments
)
1
expressed
GBAA_pXO1_0158
47566470
gerXC
spore germination protein xc, (pxo1-112)...
317
Drug Target Homolog
Phase 1: October 2007
Bacillus anthracis
IDP90267
(
show subtarget assignments
)
8
purified
TP_0326
3322602
Treponema pallidum subsp. pallidum str. ...
853
From requestor: The structural characterization of Tp0326 will be helpful in at ...
Community Requests
3EFC
11.6%
Treponema pallidum
IDP90251
(
show subtarget assignments
)
8
expressed
SF4034
56480493
argE
acetylornithine deacetylase [Shigella fl...
383
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2F7V
25.1%
Shigella flexneri
IDP90333
(
show subtarget assignments
)
8
soluble
CT_606.1
3522903
hypothetical protein [Chlamydia trachoma...
79
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00196
(
show subtarget assignments
)
1
cloned
YPO1051
16121351
-
putative membrane protein
451
Virulence
Phase 1: October 2007
2ZPL
13.5%
Yersinia pestis
IDP90254
(
show subtarget assignments
)
8
selected
AAK67494
21263110
ie1
IE1 protein [Human herpesvirus 6]
1078
(From requester) The IE1 protein of HHV-6, one of the first viral proteins synth...
Community Requests
Human herpesvirus
IDP00197
(
show subtarget assignments
)
1
purified
YPO1233
16121519
-
putative prophage repressor protein
240
Similar to Essential SALTY
Phase 1: October 2007
3BDN
46.2%
Yersinia pestis
IDP90253
(
show subtarget assignments
)
8
purified
SAR1776
49483939
pyk
pyruvate kinase [Staphylococcus aureus s...
585
(From requester) Potential drug target
Community Requests
3T05
100%
Staphylococcus aureus
IDP00198
(
show subtarget assignments
)
1
cloned
YPO1367
16121647
-
conserved hypothetical protein
106
Similar to Essential SALTY
Phase 1: October 2007
1MBU
84.9%
Yersinia pestis
IDP90276
(
show subtarget assignments
)
8
cloned
TGME49_032600
211965793
patatin-like phospholipase domain-contai...
664
Signature-tagged mutagenesis (STM) has identified this patatin-like phospholipas...
Community Requests
Toxoplasma gondii
IDP90275
(
show subtarget assignments
)
8
selected
TGME49_030450
211965620
GMP synthase, putative [Toxoplasma gondi...
569
Guanosine monophosphate synthetase is essential for the synthesis of GMP in puri...
Community Requests
1GPM
51%
Toxoplasma gondii
IDP90539
(
show subtarget assignments
)
8
purified
VC2708
15642702
gmk
guanylate kinase [Vibrio cholerae O1 bio...
229
Predicted Essential
Community Requests
1S96
59.8%
Vibrio cholerae
IDP90271
(
show subtarget assignments
)
8
in_pdb
3M5R
3M8A
ACP44186
227977167
NS1
nonstructural protein 1 [Influenza A vir...
219
swine flu virus
Community Requests
3F5T
79.9%
Influenza A
IDP90274
(
show subtarget assignments
)
8
selected
TGME49_015260
211968509
carbamoyl phosphate synthetase II [Toxop...
1699
Mutation of the rate-limiting enzyme carbamoyl phosphate synthetase II (CPSII) d...
Community Requests
1A9X
27.1%
Toxoplasma gondii
IDP90272
(
show subtarget assignments
)
8
cloned
TGME49_111670
211962063
hypothetical protein TGME49_111670 [Toxo...
440
Unpublished data from signature-tagged mutagenesis (STM) has identified this sur...
Community Requests
Toxoplasma gondii
IDP90273
(
show subtarget assignments
)
8
cloned
TGME49_013900
211968791
regulator of chromosome condensation, pu...
1155
Signature-tagged mutagenesis (STM) has identified the regulator of chromosome co...
Community Requests
3MVD
11.1%
Toxoplasma gondii
IDP90596
(
show subtarget assignments
)
8
cloned
Cj1234
15792558
glyS
glycyl-tRNA synthetase subunit beta [Cam...
664
Predicted Essential
Community Requests
Campylobacter jejuni
IDP90595
(
show subtarget assignments
)
8
expressed
YPO2298
16122522
phoA
alkaline phosphatase [Yersinia pestis CO...
481
Predicted Essential
Community Requests
1B8J
70.7%
Yersinia pestis
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