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Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
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1
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8
Keyword:
Type Keyword
Stage:
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cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Remove Filters
Download data as tab-separated value (TSV) file
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CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90338
(
show subtarget assignments
)
8
cloned
CT087
15604806
malQ
4-alpha-glucanotransferase [Chlamydia tr...
527
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2X1I
25.2%
Chlamydia trachomatis
IDP90342
(
show subtarget assignments
)
8
expressed
CT155
15604874
phospholipase D endonuclease superfamily...
313
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90341
(
show subtarget assignments
)
8
expressed
CT049
15604768
hypothetical protein CT049 [Chlamydia tr...
490
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90624
(
show subtarget assignments
)
8
cloned
Cj0718
15792067
dnaE
DNA polymerase III subunit alpha [Campyl...
1200
Predicted Essential
Community Requests
2HPI
37%
Campylobacter jejuni
IDP00205
(
show subtarget assignments
)
1
cloned
YPO1705
16121965
-
tail-specific protease precursor
690
Drug target motif; Conserved; Proteomics evidence (Cytoplasmid or periplasmic); ...
Phase 1: October 2007
1FC6
15.8%
Yersinia pestis
IDP90340
(
show subtarget assignments
)
8
expressed
CT_696
6578111
hypothetical protein [Chlamydia trachoma...
392
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90343
(
show subtarget assignments
)
8
expressed
CT148
15604867
mhpA
FAD-dependent monooxygenase [Chlamydia t...
507
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90347
(
show subtarget assignments
)
8
soluble
CT205
15604925
pfkA_1
diphosphate--fructose-6-phosphate 1-phos...
553
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1KZH
36.9%
Chlamydia trachomatis
IDP90344
(
show subtarget assignments
)
8
cloned
CT105
15604824
hypothetical protein CT105 [Chlamydia tr...
656
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90345
(
show subtarget assignments
)
8
cloned
CT157
15604876
phospholipase D endonuclease superfamily...
404
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1BYR
8.9%
Chlamydia trachomatis
IDP90348
(
show subtarget assignments
)
8
expressed
CT166
15604885
hypothetical protein CT166 [Chlamydia tr...
639
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3SRZ
15.6%
Chlamydia trachomatis
IDP90351
(
show subtarget assignments
)
8
cloned
CT165
15604884
hypothetical protein CT165 [Chlamydia tr...
148
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90350
(
show subtarget assignments
)
8
cloned
CT456
15605183
hypothetical protein CT456 [Chlamydia tr...
1005
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90349
(
show subtarget assignments
)
8
expressed
CT461
15605188
yaeI
phosphohydrolase [Chlamydia trachomatis ...
329
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90358
(
show subtarget assignments
)
8
expressed
CT273
15604994
hypothetical protein CT273 [Chlamydia tr...
188
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP01531
(
show subtarget assignments
)
1
in_pdb
3EFB
SF4094
56384059
sorC
probable sor-operon regulator [Shigella ...
315
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 3: June 2008
2W48
86.3%
Shigella flexneri
IDP90384
(
show subtarget assignments
)
8
purified
CT_360
3328783
hypothetical protein [Chlamydia trachoma...
208
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90636
(
show subtarget assignments
)
8
purified
Cj0432c
15791799
murD
UDP-N-acetylmuramoyl-L-alanyl-D-glutamat...
402
Predicted Essential
Community Requests
1E0D
27.6%
Campylobacter jejuni
IDP90357
(
show subtarget assignments
)
8
selected
CBU_0666
29654004
dapE
succinyl-diaminopimelate desuccinylase [...
374
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3IC1
50.5%
Coxiella burnetii
IDP90639
(
show subtarget assignments
)
8
cloned
Cj0771c
15792109
lipoprotein, NLPA family [Campylobacter ...
256
Predicted Essential
Community Requests
3TQW
39.8%
Campylobacter jejuni
IDP90356
(
show subtarget assignments
)
8
cloned
CT080
15604799
ltuB
late transcription unit B protein [Chlam...
97
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90355
(
show subtarget assignments
)
8
in_pdb
3N08
CT736
15605469
ybcL
hypothetical protein CT736 [Chlamydia tr...
150
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3N08
100%
Chlamydia trachomatis
IDP01530
(
show subtarget assignments
)
1
in_pdb
3EFV
3ETF
STM1524
16764869
yneI
putative succinate-semialdehyde dehydrog...
462
It is an essential gene in Salmonella which is important in energy metabolism.
Phase 3: June 2008
3EFV
100%
Salmonella enterica
IDP90360
(
show subtarget assignments
)
8
purified
CT_016
3328405
hypothetical protein [Chlamydia trachoma...
242
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90359
(
show subtarget assignments
)
8
cloned
CT794.1
15605528
hypothetical protein CT794.1 [Chlamydia ...
95
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90644
(
show subtarget assignments
)
8
purified
STM1201
16764556
holB
DNA polymerase III subunit delta' [Salmo...
334
Predicted Essential
Community Requests
1A5T
79%
Salmonella enterica
IDP90361
(
show subtarget assignments
)
8
cloned
CT_021
3328411
hypothetical protein [Chlamydia trachoma...
247
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP01519
(
show subtarget assignments
)
1
purified
VC2149
15642148
hypothetical protein VC2149
95
Drug Target Function
Phase 2: March 2008
3KE2
43.2%
Vibrio cholerae
IDP90362
(
show subtarget assignments
)
8
soluble
CT_053
3328445
hypothetical protein [Chlamydia trachoma...
148
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90647
(
show subtarget assignments
)
8
cloned
VC2685
15642680
metF
5,10-methylenetetrahydrofolate reductase...
304
Predicted Essential
Community Requests
1ZP3
75.3%
Vibrio cholerae
IDP01540
(
show subtarget assignments
)
1
in_pdb
3EC6
GBAA0418
47525694
general stress protein 26 [Bacillus anth...
138
CONSERVED
Phase 3: June 2008
3EC6
100%
Bacillus anthracis
IDP90368
(
show subtarget assignments
)
8
expressed
CT_143
3328543
hypothetical protein [Chlamydia trachoma...
280
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90367
(
show subtarget assignments
)
8
expressed
CT_144
3328544
hypothetical protein [Chlamydia trachoma...
285
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90366
(
show subtarget assignments
)
8
expressed
CT_142
3328542
hypothetical protein [Chlamydia trachoma...
285
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90371
(
show subtarget assignments
)
8
cloned
CT_109
3328506
CHLPS hypothetical protein [Chlamydia tr...
262
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90653
(
show subtarget assignments
)
8
soluble
VC2524
15642520
3-deoxy-D-manno-octulosonate 8-phosphate...
185
Predicted Essential
Community Requests
3N07
99.5%
Vibrio cholerae
IDP90369
(
show subtarget assignments
)
8
cloned
CT_181
3328585
hypothetical protein [Chlamydia trachoma...
236
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90370
(
show subtarget assignments
)
8
soluble
CT_263
3328675
hypothetical protein [Chlamydia trachoma...
196
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00222
(
show subtarget assignments
)
1
cloned
YPO3049
16123226
-
putative binding protein-dependent trans...
589
Virulence
Phase 1: October 2007
3DKN
15.3%
Yersinia pestis
IDP90373
(
show subtarget assignments
)
8
expressed
CT_191
3328596
hypothetical protein [Chlamydia trachoma...
116
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00223
(
show subtarget assignments
)
1
purified
YPO3054
16123231
-
putative carboxypeptidase
225
Virulence
Phase 1: October 2007
Yersinia pestis
IDP90374
(
show subtarget assignments
)
8
expressed
CT_338
3328758
hypothetical protein [Chlamydia trachoma...
153
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90377
(
show subtarget assignments
)
8
purified
CT_274
3328687
hypothetical protein [Chlamydia trachoma...
139
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3KD7
15.1%
Chlamydia trachomatis
IDP90381
(
show subtarget assignments
)
8
cloned
CT_309
3328725
hypothetical protein [Chlamydia trachoma...
266
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90378
(
show subtarget assignments
)
8
cloned
CT_303
3328719
hypothetical protein [Chlamydia trachoma...
171
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90379
(
show subtarget assignments
)
8
cloned
CT_330
3328749
hypothetical protein [Chlamydia trachoma...
90
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90101
(
show subtarget assignments
)
8
purified
STM2287
16765614
sseL
deubiquitinase [Salmonella typhimurium L...
317
SseL, is a ubiquitin isopeptidase that plays a critical role in the virulence an...
Community Requests
Salmonella enterica
IDP90392
(
show subtarget assignments
)
8
purified
CT_584
3329027
hypothetical protein [Chlamydia trachoma...
183
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3Q9D
83.1%
Chlamydia trachomatis
IDP90089
(
show subtarget assignments
)
8
expressed
ZZZ_0005
600
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90416
(
show subtarget assignments
)
8
purified
CT_538
3328976
hypothetical protein [Chlamydia trachoma...
238
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90387
(
show subtarget assignments
)
8
expressed
CT_372
3328796
hypothetical protein [Chlamydia trachoma...
442
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90386
(
show subtarget assignments
)
8
expressed
CT_355
3328776
hypothetical protein [Chlamydia trachoma...
353
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90388
(
show subtarget assignments
)
8
cloned
CT_619
3329065
hypothetical protein [Chlamydia trachoma...
877
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90389
(
show subtarget assignments
)
8
cloned
CT_384
3328809
hypothetical protein [Chlamydia trachoma...
539
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90394
(
show subtarget assignments
)
8
expressed
CT_560
3329001
hypothetical protein [Chlamydia trachoma...
278
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90393
(
show subtarget assignments
)
8
cloned
CT_567
3329008
hypothetical protein [Chlamydia trachoma...
174
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90395
(
show subtarget assignments
)
8
cloned
CT_573
3329014
hypothetical protein [Chlamydia trachoma...
409
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90396
(
show subtarget assignments
)
8
soluble
CT_552
3328992
hypothetical protein [Chlamydia trachoma...
135
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90400
(
show subtarget assignments
)
8
purified
CT_566
3329007
hypothetical protein [Chlamydia trachoma...
330
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90668
(
show subtarget assignments
)
8
purified
Cj0206
15791593
thrS
threonyl-tRNA synthetase [Campylobacter ...
602
Predicted Essential
Community Requests
1QF6
43%
Campylobacter jejuni
IDP90398
(
show subtarget assignments
)
8
soluble
CT_577
3329019
hypothetical protein [Chlamydia trachoma...
119
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90399
(
show subtarget assignments
)
8
expressed
CT_569
3329010
gspG
predicted OMP [Chlamydia trachomatis D/U...
109
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00251
(
show subtarget assignments
)
1
cloned
MVEVgp1
9633623
Murray Valley encephalitis Envelope prot...
407
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3P54
78.1%
Murray Valley
IDP90082
(
show subtarget assignments
)
8
purified
P03493.2
85681917
RecName: Full=Matrix protein 2; AltName:...
109
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2KJ1
64.2%
Influenza B
IDP00252
(
show subtarget assignments
)
1
purified
130516
St. Louis encephalitis virus Envelope pr...
407
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
2I69
70.5%
St. Louis
IDP90408
(
show subtarget assignments
)
8
expressed
CT_631
3329079
hypothetical protein [Chlamydia trachoma...
84
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00253
(
show subtarget assignments
)
1
purified
YFVgp1
9627245
Yellow fever virus Envelope protein
399
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1P58
43.8%
Yellow fever
IDP90404
(
show subtarget assignments
)
8
cloned
CT_654
3329104
hypothetical protein [Chlamydia trachoma...
162
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00254
(
show subtarget assignments
)
1
in_pdb
3P54
13272205
Japanese encephalitis virus Envelope pro...
406
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3P54
98.3%
Japanese encephalitis
IDP90405
(
show subtarget assignments
)
8
cloned
CT_651
3329100
hypothetical protein [Chlamydia trachoma...
608
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00255
(
show subtarget assignments
)
1
selected
NP_041725:276-677
9627243
CFA
Cell fusing agent virus Envelope protein...
402
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3C5X
15.2%
Cell fusing
IDP90409
(
show subtarget assignments
)
8
purified
CT_667
3329118
hypothetical protein [Chlamydia trachoma...
149
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00256
(
show subtarget assignments
)
1
expressed
RBVgp1
21397175
Rio Bravo bat virus Envelope protein
395
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1URZ
43.2%
Rio Bravo
IDP90678
(
show subtarget assignments
)
8
purified
Cj0766c
15792104
tdk
thymidylate kinase [Campylobacter jejuni...
192
Predicted Essential
Community Requests
3HJN
33.8%
Campylobacter jejuni
IDP00257
(
show subtarget assignments
)
1
purified
MODVgp1
20177456
Modoc virus Envelope protein
393
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1SVB
41%
Modoc virus
IDP90410
(
show subtarget assignments
)
8
purified
CT_663
3329114
hypothetical protein [Chlamydia trachoma...
133
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00258
(
show subtarget assignments
)
1
purified
MMLVgp1
22550316
Montana myotis leukoencephalitis Envelop...
395
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1URZ
43.6%
Montana myotis
IDP90411
(
show subtarget assignments
)
8
expressed
CT_647
3329096
hypothetical protein [Chlamydia trachoma...
192
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00259
(
show subtarget assignments
)
1
crystallized
CPXV018
30844336
CPXV229 CDS
OMCP protein Cowpox virus
171
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
Cowpox virus
IDP90007
(
show subtarget assignments
)
8
cloned
Z4378
12517596
qseC
quorum sensing Escherichia coli regulato...
449
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3JZ3
47%
Escherichia coli
IDP00260
(
show subtarget assignments
)
1
purified
AF380138
17529967
N3R
N3R [Monkeypox virus]
176
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
Monkeypox virus
IDP90000
(
show subtarget assignments
)
8
cloned
FTT1352
56708408
hypothetical protein FTT1352
383
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Francisella tularensis
IDP90083
(
show subtarget assignments
)
8
cloned
ZP_01795671
145640077
hypothetical protein CGSHiII_00664 [Haem...
219
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
35.6%
Haemophilus influenzae
IDP90001
(
show subtarget assignments
)
8
cloned
FTT0094c
56603762
qseC
sensor histidine kinase
475
Drug Target (Community Request)
Community Requests
3A0R
15.8%
Francisella tularensis
IDP90088
(
show subtarget assignments
)
8
soluble
ZZZ_0004
140
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90087
(
show subtarget assignments
)
8
cloned
ZZZ_0003
168
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90005
(
show subtarget assignments
)
8
soluble
Z4377
12517595
qseB
quorum sensing Escherichia coli regulato...
219
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3Q9S
41.1%
Escherichia coli
IDP90092
(
show subtarget assignments
)
8
purified
ZZZ_0008
155
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP00266
(
show subtarget assignments
)
1
cloned
AAX48017_114-279
61652905
N/A
Premembrane/Membrane protein (prM)
166
Very hydrophilic; 6 Cys residues form intramolecular disulfide bonds
Phase 3: June 2008
3C5X
57.2%
Dengue virus
N/A
IDP90081
(
show subtarget assignments
)
8
cloned
ABD79034.1
89892477
M2
matrix protein 2 [Influenza A virus (A/U...
96
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2L0J
42.7%
Influenza A
IDP90003
(
show subtarget assignments
)
8
purified
FTT1103
56708183
conserved hypothetical lipoprotein
365
(Community Request)
Community Requests
3GYK
12.3%
Francisella tularensis
IDP90422
(
show subtarget assignments
)
8
cloned
CT_471
3328905
hypothetical protein [Chlamydia trachoma...
200
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90421
(
show subtarget assignments
)
8
expressed
CT_433
3328864
hypothetical protein [Chlamydia trachoma...
223
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90093
(
show subtarget assignments
)
8
expressed
ZZZ_0009
99
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90086
(
show subtarget assignments
)
8
expressed
ZZZ_0002
492
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90425
(
show subtarget assignments
)
8
expressed
CT_547
3328986
hypothetical protein [Chlamydia trachoma...
318
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3QKY
11.9%
Chlamydia trachomatis
IDP90098
(
show subtarget assignments
)
8
purified
ZZZ_0014
196
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90099
(
show subtarget assignments
)
8
cloned
ZZZ_0015
1137
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90698
(
show subtarget assignments
)
8
purified
Cj1531
15792839
dapF
diaminopimelate epimerase [Campylobacter...
249
Predicted Essential
Community Requests
3EJX
30.2%
Campylobacter jejuni
IDP90697
(
show subtarget assignments
)
8
cloned
Cj0098
15791486
fmt
methionyl-tRNA formyltransferase [Campyl...
305
Predicted Essential
Community Requests
3R8X
38%
Campylobacter jejuni
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