Home
Target List
Selection
Community Requests
Clones
XML files
Diffraction Images
Progress
Homolog Search
Clustering
Statistics
News
Help
Log In
Consortium
Overview
Investigators
Experiments
X-ray Structures
NMR Structures
Electronic Structure Description
Publications
Resources
Clustering
Related Sites
Progress
Collaborators
Basecamp
Contact Us
Log In
Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
In
IDP#
NCBI GI
LOCUS TAG
Search
Page 6 of 60, showing 100 records out of 5960 total, starting on record 501
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP00272
(
show subtarget assignments
)
1
in_pdb
3IRC
3EGP
AF180817_281-775
7329982
N/A
Envelope (E)
495
Contains receptor binding sites and fusogenic domain; also contains 12 Cys resid...
Phase 1: October 2007
3G7T
78.8%
Dengue virus
N/A
IDP90224
(
show subtarget assignments
)
8
in_pdb
3I0U
CP0010
31983551
OspF
Shigella OspF effector
239
Shigella OspF effector
Community Requests
3I0U
90.8%
Shigella flexneri
IDP90227
(
show subtarget assignments
)
0
work_stopped
BAS1428
49184445
-
Histidinol-phosphate aminotransferase (E...
370
Histidinol phosphate aminotransferase (EC 2.6.1.9) is a key enzyme on the histid...
January 2009
3FFH
46.2%
Bacillus anthracis
IDP90244
(
show subtarget assignments
)
8
expressed
YPO3053
218930098
dapE
succinyl-diaminopimelate desuccinylase [...
375
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3IC1
63.2%
Yersinia pestis
IDP90242
(
show subtarget assignments
)
8
expressed
SA1814
15927582
succinyl-diaminopimelate desuccinylase [...
407
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3TX8
25.5%
Staphylococcus aureus
IDP90588
(
show subtarget assignments
)
8
cloned
Q9KLX5
23821639
RecName: Full=GTP cyclohydrolase 1; AltN...
217
Predicted Essential
Community Requests
1FBX
70.5%
Vibrio cholerae
IDP90245
(
show subtarget assignments
)
8
selected
SF2514
24113800
dapE
succinyl-diaminopimelate desuccinylase [...
375
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3IC1
61.6%
Shigella flexneri
IDP90591
(
show subtarget assignments
)
8
in_pdb
3N9I
YPO0157
16120500
trpS
tryptophanyl-tRNA synthetase [Yersinia p...
346
Predicted Essential
Community Requests
3N9I
100%
Yersinia pestis
IDP00276
(
show subtarget assignments
)
1
soluble
AAA99437_115-280
323469
N/A
Premembrane/Membrane protein (prM)
166
Very hydrophilic; 6 Cys residues form intramolecular disulfide bonds
Phase 3: June 2008
3C5X
56%
Dengue virus
N/A
IDP90589
(
show subtarget assignments
)
8
soluble
VC0296
15640324
acetyl-CoA carboxylase [Vibrio cholerae ...
196
Predicted Essential
Community Requests
1A6X
37.2%
Vibrio cholerae
IDP00002
(
show subtarget assignments
)
1
expressed
GBAA_pXO1_0079
47566400
-
surface layer protein, (pxo1-54)
404
Drug Target Homolog
Phase 1: October 2007
3PYW
14.4%
Bacillus anthracis
IDP90306
(
show subtarget assignments
)
8
cloned
CT_694
3329148
hypothetical protein [Chlamydia trachoma...
323
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP01168
(
show subtarget assignments
)
1
expressed
GBAA_pXO2_0084
47566748
capsule synthesis trans-acting positive ...
483
Virulence Associated Factor
Phase 2: March 2008
3SQN
8.5%
Bacillus anthracis
IDP90273
(
show subtarget assignments
)
8
cloned
TGME49_013900
211968791
regulator of chromosome condensation, pu...
1155
Signature-tagged mutagenesis (STM) has identified the regulator of chromosome co...
Community Requests
3MVD
11.1%
Toxoplasma gondii
IDP90274
(
show subtarget assignments
)
8
selected
TGME49_015260
211968509
carbamoyl phosphate synthetase II [Toxop...
1699
Mutation of the rate-limiting enzyme carbamoyl phosphate synthetase II (CPSII) d...
Community Requests
1A9X
27.1%
Toxoplasma gondii
IDP90301
(
show subtarget assignments
)
8
selected
TGME49_025290
211963866
nucleoside-triphosphatase, putative [Tox...
642
The T. gondii nucleoside triphosphate hydrolases (NTPase) are ecto ATPases with ...
Community Requests
3AGR
38.6%
Toxoplasma gondii
IDP00280
(
show subtarget assignments
)
1
purified
AAX48017_51-545
604449
N/A
Envelope (E)
495
Contains receptor binding sites and fusogenic domain; also contains 12 Cys resid...
Phase 3: June 2008
3UAJ
79.2%
Dengue virus
N/A
IDP90302
(
show subtarget assignments
)
0
work_stopped
BB_0420
2688313
sensory transduction histidine kinase, p...
1494
Mutational studies suggest that Hk1 is required for the survival of the Lyme dis...
Community Requests
3A0R
5.6%
Borrelia burgdorferi
IDP90313
(
show subtarget assignments
)
8
cloned
CT_713
3329169
ompB
Outer Membrane Protein Analog [Chlamydia...
340
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90308
(
show subtarget assignments
)
8
cloned
CT_700
3329154
hypothetical protein [Chlamydia trachoma...
441
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1NA0
6.3%
Chlamydia trachomatis
IDP90307
(
show subtarget assignments
)
8
cloned
CT_695
3329149
hypothetical protein [Chlamydia trachoma...
398
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90604
(
show subtarget assignments
)
8
in_pdb
3Q0I
VC0045
15640077
fmt
methionyl-tRNA formyltransferase [Vibrio...
315
Predicted Essential
Community Requests
3Q0I
100%
Vibrio cholerae
IDP00300
(
show subtarget assignments
)
1
cloned
CBU_1153
548
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 2: March 2008
1GXB
10.4%
Coxiella burnetii
IDP90309
(
show subtarget assignments
)
8
cloned
CT_702
3329157
hypothetical protein [Chlamydia trachoma...
175
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP00301
(
show subtarget assignments
)
1
expressed
CBU_0983
291
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 2: March 2008
3NVT
10.7%
Coxiella burnetii
IDP90310
(
show subtarget assignments
)
8
expressed
CT_716
3329172
hypothetical protein [Chlamydia trachoma...
121
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90317
(
show subtarget assignments
)
8
cloned
CT_724
3329181
hypothetical protein [Chlamydia trachoma...
174
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90327
(
show subtarget assignments
)
8
cloned
CT_590
3329033
hypothetical protein [Chlamydia trachoma...
954
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90316
(
show subtarget assignments
)
8
cloned
CT_743
3329202
hctA
Histone-Like Developmental Protein [Chla...
125
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90315
(
show subtarget assignments
)
8
cloned
CT_744
3329204
CHLTR possible phosphoprotein [Chlamydia...
821
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90319
(
show subtarget assignments
)
8
cloned
CT_753
3329214
hypothetical protein [Chlamydia trachoma...
74
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90320
(
show subtarget assignments
)
8
cloned
CT_779
3329243
hypothetical protein [Chlamydia trachoma...
229
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90318
(
show subtarget assignments
)
8
purified
CT_718
3329174
hypothetical protein [Chlamydia trachoma...
174
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90616
(
show subtarget assignments
)
8
selected
VC1054
15641067
DNA polymerase III subunits gamma and ta...
692
Predicted Essential
Community Requests
1JR3
34.5%
Vibrio cholerae
IDP90534
(
show subtarget assignments
)
8
cloned
Cj1071
15792396
ssb
single-strand DNA-binding protein [Campy...
183
Predicted Essential
Community Requests
2VW9
35.5%
Campylobacter jejuni
IDP90397
(
show subtarget assignments
)
8
purified
CT_583
3329026
gp6D
CHLTR Plasmid Paralog [Chlamydia trachom...
263
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90325
(
show subtarget assignments
)
8
cloned
CT089
15604808
lcrE
low calcium response E [Chlamydia tracho...
421
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2VJ4
13.3%
Chlamydia trachomatis
IDP90620
(
show subtarget assignments
)
8
expressed
VC0275
15640304
phosphoribosylamine--glycine ligase [Vib...
429
Predicted Essential
Community Requests
1GSO
77.9%
Vibrio cholerae
IDP90322
(
show subtarget assignments
)
8
expressed
CT_809
3329276
hypothetical protein [Chlamydia trachoma...
103
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90321
(
show subtarget assignments
)
8
purified
CT_795
3329261
hypothetical protein [Chlamydia trachoma...
163
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90323
(
show subtarget assignments
)
8
cloned
CT082
15604801
hypothetical protein CT082 [Chlamydia tr...
560
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90324
(
show subtarget assignments
)
8
expressed
CT088
15604807
sycE
secretion chaperone [Chlamydia trachomat...
146
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90329
(
show subtarget assignments
)
8
cloned
CT_548
3328987
hypothetical protein [Chlamydia trachoma...
194
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90339
(
show subtarget assignments
)
8
cloned
CT050
15604769
hypothetical protein CT050 [Chlamydia tr...
536
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3H0G
10.8%
Chlamydia trachomatis
IDP90628
(
show subtarget assignments
)
8
purified
VC0760
15640779
hisS
histidyl-tRNA synthetase [Vibrio cholera...
422
Predicted Essential
Community Requests
1KMM
74.5%
Vibrio cholerae
IDP90629
(
show subtarget assignments
)
8
cloned
Cj0896c
15792226
pheT
phenylalanyl-tRNA synthetase subunit bet...
773
Predicted Essential
Community Requests
2RHS
28.6%
Campylobacter jejuni
IDP01167
(
show subtarget assignments
)
1
expressed
GBAA_pXO2_0060
47566729
capsule synthesis trans-acting positive ...
482
Virulence Associated Factor
Phase 2: March 2008
3SQN
22%
Bacillus anthracis
IDP90328
(
show subtarget assignments
)
8
cloned
CT_413
3328841
pmpB
Putative outer membrane protein B [Chlam...
1751
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90633
(
show subtarget assignments
)
8
cloned
VC1971
15641973
O-succinylbenzoic acid--CoA ligase [Vibr...
476
Predicted Essential
Community Requests
2QVX
27.9%
Vibrio cholerae
IDP90634
(
show subtarget assignments
)
8
purified
YPO3403
16123552
panD
aspartate alpha-decarboxylase [Yersinia ...
126
Predicted Essential
Community Requests
1PPY
78.6%
Yersinia pestis
IDP90331
(
show subtarget assignments
)
8
selected
CT_874
3329350
pmpI
Putative Outer Membrane Protein I [Chlam...
878
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90330
(
show subtarget assignments
)
8
expressed
CT_602
3329047
hypothetical protein [Chlamydia trachoma...
130
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90332
(
show subtarget assignments
)
8
cloned
CT_421.1
3522895
hypothetical protein [Chlamydia trachoma...
53
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90338
(
show subtarget assignments
)
8
cloned
CT087
15604806
malQ
4-alpha-glucanotransferase [Chlamydia tr...
527
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2X1I
25.2%
Chlamydia trachomatis
IDP90334
(
show subtarget assignments
)
8
cloned
CT_421.2
3522896
hypothetical protein [Chlamydia trachoma...
53
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90337
(
show subtarget assignments
)
8
expressed
CT_623
6578109
CHLPN 76kDa Homolog [Chlamydia trachomat...
432
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90336
(
show subtarget assignments
)
8
cloned
CT_849.1
3522913
hypothetical protein [Chlamydia trachoma...
62
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90335
(
show subtarget assignments
)
8
soluble
CT_652.1
3522906
hypothetical protein [Chlamydia trachoma...
59
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90340
(
show subtarget assignments
)
8
expressed
CT_696
6578111
hypothetical protein [Chlamydia trachoma...
392
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90341
(
show subtarget assignments
)
8
expressed
CT049
15604768
hypothetical protein CT049 [Chlamydia tr...
490
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90342
(
show subtarget assignments
)
8
expressed
CT155
15604874
phospholipase D endonuclease superfamily...
313
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90350
(
show subtarget assignments
)
8
cloned
CT456
15605183
hypothetical protein CT456 [Chlamydia tr...
1005
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90345
(
show subtarget assignments
)
8
cloned
CT157
15604876
phospholipase D endonuclease superfamily...
404
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1BYR
8.9%
Chlamydia trachomatis
IDP90344
(
show subtarget assignments
)
8
cloned
CT105
15604824
hypothetical protein CT105 [Chlamydia tr...
656
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90346
(
show subtarget assignments
)
8
cloned
CT344
15605067
lon
ATP-dependent protease La [Chlamydia tra...
819
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3M6A
30.8%
Chlamydia trachomatis
IDP90347
(
show subtarget assignments
)
8
soluble
CT205
15604925
pfkA_1
diphosphate--fructose-6-phosphate 1-phos...
553
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1KZH
36.9%
Chlamydia trachomatis
IDP90352
(
show subtarget assignments
)
8
expressed
CT262
15604983
hypothetical protein CT262 [Chlamydia tr...
256
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2CZL
32%
Chlamydia trachomatis
IDP90355
(
show subtarget assignments
)
8
in_pdb
3N08
CT736
15605469
ybcL
hypothetical protein CT736 [Chlamydia tr...
150
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3N08
100%
Chlamydia trachomatis
IDP90351
(
show subtarget assignments
)
8
cloned
CT165
15604884
hypothetical protein CT165 [Chlamydia tr...
148
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90649
(
show subtarget assignments
)
8
cloned
Cj1104
15792429
4-diphosphocytidyl-2-C-methyl-D-erythrit...
255
Predicted Essential
Community Requests
2V2Q
29%
Campylobacter jejuni
IDP90354
(
show subtarget assignments
)
8
purified
CT672
15605405
fliN
type III secretion system protein [Chlam...
373
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90652
(
show subtarget assignments
)
8
expressed
Cj0897c
15792227
pheS
phenylalanyl-tRNA synthetase subunit alp...
330
Predicted Essential
Community Requests
3PCO
50.6%
Campylobacter jejuni
IDP90353
(
show subtarget assignments
)
8
expressed
CT198
15604918
oppA_3
oligopeptide binding protein [Chlamydia ...
518
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1UIU
25.5%
Chlamydia trachomatis
IDP90654
(
show subtarget assignments
)
8
expressed
YPO0474
16120803
ribF
bifunctional riboflavin kinase/FMN adeny...
312
Predicted Essential
Community Requests
1MRZ
32.1%
Yersinia pestis
IDP90362
(
show subtarget assignments
)
8
soluble
CT_053
3328445
hypothetical protein [Chlamydia trachoma...
148
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90375
(
show subtarget assignments
)
8
purified
CT_296
3328711
hypothetical protein [Chlamydia trachoma...
155
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3QH6
98.1%
Chlamydia trachomatis
IDP90396
(
show subtarget assignments
)
8
soluble
CT_552
3328992
hypothetical protein [Chlamydia trachoma...
135
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90661
(
show subtarget assignments
)
8
purified
Q9KSL9
33301117
RecName: Full=Nicotinate-nucleotide--dim...
341
Predicted Essential
Community Requests
1J33
45.2%
Vibrio cholerae
IDP90272
(
show subtarget assignments
)
8
cloned
TGME49_111670
211962063
hypothetical protein TGME49_111670 [Toxo...
440
Unpublished data from signature-tagged mutagenesis (STM) has identified this sur...
Community Requests
Toxoplasma gondii
IDP90271
(
show subtarget assignments
)
8
in_pdb
3M5R
3M8A
ACP44186
227977167
NS1
nonstructural protein 1 [Influenza A vir...
219
swine flu virus
Community Requests
3F5T
79.9%
Influenza A
IDP90360
(
show subtarget assignments
)
8
purified
CT_016
3328405
hypothetical protein [Chlamydia trachoma...
242
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90359
(
show subtarget assignments
)
8
cloned
CT794.1
15605528
hypothetical protein CT794.1 [Chlamydia ...
95
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90363
(
show subtarget assignments
)
8
cloned
CT_066
3328460
hypothetical protein [Chlamydia trachoma...
158
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90367
(
show subtarget assignments
)
8
expressed
CT_144
3328544
hypothetical protein [Chlamydia trachoma...
285
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90364
(
show subtarget assignments
)
8
expressed
CT_083
3328478
hypothetical protein [Chlamydia trachoma...
160
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90365
(
show subtarget assignments
)
8
cloned
CT_102
3328499
hypothetical protein [Chlamydia trachoma...
153
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90368
(
show subtarget assignments
)
8
expressed
CT_143
3328543
hypothetical protein [Chlamydia trachoma...
280
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90369
(
show subtarget assignments
)
8
cloned
CT_181
3328585
hypothetical protein [Chlamydia trachoma...
236
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90370
(
show subtarget assignments
)
8
soluble
CT_263
3328675
hypothetical protein [Chlamydia trachoma...
196
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90371
(
show subtarget assignments
)
8
cloned
CT_109
3328506
CHLPS hypothetical protein [Chlamydia tr...
262
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90267
(
show subtarget assignments
)
8
purified
TP_0326
3322602
Treponema pallidum subsp. pallidum str. ...
853
From requestor: The structural characterization of Tp0326 will be helpful in at ...
Community Requests
3EFC
11.6%
Treponema pallidum
IDP90377
(
show subtarget assignments
)
8
purified
CT_274
3328687
hypothetical protein [Chlamydia trachoma...
139
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3KD7
15.1%
Chlamydia trachomatis
IDP90376
(
show subtarget assignments
)
8
expressed
CT_266
3328678
hypothetical protein [Chlamydia trachoma...
393
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90382
(
show subtarget assignments
)
8
expressed
CT_350
3328771
hypothetical protein [Chlamydia trachoma...
566
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90379
(
show subtarget assignments
)
8
cloned
CT_330
3328749
hypothetical protein [Chlamydia trachoma...
90
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90673
(
show subtarget assignments
)
8
expressed
VC1833
15641835
quinolinate synthetase [Vibrio cholerae ...
353
Predicted Essential
Community Requests
1WZU
30.6%
Vibrio cholerae
IDP90378
(
show subtarget assignments
)
8
cloned
CT_303
3328719
hypothetical protein [Chlamydia trachoma...
171
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90675
(
show subtarget assignments
)
8
cloned
YPO3861
16123996
rffH
glucose-1-phosphate thymidylyltransferas...
293
Predicted Essential
Community Requests
1MC3
86.7%
Yersinia pestis
IDP90798
(
show subtarget assignments
)
8
purified
VC0472
15640499
S-adenosylmethionine synthetase [Vibrio ...
385
Predicted Essential
Community Requests
1FUG
87.5%
Vibrio cholerae
IDP90797
(
show subtarget assignments
)
8
in_pdb
3MUE
STM0181
16763571
panC
pantoate--beta-alanine ligase [Salmonell...
284
Predicted Essential
Community Requests
3MUE
100%
Salmonella enterica
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
Filter Columns
Filter Columns:
Target Id
Locus Tag
Priority
Stage
Ncbi Gi
Gene Name
Common Name
Length
Justification
Project
Homolog Pdb Id
Homolog Sequence Identity
Organism
Tigr Main Role
Tigr Sub Role
