Center for Structural Genomics of Infectious Diseases


CSGID ID	Priority	stage	Locus Tag	NCBI GI	Gene Name	Common Name	Sequence Length	Justification	Selection Phase	Homolog PDB ID	Homolog Sequence Identity	Target Organism	TIGR Main Role	TIGR Subrole	Request Person
IDP00684 (show subtarget assignments)	1	cloned	SACOL1926	57286273	mutY	A/G-specific adenine glycosylase	345	Drug Target Function	Phase 2: March 2008	3FSP	45.8%	Staphylococcus aureus	DNA metabolism	DNA replication, recombination, and repair

IDP00685 (show subtarget assignments)	1	soluble	SACOL2016	57284887	groEL	chaperonin GroEL	538	Drug Target Function	Phase 2: March 2008	3RTK	59.3%	Staphylococcus aureus	Protein fate	Protein folding and stabilization

IDP00686 (show subtarget assignments)	1	soluble	SACOL2029	57284899	cscA	sucrose-6-phosphate hydrolase	494	Drug Target Function	Phase 2: March 2008	1UYP	29.8%	Staphylococcus aureus	Energy metabolism	Biosynthesis and degradation of polysaccharides

IDP00687 (show subtarget assignments)	1	purified	SACOL2038	57284907		O-sialoglycoprotein endopeptidase	341	Drug Target Function	Phase 2: March 2008	2IVN	30.2%	Staphylococcus aureus	Protein fate	Degradation of proteins, peptides, and glycopeptides

IDP00688 (show subtarget assignments)	1	in_pdb 3OO2	SACOL2060	57284928	alr	alanine racemase	382	Conserved Gene / Pathway	Phase 2: March 2008	3OO2	100%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00689 (show subtarget assignments)	1	purified	SACOL2073	57284941	murF	UDP-N-acetylmuramoyl-tripeptide--D-alany...	452	Conserved Gene / Pathway	Phase 2: March 2008	2AM1	33.6%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00690 (show subtarget assignments)	1	purified	SACOL2092	57284959	murAA	UDP-N-acetylglucosamine 1-carboxyvinyltr...	421	Drug Target Function	Phase 2: March 2008	3SG1	64.1%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00691 (show subtarget assignments)	1	purified	SACOL2103	57286319		UDP-N-acetylglucosamine 2-epimerase	375	Drug Target Function	Phase 2: March 2008	1O6C	61.1%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00692 (show subtarget assignments)	1	in_pdb 3H5Q	SACOL2128	57286344	pdp	pyrimidine-nucleoside phosphorylase	433	Drug Target Function	Phase 2: March 2008	3H5Q	99.8%	Staphylococcus aureus	Purines, pyrimidines, nucleosides, and nucleotides	Other

IDP00693 (show subtarget assignments)	1	purified	SACOL2145	57286359	glmS	D-fructose-6-phosphate amidotransferase ...	601	Drug Target Function	Phase 2: March 2008	1JXA	41.4%	Staphylococcus aureus	Central intermediary metabolism	Amino sugars

IDP00694 (show subtarget assignments)	1	purified	SACOL2151	57286365	glmM	phosphoglucosamine mutase GlmM	451	Drug Target Function	Phase 2: March 2008	3PDK	67.4%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00695 (show subtarget assignments)	1	soluble	SACOL2322	57285057		peptidase, M20/M25/M40 family	373	Drug Target Function	Phase 2: March 2008	1YSJ	41.3%	Staphylococcus aureus	Protein fate	Degradation of proteins, peptides, and glycopeptides

IDP00696 (show subtarget assignments)	1	purified	SACOL2410	57285141		amino acid ABC transporter, ATP-binding ...	243	Drug Target Function	Phase 2: March 2008	2OLJ	52.3%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00697 (show subtarget assignments)	1	soluble	SACOL2563	57285245		ATP-dependent Clp protease, putative	701	Drug Target Function	Phase 2: March 2008	1QVR	43.1%	Staphylococcus aureus	Protein fate	Degradation of proteins, peptides, and glycopeptides

IDP00698 (show subtarget assignments)	1	in_pdb 3FTT 3V4E	SACOL2570	57286478		galactoside O-acetyltransferase	199	Drug Target Function	Phase 2: March 2008	3FTT	100%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP00699 (show subtarget assignments)	1	in_pdb 3ED6 3FG0	SACOL2628	57286533	betB	betaine aldehyde dehydrogenase	496	Conserved Gene / Pathway	Phase 2: March 2008	3ED6	100%	Staphylococcus aureus	Cellular processes	Adaptations to atypical conditions

IDP00700 (show subtarget assignments)	1	purified	SACOL2656	57286560	arcB2	ornithine carbamoyltransferase	336	Drug Target Function	Phase 2: March 2008	2W37	63.3%	Staphylococcus aureus	Energy metabolism	Amino acids and amines

IDP00701 (show subtarget assignments)	1	purified	SACOL0149	57285352	cap5N	capsular polysaccharide biosynthesis pro...	295	Conserved Gene / Pathway	Phase 2: March 2008	1Z45	22.4%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00702 (show subtarget assignments)	1	purified	SACOL0150	57285353	cap5O	capsular polysaccharide biosynthesis pro...	420	Drug Target Function	Phase 2: March 2008	3OJL	98.1%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00703 (show subtarget assignments)	1	purified	SACOL0250	57286711		PTS system, IIA component	263	Conserved Gene / Pathway	Phase 2: March 2008	1AX3	21.7%	Staphylococcus aureus	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP00704 (show subtarget assignments)	1	expressed	SACOL0264	57286724		ABC transporter, ATP-binding protein	219	Conserved Gene / Pathway	Phase 2: March 2008	2IT1	32%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00705 (show subtarget assignments)	1	cloned	SACOL0306	57285419		ABC transporter, ATP-binding protein	225	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	39%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00706 (show subtarget assignments)	1	soluble	SACOL0504	57285529		ABC transporter, ATP-binding protein	341	Conserved Gene / Pathway	Phase 2: March 2008	3DHW	46%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00707 (show subtarget assignments)	1	purified	SACOL0704	57285674		iron compound ABC transporter, ATP-bindi...	265	Conserved Gene / Pathway	Phase 2: March 2008	2OLJ	30.6%	Staphylococcus aureus	Transport and binding proteins	Cations and iron carrying compounds

IDP00708 (show subtarget assignments)	1	expressed	SACOL0779	57285742		ABC transporter, ATP-binding protein	625	Conserved Gene / Pathway	Phase 2: March 2008	2IW3	22.2%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00709 (show subtarget assignments)	1	soluble	SACOL0798	57285759		iron compound ABC transporter, ATP-bindi...	253	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	31.6%	Staphylococcus aureus	Transport and binding proteins	Cations and iron carrying compounds

IDP00710 (show subtarget assignments)	1	soluble	SACOL0969	57285843	spsB	signal peptidase IB	194	Drug Target Function	Phase 2: March 2008			Staphylococcus aureus	Protein fate	Protein and peptide secretion and trafficking

IDP00711 (show subtarget assignments)	1	soluble	SACOL0997	57284371		oligopeptide ABC transporter, ATP-bindin...	328	Conserved Gene / Pathway	Phase 2: March 2008	3GFO	26.8%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00712 (show subtarget assignments)	1	cloned	SACOL0998	57284372		oligopeptide ABC transporter, ATP-bindin...	326	Conserved Gene / Pathway	Phase 2: March 2008	3DHW	29.1%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00713 (show subtarget assignments)	1	purified	SACOL1108	57285894		spermidine/putrescine ABC transporter, A...	364	Conserved Gene / Pathway	Phase 2: March 2008	2D62	40.4%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00714 (show subtarget assignments)	1	cloned	SACOL1198	57285941	ftsA	cell division protein FtsA	470	Drug Target Function	Phase 2: March 2008	1E4F	18.3%	Staphylococcus aureus	Cellular processes	Cell division

IDP00715 (show subtarget assignments)	1	cloned	SACOL1414	57286065		peptide ABC transporter, ATP-binding pro...	233	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	30.5%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00716 (show subtarget assignments)	1	purified	SACOL1420	57286071		phosphate transport system protein PhoU,...	213	Conserved Gene / Pathway	Phase 2: March 2008	1T72	31%	Staphylococcus aureus	Transport and binding proteins	Anions

IDP00717 (show subtarget assignments)	1	cloned	SACOL1421	57286072		phosphate ABC transporter, ATP-binding p...	283	Conserved Gene / Pathway	Phase 2: March 2008	2OLJ	32.9%	Staphylococcus aureus	Transport and binding proteins	Anions

IDP00718 (show subtarget assignments)	1	soluble	SACOL1434	57286085		alanine racemase family protein	361	Conserved Gene / Pathway	Phase 2: March 2008	2RJG	27.1%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00719 (show subtarget assignments)	1	purified	SACOL1457	57284566		PTS system, IIA component	166	Conserved Gene / Pathway	Phase 2: March 2008	1GGR	41%	Staphylococcus aureus	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP00720 (show subtarget assignments)	1	cloned	SACOL1609	57286131	pbp3	penicillin-binding protein 3	691	Drug Target Function	Phase 2: March 2008	2WAF	32.6%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00721 (show subtarget assignments)	1	expressed	SACOL1613	57286135		ABC transporter, ATP-binding protein	261	Conserved Gene / Pathway	Phase 2: March 2008	2IT1	31.8%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00722 (show subtarget assignments)	1	soluble	SACOL1667	57284680		peptidase, U32 family	422	Drug Target Function	Phase 2: March 2008			Staphylococcus aureus	Protein fate	Degradation of proteins, peptides, and glycopeptides

IDP00723 (show subtarget assignments)	1	cloned	SACOL1668	57284681		peptidase, U32 family	307	Drug Target Function	Phase 2: March 2008			Staphylococcus aureus	Protein fate	Degradation of proteins, peptides, and glycopeptides

IDP00724 (show subtarget assignments)	1	purified	SACOL1822	57286255	arsR	arsenical resistance operon repressor	104	Conserved Gene / Pathway	Phase 2: March 2008	1R1T	31.7%	Staphylococcus aureus	Cellular processes	Detoxification

IDP00725 (show subtarget assignments)	1	cloned	SACOL1919	57284837		transcriptional regulator, Fur family	148	Conserved Gene / Pathway	Phase 2: March 2008	2FE3	63.5%	Staphylococcus aureus	Transport and binding proteins	Cations and iron carrying compounds

IDP00726 (show subtarget assignments)	1	soluble	SACOL1929	57286276		ABC transporter, ATP-binding protein, pu...	505	Conserved Gene / Pathway	Phase 2: March 2008			Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00727 (show subtarget assignments)	1	cloned	SACOL2036	57284905		ABC transporter, ATP-binding protein	642	Conserved Gene / Pathway	Phase 2: March 2008	2IW3	24.1%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00728 (show subtarget assignments)	1	cloned	SACOL2210	57284991		ABC transporter, ATP-binding protein	286	Conserved Gene / Pathway	Phase 2: March 2008	3GFO	32.2%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00729 (show subtarget assignments)	1	soluble	SACOL2356	57285089		ABC transporter, ATP-binding protein	221	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	37.1%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00730 (show subtarget assignments)	1	soluble	SACOL2453	57286449		amino acid ABC transporter, ATP-binding ...	408	Conserved Gene / Pathway	Phase 2: March 2008	2IT1	27.5%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00731 (show subtarget assignments)	1	soluble	SACOL2462	57286457		ABC transporter, ATP-binding protein	220	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	35.5%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00732 (show subtarget assignments)	1	purified	SACOL2473	57286467		peptide ABC transporter, ATP-binding pro...	271	Conserved Gene / Pathway	Phase 2: March 2008	3DHW	31.7%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00733 (show subtarget assignments)	1	selected	SACOL2419	57285149	hlgA	gamma-hemolysin, component A	309	Conserved Gene / Pathway	Phase 2: March 2008	2QK7	90.9%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP00734 (show subtarget assignments)	1	purified	SACOL0841	57284303	pgm	phosphoglyceromutase	505	Drug Target Function	Phase 2: March 2008	1EJJ	62%	Staphylococcus aureus	Energy metabolism	Glycolysis/gluconeogenesis

IDP00735 (show subtarget assignments)	1	purified	SACOL0959	57285833		NADH-dependent flavin oxidoreductase, Oy...	375	Drug Target Function	Phase 2: March 2008	3L5A	30.9%	Staphylococcus aureus	Unknown function	Enzymes of unknown specificity

IDP00736 (show subtarget assignments)	1	in_pdb 3FF1	SACOL0966	57285840	pgi	glucose-6-phosphate isomerase	443	Drug Target Function	Phase 2: March 2008	3FF1	100%	Staphylococcus aureus	Energy metabolism	Glycolysis/gluconeogenesis

IDP00737 (show subtarget assignments)	1	expressed	SACOL0993	57284367	oppD	oligopeptide ABC transporter, ATP-bindin...	360	Drug Target Function	Phase 2: March 2008	1B0U	25%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00738 (show subtarget assignments)	1	cloned	SACOL0994	57284368	oppF	oligopeptide ABC transporter, ATP-bindin...	313	Drug Target Function	Phase 2: March 2008	2YZ2	27.2%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00739 (show subtarget assignments)	1	purified	SACOL1063	57284433		acetyltransferase, GNAT family	144	Drug Target Function	Phase 2: March 2008	1Q2Y	40.3%	Staphylococcus aureus	Unknown function	Enzymes of unknown specificity

IDP00740 (show subtarget assignments)	1	cloned	SACOL1105	57285891	pdhD	dihydrolipoamide dehydrogenase	468	Drug Target Function	Phase 2: March 2008	1EBD	70.9%	Staphylococcus aureus	Energy metabolism	Pyruvate dehydrogenase

IDP00741 (show subtarget assignments)	1	purified	SACOL1253	57285992	ffh	signal recognition particle protein	455	Drug Target Function	Phase 2: March 2008	2XXA	49.5%	Staphylococcus aureus	Protein fate	Protein and peptide secretion and trafficking

IDP00742 (show subtarget assignments)	1	purified	SACOL1276	57286013	tsf	elongation factor Ts	293	Drug Target Function	Phase 2: March 2008	3AGP	44%	Staphylococcus aureus	Protein synthesis	Translation factors

IDP00743 (show subtarget assignments)	1	in_pdb 3G25 3GE1	SACOL1320	57286055	glpK	glycerol kinase	498	Drug Target Function	Phase 2: March 2008	3G25	100%	Staphylococcus aureus	Energy metabolism	Other

IDP00744 (show subtarget assignments)	1	soluble	SACOL1563	57284661	lpdA	2-oxoisovalerate dehydrogenase, E3 compo...	473	Drug Target Function	Phase 2: March 2008	3URH	37%	Staphylococcus aureus	Energy metabolism	Amino acids and amines

IDP00745 (show subtarget assignments)	1	purified	SACOL1715	57284726	hemB	delta-aminolevulinic acid dehydratase	324	Drug Target Function	Phase 2: March 2008	1B4E	47.8%	Staphylococcus aureus	Biosynthesis of cofactors, prosthetic groups, and carriers	Heme, porphyrin, and cobalamin

IDP00746 (show subtarget assignments)	1	soluble	SACOL1717	57284728	hemC	porphobilinogen deaminase	308	Drug Target Function	Phase 2: March 2008	1PDA	45.1%	Staphylococcus aureus	Biosynthesis of cofactors, prosthetic groups, and carriers	Heme, porphyrin, and cobalamin

IDP00747 (show subtarget assignments)	0	work_stopped	SACOL1768	57286203		GAF domain protein	154	Drug Target Function	Phase 2: March 2008	3KSF	98.7%	Staphylococcus aureus	Unknown function	General

IDP00748 (show subtarget assignments)	1	purified	SACOL1837	57284761	metK	S-adenosylmethionine synthetase	397	Drug Target Function	Phase 2: March 2008	1FUG	62.2%	Staphylococcus aureus	Central intermediary metabolism	One-carbon metabolism

IDP00749 (show subtarget assignments)	1	in_pdb 3PGY	SACOL2105	57286321	glyA	serine hydroxymethyltransferase	412	Drug Target Function	Phase 2: March 2008	3PGY	99.8%	Staphylococcus aureus	Amino acid biosynthesis	Serine family

IDP00750 (show subtarget assignments)	1	purified	SACOL2110	57286326	prfA	peptide chain release factor 1	358	Drug Target Function	Phase 2: March 2008	1ZBT	58.4%	Staphylococcus aureus	Protein synthesis	Translation factors

IDP00751 (show subtarget assignments)	8	purified	SACOL2117	57286333	fbaA	fructose-bisphosphate aldolase	286	Drug Target Function	Community Requests	3Q94	75.9%	Staphylococcus aureus	Energy metabolism	Glycolysis/gluconeogenesis

IDP00752 (show subtarget assignments)	1	purified	SACOL2211	57284992		ABC transporter, ATP-binding protein	269	Drug Target Function	Phase 2: March 2008	3GFO	37.5%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00753 (show subtarget assignments)	1	cloned	SACOL0052	57286607		glycosyl transferase, group 1 family pro...	503	Conserved Gene / Pathway	Phase 2: March 2008	2F9F	9.1%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00754 (show subtarget assignments)	0	work_stopped	SACOL0095	57286644	spa	immunoglobulin G binding protein A precu...	508	Conserved Gene / Pathway	Phase 2: March 2008	1BDC	11.6%	Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00755 (show subtarget assignments)	1	cloned	SACOL0099	57286648	sirA	iron compound ABC transporter, iron comp...	330	Conserved Gene / Pathway	Phase 2: March 2008	3MWF	89.1%	Staphylococcus aureus	Cell envelope	Other

IDP00756 (show subtarget assignments)	1	soluble	SACOL0115	57286664		glycosyl transferase, group 1 family pro...	388	Conserved Gene / Pathway	Phase 2: March 2008	3C48	21.8%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00757 (show subtarget assignments)	1	soluble	SACOL0135	57285338		alcohol dehydrogenase, iron-containing	869	Conserved Gene / Pathway	Phase 2: March 2008	3MY7	25.3%	Staphylococcus aureus	Energy metabolism	Fermentation

IDP00758 (show subtarget assignments)	1	soluble	SACOL0140	57285343	cap5E	capsular polysaccharide biosynthesis pro...	342	Conserved Gene / Pathway	Phase 2: March 2008	2GN4	38%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00760 (show subtarget assignments)	1	soluble	SACOL0192	57285394		maltose ABC transporter, ATP-binding pro...	365	Drug Target Function	Phase 2: March 2008	2D62	53.5%	Staphylococcus aureus	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP00762 (show subtarget assignments)	1	soluble	SACOL0209	57286673		staphylocoagulase precursor	636	Conserved Gene / Pathway	Phase 2: March 2008	2A1D	29.4%	Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00763 (show subtarget assignments)	1	expressed	SACOL0262	57286722		Ccholoylglycine hydrolase family protein...	330	Conserved Gene / Pathway	Phase 2: March 2008	2OQC	32.4%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP00764 (show subtarget assignments)	1	expressed	SACOL0447	57286820		phosphoglycerate mutase family protein	193	Drug Target Function	Phase 2: March 2008	1C7Z	31.1%	Staphylococcus aureus	Unknown function	General

IDP00768 (show subtarget assignments)	0	work_stopped	SACOL0470	57285497		superantigen-like protein	352	Virulence Associated Factor	Phase 2: March 2008	3URY	40.9%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP00769 (show subtarget assignments)	0	work_stopped	SACOL0472	57285499		superantigen-like protein	308	Virulence Associated Factor	Phase 2: March 2008	3URY	60.7%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP00770 (show subtarget assignments)	8	in_pdb 3R2I	SACOL0473	57285500		superantigen-like protein	232	Virulence Associated Factor	Community Requests	3R2I	100%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP00773 (show subtarget assignments)	1	purified	SACOL0569	57285587		ATP:guanido phosphotransferase	335	Drug Target Function	Phase 2: March 2008	3L2D	22.7%	Staphylococcus aureus	Unknown function	Enzymes of unknown specificity

IDP00774 (show subtarget assignments)	1	cloned	SACOL0597	57285613		chaperone protein HchA	292	Drug Target Function	Phase 2: March 2008	1IZY	54.1%	Staphylococcus aureus	Hypothetical proteins	Conserved

IDP00775 (show subtarget assignments)	1	soluble	SACOL0611	57285626		glycosyl transferase, group 1 family pro...	490	Conserved Gene / Pathway	Phase 2: March 2008	2JJM	14.3%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00776 (show subtarget assignments)	1	crystallized	SACOL0612	57285627		glycosyl transferase, group 1 family pro...	496	Conserved Gene / Pathway	Phase 2: March 2008	2JJM	11.3%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00777 (show subtarget assignments)	1	purified	SACOL0665	57284261		iron compound ABC transporter, iron comp...	295	Conserved Gene / Pathway	Phase 2: March 2008	3EIW	27.5%	Staphylococcus aureus	Cell envelope	Other

IDP00778 (show subtarget assignments)	1	cloned	SACOL0668	57284264		hydrolase, alpha/beta hydrolase fold fam...	266	Drug Target Function	Phase 2: March 2008	1VA4	26.1%	Staphylococcus aureus	Unknown function	Enzymes of unknown specificity

IDP00779 (show subtarget assignments)	1	soluble	SACOL0691	57285661	sirR	iron-dependent repressor	214	Conserved Gene / Pathway	Phase 2: March 2008	3HRS	37.4%	Staphylococcus aureus	Regulatory functions	DNA interactions

IDP00780 (show subtarget assignments)	1	expressed	SACOL0694	57285664		tagH protein, teichoic acid ABC transpor...	264	Conserved Gene / Pathway	Phase 2: March 2008	1VPL	23.9%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00781 (show subtarget assignments)	1	expressed	SACOL0845	57284307	est	carboxylesterase	246	Conserved Gene / Pathway	Phase 2: March 2008	1R1D	57.7%	Staphylococcus aureus	Cellular processes	Detoxification

IDP00782 (show subtarget assignments)	1	cloned	SACOL0857	57284318		staphylocoagulase precursor, putative	508	Conserved Gene / Pathway	Phase 2: March 2008	2A1D	16.9%	Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00783 (show subtarget assignments)	0	work_stopped	SACOL0885	57284344		pathogenicity island protein, integrase ...	406	Conserved Gene / Pathway	Phase 2: March 2008	3NKH	54.2%	Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00784 (show subtarget assignments)	1	soluble	SACOL0896	57284355		pathogenicity island protein	289	Conserved Gene / Pathway	Phase 2: March 2008			Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00785 (show subtarget assignments)	1	purified	SACOL0904	57285780		pathogenicity island protein	175	Conserved Gene / Pathway	Phase 2: March 2008			Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00786 (show subtarget assignments)	1	soluble	SACOL0899	57285775		pathogenicity island protein	94	Conserved Gene / Pathway	Phase 2: March 2008			Staphylococcus aureus	Cellular processes	Pathogenesis

IDP00787 (show subtarget assignments)	0	work_stopped	SACOL1016	57284388	fabI	enoyl-(acyl carrier protein) reductase	256	Drug Target Function	Phase 2: March 2008	3GNS	100%	Staphylococcus aureus	Fatty acid and phospholipid metabolism	Biosynthesis

IDP00788 (show subtarget assignments)	1	purified	SACOL1043	57284414		glycosyl transferase, group 1 family pro...	493	Conserved Gene / Pathway	Phase 2: March 2008	2JJM	16.2%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00790 (show subtarget assignments)	1	expressed	SACOL1103	57285889	pdhB	pyruvate dehydrogenase complex E1 compon...	325	Drug Target Function	Phase 2: March 2008	3DUF	75.7%	Staphylococcus aureus	Energy metabolism	Pyruvate dehydrogenase

IDP00791 (show subtarget assignments)	1	selected	SACOL1178	57284463		superantigen-like protein	238	Virulence Associated Factor	Phase 2: March 2008	1M4V	23.9%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP00684
(show subtarget assignments)

1

cloned

SACOL1926

57286273

mutY

A/G-specific adenine glycosylase

345

Drug Target Function

Phase 2: March 2008

3FSP

45.8%

Staphylococcus aureus

DNA metabolism

DNA replication, recombination, and repair

IDP00685
(show subtarget assignments)

1

soluble

SACOL2016

57284887

groEL

chaperonin GroEL

538

Drug Target Function

Phase 2: March 2008

3RTK

59.3%

Staphylococcus aureus

Protein fate

Protein folding and stabilization

IDP00686
(show subtarget assignments)

1

soluble

SACOL2029

57284899

cscA

sucrose-6-phosphate hydrolase

494

Drug Target Function

Phase 2: March 2008

1UYP

29.8%

Staphylococcus aureus

Energy metabolism

Biosynthesis and degradation of polysaccharides

IDP00687
(show subtarget assignments)

1

purified

SACOL2038

57284907

O-sialoglycoprotein endopeptidase

341

Drug Target Function

Phase 2: March 2008

2IVN

30.2%

Staphylococcus aureus

Protein fate

Degradation of proteins, peptides, and glycopeptides

IDP00688
(show subtarget assignments)

1

in_pdb
3OO2

SACOL2060

57284928

alr

alanine racemase

382

Conserved Gene / Pathway

Phase 2: March 2008

3OO2

100%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00689
(show subtarget assignments)

1

purified

SACOL2073

57284941

murF

UDP-N-acetylmuramoyl-tripeptide--D-alany...

452

Conserved Gene / Pathway

Phase 2: March 2008

2AM1

33.6%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00690
(show subtarget assignments)

1

purified

SACOL2092

57284959

murAA

UDP-N-acetylglucosamine 1-carboxyvinyltr...

421

Drug Target Function

Phase 2: March 2008

3SG1

64.1%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00691
(show subtarget assignments)

1

purified

SACOL2103

57286319

UDP-N-acetylglucosamine 2-epimerase

375

Drug Target Function

Phase 2: March 2008

1O6C

61.1%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00692
(show subtarget assignments)

1

in_pdb
3H5Q

SACOL2128

57286344

pdp

pyrimidine-nucleoside phosphorylase

433

Drug Target Function

Phase 2: March 2008

3H5Q

99.8%

Staphylococcus aureus

Purines, pyrimidines, nucleosides, and nucleotides

Other

IDP00693
(show subtarget assignments)

1

purified

SACOL2145

57286359

glmS

D-fructose-6-phosphate amidotransferase ...

601

Drug Target Function

Phase 2: March 2008

1JXA

41.4%

Staphylococcus aureus

Central intermediary metabolism

Amino sugars

IDP00694
(show subtarget assignments)

1

purified

SACOL2151

57286365

glmM

phosphoglucosamine mutase GlmM

451

Drug Target Function

Phase 2: March 2008

3PDK

67.4%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00695
(show subtarget assignments)

1

soluble

SACOL2322

57285057

peptidase, M20/M25/M40 family

373

Drug Target Function

Phase 2: March 2008

1YSJ

41.3%

Staphylococcus aureus

Protein fate

Degradation of proteins, peptides, and glycopeptides

IDP00696
(show subtarget assignments)

1

purified

SACOL2410

57285141

amino acid ABC transporter, ATP-binding ...

243

Drug Target Function

Phase 2: March 2008

2OLJ

52.3%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00697
(show subtarget assignments)

1

soluble

SACOL2563

57285245

ATP-dependent Clp protease, putative

701

Drug Target Function

Phase 2: March 2008

1QVR

43.1%

Staphylococcus aureus

Protein fate

Degradation of proteins, peptides, and glycopeptides

IDP00698
(show subtarget assignments)

1

in_pdb
3FTT
3V4E

SACOL2570

57286478

galactoside O-acetyltransferase

199

Drug Target Function

Phase 2: March 2008

3FTT

100%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP00699
(show subtarget assignments)

1

in_pdb
3ED6
3FG0

SACOL2628

57286533

betB

betaine aldehyde dehydrogenase

496

Conserved Gene / Pathway

Phase 2: March 2008

3ED6

100%

Staphylococcus aureus

Cellular processes

Adaptations to atypical conditions

IDP00700
(show subtarget assignments)

1

purified

SACOL2656

57286560

arcB2

ornithine carbamoyltransferase

336

Drug Target Function

Phase 2: March 2008

2W37

63.3%

Staphylococcus aureus

Energy metabolism

Amino acids and amines

IDP00701
(show subtarget assignments)

1

purified

SACOL0149

57285352

cap5N

capsular polysaccharide biosynthesis pro...

295

Conserved Gene / Pathway

Phase 2: March 2008

1Z45

22.4%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00702
(show subtarget assignments)

1

purified

SACOL0150

57285353

cap5O

capsular polysaccharide biosynthesis pro...

420

Drug Target Function

Phase 2: March 2008

3OJL

98.1%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00703
(show subtarget assignments)

1

purified

SACOL0250

57286711

PTS system, IIA component

263

Conserved Gene / Pathway

Phase 2: March 2008

1AX3

21.7%

Staphylococcus aureus

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP00704
(show subtarget assignments)

1

expressed

SACOL0264

57286724

ABC transporter, ATP-binding protein

219

Conserved Gene / Pathway

Phase 2: March 2008

2IT1

32%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00705
(show subtarget assignments)

1

cloned

SACOL0306

57285419

ABC transporter, ATP-binding protein

225

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

39%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00706
(show subtarget assignments)

1

soluble

SACOL0504

57285529

ABC transporter, ATP-binding protein

341

Conserved Gene / Pathway

Phase 2: March 2008

3DHW

46%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00707
(show subtarget assignments)

1

purified

SACOL0704

57285674

iron compound ABC transporter, ATP-bindi...

265

Conserved Gene / Pathway

Phase 2: March 2008

2OLJ

30.6%

Staphylococcus aureus

Transport and binding proteins

Cations and iron carrying compounds

IDP00708
(show subtarget assignments)

1

expressed

SACOL0779

57285742

ABC transporter, ATP-binding protein

625

Conserved Gene / Pathway

Phase 2: March 2008

2IW3

22.2%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00709
(show subtarget assignments)

1

soluble

SACOL0798

57285759

iron compound ABC transporter, ATP-bindi...

253

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

31.6%

Staphylococcus aureus

Transport and binding proteins

Cations and iron carrying compounds

IDP00710
(show subtarget assignments)

1

soluble

SACOL0969

57285843

spsB

signal peptidase IB

194

Drug Target Function

Phase 2: March 2008

Staphylococcus aureus

Protein fate

Protein and peptide secretion and trafficking

IDP00711
(show subtarget assignments)

1

soluble

SACOL0997

57284371

oligopeptide ABC transporter, ATP-bindin...

328

Conserved Gene / Pathway

Phase 2: March 2008

3GFO

26.8%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00712
(show subtarget assignments)

1

cloned

SACOL0998

57284372

oligopeptide ABC transporter, ATP-bindin...

326

Conserved Gene / Pathway

Phase 2: March 2008

3DHW

29.1%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00713
(show subtarget assignments)

1

purified

SACOL1108

57285894

spermidine/putrescine ABC transporter, A...

364

Conserved Gene / Pathway

Phase 2: March 2008

2D62

40.4%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00714
(show subtarget assignments)

1

cloned

SACOL1198

57285941

ftsA

cell division protein FtsA

470

Drug Target Function

Phase 2: March 2008

1E4F

18.3%

Staphylococcus aureus

Cellular processes

Cell division

IDP00715
(show subtarget assignments)

1

cloned

SACOL1414

57286065

peptide ABC transporter, ATP-binding pro...

233

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

30.5%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00716
(show subtarget assignments)

1

purified

SACOL1420

57286071

phosphate transport system protein PhoU,...

213

Conserved Gene / Pathway

Phase 2: March 2008

1T72

31%

Staphylococcus aureus

Transport and binding proteins

Anions

IDP00717
(show subtarget assignments)

1

cloned

SACOL1421

57286072

phosphate ABC transporter, ATP-binding p...

283

Conserved Gene / Pathway

Phase 2: March 2008

2OLJ

32.9%

Staphylococcus aureus

Transport and binding proteins

Anions

IDP00718
(show subtarget assignments)

1

soluble

SACOL1434

57286085

alanine racemase family protein

361

Conserved Gene / Pathway

Phase 2: March 2008

2RJG

27.1%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00719
(show subtarget assignments)

1

purified

SACOL1457

57284566

PTS system, IIA component

166

Conserved Gene / Pathway

Phase 2: March 2008

1GGR

41%

Staphylococcus aureus

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP00720
(show subtarget assignments)

1

cloned

SACOL1609

57286131

pbp3

penicillin-binding protein 3

691

Drug Target Function

Phase 2: March 2008

2WAF

32.6%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00721
(show subtarget assignments)

1

expressed

SACOL1613

57286135

ABC transporter, ATP-binding protein

261

Conserved Gene / Pathway

Phase 2: March 2008

2IT1

31.8%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00722
(show subtarget assignments)

1

soluble

SACOL1667

57284680

peptidase, U32 family

422

Drug Target Function

Phase 2: March 2008

Staphylococcus aureus

Protein fate

Degradation of proteins, peptides, and glycopeptides

IDP00723
(show subtarget assignments)

1

cloned

SACOL1668

57284681

peptidase, U32 family

307

Drug Target Function

Phase 2: March 2008

Staphylococcus aureus

Protein fate

Degradation of proteins, peptides, and glycopeptides

IDP00724
(show subtarget assignments)

1

purified

SACOL1822

57286255

arsR

arsenical resistance operon repressor

104

Conserved Gene / Pathway

Phase 2: March 2008

1R1T

31.7%

Staphylococcus aureus

Cellular processes

Detoxification

IDP00725
(show subtarget assignments)

1

cloned

SACOL1919

57284837

transcriptional regulator, Fur family

148

Conserved Gene / Pathway

Phase 2: March 2008

2FE3

63.5%

Staphylococcus aureus

Transport and binding proteins

Cations and iron carrying compounds

IDP00726
(show subtarget assignments)

1

soluble

SACOL1929

57286276

ABC transporter, ATP-binding protein, pu...

505

Conserved Gene / Pathway

Phase 2: March 2008

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00727
(show subtarget assignments)

1

cloned

SACOL2036

57284905

ABC transporter, ATP-binding protein

642

Conserved Gene / Pathway

Phase 2: March 2008

2IW3

24.1%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00728
(show subtarget assignments)

1

cloned

SACOL2210

57284991

ABC transporter, ATP-binding protein

286

Conserved Gene / Pathway

Phase 2: March 2008

3GFO

32.2%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00729
(show subtarget assignments)

1

soluble

SACOL2356

57285089

ABC transporter, ATP-binding protein

221

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

37.1%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00730
(show subtarget assignments)

1

soluble

SACOL2453

57286449

amino acid ABC transporter, ATP-binding ...

408

Conserved Gene / Pathway

Phase 2: March 2008

2IT1

27.5%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00731
(show subtarget assignments)

1

soluble

SACOL2462

57286457

ABC transporter, ATP-binding protein

220

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

35.5%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00732
(show subtarget assignments)

1

purified

SACOL2473

57286467

peptide ABC transporter, ATP-binding pro...

271

Conserved Gene / Pathway

Phase 2: March 2008

3DHW

31.7%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00733
(show subtarget assignments)

1

selected

SACOL2419

57285149

hlgA

gamma-hemolysin, component A

309

Conserved Gene / Pathway

Phase 2: March 2008

2QK7

90.9%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP00734
(show subtarget assignments)

1

purified

SACOL0841

57284303

pgm

phosphoglyceromutase

505

Drug Target Function

Phase 2: March 2008

1EJJ

62%

Staphylococcus aureus

Energy metabolism

Glycolysis/gluconeogenesis

IDP00735
(show subtarget assignments)

1

purified

SACOL0959

57285833

NADH-dependent flavin oxidoreductase, Oy...

375

Drug Target Function

Phase 2: March 2008

3L5A

30.9%

Staphylococcus aureus

Unknown function

Enzymes of unknown specificity

IDP00736
(show subtarget assignments)

1

in_pdb
3FF1

SACOL0966

57285840

pgi

glucose-6-phosphate isomerase

443

Drug Target Function

Phase 2: March 2008

3FF1

100%

Staphylococcus aureus

Energy metabolism

Glycolysis/gluconeogenesis

IDP00737
(show subtarget assignments)

1

expressed

SACOL0993

57284367

oppD

oligopeptide ABC transporter, ATP-bindin...

360

Drug Target Function

Phase 2: March 2008

1B0U

25%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00738
(show subtarget assignments)

1

cloned

SACOL0994

57284368

oppF

oligopeptide ABC transporter, ATP-bindin...

313

Drug Target Function

Phase 2: March 2008

2YZ2

27.2%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00739
(show subtarget assignments)

1

purified

SACOL1063

57284433

acetyltransferase, GNAT family

144

Drug Target Function

Phase 2: March 2008

1Q2Y

40.3%

Staphylococcus aureus

Unknown function

Enzymes of unknown specificity

IDP00740
(show subtarget assignments)

1

cloned

SACOL1105

57285891

pdhD

dihydrolipoamide dehydrogenase

468

Drug Target Function

Phase 2: March 2008

1EBD

70.9%

Staphylococcus aureus

Energy metabolism

Pyruvate dehydrogenase

IDP00741
(show subtarget assignments)

1

purified

SACOL1253

57285992

ffh

signal recognition particle protein

455

Drug Target Function

Phase 2: March 2008

2XXA

49.5%

Staphylococcus aureus

Protein fate

Protein and peptide secretion and trafficking

IDP00742
(show subtarget assignments)

1

purified

SACOL1276

57286013

tsf

elongation factor Ts

293

Drug Target Function

Phase 2: March 2008

3AGP

44%

Staphylococcus aureus

Protein synthesis

Translation factors

IDP00743
(show subtarget assignments)

1

in_pdb
3G25
3GE1

SACOL1320

57286055

glpK

glycerol kinase

498

Drug Target Function

Phase 2: March 2008

3G25

100%

Staphylococcus aureus

Energy metabolism

Other

IDP00744
(show subtarget assignments)

1

soluble

SACOL1563

57284661

lpdA

2-oxoisovalerate dehydrogenase, E3 compo...

473

Drug Target Function

Phase 2: March 2008

3URH

37%

Staphylococcus aureus

Energy metabolism

Amino acids and amines

IDP00745
(show subtarget assignments)

1

purified

SACOL1715

57284726

hemB

delta-aminolevulinic acid dehydratase

324

Drug Target Function

Phase 2: March 2008

1B4E

47.8%

Staphylococcus aureus

Biosynthesis of cofactors, prosthetic groups, and carriers

Heme, porphyrin, and cobalamin

IDP00746
(show subtarget assignments)

1

soluble

SACOL1717

57284728

hemC

porphobilinogen deaminase

308

Drug Target Function

Phase 2: March 2008

1PDA

45.1%

Staphylococcus aureus

Biosynthesis of cofactors, prosthetic groups, and carriers

Heme, porphyrin, and cobalamin

IDP00747
(show subtarget assignments)

0

work_stopped

SACOL1768

57286203

GAF domain protein

154

Drug Target Function

Phase 2: March 2008

3KSF

98.7%

Staphylococcus aureus

Unknown function

General

IDP00748
(show subtarget assignments)

1

purified

SACOL1837

57284761

metK

S-adenosylmethionine synthetase

397

Drug Target Function

Phase 2: March 2008

1FUG

62.2%

Staphylococcus aureus

Central intermediary metabolism

One-carbon metabolism

IDP00749
(show subtarget assignments)

1

in_pdb
3PGY

SACOL2105

57286321

glyA

serine hydroxymethyltransferase

412

Drug Target Function

Phase 2: March 2008

3PGY

99.8%

Staphylococcus aureus

Amino acid biosynthesis

Serine family

IDP00750
(show subtarget assignments)

1

purified

SACOL2110

57286326

prfA

peptide chain release factor 1

358

Drug Target Function

Phase 2: March 2008

1ZBT

58.4%

Staphylococcus aureus

Protein synthesis

Translation factors

IDP00751
(show subtarget assignments)

8

purified

SACOL2117

57286333

fbaA

fructose-bisphosphate aldolase

286

Drug Target Function

Community Requests

3Q94

75.9%

Staphylococcus aureus

Energy metabolism

Glycolysis/gluconeogenesis

IDP00752
(show subtarget assignments)

1

purified

SACOL2211

57284992

ABC transporter, ATP-binding protein

269

Drug Target Function

Phase 2: March 2008

3GFO

37.5%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00753
(show subtarget assignments)

1

cloned

SACOL0052

57286607

glycosyl transferase, group 1 family pro...

503

Conserved Gene / Pathway

Phase 2: March 2008

2F9F

9.1%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00754
(show subtarget assignments)

0

work_stopped

SACOL0095

57286644

spa

immunoglobulin G binding protein A precu...

508

Conserved Gene / Pathway

Phase 2: March 2008

1BDC

11.6%

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00755
(show subtarget assignments)

1

cloned

SACOL0099

57286648

sirA

iron compound ABC transporter, iron comp...

330

Conserved Gene / Pathway

Phase 2: March 2008

3MWF

89.1%

Staphylococcus aureus

Cell envelope

Other

IDP00756
(show subtarget assignments)

1

soluble

SACOL0115

57286664

glycosyl transferase, group 1 family pro...

388

Conserved Gene / Pathway

Phase 2: March 2008

3C48

21.8%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00757
(show subtarget assignments)

1

soluble

SACOL0135

57285338

alcohol dehydrogenase, iron-containing

869

Conserved Gene / Pathway

Phase 2: March 2008

3MY7

25.3%

Staphylococcus aureus

Energy metabolism

Fermentation

IDP00758
(show subtarget assignments)

1

soluble

SACOL0140

57285343

cap5E

capsular polysaccharide biosynthesis pro...

342

Conserved Gene / Pathway

Phase 2: March 2008

2GN4

38%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00760
(show subtarget assignments)

1

soluble

SACOL0192

57285394

maltose ABC transporter, ATP-binding pro...

365

Drug Target Function

Phase 2: March 2008

2D62

53.5%

Staphylococcus aureus

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP00762
(show subtarget assignments)

1

soluble

SACOL0209

57286673

staphylocoagulase precursor

636

Conserved Gene / Pathway

Phase 2: March 2008

2A1D

29.4%

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00763
(show subtarget assignments)

1

expressed

SACOL0262

57286722

Ccholoylglycine hydrolase family protein...

330

Conserved Gene / Pathway

Phase 2: March 2008

2OQC

32.4%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP00764
(show subtarget assignments)

1

expressed

SACOL0447

57286820

phosphoglycerate mutase family protein

193

Drug Target Function

Phase 2: March 2008

1C7Z

31.1%

Staphylococcus aureus

Unknown function

General

IDP00768
(show subtarget assignments)

0

work_stopped

SACOL0470

57285497

superantigen-like protein

352

Virulence Associated Factor

Phase 2: March 2008

3URY

40.9%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP00769
(show subtarget assignments)

0

work_stopped

SACOL0472

57285499

superantigen-like protein

308

Virulence Associated Factor

Phase 2: March 2008

3URY

60.7%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP00770
(show subtarget assignments)

8

in_pdb
3R2I

SACOL0473

57285500

superantigen-like protein

232

Virulence Associated Factor

Community Requests

3R2I

100%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP00773
(show subtarget assignments)

1

purified

SACOL0569

57285587

ATP:guanido phosphotransferase

335

Drug Target Function

Phase 2: March 2008

3L2D

22.7%

Staphylococcus aureus

Unknown function

Enzymes of unknown specificity

IDP00774
(show subtarget assignments)

1

cloned

SACOL0597

57285613

chaperone protein HchA

292

Drug Target Function

Phase 2: March 2008

1IZY

54.1%

Staphylococcus aureus

Hypothetical proteins

Conserved

IDP00775
(show subtarget assignments)

1

soluble

SACOL0611

57285626

glycosyl transferase, group 1 family pro...

490

Conserved Gene / Pathway

Phase 2: March 2008

2JJM

14.3%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00776
(show subtarget assignments)

1

crystallized

SACOL0612

57285627

glycosyl transferase, group 1 family pro...

496

Conserved Gene / Pathway

Phase 2: March 2008

2JJM

11.3%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00777
(show subtarget assignments)

1

purified

SACOL0665

57284261

iron compound ABC transporter, iron comp...

295

Conserved Gene / Pathway

Phase 2: March 2008

3EIW

27.5%

Staphylococcus aureus

Cell envelope

Other

IDP00778
(show subtarget assignments)

1

cloned

SACOL0668

57284264

hydrolase, alpha/beta hydrolase fold fam...

266

Drug Target Function

Phase 2: March 2008

1VA4

26.1%

Staphylococcus aureus

Unknown function

Enzymes of unknown specificity

IDP00779
(show subtarget assignments)

1

soluble

SACOL0691

57285661

sirR

iron-dependent repressor

214

Conserved Gene / Pathway

Phase 2: March 2008

3HRS

37.4%

Staphylococcus aureus

Regulatory functions

DNA interactions

IDP00780
(show subtarget assignments)

1

expressed

SACOL0694

57285664

tagH protein, teichoic acid ABC transpor...

264

Conserved Gene / Pathway

Phase 2: March 2008

1VPL

23.9%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00781
(show subtarget assignments)

1

expressed

SACOL0845

57284307

est

carboxylesterase

246

Conserved Gene / Pathway

Phase 2: March 2008

1R1D

57.7%

Staphylococcus aureus

Cellular processes

Detoxification

IDP00782
(show subtarget assignments)

1

cloned

SACOL0857

57284318

staphylocoagulase precursor, putative

508

Conserved Gene / Pathway

Phase 2: March 2008

2A1D

16.9%

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00783
(show subtarget assignments)

0

work_stopped

SACOL0885

57284344

pathogenicity island protein, integrase ...

406

Conserved Gene / Pathway

Phase 2: March 2008

3NKH

54.2%

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00784
(show subtarget assignments)

1

soluble

SACOL0896

57284355

pathogenicity island protein

289

Conserved Gene / Pathway

Phase 2: March 2008

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00785
(show subtarget assignments)

1

purified

SACOL0904

57285780

pathogenicity island protein

175

Conserved Gene / Pathway

Phase 2: March 2008

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00786
(show subtarget assignments)

1

soluble

SACOL0899

57285775

pathogenicity island protein

94

Conserved Gene / Pathway

Phase 2: March 2008

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP00787
(show subtarget assignments)

0

work_stopped

SACOL1016

57284388

fabI

enoyl-(acyl carrier protein) reductase

256

Drug Target Function

Phase 2: March 2008

3GNS

100%

Staphylococcus aureus

Fatty acid and phospholipid metabolism

Biosynthesis

IDP00788
(show subtarget assignments)

1

purified

SACOL1043

57284414

glycosyl transferase, group 1 family pro...

493

Conserved Gene / Pathway

Phase 2: March 2008

2JJM

16.2%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00790
(show subtarget assignments)

1

expressed

SACOL1103

57285889

pdhB

pyruvate dehydrogenase complex E1 compon...

325

Drug Target Function

Phase 2: March 2008

3DUF

75.7%

Staphylococcus aureus

Energy metabolism

Pyruvate dehydrogenase

IDP00791
(show subtarget assignments)

1

selected

SACOL1178

57284463

superantigen-like protein

238

Virulence Associated Factor

Phase 2: March 2008

1M4V

23.9%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

Targets