Center for Structural Genomics of Infectious Diseases

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Page 7 of 60, showing 100 records out of 5960 total, starting on record 601

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CSGID ID	Priority	stage	Locus Tag	NCBI GI	Gene Name	Common Name	Sequence Length	Justification	Selection Phase	Homolog PDB ID	Homolog Sequence Identity	Target Organism	TIGR Main Role	TIGR Subrole	Request Person
IDP00339 (show subtarget assignments)	1	expressed	FTT0711	56707830	ispD	2-C-methyl-D-erythritol 4-phosphate cyti...	229	Drug Target Function	Phase 2: March 2008	1H3M	37.1%	Francisella tularensis

IDP90549 (show subtarget assignments)	8	in_pdb 3L92 3L93	YPO0053	16120406	coaD	phosphopantetheine adenylyltransferase [...	159	Predicted Essential	Community Requests	3L92	100%	Yersinia pestis

IDP90552 (show subtarget assignments)	8	soluble	YPO0058	16120411	rfaD	ADP-L-glycero-D-mannoheptose-6-epimerase...	310	Predicted Essential	Community Requests	1EQ2	82.3%	Yersinia pestis

IDP90551 (show subtarget assignments)	8	diffraction	VC0875	15640891		prolyl-tRNA synthetase [Vibrio cholerae ...	571	Predicted Essential	Community Requests	2J3L	45.5%	Vibrio cholerae

IDP00341 (show subtarget assignments)	1	cloned	FTT1305c	56708363	murA	UDP-N-acetylglucosamine 1-carboxyvinyltr...	444	Drug Target Function	Phase 2: March 2008	3SG1	32.7%	Francisella tularensis

IDP90553 (show subtarget assignments)	8	soluble	VC2458	15642454		pyridoxal phosphate biosynthetic protein...	243	Predicted Essential	Community Requests	1M5W	70.8%	Vibrio cholerae

IDP90562 (show subtarget assignments)	8	purified	Cj0434	15791801	pgm	phosphoglyceromutase [Campylobacter jeju...	492	Predicted Essential	Community Requests	1EJJ	44%	Campylobacter jejuni

IDP90592 (show subtarget assignments)	8	purified	VC2389	15642386	carB	carbamoyl phosphate synthase large subun...	1076	Predicted Essential	Community Requests	1BXR	85.6%	Vibrio cholerae

IDP90788 (show subtarget assignments)	8	purified	Cj0512	15791874	purC	phosphoribosylaminoimidazole-succinocarb...	236	Predicted Essential	Community Requests	3NUA	50.8%	Campylobacter jejuni

IDP90789 (show subtarget assignments)	8	crystallized	YPO3389	16123538	hemL	glutamate-1-semialdehyde aminotransferas...	426	Predicted Essential	Community Requests	3K28	55.9%	Yersinia pestis

IDP90559 (show subtarget assignments)	8	cloned	VC0240	15640270	rfaD	ADP-L-glycero-D-mannoheptose-6-epimerase...	314	Predicted Essential	Community Requests	1EQ2	73.9%	Vibrio cholerae

IDP90381 (show subtarget assignments)	8	cloned	CT_309	3328725		hypothetical protein [Chlamydia trachoma...	266	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90560 (show subtarget assignments)	8	purified	YPO2014	16122257	ipk	4-diphosphocytidyl-2-C-methyl-D-erythrit...	299	Predicted Essential	Community Requests	1OJ4	70.9%	Yersinia pestis

IDP90792 (show subtarget assignments)	8	in_pdb 3O8Q 3SEF 3PGJ	VC0056	15640088	aroE	shikimate 5-dehydrogenase [Vibrio choler...	278	Predicted Essential	Community Requests	3O8Q	100%	Vibrio cholerae

IDP90570 (show subtarget assignments)	8	crystallized	Cj0953c	15792282	purH	bifunctional phosphoribosylaminoimidazol...	510	Predicted Essential	Community Requests	3ZZM	39.2%	Campylobacter jejuni

IDP90571 (show subtarget assignments)	8	expressed	YPO0416	16120749		putative lipopolysaccharide core biosynt...	346	Predicted Essential	Community Requests	3TOV	24.9%	Yersinia pestis

IDP90563 (show subtarget assignments)	8	soluble	VC0061	15640093		thiamine biosynthesis protein ThiC [Vibr...	645	Predicted Essential	Community Requests	3EPM	65%	Vibrio cholerae

IDP90564 (show subtarget assignments)	8	in_pdb 3M34 3M6L 3M7I 3L84	Cj1645	15792950	tkt	transketolase [Campylobacter jejuni subs...	632	Predicted Essential	Community Requests	3L84	100%	Campylobacter jejuni

IDP90566 (show subtarget assignments)	8	in_pdb 3QBO	YPO1389	16121669	serC	phosphoserine aminotransferase [Yersinia...	361	Predicted Essential	Community Requests	3QBO	96.7%	Yersinia pestis

IDP90569 (show subtarget assignments)	8	soluble	VC0369	15640396	rplI	50S ribosomal protein L9 [Vibrio cholera...	149	Predicted Essential	Community Requests	1P85	76.5%	Vibrio cholerae

IDP90568 (show subtarget assignments)	8	soluble	Cj0536	15791897	oorA	2-oxoglutarate-acceptor oxidoreductase s...	374	Predicted Essential	Community Requests	1YD7	43%	Campylobacter jejuni

IDP90567 (show subtarget assignments)	8	in_pdb 3R2E	YPO0648	16120973	folB	bifunctional dihydroneopterin aldolase/d...	119	Predicted Essential	Community Requests	3R2E	100%	Yersinia pestis

IDP90572 (show subtarget assignments)	8	in_pdb 3R8X	YPO0241	16120579	fmt	methionyl-tRNA formyltransferase [Yersin...	315	Predicted Essential	Community Requests	3R8X	100%	Yersinia pestis

IDP90377 (show subtarget assignments)	8	purified	CT_274	3328687		hypothetical protein [Chlamydia trachoma...	139	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests	3KD7	15.1%	Chlamydia trachomatis

IDP90573 (show subtarget assignments)	8	cloned	Cj0479	15791843	rpoC	DNA-directed RNA polymerase beta' chain ...	1517	Predicted Essential	Community Requests	3IYD	46.1%	Campylobacter jejuni

IDP90574 (show subtarget assignments)	8	in_pdb 3NX3	Cj0227	15791599	argD	acetylornithine aminotransferase [Campyl...	395	Predicted Essential	Community Requests	3NX3	100%	Campylobacter jejuni

IDP90578 (show subtarget assignments)	8	expressed	YPO3401	16123550	panB	3-methyl-2-oxobutanoate hydroxymethyltra...	266	Predicted Essential	Community Requests	1M3U	75.9%	Yersinia pestis

IDP90577 (show subtarget assignments)	8	soluble	VC1848	15641850	cysS	cysteinyl-tRNA synthetase [Vibrio choler...	459	Predicted Essential	Community Requests	1LI5	75.1%	Vibrio cholerae

IDP90580 (show subtarget assignments)	8	cloned	Cj1091c	15792416	leuS	leucyl-tRNA synthetase [Campylobacter je...	809	Predicted Essential	Community Requests	1H3N	42.1%	Campylobacter jejuni

IDP90579 (show subtarget assignments)	8	soluble	VC0528	15640550	ispD	2-C-methyl-D-erythritol 4-phosphate cyti...	232	We have identified the methylerythritol phosphate (MEP) pathway enzymes, novel d...	Community Requests	1H3M	53.9%	Vibrio cholerae

IDP90376 (show subtarget assignments)	8	expressed	CT_266	3328678		hypothetical protein [Chlamydia trachoma...	393	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90584 (show subtarget assignments)	8	purified	VC0095	15640127		chorismate--pyruvate lyase [Vibrio chole...	183	Predicted Essential	Community Requests	1FW9	28.4%	Vibrio cholerae

IDP90583 (show subtarget assignments)	8	soluble	Cj1243	15792567	hemE	uroporphyrinogen decarboxylase [Campylob...	340	Predicted Essential	Community Requests	3CYV	45.2%	Campylobacter jejuni

IDP90804 (show subtarget assignments)	8	soluble	VC0397	15640424		single-strand DNA-binding protein [Vibri...	177	Predicted Essential	Community Requests	1EQQ	75.1%	Vibrio cholerae

IDP90166 (show subtarget assignments)	8	soluble	CD1837	126699446	aroE	shikimate dehydrogenase [Clostridium dif...	269	Potential drug target. Shikimate pathway enzyme	Community Requests	3FBT	42%	Clostridium difficile

IDP90585 (show subtarget assignments)	8	purified	Cj0949c	15792278		peptidyl-arginine deiminase family prote...	325	Predicted Essential	Community Requests	3HVM	45.8%	Campylobacter jejuni

IDP90586 (show subtarget assignments)	8	cloned	YPO2188	16122418	cls	cardiolipin synthetase [Yersinia pestis ...	486	Predicted Essential	Community Requests			Yersinia pestis

IDP90587 (show subtarget assignments)	8	in_pdb 3LXM	YPO3588	16123730	pyrB	aspartate carbamoyltransferase catalytic...	311	Predicted Essential	Community Requests	3LXM	100%	Yersinia pestis

IDP90375 (show subtarget assignments)	8	purified	CT_296	3328711		hypothetical protein [Chlamydia trachoma...	155	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests	3QH6	98.1%	Chlamydia trachomatis

IDP90387 (show subtarget assignments)	8	expressed	CT_372	3328796		hypothetical protein [Chlamydia trachoma...	442	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90397 (show subtarget assignments)	8	purified	CT_583	3329026	gp6D	CHLTR Plasmid Paralog [Chlamydia trachom...	263	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90398 (show subtarget assignments)	8	soluble	CT_577	3329019		hypothetical protein [Chlamydia trachoma...	119	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90386 (show subtarget assignments)	8	expressed	CT_355	3328776		hypothetical protein [Chlamydia trachoma...	353	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90595 (show subtarget assignments)	8	expressed	YPO2298	16122522	phoA	alkaline phosphatase [Yersinia pestis CO...	481	Predicted Essential	Community Requests	1B8J	70.7%	Yersinia pestis

IDP90385 (show subtarget assignments)	8	cloned	CT_392	3328818	yprS	hypothetical protein [Chlamydia trachoma...	377	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90379 (show subtarget assignments)	8	cloned	CT_330	3328749		hypothetical protein [Chlamydia trachoma...	90	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90390 (show subtarget assignments)	8	cloned	CT_377	3328802	ltuA	hypothetical protein [Chlamydia trachoma...	46	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90374 (show subtarget assignments)	8	expressed	CT_338	3328758		hypothetical protein [Chlamydia trachoma...	153	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90378 (show subtarget assignments)	8	cloned	CT_303	3328719		hypothetical protein [Chlamydia trachoma...	171	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90392 (show subtarget assignments)	8	purified	CT_584	3329027		hypothetical protein [Chlamydia trachoma...	183	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests	3Q9D	83.1%	Chlamydia trachomatis

IDP90122 (show subtarget assignments)	8	expressed	MPXV_ZAI1979_005_032	68449106		serine protease inhibitor-likeprotein SP...	375	similar to VACV-COP-K2L, MPXV-ZAI96-C2L	Community Requests	3LW2	29.2%	Monkeypox virus

IDP90373 (show subtarget assignments)	8	expressed	CT_191	3328596		hypothetical protein [Chlamydia trachoma...	116	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90083 (show subtarget assignments)	8	cloned	ZP_01795671	145640077		hypothetical protein CGSHiII_00664 [Haem...	219	The protein we would like structure analyzed is from Haemophilus influenzae. Pri...	Community Requests	2XM6	35.6%	Haemophilus influenzae

IDP90165 (show subtarget assignments)	8	purified	CD1834	123174271		3-phosphoshikimate 1-carboxyvinyltransfe...	437	Potential drug target. Shikimate pathway enzyme	Community Requests	3NVS	32.5%	Clostridium difficile

IDP90383 (show subtarget assignments)	8	cloned	CT_412	3328840	pmpA	Putative outer membrane protein A [Chlam...	975	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90380 (show subtarget assignments)	8	expressed	CT_311	3328727		hypothetical protein [Chlamydia trachoma...	236	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90393 (show subtarget assignments)	8	cloned	CT_567	3329008		hypothetical protein [Chlamydia trachoma...	174	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90606 (show subtarget assignments)	8	purified	VC0563	15640585	trmD	tRNA (guanine-N(1)-)-methyltransferase [...	247	Predicted Essential	Community Requests	1P9P	78.1%	Vibrio cholerae

IDP90372 (show subtarget assignments)	8	expressed	CT_253	3328664		hypothetical protein [Chlamydia trachoma...	215	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90082 (show subtarget assignments)	8	purified	P03493.2	85681917		RecName: Full=Matrix protein 2; AltName:...	109	Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...	Community Requests	2KJ1	64.2%	Influenza B

IDP90371 (show subtarget assignments)	8	cloned	CT_109	3328506		CHLPS hypothetical protein [Chlamydia tr...	262	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90395 (show subtarget assignments)	8	cloned	CT_573	3329014		hypothetical protein [Chlamydia trachoma...	409	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Chlamydia trachomatis

IDP90001 (show subtarget assignments)	8	cloned	FTT0094c	56603762	qseC	sensor histidine kinase	475	Drug Target (Community Request)	Community Requests	3A0R	15.8%	Francisella tularensis

IDP90081 (show subtarget assignments)	8	cloned	ABD79034.1	89892477	M2	matrix protein 2 [Influenza A virus (A/U...	96	Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...	Community Requests	2L0J	42.7%	Influenza A

IDP90607 (show subtarget assignments)	8	purified	VC2015	15642017		DNA polymerase III subunit delta' [Vibri...	324	Predicted Essential	Community Requests	1A5T	33%	Vibrio cholerae

IDP90000 (show subtarget assignments)	8	cloned	FTT1352	56708408		hypothetical protein FTT1352	383	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests			Francisella tularensis

IDP90007 (show subtarget assignments)	8	cloned	Z4378	12517596	qseC	quorum sensing Escherichia coli regulato...	449	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests	3JZ3	47%	Escherichia coli

IDP90610 (show subtarget assignments)	8	soluble	YPO4071	16124184	glyS	glycyl-tRNA synthetase subunit beta [Yer...	689	Predicted Essential	Community Requests			Yersinia pestis

IDP90005 (show subtarget assignments)	8	soluble	Z4377	12517595	qseB	quorum sensing Escherichia coli regulato...	219	These targets are similar to actual drug targets and will be used mostly for coc...	Community Requests	3Q9S	41.1%	Escherichia coli

IDP90003 (show subtarget assignments)	8	purified	FTT1103	56708183		conserved hypothetical lipoprotein	365	(Community Request)	Community Requests	3GYK	12.3%	Francisella tularensis

IDP90090 (show subtarget assignments)	8	expressed	ZZZ_0006				310	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90085 (show subtarget assignments)	8	purified	ZZZ_0001				158	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90103 (show subtarget assignments)	8	cloned	MPXV_ZAI1979_005_003	68449080		ankyrin-like protein [Monkeypox virus]	587	similar to VACV-COP-B25R/C19L, MPXV-ZAI96-J3L/J1R	Community Requests			Monkeypox virus

IDP90084 (show subtarget assignments)	8	soluble	ZP_01795673	145640079		hypothetical protein CGSHiII_00674 [Haem...	148	The protein we would like structure analyzed is from Haemophilus influenzae. Pri...	Community Requests	2XM6	28.4%	Haemophilus influenzae

IDP90086 (show subtarget assignments)	8	expressed	ZZZ_0002				492	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90089 (show subtarget assignments)	8	expressed	ZZZ_0005				600	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90088 (show subtarget assignments)	8	soluble	ZZZ_0004				140	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90087 (show subtarget assignments)	8	cloned	ZZZ_0003				168	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90092 (show subtarget assignments)	8	purified	ZZZ_0008				155	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90091 (show subtarget assignments)	8	expressed	ZZZ_0007				660	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests	2P5Z	15.6%	Escherichia coli

IDP90094 (show subtarget assignments)	8	cloned	ZZZ_0010				358	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90093 (show subtarget assignments)	8	expressed	ZZZ_0009				99	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90097 (show subtarget assignments)	8	cloned	ZZZ_0013				104	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90096 (show subtarget assignments)	8	expressed	ZZZ_0012				476	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90098 (show subtarget assignments)	8	purified	ZZZ_0014				196	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90099 (show subtarget assignments)	8	cloned	ZZZ_0015				1137	This protein is a component of a type VI secretion system of enteroaggregative E...	Community Requests			Escherichia coli

IDP90104 (show subtarget assignments)	8	expressed	MPXV_ZAI1979_005_004	68449081		ankyrin-like protein [Monkeypox virus]	437	similar to CPXV-GRI-C1L, MPXV-ZAI96-D1L/N4R	Community Requests	2Y1L	9.6%	Monkeypox virus

IDP90108 (show subtarget assignments)	8	soluble	MPXV_ZAI1979_005_013	68449087		bifunctional zinc finger-like protein/E3...	242	similar to VARV BEN68-zinc finger-like protein	Community Requests	2ECW	8.3%	Monkeypox virus

IDP90105 (show subtarget assignments)	8	expressed	MPXV_ZAI1979_005_008	68449082		unknown [Monkeypox virus]	56	similar to part of CPXV-GRI-C3L	Community Requests			Monkeypox virus

IDP90106 (show subtarget assignments)	8	cloned	MPXV_ZAI1979_005_011	68449085		secreted epidermal growth factor-like pr...	142	similar to VACV-COP-C11R, MPXV-ZAI96-D3R	Community Requests	1K36	16.2%	Monkeypox virus

IDP00175 (show subtarget assignments)	1	soluble	YPO1471	16121746	-	putative ATPase subunit of ATP-dependent...	880	Virulence	Phase 1: October 2007	1QVR	36.9%	Yersinia pestis

IDP90109 (show subtarget assignments)	8	cloned	MPXV_ZAI1979_005_014	68449088		interleukin-18-binding protein [Monkeypo...	126	similar to VACWR-C12L,VARV-BSH75_banu-D7L, MPXV-ZAI96-D6L	Community Requests	3F62	79.4%	Monkeypox virus

IDP90110 (show subtarget assignments)	8	soluble	MPXV_ZAI1979_005_015	68449089		ankyrin-like protein [Monkeypox virus]	660	similar to CPXV-GRI-C9L,CPXV-BR-V024, MPXV-ZAI96-D7L	Community Requests	1N0Q	4.4%	Monkeypox virus

IDP90111 (show subtarget assignments)	8	soluble	MPXV_ZAI1979_005_017	68449091		ankyrin-like protein [Monkeypox virus]	630	similar to VACV-COP-C9L, MPXV-ZAI96-D9L	Community Requests	3NOC	5.1%	Monkeypox virus

IDP90116 (show subtarget assignments)	8	cloned	MPXV_ZAI1979_005_025	68449099		kelch-like protein [Monkeypox virus]	107	similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L	Community Requests	3HVE	21.5%	Monkeypox virus

IDP90119 (show subtarget assignments)	8	soluble	MPXV_ZAI1979_005_029	68449103		ankyrin-like protein [Monkeypox virus]	442	similar to VACV-COP-M1L, MPXV-ZAI96-O1L	Community Requests	1N11	16.3%	Monkeypox virus

IDP90113 (show subtarget assignments)	8	expressed	MPXV_ZAI1979_005_021	68449095		unknown [Monkeypox virus]	315	similar to VACV-COP-C4L, MPXV-ZAI96-D13L	Community Requests			Monkeypox virus

IDP90114 (show subtarget assignments)	8	soluble	MPXV_ZAI1979_005_023	68449097		kelch-like protein [Monkeypox virus]	105	similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L	Community Requests			Monkeypox virus

IDP90898 (show subtarget assignments)	8	soluble	STM0416	16763796	ribD	bifunctional diaminohydroxyphosphoribosy...	367	Predicted Essential	Community Requests	2G6V	89.4%	Salmonella enterica

IDP90897 (show subtarget assignments)	8	expressed	VC0956	15640972	leuS	leucyl-tRNA synthetase [Vibrio cholerae ...	894	Predicted Essential	Community Requests	1H3N	46.3%	Vibrio cholerae

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