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Targets
Filter Targets:
Selection Phase:
No Filter
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM 10
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
Clostridium difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Remove Filters
Download data as tab-separated value (TSV) file
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Page 9 of 60, showing 100 records out of 5960 total, starting on record 801
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CSGID ID
Priority
stage
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90191
(
show subtarget assignments
)
8
expressed
AAM13632.1
20153171
CPXV193 CDS
CPXV193 protein
563
kelch-like protein
Community Requests
3II7
13%
Cowpox virus
conserved hypothetical proteins
0
IDP90190
(
show subtarget assignments
)
8
cloned
AAM13631.1
20153170
CrmC
CrmC or CPXV191 protein
186
soluble vTNF receptor CrmC
Community Requests
3ALQ
30.6%
Cowpox virus
host defense modulator
0
IDP00810
(
show subtarget assignments
)
1
cloned
SACOL1870
57284791
hypothetical protein SACOL1870
188
Conserved Gene / Pathway
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP90192
(
show subtarget assignments
)
8
cloned
AAM13635.1
20153174
CPXV196 CDS
CPXV196 protein
299
serine-threonine kinase
Community Requests
2KTY
40.7%
Cowpox virus
Unknown function
0
IDP90204
(
show subtarget assignments
)
8
cloned
AAM13452.1
20152991
CPXV006 CDS
CPXV006 protein
619
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90188
(
show subtarget assignments
)
8
cloned
AAM13496.1
20153035
CPXV050 CDS
CPXV050 protein
480
kelch-like protein
Community Requests
3II7
12.3%
Cowpox virus
conserved hypothetical proteins
0
IDP90184
(
show subtarget assignments
)
8
expressed
AAM13486.1
20153025
CPXV039 CDS
CPXV039 protein
473
ankyrin repeat protein
Community Requests
1N11
14.4%
Cowpox virus
conserved hypothetical proteins
0
IDP90185
(
show subtarget assignments
)
0
work_stopped
AAM13488.1
20153027
CPXV041 CDS
CPXV041 protein
284
K1L like Host range protein
Community Requests
3KEA
95.1%
Cowpox virus
host defense modulator
0
IDP90186
(
show subtarget assignments
)
8
cloned
AAM13489.1
20153028
SPI3
SPI3 or CPXV042 protein
373
serine protease inhibitor 3
Community Requests
3LW2
28.7%
Cowpox virus
host defense modulator
0
IDP90189
(
show subtarget assignments
)
8
cloned
AAM13616.1
20153155
CPXV175 CDS
CPXV175 protein
277
CD47-like putative membrane proteinÂ
Community Requests
2JJS
13%
Cowpox virus
host defense modulator
0
IDP90187
(
show subtarget assignments
)
8
cloned
AAM13490.1
20153029
CPXV043 CDS
CPXV043 protein
88
IFN resistance, K3L like
Community Requests
1LUZ
90.9%
Cowpox virus
host defense modulator
0
IDP90179
(
show subtarget assignments
)
8
cloned
AAM13473.1
20153012
CPXV025 CDS
CPXV026 protein
63
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90180
(
show subtarget assignments
)
8
cloned
AAM13474.1
20153013
CPXV027 CDS
CPXV027 protein
632
ankyrin-like protein
Community Requests
3NOC
5.4%
Cowpox virus
conserved hypothetical proteins
0
IDP90177
(
show subtarget assignments
)
8
expressed
AAM13471.1
20153010
CPXV024 CDS
CPXV024 protein
126
Orthopoxvirus interleukin 18 binding protein; plays a key role in the activation...
Community Requests
3F62
80.2%
Cowpox virus
host defense modulator
0
IDP90178
(
show subtarget assignments
)
8
purified
AAM13472.1
20153011
VHR1
VHR1 or CPXV025 protein
668
ankyrin-like protein, CP77
Community Requests
1N11
10%
Cowpox virus
host range protein
0
IDP90181
(
show subtarget assignments
)
8
cloned
AAM13478.1
20153017
CPXV031 CDS
CPXV031 protein
69
kelch-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90176
(
show subtarget assignments
)
8
expressed
AAM13470.1
20153009
CPXV023 CDS
CPXV023 protein
242
zinc-finger-like protein
Community Requests
2ECW
8.3%
Cowpox virus
host defense modulator
0
IDP90182
(
show subtarget assignments
)
8
soluble
AAM13479.1
20153018
CPXV032
CPXV032 protein
125
kelch-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP00616
(
show subtarget assignments
)
1
cloned
SACOL1586
57286108
hypothetical protein SACOL1586
94
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP90175
(
show subtarget assignments
)
8
expressed
AAM13468.1
20153007
VGF
CPXV021 protein or CPXV VGF protein
139
similar to viral growth factor C11R vaccinia virus
Community Requests
1K36
15.8%
Cowpox virus
host range protein
0
IDP00600
(
show subtarget assignments
)
1
cloned
SACOL0532
57285557
hypothetical protein SACOL0532
51
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP90183
(
show subtarget assignments
)
8
cloned
AAM13482.1
20153021
CPXV035 CDS
CPXV035 protein
512
kelch-like protein
Community Requests
2XN4
12.7%
Cowpox virus
conserved hypothetical proteins
0
IDP90205
(
show subtarget assignments
)
8
expressed
AAM13465.1
20153004
CPXV018 CDS
CPXV018 protein, VO18
171
similar to MPV-Z-N3R
Community Requests
Cowpox virus
host defense modulator
0
IDP00225
(
show subtarget assignments
)
1
cloned
YPO3069
16123246
-
putative exported protein
486
Virulence
Phase 1: October 2007
3C37
15%
Yersinia pestis
Purines, pyrimidines, nucleosides, and nucleotides
2'-Deoxyribonucleotide metabolism
IDP02455
(
show subtarget assignments
)
1
expressed
GBAA3813
47529098
prophage LambdaBa01, thymidylate synthas...
252
Conserved; Drug target functions
Phase 3: June 2008
3AH5
24.6%
Bacillus anthracis
Purines, pyrimidines, nucleosides, and nucleotides
2'-Deoxyribonucleotide metabolism
IDP04496
(
show subtarget assignments
)
1
expressed
VC0675
15640694
thyA
thymidylate synthase [Vibrio cholerae O1...
283
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3V8H
35.9%
Vibrio cholerae
Purines, pyrimidines, nucleosides, and nucleotides
2'-Deoxyribonucleotide metabolism
IDP02391
(
show subtarget assignments
)
1
cloned
FTT0534c
56707667
nrdA
ribonucleotide-diphosphate reductase sub...
590
Drug Target
Phase 3: June 2008
2WGH
31.2%
Francisella tularensis
Purines, pyrimidines, nucleosides, and nucleotides
2'-Deoxyribonucleotide metabolism
IDP02400
(
show subtarget assignments
)
1
purified
YPO3454
16123600
nrdD
anaerobic ribonucleoside triphosphate re...
712
Conserved; CD; Drug target functions
Phase 3: June 2008
1H78
48.2%
Yersinia pestis
Purines, pyrimidines, nucleosides, and nucleotides
2'-Deoxyribonucleotide metabolism
IDP02619
(
show subtarget assignments
)
1
cloned
GBAA1372
47526645
nrdF
ribonucleotide-diphosphate reductase sub...
322
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
1KGN
44.6%
Bacillus anthracis
Purines, pyrimidines, nucleosides, and nucleotides
2'-Deoxyribonucleotide metabolism
IDP01318
(
show subtarget assignments
)
1
in_pdb
3IQ1
VC0139
15640170
DPS family protein
156
Conserved Gene / Pathway
Phase 2: March 2008
3IQ1
100%
Vibrio cholerae
Cellular processes
Adaptations to atypical conditions
IDP00576
(
show subtarget assignments
)
1
cloned
YPO1398
16121678
cspB
cold shock-like protein
69
Virulence Associated Factor
Phase 2: March 2008
3I2Z
50.7%
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP00557
(
show subtarget assignments
)
1
purified
YPO3382
16123531
gsrA
serine endoprotease
481
Virulence Associated Factor
Phase 2: March 2008
2ZLE
71.9%
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP01061
(
show subtarget assignments
)
1
purified
STM3591
16766877
uspA
universal stress protein A
144
Conserved Gene / Pathway
Phase 2: March 2008
1JMV
66.7%
Salmonella enterica
Cellular processes
Adaptations to atypical conditions
IDP00524
(
show subtarget assignments
)
1
purified
YPO0490
16120820
apaH
diadenosine tetraphosphatase
289
Conserved Gene / Pathway
Phase 2: March 2008
2DFJ
73.7%
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP04269
(
show subtarget assignments
)
1
cloned
CPF_2193
110798612
relA
GTP pyrophosphokinase [Clostridium perfr...
726
conserved gene; putative drug target function;
Phase 4: April 2009
1VJ7
28.1%
Clostridium perfringens
Cellular processes
Adaptations to atypical conditions
IDP01613
(
show subtarget assignments
)
1
purified
STM1927
16765269
yecG
universal stress protein UspC [Salmonell...
142
Conserved; Drug target functions
Phase 3: June 2008
1JMV
35.2%
Salmonella enterica
Cellular processes
Adaptations to atypical conditions
IDP04697
(
show subtarget assignments
)
1
soluble
YPCD1.29c
16082717
yopB
secreted effector protein [Yersinia pest...
401
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP04018
(
show subtarget assignments
)
1
cloned
CPF_1860
110799668
msrB
methionine sulfoxide reductase B [Clostr...
147
conserved gene; putative drug target function;
Phase 4: April 2009
1XM0
64.6%
Clostridium perfringens
Cellular processes
Adaptations to atypical conditions
IDP04552
(
show subtarget assignments
)
1
cloned
CPF_2913
110799629
msrA
methionine sulfoxide reductase A [Clostr...
157
conserved gene; putative drug target function;
Phase 4: April 2009
3BQE
52.2%
Clostridium perfringens
Cellular processes
Adaptations to atypical conditions
IDP01516
(
show subtarget assignments
)
1
crystallized
VC0576
15640598
sspA
stringent starvation protein A
211
Conserved Gene / Pathway
Phase 2: March 2008
1YY7
73.9%
Vibrio cholerae
Cellular processes
Adaptations to atypical conditions
IDP01037
(
show subtarget assignments
)
0
work_stopped
STM2927
16766233
surE
stationary phase survival protein SurE
253
potential drug target /
Conserved Gene / Pathway
Phase 2: March 2008
2V4N
100%
Salmonella enterica
Cellular processes
Adaptations to atypical conditions
IDP02827
(
show subtarget assignments
)
1
cloned
FTT1508c
56708546
relA
GTP pyrophosphokinase [Francisella tular...
647
Drug Target
Phase 3: June 2008
1VJ7
20.1%
Francisella tularensis
Cellular processes
Adaptations to atypical conditions
IDP01255
(
show subtarget assignments
)
1
purified
BA_5132
30259616
yugI
general stress protein 13
114
Conserved Gene / Pathway
Phase 2: March 2008
2K4K
53.3%
Bacillus anthracis
Cellular processes
Adaptations to atypical conditions
IDP00848
(
show subtarget assignments
)
1
purified
SACOL1753
57286190
universal stress protein family
137
Conserved Gene / Pathway
Phase 2: March 2008
1MJH
33.5%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP00833
(
show subtarget assignments
)
1
cloned
SACOL2627
57286532
betA
choline dehydrogenase
569
Conserved Gene / Pathway
Phase 2: March 2008
3LJP
32.7%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP00436
(
show subtarget assignments
)
1
cloned
YPO3358
16123508
surE
stationary phase survival protein SurE
254
Conserved Gene / Pathway
Phase 2: March 2008
2V4N
79.9%
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP00803
(
show subtarget assignments
)
1
purified
SACOL1759
57286194
universal stress protein family
166
Conserved Gene / Pathway
Phase 2: March 2008
1TQ8
30.7%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP01111
(
show subtarget assignments
)
1
cloned
BA_1135
49035527
Major cold shock protein cspA
67
Conserved Gene / Pathway
Phase 2: March 2008
1CSP
73.1%
Bacillus anthracis
Cellular processes
Adaptations to atypical conditions
IDP01102
(
show subtarget assignments
)
1
soluble
BA_5424
49040749
Cold shock-like protein cspC
65
Essential Gene
Phase 2: March 2008
1C9O
74.2%
Bacillus anthracis
Cellular processes
Adaptations to atypical conditions
IDP00404
(
show subtarget assignments
)
1
soluble
YPCD1.48
16082736
virG
needle complex outer membrane lipoprotei...
131
Virulence Associated Factor
Phase 2: March 2008
2YJL
23.7%
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP00699
(
show subtarget assignments
)
1
in_pdb
3ED6
3FG0
SACOL2628
57286533
betB
betaine aldehyde dehydrogenase
496
Conserved Gene / Pathway
Phase 2: March 2008
3ED6
100%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP02334
(
show subtarget assignments
)
1
soluble
FTT0391c
56707540
cspC
cold shock protein [Francisella tularens...
67
Drug Target
Phase 3: June 2008
3I2Z
61.8%
Francisella tularensis
Cellular processes
Adaptations to atypical conditions
IDP00630
(
show subtarget assignments
)
1
cloned
SACOL0861
57284322
cold shock protein, CSD family
66
Conserved Gene / Pathway
Phase 2: March 2008
2I5M
71.2%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP00627
(
show subtarget assignments
)
1
purified
SACOL0552
57285570
hypothetical protein SACOL0552
133
Conserved Gene / Pathway
Phase 2: March 2008
2K4K
40.6%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP00623
(
show subtarget assignments
)
1
cloned
SACOL2731
57285285
cold shock protein, CSD family
66
Conserved Gene / Pathway
Phase 2: March 2008
2I5M
68.2%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP04328
(
show subtarget assignments
)
1
cloned
CPF_1452
110798743
cold shock protein [Clostridium perfring...
69
conserved gene; putative drug target function;
Phase 4: April 2009
2L15
56.3%
Clostridium perfringens
Cellular processes
Adaptations to atypical conditions
IDP00610
(
show subtarget assignments
)
1
cloned
SACOL1437
57286088
cold shock protein, CSD family
66
Conserved Gene / Pathway
Phase 2: March 2008
1CSP
75.8%
Staphylococcus aureus
Cellular processes
Adaptations to atypical conditions
IDP02020
(
show subtarget assignments
)
1
crystallized
FTT0245
56707402
usp
universal stress protein [Francisella tu...
278
Drug Target
Phase 3: June 2008
2PFS
20.5%
Francisella tularensis
Cellular processes
Adaptations to atypical conditions
IDP02706
(
show subtarget assignments
)
1
cloned
FTT0470
56707612
apaH
diadenosine tetraphosphatase [Francisell...
275
Drug Target
Phase 3: June 2008
2DFJ
37.8%
Francisella tularensis
Cellular processes
Adaptations to atypical conditions
IDP02351
(
show subtarget assignments
)
1
cloned
FTT1112c
56708190
rpoH
RNA polymerase factor sigma-32 [Francise...
292
Drug Target
Phase 3: June 2008
1IW7
25%
Francisella tularensis
Cellular processesTranscription
Adaptations to atypical conditionsTranscription factors
IDP01967
(
show subtarget assignments
)
1
soluble
STM1789
16765130
hydrogenase 1 maturation protease [Salmo...
198
Drug target motif; Conserved; Drug target functions
Phase 3: June 2008
1CFZ
30.8%
Salmonella enterica
Energy metabolism
Aerobic
IDP01909
(
show subtarget assignments
)
1
soluble
STM1536
16764881
putative hydrogenase maturation protease...
202
Drug target motif; Conserved; Drug target functions
Phase 3: June 2008
1CFZ
30.7%
Salmonella enterica
Energy metabolism
Aerobic
IDP02111
(
show subtarget assignments
)
1
purified
STM3694
16766979
lldD
L-lactate dehydrogenase [Salmonella typh...
396
Conserved; Drug target functions
Phase 3: June 2008
1AL7
32.6%
Salmonella enterica
Energy metabolism
Aerobic
IDP02007
(
show subtarget assignments
)
1
purified
STM2330
16765657
lrhA
NADH dehydrogenase transcriptional repre...
312
Drug target motif; Conserved; Drug target functions
Phase 3: June 2008
3ONM
38.8%
Salmonella enterica
Energy metabolism
Aerobic
IDP01730
(
show subtarget assignments
)
1
expressed
FTT0871
56707975
gpsA
glycerol-3-phosphate dehydrogenase (NAD(...
332
Conserved; Drug target functions
Phase 3: June 2008
3K96
43.1%
Francisella tularensis
Energy metabolismFatty acid and phospholipid metabolism
AerobicAnaerobic,Biosynthesis
IDP04146
(
show subtarget assignments
)
1
expressed
YPO2147
218929248
dadA
D-amino acid dehydrogenase small subunit...
434
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
1PJ5
19.1%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP00569
(
show subtarget assignments
)
1
soluble
YPO4016
16124139
hutH
histidine ammonia-lyase
510
Drug Target Function
Phase 2: March 2008
1GK2
77.5%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP04154
(
show subtarget assignments
)
1
cloned
YPO4017
218931008
hutU
urocanate hydratase [Yersinia pestis CO9...
563
conserved gene; putative drug target function;
Phase 4: April 2009
1UWL
86.3%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP02561
(
show subtarget assignments
)
1
purified
FTT0714c
56707833
kbl
2-amino-3-ketobutyrate coenzyme A ligase...
398
Conserved; Drug target functions
Phase 3: June 2008
1FC4
62.1%
Francisella tularensis
Energy metabolism
Amino acids and amines
IDP02643
(
show subtarget assignments
)
1
in_pdb
3RUY
GBAA1154
47526421
rocD
ornithine--oxo-acid transaminase [Bacill...
396
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
3RUY
98.7%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP04283
(
show subtarget assignments
)
1
expressed
YPO1971
218929083
hutG
putative N-formylglutamate amidohydrolas...
268
conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP01218
(
show subtarget assignments
)
1
expressed
BA_3712
73919984
Histidine ammonia-lyase (Histidase)
505
Drug Target Function
Phase 2: March 2008
1GK2
42%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP04050
(
show subtarget assignments
)
1
purified
YPO1765
218928887
hpaF
5-carboxymethyl-2-hydroxymuconate delta-...
132
conserved gene; putative drug target function;
Phase 4: April 2009
1OTG
67.4%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP01041
(
show subtarget assignments
)
1
purified
STM2971
16766276
sdaB
L-serine dehydratase/L-threonine deamina...
455
Conserved Gene / Pathway
Phase 2: March 2008
2IQQ
16%
Salmonella enterica
Energy metabolism
Amino acids and amines
IDP02094
(
show subtarget assignments
)
1
cloned
STM3598
16766884
putative L-asparaginase [Salmonella typh...
347
Conserved; Drug target functions
Phase 3: June 2008
1ZCF
68.9%
Salmonella enterica
Energy metabolism
Amino acids and amines
IDP04721
(
show subtarget assignments
)
1
expressed
YPO1289
115347051
conserved hypothetical protein [Yersinia...
380
conserved gene; putative drug target function;
Phase 4: April 2009
2Q18
16.8%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP02251
(
show subtarget assignments
)
1
cloned
YPO1201
16121494
putative amino acid decarboxylase [Yersi...
768
Involved in virulence; Drug target functions
Phase 3: June 2008
2VYC
51.6%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP04037
(
show subtarget assignments
)
1
in_pdb
3S52
YPO2082
115347800
putative fumarylacetoacetate hydrolase f...
218
putative drug target function;
Phase 4: April 2009
3S52
100%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP04722
(
show subtarget assignments
)
1
purified
YPO1357
115347116
ltaA
L-allo-threonine aldolase [Yersinia pest...
339
conserved gene; putative drug target function;
Phase 4: April 2009
1LW4
46.5%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP02640
(
show subtarget assignments
)
1
purified
GBAA0609
47525887
aspA
aspartate ammonia-lyase [Bacillus anthra...
477
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
1J3U
70.6%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP04008
(
show subtarget assignments
)
1
cloned
YPO0906
218928079
gcsH
glycine cleavage system protein H [Yersi...
128
conserved gene; putative drug target function;
Phase 4: April 2009
3A7A
75%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP01830
(
show subtarget assignments
)
1
purified
FTT0407
56707556
gcvT
glycine cleavage system aminomethyltrans...
358
Drug Target
Phase 3: June 2008
1VLO
47.9%
Francisella tularensis
Energy metabolism
Amino acids and amines
IDP02829
(
show subtarget assignments
)
1
cloned
GBAA4382
47529677
bfmbB
branched-chain alpha-keto acid dehydroge...
439
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
3DUF
38.4%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP02647
(
show subtarget assignments
)
1
purified
lmo0537
16802580
allantoate amidohydrolase [Listeria mono...
423
Presence of Protease Motifs; DNA binding Motifs
Phase 3: June 2008
3N5F
38.1%
Listeria monocytogenes
Energy metabolism
Amino acids and amines
IDP02466
(
show subtarget assignments
)
1
purified
YPO1771
16122025
L-serine dehydratase [Yersinia pestis CO...
454
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Involved in vir...
Phase 3: June 2008
2IQQ
17%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP04493
(
show subtarget assignments
)
1
cloned
YPO4089
115349677
pyridoxal-phosphate dependent enzyme [Ye...
320
putative drug target function;
Phase 4: April 2009
3HMK
36.6%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP04470
(
show subtarget assignments
)
1
cloned
YPO2306
218929398
putative amino acid antiporter [Yersinia...
463
putative drug target function;
Phase 4: April 2009
3HQK
26.1%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP00831
(
show subtarget assignments
)
0
work_stopped
SACOL2545
57285227
sdaAB
L-serine dehydratase, iron-sulfur-depend...
226
Conserved Gene / Pathway
Phase 2: March 2008
Staphylococcus aureus
Energy metabolism
Amino acids and amines
IDP00830
(
show subtarget assignments
)
1
purified
SACOL2544
57285226
sdaAA
L-serine dehydratase, iron-sulfur-depend...
299
Conserved Gene / Pathway
Phase 2: March 2008
Staphylococcus aureus
Energy metabolism
Amino acids and amines
IDP02417
(
show subtarget assignments
)
1
cloned
FTT0812
56707923
gcvH1
glycine cleavage system protein H [Franc...
126
Conserved; Drug target functions
Phase 3: June 2008
1ZKO
40.5%
Francisella tularensis
Energy metabolism
Amino acids and amines
IDP04466
(
show subtarget assignments
)
1
in_pdb
3NTX
YPO2161
115347872
ansA
L-asparaginase I [Yersinia pestis CO92]
338
putative drug target function;
Phase 4: April 2009
3NTX
99.7%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP02743
(
show subtarget assignments
)
1
cloned
GBAA4383
47529678
bfmbAb
3-methyl-2-oxobutanoate dehydrogenase, b...
327
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1UM9
52.9%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP02745
(
show subtarget assignments
)
1
cloned
GBAA4384
47529679
bfmbAa
3-methyl-2-oxobutanoate dehydrogenase, a...
333
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1UM9
41.7%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP02210
(
show subtarget assignments
)
1
cloned
FTT0980
56708072
hypothetical protein FTT0980 [Francisell...
413
Conserved; Drug target functions
Phase 3: June 2008
1FC4
26.4%
Francisella tularensis
Energy metabolism
Amino acids and amines
IDP00744
(
show subtarget assignments
)
1
soluble
SACOL1563
57284661
lpdA
2-oxoisovalerate dehydrogenase, E3 compo...
473
Drug Target Function
Phase 2: March 2008
3URH
37%
Staphylococcus aureus
Energy metabolism
Amino acids and amines
IDP04462
(
show subtarget assignments
)
1
purified
YPO1939
115347664
putative glutaminase [Yersinia pestis CO...
340
putative drug target function;
Phase 4: April 2009
1U60
38.2%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP04464
(
show subtarget assignments
)
1
purified
YPO1972
218929084
hutI
imidazolonepropionase [Yersinia pestis C...
406
conserved gene; putative drug target function;
Phase 4: April 2009
2OOF
54.9%
Yersinia pestis
Energy metabolism
Amino acids and amines
IDP01980
(
show subtarget assignments
)
0
work_stopped
STM3054
16766355
gcvH
glycine cleavage system protein H [Salmo...
129
Conserved; Drug target functions
Phase 3: June 2008
3A8I
98.5%
Salmonella enterica
Energy metabolism
Amino acids and amines
IDP00700
(
show subtarget assignments
)
1
purified
SACOL2656
57286560
arcB2
ornithine carbamoyltransferase
336
Drug Target Function
Phase 2: March 2008
2W37
63.3%
Staphylococcus aureus
Energy metabolism
Amino acids and amines
IDP02192
(
show subtarget assignments
)
1
soluble
YPO0348
16120683
aspA
aspartate ammonia-lyase [Yersinia pestis...
478
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Involved in vir...
Phase 3: June 2008
1JSW
89.3%
Yersinia pestis
Energy metabolism
Amino acids and amines
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