Target   IDP90163

Stage

in_pdb   : 3JS3

Locus Tag/Selection DB Lookup

CD2217  

NCBI Protein Lookup

gi: 172044608   accession: Q186A6  

Organism

Clostridium difficile 630  

Common Name

3-dehydroquinate dehydratase (3-dehydroquinase) (Type I DHQase)  

Gene Name

aroD  

NCBI Gene Lookup

 

NCBI Annotation

 

TIGR Main Role/Annotations

 

TIGR Sub Role

 

Comment

 

Selection Phase

Community Requests  

Date Approved

Sep 24, 2008  

Justification for Selection

Potential drug target. Shikimate pathway enzyme  

Justification Codes

 

Priority

8  

Sequence Length

255  

(Subtargets)

 

pI

6.53  

Molecular Weight

28.9 kDa  

Sequence

(Check Homologs)

MKRKVQVKNI TIGEGRPKIC VPIIGKNKKD IIKEAKELKD ACLDIIEWRV DFFENVENIK EVKEVLYELR SYIHDIPLLF TFRSVVEGGE KLISRDYYTT LNKEISNTGL VDLIDVELFM GDEVIDEVVN FAHKKEVKVI ISNHDFNKTP KKEEIVSRLC RMQELGADLP KIAVMPQNEK DVLVLLEATN EMFKIYADRP IITMSMSGMG VISRLCGEIF GSALTFGAAK SVSAPGQISF KELNSVLNLL HKSIN  

DNA Sequence

ATGAAA AGAAAA GTTCAA GTAAAA AATATT ACTATT GGAGAA GGTAGA CCTAAA ATTTGT GTACCA ATTATT GGGAAA AATAAA AAAGAT ATTATA AAAGAG GCTAAA GAGTTA AAAGAT GCATGT TTGGAT ATTATA GAGTGG CGAGTT GATTTT TTTGAG AATGTA GAAAAT ATTAAA GAAGTT AAGGAA GTTCTC TATGAA TTAAGA AGTTAT ATACAT GATATC CCTTTA TTATTC ACATTT AGAAGT GTAGTA GAAGGG GGAGAA AAATTA ATATCA AGAGAT TATTAT ACTACT TTGAAT AAAGAA ATTTCT AATACA GGTTTA GTAGAT TTAATA GATGTA GAGTTA TTTATG GGAGAT GAGGTC ATAGAT GAAGTA GTTAAT TTTGCT CATAAA AAAGAA GTGAAA GTAATT ATATCT AATCAT GATTTT AATAAA ACTCCA AAAAAA GAAGAG ATTGTA TCTCGT TTATGT AGAATG CAGGAA TTGGGC GCAGAT TTACCC AAAATA GCTGTT ATGCCG CAAAAT GAAAAA GATGTG TTAGTG CTACTT GAAGCT ACAAAT GAAATG TTTAAA ATTTAT GCAGAT AGACCA ATAATA ACAATG TCAATG TCAGGA ATGGGT GTTATA AGTAGA CTGTGT GGTGAA ATATTT GGTTCT GCATTG ACTTTT GGAGCT GCAAAA AGTGTT TCAGCA CCAGGG CAAATA TCATTT AAAGAG TTAAAT TCAGTA CTTAAT CTATTA CATAAG AGTATT AATTAA  

Inserted

Oct 15, 2008