Target   IDP90355

Stage

in_pdb   : 3N08

Locus Tag/Selection DB Lookup

CT736  

NCBI Protein Lookup

gi: 15605469   accession: YP_002889241  

Organism

Chlamydia trachomatis D/UW-3/CX  

Common Name

hypothetical protein CT736 [Chlamydia trachomatis D/UW-3/CX]  

Gene Name

ybcL  

NCBI Gene Lookup

884536  

NCBI Annotation

Note the PF01161;Phosphatidylethanolamine-binding motif  

TIGR Main Role/Annotations

 

TIGR Sub Role

 

Comment

 

Selection Phase

Community Requests  

Date Approved

Jun 15, 2009  

Justification for Selection

These targets are similar to actual drug targets and will be used mostly for cocrystallisation with small molecules. The more information we have about the binding sites, the better are the chances to understand how the drug works and what modification can achieve.  

Justification Codes

 

Priority

8  

Sequence Length

150  

(Subtargets)

 

pI

4.30  

Molecular Weight

16.5 kDa  

Sequence

(Check Homologs)

MQLTSQAFSY GRPIPKKYSC QGVGISPPLS FSDVPREAKS LVLIVEDPDV PPSVREDGLW IHWIVYNLSP VVSNLAEGAQ IFAVQGLNTA GEIGYCPPCP PDAKHRYYFY AYALDVVLSD EEGVTKEQLL EAMDGHIIAT AELMGTYEKD  

DNA Sequence

ATGCAA CTCACC TCACAA GCTTTT TCTTAC GGCCGT CCGATT CCTAAA AAGTAT TCGTGT CAGGGC GTTGGG ATCTCC CCACCG CTGTCT TTTTCT GATGTC CCTAGA GAGGCT AAAAGT CTTGTT CTTATT GTTGAA GATCCA GATGTC CCTCCT AGTGTT CGAGAG GATGGG TTGTGG ATACAC TGGATA GTGTAT AACCTT TCGCCT GTAGTC TCTAAT CTTGCA GAAGGA GCACAA ATTTTT GCTGTC CAAGGG TTAAAT ACTGCT GGAGAA ATAGGA TACTGC CCTCCT TGCCCT CCAGAT GCGAAG CATCGC TATTAC TTTTAT GCTTAT GCGCTC GATGTT GTGCTT TCCGAT GAAGAA GGAGTG ACCAAA GAACAG CTGTTA GAAGCT ATGGAC GGACAT ATCATA GCTACG GCAGAG CTGATG GGCACA TATGAA AAAGAC TAA  

Inserted

Jul 10, 2009