Target   IDP90915

Stage

in_pdb   : 3LXY

Locus Tag/Selection DB Lookup

YPO0493  

NCBI Protein Lookup

gi: 16120823   accession: NP_404136  

Organism

Yersinia pestis CO92  

Common Name

4-hydroxythreonine-4-phosphate dehydrogenase [Yersinia pestis CO92]  

Gene Name

pdxA  

NCBI Gene Lookup

 

NCBI Annotation

NAD-dependent; catalyzes the oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which then decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)  

TIGR Main Role/Annotations

 

TIGR Sub Role

 

Comment

 

Selection Phase

Community Requests  

Date Approved

Jul 29, 2009  

Justification for Selection

Predicted Essential  

Justification Codes

 

Priority

8  

Sequence Length

331  

(Subtargets)

 

pI

5.66  

Molecular Weight

35.3 kDa  

Sequence

(Check Homologs)

MHNHNNRLVI TPGEPAGVGP DLAITLAQQD WPVELVVCAD PALLLARASQ LNLPLQLREY QADQPAIAQQ AGSLTILPVK TAVNVVPGKL DVGNSHYVVE TLAKACDGAI SGEFAALVTG PVQKSIINDA GIPFIGHTEF FADRSHCQRV VMMLATEELR VALATTHLPL LAVPGAITQA SLHEVITILD NDLKTKFGIT QPQIYVCGLN PHAGEGGHMG HEEIDTIIPA LNTLRQQGIN LIGPLPADTL FQPKYLQHAD AVLAMYHDQG LPVLKYQGFG RAVNITLGLP FIRTSVDHGT ALELAATGTA DVGSFITALN LAIKMINNSN E  

DNA Sequence

ATGCAC AACCAC AATAAT CGTCTA GTGATC ACCCCC GGCGAG CCAGCC GGGGTC GGGCCG GATTTA GCCATC ACTCTG GCTCAA CAGGAT TGGCCT GTTGAG CTGGTA GTCTGC GCGGAT CCGGCC TTGCTA CTGGCC CGAGCC AGCCAA CTTAAT CTGCCC CTGCAA TTGCGT GAGTAC CAAGCT GACCAG CCGGCA ATAGCA CAGCAA GCAGGG TCACTG ACTATT TTACCT GTAAAA ACAGCT GTTAAT GTTGTC CCTGGC AAGCTT GATGTC GGTAAC AGTCAC TATGTG GTTGAA ACGTTA GCCAAG GCTTGT GATGGT GCGATC AGTGGT GAATTC GCTGCA TTGGTC ACGGGC CCGGTA CAAAAA AGTATT ATCAAT GATGCC GGCATC CCCTTC ATTGGG CATACC GAATTC TTTGCT GACCGC AGCCAC TGCCAG AGGGTG GTGATG ATGCTG GCAACG GAAGAG TTGCGT GTGGCT TTAGCG ACCACC CACTTG CCATTA TTGGCG GTGCCA GGTGCC ATTACG CAAGCC AGCTTA CATGAA GTGATC ACCATC CTTGAT AACGAC CTAAAA ACCAAG TTTGGT ATTACT CAGCCA CAAATT TATGTT TGTGGG CTTAAT CCTCAT GCTGGC GAAGGG GGACAT ATGGGC CATGAA GAGATC GATACA ATTATT CCTGCC CTGAAT ACACTA CGCCAG CAAGGG ATAAAC CTCATT GGCCCA CTACCA GCAGAC ACCCTG TTTCAG CCGAAA TATCTG CAACAT GCAGAT GCCGTT CTCGCG ATGTAT CACGAT CAGGGG CTACCA GTATTG AAATAT CAAGGG TTTGGC CGAGCA GTCAAT ATCACT CTCGGT TTGCCT TTTATC CGCACT TCTGTG GATCAC GGTACC GCTTTA GAACTC GCCGCA ACCGGT ACTGCC GATGTT GGCAGT TTCATT ACGGCA TTAAAC TTAGCC ATCAAA ATGATA AATAAC AGCAAT GAATAA  

Inserted

Aug 28, 2009