Target   IDP91046

Stage

in_pdb   : 4ECL

Locus Tag/Selection DB Lookup

EFE0004  

NCBI Protein Lookup

gi: 33355854   accession: AAQ16274  

Organism

Enterococcus faecalis  

Common Name

serine racemase [Enterococcus faecalis]  

Gene Name

vanTG  

NCBI Gene Lookup

 

NCBI Annotation

 

TIGR Main Role/Annotations

 

TIGR Sub Role

 

Comment

0  

Selection Phase

Community Requests  

Date Approved

May 19, 2010  

Justification for Selection

Putative serine racemase involved in synthesis of D-Ala-D-Ser, a component of vancomycin resistant cell walls  

Justification Codes

drug resistance  

Priority

8  

Sequence Length

712  

(Subtargets)

 

pI

9.41  

Molecular Weight

79.8 kDa  

Sequence

(Check Homologs)

MTKNESYSGI DYFRFIAALL IVAIHTSPLS SFSETGNFIF TRIVARVAVP FFFMTSGFFL ISRYTCNAEK LGAFIKKTTL IYGVAILLYI PINVYNGYFK MDNLLPNIIK DIVFDGTLYH LWYLPASIIG AAIAWYLVKK VHYRKAFLIA SILYIIGLFG DSYYGIVKSV SCLNVFYNLI FQLTDYTRNG IFFAPIFFVL GGYISDSQNR LSLKRSIVGF IVCFALMFGE ALTLHHFDIQ KHDSMYVLLL PSVYCLFNLL LHFRGKRRTG LRTISLIIYI IHPFMIVVIR LFAKLLHLQS LLVENSLVHY IAVCFASVVL AVVITALLSS LKPKKAKHTA DTDRAYLEIN LNNLEHNVNT LQKAMSPKCE LMAVVKAEAY GHGMYEVTTY LEQIGVSSFA VATIDEGIRL RKYGISSEIL ILGYTSPSRA KELCKYELTQ TLIDYRYSLL LNKQGYDIKA HIKIDTGMHR LGFSTEDKDK ILAAFSLKHI KVAGIFTHLC AADSLEENDV AFTNKQIGSF YKVLDWLKSS GLNIPKVHIQ SSYGLLNYPE LECDYIRVGV ALYGVLSSTN DKTKLELDLR PVLSLKAKVV LIRKIKQGES VGYSRAFTAT RDSLIAILPI GYADGFPRNL SCGNSYVLIG GRQAPIVGKI CMDQLAVDVT DIPNVKTGSI ATLIGKDGKE EITAPMVAES AESITNELLS RMGHRLNIIR RA  

DNA Sequence

ATGACT AAAAAC GAAAGC TATTCT GGCATT GATTAT TTTAGA TTTATT GCAGCC TTATTG ATTGTT GCTATT CATACT TCGCCT CTCTCT TCTTTT AGTGAA ACAGGC AACTTT ATATTT ACACGC ATTGTA GCCCGT GTAGCC GTTCCG TTCTTT TTTATG ACATCT GGATTT TTTCTG ATTTCC AGATAT ACCTGT AATGCC GAAAAG CTGGGA GCTTTT ATAAAA AAGACA ACCTTA ATTTAC GGGGTT GCAATA CTCTTA TACATA CCTATC AATGTT TATAAC GGTTAT TTCAAA ATGGAC AACCTT TTGCCA AATATC ATAAAA GATATT GTATTT GATGGT ACTTTA TATCAC TTGTGG TATCTT CCTGCA TCTATT ATCGGA GCTGCG ATTGCT TGGTAT CTGGTA AAGAAA GTTCAT TATCGC AAAGCC TTTTTG ATAGCT TCTATA CTCTAT ATCATA GGCTTA TTTGGA GATAGT TATTAT GGAATT GTGAAA AGCGTT TCCTGC TTAAAT GTTTTT TACAAT CTAATC TTCCAA TTAACA GATTAC ACAAGA AACGGA ATATTT TTTGCC CCAATC TTTTTT GTGCTT GGTGGA TATATC TCTGAT AGTCAA AACAGA CTATCG TTAAAA AGAAGT ATAGTA GGATTT ATAGTT TGTTTT GCCCTT ATGTTT GGAGAA GCCCTT ACTTTA CATCAT TTTGAT ATACAG AAACAT GACAGT ATGTAT GTGCTT TTACTT CCGAGT GTGTAT TGCTTA TTTAAT CTTCTT CTGCAC TTTAGA GGAAAA CGCCGC ACAGGA TTACGG ACAATA TCATTG ATTATC TATATC ATTCAT CCGTTT ATGATT GTTGTA ATACGA TTGTTT GCCAAA TTACTG CATCTG CAAAGC CTGCTT GTTGAA AACAGC CTTGTT CATTAT ATTGCG GTCTGC TTTGCA TCGGTA GTATTA GCAGTG GTTATA ACAGCG TTATTG AGCAGT CTGAAA CCGAAA AAGGCA AAACAT ACCGCC GATACG GATAGA GCGTAT CTGGAA ATCAAC CTAAAT AATTTA GAGCAT AATGTA AACACT TTGCAA AAAGCA ATGTCA CCTAAA TGTGAA TTGATG GCGGTT GTAAAA GCGGAA GCCTAT GGTCAC GGTATG TATGAA GTGACG ACATAT CTTGAG CAGATA GGAGTT TCTTCA TTTGCG GTAGCT ACCATT GATGAA GGTATC CGATTG AGAAAA TATGGC ATCTCT AGCGAA ATCCTA ATTTTA GGCTAT ACATCG CCTTCA AGGGCA AAAGAA CTTTGT AAGTAT GAGCTG ACACAA ACCTTG ATAGAT TATAGG TATTCG TTGCTT TTGAAT AAACAG GGATAT GACATT AAAGCA CATATT AAAATT GACACA GGTATG CATAGA CTTGGA TTTAGC ACAGAA GATAAG GATAAA ATCCTT GCAGCT TTTTCT TTGAAG CACATC AAAGTT GCGGGA ATTTTT ACACAT TTGTGT GCGGCT GACAGC CTTGAA GAAAAT GATGTT GCATTT ACAAAC AAGCAA ATAGGC AGTTTC TATAAA GTGCTT GATTGG CTGAAA AGCAGC GGTTTG AATATA CCTAAA GTACAT ATCCAA AGTAGT TATGGA TTATTG AATTAT CCAGAG CTTGAA TGTGAT TATATC AGAGTG GGTGTT GCTCTG TATGGT GTTTTA AGCTCT ACTAAT GACAAA ACAAAA TTAGAA CTTGAT TTAAGA CCTGTA CTTTCT TTGAAA GCAAAA GTTGTT TTAATT CGGAAG ATAAAG CAGGGC GAAAGT GTTGGT TATAGC AGGGCT TTTACT GCAACC CGAGAT AGTTTA ATTGCC ATATTA CCAATT GGATAT GCAGAT GGTTTT CCAAGA AATCTG TCTTGT GGAAAT AGTTAT GTGCTG ATTGGT GGACGA CAAGCC CCTATT GTCGGA AAAATC TGTATG GATCAA CTTGCA GTTGAT GTAACA GATATT CCCAAT GTTAAG ACTGGA AGTATT GCAACG CTGATT GGTAAA GATGGA AAGGAA GAAATT ACAGCA CCGATG GTAGCT GAAAGT GCAGAA AGCATA ACCAAT GAATTG TTAAGC CGTATG GGACAC AGATTA AATATT ATTCGT AGAGCG TAA  

Inserted

Jun 03, 2010