Target IDP91095
- Stage
-
in_pdb
: 3POL, 4FCU
- Locus Tag/Selection DB Lookup
-
A1S_1557
- NCBI Protein Lookup
- gi: 193077192
accession: NC_009085
- Organism
-
Acinetobacter baumannii ATCC 17978
- Common Name
-
3-deoxy-manno-octulosonate cytidylyltransferase [Acinetobacter baumannii ATCC 17978]
- Gene Name
-
- NCBI Annotation
-
- TIGR Main Role/Annotations
-
- Comment
-
- Selection Phase
-
Community Requests
- Date Approved
-
Aug 31, 2010
- Justification for Selection
-
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defective in KDO biosynthesis have a compromised LPS and are usually less pathogenic and more susceptible to antibiotics.
- Justification Codes
-
potential drug target
- Priority
-
8
- Sequence Length
-
253
-
(Subtargets)
-
- pI
-
4.85
- Molecular Weight
-
28.4 kDa
-
Sequence
-
MKHIVIPARF SSSRLPGKPL LLIHDRPMIL RVVDQAKKVE GFDDLCVATD DERIAEICRA EGVDVVLTSA DHPSGTDRLS EVARIKGWDA DDIIVNVQGD EPLLPAQLVQ QVAKLLVDKP NCSMSTLCEP IHALDEFQRD SIVKVVMSKQ NEALYFSRAT IPYDRDGAKR DEPTLHTQAF RHLGLYAYRV SLLQEYVTWE MGKLEKLESL EQLRVLENGH RIAIAVAEAN LPPGVDTQAD LDRLNNMPVE SFE
- DNA Sequence
-
atgaaa catatc gtcatt ccagca cgcttc tcaagt tcgcgt ttgcca ggtaag ccattg ttactt attcat gatcgt cctatg atttta cgagtg gtggat caagca aaaaaa gttgaa ggtttc gatgac ctatgt gtagca acggac gatgaa cgtatc gctgaa atatgt cgtgca gagggc gttgat gttgtt ttaaca agtgca gaccat ccatca ggaaca gatcgt ttaagt gaagtt gctcgt attaaa ggatgg gatgct gatgac attatt gtaaat gtacaa ggcgat gagcca ttactg ccagcc cagctt gttcag caagtt gcaaag cttttg gttgat aagcca aactgt tcaatg tctaca ttatgt gagcct attcat gcgttg gatgaa tttcag cgtgat agtatc gtaaaa gtagtc atgtct aaacaa aatgaa gcatta tatttt agccgt gcaacg atccct tatgat cgagat ggcgct aagcga gatgaa ccaact ttacat actcaa gcattt cgtcat ttaggt ttatat gcttat cgtgtg agctta ttacaa gaatat gttaca tgggaa atgggt aaactt gaaaag ctcgag agtctt gagcaa ttgcgt gtttta gaaaat ggacac cgtatt gctatt gctgta gcagaa gcgaat ttacca ccaggt gttgac actcaa gcagat cttgat cgttta aataat atgcct gttgag tctttt gagtaa
- Inserted
-
Sep 03, 2010
