Target   IDP91961

Stage

in_pdb   : 4EQ9

Locus Tag/Selection DB Lookup

SpneCM_010100005438  

NCBI Protein Lookup

gi: 298255041   accession: NZ_ACNU00000000  

Organism

Streptococcus pneumoniae str. Canada MDR_19A  

Common Name

ABC transporter substrate-binding protein - amino acid transport [Streptococcus pneumoniae str. Canada MDR_19A]  

Gene Name

 

NCBI Gene Lookup

 

NCBI Annotation

 

TIGR Main Role/Annotations

 

TIGR Sub Role

 

Comment

notes  

Selection Phase

Community Requests  

Date Approved

 

Justification for Selection

Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19A. Target will be studied with collaborators (Scott Gray-Owen, University of Toronto) for their ability to generate immunogenic responses against S. pneumoniae infection for the purpose of generating a novel vaccine. The structures will aid in understanding the immunogenic response for further vaccine engineering.  

Justification Codes

 

Priority

8  

Sequence Length

276  

(Subtargets)

 

pI

0.00  

Molecular Weight

30.6 kDa  

Sequence

(Check Homologs)

MKKIVKYSSL AALGLVAAGV LAACSGGAKK EGEAASKKEI IVATNGSPRP FIYEENGELT GYEIEVVRAI FKDSDKYDVK FEKTEWSGVF AGLDADRYNM AVNNLSYTKE RAEKYLYAAP IAQNPNVLVV KKDDSSIKSL DDIGGKSTEV VQATTSAKQL EAYNAEHTDN PTILNYTKAD FQQIMVRLSD GQFDYKIFDK IGVETVIKNQ GLDNLKVIEL PSDQQPYVYP LLAQGQDELK SFVDKRIKEL YKDGTLEKLS KQFFGDTYLP AEADIK  

DNA Sequence

ATGAAA AAAATC GTTAAA TACTCA TCTCTT GCTGCC CTAGGA CTTGTT GCTGCA GGTGTG CTTGCG GCTTGC TCAGGG GGTGCT AAGAAA GAAGGA GAAGCA GCTAGC AAGAAA GAAATC ATCGTT GCAACC AATGGA TCACCA AGGCCA TTTATC TATGAA GAAAAT GGCGAA TTGACT GGTTAC GAGATT GAAGTC GTTCGC GCTATC TTTAAA GATTCT GACAAA TATGAT GTCAAG TTTGAA AAGACA GAATGG TCAGGT GTCTTT GCTGGT CTTGAC GCTGAC CGTTAC AATATG GCTGTC AACAAT CTTAGC TACACT AAAGAA CGTGCG GAGAAA TACCTC TATGCC GCACCA ATTGCC CAAAAT CCTAAT GTCCTT GTCGTG AAGAAA GATGAC TCTAGT ATCAAG TCTCTC GATGAT ATCGGT GGAAAA TCGACG GAAGTC GTTCAA GCCACT ACATCA GCTAAG CAGTTA GAAGCA TACAAT GCTGAA CACACG GACAAC CCAACT ATCCTT AACTAT ACTAAG GCAGAC TTCCAA CAAATC ATGGTA CGTTTG AGCGAT GGACAA TTTGAC TACAAG ATTTTT GATAAA ATCGGT GTTGAA ACAGTG ATCAAG AACCAA GGTTTG GACAAC TTGAAA GTTATC GAACTT CCAAGC GACCAA CAACCG TACGTT TACCCA CTTCTT GCTCAA GGTCAA GATGAG TTGAAA TCATTT GTAGAC AAACGC ATCAAA GAACTT TATAAA GATGGA ACTCTT GAAAAA TTGTCT AAACAA TTCTTC GGAGAT ACTTAT CTACCA GCAGAG GCTGAT ATTAAA TAA  

Inserted

Jan 13, 2012