t]3.6-1h/data/swissprot/ 3GE1.pdbdupa 3G25.pdb'[html] [head] [style type="text/css"] body { background-color: #FFFDF3; } a { text-decoration: none; } #tabs { border-bottom: .5em solid #801010; margin: 0; padding: 0; } #page1 #tabs li#tab1 a, #page2 #tabs li#tab2 a, #page3 #tabs li#tab3 a, .page4 li#tab4 a { padding: 0.25em 1em; border: solid; border-width: 1px; border-color: #801010; border-bottom: none; #background-color: none; color: #000; } #main { border-top :1px solid #666; clear: both; background: #FFFDF3; padding-top: 1px; padding-left:1px; padding-right:1px; padding-bottom:1px; min-width: 384px; } #contents { padding-top: 1px; padding-left:2px; padding-right:2px; padding-bottom:1px; background: #FFFDF3; min-width: 380px; } #header { position: relative; width: 100%; height: 3em; min-width: 384px; } #header ul#primary { margin: 0; padding: 0px; position: absolute; bottom: -1px; width:100%; } #header ul#primary li { display: inline; list-style: none; width:100%; } #header ul#primary a,#header ul#primary span,#header ul#primary a.current { display: block; float: left; padding:4px; margin: 1px 2px 2px 2px; text-align: center; font-family: tahoma, verdana, sans-serif; font-size: 85%; text-decoration: none; color: #333; } #header ul#primary span,#header ul#primary a.current,#header ul#primary a.current:hover { border: 1px solid #666; border-bottom: none; background: #FFF3B3; padding-bottom: 6px; margin-top: 0; } #header ul#primary a { background: #FFFAE1; border: 1px solid #AAA; border-bottom: none; } #header ul#primary a:hover { margin-top: 0; border-color: #666; background: #FFF7CD; padding-bottom: 5px; } #header ul#secondary { position: absolute; margin: 0; padding: 0; bottom: -1.4em; left: 1px; width: 50em; /* a width is required for Opera, older Mozilla browsers, and Konqueror browsers */ } #header ul#secondary li a,#header ul#secondary li span { width: auto; display: block; float: left; padding: 0 10px; margin: 0; border: none; border-right: 1px dotted #AAA; background: none; } #header ul#secondary li a { color: #06C; text-decoration: underline; } #header ul#secondary li a:hover { color: #333; background: transparent; padding: 0 10px; border: none; border-right: 1px dotted #AAA; } #header ul#secondary li a:active { color: #000; background: transparent; } #header ul#secondary li:last-child a { border: none; } [/style] [title]Annotation[/title] [/head] [body] [img src="#icm/image/album/csgid.png"] [hr] [h3]2.7 Angstrom Crystal Structure Of Glycerol Kinase (Glpk) From Staphylococcus Aureus In Complex With Adp And Glycerol[/h3] [p]G.Minasov, J.Brunzelle, T.Skarina, O.Onopriyenko, S.N.Peterson, A.Savchenko, W.F.Anderson, Center For Structural Genomics Of Infectious Diseases (Csgid)[/p] [h3]PDB Code: [a href="http://www.rcsb.org/pdb/explore.do?structureId=3GE1" target="blank"]3GE1[/a] [small](deposited on 24-FEB-09)[/small][/h3] [h3]Structural data[/h3] [p][!--icmscript name="1" display slide=slideshow.slides index="Asymmetric unit" --] [a name="1" href="#_"]Asymmetric unit[/a] [/p] [p][!--icmscript name="2" display slide=slideshow.slides index="Biological unit" --] [a name="2" href="#_"]Biological unit[/a] [/p] [p][!--icmscript name="3" display slide=slideshow.slides index="Bfactor residues" --] [a name="3" href="#_"]Bfactor residues[/a] [/p] [p][!--icmscript name="4" display slide=slideshow.slides index="Bfactor surface" --] [a name="4" href="#_"]B-factor distribution on the surface[/a] [/p] [p][!--icmscript name="5" display slide=slideshow.slides index="Homolog superposition" --] [a name="5" href="#_"]Homolog superposition[/a] [/p] [p][!--icmscript name="6" display slide=slideshow.slides index="Ligand binding site 1" --] [a name="6" href="#_"]Ligand binding site 1[/a] [/p] [p][!--icmscript name="7" display slide=slideshow.slides index="Ligand binding site 2" --] [a name="7" href="#_"]Ligand binding site 2[/a] [/p] [p][!--icmscript name="8" display slide=slideshow.slides index="Ligand binding site 3" --] [a name="8" href="#_"]Ligand binding site 3[/a] [/p] [p][!--icmscript name="9" display slide=slideshow.slides index="Ligand binding site 4" --] [a name="9" href="#_"]Ligand binding site 4[/a] [/p] [p][!--icmscript name="10" display slide=slideshow.slides index="Ligand binding site 5" --] [a name="10" href="#_"]Ligand binding site 5[/a] [/p] [p][!--icmscript name="11" display slide=slideshow.slides index="Ligand binding site 6" --] [a name="11" href="#_"]Ligand binding site 6[/a] [/p] [p][!--icmscript name="12" display slide=slideshow.slides index="Ligand binding site 7" --] [a name="12" href="#_"]Ligand binding site 7[/a] [/p] [p][!--icmscript name="13" display slide=slideshow.slides index="Ligand binding site 8" --] [a name="13" href="#_"]Ligand binding site 8[/a] [/p] [p][!--icmscript name="14" display slide=slideshow.slides index="Ligand binding site 9" --] [a name="14" href="#_"]Ligand binding site 9[/a] [/p] [p][!--icmscript name="15" display slide=slideshow.slides index="Ligand binding site 10" --] [a name="15" href="#_"]Ligand binding site 10[/a] [/p] [p][!--icmscript name="16" display slide=slideshow.slides index="Ligand binding site 11" --] [a name="16" href="#_"]Ligand binding site 11[/a] [/p] [p][!--icmscript name="17" display slide=slideshow.slides index="Ligand binding site 12" --] [a name="17" href="#_"]Ligand binding site 12[/a] [/p] [p][!--icmscript name="18" display slide=slideshow.slides index="Ligand binding site 13" --] [a name="18" href="#_"]Ligand binding site 13[/a] [/p] [p][!--icmscript name="19" display slide=slideshow.slides index="Ligand binding site 14" --] [a name="19" href="#_"]Ligand binding site 14[/a] [/p] [p][!--icmscript name="20" display slide=slideshow.slides index="Ligand binding site 15" --] [a name="20" href="#_"]Ligand binding site 15[/a] [/p] [p][!--icmscript name="21" display slide=slideshow.slides index="Ligand binding site 16" --] [a name="21" href="#_"]Ligand binding site 16[/a] [/p] [p][!--icmscript name="22" display slide=slideshow.slides index="Ligand binding site 17" --] [a name="22" href="#_"]Ligand binding site 17[/a] [/p] [p][!--icmscript name="23" display slide=slideshow.slides index="Ligand binding site 18" --] [a name="23" href="#_"]Ligand binding site 18[/a] [/p] [p][!--icmscript name="24" display slide=slideshow.slides index="Ligand binding site 19" --] [a name="24" href="#_"]Ligand binding site 19[/a] [/p] [p][!--icmscript name="25" display slide=slideshow.slides index="Ligand binding site 20" --] [a name="25" href="#_"]Ligand binding site 20[/a] [/p] [hr /] [small] [b]Controls:[/b] [table] [tr][td][b]rotate[/b][/td] [td]with the -mouse[/td][/tr] [tr][td][b]drag[/b][/td] [td] with the -mouse (or with -key pressed)[/td][/tr] [tr][td][b]zoom[/b][/td] [td] with the -mouse in the left zone of the window: zoom-up, unzoom-down[/td][/tr] [tr][td][b]clipping[/b][/td] [td] with the -mouse in the right zone of the window[/td][/tr] [/table] [p](TIP 1: Ribbon can be coloured by [!--icmscript name="m1" # display setting: color by secondary structure color ribbon Res(a_) ribbonColorStyle=1 --] [a name="m1" href="#_"]Secondary Structure[/a] or [!--icmscript name="m2" # display setting: color by NtoC color ribbon Res(a_) ribbonColorStyle=2 --] [a name="m2" href="#_"]NtoC[/a] or [!--icmscript name="m3" # display setting: color by molecule color ribbon molecule Res(a_) ribbonColorStyle=1 --] [a name="m3" href="#_"]Molecule[/a]) [/p] [p](TIP 2: the ribbon style can be changed to [!--icmscript name="r1" # display setting: normal ribbon ribbonStyle=1 --] [a name="r1" href="#_"]Normal[/a] or [!--icmscript name="r2" # display setting: smooth ribbon ribbonStyle = 5 --] [a name="r2" href="#_"]Smooth[/a]) [/p] [p](TIP 3: the background colour can be changed to [!--icmscript name="d1" # display setting: white background BKGR = "white" color background rgb={255,255,255} --] [a name="d1" href="#_"][/a] or [!--icmscript name="d2" # display setting: black background BKGR = "black" color background rgb={0,0,0} --] [a name="d2" href="#_"][/a]) [/p] [p](TIP 4: [!--icmscript name="4" display slide=slideshow.slides index="default" --] [a name="1" href="#_"]reset the view[/a]) [/p] [hr /] [p]Datapack created using [a href="http://www.molsoft.com/icm_pro.html" target="blank"]Molsoft ICM[/a] and [a href="http://www.molsoft.com/icm_browser.html" target="blank"]Molsoft Browser[/a] technologies (patent pending).[/p] [/small] [/body] [/html]  3G25.pdb3GE1 a_3GE1B1  3G253csgid.pngPNG  IHDR3 GDsRGBbKGD pHYs  tIME(/tEXtCommentCreated with GIMPW IDATxy\uugFlъц$&0#2f 8رvo`̋gy1Il !ej0l hA@;4f43˽ y}>ܞ:uN_9ν-֔Lezs2*(S)S)S)S)S)S)S)S)S)STHEϓd29TѨGLMe8}zP; DM!0MA"0 jjR"aYO?upcr2eY$qq'ZO0M;D~i"shM;TvX,J$bm!D7J%0 3Y)T)U;]׽u%!~ o7 A2{Gەx'+rO3gF=8}}<KiZ0L"hdz6n\F{,QlzHsN15%4J 7XF M5,X0 ~w-yǏm^a#LMyqR 6P@kue&hlX˜9ա㓼^wo7}} OiaFt!L 0|YL4 *+եhkɺuiiQSN9z)H=uk(55 hj+Ѩ]ǥ޶ wg(e fQ3i>P ,K\5,Zk}]:t\.˞=s$ky"4 !B5|T /L3<5Сzhhuxb?Z[] -QFR)1СG٬C.E4Rnz*&jnmx'ܼy,زe떱 )듌"vPZk,2S\xaͥeD8ٽ{@!"0W;_1 B)) 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) ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???ϳ$??A2@<@C3@?@b?@b?@b??@@@x@x@ ???333333?333333???#~j????333333? 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\VV{LJTɍ8{c )ipaB}hL'Pd[{awEW~uC~ T&$eqQltwd Sw!\>  JqvIENDB`move=1000;blend=1000;3GE1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1]8?;? DC̃H! $??2~BA!C!̉ ??!?BA#@HdCH!_C?̉ ?$?!?BA $???C!C/!CÃC@$!R? ?A!) ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??A2@<@C3@?@b?@b?@b??@@@x@x@ ???333333?333333???#~j????333333? 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k^-tPA_۹3L_}4/dl_J$IENDB`move=1000;blend=1000;3GE1>?;? ) ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#T  %TүCQjVltW> LV<0DRYyi\Ŏ*x(u5mno9m>8Md˘,_3f㱒dr AP&3/`^my$YmjDضl5",XRV氹ƹV0zUͥ+aH$+aʞMBB vG,ZTheL@aB!r0 mWe&iu |֭i"I.~_iąznasx*S5E-"('^ [{w!\F)tjeK>^˸LU&-' a&&P0  ( €$8WRRIYCIQ Nt.,ۯx`j(P•Wa 4w1K4HC.fܮH$HfDɨ pFtcJ7󬮴LmsmSUU-7Eȓ}Xnw倩cnţ[Vӑ,UfZ7JM Qbлs8 o#%JO< JkrEdU,#ّ5 ]ɘ2Qc%-*CB!1jN@Xɼ+h$M< m@ xp0Pɔ CzfdC݇Md] ' LD[ VDn**UE׬u3Ρ0*iUD͂ -CN'*f8 GU; q޹#VG6.0&8ŋʩZselqqȪjBА$:YWu**.s6ʑp_}劑H'_lU"7W6Y?oZmH8$啵w"rD4Dly4iYeZ;H r2hu^*z{G>v׾V&(H ,٣ t,XRĚp=Uko}+nxS0'aav8(Q1CaYQZ 1CNdžN9e.8p dt+b$A@ 4|r #s3xxÌ>Ƥa1뿊D 102@D`Y0L IV*4 b@ EFrb0PTjI55t ALE\J\f7^ޞ2u&^LRaMi.qr$H &&H  4ܦk5No5eʕbZ^sM#N8"I'&jw_̮1FF~%d$[4&.eU{Zf1Px,QLdaJ'KDYQY4T7]rq!5Z(׊ Pz' l0¹7 &`2xc^yB ]TE ZR.h(Baw$&q0XqD &vp{YdW{M4'?binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???;/';$=?`3@;<@`=*3? 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) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$=?\#$RE@Ĕ)? 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An2YiQ"CN;yCΆds37#XPZ5SO7jm2?仺t;;RZR)NRTjPAR&JRRTY䒕']@0`Apa% >F '#ٙǜ9IT!5ֿojxڎh*ws`< )A)t;C 48 K$Yd i"H4FPFpx.R!qqpڔܘh M&M5:ІC!99r 9jT9C_ѳgv뻽yŃ9F{sU5lݵ0~#df3m ݚ^&f1χQt9{D b(C1کRT&鹗)RS:K>Dw9w&|I?g>zjc2,k^1[.\1aQaﻪֱkbZ(ִVTtֵlE-UN<*c JP, Yh$c`tP5NI)JK΃t JPJEJR A(*n p-@5T\ ..owws䧻?ڥWnn2APr".+?k'j p±?ٙ3QY{SRk&>fGkf}v3v߷SuSQm(2 ^;*?ي%ّkc֞Dd: <@2{6M1F5Qvj:!wwb\9A*s%H @ $@px_A8\cg9L! c3SW'n{omkyQviEwkjwmst>tks9J:ПA@, 7F@ A߇R!A &[< Dc1prcUkֱ0yF-L*t#;L(,-ֳAlc^#{3F|ݪF (i%&|!M[ucX k،L;{ݭݍVcяe,g9Id|hE AX "6j%I@./1F.!ό~<: S-SA_M4"@D @"CeJ*5idM,,M 4@PJR$РHEgB- !wB q6fuS#3̎Uߓ+icZA( Y6 Ja\YjwݎQdΊ?O{EB0F6xֱ ޽oDU5fgcP%)I E)RRHѳH6!!sCRRz+AЃdrUI#{3Q&΄%.L @I$YjTM@;u~@& @&&8&8&8@& @&&8&8&8`:888 a@ bccc@& @&&8&8&8qqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqq#  44$ yT(W#: 84A04Ap`t*"X0    <%gi*I$ӭލ_‹,X<FG^PNK;)<Βxо~1 Hzr%V>PAQ%igUH6Ɇ ]ȑtxKSƌC6hތZlmRGߑ V(Ӡ@ˌV9B0txԱ NW" 4Itqq3?$p“FbRX@Ʋx78S<.3OG(Xg䁩U+J!!vDC<(@p@i K1rȊ$[?$` PA -nʕo74n(XXdHHQҥ$G@@`&ΣFxӥ'MmLgyT0j &,4xHTYLlcg.쏥@@g[R7ӧ\2&,^"BIΚdP" <ȱd.ؙL:N@XTy1bba`@ etky#y 6"cH]9!P`.8qt ;̏4i1 $$@, $L5ѽ3Qh &=\eή<" C( dQbDӦqTD_# Lxɗ.]LHif: d,rLU$ ṣu`Hq 1:yH4HDCDIPӉegU1. 2 @XEsɢ4**H# Z$Πpx`!5Q<4B5gj9d#(Xa~TAX P* jYeM!qp8  0.);L%0c(DasI,k4%4XP*(} dGu? ਉ'<ҺX%sF2 vGH-~mmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmbinding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G253Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@??+3G25AfffL?p}-+3GE1Afff333?p}/?me$??@4@&D@@ W?`v?`v?`v??@@@x@x@ ???333333?333333???#~j????333333? 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I$HIHHHD"B@HI#qWWW WfW#"!'As binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??@/@|F@n!? 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?TUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUT 7 ee j JZj#P_*DTDT(T*RUTJA֪EGJ*U#֗TZ֠TkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#fWWW Wf#ēCUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUPbinding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??@@3#?@lg.@?????@@@x@x@ ???333333?333333???#~j????333333? 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X+y\Ԗ$ɩVGDy sF RIDAT'P_NQDUuo yYdI!0Vmoi vN7hh FBVT-q:IY΂`4a8z 8އzh0'Ӫqɗݼ9_ k')@cc摒|2NXX4!w#;Ц3j()~ָkkk2eJZӋ[k㚌54MZ"NQ~9EBm1pDAjeStVwg2qWYS(V,_xtj3*;$3jN)"@74uvpʻ(-%5м./zC Vnh8.;DnaHHɴyGyT+Rv N{?j>i*̥ϛO(J}ve%aS:$H4Hխf¡{cݺu3~0=15SqA G,NUw2KN@ G[(y\KN$9 8W q=]:e7ϮZ( fthѳ\+nR&=% 2-/ Z9iT'I_qi.4u9',U3Z?c9k#m%dh7۹s9mh_YOL("s~olLhx u~~+{رMZhlC75>wYk-=2vɘ7|3555e"6kO6x&-9봫q:6.7tXE\` s㙴A74O;Yz5{v]zʥ]b䳍U Q {«dOo8껖35ckײv.޳$(_}\94>ӛHձĀta7r9YH8Hs($by7M't'b'ʀCqaz* X-P<7*|i ضg<.J0x A{<2eaZ<^O>- nսYjnIa3ڎZw .gDyke1&7N94 bU,tO 4F7T!b:pqN3}|i|<G6J q(.6l{6K=?X!B`t[w M-uxEkOQ$ٖj\L3;Akc,oKbӎhl9Dc࠳W\P [( ÊbP8!D2H5$.)Hݯ%bxYrJ@SS.?r} Z^4RÀڊ &qP=$o+^|;V c-=n$G+FNs>ݯy}'%mpEǸf'0L _N>)eiЏg݈%ǎ<%!Ęp|w̛u.x;y|c_LӰ kЇ1I,kח\um躊|Vp ;Ƅ$ٺ5OO^K'K)дmYMKZF̉SPV4ʮ!.iϗ܍fJ(b󓤔پØ$eIFQvEf+XH.'CcmY ER0eK=$I?XhۊcU-ڕw㼛?`ւaV.fD P'"rRxs HER(̟V}XnMȒH W#\jl~xk2ܤ-ce4]o574 ;*69vj.uӵakz571}|$!e5}<l9q#-py_r{_.r;CA $WgΌ$ퟭ{^raYSqy?x;,&EviWh1S|CEv IDh|=.jYz#ߘ$2<=[ȒoqyܺkSB 6mq%(HcktxGc_+˞Ss@ `'9U1M}Č1y2l6 &(%;(.qmݫ/57hJ5O8$;ӗ`w-=>W[%srLɅ9T.9 Gv> x\>$Y4 ˾r9@~iG`߾fN-?^7cBpj4q9v!:<Vm[o=r?kxݼ>Z:~PxġXihp}/sUA^ʎ&. ٷgVT;aGi1k` x=(bau97Mz Cwr9a?da1$iT Ny ە)w_#kŨV#ꜻLIENDB`move=1000;blend=1000;3GE1U7?;? ?S?UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUT 1 ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTJ֠֯iIP_P_ԏA֠G֠QDZUOZ]j֠ZUUSZ֤֩Z֠Z#Z[ZUOTTuUԏAP_ZZj#P_R5(jUT֪?j /_U5jMjuUZ_j *TZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#YWWf#?UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???ɇ$??`fv6@9@@,$@?????@@@x@x@ ???333333?333333???#~j????333333? ףp= ?333333???@???333333?333333? xLigand binding site 4.-PNG  IHDRc IDATxw]e934LzFQ^EYRO]W ʲ+ Ow5(Ő.IHLHdҦqܙSo {y=}Ϸ @҂i4#nƈ#LK~_!tT[P9iJ(fÌuQn J %98OZ0d&ÌJqB`=2{>?A||^^ao#`Ra(!h8? !E܈5K?FП6zx<xX,J<CKN[hhBC׽i'C)  L;᜽|6hBG:i:iPޤBJ 4iklZjE;bMBC*EDRZ{2O(ʟL~N1~_5l݃Fj쇪j[*$=oJ\@p9WG-y'Ð{ē.TVyShI;X7,6S{bψR>>aG(,G^w Nk)ӧKil# 姭t\ yN[q7B@T)D:s08K/`g͖Qq+szhK>{|=cWXcN[%{5ݑH`j| rKylݳq}⢛ih XK݃ix;Ղƣ51UL:Eut:me /n@kFtʹ hj=knB-:?u_B9a¡0`PFvbsHuc14GQU6$^ݏ}k,}4 zc--Rl<4y9ŀE@GO֎>*ݑ*Kg'1 KOY{7csgbs&0 t?< <0X!KHeyyu)!j|d䅬ZQ۸Wz_C)'{ƉDQH\$~R`քp{фnj7yxx0vasDC!Q(.9>b1X 40MsԺӒxpc2>4Mуq gdlG6Շ`\"r:<~)%RISH)КkF|o崥U[mZ#36ј  41͑^c ̈́j9%gk:#X($/HOu9P!P }4#/7TyPRv:e Bhis C8%ӌcچ >RDb]4^ r-"?؈0y,\4M#б#dAuSsdۨ7Mh%% {7}RtGQJ`{#Pg'fleRL{0w*WqzL߿# /Cd/a芴Ռ)My'Dn"Q9B2iHvFS<n1 :[a Ĕ&>o ]g jgB%<ssn^A=G~K0w}7One'd)#!Lm -q_Ia9eZR}Z8܌mWk3P>:i&o|ݷm6uM7 ͛߱cڲeG?&r?3 fNYfM]y_}A}-5rZR}ZR}۬)Ԭ)oV|d:jQHMPMnze]6lЗ xwsww߭vܩw^9{.3sR8ɳʸ?u[gt<&fO]+hl$7R|#|˟=T5)￟ m#nA2EV\2… ݿ;gV"tEK91wlA)}?NrҢį\ȡcopWᗿI"! }F{Mx饗X&y" ))$'\/[G4a3wٮqƍ<#|Ts-r>V(ƻz^cנ'(\͵!8c".Rjjjxy{6?tttӟ4:rz]nDmqV|$]R 3F{Wn`ٜ n:}Uqʙ477gG-hkkVx>pt'Swj?-u40|[7ҺH9,֮]˟lu7j|a=6M8#p~Ìs8M /v\x≬CII w=#ÈZa(geV`iOU3X_Ơ $dMǭ/%\3W-b%[ݸq#w9PN|O=pn8zc8TKCkiur+YG#K/;@ u]ahl ^)AK{?=N xAJZaX |f9UM^-aW}!dCBÆ 4v[]~^뮻e˖/|!s> afo}q\AZJԊy96Y9.)1]_{Q}c _wu6 }+ /_r95$]EsՉu_J3c$ 2aZt} Dx<;"8R=N[:prKG2K/y_ŋ LzAfQy,I`=282۷o+2O,덶kW߬ K.p_κu#ӀN4D;A)WXS,Z;ik)hǎ29Cyώã8C#FTd YN4ԵޡrNdT̴+TTn8Z]Dvg) hϣFo}kL}oٲ믿~Lf JvKeU;Il$vu㯫c$*J=N< ̻VrS/+7y9+cLxC)GA4nM=uG ϡr+yA/'[zֱJ8, gz#&҆q1w} M42-±92R^̜Sůk:::hjjJx4]'nDlOBA8Gw}, [q5[u=N}q>~1/D0;i8EcK]=m(]yN&,] 0w*ۗvGGw[mp*E栬x:e)/Ay b,22_mB)p҉68s)0w‘M (JKKi8™m6n馔{r{W]Ͷheӝ ;il@[, PAtTTT<`&5#k쩎К-E(8$w/glڴH\w6H{Wu6D[g2Ҁ7 r,. 鱮APq˙L(׿]Gسg7|#w|ky >5B}_orO0_~ef͚Xbp5]r~c͛Ä%>Ϻz蓪>GS>cs=IH,%3p}vZ[[?1w+)R N]oγ>W2yNnu'\A4୘}3zc2 44N5fm۶m6j֬Y+ mgwE8t`p `U M86wHhH:[F][JvODU&KFqdFtT,ۯo#D+2|'!{衇PJO3wqI0(!4嶝>uMʔ"ɷ^g yXׯglܸ_|o}+-YWW/P LykߘOO>(N$^Pj\/S?g̛֭7j@'xbL[{k(ʟBhr\S\zAjf<_Β; `0lqLiie1\yW)^TJc$^t %1ZymSdi7>-melD[uF*{io!d-DU`nUuuX) IDAT4sBbQN5MZH+xtgkvELt2=1pYglu=o`g]Krf +p(].>PD@ڈǣqͲMق%&̍ $^gGVoi敹D:yqˆ`9HJ@_b=u|bxRp[>b^}J^2x GKx$t7YBK)f0yto;e/ϣlx@Uk,,t&RJ*UK`I ͎)"]EPY&ewq!i&j7~f ~r_=QOYS 7b:ҨSY:$B?)Myj9jɨ )t@{UwA*#5R(7t692q\׍~_ҹNˆ`BK˳7cUjc4S2f*Iy`bf{2\f)= gq~SPǁTN=2E,`S>ص/6]lJa3gڙ䆋R7vG:P p4fZrP\. hh9bDD^scHYMh,>s/ӸgO]r7x=~FD6QRXah:n≄p ^ݏ)M:[sguWJBB(A܈Z!l4`2R7=Y / Au>/=;0?(R(> رTΞ{-+t4UD:RrԾe(^|)E18Ͼ?qWEe8tl8Oǽ֣{EyM1&L筼ׇ:ixCVd|^BAx@IA%C|aG/<8ubJI>鋫/C5[Sn i^9X ,#4H< & 7ţz-hES#ot9)S{*)M,V:]>fSe 2ݤT߱}jFoz@6Gޔ'wt&BI fZ;1MkeR^޽m(3$1Hprz8tX5d X'XY#X<d*>7\e k(\f趴g5fq47ͅ3%` wӌ'<ޘ)K(+g˶GKmse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???)!$??@@O@yi ?@?@?@??@@@x@x@ ???333333?333333???#~j????333333? ףp= ?333333???@???333333?333333? xLigand binding site 5@PNG  IHDRc IDATxy|u3&iӤiIKPRr BUDQ""""_AQW""徏Z(%ϴMs7wNdlZW1gv_9-`!(#ǔ\8*Ɔm/Z_zȲ"+Ȳ,)tE/O:nW*fR:a}O= .['=~t,MӐeÍודf nW\2RPNvz$uRt @ qng9y<$$@bOFǢ S'E? hz YRֆV$4ոIKر ;hni";#Hم9\;HKb jG(܁ۙ@ Z:3&kbGo$P+M, @:B'?wr)aH݅,uqgUT-"u YVxeydžt'Uƍ$ B^ǘ(^~h6eDi(-7VPYS uWdLPď@Go@c0H`[ r3wRr{蓑^Z(s,Cm8a5t!t@֑kϝlv}L  -7Dmk5}mm((+l#GεRQqg^ #nCmoD0-揨 ]̿:pyhnV&Ed|c{hr'cS7y))nCRQcXH:tIf$harr3siyRAHl/0)mi4"27ԓ $7ʲc8E8 y2&4]Cc2>(˗ϴ 0 3m ;?~/-muT7ٕ% ` )t8݇1N{vSp!ҼYx鸜 j6aڄ斲6!>yEhz :B!kCZϴRIn^h,Ls[u֐1ޚ fc#f'#-gըpL trId"txGG|}ߞ'@`m}q;0l%ŝNZJ5sX0s8o{H4 B'hl2&Qm)  o =5ÍeF-FZ H̘Ify'yzkK:wqTlpK$!!WPdy!hn—m>i1y9vfuH$œkϣz!!x/j]qL= $Q߰`'p+[?fJbƤ%dPY{;b˚םNG7+]x󣿌"mN|)-g-)S;Ig޼EAض}Ifi*~+YrUCDNv72h!GP+-uȒh,"+6@oX=OOH#I2$ Ixt[M ʞ?sHdR2xҼhzM`Bt9r=PruCY'x{_va<= 3pȆew~c.<8n$$ʫhh#k% 3es.lyz~i7 IȞCsЩi7S&!NL*pf+H|skVCSk-P+'/<)Ѱuʂ悹}x\i4Vq6|H4h aL%I28s nx.OXdM5TJgx\iUp0i,dņ_e@cdc/bCVIfm ?}}ԅWBG x5#͛eES4n! phӝoX8/݉sɊZݏl$Ę DBG [ѐCchz\c/ j,BLr Qd"c۰ (6@(/~wuIf1cшu'lO@0vShPY#:^/\qg ^ $WLۍqVbfO:`#jX21xa543Vb]i(L ܆@ uXoYBna=PT <-U 3U##a/mW*B$Z2|RS}t[/PB|9ϕgfKOu'Naj sPk}0kIBt:&t#~3ZXfn>:ϼ?\qM(6!D쌛kDQ$ i NDh$Ɍp:wiI녖ι_Z:m>HWC/X$2/^Z*i72cR_ƍ [DUՈu4]E5ddZrvs8-)eM˗j8A?`oD;kU6[ִ,x酖νl:g3Aw@9`א&qϿےy|#e5uQ+(MAse5 2Փjmk<~{-]~7HH$d$"Iijg\Crzs/ '+FʓJyCT|-6|!e4ƺ`eL%6;6 Á@dTpZ?tGŌ:%| Q4-fx5H,BENVUCu1F&F#]s@z $1gZF3!+#f*Jv'L_?{%>Ѕ'ͻB7ߍm<~1w)D4-Maql> C7Co_5J4%A‘ ;liwyDo\q247͜rYYjrtuO\&[kzK%Irhj0hz `fPTHh w wtC6 &E G#h1*cGtPw!I-9m} @Q5IWB{)*#N8&rH$L$! nʞ#6z(UPt:VB2RHy"@;Tͭ l=z'پX19qN) ,qI(țf=?RywbS<)̛kX2GlHT|l:B>L@s{ݰo$-%z]^ϝ%f/Ů8?o`\dRRQ8!݌q(/:{ 5&yY$Q1_u8vw|緖OX Ps8pW7a)œl#;oNJ9.bGBQl])yp:ܤz[p˿uyV~#3Zы8qk`Fk34tX_ҋ8 q)@dCv u> .cc@$"=5֎%8.s 1k 𐖒E(f邳ho<"ؾ/.\ԷSs,}ˤq-+mE٣CCH5aotVE8X݁anwpoLD oKZ3R͹Nl)"nW;Hf|h,B$DEhl0 Ɏ(_JcYdZ;롫v=}'Vkeĉ'6wpkHH{*̥46;4$qۯ.3T=1aBj Pcs{]04p` PܸQQ m,^p*7~;y_'PO:ͻ߱VV3iZ}nSdƢ"!уD0sIj[/:ZhjeM̘$YPiS]̂g0$>zc6LMK-i eM>ez|mSs% Y}q$ "0m~"Q#=89́kuz?!Ҽt\0}tżӉD Cv̗m ]3-!qRPnV斜 ,xhwr qB7>r;jN:RL4o&NÍp{!6aY{g>Q4 2j wMٮ T=إ Ns[-,38kNF5$IEچ@blrzۍ KOq^$I>рq9S7 GxËewwHy+?~)X ]4eUBYݻN}R`f"vmd5ӼY( Mdw>DAꞤ]0s+u`B`Hlvk@: ͍nw o^~3?y0:qYVޏW; o,k/2~`K=DNn-=4$dn. .' r)׏:vwo _ v`^7VT(3gKd-"tJ!(.K+>,,p8nxlgժU\{^e˖::qɊa9WE12]qٯ%Yyotx1۾S敜ۙ+/]0ֽ0Y&7saw_`%iPT"ۨbotx\5Dp\x=^^/??6I`bɶ3o?Ee☦Ѱ/̙g9qy?Aͽխxxϒ9FMY Nfuh{ >i ij쩧06gxš:mNz]vМ ؒay/up\`EQp8V}P(ȏ~ݩ xӬBOА$9, IL<[18>wy'cƌkt{0HGIg.J7Hxo_GA'!E5#@U.`pvn6dW:v Z=3YASX׉? -U(KP^Yƿ5Hwuݖ1MN1V 1.o;)t@⍂ Ke/y8Tlt"7U0&{Ґ:3z3`+9݀ F(Ռ"ϡGqQaKD($  XL%;soYھ4 La"V<FbE44-J#G^n&Yf \2KIJXYB`Ø99'}ňaQ5L; 7q:<~\DLbZ )Esh뫃 nARYm@2R]l__Iۅ:5̔ЅN$6܁_B;QըK}Mt1 UP*j0‘^w f:T~w!N9(ۑBEqXp:^9i1&3]F2n i^xQtHQ(j,B .)vpIЩۏnj' )/eX?"G+9&HġaDBB5v7)tԞ(,^Ëg=ļmfqB$NUA XXMqpz MtZj0V0iܬ: hh s5&᪼! 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Є#)و4ZLyy9.RJKK)SbӦM̛_Z:o:zagBL2`D" 2$y@3xzjYB)#6ꫬZ /|,D:.O5-Ν;f̙C`̘>M~soϨ#`m)襌DD i*Y|3m\G>Y|dY6k,DCmNfOP_u}sf"guvr+"B> {?qzbs1‚T:8*O&D!aCG& FC)F R8tՐ5N=spAP;pG/XL ,Y=`j9z~ūKĸB"(N`^#0K2,!t%ѫ&,IeF!;}q'-+o!͛e=7.ؿ!$@U~<>>> rpw|$'aJ W $'yp7ԭ3a`TUIf&M~g$g`}w3wY>uȲB'q^W(q i(.:N^x9XjPN6|4K<$"a(?s$4Rˁv{r3FTрǝY,(oO,#^Z}dƘ2(48 y˿؜D0u;9X0 7޾9^^oLAd`!u\ckrp6ݣV|2&s߼|jpGn[]@~ K~|4]ܪ4(KR2J/g-ְGIFA0܎ňVkv/ȊYˆʳnj,*-3o^=ز=$d؜ GDJ)# On(bG$`PJU<:gKs{Q,D3#$RDW.$)ؐ%=zEC)ʟuZ3xd@<`ׁ :0 _blAަV:"To`v0K*5vscV-x[ye_x':w~.0wu7|3sYh0L<?E]ԫݩ\qw}#趭mMxx\D]mu`BՍdML 8=u,%.3ad@32˞cX<>;TObKvz 6SYIsmAS!@`9p:<4R6l'ss{N'-%IfY?Ihnqֹj[D$" ]'v_委Wm^ \ߎqBFJ=nW>3]lEFj$c;y' G#6B727"W)`|+KknQAQ F)j! aWHq8/ӯ߇.40vuj0 MHϝ5 I[`j``@jZ: F:Aj6z+P[¶b#FbZWޒ~1*kOmC95Q]ʺ]4V#$ô{?}G\}#:V"5j jwZLW;GUhhDɱ;/9.#-GZ:WwQ!mVG([PmI+y`[ETP^OFZYц"n'jp6S/ ;cKaiw: Hfdlmse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??@<@̼5@?@Cݱ?@Cݱ?@Cݱ??@@@x@x@ ???333333?333333???#~j????333333? 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-LBRr1M@|Y$l:]gNJ{l-[Ɯ9sxBpC:=Lyˆ(l1^zXKyr3QiȚh(igUĉ{w}͛7+rxWJbj;9Bok4t4' rdce kr_|[뮣7qsւkq,RBPSDīIxͪX.&.KiU™3۞-ՅP0MQhzգ:N_ѣ `{aƌ!Rٰ]y8Rö!spi6D ##{NAcKk:8đ6m ! @CDT7~Y p.gJAJ}N\sX 9giy3}%<Ҕvr02;Cgys=[n'g|/~5kE-{_tUDb:.ɯ](TVowHc4U~drJ鼄=WE|9cRhi} N<{Y#Go_ɲr$ ;Uߐ'-3,3t\2WN.#'ϑgˉEY yLRd!sK"@Tg ^C[g#݁vZ{N<,Bn̟`V`k^y`\z56l`̙ݲI0ttY},6H^5VǤSީ )9\3\[۞wLRV[9E2PUQ}0s2|4JIK"՟SX1MSJ{ {rҽtփ̴̜|y:mg?n}YjՀ n$?x ;ptkYDRDgT4?gߤ'7'Uq Dl>.Ճ[ySQU7nՃ*혓Q؇O*09`7[G7u<./.F*ÿ 6XM>5SO==aϺ!D?`:a?m) Uq|G i"mpbUfw5+v+ P`7`P7p;8R\x<9G}s=ז BѩQINt3 Uo*qRJSEHVݴ]/-y=N  `:uT2؄i ,=z)-}L)9P8pVXhVz]*`sJ/@ 9$A <z5Y_ fQ8mx^./.2=H]gP]ΤS?cyR8Oda #LhaFj.!,Xj/;>/27G{:v[Y̤j& ?_r&`YuCcŢ#M[.;cRgtB y*j-X!q &H{eY_4 g]Ӱ }3^ѷV H; ~"@ mĔ&]=<ިcI}DIjƨPH#@4n~{3cYntF>yg@/q"RaL)G`)gYөaUK,H 2) ؏]mTmU=ꢥ5/ǎIyBZ}05Zߍ8e oc DHR&--muWIDk 5RTKtu劯`;-u6~|i|;6)<驖NƔ&pOi¼IR0zcrxaX{^ךּK }(B!+ܬT%~lo iwk9ysBGw3yeւ(Jk13&P}l#)nLLi;~ecٜP߲xa 븈pj_s5t=LFZPxn}1hjD7u&~@X 9W|y֎c<"@u")kX6RZ2)ƴՌ`1M\j_+ʋf!=Ĺ]v19=4 xݩH@UeoOY57{#/{3 g'Р:\#Y¦`sL)(< %9Vc[\umtr&PWB30tV}*ahISup<O^4 n?g/ܩg(*k^􉋉 )r3mscgO ]=-t u u;7s,: 'zÝ$Vx[`:MV9!0 ;(.C34Ugs]ahhzZiJudED* @ v9Qui GC7uyevHipV/1*g8k9Lj+1MKet|Mxj[gH (+a G侱`&/`a'..;ɭ+zýK9VbF|Νo!ɊSC[8E-sBck5=m 1|ő ;`0һwN&q"?qPyyOη|L;)%ϮOep ?˂+M2Eg7[Bd!2V&:xX̘ාFʖz,oxY̾kV3~ϤSHĺiOX|?DIB|¿v^I#Ƅ;ig-^zALS~.O_ k;hz1Gioܗ)B{^sj#U]5HC1IevPɏ?LyBX :/M %̥"QB?^ǙG4G=3$ 5S9XV8;NRr[@&{oO C8 LM d.~pT<϶3Vbͻ\˙yWGf4r"!Hfw҃G'RJvxEUPUh`&3l4٘?\_i|tGxnιes.fBN{VQtc\xUNylB`%7E"yߛ(0Y+%da싙S{Zil94u_Oc[5-v8n"|S\zm346}(3#{"qH"@6G[D`ySymZ;iC>3o4rŗXZ ˃Ku3ubR}JPTE|2r=)M?p"+vο05 ɯWK7\^E O?(OFjY(/CόdKg_L]A6|>~Gh(8 Cs;'ϔyM}C.`JIx~ #OQtEvebZb3h{ %_H/UuaHz2 P(ȄG?eQR.XFTNkzȩGu**^4MA7hzl>=N6z3v_/<&LJg灷)+nQ9XFF!,uIENDB`move=1000;blend=1000;3GE1[7?;? T?UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU@ 5 ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj$TT*T(IP_P_ԏAU__P_ZZj#P_֨?TU_ZTQP_A֪EGRkTZ_UAP_ZZjA_j֠֠jZ/֠j KZ_QDj FERQUjQGA֫ZIR?Z֠֫A_j֠֠#P_A֨?#Z֩?ZUOZ]j֠Z֪EGRkTZ_UAP_U֠֯iZj֠֠UԏA@HBBBB!D"$@H$$D!$$$ $II! BBBB@H$$D!$$$ $$$#ZWWf#$??UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$?? @@@J.@? ߨ? ߨ? ߨ??@@@x@x@ ???333333?333333???#~j????333333? ףp= ?333333???@???333333?333333? xLigand binding site 7yYPNG  IHDRc IDATx̽w]U9{M&I&!=NТ(]EAW \X/UD/zBBCd)NeeΙsΔ$e쵞#M\| CML$$7lv߉cO'ģЍ##0M!,#IoNik{l_Þ{0r2@ )i@P[( }G6v?;P D(C^v ~O1=@z0c/IdhnDB0QcuL!8Ҵ]wƔs1Mͻ*! 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BBBB@HII @HBBBB!D"$ $ $$$$"DB! I @HBBBB!D"$@H#qWWW WfW#D0ɓ? 9ꪀbinding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??@?| @?`E?`E?`E??@@@x@x@ ???333333?333333???#~j????333333? 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ZO;M^e+ߋu<"t/K(5MX,YDqE{62F}|bePrƷU ]Y?nn@\U)Z%?xgtS^HuI{3`.2id UeK?wū™}"i"iڛ6WY kV!LW(xSOȦJfvT n.?BufP2u9 Z*ߒ}殚F" o ĥ7릏9]%㤳IC~Ht%N{ph}\6 t{h߄aطtkg6fG5s::8{Yvu9E !btId 4s/ i#0>sSxլt&hZv66aʹ͍\oy8ngP+/b^`9ҙ%iI wgCreCˍ$dߍ¤yK m{kHeU;fȱk]XB0Yӝ,a8z 4G{s?/7^|[tȮuG&xϽ dߑؤwf# ~l %Y"Y"M Uޫ|HNg1>KK}O h#]ZՄfELn+ #?Cv ɫ#\ܐR*F0@FX.͇R7{z7MCÖ ^ex iEάl(*TdpvQ~߶;kT&דgA;*`_A!,î7zQҴ a$H뮟kAx+2yPkQop!F'޴W%bשtb/4/Ǿ3=;XfFiE!I[*'/]2{ +Ro5"A/%LY(8z00J}m3&6`tj4" v(o257tEd(TiC$>Mp/"DKڭcKvYL0q%Fj*|/Npi 'nI"{{lsc$S12L-L>´r%7}&2VG(~)rFk1:[8SJ@k}]vXvOK7- aM+0+^ A}bK'djn[=Kgﵡ+׬hbűU[$!Enxak2FRPa\*jl$xҽ%K&ܹ}7bt,gů<p1нMa)- Qy8L~P˺njNA~\IDATafrAз3 #!z^WR^k6r%,mZi8mUܟu;y6$1rf2Qhzseek9 okܼq3$V^02˒߮m+:Z?09J$,;߃>DQ2_&; >M"L{`Q|IENDB`move=1000;blend=1000;3GE1i7?;? TTUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUT 7 ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j JZj#P_*DTDT(T*RUTJA֫Z*HTZ_Rj ZROUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#fWWW Wf#UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUPbinding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???>6$??z6@@ *8@?@1?@1?@1??@@@x@x@ ???333333?333333???#~j????333333? ףp= ?333333???@???333333?333333? xLigand binding site 9:PNG  IHDRc IDATxw|չ>]Ւ,.w006cL 6P ] % !BB)${ 0!Lqø۲eKjcfG]i-%>/W;s̙g @ҋ^t@/uK<6zF/%^tӋnxzmO/^EK<6zF/%^tӋnxzmO/^EK<6zF/%^tӋnxzmO/ OX" ٮwpz ވѣǝדFQuC %yx--9EqpUp:a4@Jqg[@( jЧ?7ˮXN&]3rd4]E"DAc躊P2OOc ihi'-EPb{jI8s0!0t ?uhMtZ} ?Kf0Y朼!Fw6mXR;Ҍc;zraV[ٹ!X6fP\43S,%m~F Ja^_Sǟ_qyDXrRpDxN(3zɸ]^bjh,D4" gy%-[زe{ɝwo6yG 4_3z&gTGߢ ,8C+}ˇ"iڦlkګz9Fp\ΊOwsA^NHI ґO^)+}U!b/E(q` Ic;!p KA4&n#n!jFb||ӿatKw;X;?tT֭۟gT^{-~} իٸq#h7A,V}F(mN:3WE[oJr_]8*ʆNá8k:3vLӇ$ne F$j&?h,D"3lxܮ `?4<^/mm-lwHE(1)HG|W:1-\7|6K,o; s_NJ+ cǾq|rۢ}8䯥%Yv(-8i`޵97]!-ۖd%HO-\[;FBhƨA`S;W=ѳSXDCc--UDaHԮZ&,D]}644ty;(z.0 yt#FHi3 1t'_xν|+0[x+߲}pnXSUR\P^i(.'6!yH$h0*eW}ƼSVp8y|g+O]} M6@ܽR 37 An;31tPp\{][UU򗿤7h .B^~0 e)m !p$( .-cӎ5Pɀ \_x4uMFh 6rצ C՚p:xݹ^\[1Lq}D\EIAfBg|b&Ҵ[il;1H% -O0aBM$ PSSCKK #G>vُ(J5u: ݾ};.wve?Z`ZyjZ Miװ~{SňHiq!~Zg[HaRt^7|l|h ?_<Uu:o,ڣ43NW_eڵ\zܹsQUUFD"0SNMk\5`aϩܖㄲsN~pX|9u.զ5}3L.xol۶79GL# 'd Om gvEC@e^y6XCy&Mi;fslݺ .ݻw0v7S Yf-~폃k֬P^$?FcDPR7E(DPVp"Ock5X!Lkz&;K 7!uy&?YvNfgD+{<Ʌ\s kfHcp8:=DcfjXÉD{Ə''aT SVQ'#P>^~iەWnBbl$ti={_] rup q#f1ZY Qk}"㸎2FLɾ5"ڦѓ]FS"~B\ `9]#ٝ:Q}馛s+kWZowJ]bRLӢĬ)p! EMysjjrzq| +Ņ]P2O啛74T-goSt@Psx&}R"&.8e_ү~`0Hcc#~;jjjxYfM;-04;CMWQRJ"+ZD9_29$MCDcK' ڑ'Ni*?v+I}vfxl;n JqOy $%}8묳xp݄;d{,JJJ?3w9Ye COA?!Sr¼R=+), RWoJFf~ |}̣YhCY_džo*g;rVnvć.hi# l n^ielrz_-U;uM#m\?= ,aǎ7/ZlO=i3? iQ*ZiiGբDbA`jwS6Gb(-zט .7>%]u 7E(`e܈ 0Rm(_]0szXO5@An YeT7pC4MZ8.dBCKX@]]] /o ͻ[[cٽK3!P@NJ];b-dЀa44uV9gAURpgŧ=9UodB1;o|6 pAUETI#tĖ=ӢFjd߾}\s5i?Tկcƌa5p}ƃ}4ffe:@>p3p u:mfvT||'IL$ P,Pa8.tCkyEq$p:qhwh,̊Eo$0j1 ;vHOG|n7_;?_kWlbI^gjLANV^NT-ƻS2`.eқiJJ 7 ;３7-u`-Y'yw=wl$uo4RPP3{(/Mʕ,AJbĊ fwKِiWSQ)AG&3a,Vyƭ &0c BբD{,sꭨN/&0Cg[oGfψ[˻5u{-F xOgq^_Vl/F`к-贝PkNUbuRJ[3Ts$ƴ15i&XrHuO6 h ;M9ם!v]أOCq<>h@J%$;?x'P|etglTӭ=- LNDzh,HJ.5k%!i3i3qYheeeIʾEFQI9k83!ӝ$/j"qr(fL0WZ H{zL')fBy&tV. " oZ21Wn6hz1o$k}XћG P3m馃/鲟:q5uO^>eS:lDJCӖr\ʴq6Y:J20Cxm$tJg,ky Gy& Z(-NFMFTToN`*6XCm~FlK܆[8xt!m!3EVxHzVGS!Vw88Qa^)= 'ϮWISדid-OIJwuUCǟc~ǸxyКbe5B[t ^Ȍ~Gf 9>ڜjG]IDATZ0WY#[dK<FfĠW< ;C;~:]^vם{Αs*ߒ!ݿj* Yf%m[Ν#cq:H{ O@\|qh<"3B'pRB;f|W]I)tuw7 (KšH5g!<6nh&|;a+pտ0Uij?"Pp;VL5+VaS$NYh#MBI_1 gѹeܡ8xrwū͛S]'԰J )%O?iƎ'.$ĕowߝ6Cƿ#-뾒$\uV@MT8 ȣ3w <"h:& 0aư'qRUNʼn>ZMiQ? y|ۉP_P:Œ3WWX}G@`S2Џ~_jzǐH;.h5,8mU=*p"Oc{/w_Rj1bSm0G"olƢο/JnC39YML^~=RKkKz+ᅊPE GvŠb ZL)DiD4=U1 eڸٴsMJlqkl?E2f.mo`Z;)3Hp:o@tiq֌Hi'ETT=RG>OR5@:&0bcG*vTIB6rx }Tv]*F b-% Cz '4V'e^YЬGbb؀ vlxbƏϠO>!((4əӗiQuߤ-`PiUuݿP8.\YFӓS\8!:NyjwriWg4]v NҜR` n+CA (MMaZ܅Uā4# 8T|+H%ém~_Ν:b ELqo{WmbhqU:Bd!30u#R$\L񆡣 jᬫgkOjoh%s]C[S5oQhws/3 ѥǝųEHhķGکhD<4Cef\#phZZaT+ҁ3fۓ*EG ]c5l۷2޻8i\Y@h>ξ&e[QfMnR`4t]E׵aHkUB%8e}gt( mW<q!٘j>tcjqM@Z%U-ϝ˳n== s^}=I n2V>{R -q8\xpsY-ͰvM3]xa@7lD;7`i!f5&˗1.^aq# ֬uHR#LQLBR\0Ȝ:oEU#RaҜ`ngQ pE%>hPn⑴;AmcM8SQ a~/YBAQ)`3by߶gŬsé4(;_9)02V6p'84-fҡ{|<&yT-j&oL2\N}W-5XUu`.;+qk@gUֈPPh9Sc5HMǙ7"θΊse%xkZf g7LڝX\Z;g,uL睞ZT [,y*3ʫ>#tpʟP6d*!(‘ T5Fa_V0-Έ%߱^fSaUoAg*RJ^Gy $@=M2{#^QcNp,\bZMV\붽=dm]fd״2٫ q)> S 8Vy !Ү>c:)ÉpPW–==6BD3LOCC l|6SUU ) fOI}J|qDJDzŝNGq@6l3GC?Ѐ?N^3vkz(gO5/ n?ㅬ.>Uuhh9H[PӗpʍGE( 0+!0m>p(s4ǼSV:a' a羅Tog'8viVG hXdS&Kɯ]|>/6~UzUۿirzyH`3l:B(67j5 Crdpxq8~pWéiGCK5m hSW0'A C9!0,}՟w\8/+EqN ]:#Zs#\.7Kκ**Hiqۀdᬫ8g9g]?s ,a?6n7TwE5p\>?``"8:kJG~N1m+4WVX<./#J %\Rv' 5|4[?Ϫ'gd=>1Fֶz$-s \ [t`W-g\!%DcG=ې[-tlCzg3bku${EҠ~?qNm#y86N'>ْG:/=s sʥ?=; wXȅ 4MSt#:H㰧Ű1ZIqҋ#Y丕h4B4fCq6Zދnc̞MN}s[RkYFݫn-jwRUf]WT:ڔ C0vt^> #^ʴDkI$d "'IC<##P豨 T= HBYVI,d/ CGUjE'H<3B!bBp*Kh3$/)%9\}^Q.m?nƋŧ )%&/tN ;<7A0_v\Čڴm^r8& wˆNcDc!bZ #fq?5'("r_SWX.0 p9EŽ%s\%;.Uu Sc~5&R #30]5(m^jϞ|!9Cq/Kݘu$;9H,x<εeθIYO{0zΦ]ιIZRR\8 -:(rp9=VLɫN_fiܝ8E8쉂pҐIENDB`move=1000;blend=1000;3GE1\7?;? ??T0?UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU@ 1 ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QD*UEUAZQUj*QTQP_AWTEJ֤֩Z֠Z#Z[Z'AA]oF#P_A֖ZTj#ZjU?juZj WUMj*?ZZ]iUVA_WZ[Z'AA]ojG֠ZQDj FERQUjQGAUUSZ֤֩Z֠֫A_E'AA_֪5Zj $$B!D!!! I$ $$I I$!!!!B"HHHIB"!$I I$!!!!B"HHHII I$#_WfWW#N#ꪪbinding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???ZR$??@H@55@@? ? ? ??@@@x@x@ ???333333?333333???#~j????333333? ףp= ?333333???@???333333?333333? xLigand binding site 109PNG  IHDRc IDATxw|SvWKrۀ !鐐@z o7!ɍ7&N !B 7 6ɲլ.}ʹL]i%?cΜ99yARU&:۷ɓsݏ?t K(CIX rJeL¨#GҹTZEVS2׷3GϢ8o Kyy}90|5;Yyzb{a)Z %'E0 4oģfi׿E,y;`˜xTY\T??O>? $g?,W$ wRV4|>{/x|ȒLjj<!LtCCӣii% 1bZp™_ P9LIL I2f]ȎΠǶ5{ws)}M r)q;)!?UU$=FLEGBD0Q-pW}X^%U>Zэ3Вv[>z%UUY|^.ęgc>rw)@L!?U@.7 LxxxTC׭:i`ƞƫo=^z _0<(-,g#HȒ ċ?}.,{^oc-0nxtSC0Bz+>+4OEٟJٴi .%b$j s¡'K1T?<2}9x=T7O2U'ѳ׋g]ijhFLBtupݰm8|*0uwQ{&NUٙM I M5s79U¾Wq菙4{Cnn%ȲBs[5B dIǏH̘ô\'W걌zAnv!2XIf3y p_(o'.aPKl0ntfLX$ɶ]GFC2}=Á<]t 99 9S" PYk)bwӻ?w<ѣG"D0f--g54 kĴ#pl7ڟ\Sv\Kia9/lѝţf$"ʊ&ZKrEEQZdP>zV/v8PPIuQrٵnPmLx$ IpvmCjc xcȲL87ƆOq-mTlg\4 #,+tt6_Oix$9oJv۔`+1X#!u0}bKpdYV%p ^O&5 @xjTUssFqh$ɀ_~)sgtt58%75;}uACQFOFB&sŬK$*9;)FU̟q.ezlQܩ3n+FV,\vg_ 7,3&iޯ箿*W_nOIDckUӆ]4u[=X~`؛U"^cm_F5UێDYVY6Cl/(2T0Ph`S#LH;ҸFQg=ZRYA&9`ג_xozu1 _NԴv>)LZ>PT$h.f=v#ّ-@}s%@δ<Ѳ$#Ed*yO8߾/[oۀyՌI\V83D@+uo>±k4=P{gǁWٲr{HB |_WYnEHjb*kvl#Dg/>"tXָ- v} Sl&#=doG}6h(J/7~ >|ޗyK+o=[bGy}cwB`aU.ɭ߷nhF̌λ>yA >bS?B{W#cekkl92k4hn! 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Rp$ ߡG%//7bŊakDA^?]2Y̚TL7OL?_LpZP}6|>qɈ^cժU 'M:<-m{d/L; ~ƎvHS׆f-Upڔ#N[~Bʼn@# Ǜ+ieŮggW4qU_-INmPkkw<{J:m piECNὍchV MB4"EF(„3 fOJ:Cmw6tq6ND\uzvYP'1GU@B7бFV+ NJ CUdt`EQA= .f Ag'U)H*$cһ:pIe[4q)꽡0д{} &Hy$PH4D4FUHH)!jWo(XTrU+} !IxΘsY(^ Xm;"%C™ UH R57R7rQ$1e$876BHQœP/{kڐ@ӢDba38cevm A3+`Sna`ț2,OXwWx;F򳋑e9-~Sф` V Baa؅ԚYh"n ӭ֓edY&×sJF*9r6t.+)-,GQYܼ-!>I#b¢DfW YJDEU2|9#҇2TL7@+,`U,I6;$8vQ^(*sdoEzoO/11Mꦃ:L\hY^ YUvTYV;lV_~z\>ڪqaSlOZ*t]%f?!?XC)VK(-kVtzeFB:5 =M~4HS#Аp XNJ8XE0wN**4‘.eS4Tc: ZtډƂxՌS4 J݄,+(Ft-qIAN2(IENDB`move=1000;blend=1000;3GE1X7?;? ?Ts 3 ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/*TRRT(IP_P_[QH*UUAUZ֗TQZjQDkTTU_ZTQP_A֪EGRkT/j֠/P_kWZ//HP_(AH֨5O֪*US֪?Z/֠jkQQԚ#֗UkP_/Z֨?Z//F#P_A$$D!$$$ $$$ $ $$$$"DB! I @HBBBB!D"$ $ $$$$"DB! I I$ $#YWfW#??UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUbinding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??@1@OeH@<@?;ק?;ק?;ק??@@@x@x@ ???333333?333333???#~j????333333? 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BBBB@H$$D!$$$ $$$#pWW WWfW#dD FDbyUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUbinding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??%@@K@@@? 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I @HBBBB!D"$ $ $$$$"DB! I I$ $#fWWW Wf#?I??UT binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13G25[2Ey =Ey @   j/H_֨PPZT?QZ RkT֗UkQQZ֟!'uQ+_jU_Zj/!jUjZUT!Q_j*Ԛ!KZ֢WR֨PTUDWWU_j/U_Z֩ jkTT*֪_IRZZUDWuQUDWj/+?֨PCZB'U U?_꺨5CKZ"QTEUDW_$ @A$I$I@$ $ $I H H I H$1H $"YtpcU,B fI$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$IHDDDDDDDDH $ImmlmBII$"I$``ldKmmmDDE dmI"$"mH@! DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT֪?j /_U5jMjKZ/j OUR?/ZRTkR?A]ikK(AH֨5O֪*US֪?Z/֠UT֢5G֗UkP_/ZR֤j /G֠ZkTQ'UW֪UTP__U5jMjKZ/j j?TQRjZ/֠HIHHHD"B@HIB"!$I I$!!!!B"HHHIB"!$$@#, fUVUjUZFUUUjW_iUaUUjUZUZUUZjVUDDGZVUVUjUZFUUUjW_ZXDDjUZVUVUVZUQVUUZUUj_UVU_ꖩꪕDFUW*UUR*UUJUUU*WT*UʭW*RRUUKB#**URWWҫRR/UPVU_VUUUUUVUjVVU$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$I$@binding site for residue adp a 499ac1  79G1~binding site for residue gol a 500ac2Sg 1~binding site for residue po4 a 503ac5 1ubinding site for residue cl a 504ac6R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp b 499ac7  79G1~binding site for residue gol b 500ac8Sg 1~binding site for residue po4 b 501ac9 1ubinding site for residue cl b 502bc1R~1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp c 499bc2  8E1binding site for residue gol c 500bc3QSf  *1~binding site for residue po4 c 501bc4 1ubinding site for residue cl c 502bc5Q}1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue adp d 499bc6 47*1binding site for residue gol d 500bc7PRe  *1~binding site for residue po4 d 503cc1 1ubinding site for residue cl d 504cc2Px1met->mse selenomethionine MOD_RES::1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES  1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES@@1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1?333333?333333?333333???????@???$??*@ࣸQ@l(@?^7?^7?^7??@@@x@x@ ???333333?333333???#~j????333333? 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DDDHBDDDEmH """I$I$DDDDDIlm`$0 mH$$I$H$mm66$""!mm@DI-m$m""$m mD$$I$Hlm``!H$$I"I%memI%mll"""m$mI"$-lHB"""$!BI$DDD[m$DDD"""I$H B""""Kml2BlI$DI$I$"""I-mm6$Bm[mmI%6ȈKmml@!$$ I$I"m`  $I$"I$mMlImmmHmlH$ImBH"""B$DDDEm@"""I$I$DDDDDImm02I-lII$I$ImmmMmI" Bm$mm el$mmMmdk%~binding site for residue gol a 499ac1Sg 1ubinding site for residue na a 500ac2 1ubinding site for residue na a 501ac31vbinding site for residue po4 a 502ac4 1~binding site for residue po4 a 504ac6Rz 1vbinding site for residue po4 a 506ac81met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1~binding site for residue gol b 499ac9Sg 1ubinding site for residue na b 500bc1 1ubinding site for residue na b 502bc31vbinding site for residue po4 b 503bc4 1~binding site for residue po4 b 504bc5 1~binding site for residue po4 b 505bc6Rz 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol c 499bc8QSf  *1vbinding site for residue po4 c 500bc9 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES;;1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESAA1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1binding site for residue gol d 499cc1RTg*1}binding site for residue na d 500cc2  1vbinding site for residue po4 d 502cc4 1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES<<1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RESBB1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES1met->mse selenomethionine MOD_RES13GE1B1N/?;? ) ee j KZ_QDj GUT֪?j /UMj*?ZZ֪j ZkTj mj֟THP_j KZ_QDj GUT