-&3.6-1h/data/swissprot/ 3G0S.pdbdupa 1DHP.pdb[html] [head] [style type="text/css"] body { background-color: #FFFDF3; } a { text-decoration: none; } #tabs { border-bottom: .5em solid #801010; margin: 0; padding: 0; } #page1 #tabs li#tab1 a, #page2 #tabs li#tab2 a, #page3 #tabs li#tab3 a, .page4 li#tab4 a { padding: 0.25em 1em; border: solid; border-width: 1px; border-color: #801010; border-bottom: none; #background-color: none; color: #000; } #main { border-top :1px solid #666; clear: both; background: #FFFDF3; padding-top: 1px; padding-left:1px; padding-right:1px; padding-bottom:1px; min-width: 384px; } #contents { padding-top: 1px; padding-left:2px; padding-right:2px; padding-bottom:1px; background: #FFFDF3; min-width: 380px; } #header { position: relative; width: 100%; height: 3em; min-width: 384px; } #header ul#primary { margin: 0; padding: 0px; position: absolute; bottom: -1px; width:100%; } #header ul#primary li { display: inline; list-style: none; width:100%; } #header ul#primary a,#header ul#primary span,#header ul#primary a.current { display: block; float: left; padding:4px; margin: 1px 2px 2px 2px; text-align: center; font-family: tahoma, verdana, sans-serif; font-size: 85%; text-decoration: none; color: #333; } #header ul#primary span,#header ul#primary a.current,#header ul#primary a.current:hover { border: 1px solid #666; border-bottom: none; background: #FFF3B3; padding-bottom: 6px; margin-top: 0; } #header ul#primary a { background: #FFFAE1; border: 1px solid #AAA; border-bottom: none; } #header ul#primary a:hover { margin-top: 0; border-color: #666; background: #FFF7CD; padding-bottom: 5px; } #header ul#secondary { position: absolute; margin: 0; padding: 0; bottom: -1.4em; left: 1px; width: 50em; /* a width is required for Opera, older Mozilla browsers, and Konqueror browsers */ } #header ul#secondary li a,#header ul#secondary li span { width: auto; display: block; float: left; padding: 0 10px; margin: 0; border: none; border-right: 1px dotted #AAA; background: none; } #header ul#secondary li a { color: #06C; text-decoration: underline; } #header ul#secondary li a:hover { color: #333; background: transparent; padding: 0 10px; border: none; border-right: 1px dotted #AAA; } #header ul#secondary li a:active { color: #000; background: transparent; } #header ul#secondary li:last-child a { border: none; } [/style] [title]Annotation[/title] [/head] [body] [img src="#icm/image/album/csgid.png"] [hr] [h3]Dihydrodipicolinate Synthase From Salmonella Typhimurium Lt2[/h3] [p]J.Osipiuk, N.Maltseva, J.Stam, W.F.Anderson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases (Csgid)[/p] [h3]PDB Code: [a href="http://www.rcsb.org/pdb/explore.do?structureId=3G0S" target="blank"]3G0S[/a] [small](deposited on 28-JAN-09)[/small][/h3] [h3]Structural data[/h3] [p][!--icmscript name="1" display slide=slideshow.slides index="Asymmetric unit" --] [a name="1" href="#_"]Asymmetric unit[/a] [/p] [p][!--icmscript name="2" display slide=slideshow.slides index="Biological unit" --] [a name="2" href="#_"]Biological unit[/a] [/p] [p][!--icmscript name="3" display slide=slideshow.slides index="Bfactor residues" --] [a name="3" href="#_"]Bfactor residues[/a] [/p] [p][!--icmscript name="4" display slide=slideshow.slides index="Bfactor surface" --] [a name="4" href="#_"]B-factor distribution on the surface[/a] [/p] [p][!--icmscript name="5" display slide=slideshow.slides index="Homolog superposition" --] [a name="5" href="#_"]Homolog superposition[/a] [/p] [p][!--icmscript name="6" display slide=slideshow.slides index="Ligand binding site 1" --] [a name="6" href="#_"]Ligand binding site 1[/a] [/p] [p][!--icmscript name="7" display slide=slideshow.slides index="Ligand binding site 2" --] [a name="7" href="#_"]Ligand binding site 2[/a] [/p] [p][!--icmscript name="8" display slide=slideshow.slides index="Ligand binding site 3" --] [a name="8" href="#_"]Ligand binding site 3[/a] [/p] [p][!--icmscript name="9" display slide=slideshow.slides index="Ligand binding site 4" --] [a name="9" href="#_"]Ligand binding site 4[/a] [/p] [p][!--icmscript name="10" display slide=slideshow.slides index="Ligand binding site 5" --] [a name="10" href="#_"]Ligand binding site 5[/a] [/p] [p][!--icmscript name="11" display slide=slideshow.slides index="Ligand binding site 6" --] [a name="11" href="#_"]Ligand binding site 6[/a] [/p] [p][!--icmscript name="12" display slide=slideshow.slides index="Ligand binding site 7" --] [a name="12" href="#_"]Ligand binding site 7[/a] [/p] [p][!--icmscript name="13" display slide=slideshow.slides index="Ligand binding site 8" --] [a name="13" href="#_"]Ligand binding site 8[/a] [/p] [hr /] [small] [b]Controls:[/b] [table] [tr][td][b]rotate[/b][/td] [td]with the -mouse[/td][/tr] [tr][td][b]drag[/b][/td] [td] with the -mouse (or with -key pressed)[/td][/tr] [tr][td][b]zoom[/b][/td] [td] with the -mouse in the left zone of the window: zoom-up, unzoom-down[/td][/tr] [tr][td][b]clipping[/b][/td] [td] with the -mouse in the right zone of the window[/td][/tr] [/table] [p](TIP 1: Ribbon can be coloured by [!--icmscript name="m1" # display setting: color by secondary structure color ribbon Res(a_) ribbonColorStyle=1 --] [a name="m1" href="#_"]Secondary Structure[/a] or [!--icmscript name="m2" # display setting: color by NtoC color ribbon Res(a_) ribbonColorStyle=2 --] [a name="m2" href="#_"]NtoC[/a] or [!--icmscript name="m3" # display setting: color by molecule color ribbon molecule Res(a_) ribbonColorStyle=1 --] [a name="m3" href="#_"]Molecule[/a]) [/p] [p](TIP 2: the ribbon style can be changed to [!--icmscript name="r1" # display setting: normal ribbon ribbonStyle=1 --] [a name="r1" href="#_"]Normal[/a] or [!--icmscript name="r2" # display setting: smooth ribbon ribbonStyle = 5 --] [a name="r2" href="#_"]Smooth[/a]) [/p] [p](TIP 3: the background colour can be changed to [!--icmscript name="d1" # display setting: white background BKGR = "white" color background rgb={255,255,255} --] [a name="d1" href="#_"][/a] or [!--icmscript name="d2" # display setting: black background BKGR = "black" color background rgb={0,0,0} --] [a name="d2" href="#_"][/a]) [/p] [p](TIP 4: [!--icmscript name="4" display slide=slideshow.slides index="default" --] [a name="1" href="#_"]reset the view[/a]) [/p] [hr /] [p]Datapack created using [a href="http://www.molsoft.com/icm_pro.html" target="blank"]Molsoft ICM[/a] and [a href="http://www.molsoft.com/icm_browser.html" target="blank"]Molsoft Browser[/a] technologies (patent pending).[/p] [/small] [/body] [/html]  1DHP.pdb3G0S a_3G0SB1  1DHP3csgid.pngPNG  IHDR3 GDsRGBbKGD pHYs  tIME(/tEXtCommentCreated with GIMPW IDATxy\uugFlъц$&0#2f 8رvo`̋gy1Il !ej0l hA@;4f43˽ y}>ܞ:uN_9ν-֔Lezs2*(S)S)S)S)S)S)S)S)S)STHEϓd29TѨGLMe8}zP; 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'-Lk;Ȑ%)("+G],|S}w \'[,SFB@zJooGɸ4uV"!U'Hfa>9u!&%ֆ!wz2Jٲg LF)㎚u"MEVw&+;w%ɬ09;f9`\Sw 9pjջu K3BT|7$``uzt&`~@1!i j)z&L EE6KM^AM~x2:w ;RҬ S޹d? UuA!Nٍ4& iB#P!0T Q8PgR]1ޮ>:dNśc)`-/ Oybtqj7ֵ|L6'Q"$j^O 2}H>WFߢd2EZuf:6&j~6C%yl?Qg*V?ط9sPMoh)DiJˏ[%n_F'9dc%!TzsE>[BNh{|L_KRNPb赞(H H UUgfv ?*gl-a<U> ^M9+eWC~wٍM[os沢>  - &C1/&u,k.IDATqJ'C߱(B&? =03_Jݑ[vF؎mޡ\Bo]ӇwN0 Ě?,q)g\;Fٹ>(@#9H2B"P0ԺP}ߟcomo TGJձ(/qoph4.yInX+W4;(Lᩞ#I]_~C9%؊Wѕsk̰ji;0, [HH)Db&"riDk& h3WdhmqfЙCz {sߙ{\q3춐WTÆkdeZ !{)8sA'pˋ&,+A M;(_e6jCr(CE`D{iƿg.v+iDo3Vr̺\lßZTJ*UR3 Kk,gmފ+x:N3ʪVfF\|CH(?GxmD<6"AGF#h#ڈxmD<6"AGF#h#ڈxmD<6"AGsdIENDB`move=1000;blend=1000;3G0SB1(($ ZVk_֪_֭jֿ֪_֭jֿUjZխUUEU_)Xt|eeZVkOkVT###_֭j֟UUj֭iZ?"FFF22?#r $B"U f!!I$JI$ 5UUUTDDI%UURI$$UUUU$URJDDDI$ $""$! $DD!BUUJI%UURI$HJ$PUUURHB! I""$$$DDI$$PUU H$UA$UT""!PUUU* IUUTI$ BDDDI$DDI$! 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I""$$$DDI$$PUU H$UA$UT""!PUUU* IUUTI$ BDDDI$DDI$! 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Ҩc&+BR;c,M{%ƴZv\Wښ\Xr}-!ap,bh7ߍN :3DMK)t0s'**6~^%$wcQٛ1}l6(PԣV:(K@ةyw简$(yCjAHGDb?Z͌lG4vdot]<ʙmslNcP9IM H9( \2Z'qDŲZy:! Dk B}܋ H }j8 Dwm JPn$QLXD)9)A>䚮^H,?OWN$dQ(Ȏ3*ubkwO>%G @eI`ah6PBim-ik m6QiT3e/a81}ɂW]4 ւXm dÇDŽE_$=ѓ98nެNT!<^%'GCDP*B \ᵽϦ'ƙG9Tj'stغF_yy$Y"C|ԝ6`!2BIQx)G)!RMD, _T!5uP!k3(yuvCy^A(H΍RJOp͖/ohQPd?v nEe䊱d2筱,(4֥!nN!UK7E[%X:1۳4FEUƘ3niZ4ǧ@E5''']@eGQxF/b؟+pIDAT۴ P$^%77@%HlvܭW)W6-MR ﭅GAr)SZ<6sB"$уAZo';t5/8 ش4-(Hy[_|[&T{Wⱙ IR#ΚG+] R<@BFHil}UӞV<6 "hD(jƢ0^1U}+M8 'MO1YtU[C]t-x`8c Dh aIU4UgZ|4=வ !XjstG86x9.X_l^3-Z C=韌j2V'H/| aA%|.ut{屙 E6؈`#HBBpAfެNDDM5x븗 B#x< U*~{Czj Rw@%#US V<6-wڧ<VL@%+Hl[CcҴ=!5*AxdDAt4JH$#zxҘ=sbGz@wH"mYRFŒydӜ^."NU<0݉A"~Ȳ YIBRap'x `V|H%K@xM$Ǐ:µ-?UAsX~o>O DQ$ȐD'hQxIENDB`move=1000;blend=1000;3G0SB1G ((Xt|eeZVkOkVT###_֭j֟UUj֭iZ?"FFF22?#r $B"U f!!I$JI$ 5UUUTDDI%UURI$$UUUU$URJDDDI$ $""$! $DD!BUUJI%UURI$HJ$PUUURHB! I""$$$DDI$$PUU H$UA$UT""!PUUU* IUUTI$ BDDDI$DDI$! 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HHOWW WWf#'_ ubinding site for residue cl a 403ac21ubinding site for residue cl a 405ac3h1}binding site for residue cl b 404ac6 1ubinding site for residue cl b 406ac7g11DHPqvv okU?jVSZ fUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU!$I$"!B"@I$I$DD!B""$I$DDDD!B""""I$I$B"I"""I$DD!BDDBD"!B I$I$DI$I$I"""I$DDDDDDDDDI$H lpyruvate binding residue.s11tbinding site for residue k a 293ac11tbinding site for residue k b 293ac21?333333?333333?333333???????@???CumC$??׋DK? ,?@?ú?ú?ú??@@@x@x@ ???333333?333333???#~j????333333? ףp= ?333333???@???333333?333333? xLigand binding site 4$PNG  IHDRc IDATxwuϷLپ݄! 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@@@?AAA0@@?AAA0@@?AA@@?AAA0@@?AAA APA@@?AAA AP@@@?AA@@?AA@@?A@@?AAA @@@?AAA A0A@@@?AA@@?AAA APA@@?AA@@?AAA @@A@A`@@@?AAA AP@@@@?AAA0@@?AAA APA@@@?AAAA A APAP@@@@?AAA A0A@@@?AA@@?AA@@?AAA @@@@?AAAA A @@@@?AAA A0A@A`ApA@@?AAA0@@?AAA A0A@@@?AAA A0A@@@?AA@@?A@@?AAA @@@?AAA @@@?AA@@?AA@@?AA@@?AAA A0A@@@?AAA @@@?AAA A0A@A`ApA@@?AAA A@@?AAA AP@@@@?AAA A0A@@@?A@@?A@@?AAA @@A@A`@@@?A@@?AA@@?AAA0@@?AA@@?AA@@?AA@@?AA@@?AAA @@@?AA@@?AA@@?AA@@@?AAAA A APAPAA@@?AAA AP@@@?AAA A@@?AA@@?AAA @@@?AAA A@@?AA@@?AAA APA@@?AAA A0A@@@?AA@@?AA@@?AAA AP@@@?A@@?AAA AP@@@@?AAA A0A@A`ApA@@?AA@@?AAA AP@@@?AA@@?AAA APA@@?AA@@?AAA0@@?AAA @@@?AAA AP@@@@@?AAAA A APAPAA@@?AAA A0A@@@?AAA A@@?AAA AP@@?AAA A0A@@@?AAA @@A@A`@@@?AAA @@@?AAA APA@@?AAA A0A@@@?AAA A0A@A`ApA@@?AA@@?AAA AP@@@?AAA AP@@?AAA @@@?AAA AP@@?AAA0@@?AAA AP@@?AA@@?AAA APA@@?AAA A0A@ApAAAA@@?AA@@?AA@@?AAA APA@@?AA@@?AAA A0A@@@?A@@?AAA A0A@@@?AA@@?AA@@?AA@@?AAA @@@?AA@@?AAA A0A@@@?AAA APA@@?AAA A0A@@@?AAA AP@@@?AAAA A AA@@?AA@@?AAA AP@@?AAA0@@?AA@@?AAA @@@?AAA @@A@A`@@@?A@@?AAA APA@@?AAA @@@?AAA0@@?AA@@?AAA APA@@?AA@@?AA@@?AAA A0A@@@?AAA AP@@@@?AAA @@A@A`@@@?AA@@?A@@?AAA A0A@@@?AAA A0A@@@?AAA @@@?AA@@@?AAAA A AA@@?AAA A0A@A`ApA@@?AA@@?A@@?AA@@?AAA0@@?AA@@?AA@@?AAA A0A@@@?AA@@?AA@@?AAA AP@@?AAA A@@?AAA @@@@?AAAA A APAP@@@@?AAA APA@@?A@@?AAA @@@?AA@@?AA@@@?AAAA A APAPAA@@?AA@@?AA@@?AAA A0A@@@?AAA APA@@?AAA APA@@?AAA A0A@@@?AAA0@@?AAA @@@?AAA A0A@A`ApA@@?AAA @@A@A`@@@?AA@@?AA@@?AAA @@@?A@@?AA@@?AA@@?AA@@?AAA0@@?AA@@?AA@@?AA@@?A@@?AA@@?AA@@?A@@?AAA AP@@@?AA@@?AA@@?AA@@?AAA A0A@@@?AA@@?AAA @@A@A`@@@?AAA @@@?AAA AP@@@?AAA @@A@A`@@@?A@@?AAA @@@?AA@@?AA@@?AAA A@@?AAA A@@?AA@@?AAA A0A@@@?AAA AP@@@?AAA A0A@@@?AA@@?AAA @@@?A@@?AAA APA@@?AAA0@@?AAA AP@@?AA@@?AAA0@@?AA@@?A@@?AA@@?A@@?AA@@?AAA @@@?AA@@?AA@@?AA@@?AAA AP@@@?AA@@?AAA0@@?AA@@?AAA A0A@@@?AA@@?AAA AP@@@@?AAA APA@@?AAA A0A@A`ApA@@?AAA @@@?AAA @@@?AA@@?A@@@?AAAA0A0@@?AA@@?A@@?AA@@?AAA A0A@@@?AA@@?AA@@?AA@@?AAA AP@@?AAA A0A@A`ApA@@?AAA A0A@A`ApA@@?AAA @@@?AAA APA@@?AAA AP@@?AA@@?AAA AP@@@@?AAA AP@@@?A@@?AAA A0A@@@?AAA A0A@A`ApA@@?AAA AP@@@@?AAA @@A@A`@@@?AAA A0A@A`ApA@@?AAA APA@@?AA@@?AAA0@@?AA@@?AAA AP@@@?AAA @@A@A`@@@?AA@@?AAA @@@?AAA A0A@@@?AAA AP@@?AAA AP@@@@?AAA0@@?AAA A0A@@@?AAA A0A@A`ApA@@?AAA @@@?AA@@?AAA AP@@?AA@@?AAA APA@@?AA@@?A@@?AA@@?AAA @@@@?AAAA A AA@@?AAA A0A@@@?AAA AP@@@?AAAA A APAP@@@@?AA@@?AA@@?A@@?AAA APA@@?AAA A0A@@@?AA@@?AAA AP@@@?AAA0@@@?AAAA A APAPAA@@?AAA @@@?AAA0@@?AAA0@@?AA@@?AAA0@@?AAA APA@@?AAA AP@@@?AA@@?AA@@?A@@?AAA @@@?AAA A0A@@@?AA@@?AAA APA@@?AA@@?AAA @@A@A`@@@?AAA AP@@@@?AAA0@@?AAA APA@@@?AAAA A APAP@@@@?AAA A0A@@@?AA@@?AA@@@?AAAA A @@@@@@??AAAAA A @@@@?AAA A0A@A`ApA@@?AAA0@@?AAA A0A@@@?AAA A0A@@@?AA@@?A@@?AAA @@@?AAA @@@?AA@@?AA@@?AA@@?AAA A0A@@@?AAA @@@?AAA A0A@A`ApA@@?AAA A@@?AAA AP@@@@?AAA A0A@@@?A@@?A@@?AAA @@A@A`@@@?A@@?AA@@?AAA0@@?AA@@?AA@@?AA@@?AA@@?AAA @@@?AA@@?AA@@?AA@@@@??AAAAA A APAPAA@@?AAA AP@@@?AAA A@@?AA@@?AAA @@@?AAA A@@?AA@@?AAA APA@@?AAA A0A@@@?AA@@?AA@@?AAA AP@@@?A@@?AAA AP@@@@?AAA A0A@A`ApA@@?AA@@?AAA AP@@@?AA@@?AAA APA@@?AA@@?AAA0@@?AAA @@@@?AAAA A APAP@@@@@@@?AAAA A APAPAA@@?AAA A0A@@@?AAA A@@?AAA AP@@?AAA A0A@@@?AAA @@A@A`@@@?AAA @@@?AAA APA@@?AAA A0A@@@?AAA A0A@A`ApA@@?AA@@?AAA AP@@@?AAA AP@@?AAA @@@?AAA AP@@?AAA0@@?AAA AP@@?AA@@?AAA APA@@?AAA A0A@ApAAAA@@?AA@@?AA@@?AAA APA@@?AA@@?AAA A0A@@@?A@@?AAA A0A@@@?AA@@?AA@@?AA@@?AAA @@@?AA@@?AAA A0A@@@?AAA APA@@?AAA A0A@@@?AAA AP@@@?AAAA A AA@@?AA@@?AAA AP@@?AAA0@@?AA@@?AAA @@@?AAA @@A@A`@@@?A@@@?AAAA A APAPAA@@?AAA @@@?AAA0@@?AA@@?AAA APA@@?AA@@?AA@@?AAA A0A@@@?AAA AP@@@@?AAA @@A@A`@@@?AA@@?A@@?AAA A0A@@@?AAA 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1 1 1 1 1 a a a a a 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 a a a a 3 3 3 3 3 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 a a a a 5 5 5 5 5 5 5 5 5 5 5 a a a a a 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 a a a a a 7 7 7 7 7 7 8 8 8 8 8 8 8 8 8 8 a a a a a a 9 9 9 9 9 9 9 9 a a a a 10 10 10 11 11 11 11 11 11 11 11 a a a a 12 12 12 12 12 13 13 13 13 13 13 13 13 13 13 13 13 13 13 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 15 15 15 15 15 15 15 15 15 15 15 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 17 17 17 17 17 b b b b b 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 b b b b 19 19 19 19 19 19 19 19 19 20 20 20 20 20 20 20 20 20 20 20 20 20 20 20 20 20 b b b b 21 21 21 21 21 21 21 21 21 21 21 b b b b b 22 22 22 22 22 22 22 22 22 22 22 22 22 22 22 b b b b b 23 23 23 23 23 23 24 24 24 24 24 24 24 24 24 24 b b b b b b 25 25 25 25 25 25 25 25 b b b b 26 26 26 27 27 27 27 27 27 27 27 b b b b 28 28 28 28 28 29 29 29 29 29 29 29 29 29 29 29 29 29 29 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 31 31 31 31 31 31 31 31 31 31 31 32 32 32 32 32 32 32 32 32 32 32 32 32 32 320K;}?Ydihydrodipicolinate synthase; chain: a, b; synonym: dhdps; ec: 4.2.1.52; engineered: yes3G0SB13g0sC 1 2 1C'BaB?@q?ab???@ZԀu?@R: TAAMHHHMHHHWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWAAMHHHMHHHWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWT(aar f$ ffffffffffffff fffff"ffff fffffffffff fffffffffff ffffff fffffffffUf ffff BfffffffffffffffffUffffffTbb