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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90133
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_159
68449233
CD47-like putative membrane protein [Mon...
277
similar to VACV-COP-A38L, MPXV-ZAI96-A40L
Community Requests
2JJS
11.6%
Monkeypox virus
IDP90128
(
show subtarget assignments
)
8
purified
No
MPXV_ZAI1979_005_060
68449134
myristylprotein [Monkeypox virus]
166
has N-myristyltransferase target MGxxxS/T/A, similar to VACV-COP-E7R, MPXV-ZAI96...
Community Requests
Monkeypox virus
IDP90131
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_144
68449218
cowpox A-type inclusion protein [Monkeyp...
67
similar to part of CPXV-GRI-A26L
Community Requests
Monkeypox virus
IDP90132
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_155
68449229
unknown [Monkeypox virus]
176
similar to VACV-COP-A35R, MPXV-ZAI96-A37R
Community Requests
Monkeypox virus
IDP90112
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_019
68449093
unknown [Monkeypox virus]
153
similar to VACV-COP-C6L, MPXV-ZAI96-D11L
Community Requests
Monkeypox virus
IDP90127
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_045
68449119
ser/thr kinase [Monkeypox virus]
439
similar to VACV-COP-F10L, MPXV-ZAI96-C16L
Community Requests
Monkeypox virus
IDP90098
(
show subtarget assignments
)
8
purified
No
ZZZ_0014
196
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
3U66
19.4%
Escherichia coli
IDP90130
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_133
68449207
soluble myristylprotein [Monkeypox virus...
377
similar to VACV-COP-A16L, MPXV-ZAI96-A17L
Community Requests
Monkeypox virus
IDP90097
(
show subtarget assignments
)
8
cloned
No
ZZZ_0013
104
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90096
(
show subtarget assignments
)
8
expressed
No
ZZZ_0012
476
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90104
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_004
68449081
ankyrin-like protein [Monkeypox virus]
437
similar to CPXV-GRI-C1L, MPXV-ZAI96-D1L/N4R
Community Requests
2Y1L
9.6%
Monkeypox virus
IDP90111
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_017
68449091
ankyrin-like protein [Monkeypox virus]
630
similar to VACV-COP-C9L, MPXV-ZAI96-D9L
Community Requests
3NOC
5.1%
Monkeypox virus
IDP90119
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_029
68449103
ankyrin-like protein [Monkeypox virus]
442
similar to VACV-COP-M1L, MPXV-ZAI96-O1L
Community Requests
1N11
16.3%
Monkeypox virus
IDP90126
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_044
68449118
unknown [Monkeypox virus]
212
thiol substrate, similar to VACV-COP-F9L, MPXV-ZAI96-C15L
Community Requests
1YPY
21.7%
Monkeypox virus
IDP01168
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO2_0084
47566748
capsule synthesis trans-acting positive ...
483
Virulence Associated Factor
Phase 2: March 2008
3SQN
8.5%
Bacillus anthracis
IDP90007
(
show subtarget assignments
)
8
cloned
No
Z4378
12517596
qseC
quorum sensing Escherichia coli regulato...
449
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3JZ3
47%
Escherichia coli
IDP90005
(
show subtarget assignments
)
8
soluble
No
Z4377
12517595
qseB
quorum sensing Escherichia coli regulato...
219
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3Q9S
41.1%
Escherichia coli
IDP90129
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_084
68449158
myristylprotein [Monkeypox virus]
340
similar to VACV-COP-G9R, MPXV-ZAI96-G10R
Community Requests
Monkeypox virus
IDP90088
(
show subtarget assignments
)
8
soluble
No
ZZZ_0004
140
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90087
(
show subtarget assignments
)
8
cloned
No
ZZZ_0003
168
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90092
(
show subtarget assignments
)
8
purified
No
ZZZ_0008
155
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90095
(
show subtarget assignments
)
8
soluble
No
ZZZ_0011
184
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90100
(
show subtarget assignments
)
8
expressed
No
ZZZ_0016
849
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
1QVR
36.8%
Escherichia coli
IDP90103
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_003
68449080
ankyrin-like protein [Monkeypox virus]
587
similar to VACV-COP-B25R/C19L, MPXV-ZAI96-J3L/J1R
Community Requests
Monkeypox virus
IDP90107
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_012
68449086
interleukin-1 receptor antagonist-like p...
83
similar to VACV-COP-C10L, MPXV-ZAI96-D4L
Community Requests
Monkeypox virus
IDP90110
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_015
68449089
ankyrin-like protein [Monkeypox virus]
660
similar to CPXV-GRI-C9L,CPXV-BR-V024, MPXV-ZAI96-D7L
Community Requests
1N0Q
4.4%
Monkeypox virus
IDP90115
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_024
68449098
kelch-like protein [Monkeypox virus]
176
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
2XN4
26.1%
Monkeypox virus
IDP90118
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_028
68449102
alpha-amanitin target protein [Monkeypox...
177
similar to VACV-COP-N2L, MPXV-ZAI96-P2L
Community Requests
Monkeypox virus
IDP90122
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_032
68449106
serine protease inhibitor-likeprotein SP...
375
similar to VACV-COP-K2L, MPXV-ZAI96-C2L
Community Requests
3LW2
29.2%
Monkeypox virus
IDP90125
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_038
68449112
kelch-like protein [Monkeypox virus]
485
similar to VACV-COP-F3L, MPXV-ZAI96-C9L
Community Requests
1ZGK
13.6%
Monkeypox virus
IDP00223
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO3054
16123231
-
putative carboxypeptidase
225
Virulence
Phase 1: October 2007
Yersinia pestis
IDP00341
(
show subtarget assignments
)
1
cloned
No
FTT1305c
56708363
murA
UDP-N-acetylglucosamine 1-carboxyvinyltr...
444
Drug Target Function
Phase 2: March 2008
3SG1
32.7%
Francisella tularensis
IDP01167
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO2_0060
47566729
capsule synthesis trans-acting positive ...
482
Virulence Associated Factor
Phase 2: March 2008
3SQN
22%
Bacillus anthracis
IDP01166
(
show subtarget assignments
)
1
cloned
No
GBAA_pXO1_0190
47566502
hypothetical protein GBAA_pXO1_0190
410
Virulence Associated Factor
Phase 2: March 2008
Bacillus anthracis
IDP01519
(
show subtarget assignments
)
1
purified
No
VC2149
15642148
hypothetical protein VC2149
95
Drug Target Function
Phase 2: March 2008
3KE2
43.2%
Vibrio cholerae
IDP01174
(
show subtarget assignments
)
1
expressed
No
BA_2823
30257425
hypothetical protein BA_2823
375
Drug Target Function
Phase 2: March 2008
Bacillus anthracis
IDP90003
(
show subtarget assignments
)
8
crystallized
No
FTT1103
56708183
conserved hypothetical lipoprotein
365
(Community Request)
Community Requests
3GYK
12.3%
Francisella tularensis
IDP90001
(
show subtarget assignments
)
8
cloned
No
FTT0094c
56603762
qseC
sensor histidine kinase
475
Drug Target (Community Request)
Community Requests
3A0R
15.8%
Francisella tularensis
IDP90084
(
show subtarget assignments
)
8
soluble
No
ZP_01795673
145640079
hypothetical protein CGSHiII_00674 [Haem...
148
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
28.4%
Haemophilus influenzae
IDP90083
(
show subtarget assignments
)
8
cloned
No
ZP_01795671
145640077
hypothetical protein CGSHiII_00664 [Haem...
219
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
35.6%
Haemophilus influenzae
IDP90086
(
show subtarget assignments
)
8
expressed
No
ZZZ_0002
492
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP00253
(
show subtarget assignments
)
1
in_crystallization_trials
No
YFVgp1
9627245
Yellow fever virus Envelope protein
399
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1P58
43.8%
Yellow fever
IDP90090
(
show subtarget assignments
)
8
expressed
No
ZZZ_0006
310
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90091
(
show subtarget assignments
)
8
expressed
No
ZZZ_0007
660
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
2P5Z
15.6%
Escherichia coli
IDP90093
(
show subtarget assignments
)
8
expressed
No
ZZZ_0009
99
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90094
(
show subtarget assignments
)
8
cloned
No
ZZZ_0010
358
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP01101
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO1_0119
47566439
hypothetical protein GBAA_pXO1_0119
82
Virulence Associated Factor
Phase 2: March 2008
3SIK
52.4%
Bacillus anthracis
IDP90099
(
show subtarget assignments
)
8
cloned
No
ZZZ_0015
1137
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90101
(
show subtarget assignments
)
8
in_crystallization_trials
No
STM2287
16765614
sseL
deubiquitinase [Salmonella typhimurium L...
317
SseL, is a ubiquitin isopeptidase that plays a critical role in the virulence an...
Community Requests
Salmonella enterica
IDP90102
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_002
68449079
TNF-alpha-receptor-like protein [Monkeyp...
348
similar to VACV-COP-C22L/B28R, MPXV-ZAI96-J2L/J2R
Community Requests
3ON9
23.6%
Monkeypox virus
IDP90105
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_008
68449082
unknown [Monkeypox virus]
56
similar to part of CPXV-GRI-C3L
Community Requests
Monkeypox virus
IDP90106
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_011
68449085
secreted epidermal growth factor-like pr...
142
similar to VACV-COP-C11R, MPXV-ZAI96-D3R
Community Requests
1K36
16.2%
Monkeypox virus
IDP90108
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_013
68449087
bifunctional zinc finger-like protein/E3...
242
similar to VARV BEN68-zinc finger-like protein
Community Requests
2ECW
8.3%
Monkeypox virus
IDP90109
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_014
68449088
interleukin-18-binding protein [Monkeypo...
126
similar to VACWR-C12L,VARV-BSH75_banu-D7L, MPXV-ZAI96-D6L
Community Requests
3F62
79.4%
Monkeypox virus
IDP90113
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_021
68449095
unknown [Monkeypox virus]
315
similar to VACV-COP-C4L, MPXV-ZAI96-D13L
Community Requests
Monkeypox virus
IDP90114
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_023
68449097
kelch-like protein [Monkeypox virus]
105
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
Monkeypox virus
IDP90116
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_025
68449099
kelch-like protein [Monkeypox virus]
107
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
3HVE
21.5%
Monkeypox virus
IDP90117
(
show subtarget assignments
)
8
in_crystallization_trials
No
MPXV_ZAI1979_005_027
68449101
virokine protein [Monkeypox virus]
117
similar to VACV-COP-N1L, MPXV-ZAI96-P1L
Community Requests
2I39
89.7%
Monkeypox virus
IDP90120
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_030
68449104
unknown [Monkeypox virus]
220
similar to VACV-COP-M2L, MPXV-ZAI96-O2L
Community Requests
Monkeypox virus
IDP90121
(
show subtarget assignments
)
8
purified
No
MPXV_ZAI1979_005_031
68449105
ankyrin-like protein [Monkeypox virus]
284
similar to VACV-COP-K1L, MPXV-ZAI96-C1L
Community Requests
3KEA
94.7%
Monkeypox virus
IDP90123
(
show subtarget assignments
)
8
in_crystallization_trials
No
MPXV_ZAI1979_005_035
68449109
B15R-like protein [Monkeypox virus]
149
similar to VACV-COP-K7R, MPXV-ZAI96-C6R
Community Requests
2K36
94%
Monkeypox virus
IDP90124
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_036
68449110
unknown [Monkeypox virus]
219
mitochondrial-associated inhibitor of apoptosis, similar to VACV-COP-F1L, MPXV-Z...
Community Requests
2VTY
69.4%
Monkeypox virus
IDP00002
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO1_0079
47566400
-
surface layer protein, (pxo1-54)
404
Drug Target Homolog
Phase 1: October 2007
3PYW
14.4%
Bacillus anthracis
IDP00197
(
show subtarget assignments
)
1
purified
No
YPO1233
16121519
-
putative prophage repressor protein
240
Similar to Essential SALTY
Phase 1: October 2007
3BDN
46.2%
Yersinia pestis
IDP00175
(
show subtarget assignments
)
1
soluble
No
YPO1471
16121746
-
putative ATPase subunit of ATP-dependent...
880
Virulence
Phase 1: October 2007
1QVR
36.9%
Yersinia pestis
IDP00276
(
show subtarget assignments
)
1
soluble
No
AAA99437_115-280
323469
N/A
Premembrane/Membrane protein (prM)
166
Very hydrophilic; 6 Cys residues form intramolecular disulfide bonds
Phase 3: June 2008
3C5X
56%
Dengue virus
N/A
IDP00339
(
show subtarget assignments
)
1
expressed
No
FTT0711
56707830
ispD
2-C-methyl-D-erythritol 4-phosphate cyti...
229
Drug Target Function
Phase 2: March 2008
1H3M
37.1%
Francisella tularensis
IDP01109
(
show subtarget assignments
)
1
soluble
No
GBAA_pXO1_0148
47566460
hypothetical protein GBAA_pXO1_0148
150
Virulence Associated Factor
Phase 2: March 2008
3PMD
100%
Bacillus anthracis
IDP00196
(
show subtarget assignments
)
1
cloned
No
YPO1051
16121351
-
putative membrane protein
451
Virulence
Phase 1: October 2007
2ZPL
13.5%
Yersinia pestis
IDP00183
(
show subtarget assignments
)
1
cloned
No
YPO0613
16120939
-
putative permease protein
293
Virulence
Phase 1: October 2007
2R6G
22.5%
Yersinia pestis
IDP00205
(
show subtarget assignments
)
1
cloned
No
YPO1705
16121965
-
tail-specific protease precursor
690
Drug target motif; Conserved; Proteomics evidence (Cytoplasmid or periplasmic); ...
Phase 1: October 2007
1FC6
15.8%
Yersinia pestis
IDP00198
(
show subtarget assignments
)
1
cloned
No
YPO1367
16121647
-
conserved hypothetical protein
106
Similar to Essential SALTY
Phase 1: October 2007
1MBU
84.9%
Yersinia pestis
IDP00222
(
show subtarget assignments
)
1
cloned
No
YPO3049
16123226
-
putative binding protein-dependent trans...
589
Virulence
Phase 1: October 2007
3DKN
15.3%
Yersinia pestis
IDP01169
(
show subtarget assignments
)
1
cloned
No
GBAA_pXO1_0146
47566458
atxA
transcriptional activator atxa, (pxo1-11...
475
Virulence Associated Factor
Phase 2: March 2008
3SQN
20.4%
Bacillus anthracis
IDP01531
(
show subtarget assignments
)
1
in_pdb
3EFB
No
SF4094
56384059
sorC
probable sor-operon regulator [Shigella ...
315
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 3: June 2008
2W48
86.3%
Shigella flexneri
IDP01530
(
show subtarget assignments
)
1
in_pdb
3EFV
3ETF
No
STM1524
16764869
yneI
putative succinate-semialdehyde dehydrog...
462
It is an essential gene in Salmonella which is important in energy metabolism.
Phase 3: June 2008
3EFV
100%
Salmonella enterica
IDP01540
(
show subtarget assignments
)
1
in_pdb
3EC6
No
GBAA0418
47525694
general stress protein 26 [Bacillus anth...
138
CONSERVED
Phase 3: June 2008
3EC6
100%
Bacillus anthracis
IDP90000
(
show subtarget assignments
)
8
cloned
No
FTT1352
56708408
hypothetical protein FTT1352
383
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Francisella tularensis
IDP00272
(
show subtarget assignments
)
1
in_pdb
3EGP
3IRC
No
AF180817_281-775
7329982
N/A
Envelope (E)
495
Contains receptor binding sites and fusogenic domain; also contains 12 Cys resid...
Phase 1: October 2007
3G7T
78.8%
Dengue virus
N/A
IDP00255
(
show subtarget assignments
)
1
selected
No
NP_041725:276-677
9627243
CFA
Cell fusing agent virus Envelope protein...
402
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3C5X
15.2%
Cell fusing
IDP90081
(
show subtarget assignments
)
8
cloned
No
ABD79034.1
89892477
M2
matrix protein 2 [Influenza A virus (A/U...
96
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2L0J
42.7%
Influenza A
IDP90082
(
show subtarget assignments
)
8
purified
No
P03493.2
85681917
RecName: Full=Matrix protein 2; AltName:...
109
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2KJ1
64.2%
Influenza B
IDP90085
(
show subtarget assignments
)
8
purified
No
ZZZ_0001
158
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP00254
(
show subtarget assignments
)
1
in_pdb
3P54
Yes
13272205
Japanese encephalitis virus Envelope pro...
406
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3P54
98.3%
Japanese encephalitis
IDP00251
(
show subtarget assignments
)
1
cloned
No
MVEVgp1
9633623
Murray Valley encephalitis Envelope prot...
407
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3P54
78.1%
Murray Valley
IDP00252
(
show subtarget assignments
)
1
in_crystallization_trials
No
130516
St. Louis encephalitis virus Envelope pr...
407
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
2I69
70.5%
St. Louis
IDP90089
(
show subtarget assignments
)
8
expressed
No
ZZZ_0005
600
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP00257
(
show subtarget assignments
)
1
in_crystallization_trials
No
MODVgp1
20177456
Modoc virus Envelope protein
393
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1SVB
41%
Modoc virus
IDP00256
(
show subtarget assignments
)
1
expressed
No
RBVgp1
21397175
Rio Bravo bat virus Envelope protein
395
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1URZ
43.2%
Rio Bravo
IDP00271
(
show subtarget assignments
)
1
expressed
No
AF180817_115-280
7329982
N/A
Premembrane/Membrane protein (prM)
166
Very hydrophilic; 6 Cys residues form intramolecular disulfide bonds
Phase 3: June 2008
3C5X
59.6%
Dengue virus
N/A
IDP00266
(
show subtarget assignments
)
1
cloned
No
AAX48017_114-279
61652905
N/A
Premembrane/Membrane protein (prM)
166
Very hydrophilic; 6 Cys residues form intramolecular disulfide bonds
Phase 3: June 2008
3C5X
57.2%
Dengue virus
N/A
IDP00258
(
show subtarget assignments
)
1
in_crystallization_trials
No
MMLVgp1
22550316
Montana myotis leukoencephalitis Envelop...
395
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
1URZ
43.6%
Montana myotis
IDP00259
(
show subtarget assignments
)
1
crystallized
No
CPXV018
30844336
CPXV229 CDS
OMCP protein Cowpox virus
171
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
Cowpox virus
IDP00260
(
show subtarget assignments
)
1
purified
No
AF380138
17529967
N3R
N3R [Monkeypox virus]
176
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
Monkeypox virus
IDP00003
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO1_0158
47566470
gerXC
spore germination protein xc, (pxo1-112)...
317
Drug Target Homolog
Phase 1: October 2007
Bacillus anthracis
IDP00301
(
show subtarget assignments
)
1
expressed
No
CBU_0983
291
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 2: March 2008
3NVT
10.7%
Coxiella burnetii
IDP00300
(
show subtarget assignments
)
1
cloned
No
CBU_1153
548
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 2: March 2008
1GXB
10.4%
Coxiella burnetii
IDP00280
(
show subtarget assignments
)
1
purified
No
AAX48017_51-545
604449
N/A
Envelope (E)
495
Contains receptor binding sites and fusogenic domain; also contains 12 Cys resid...
Phase 3: June 2008
3UAJ
79.2%
Dengue virus
N/A
IDP90135
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_174
68449246
kelch-like protein [Monkeypox virus]
82
similar to part of VACV-COP-A55R, MPXV-ZAI96-B1R
Community Requests
Monkeypox virus
IDP90134
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_166
68449240
Toll/IL1-receptor [TIR]-like protein [Mo...
240
similar to VACV-COP-A46R, MPXV-ZAI96-A47R
Community Requests
Monkeypox virus
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