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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP00077
(
show subtarget assignments
)
0
work_stopped
No
NTL01ST3489
16422154
yhiQ
putative SAM-dependent methyltransferase...
252
Phase 1: October 2007
2PKW
100%
Salmonella enterica
Central intermediary metabolism
Other
IDP00100
(
show subtarget assignments
)
0
work_stopped
No
NT01SF2345
30041591
cheW
positive regulator of CheA protein activ...
167
Phase 1: October 2007
2HO9
100%
Shigella flexneri
Cellular processes
Chemotaxis and motility
IDP00125
(
show subtarget assignments
)
0
work_stopped
No
NT01ST1183
16764320
lrp
leucine-responsive transcriptional regul...
164
Phase 1: October 2007
2GQQ
98.8%
Salmonella enterica
Central intermediary metabolism
Other
IDP00124
(
show subtarget assignments
)
0
work_stopped
No
NT01ST0382
16763693
ghmA
phosphoheptose isomerase
192
Phase 1: October 2007
2I22
97.4%
Salmonella enterica
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP00082
(
show subtarget assignments
)
0
work_stopped
No
NTL01ST4427
16423142
lplA
lipoate-protein ligase A
338
Phase 1: October 2007
1X2G
93.2%
Salmonella enterica
Cell envelope
Other
IDP00078
(
show subtarget assignments
)
0
work_stopped
No
NTL01ST3606
16422278
rfaF
ADP-heptose; LPS heptosyltransferase 1
348
Phase 1: October 2007
1PSW
91.7%
Salmonella enterica
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP00094
(
show subtarget assignments
)
0
work_stopped
No
NT01SF0993
30040622
lrp
regulator for leucine (or lrp) regulon a...
164
Phase 1: October 2007
2GQQ
99.4%
Shigella flexneri
Central intermediary metabolism
Other
IDP00075
(
show subtarget assignments
)
0
work_stopped
No
NTL01ST3174
16421824
yraO
putative phosphoheptose isomerase
196
Phase 1: October 2007
2YVA
98%
Salmonella enterica
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP91027
(
show subtarget assignments
)
8
expressed
No
y3600
22127474
uxaC
uronate isomerase [Yersinia pestis KIM]
477
other biological interest /
-
Community Requests
3IAC
64.4%
Yersinia pestis
IDP90994
(
show subtarget assignments
)
8
purified
No
y1355
22125254
hypothetical protein y1355 [Yersinia pes...
211
other biological interest /
-
Community Requests
Yersinia pestis
IDP91002
(
show subtarget assignments
)
8
selected
No
y1919
22125812
bifunctional UDP-glucuronic acid decarbo...
667
virulence/pathogenesis /
-
Community Requests
1Z7E
70.2%
Yersinia pestis
IDP91023
(
show subtarget assignments
)
8
cloned
No
y2980
22126857
hypothetical protein y2980 [Yersinia pes...
180
other biological interest /
-
Community Requests
Yersinia pestis
IDP91025
(
show subtarget assignments
)
8
in_crystallization_trials
No
y3037
22126914
modA
molybdate transporter periplasmic protei...
263
other biological interest /
-
Community Requests
3R26
63.9%
Yersinia pestis
IDP90988
(
show subtarget assignments
)
8
expressed
No
y1189
22125092
gltI
glutamate and aspartate transporter subu...
305
other biological interest /
-
Community Requests
2IA4
75.7%
Yersinia pestis
IDP90985
(
show subtarget assignments
)
8
expressed
No
y0964
22124871
hypothetical protein y0964 [Yersinia pes...
421
other biological interest /
-
Community Requests
3MVE
41.8%
Yersinia pestis
IDP90999
(
show subtarget assignments
)
8
cloned
No
y1744
22125639
hypothetical protein y1744 [Yersinia pes...
95
other biological interest /
-
Community Requests
1X7V
33.7%
Yersinia pestis
IDP92009
(
show subtarget assignments
)
8
selected
No
ACU65237
256260263
mutant IMP-6 metallo-beta-lactamase [syn...
246
drug resistance /
256260263: We have biochemically characterized this metallo-beta-lactamase varia...
Community Requests
1DD6
91.9%
synthetic construct
IDP92008
(
show subtarget assignments
)
8
selected
No
ACU65240
256260269
mutant IMP-1 metallo-beta-lactamase [syn...
246
drug resistance /
256260269: We have characterized this metallo-beta-lactamase variant biochemical...
Community Requests
1DD6
92.3%
synthetic construct
IDP91044
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFA0002
110556113
vanY
vanY [Enterococcus faecalis]
303
drug resistance /
A carboxypeptidase thought to be involved in breakdown of normal cell wall
Community Requests
Enterococcus faecalis
IDP91034
(
show subtarget assignments
)
8
selected
No
SDY_P055
82524461
ospC1
OspC1 [Shigella dysenteriae Sd197]
470
virulence/pathogenesis /
A cell surface protein of S. dysenteriae and putative virulence factor secreted ...
Community Requests
Shigella dysenteriae
IDP91036
(
show subtarget assignments
)
8
selected
No
SDY_P151
82524557
ospC3
OspC3 [Shigella dysenteriae Sd197]
484
virulence/pathogenesis /
A cell surface protein of S. dysenteriae and putative virulence factor secreted ...
Community Requests
Shigella dysenteriae
IDP91035
(
show subtarget assignments
)
8
selected
No
SDY_P070
82524476
ospC2
OspC2 [Shigella dysenteriae Sd197]
484
virulence/pathogenesis /
A cell surface protein of S. dysenteriae and putative virulence factor secreted ...
Community Requests
Shigella dysenteriae
IDP91874
(
show subtarget assignments
)
8
cloned
No
SA0006
15925711
gyrA
DNA gyrase subunit A [Staphylococcus aur...
889
drug target /
Achillion Pharmaceuticals is interested in obtaining crystal structural data by ...
Community Requests
2XCO
55.1%
Staphylococcus aureus
IDP91876
(
show subtarget assignments
)
8
purified
No
HMPREF0023_2561
226953731
ftsI
septum formation, penicillin binding pro...
609
Acinetobacter spp. are increasingly problematic pathogens in United States hospi...
Community Requests
3UE3
89.7%
Acinetobacter sp.
IDP91642
(
show subtarget assignments
)
8
cloned
No
NP_216895
15609516
peptide synthetase MBTF (peptide synthas...
1461
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2VSQ
20.2%
Mycobacterium tuberculosis
IDP91645
(
show subtarget assignments
)
8
soluble
No
NP_215862
15608486
acyl-CoA dehydrogenase [Mycobacterium tu...
386
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
1WS9
27.2%
Mycobacterium tuberculosis
IDP91643
(
show subtarget assignments
)
8
cloned
No
NP_215860
15608484
acyl carrier protein [Mycobacterium tube...
106
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
4DXE
19.8%
Mycobacterium tuberculosis
IDP91644
(
show subtarget assignments
)
8
purified
No
NP_215861
15608485
long-chain-fatty-acid--[acyl-carrier-pro...
521
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
3PBK
31.5%
Mycobacterium tuberculosis
IDP91651
(
show subtarget assignments
)
8
cloned
No
NP_216894
15609515
lysine-N-oxygenase MBTG (L-lysine 6-mono...
431
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
Mycobacterium tuberculosis
IDP91640
(
show subtarget assignments
)
8
cloned
No
NP_216900
15609521
bifunctional salicyl-AMP ligase/salicyl-...
565
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
1MD9
42.1%
Mycobacterium tuberculosis
IDP91650
(
show subtarget assignments
)
8
cloned
No
NP_216898
15609519
polyketide synthetase MBTC (polyketide s...
444
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2QO3
47.1%
Mycobacterium tuberculosis
IDP91639
(
show subtarget assignments
)
8
cloned
No
NP_216896
15609517
peptide synthetase MBTE (peptide synthas...
1682
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2VSQ
17.7%
Mycobacterium tuberculosis
IDP91641
(
show subtarget assignments
)
8
cloned
No
NP_216899
15609520
phenyloxazoline synthase MBTB (phenyloxa...
1414
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2VSQ
23.6%
Mycobacterium tuberculosis
IDP91638
(
show subtarget assignments
)
8
expressed
No
NP_216897
15609518
polyketide synthetase MBTD (polyketide s...
1004
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2HG4
15.5%
Mycobacterium tuberculosis
IDP91019
(
show subtarget assignments
)
8
selected
No
y2821
22126698
poxB
pyruvate dehydrogenase [Yersinia pestis ...
573
potential drug target /
alternative pathway for aerobic energy metabolism
Community Requests
3EY9
79.2%
Yersinia pestis
IDP91783
(
show subtarget assignments
)
8
in_pdb
4EBK
4EBJ
No
AAM76670
30171089
ant4'-IIb
aminoglycoside nucleotidyltransferase [P...
251
drug resistance /
Aminoglycoside nucleotidyltransferase (ant4'-IIb) gene (aminoglycoside resistanc...
Community Requests
4EBJ
98.8%
Pseudomonas aeruginosa
IDP91024
(
show subtarget assignments
)
8
cloned
No
y2983
22126860
outer membrane protein C2 [Yersinia pest...
371
drug resistance /
anion-specific outer membrane porin
Community Requests
3HW9
59.9%
Yersinia pestis
IDP90179
(
show subtarget assignments
)
8
cloned
No
AAM13473.1
20153012
CPXV025 CDS
CPXV026 protein
63
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90193
(
show subtarget assignments
)
8
cloned
No
AAM13637.1
20153176
CPXV198 CDS
CPXV198 protein
558
ankyrin-like protein
Community Requests
1N11
11.1%
Cowpox virus
conserved hypothetical proteins
0
IDP90180
(
show subtarget assignments
)
8
cloned
No
AAM13474.1
20153013
CPXV027 CDS
CPXV027 protein
632
ankyrin-like protein
Community Requests
3NOC
5.4%
Cowpox virus
conserved hypothetical proteins
0
IDP90194
(
show subtarget assignments
)
8
expressed
No
AAM13639.1
20153178
CPXV200 CDS
CPXV200 protein
179
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90200
(
show subtarget assignments
)
8
purified
No
AAM13652.1
20153191
CPXV213 CDS
CPXV213 protein
800
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90203
(
show subtarget assignments
)
8
selected
No
AAM13658.1
20153197
CPXV220 CDS
CPXV220 protein
579
ankyrin-like protein
Community Requests
2FO1
10.4%
Cowpox virus
conserved hypothetical proteins
0
IDP90199
(
show subtarget assignments
)
8
cloned
No
AAM13650.1
20153189
CPXV211 CDS
CPXV211 protein
574
ankyrin-like protein
Community Requests
3F6Q
5.6%
Cowpox virus
conserved hypothetical proteins
0
IDP90178
(
show subtarget assignments
)
8
purified
No
AAM13472.1
20153011
VHR1
VHR1 or CPXV025 protein
668
ankyrin-like protein, CP77
Community Requests
1N11
10%
Cowpox virus
host range protein
0
IDP90220
(
show subtarget assignments
)
8
selected
No
MYXV_gp153
9633785
m150R
m150R
494
ankyrin-like protein, myxoma nuclear factor
Community Requests
Myxoma virus
host range factor
0
IDP90218
(
show subtarget assignments
)
8
soluble
No
MYXV_gp151
9633783
m148R
m148R
675
ankyrin motif, similar to VACV-Cop:B4R
Community Requests
2J8S
6.1%
Myxoma virus
host range factor
0
IDP90207
(
show subtarget assignments
)
8
soluble
No
MYXV_gp152
9633784
m149R
m149R
490
ankyrin motif, similar to VACV-Cop:B4R
Community Requests
1N11
14.9%
Myxoma virus
host range factor
0
IDP90216
(
show subtarget assignments
)
8
expressed
No
MYXV_gp008
9633799
m005L
m005L, m5, M-T5
483
ankyrin motif, similar to VACV-Cop:B4R. Possible apoptosis regulator.
Community Requests
1N0R
8.5%
Myxoma virus
host range factor, host defense modulator
0
IDP90174
(
show subtarget assignments
)
8
cloned
No
AAM13466.1
20153005
CPXV019 CDS
CPXV019 protein
796
ankyrin repeat protein
Community Requests
3HG0
3.8%
Cowpox virus
conserved hypothetical proteins
0
IDP90184
(
show subtarget assignments
)
8
expressed
No
AAM13486.1
20153025
CPXV039 CDS
CPXV039 protein
473
ankyrin repeat protein
Community Requests
1N11
14.4%
Cowpox virus
conserved hypothetical proteins
0
IDP90173
(
show subtarget assignments
)
8
cloned
No
AAM13464.1
20153003
CPXV017 CDS
CPXV017 protein
435
ankyrin repeat protein
Community Requests
2BKG
9.9%
Cowpox virus
conserved hypothetical proteins
0
IDP90170
(
show subtarget assignments
)
8
selected
No
AAM13458.1
20152997
CPXV011 CDS
CPXV011 protein
658
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90172
(
show subtarget assignments
)
8
cloned
No
AAM13463.1
20153002
CPXV016 CDS
CPXV016 protein
764
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90204
(
show subtarget assignments
)
8
cloned
No
AAM13452.1
20152991
CPXV006 CDS
CPXV006 protein
619
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP05773
(
show subtarget assignments
)
1
in_pdb
3OQ3
No
AAX23681
60547415
soluble interferon-alpha/beta receptor [...
358
essential/virulence/pathogenesis /
An ortholog of IDP90145 (EVM166), a monkeypox target. The description of the mou...
Phase 5: 2010
3OQ3
91.6%
Ectromelia virus
IDP91033
(
show subtarget assignments
)
8
cloned
No
SAR0023
49240405
sasH
putative 5'-nucleotidase [Staphylococcus...
786
virulence/pathogenesis /
An uncharacterized cell surface protein of staph. aureus with an anchor site for...
Community Requests
2Z1A
22.5%
Staphylococcus aureus
IDP91039
(
show subtarget assignments
)
8
selected
No
Sd1012_5151
194431100
hdeB
HdeB protein [Shigella dysenteriae 1012]...
108
potential drug target /
A protein that is important for acid resistance in some enteropathogens; it is a...
Community Requests
2XUV
65.7%
Shigella dysenteriae
IDP05006
(
show subtarget assignments
)
1
cloned
No
BA_3083
30257668
putative lipoprotein [Bacillus anthracis...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05005
(
show subtarget assignments
)
1
cloned
No
CDP11
110666933
hypothetical protein CDP11 [Clostridium ...
33
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP05007
(
show subtarget assignments
)
1
cloned
No
BA_3383
30257926
putative lipoprotein [Bacillus anthracis...
236
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05003
(
show subtarget assignments
)
1
cloned
No
BA_3309
30257855
hypothetical protein BA_3309 [Bacillus a...
31
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05004
(
show subtarget assignments
)
1
cloned
No
CDP01
110666923
hypothetical protein CDP01 [Clostridium ...
33
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP05065
(
show subtarget assignments
)
1
soluble
No
CD2469
126700086
spoIIP
putative stage II sporulation protein P ...
339
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05050
(
show subtarget assignments
)
1
purified
No
BA_5330
30259806
iron compound ABC transporter, iron comp...
333
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3GFV
26.4%
Bacillus anthracis
Transport and binding proteins: Cations and iron carrying compounds
IDP05001
(
show subtarget assignments
)
1
purified
No
BA_1090
30254820
putative lipoprotein [Bacillus anthracis...
142
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05059
(
show subtarget assignments
)
1
soluble
No
CD0690
126698269
putative nucleotide phosphodiesterase [C...
655
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3GVE
15.3%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05002
(
show subtarget assignments
)
1
cloned
No
lmo0086
16802134
-
hypothetical protein lmo0086 [Listeria m...
1959
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3TUF
2.8%
Listeria monocytogenes
IDP05009
(
show subtarget assignments
)
1
soluble
No
BA_4237
30258740
putative lipoprotein [Bacillus anthracis...
253
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05068
(
show subtarget assignments
)
1
soluble
No
CD2735
126700350
cell surface protein [Clostridium diffic...
475
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2KQ8
5.5%
Clostridium difficile
Cell envelope: Other
IDP05112
(
show subtarget assignments
)
1
cloned
No
CD2246
126699864
cspC
putative germination-specific protease [...
557
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3EIF
22.3%
Clostridium difficile
Unknown function: General
IDP05122
(
show subtarget assignments
)
1
expressed
No
BA_3551
30258083
amyS
alpha-amylase [Bacillus anthracis str. A...
513
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1VJS
68.6%
Bacillus anthracis
Energy metabolism: Biosynthesis and degradation of polysaccharides
IDP05093
(
show subtarget assignments
)
1
cloned
No
lmo0193
16802239
-
hypothetical protein lmo0193 [Listeria m...
225
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
4DK0
24.6%
Listeria monocytogenes
Hypothetical proteins: Conserved
IDP05048
(
show subtarget assignments
)
1
cloned
No
BA_4771
30259258
conserved hypothetical protein [Bacillus...
289
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP05094
(
show subtarget assignments
)
1
purified
No
BA_3160
30257733
hypothetical protein BA_3160 [Bacillus a...
257
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05046
(
show subtarget assignments
)
1
expressed
No
BA_3529
30258064
hypothetical protein BA_3529 [Bacillus a...
117
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05047
(
show subtarget assignments
)
1
soluble
No
BA_4154
30258660
ctaC
cytochrome c oxidase, subunit II [Bacill...
349
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1FFT
19.2%
Bacillus anthracis
Energy metabolism: Electron transport
IDP05049
(
show subtarget assignments
)
1
soluble
No
BA_5058
30259547
putative lipoprotein [Bacillus anthracis...
271
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05098
(
show subtarget assignments
)
1
purified
No
CD0569
126698147
putative outer membrane lipoprotein [Clo...
334
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2FQW
21.3%
Clostridium difficile
Cell envelope: Other
IDP05018
(
show subtarget assignments
)
1
purified
No
BA_2679
30257293
hypothetical protein BA_2679 [Bacillus a...
47
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05017
(
show subtarget assignments
)
1
cloned
No
BA_2521
30257145
putative lipoprotein [Bacillus anthracis...
52
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05104
(
show subtarget assignments
)
1
cloned
No
CD1233
126698829
cell surface protein [Clostridium diffic...
475
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05092
(
show subtarget assignments
)
1
cloned
No
CD1047
126698631
cell surface protein [Clostridium diffic...
350
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05095
(
show subtarget assignments
)
1
soluble
No
BA_5481
30259944
conserved domain protein [Bacillus anthr...
290
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Domain
IDP05105
(
show subtarget assignments
)
1
cloned
No
CD1374
126698975
hypothetical protein CD1374 [Clostridium...
1743
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
4D9S
5.9%
Clostridium difficile
Regulatory functions: Other
IDP05111
(
show subtarget assignments
)
1
cloned
No
CD2187
126699803
putative phage-related cell wall hydrola...
297
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3FI7
21.2%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP05114
(
show subtarget assignments
)
1
cloned
No
CD2537
126700154
putative membrane-associated 5'-nucleoti...
605
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3IVD
25.1%
Clostridium difficile
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
IDP05127
(
show subtarget assignments
)
1
soluble
No
BA_4652
30259150
putative substrate-binding family protei...
314
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3HXP
29.6%
Bacillus anthracis
Transport and binding proteins: Unknown substrate
IDP05083
(
show subtarget assignments
)
1
cloned
No
lmo2444
16804482
-
hypothetical protein lmo2444 [Listeria m...
1310
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3LPO
13.1%
Listeria monocytogenes
Central intermediary metabolism: Other
IDP05041
(
show subtarget assignments
)
1
purified
No
BA_2335
30256973
hypothetical protein BA_2335 [Bacillus a...
64
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05040
(
show subtarget assignments
)
1
expressed
No
BA_2262
30256905
heat shock protein, Hsp20 family [Bacill...
145
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1GME
30.3%
Bacillus anthracis
Cellular processes: Adaptations to atypical conditions
IDP05081
(
show subtarget assignments
)
1
expressed
No
lmo2027
16804066
-
putative cell surface protein, internali...
367
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2Y5Q
23.2%
Listeria monocytogenes
Transport and binding proteins: Amino acids, peptides and amines
IDP05086
(
show subtarget assignments
)
1
soluble
No
BA_0014
30253529
deoxynucleoside kinase family protein [B...
222
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2A2Z
29.8%
Bacillus anthracis
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
IDP05082
(
show subtarget assignments
)
1
cloned
No
lmo2179
16804218
-
peptidoglycan binding protein [Listeria ...
1152
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2KT7
2.3%
Listeria monocytogenes
Regulatory functions: Other
IDP05010
(
show subtarget assignments
)
1
soluble
No
BA_4934
30259430
putative lipoprotein [Bacillus anthracis...
144
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05076
(
show subtarget assignments
)
1
soluble
No
lmo0801
16802843
-
hypothetical protein lmo0801 [Listeria m...
646
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1M9S
22.1%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05069
(
show subtarget assignments
)
1
cloned
No
CD2789
126700405
cwp66
cell surface protein [Clostridium diffic...
610
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05045
(
show subtarget assignments
)
1
soluble
No
BA_3418
30257959
putative lipoprotein [Bacillus anthracis...
131
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05042
(
show subtarget assignments
)
1
soluble
No
BA_2921
30257513
putative sulfonate ABC transporter, sulf...
328
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2X26
28%
Bacillus anthracis
Transport and binding proteins: Anions
IDP05106
(
show subtarget assignments
)
1
cloned
No
CD1469
126699073
cell surface protein (putative penicilli...
990
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2QMI
10%
Clostridium difficile
Cell envelope: Other
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