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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP92567
(
show subtarget assignments
)
8
selected
No
AEF33500
333454592
polyprotein, partial [Dengue virus 3]
749
potential drug target /
Dengue plasmid entered for cocrystal studies with a small molecule West Nile pro...
Community Requests
2VBC
65.2%
Dengue virus
IDP92566
(
show subtarget assignments
)
8
selected
No
AAO83387
29725867
polyprotein, partial [Dengue virus 4]
263
potential drug target /
Dengue plasmid entered for cocrystal studies with a small molecule West Nile pro...
Community Requests
2VBC
67.7%
Dengue virus
IDP92565
(
show subtarget assignments
)
8
selected
No
AAA66406
807601
nonstructural protein 1, partial [Dengue...
886
potential drug target /
Dengue plasmid entered for cocrystal studies with a small molecule West Nile pro...
Community Requests
2WZQ
38.7%
Dengue virus
IDP92564
(
show subtarget assignments
)
8
selected
No
3L6P_A
290560467
Chain A, Crystal Structure Of Dengue Vir...
236
potential drug target /
Dengue plasmid entered for cocrystal studies with a small molecule West Nile pro...
Community Requests
3L6P
100%
Dengue virus
IDP92563
(
show subtarget assignments
)
8
selected
No
3E90_B
221046696
Chain B, West Nile Vi Rus Ns2b-Ns3protea...
198
potential drug target /
We have identified a number of small molecule inhibitor to West Nile and/or deng...
Community Requests
3E90
100%
West Nile
IDP92561
(
show subtarget assignments
)
8
selected
No
3EQV_A
209870568
Chain A, Crystal Structure Of Penicillin...
542
potential drug target /
Pptase, FactorXa, HCV NS3/NS4A, Trypsin and Elastase/Subtilisin (see below)] and...
Community Requests
3EQV
99.8%
Neisseria gonorrhoeae
IDP92560
(
show subtarget assignments
)
8
selected
No
1PYY_A
37927671
Chain A, Double Mutant Pbp2x T338aM339F ...
702
potential drug target /
Pptase, FactorXa, HCV NS3/NS4A, Trypsin and Elastase/Subtilisin (see below)] and...
Community Requests
1PYY
100%
Streptococcus pneumoniae
IDP92559
(
show subtarget assignments
)
8
selected
No
1MWR_A
24987837
Chain A, Structure Of Semet Penicillin B...
646
potential drug target /
Pptase, FactorXa, HCV NS3/NS4A, Trypsin and Elastase/Subtilisin (see below)] and...
Community Requests
1MWR
97.4%
Staphylococcus aureus
IDP92558
(
show subtarget assignments
)
8
selected
No
CAA87463
1065719
aadB
aminoglycoside adenylyltransferase [Esch...
177
drug resistance /
This enzyme is one of the most clinically widespread aminogylcoside-deactivating...
Community Requests
Escherichia coli
IDP92557
(
show subtarget assignments
)
8
selected
No
FTN_0757
118497352
membrane protein [Francisella novicida U...
1629
virulence/pathogenesis /
We have shown that this protein plays a role in virulence in Francisella novicid...
Community Requests
Francisella novicida
IDP92556
(
show subtarget assignments
)
8
selected
No
VV1_1076
27360618
HTH-type transcriptional regulator ilvY ...
296
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
2H99
21.6%
Vibrio vulnificus
IDP92555
(
show subtarget assignments
)
8
selected
No
VV1_0649
27360224
Long-chain-fatty-acid--CoA ligase [Vibri...
601
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
3TSY
23.6%
Vibrio vulnificus
IDP92554
(
show subtarget assignments
)
8
selected
No
VV1_1165
27360700
Glycerol-3-phosphate acyltransferase [Vi...
809
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
Vibrio vulnificus
IDP92553
(
show subtarget assignments
)
8
selected
No
VV1_2233
27361706
fadR
fatty acid metabolism transcriptional re...
279
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
1E2X
52%
Vibrio vulnificus
IDP92552
(
show subtarget assignments
)
8
selected
No
NP_071445
11545912
NOD2
nucleotide-binding oligomerization domai...
1040
innate immunity /
JUSTIFICATION:NOD2 is a cytoplasmic protein containing 1040 residus and three fu...
Community Requests
1DFJ
9%
Homo sapiens
IDP92551
(
show subtarget assignments
)
8
selected
No
YP_001527882
158516893
unnamed protein product [West Nile virus...
231
potential drug target /
This protein is interesting for several reasons. First that it may prevent prope...
Community Requests
West Nile
IDP92250
(
show subtarget assignments
)
8
selected
No
FTL_0803
89256173
hypothetical protein FTL_0803 [Francisel...
127
virulence/pathogenesis /
We recently described FTN_1133/FTL_0803/FTT_1152 as an important virulence facto...
Community Requests
Francisella tularensis
IDP92249
(
show subtarget assignments
)
8
selected
No
FTT_1152
56604715
hypothetical protein [Francisella tulare...
127
virulence/pathogenesis /
We recently described FTN_1133/FTL_0803/FTT_1152 as an important virulence facto...
Community Requests
Francisella tularensis
IDP92248
(
show subtarget assignments
)
8
selected
No
FTN_1133
118497723
hypothetical protein FTN_1133 [Francisel...
127
virulence/pathogenesis /
We recently described FTN_1133/FTL_0803/FTT_1152 as an important virulence facto...
Community Requests
Francisella novicida
IDP92247
(
show subtarget assignments
)
8
selected
No
ABA71730
77380198
vanWG
VanWG [Enterococcus faecalis]
281
drug resistance /
Community-requested targets (Patrice Courvalin, Pasteur Institute). Gene is foun...
Community Requests
Enterococcus faecalis
IDP92246
(
show subtarget assignments
)
8
selected
No
EF_2296
2499116
RecName: Full=Vancomycin B-type resistan...
275
drug resistance /
Community-requested targets (Patrice Courvalin, Pasteur Institute). Gene is foun...
Community Requests
Enterococcus faecalis
IDP92144
(
show subtarget assignments
)
8
selected
No
TGME49_110960
211962004
vacuolar ATP synthase subunit F, putativ...
127
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2QAI
22%
Toxoplasma gondii
IDP92143
(
show subtarget assignments
)
8
selected
No
TGME49_068560
237832503
RAD2 endonuclease, putative [Toxoplasma ...
2004
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1UL1
4.4%
Toxoplasma gondii
IDP92142
(
show subtarget assignments
)
8
selected
No
TGME49_112230
237830295
DNA topoisomerase II, putative [Toxoplas...
1687
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3QX3
22.5%
Toxoplasma gondii
IDP92141
(
show subtarget assignments
)
8
selected
No
TGME49_066730
237838909
leucyl-tRNA synthetase, putative [Toxopl...
1465
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1H3N
22.7%
Toxoplasma gondii
IDP92140
(
show subtarget assignments
)
8
selected
No
TGME49_072740
237833217
DNA-directed RNA polymerase III subunit,...
1332
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1I3Q
34.5%
Toxoplasma gondii
IDP92139
(
show subtarget assignments
)
8
selected
No
TGME49_058030
237831459
DNA polymerase delta catalytic subunit, ...
1268
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3IAY
28.2%
Toxoplasma gondii
IDP92138
(
show subtarget assignments
)
8
selected
No
TGME49_073450
237833297
sufB/sufD domain-containing protein [Tox...
1267
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1VH4
3.3%
Toxoplasma gondii
IDP92137
(
show subtarget assignments
)
8
selected
No
TGME49_097780
237843801
DNA gyrase subunit B, putative [Toxoplas...
1257
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3NUH
11.9%
Toxoplasma gondii
IDP92136
(
show subtarget assignments
)
8
selected
No
TGME49_112510
211962137
hypothetical protein TGME49_112510 [Toxo...
1107
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92135
(
show subtarget assignments
)
8
selected
No
TGME49_045670
211964661
pyruvate dehydrogenase, putative [Toxopl...
635
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1NI4
20.6%
Toxoplasma gondii
IDP92134
(
show subtarget assignments
)
8
selected
No
TGME49_033500
237837823
triosephosphate isomerase, putative [Tox...
375
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1MO0
36%
Toxoplasma gondii
IDP92133
(
show subtarget assignments
)
8
selected
No
TGME49_033110
211965834
inosine-5'-monophosphate dehydrogenase, ...
551
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1JCN
53.6%
Toxoplasma gondii
IDP92132
(
show subtarget assignments
)
8
selected
No
TGME49_053290
237840177
valyl-tRNA synthetase, putative [Toxopla...
1042
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1GAX
35.3%
Toxoplasma gondii
IDP92131
(
show subtarget assignments
)
8
selected
No
TGME49_019540
237842821
alanyl-tRNA synthetase, putative [Toxopl...
1037
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2ZZF
21.2%
Toxoplasma gondii
IDP92130
(
show subtarget assignments
)
8
selected
No
TGME49_061800
237832029
helicase, putative [Toxoplasma gondii ME...
1008
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92129
(
show subtarget assignments
)
8
selected
No
TGME49_007990
237840609
ftsJ-like methyltransferase domain-conta...
981
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1EIZ
6.9%
Toxoplasma gondii
IDP92128
(
show subtarget assignments
)
8
selected
No
TGME49_082200
237844257
clpB protein, putative [Toxoplasma gondi...
970
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1QVR
38.7%
Toxoplasma gondii
IDP92127
(
show subtarget assignments
)
8
selected
No
TGME49_021310
237841325
aminopeptidase N, putative [Toxoplasma g...
966
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2GTQ
33.6%
Toxoplasma gondii
IDP92126
(
show subtarget assignments
)
8
selected
No
TGME49_068650
237832521
clp ATP-binding chain B1, putative [Toxo...
929
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1QVR
48.9%
Toxoplasma gondii
IDP92125
(
show subtarget assignments
)
8
selected
No
TGME49_057990
237831451
heat shock protein, putative [Toxoplasma...
921
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1QVR
46.4%
Toxoplasma gondii
IDP92124
(
show subtarget assignments
)
8
selected
No
TGME49_110150
237829927
long-chain-fatty-acid-CoA ligase, putati...
866
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92123
(
show subtarget assignments
)
8
selected
No
TGME49_110080
237829913
long-chain-fatty-acid-CoA ligase, putati...
841
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92122
(
show subtarget assignments
)
8
selected
No
TGME49_049560
237835983
DNA-directed RNA polymerase alpha chain,...
836
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92121
(
show subtarget assignments
)
8
selected
No
ADC80547
289064343
methionyl-tRNA formyltransferase [Toxopl...
885
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1FMT
10.3%
Toxoplasma gondii
IDP92120
(
show subtarget assignments
)
8
selected
No
TGME49_073490
237833305
glutamine synthetase, putative [Toxoplas...
579
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3NG0
43.4%
Toxoplasma gondii
IDP92119
(
show subtarget assignments
)
8
selected
No
TGME49_112520
237830353
tRNA delta(2)-isopentenylpyrophosphate t...
741
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3EPH
19.2%
Toxoplasma gondii
IDP92118
(
show subtarget assignments
)
8
selected
No
TGME49_015480
237843139
adenosine/AMP deaminase domain containin...
515
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3OU8
21.7%
Toxoplasma gondii
IDP92117
(
show subtarget assignments
)
8
selected
No
TGME49_073410
237833291
tyrosyl-tRNA synthetase, putative [Toxop...
646
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1TYC
18.7%
Toxoplasma gondii
IDP92116
(
show subtarget assignments
)
8
selected
No
TGME49_060680
237831887
DNA primase small subunit, putative [Tox...
509
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1G71
9.2%
Toxoplasma gondii
IDP92115
(
show subtarget assignments
)
8
selected
No
TGME49_048850
237835867
methionine aminopeptidase, putative [Tox...
416
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3S6B
48.3%
Toxoplasma gondii
IDP92114
(
show subtarget assignments
)
8
selected
No
TGME49_011330
237843941
methionine aminopeptidase, putative [Tox...
329
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1Y1N
36.8%
Toxoplasma gondii
IDP92113
(
show subtarget assignments
)
8
selected
No
TGME49_118590
237841001
mrp protein, putative [Toxoplasma gondii...
644
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3KB1
14%
Toxoplasma gondii
IDP92112
(
show subtarget assignments
)
8
selected
No
TGME49_057730
237831419
methionine aminopeptidase, putative [Tox...
387
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2B3H
32.3%
Toxoplasma gondii
IDP92111
(
show subtarget assignments
)
8
selected
No
TGME49_015280
237843099
iron-sulfur subunit of succinate dehydro...
342
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1ZOY
45%
Toxoplasma gondii
IDP92110
(
show subtarget assignments
)
8
selected
No
TGME49_001380
237836313
chorismate synthase, putative [Toxoplasm...
536
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1R52
36.9%
Toxoplasma gondii
IDP92109
(
show subtarget assignments
)
8
selected
No
TGME49_106930
237845137
proteasome subunit beta type 7, putative...
368
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1IRU
32.6%
Toxoplasma gondii
IDP92108
(
show subtarget assignments
)
8
selected
No
TGME49_093180
237841645
NADP-specific glutamate dehydrogenase, p...
489
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2BMA
52.4%
Toxoplasma gondii
IDP92107
(
show subtarget assignments
)
8
selected
No
TGME49_091640
237838437
aspartate carbamoyltransferase [Toxoplas...
423
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1AT1
30.5%
Toxoplasma gondii
IDP92106
(
show subtarget assignments
)
8
selected
No
TGME49_079450
237845375
adenylosuccinate synthetase, putative [T...
460
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1P9B
48.7%
Toxoplasma gondii
IDP92105
(
show subtarget assignments
)
8
selected
No
TGME49_043800
237835163
long-chain fatty acid CoA ligase, putati...
748
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3NYQ
17.8%
Toxoplasma gondii
IDP92104
(
show subtarget assignments
)
8
selected
No
TGME49_026400
237833991
lipoic acid synthase [Toxoplasma gondii ...
543
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92103
(
show subtarget assignments
)
8
selected
No
TGME49_097970
237843837
aspartyl aminopeptidase, putative [Toxop...
506
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3VAR
40.7%
Toxoplasma gondii
IDP92102
(
show subtarget assignments
)
8
selected
No
TGME49_069110
237832613
ornithine aminotransferase, putative [To...
441
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1GBN
47.2%
Toxoplasma gondii
IDP92101
(
show subtarget assignments
)
8
selected
No
TGME49_032340
237837613
protein phosphatase 2C, putative [Toxopl...
546
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2I0O
17.9%
Toxoplasma gondii
IDP92100
(
show subtarget assignments
)
8
selected
No
TGME49_118430
237840969
malate dehydrogenase, putative [Toxoplas...
470
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3GVH
43.4%
Toxoplasma gondii
IDP92099
(
show subtarget assignments
)
8
selected
No
TGME49_105460
237842063
methionine aminopeptidase, type II, puta...
480
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1B6A
44.8%
Toxoplasma gondii
IDP92098
(
show subtarget assignments
)
8
selected
No
TGME49_090670
211966125
cytosol aminopeptidase [Toxoplasma gondi...
563
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3KQX
41.2%
Toxoplasma gondii
IDP92097
(
show subtarget assignments
)
8
selected
No
TGME49_086210
237839921
serine/threonine protein phosphatase, pu...
338
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2IE3
57.4%
Toxoplasma gondii
IDP92096
(
show subtarget assignments
)
8
selected
No
TGME49_056970
237831293
vacuolar ATP synthase catalytic subunit ...
616
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3M4Y
51.1%
Toxoplasma gondii
IDP92095
(
show subtarget assignments
)
8
selected
No
TGME49_046920
237835543
glutathione reductase, putative [Toxopla...
483
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1GER
46.2%
Toxoplasma gondii
IDP92094
(
show subtarget assignments
)
8
selected
No
TGME49_038190
237834427
DNA-directed RNA polymerase II, putative...
484
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1I3Q
20.7%
Toxoplasma gondii
IDP92093
(
show subtarget assignments
)
8
selected
No
TGME49_025050
237833761
adenosylhomocysteinase, putative [Toxopl...
477
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3OND
68.6%
Toxoplasma gondii
IDP92092
(
show subtarget assignments
)
8
selected
No
TGME49_020940
237841293
ribosomal RNA large subunit methyltransf...
342
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2PLW
25.7%
Toxoplasma gondii
IDP92091
(
show subtarget assignments
)
8
selected
No
TGME49_014210
237842913
centromere/microtubule binding protein, ...
505
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3U28
49.9%
Toxoplasma gondii
IDP92090
(
show subtarget assignments
)
8
selected
No
TGME49_121570
237844801
(3R)-hydroxymyristoyl ACP dehydrase, put...
231
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1Z6B
35.9%
Toxoplasma gondii
IDP92089
(
show subtarget assignments
)
8
selected
No
TGME49_118320
237840947
ATP-dependent Clp protease proteolytic s...
310
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3QWD
21.9%
Toxoplasma gondii
IDP92088
(
show subtarget assignments
)
8
selected
No
TGME49_118230
237840929
phosphoglycerate kinase, putative [Toxop...
417
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1LTK
60.9%
Toxoplasma gondii
IDP92087
(
show subtarget assignments
)
8
selected
No
TGME49_116330
237831005
iron-containing superoxide dismutase [To...
287
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2AWP
41.1%
Toxoplasma gondii
IDP92086
(
show subtarget assignments
)
8
selected
No
ABB03945
77819088
SOD1
iron-containing superoxide dismutase [To...
201
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2A03
59.7%
Toxoplasma gondii
IDP92085
(
show subtarget assignments
)
8
selected
No
TGME49_116190
237830977
superoxide dismutase, putative [Toxoplas...
258
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2BPI
41.9%
Toxoplasma gondii
IDP92084
(
show subtarget assignments
)
8
selected
No
TGME49_112250
237830299
DNA-directed RNA polymerase III subunit,...
106
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3QT1
41.3%
Toxoplasma gondii
IDP92083
(
show subtarget assignments
)
8
selected
No
TGME49_109210
237829785
peroxidoxin 2 [Toxoplasma gondii ME49]
224
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1PRX
54%
Toxoplasma gondii
IDP92082
(
show subtarget assignments
)
8
selected
No
TGME49_107570
237845455
glycerol-3-phosphate dehydrogenase, puta...
401
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1X0V
42.4%
Toxoplasma gondii
IDP92081
(
show subtarget assignments
)
8
selected
No
TGME49_106970
237845145
thymidylate kinase, putative [Toxoplasma...
273
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1E2D
35.2%
Toxoplasma gondii
IDP92080
(
show subtarget assignments
)
8
selected
No
TGME49_105290
237842049
vacuolar ATP synthase subunit E, putativ...
236
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2DM9
25%
Toxoplasma gondii
IDP92079
(
show subtarget assignments
)
8
selected
No
TGME49_101120
237844673
acetyil CoA acetyltransferase/thiolase, ...
413
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2F2S
45.9%
Toxoplasma gondii
IDP92078
(
show subtarget assignments
)
8
selected
No
TGME49_097840
237843813
DNA primase, large subunit, putative [To...
584
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3L9Q
12.7%
Toxoplasma gondii
IDP92077
(
show subtarget assignments
)
8
selected
No
TGME49_097370
237843739
ruvB-like 1, putative [Toxoplasma gondii...
463
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2C9O
62.9%
Toxoplasma gondii
IDP92076
(
show subtarget assignments
)
8
selected
No
TGME49_097060
237843677
phosphoglycerate mutase 1, putative [Tox...
265
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1XQ9
70.2%
Toxoplasma gondii
IDP92075
(
show subtarget assignments
)
8
selected
No
TGME49_095690
237844421
ubiquinone/menaquinone biosynthesis meth...
392
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1XXL
8.2%
Toxoplasma gondii
IDP92074
(
show subtarget assignments
)
8
selected
No
TGME49_095350
237844373
nucleoside diphosphate kinase, putative ...
155
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1NDL
66.5%
Toxoplasma gondii
IDP92073
(
show subtarget assignments
)
8
selected
No
TGME49_088860
237838049
ruvB-like 2 protein, putative [Toxoplasm...
508
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2XSZ
49.2%
Toxoplasma gondii
IDP92072
(
show subtarget assignments
)
8
selected
No
TGME49_087210
237840039
proteasome subunit alpha type 2, putativ...
236
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3UNB
64%
Toxoplasma gondii
IDP92071
(
show subtarget assignments
)
8
selected
No
TGME49_011680
211968957
protein disulfide isomerase [Toxoplasma ...
471
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3F8U
33.5%
Toxoplasma gondii
IDP92070
(
show subtarget assignments
)
8
selected
No
TGME49_084010
237839683
DNA polymerase I, putative [Toxoplasma g...
461
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1BGX
16.9%
Toxoplasma gondii
IDP92069
(
show subtarget assignments
)
8
selected
No
TGME49_081920
237844207
vacuolar ATP synthase subunit D, putativ...
245
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3A5C
29.8%
Toxoplasma gondii
IDP92068
(
show subtarget assignments
)
8
selected
No
TGME49_078050
237842421
proteasome subunit alpha type 1, putativ...
247
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3UNB
50.6%
Toxoplasma gondii
IDP92067
(
show subtarget assignments
)
8
selected
No
TGME49_069430
237832673
hexaprenyl pyrophosphate synthetase prot...
536
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3APZ
23.9%
Toxoplasma gondii
IDP92066
(
show subtarget assignments
)
8
selected
No
ABO93620
144228223
GAPDH2
apicoplast glyceraldehyde-3-phosphate de...
995
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3STH
20.3%
Toxoplasma gondii
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