|
|---|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Selection
Phase |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP02644
(show subtarget assignments)
|
1 |
purified |
No |
FTT0074 |
56707253 |
sdhA |
succinate dehydrogenase, catalytic and N... |
597 |
Phase 3: June 2008 |
1NEK
|
61.4% |
Francisella tularensis |
Energy metabolism |
TCA cycle |
|
|
|
IDP02646
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1290 |
29541858 |
dnaK |
chaperone protein dnak [Coxiella burneti... |
656 |
Phase 3: June 2008 |
2KHO
|
68.9% |
Coxiella burnetii |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP01886
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM0085 |
16763475 |
yabF |
glutathione-regulated potassium-efflux s... |
176 |
Phase 3: June 2008 |
3EYW
|
87.5% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP01883
(show subtarget assignments)
|
1 |
expressed |
No |
STM0116 |
16763506 |
ilvI |
acetolactate synthase 3 catalytic subuni... |
553 |
Phase 3: June 2008 |
1JSC
|
43.7% |
Salmonella enterica |
Amino acid biosynthesis |
Pyruvate family |
|
|
|
IDP01901
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM0890 |
16764251 |
artI |
arginine transport system [Salmonella ty... |
243 |
Phase 3: June 2008 |
2Y7I
|
51.4% |
Salmonella enterica |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP01887
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA5729 |
47531065 |
spo0J |
stage 0 sporulation protein J [Bacillus ... |
256 |
Phase 3: June 2008 |
1VZ0
|
36.3% |
Bacillus anthracis |
Cellular processes |
Sporulation and germination |
|
|
|
IDP02648
(show subtarget assignments)
|
1 |
soluble |
No |
FTT0064 |
56707243 |
atpD |
F0F1 ATP synthase subunit beta [Francise... |
458 |
Phase 3: June 2008 |
3OAA
|
81.3% |
Francisella tularensis |
Energy metabolism |
ATP-proton motive force interconversion |
|
|
|
IDP02624
(show subtarget assignments)
|
1 |
soluble |
No |
FTT1562 |
56708589 |
ispA |
geranyltranstransferase [Francisella tul... |
293 |
Phase 3: June 2008 |
2FOR
|
40.3% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP02625
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4457 |
47529752 |
aroK |
shikimate kinase [Bacillus anthracis str... |
165 |
Phase 3: June 2008 |
1ZUH
|
35.2% |
Bacillus anthracis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP02628
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2923 |
16766229 |
|
putative cytoplasmic protein [Salmonella... |
78 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01902
(show subtarget assignments)
|
1 |
soluble |
No |
STM0878 |
16764240 |
potG |
putrescine transporter ATP-binding subun... |
377 |
Phase 3: June 2008 |
1V43
|
38.7% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02622
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0109 |
29540729 |
|
ABC transporter, periplasmic substrate-b... |
267 |
Phase 3: June 2008 |
3TQW
|
88.4% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02629
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_1006 |
29541588 |
bioF |
8-amino-7-oxononanoate synthase [Coxiell... |
384 |
Phase 3: June 2008 |
1BS0
|
37.8% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP02670
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4353 |
47529649 |
argB |
acetylglutamate kinase [Bacillus anthrac... |
255 |
Phase 3: June 2008 |
2BTY
|
43.1% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP01871
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1795c |
56708783 |
trpC |
bifunctional indole-3-glycerol phosphate... |
453 |
Phase 3: June 2008 |
1PII
|
56.1% |
Francisella tularensis |
Amino acid biosynthesisFatty acid and phospholipid metabolism |
Aromatic amino acid familyHistidine family,Biosynthesis |
|
|
|
IDP02616
(show subtarget assignments)
|
1 |
in_pdb
3LHQ |
Yes |
STM0477 |
16763857 |
acrR |
DNA-binding transcriptional repressor Ac... |
217 |
Phase 3: June 2008 |
3LHQ
|
100% |
Salmonella enterica |
Transport and binding proteins |
Other |
|
|
|
IDP01879
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1804c |
56708790 |
rng |
ribonuclease G [Francisella tularensis s... |
498 |
Phase 3: June 2008 |
2BX2
|
31.9% |
Francisella tularensis |
Cellular processesTranscription |
Cell divisionRNA processing |
|
|
|
IDP01869
(show subtarget assignments)
|
1 |
purified |
No |
STM1467 |
16764813 |
manA |
mannose-6-phosphate isomerase [Salmonell... |
391 |
Phase 3: June 2008 |
2WFP
|
100% |
Salmonella enterica |
Energy metabolism |
Sugars |
|
|
|
IDP02143
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0739 |
29541339 |
clpX |
ATP-dependent Clp protease, ATP-binding ... |
422 |
Phase 3: June 2008 |
3HTE
|
59.5% |
Coxiella burnetii |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02618
(show subtarget assignments)
|
1 |
cloned |
No |
STM2205 |
16765535 |
fruK |
1-phosphofructokinase [Salmonella typhim... |
312 |
Phase 3: June 2008 |
3CQD
|
31.1% |
Salmonella enterica |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP02604
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1893 |
29542450 |
aroB |
3-dehydroquinate synthase [Coxiella burn... |
360 |
Phase 3: June 2008 |
3OKF
|
48.6% |
Coxiella burnetii |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP02607
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0101 |
29540723 |
nadB |
L-aspartate oxidase [Coxiella burnetii R... |
536 |
Phase 3: June 2008 |
1CHU
|
52.4% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridine nucleotides |
|
|
|
IDP02608
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0178 |
29540794 |
|
ABC transporter, ATP-binding protein [Co... |
252 |
Phase 3: June 2008 |
1V43
|
43.3% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02600
(show subtarget assignments)
|
1 |
expressed |
No |
STM2279 |
16765606 |
yfaE |
2Fe-2S ferredoxin YfaE [Salmonella typhi... |
84 |
Phase 3: June 2008 |
1IUE
|
37.2% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01880
(show subtarget assignments)
|
1 |
in_pdb
3N77
3OGA |
Yes |
STM2295 |
16765622 |
yfaO |
putative NTP pyrophosphohydrolase [Salmo... |
141 |
Phase 3: June 2008 |
3OGA
|
100% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02615
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA4677 |
47529976 |
|
ribonuclease [Bacillus anthracis str. 'A... |
458 |
Phase 3: June 2008 |
2BX2
|
27.7% |
Bacillus anthracis |
Cellular processes |
Cell division |
|
|
|
IDP02630
(show subtarget assignments)
|
1 |
expressed |
No |
STM2899 |
16766205 |
invF |
invasion regulatory protein [Salmonella ... |
216 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02592
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA1308 |
47526573 |
|
glycolate oxidase, iron-sulfur subunit, ... |
442 |
Phase 3: June 2008 |
|
|
Bacillus anthracis |
Energy metabolism |
Other |
|
|
|
IDP02587
(show subtarget assignments)
|
1 |
cloned |
No |
STM2571 |
16765891 |
murQ |
N-acetylmuramic acid-6-phosphate etheras... |
297 |
Phase 3: June 2008 |
1NRI
|
51.9% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02177
(show subtarget assignments)
|
1 |
soluble |
No |
FTT0063 |
56707242 |
atpG |
F0F1 ATP synthase subunit gamma [Francis... |
298 |
Phase 3: June 2008 |
3OAA
|
49.7% |
Francisella tularensis |
Energy metabolism |
ATP-proton motive force interconversion |
|
|
|
IDP02153
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0884 |
29541475 |
bipA |
virulence regulator BipA [Coxiella burne... |
602 |
Phase 3: June 2008 |
3E3X
|
34.6% |
Coxiella burnetii |
Cellular processes |
Pathogenesis |
|
|
|
IDP02268
(show subtarget assignments)
|
1 |
expressed |
No |
FTT1133 |
56708209 |
pilB |
Type IV pili nucleotide binding protein,... |
592 |
Phase 3: June 2008 |
1P9R
|
31.1% |
Francisella tularensis |
Cell envelope |
Surface structures |
|
|
|
IDP02594
(show subtarget assignments)
|
1 |
soluble |
No |
STM1539 |
16764884 |
|
putative hydrogenase-1 small subunit [Sa... |
367 |
Phase 3: June 2008 |
3RGW
|
66.8% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP02565
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_0648 |
29541249 |
ribH |
6,7-dimethyl-8-ribityllumazine synthase ... |
151 |
Phase 3: June 2008 |
1VSW
|
47.7% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP01858
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0993 |
29541575 |
def |
peptide deformylase [Coxiella burnetii R... |
170 |
Phase 3: June 2008 |
1N5N
|
47.6% |
Coxiella burnetii |
Protein fate |
Protein modification and repair |
|
|
|
IDP02578
(show subtarget assignments)
|
1 |
expressed |
No |
STM0262 |
16763645 |
yafS |
putative SAM-dependent methyltransferase... |
240 |
Phase 3: June 2008 |
1VLM
|
11.7% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01854
(show subtarget assignments)
|
1 |
expressed |
No |
STM1246 |
16764600 |
pagC |
virulence membrane protein PAGC precurso... |
185 |
Phase 3: June 2008 |
1ORM
|
34.1% |
Salmonella enterica |
Cellular processes |
Pathogenesis |
|
|
|
IDP01855
(show subtarget assignments)
|
1 |
soluble |
No |
STM1162 |
16764518 |
dinI |
DNA damage-inducible protein I [Salmonel... |
81 |
Phase 3: June 2008 |
1GHH
|
85.2% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01853
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1669 |
29542228 |
rpoS |
RNA polymerase sigma factor RpoS [Coxiel... |
352 |
Phase 3: June 2008 |
3IYD
|
31.5% |
Coxiella burnetii |
Transcription |
Transcription factors |
|
|
|
IDP01849
(show subtarget assignments)
|
1 |
in_pdb
3L07 |
No |
FTT0892 |
56707993 |
folD |
methylenetetrahydrofolate dehydrogenase/... |
282 |
Phase 3: June 2008 |
3L07
|
100% |
Francisella tularensis |
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers |
Aspartate familyFolic acid |
|
|
|
IDP02564
(show subtarget assignments)
|
1 |
purified |
No |
GBAA0084 |
47525340 |
ispD |
2-C-methyl-D-erythritol 4-phosphate cyti... |
226 |
Phase 3: June 2008 |
1W77
|
36.7% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP01861
(show subtarget assignments)
|
1 |
in_pdb
3IGS |
No |
STM3337 |
16766632 |
nanE |
N-acetylmannosamine-6-phosphate 2-epimer... |
229 |
Phase 3: June 2008 |
3IGS
|
99.6% |
Salmonella enterica |
Energy metabolism |
Sugars |
|
|
|
IDP02205
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT0259 |
56707415 |
hemC |
hydroxymethylbilane synthase (porphobili... |
300 |
Phase 3: June 2008 |
1AH5
|
54.3% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP02583
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA5249 |
47530554 |
|
3-hydroxyacyl-CoA dehydrogenase/enoyl-Co... |
793 |
Phase 3: June 2008 |
1WDK
|
14.6% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Degradation |
|
|
|
IDP01842
(show subtarget assignments)
|
1 |
in_pdb
3SLH
4EGR
3ROI |
Yes |
CBU_0526 |
29541129 |
aroA |
3-phosphoshikimate 1-carboxyvinyltransfe... |
438 |
Phase 3: June 2008 |
3ROI
|
100% |
Coxiella burnetii |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01845
(show subtarget assignments)
|
1 |
cloned |
No |
STM0017 |
16763407 |
|
hypothetical protein STM0017 [Salmonella... |
147 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP01846
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1419 |
29541979 |
|
serine hydroxymethyltransferase [Coxiell... |
419 |
Phase 3: June 2008 |
1DFO
|
68.5% |
Coxiella burnetii |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP01841
(show subtarget assignments)
|
1 |
purified |
No |
STM2549 |
16765869 |
asrB |
anaerobic sulfite reductase subunit B [S... |
272 |
Phase 3: June 2008 |
1KRH
|
18.8% |
Salmonella enterica |
Energy metabolism |
Anaerobic |
|
|
|
IDP02561
(show subtarget assignments)
|
1 |
purified |
No |
FTT0714c |
56707833 |
kbl |
2-amino-3-ketobutyrate coenzyme A ligase... |
398 |
Phase 3: June 2008 |
1FC4
|
62.1% |
Francisella tularensis |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP02562
(show subtarget assignments)
|
1 |
purified |
No |
STM0924 |
16764286 |
|
putative CuZn superoxide dismutase [Salm... |
174 |
Phase 3: June 2008 |
2WN0
|
60.3% |
Salmonella enterica |
Cellular processes |
Detoxification |
|
|
|
IDP01838
(show subtarget assignments)
|
1 |
cloned |
No |
STM0941 |
16764303 |
ybjY |
macrolide transporter subunit MacA [Salm... |
372 |
Phase 3: June 2008 |
3FPP
|
79% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01840
(show subtarget assignments)
|
1 |
soluble |
No |
STM2861 |
16766167 |
sitA |
putative periplasmic binding protein [Sa... |
305 |
Phase 3: June 2008 |
1XVL
|
53.4% |
Salmonella enterica |
Cell envelope |
Other |
|
|
|
IDP01847
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA5416 |
47530729 |
ftsE |
cell division ABC transporter, ATP-bindi... |
214 |
Phase 3: June 2008 |
3DHW
|
41.1% |
Bacillus anthracis |
Cellular processes |
Cell division |
|
|
|
IDP01835
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0152 |
29540772 |
coaE |
dephospho-CoA kinase [Coxiella burnetii ... |
199 |
Phase 3: June 2008 |
1JJV
|
45.7% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP02141
(show subtarget assignments)
|
1 |
purified |
No |
CBU_0737 |
29541337 |
tig |
trigger factor [Coxiella burnetii RSA 49... |
442 |
Phase 3: June 2008 |
1W26
|
41% |
Coxiella burnetii |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP02552
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0743 |
29541343 |
ptsH |
phosphocarrier protein HPr [Coxiella bur... |
89 |
Phase 3: June 2008 |
3LE1
|
46.1% |
Coxiella burnetii |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP01833
(show subtarget assignments)
|
1 |
cloned |
No |
STM2476 |
16765796 |
ypfG |
putative periplasmic protein [Salmonella... |
347 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02554
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0653 |
56707775 |
lipA |
lipoyl synthase [Francisella tularensis ... |
327 |
Phase 3: June 2008 |
|
|
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Lipoate |
|
|
|
IDP01826
(show subtarget assignments)
|
1 |
in_pdb
3LAY |
No |
STM4172 |
16767426 |
zraP |
zinc resistance protein [Salmonella typh... |
151 |
Phase 3: June 2008 |
3LAY
|
100% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01834
(show subtarget assignments)
|
1 |
soluble |
No |
STM2345 |
16765672 |
|
putative transcriptional regulator [Salm... |
339 |
Phase 3: June 2008 |
3H5O
|
33.9% |
Salmonella enterica |
Energy metabolism |
Entner-Doudoroff |
|
|
|
IDP02142
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0754 |
29541354 |
|
efflux transporter, RND family, MFP subu... |
348 |
Phase 3: June 2008 |
1VF7
|
24.7% |
Coxiella burnetii |
Transport and binding proteins |
Other |
|
|
|
IDP02673
(show subtarget assignments)
|
1 |
expressed |
No |
STM4466 |
16767711 |
|
carbamate kinase [Salmonella typhimurium... |
310 |
Phase 3: June 2008 |
1E19
|
45.5% |
Salmonella enterica |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP02543
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0275 |
29540889 |
hemE |
uroporphyrinogen decarboxylase [Coxiella... |
361 |
Phase 3: June 2008 |
3CYV
|
55.1% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP02541
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1709 |
29542267 |
dapB |
dihydrodipicolinate reductase [Coxiella ... |
239 |
Phase 3: June 2008 |
1YL5
|
42.3% |
Coxiella burnetii |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP02540
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1584 |
29542144 |
shaE |
monovalent cation/proton antiporter subu... |
115 |
Phase 3: June 2008 |
|
|
Coxiella burnetii |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP01825
(show subtarget assignments)
|
1 |
cloned |
No |
STM2265 |
16765593 |
ada |
O6-methylguanine-DNA methyltransferase/t... |
353 |
Phase 3: June 2008 |
1SFE
|
37.7% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02555
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0391 |
29541001 |
ribF |
riboflavin biosynthesis protein RibF [Co... |
320 |
Phase 3: June 2008 |
1MRZ
|
33.1% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP02832
(show subtarget assignments)
|
1 |
expressed |
No |
FTT1518 |
56708554 |
ogt |
methylated-DNA--protein-cysteine methylt... |
190 |
Phase 3: June 2008 |
1SFE
|
28.9% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy |
Heme, porphyrin, and cobalaminOther,tRNA and rRNA base modification |
|
|
|
IDP02537
(show subtarget assignments)
|
0 |
work_stopped |
No |
GBAA4558 |
47778307 |
nadD |
nicotinic acid mononucleotide adenylyltr... |
171 |
Phase 3: June 2008 |
2QTM
|
99.4% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridine nucleotides |
|
|
|
IDP02530
(show subtarget assignments)
|
1 |
soluble |
No |
FTT1674 |
56708684 |
ribH |
riboflavin synthase beta subunit (6,7-di... |
147 |
Phase 3: June 2008 |
1RVV
|
45.6% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP01824
(show subtarget assignments)
|
1 |
cloned |
No |
STM3197 |
16766497 |
glgS |
glycogen synthesis protein GlgS [Salmone... |
69 |
Phase 3: June 2008 |
1RRZ
|
73.9% |
Salmonella enterica |
Energy metabolism |
Biosynthesis and degradation of polysaccharides |
|
|
|
IDP02525
(show subtarget assignments)
|
1 |
in_pdb
4EP1 |
No |
GBAA4351 |
47529646 |
argF |
ornithine carbamoyltransferase [Bacillus... |
316 |
Phase 3: June 2008 |
4EP1
|
99.7% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP02270
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_1424 |
29541984 |
hemB |
porphobilinogen synthase [Coxiella burne... |
334 |
Phase 3: June 2008 |
1W1Z
|
48.8% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP01903
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM0750 |
16764120 |
ybgF |
hypothetical protein STM0750 [Salmonella... |
262 |
Phase 3: June 2008 |
2WZ7
|
25.6% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02584
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM1301 |
16764652 |
|
pyrimidine (deoxy)nucleoside triphosphat... |
138 |
Phase 3: June 2008 |
2RRK
|
75.4% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01815
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1382 |
29541947 |
uppS |
undecaprenyl diphosphate synthase [Coxie... |
237 |
Phase 3: June 2008 |
1JP3
|
49.4% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP01816
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM3193 |
16766493 |
|
putative disulfide bond formation protei... |
223 |
Phase 3: June 2008 |
3L9U
|
89.2% |
Salmonella enterica |
Protein synthesis |
Translation factors |
|
|
|
IDP01813
(show subtarget assignments)
|
1 |
purified |
No |
GBAA1253 |
47526519 |
trpB |
tryptophan synthase subunit beta [Bacill... |
397 |
Phase 3: June 2008 |
1X1Q
|
63% |
Bacillus anthracis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01814
(show subtarget assignments)
|
1 |
expressed |
No |
STM1753 |
16765097 |
hnr |
response regulator of RpoS [Salmonella t... |
337 |
Phase 3: June 2008 |
3EOD
|
35.3% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP01817
(show subtarget assignments)
|
1 |
cloned |
No |
STM1143 |
16764499 |
csgB |
curlin minor subunit [Salmonella typhimu... |
151 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Cellular processes |
Pathogenesis |
|
|
|
IDP02507
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1298 |
56708357 |
ubiB |
2-polyprenylphenol 6-hydroxylase [Franci... |
552 |
Phase 3: June 2008 |
|
|
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP01811
(show subtarget assignments)
|
1 |
expressed |
No |
FTT0908 |
56708009 |
parB |
chromosome partition protein B [Francise... |
304 |
Phase 3: June 2008 |
1VZ0
|
23.7% |
Francisella tularensis |
Cellular processes |
Cell division |
|
|
|
IDP02509
(show subtarget assignments)
|
1 |
crystallized |
No |
STM1809 |
16765150 |
|
putative cytoplasmic protein [Salmonella... |
57 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02511
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1359 |
29541924 |
sufC |
ABC transporter, ATP-binding protein [Co... |
244 |
Phase 3: June 2008 |
2D3W
|
63.1% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP01812
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1764c |
56708759 |
|
ferredoxin [Francisella tularensis subsp... |
107 |
Phase 3: June 2008 |
1A6L
|
64.5% |
Francisella tularensis |
Energy metabolism |
Electron transport |
|
|
|
IDP02514
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_0116 |
29540736 |
mraW |
S-adenosyl-methyltransferase MraW [Coxie... |
307 |
Phase 3: June 2008 |
1WG8
|
46.9% |
Coxiella burnetii |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP01810
(show subtarget assignments)
|
1 |
cloned |
No |
STM3187 |
16766487 |
ygiB |
hypothetical protein STM3187 [Salmonella... |
223 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01819
(show subtarget assignments)
|
1 |
cloned |
No |
STM1145 |
16764501 |
csgC |
putative autoagglutination protein [Salm... |
108 |
Phase 3: June 2008 |
2Y2T
|
64.8% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP01805
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1084 |
29541658 |
|
sensory box sensor histidine kinase/resp... |
683 |
Phase 3: June 2008 |
2C2A
|
12.4% |
Coxiella burnetii |
Signal transduction |
Two-component systems |
|
|
|
IDP02492
(show subtarget assignments)
|
1 |
crystallized |
No |
FTT1559c |
56708586 |
proC |
pyrroline-5-carboxylate reductase [Franc... |
274 |
Phase 3: June 2008 |
3TRI
|
37.6% |
Francisella tularensis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP02497
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1287 |
56708346 |
cbs |
cystathionine beta-synthase (cystein syn... |
307 |
Phase 3: June 2008 |
4AEC
|
33.2% |
Francisella tularensis |
Amino acid biosynthesis |
Serine family |
|
|
|
IDP01803
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_0646 |
29541247 |
ribE |
riboflavin synthase, alpha subunit [Coxi... |
202 |
Phase 3: June 2008 |
1I8D
|
37.7% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP02134
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_0597 |
29541198 |
|
oxygen-independent coproporphyrinogen II... |
375 |
Phase 3: June 2008 |
1OLT
|
20.3% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP02482
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1857 |
29542411 |
oppD |
peptide ABC transporter, ATP-binding pro... |
530 |
Phase 3: June 2008 |
3PIH
|
24.4% |
Coxiella burnetii |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP02516
(show subtarget assignments)
|
1 |
purified |
No |
FTT1696 |
56708705 |
groEL |
chaperonin GroEL [Francisella tularensis... |
544 |
Phase 3: June 2008 |
1AON
|
73.3% |
Francisella tularensis |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP02469
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0573 |
56707702 |
alr |
alanine racemase [Francisella tularensis... |
365 |
Phase 3: June 2008 |
4A3Q
|
31.7% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP01797
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1008 |
29541590 |
bioA |
adenosylmethionine-8-amino-7-oxononanoat... |
442 |
Phase 3: June 2008 |
3DOD
|
35.4% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP02483
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0517 |
29541120 |
aspB |
aspartate aminotransferase [Coxiella bur... |
394 |
Phase 3: June 2008 |
1BJW
|
43.9% |
Coxiella burnetii |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP01793
(show subtarget assignments)
|
1 |
in_pdb
3QDN |
No |
STM0504 |
16763884 |
ybbN |
putative thioredoxin protein [Salmonella... |
284 |
Phase 3: June 2008 |
3QDN
|
100% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP02127
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1116c |
56708194 |
yajC |
preprotein translocase family protein [F... |
118 |
Phase 3: June 2008 |
2RDD
|
17.8% |
Francisella tularensis |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
