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Targets
Filter Targets:
Selection Phase:
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Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 10 of 60, showing 100 records out of 5973 total, starting on record 901
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90936
(
show subtarget assignments
)
8
cloned
No
YPO2016
16122259
hemA
glutamyl-tRNA reductase [Yersinia pestis...
420
Predicted Essential
Community Requests
1GPJ
32.9%
Yersinia pestis
IDP90937
(
show subtarget assignments
)
8
cloned
No
YPO0110
16120456
priA
primosome assembly protein PriA
732
Predicted Essential
Community Requests
2EYQ
9.4%
Yersinia pestis
IDP90941
(
show subtarget assignments
)
8
expressed
No
NMPDR 214092.1.peg.4098
246
Predicted Essential
Community Requests
2PB0
66.3%
Yersinia pestis
IDP90942
(
show subtarget assignments
)
8
expressed
No
A55_2372
124113375
ispE
4-diphosphocytidyl-2C-methyl-D-erythrito...
194
We have identified the methylerythritol phosphate (MEP) pathway enzymes, novel d...
Community Requests
1OJ4
59.8%
Vibrio cholerae
IDP90944
(
show subtarget assignments
)
8
cloned
No
STM1121
16764478
ymdF
putative cytoplasmic protein [Salmonella...
55
This is a protein with experimental and computational evidence for being secrete...
Community Requests
Salmonella enterica
IDP90945
(
show subtarget assignments
)
8
purified
No
VP0092
28896866
hypothetical protein VP0092 [Vibrio para...
811
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3HVB
13.7%
Vibrio parahaemolyticus
IDP90948
(
show subtarget assignments
)
8
cloned
No
M5005_Spy_1720
71911533
mga
trans-acting positive regulator [Strepto...
529
The multiple gene regulator of the Group A Streptococcus (Mga) is an established...
Community Requests
Streptococcus pyogenes
IDP90949
(
show subtarget assignments
)
8
purified
No
ZZZ_0019
20986512
MAPK14
mitogen-activated protein kinase 14 isof...
360
Drug Target
Community Requests
1A9U
100%
Homo sapiens
IDP90951
(
show subtarget assignments
)
8
purified
No
VC0653
81545356
C-di-GMP phosphodiesterase A-related pro...
684
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
15.5%
Vibrio cholerae
IDP90952
(
show subtarget assignments
)
8
soluble
No
UTI89_C2726
122422986
Hypothetical protein yfeA
749
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
13.4%
Escherichia coli
IDP90957
(
show subtarget assignments
)
8
cloned
No
PFL_1902
123656875
Sensory box-containing diguanylate cycla...
572
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
18.4%
Pseudomonas fluorescens
IDP90958
(
show subtarget assignments
)
8
cloned
No
UTI89_C1702
122423767
Hypothetical protein
807
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
1V9Y
18%
Escherichia coli
IDP90960
(
show subtarget assignments
)
8
expressed
No
VC0658
81545351
C-di-GMP phosphodiesterase A-related pro...
685
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
18.7%
Vibrio cholerae
IDP90961
(
show subtarget assignments
)
8
purified
No
VP0117
81728759
GGDEF family protein
848
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
12.3%
Vibrio parahaemolyticus
IDP90964
(
show subtarget assignments
)
8
purified
No
VC0072
81545617
Sensory box/GGDEF family protein
768
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
15.4%
Vibrio cholerae
IDP90965
(
show subtarget assignments
)
8
purified
No
VF0094
75354809
Sensory box/GGDEF family protein
852
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
11.2%
Vibrio fischeri
IDP90967
(
show subtarget assignments
)
8
cloned
No
UTI89_C2819
122422922
Hypothetical protein yfgF
747
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3HVB
14.2%
Escherichia coli
IDP90968
(
show subtarget assignments
)
8
selected
No
427
Planet Biotechnology company is currently developing an anthrax anti-toxin with ...
Community Requests
1HZH
62.3%
synthetic construct
IDP90976
(
show subtarget assignments
)
8
cloned
No
y0137
22124057
degQ
protease [Yersinia pestis KIM 10]
463
other biological interest /
bifunctional chaperone / protease
Community Requests
4A8A
67.6%
Yersinia pestis
IDP90977
(
show subtarget assignments
)
8
soluble
No
y0320
22124237
oxyR
DNA-binding transcriptional regulator Ox...
305
other biological interest /
important global regulator
Community Requests
1I6A
59.7%
Yersinia pestis
IDP90979
(
show subtarget assignments
)
8
cloned
No
y0636
22124550
hypothetical protein y0636 [Yersinia pes...
158
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
2Y75
24.1%
Yersinia pestis
IDP90980
(
show subtarget assignments
)
8
cloned
No
y0801
22124714
iron-sulfur cluster insertion protein Er...
119
other biological interest /
protein possibly involved in iron-sulfur cluster synthesis
Community Requests
2APN
75.6%
Yersinia pestis
IDP90983
(
show subtarget assignments
)
8
selected
No
y0870
22124781
katG
catalase-peroxidase [Yersinia pestis KIM...
751
virulence/pathogenesis /
stress response protein and antigen in Y pestis
Community Requests
2FXG
59.4%
Yersinia pestis
IDP90984
(
show subtarget assignments
)
8
cloned
No
y0931
22124839
hypothetical protein y0931 [Yersinia pes...
281
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3SHO
12.8%
Yersinia pestis
IDP90986
(
show subtarget assignments
)
8
cloned
No
y0974
22124881
rdgC
recombination associated protein [Yersin...
303
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
2OWL
83.2%
Yersinia pestis
IDP90987
(
show subtarget assignments
)
8
crystallized
No
y1125
22125029
hypothetical protein y1125 [Yersinia pes...
297
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
1VP5
57.2%
Yersinia pestis
IDP90993
(
show subtarget assignments
)
8
selected
No
y1334
22125233
cysteine desulfurase [Yersinia pestis KI...
409
other biological interest /
enzyme involved in iron-sulfur cluster synthesis
Community Requests
1P3W
87.8%
Yersinia pestis
IDP90994
(
show subtarget assignments
)
8
purified
No
y1355
22125254
hypothetical protein y1355 [Yersinia pes...
211
other biological interest /
-
Community Requests
Yersinia pestis
IDP90996
(
show subtarget assignments
)
8
in_pdb
4DYU
No
y1677
22125572
dps
DNA starvation/stationary phase protecti...
167
other biological interest /
global stress response protein
Community Requests
4DYU
100%
Yersinia pestis
IDP90997
(
show subtarget assignments
)
8
soluble
No
y1682
22125577
ompX
outer membrane protein X [Yersinia pesti...
176
virulence/pathogenesis /
putative cell surface adhesin in various Gram-negative pathogens
Community Requests
1ORM
59.1%
Yersinia pestis
IDP91000
(
show subtarget assignments
)
8
cloned
No
y1726
22125620
hypothetical protein y1726 [Yersinia pes...
334
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91001
(
show subtarget assignments
)
8
soluble
No
y1897
22125790
yfeA
periplasmic-binding protein [Yersinia pe...
323
virulence/pathogenesis /
periplasmic iron-binding protein
Community Requests
1XVL
52.9%
Yersinia pestis
IDP91003
(
show subtarget assignments
)
8
soluble
No
y1934
22125826
sufA
iron-sulfur cluster assembly scaffold pr...
132
potential drug target /
part of iron-sulfur cluster assembly system active under stress conditions
Community Requests
2D2A
59.8%
Yersinia pestis
IDP91004
(
show subtarget assignments
)
8
soluble
No
y1935
22125827
cysteine desulfurase activator complex s...
503
potential drug target /
part of iron-sulfur cluster assembly system active under stress conditions
Community Requests
4DN7
18.7%
Yersinia pestis
IDP91008
(
show subtarget assignments
)
8
soluble
No
y1951
22125843
sodB
superoxide dismutase [Yersinia pestis KI...
206
other biological interest /
iron-regulated oxidative stress enzyme
Community Requests
1ISA
75.2%
Yersinia pestis
IDP91009
(
show subtarget assignments
)
8
soluble
No
y2136
22126024
hypothetical protein y2136 [Yersinia pes...
317
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91011
(
show subtarget assignments
)
8
purified
No
y2255
22126141
hypothetical protein y2255 [Yersinia pes...
251
other biological interest /
possibly involved in quorum sensing
Community Requests
1KON
83.3%
Yersinia pestis
IDP91012
(
show subtarget assignments
)
8
expressed
No
y2259
22126145
hypothetical protein y2259 [Yersinia pes...
271
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91015
(
show subtarget assignments
)
8
selected
No
y2404
22126288
psn
pesticin/yersiniabactin outer membrane r...
673
TonB-dependent outer membrane receptor (yersiniabactin-binding)
Community Requests
1NQF
23.8%
Yersinia pestis
IDP91016
(
show subtarget assignments
)
8
selected
No
y2451
22126334
hypothetical protein y2451 [Yersinia pes...
384
other biological interest /
putative iron transport protein
Community Requests
3AT7
40.9%
Yersinia pestis
IDP91018
(
show subtarget assignments
)
8
cloned
No
y2737
22126615
hypothetical protein y2737 [Yersinia pes...
164
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91019
(
show subtarget assignments
)
8
selected
No
y2821
22126698
poxB
pyruvate dehydrogenase [Yersinia pestis ...
573
potential drug target /
alternative pathway for aerobic energy metabolism
Community Requests
3EY9
79.2%
Yersinia pestis
IDP91024
(
show subtarget assignments
)
8
cloned
No
y2983
22126860
outer membrane protein C2 [Yersinia pest...
371
drug resistance /
anion-specific outer membrane porin
Community Requests
3HW9
59.9%
Yersinia pestis
IDP91025
(
show subtarget assignments
)
8
in_crystallization_trials
No
y3037
22126914
modA
molybdate transporter periplasmic protei...
263
other biological interest /
-
Community Requests
3R26
63.9%
Yersinia pestis
IDP91027
(
show subtarget assignments
)
8
expressed
No
y3600
22127474
uxaC
uronate isomerase [Yersinia pestis KIM]
477
other biological interest /
-
Community Requests
3IAC
64.4%
Yersinia pestis
IDP91028
(
show subtarget assignments
)
8
selected
No
y3714
22127588
hypothetical protein y3714 [Yersinia pes...
259
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91031
(
show subtarget assignments
)
8
cloned
No
y4125
22127993
solute-binding periplasmic protein precu...
284
other biological interest /
highly abundant periplasmic protein with unknown function
Community Requests
1XT8
31%
Yersinia pestis
IDP91032
(
show subtarget assignments
)
8
cloned
No
Y1069
31795399
toxin [Yersinia pestis KIM]
587
virulence/pathogenesis /
survival factor of Y pestis in the flea
Community Requests
1F0I
22.7%
Yersinia pestis
IDP91034
(
show subtarget assignments
)
8
selected
No
SDY_P055
82524461
ospC1
OspC1 [Shigella dysenteriae Sd197]
470
virulence/pathogenesis /
A cell surface protein of S. dysenteriae and putative virulence factor secreted ...
Community Requests
Shigella dysenteriae
IDP91035
(
show subtarget assignments
)
8
selected
No
SDY_P070
82524476
ospC2
OspC2 [Shigella dysenteriae Sd197]
484
virulence/pathogenesis /
A cell surface protein of S. dysenteriae and putative virulence factor secreted ...
Community Requests
Shigella dysenteriae
IDP91039
(
show subtarget assignments
)
8
selected
No
Sd1012_5151
194431100
hdeB
HdeB protein [Shigella dysenteriae 1012]...
108
potential drug target /
A protein that is important for acid resistance in some enteropathogens; it is a...
Community Requests
2XUV
65.7%
Shigella dysenteriae
IDP91041
(
show subtarget assignments
)
8
in_pdb
3TYS
3TYR
No
EFE0002
33355847
vanUG
predicted transcriptional regulator [Ent...
75
drug resistance /
Putative transcriptional regulator
Community Requests
3T75
89.3%
Enterococcus faecalis
IDP91043
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFE0003
33355848
vanRG
response regulator [Enterococcus faecali...
235
drug resistance /
Component of regulatory system of transcription of vancomycin resistance genes
Community Requests
1P2F
37%
Enterococcus faecalis
IDP91044
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFA0002
110556113
vanY
vanY [Enterococcus faecalis]
303
drug resistance /
A carboxypeptidase thought to be involved in breakdown of normal cell wall
Community Requests
Enterococcus faecalis
IDP91047
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFA0003
5353563
vanRD
response regulator [Enterococcus faecium...
232
drug resistance /
Component of regulatory system of transcription of vancomycin resistance genes
Community Requests
2GWR
37.1%
Enterococcus faecium
IDP91048
(
show subtarget assignments
)
8
in_crystallization_trials
No
EGA0001
4545123
vanT
serine racemase VanT [Enterococcus galli...
698
drug resistance /
Serine racemase involved in synthesis of D-Ala-D-Ser, a component of vancomycin ...
Community Requests
4ECL
22.3%
Enterococcus gallinarum
IDP91050
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFE0001
1209531
vanB
D-Ala:D-Lac ligase [Enterococcus faecali...
342
drug resistance /
D-lactate D-ala ligase; generates vancomycin resistant cell wall
Community Requests
1E4E
75.1%
Enterococcus faecalis
IDP91051
(
show subtarget assignments
)
8
in_crystallization_trials
No
PRM0001
81687074
rmtC
16S rRNA methylase [Proteus mirabilis]
281
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3B89
29.2%
Proteus mirabilis
IDP91059
(
show subtarget assignments
)
8
soluble
No
FTT_1472c
56708512
ppiC
peptidyl-prolyl cis-trans isomerase [Fra...
92
virulence/pathogenesis /
Gene encodes a SurA orthologue which has shown to be important for virulence in ...
Community Requests
1JNS
47.8%
Francisella tularensis
IDP91061
(
show subtarget assignments
)
8
purified
No
YPO3532
16123678
fklB
FKBP-type peptidyl-prolyl cis-trans isom...
206
virulence/pathogenesis /
Gene encodes a Mip orthologue which has shown to be important for virulence in v...
Community Requests
1FD9
38.8%
Yersinia pestis
IDP91065
(
show subtarget assignments
)
8
expressed
No
VC0395_A0354
147674291
tcpB
toxin co-regulated pilus biosynthesis pr...
430
vaccine candidate /
For Vibrio cholerae to colonize the human intestine and cause cholera, it must e...
Community Requests
Vibrio cholerae
IDP91068
(
show subtarget assignments
)
8
cloned
No
VF_A0424
59713607
msbA
lipid transporter ATP-binding/permease p...
582
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5X
75.1%
Vibrio fischeri
IDP91071
(
show subtarget assignments
)
8
cloned
No
NGO2165
59719354
putative ABC transporter, ATP-binding pr...
622
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5Y
34.2%
Neisseria gonorrhoeae
IDP91072
(
show subtarget assignments
)
8
cloned
No
YPO2588
16122801
-
putative ABC transport protein
631
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
32.2%
Yersinia pestis
IDP91074
(
show subtarget assignments
)
8
cloned
No
MSMEG_5659
118469658
ABC transporter, ATP-binding protein [My...
610
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
32.1%
Mycobacterium smegmatis
IDP91075
(
show subtarget assignments
)
8
cloned
No
jhp0343
15611411
msbA
multi-drug resistance protein [Helicobac...
551
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5W
31.4%
Helicobacter pylori
IDP91079
(
show subtarget assignments
)
8
cloned
No
BMA0204
53725011
ABC transporter, ATP-binding/permease pr...
623
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
4AA3
32.8%
Burkholderia mallei
IDP91080
(
show subtarget assignments
)
8
cloned
No
Cj0803
6968244
msbA
lipid export ABC transport protein
580
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
31.6%
Campylobacter jejuni
IDP91082
(
show subtarget assignments
)
8
cloned
No
CPF_1776
110800219
ABC transporter, permease/ATP-binding pr...
589
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
39.2%
Clostridium perfringens
IDP91083
(
show subtarget assignments
)
8
cloned
No
BA_0528
30260686
ABC transporter, ATP-binding/permease pr...
586
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
58.2%
Bacillus anthracis
IDP91087
(
show subtarget assignments
)
8
expressed
No
BMA_3102
52427493
carbohydrate isomerase, KpsF/GutQ family...
327
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
30.9%
Burkholderia mallei
Energy metabolism: Sugars
IDP91088
(
show subtarget assignments
)
8
cloned
No
BMA_2275
52429282
kdsB
3-deoxy-D-manno-octulosonate cytidylyltr...
263
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3K8D
52.1%
Burkholderia mallei
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP91090
(
show subtarget assignments
)
8
cloned
No
aq_1546
15606685
kpsF
polysialic acid capsule expression prote...
322
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
25.5%
Aquifex aeolicus
IDP91091
(
show subtarget assignments
)
8
cloned
No
APL_0387
126096663
kpsF
arabinose-5-phosphate isomerase [Actinob...
311
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
27%
Actinobacillus pleuropneumoniae
IDP91106
(
show subtarget assignments
)
8
in_pdb
3QFK
Yes
SAOUHSC_00107
88193920
hypothetical protein SAOUHSC_00107 [Stap...
511
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3QFK
99.8%
Staphylococcus aureus
IDP01076
(
show subtarget assignments
)
8
expressed
No
STM4120
16767385
argE
acetylornithine deacetylase
383
Drug Target Function
Community Requests
3CT9
25.1%
Salmonella enterica
Amino acid biosynthesis
Glutamate family
IDP91154
(
show subtarget assignments
)
8
in_pdb
3QFG
Yes
SAOUHSC_00808
88194568
hypothetical protein SAOUHSC_00808 [Stap...
242
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3QFG
93.4%
Staphylococcus aureus
IDP91163
(
show subtarget assignments
)
8
cloned
No
VC1507
15641516
phospho-2-dehydro-3-deoxyheptonate aldol...
395
potential drug target /
Shikimate pathway enzyme
Community Requests
1GG1
48.9%
Vibrio cholerae
IDP91166
(
show subtarget assignments
)
8
in_pdb
3T4E
No
STM1359
16764710
aroE
shikimate 5-dehydrogenase
288
potential drug target /
Shikimate pathway enzyme
Community Requests
3T4E
100%
Salmonella enterica
IDP91167
(
show subtarget assignments
)
8
expressed
No
STM3401
16766690
aroE
shikimate 5-dehydrogenase
272
potential drug target /
Shikimate pathway enzyme
Community Requests
1NYT
84.9%
Salmonella enterica
IDP91169
(
show subtarget assignments
)
8
in_pdb
3TNL
3TOZ
No
lmo0490
16802533
-
similar to shikimate 5-dehydrogenase
291
potential drug target /
Shikimate pathway enzyme
Community Requests
3TNL
100%
Listeria monocytogenes
IDP91170
(
show subtarget assignments
)
8
cloned
No
lmo2236
16804275
-
similar to oxidoreductase
289
potential drug target /
Shikimate pathway enzyme
Community Requests
3TNL
52.6%
Listeria monocytogenes
IDP91180
(
show subtarget assignments
)
8
cloned
No
CT576
15605305
lcrH_1
low calcium response protein H [Chlamydi...
232
virulence/pathogenesis /
Targets that are in a network of interactions with CT670 and CT671. These protei...
Community Requests
2VGX
19%
Chlamydia trachomatis
IDP91181
(
show subtarget assignments
)
8
cloned
No
CT578
3329020
wall surface anchor family protein [Chla...
487
virulence/pathogenesis /
Targets that are in a network of interactions with CT670 and CT671. These protei...
Community Requests
Chlamydia trachomatis
IDP91183
(
show subtarget assignments
)
8
in_pdb
3T7Y
No
CT091
15604810
yscU
type III secretion system protein [Chlam...
360
virulence/pathogenesis /
Targets that are in a network of interactions with CT670 and CT671. These protei...
Community Requests
3T7Y
26.7%
Chlamydia trachomatis
IDP91185
(
show subtarget assignments
)
8
cloned
No
AAC46367
2352978
477
virulence/pathogenesis /
FlrC regulates flagellar synthesis in Vibrio cholerae, and my lab has determined...
Community Requests
1NY5
31.9%
Vibrio cholerae
IDP91195
(
show subtarget assignments
)
8
cloned
No
BAS4091
49187089
-
Stage III sporulation protein AG
220
essential/virulence/pathogenesis /
Essential proteins
Community Requests
Bacillus anthracis
IDP91196
(
show subtarget assignments
)
8
soluble
No
BAS4097
49187095
-
Stage III sporulation protein AA
308
essential/virulence/pathogenesis /
Essential proteins
Community Requests
Bacillus anthracis
IDP91198
(
show subtarget assignments
)
8
cloned
No
BAS5131
49188117
-
stage II sporulation protein
301
essential/virulence/pathogenesis /
Essential proteins
Community Requests
3TUF
33.6%
Bacillus anthracis
IDP91200
(
show subtarget assignments
)
8
cloned
No
CD1911
115250958
two-component sensor histidine kinase [C...
469
virulence/pathogenesis /
The important histidine kinase for ethanolamine utilization in anaerobic bacteri...
Community Requests
Clostridium difficile
IDP91207
(
show subtarget assignments
)
8
soluble
No
BT_2842
29348251
3-dehydroquinate dehydratase [Bacteroide...
140
potential drug target /
Shikimate pathway enzyme
Community Requests
2C4W
49%
Bacteroides thetaiotaomicron
IDP91208
(
show subtarget assignments
)
8
purified
No
BT_2186
29347596
3-phosphoshikimate 1-carboxyvinyltransfe...
410
potential drug target /
Shikimate pathway enzyme
Community Requests
1EPS
36.2%
Bacteroides thetaiotaomicron
IDP91210
(
show subtarget assignments
)
8
expressed
No
BLIJ_0364
189439941
aroG2
phospho-2-dehydro-3-deoxyheptonate aldol...
377
potential drug target /
Shikimate pathway enzyme
Community Requests
1GG1
47.7%
Bifidobacterium longum
IDP91211
(
show subtarget assignments
)
8
purified
No
BLIJ_0365
189439940
aroG1
phospho-2-dehydro-3-deoxyheptonate aldol...
410
potential drug target /
Shikimate pathway enzyme
Community Requests
1HFB
44.1%
Bifidobacterium longum
IDP91214
(
show subtarget assignments
)
8
expressed
No
Blon_1597
189439474
aroB
bifunctional shikimate kinase/3-dehydroq...
540
potential drug target /
Shikimate pathway enzyme
Community Requests
3QBD
32.6%
Bifidobacterium longum
IDP91221
(
show subtarget assignments
)
8
soluble
No
SAV1231
15924221
fabG
3-oxoacyl-(acyl-carrier protein) reducta...
246
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3OSU
100%
Staphylococcus aureus
IDP91223
(
show subtarget assignments
)
8
purified
No
SF1267
24112663
trpE
anthranilate synthase component I [Shige...
520
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1I1Q
89.2%
Shigella flexneri
IDP91224
(
show subtarget assignments
)
8
cloned
No
SF1266
24112662
trpD
bifunctional glutamine amidotransferase/...
531
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1KGZ
46.7%
Shigella flexneri
IDP91258
(
show subtarget assignments
)
8
soluble
No
NT02SA1455
14247237
aroC
chorismate synthase [Staphylococcus aure...
388
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1QXO
56.7%
Staphylococcus aureus
Amino acid biosynthesis: Aromatic amino acid family
IDP91257
(
show subtarget assignments
)
8
soluble
No
NT02SA1359
14247140
trpD
anthranilate phosphoribosyltransferase [...
332
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1VQU
33.8%
Staphylococcus aureus
Amino acid biosynthesis: Aromatic amino acid family
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