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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 11 of 60, showing 100 records out of 5973 total, starting on record 1001
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP04021
(
show subtarget assignments
)
1
expressed
No
BAS3695
49186694
30S ribosomal protein S16 [Bacillus anth...
90
Proposed to be essential proteins
Phase 4: April 2009
1EMW
42.2%
Bacillus anthracis
IDP04624
(
show subtarget assignments
)
1
in_pdb
3B2B
3UWD
No
BAS4988
49187974
phosphoglycerate kinase [Bacillus anthra...
394
Proposed to be essential proteins
Phase 4: April 2009
3B2B
99.7%
Bacillus anthracis
IDP04622
(
show subtarget assignments
)
1
soluble
No
BAS4556
49187550
tyrosyl-tRNA synthetase [Bacillus anthra...
418
potential drug target /
Proposed to be essential proteins
Phase 4: April 2009
2TS1
70.6%
Bacillus anthracis
IDP04022
(
show subtarget assignments
)
1
cloned
No
BAS0095
49183129
preprotein translocase subunit SecE [Bac...
59
Proposed to be essential proteins
Phase 4: April 2009
3DIN
33.9%
Bacillus anthracis
IDP04621
(
show subtarget assignments
)
1
cloned
No
BAS4494
49187489
acetyl-CoA carboxylase carboxyltransfera...
324
Proposed to be essential proteins
Phase 4: April 2009
2F9I
60.2%
Bacillus anthracis
IDP04628
(
show subtarget assignments
)
1
soluble
No
BAS5322
49188306
50S ribosomal protein L9 [Bacillus anthr...
148
Proposed to be essential proteins
Phase 4: April 2009
1DIV
75%
Bacillus anthracis
IDP04623
(
show subtarget assignments
)
1
expressed
No
BAS4760
49187751
glucose-1-phosphate adenylyltransferase ...
376
Proposed to be essential proteins
Phase 4: April 2009
3BRK
40%
Bacillus anthracis
IDP04616
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS4313
49187308
S-adenosylmethionine:tRNA ribosyltransfe...
350
Proposed to be essential proteins
Phase 4: April 2009
1YY3
71.4%
Bacillus anthracis
IDP04613
(
show subtarget assignments
)
1
cloned
No
BAS3890
49186888
M20/M25/M40 family peptidase [Bacillus a...
376
Proposed to be essential proteins
Phase 4: April 2009
1YSJ
35.6%
Bacillus anthracis
IDP04614
(
show subtarget assignments
)
1
purified
No
BAS4131
49187128
glycine cleavage system aminomethyltrans...
366
Proposed to be essential proteins
Phase 4: April 2009
1YX2
66.1%
Bacillus anthracis
IDP04617
(
show subtarget assignments
)
1
expressed
No
BAS4342
49187337
50S ribosomal protein L21 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1VSA
54.9%
Bacillus anthracis
IDP04615
(
show subtarget assignments
)
1
cloned
No
BAS4297
49187293
aspartyl-tRNA synthetase [Bacillus anthr...
591
Proposed to be essential proteins
Phase 4: April 2009
1EQR
52.7%
Bacillus anthracis
IDP04611
(
show subtarget assignments
)
1
cloned
No
BAS3754
49186753
sporulation sigma factor SigG [Bacillus ...
289
Proposed to be essential proteins
Phase 4: April 2009
1L0O
37%
Bacillus anthracis
IDP04610
(
show subtarget assignments
)
1
in_pdb
3RFO
No
BAS3717
49186716
methionyl-tRNA formyltransferase [Bacill...
314
Proposed to be essential proteins
Phase 4: April 2009
3RFO
100%
Bacillus anthracis
IDP04612
(
show subtarget assignments
)
1
cloned
No
BAS3764
49186763
phospho-N-acetylmuramoyl-pentapeptide-tr...
324
Proposed to be essential proteins
Phase 4: April 2009
Bacillus anthracis
IDP04609
(
show subtarget assignments
)
1
soluble
No
BAS3712
49186711
ribosome-associated GTPase [Bacillus ant...
293
Proposed to be essential proteins
Phase 4: April 2009
1T9H
63.4%
Bacillus anthracis
IDP04618
(
show subtarget assignments
)
1
cloned
No
BAS4456
49187451
phenylalanyl-tRNA synthetase subunit alp...
344
Proposed to be essential proteins
Phase 4: April 2009
2RHQ
57.6%
Bacillus anthracis
IDP04604
(
show subtarget assignments
)
1
cloned
No
BAS3678
49186677
30S ribosomal protein S2 [Bacillus anthr...
233
Proposed to be essential proteins
Phase 4: April 2009
1FJG
56.2%
Bacillus anthracis
IDP04603
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS3670
49186669
prolyl-tRNA synthetase [Bacillus anthrac...
566
Proposed to be essential proteins
Phase 4: April 2009
2J3L
58.1%
Bacillus anthracis
IDP04605
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS3689
49186688
ribosomal biogenesis GTPase [Bacillus an...
296
Proposed to be essential proteins
Phase 4: April 2009
1PUJ
67.2%
Bacillus anthracis
IDP04606
(
show subtarget assignments
)
1
cloned
No
BAS3692
49186691
tRNA (guanine-N(1)-)-methyltransferase [...
244
Proposed to be essential proteins
Phase 4: April 2009
3KY7
62.3%
Bacillus anthracis
IDP04601
(
show subtarget assignments
)
1
in_pdb
3RHI
Yes
BAS3574
49186575
DNA-binding protein HU [Bacillus anthrac...
90
Proposed to be essential proteins
Phase 4: April 2009
3RHI
100%
Bacillus anthracis
IDP04602
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS3667
49186666
transcription elongation factor NusA [Ba...
368
Proposed to be essential proteins
Phase 4: April 2009
1HH2
44%
Bacillus anthracis
IDP04600
(
show subtarget assignments
)
1
cloned
No
BAS2547
49185555
preprotein translocase subunit SecY [Bac...
434
Proposed to be essential proteins
Phase 4: April 2009
3DIN
42.2%
Bacillus anthracis
IDP04593
(
show subtarget assignments
)
1
cloned
No
BAS0144
49183178
30S ribosomal protein S9 [Bacillus anthr...
130
Proposed to be essential proteins
Phase 4: April 2009
1VS5
55.4%
Bacillus anthracis
IDP04595
(
show subtarget assignments
)
1
soluble
No
BAS0565
49183590
nicotinate phosphoribosyltransferase [Ba...
487
Proposed to be essential proteins
Phase 4: April 2009
2F7F
61.4%
Bacillus anthracis
IDP04591
(
show subtarget assignments
)
1
cloned
No
BAS0138
49183172
50S ribosomal protein L17 [Bacillus anth...
120
Proposed to be essential proteins
Phase 4: April 2009
1NKW
50.8%
Bacillus anthracis
IDP04592
(
show subtarget assignments
)
1
expressed
No
BAS0143
49183177
50S ribosomal protein L13 [Bacillus anth...
145
Proposed to be essential proteins
Phase 4: April 2009
1P85
56.6%
Bacillus anthracis
IDP04588
(
show subtarget assignments
)
1
cloned
No
BAS0130
49183164
preprotein translocase subunit SecY [Bac...
433
Proposed to be essential proteins
Phase 4: April 2009
3DIN
43.8%
Bacillus anthracis
IDP04589
(
show subtarget assignments
)
1
expressed
No
BAS0135
49183169
30S ribosomal protein S13 [Bacillus anth...
121
Proposed to be essential proteins
Phase 4: April 2009
1FJG
63.9%
Bacillus anthracis
IDP04590
(
show subtarget assignments
)
1
expressed
No
BAS0136
49183170
30S ribosomal protein S11 [Bacillus anth...
129
Proposed to be essential proteins
Phase 4: April 2009
1VS5
65.9%
Bacillus anthracis
IDP04596
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS1099
49184119
tryptophanyl-tRNA synthetase [Bacillus a...
329
Proposed to be essential proteins
Phase 4: April 2009
3PRH
73.9%
Bacillus anthracis
IDP04585
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0116
49183150
30S ribosomal protein S3 [Bacillus anthr...
219
Proposed to be essential proteins
Phase 4: April 2009
1VS5
54.3%
Bacillus anthracis
IDP04583
(
show subtarget assignments
)
1
cloned
No
BAS0111
49183145
50S ribosomal protein L4 [Bacillus anthr...
207
Proposed to be essential proteins
Phase 4: April 2009
1DMG
47.1%
Bacillus anthracis
IDP04584
(
show subtarget assignments
)
1
purified
No
BAS0112
49183146
50S ribosomal protein L23 [Bacillus anth...
96
Proposed to be essential proteins
Phase 4: April 2009
1N88
43.8%
Bacillus anthracis
IDP04586
(
show subtarget assignments
)
1
cloned
No
BAS0117
49183151
50S ribosomal protein L16 [Bacillus anth...
144
Proposed to be essential proteins
Phase 4: April 2009
1VSA
60.4%
Bacillus anthracis
IDP04587
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0118
49183152
50S ribosomal protein L29 [Bacillus anth...
66
Proposed to be essential proteins
Phase 4: April 2009
1R73
45.5%
Bacillus anthracis
IDP04582
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0110
49183144
50S ribosomal protein L3 [Bacillus anthr...
210
Proposed to be essential proteins
Phase 4: April 2009
1NKW
53.3%
Bacillus anthracis
IDP04597
(
show subtarget assignments
)
1
expressed
No
BAS1384
49184401
resB protein [Bacillus anthracis str. St...
541
Proposed to be essential proteins
Phase 4: April 2009
Bacillus anthracis
IDP05335
(
show subtarget assignments
)
1
expressed
No
BAS2222
49185231
-
threonyl-tRNA synthetase [Bacillus anthr...
639
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1NYQ
50.5%
Bacillus anthracis
Protein synthesis: tRNA aminoacylation
IDP04580
(
show subtarget assignments
)
1
cloned
No
BAS0103
49183137
DNA-directed RNA polymerase subunit beta...
1203
Proposed to be essential proteins
Phase 4: April 2009
2GHO
53.6%
Bacillus anthracis
IDP04579
(
show subtarget assignments
)
1
cloned
No
BAS0098
49183132
50S ribosomal protein L1 [Bacillus anthr...
230
Proposed to be essential proteins
Phase 4: April 2009
3QOY
56.3%
Bacillus anthracis
IDP04064
(
show subtarget assignments
)
1
expressed
No
BAS0127
49183161
30S ribosomal protein S5 [Bacillus anthr...
166
Proposed to be essential proteins
Phase 4: April 2009
1PKP
75.3%
Bacillus anthracis
IDP04598
(
show subtarget assignments
)
1
cloned
No
BAS1442
49184459
dihydrodipicolinate reductase [Bacillus ...
266
Proposed to be essential proteins
Phase 4: April 2009
1C3V
40.6%
Bacillus anthracis
IDP04581
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0108
49183142
elongation factor Tu [Bacillus anthracis...
395
Proposed to be essential proteins
Phase 4: April 2009
3U2Q
75.4%
Bacillus anthracis
IDP91597
(
show subtarget assignments
)
8
cloned
No
BAA24464
2804528
YfiX [Bacillus subtilis]
610
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Bacillus subtilis
IDP91588
(
show subtarget assignments
)
8
cloned
No
BAA24463
2804527
YfiW [Bacillus subtilis]
258
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Bacillus subtilis
IDP91593
(
show subtarget assignments
)
8
expressed
No
BSU08430
16077910
yfiX
hypothetical protein BSU08430 [Bacillus ...
606
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Bacillus subtilis
IDP91199
(
show subtarget assignments
)
1
cloned
No
BSU40540
16081106
yybR
putative transcriptional regulator [Baci...
125
other biological interest /
YybR belongs to the MarR/DUF24 family of transcriptional regulators that are hig...
Community Requests
4A5M
100%
Bacillus subtilis
IDP91209
(
show subtarget assignments
)
8
expressed
No
BT_2084
29347494
chorismate synthase [Bacteroides thetaio...
358
potential drug target /
Shikimate pathway enzyme
Community Requests
1R52
47.9%
Bacteroides thetaiotaomicron
IDP91205
(
show subtarget assignments
)
8
soluble
No
BT_3975
29349383
3-dehydroquinate synthase [Bacteroides t...
353
potential drug target /
Shikimate pathway enzyme
Community Requests
3CLH
34.3%
Bacteroides thetaiotaomicron
IDP91206
(
show subtarget assignments
)
8
in_pdb
3VAA
No
BT_3393
29348802
shikimate kinase [Bacteroides thetaiotao...
175
potential drug target /
Shikimate pathway enzyme
Community Requests
3VAA
100%
Bacteroides thetaiotaomicron
IDP91204
(
show subtarget assignments
)
8
cloned
No
BT_4215
29349623
shikimate 5-dehydrogenase [Bacteroides t...
248
potential drug target /
Shikimate pathway enzyme
Community Requests
2HK7
38%
Bacteroides thetaiotaomicron
IDP91207
(
show subtarget assignments
)
8
soluble
No
BT_2842
29348251
3-dehydroquinate dehydratase [Bacteroide...
140
potential drug target /
Shikimate pathway enzyme
Community Requests
2C4W
49%
Bacteroides thetaiotaomicron
IDP91208
(
show subtarget assignments
)
8
purified
No
BT_2186
29347596
3-phosphoshikimate 1-carboxyvinyltransfe...
410
potential drug target /
Shikimate pathway enzyme
Community Requests
1EPS
36.2%
Bacteroides thetaiotaomicron
IDP91202
(
show subtarget assignments
)
8
in_pdb
3U80
No
BLD_0610
189439473
aroQ
3-dehydroquinate dehydratase [Bifidobact...
148
potential drug target /
Shikimate pathway enzyme
Community Requests
3U80
100%
Bifidobacterium longum
IDP91212
(
show subtarget assignments
)
8
cloned
No
BLIJ_1793
189439586
aroA
3-phosphoshikimate 1-carboxyvinyltransfe...
445
potential drug target /
Shikimate pathway enzyme
Community Requests
2BJB
44.9%
Bifidobacterium longum
IDP91211
(
show subtarget assignments
)
8
purified
No
BLIJ_0365
189439940
aroG1
phospho-2-dehydro-3-deoxyheptonate aldol...
410
potential drug target /
Shikimate pathway enzyme
Community Requests
1HFB
44.1%
Bifidobacterium longum
IDP91213
(
show subtarget assignments
)
8
in_pdb
4ECD
No
Blon_1598
189439475
aroC
chorismate synthase [Bifidobacterium lon...
395
potential drug target /
Shikimate pathway enzyme
Community Requests
4ECD
100%
Bifidobacterium longum
IDP91210
(
show subtarget assignments
)
8
expressed
No
BLIJ_0364
189439941
aroG2
phospho-2-dehydro-3-deoxyheptonate aldol...
377
potential drug target /
Shikimate pathway enzyme
Community Requests
1GG1
47.7%
Bifidobacterium longum
IDP91214
(
show subtarget assignments
)
8
expressed
No
Blon_1597
189439474
aroB
bifunctional shikimate kinase/3-dehydroq...
540
potential drug target /
Shikimate pathway enzyme
Community Requests
3QBD
32.6%
Bifidobacterium longum
IDP91203
(
show subtarget assignments
)
8
cloned
No
BLD_0429
189439292
aroE
Shikimate 5-dehydrogenase [Bifidobacteri...
323
potential drug target /
Shikimate pathway enzyme
Community Requests
1WXD
26%
Bifidobacterium longum
IDP90946
(
show subtarget assignments
)
8
cloned
No
BP1878
33592926
bvgA
virulence factors transcription regulato...
209
BvgA is the transcriptional activator for all known virulence genes in the human...
Community Requests
3C3W
31.6%
Bordetella pertussis
IDP90302
(
show subtarget assignments
)
0
work_stopped
No
BB_0420
2688313
sensory transduction histidine kinase, p...
1494
Mutational studies suggest that Hk1 is required for the survival of the Lyme dis...
Community Requests
3A0R
5.6%
Borrelia burgdorferi
IDP91088
(
show subtarget assignments
)
8
cloned
No
BMA_2275
52429282
kdsB
3-deoxy-D-manno-octulosonate cytidylyltr...
263
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3K8D
52.1%
Burkholderia mallei
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP91087
(
show subtarget assignments
)
8
expressed
No
BMA_3102
52427493
carbohydrate isomerase, KpsF/GutQ family...
327
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
30.9%
Burkholderia mallei
Energy metabolism: Sugars
IDP91079
(
show subtarget assignments
)
8
cloned
No
BMA0204
53725011
ABC transporter, ATP-binding/permease pr...
623
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
4AA3
32.8%
Burkholderia mallei
IDP91096
(
show subtarget assignments
)
8
soluble
No
BPSL0876
52208929
kdsB
putative 3-deoxy-manno-octulosonate cyti...
278
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3K8D
49.6%
Burkholderia pseudomallei
IDP91093
(
show subtarget assignments
)
0
work_stopped
No
BPSL0538
52208591
conserved hypothetical protein [Burkhold...
327
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
30.9%
Burkholderia pseudomallei
IDP91806
(
show subtarget assignments
)
8
selected
No
ZP_04520447
237507732
putative polyketide synthase PksJ (PKS) ...
5053
virulence/pathogenesis /
Emerging evidence suggests that natural products from pathogenic organisms are i...
Community Requests
2VSQ
5.6%
Burkholderia pseudomallei
IDP91805
(
show subtarget assignments
)
8
selected
No
GBP346_B0724
235002726
putative polyketide synthase PksL (PKS) ...
4567
virulence/pathogenesis /
Emerging evidence suggests that natural products from pathogenic organisms are i...
Community Requests
2HG4
5.4%
Burkholderia pseudomallei
IDP91804
(
show subtarget assignments
)
8
selected
No
ZP_04523236
237510521
putative polyketide synthase PksL (PKS) ...
4567
virulence/pathogenesis /
Emerging evidence suggests that natural products from pathogenic organisms are i...
Community Requests
2HG4
5.4%
Burkholderia pseudomallei
IDP05073
(
show subtarget assignments
)
1
expressed
No
Cj0562
6968026
dnaB
gamma-glutamyl phosphate reductase [Camp...
439
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2VYE
37.1%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP01860
(
show subtarget assignments
)
1
cloned
No
Cj1294
15792617
DegT family aminotransferase [Campylobac...
376
Known Predicted virulence-O-linked flagellar glycoslyation; Predicted virulence-...
Phase 3: June 2008
2FN6
44.7%
Campylobacter jejuni
Protein synthesis
tRNA aminoacylation
IDP02654
(
show subtarget assignments
)
1
cloned
No
Cj1682c
15792986
gltA
citrate synthase [Campylobacter jejuni s...
422
Possible Vaccine Candidate; Predicted Essential-Modeling
Phase 3: June 2008
2H12
50.2%
Campylobacter jejuni
Cellular processes
Chemotaxis and motility
IDP02634
(
show subtarget assignments
)
1
cloned
No
Cj1125c
15792450
wlaG
general glycosylation pathway protein [C...
376
Known Predicted virulence-N-linked protein glycoslyation; Predicted virulence-Po...
Phase 3: June 2008
2JJM
22.6%
Campylobacter jejuni
Cellular processes
Chemotaxis and motility
IDP02627
(
show subtarget assignments
)
1
soluble
No
Cj1729c
15793032
flgE
flagellar hook protein FlgE [Campylobact...
865
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
3A69
13.4%
Campylobacter jejuni
Cell envelope
Other
IDP02626
(
show subtarget assignments
)
1
cloned
No
Cj1614
15792919
chuA
TonB-dependent heme receptor [Campylobac...
709
Predicted virulence-Iron Scavenging Mechanisms; Possible Vaccine Candidate
Phase 3: June 2008
3FHH
23.3%
Campylobacter jejuni
Regulatory functions
Other
IDP02623
(
show subtarget assignments
)
1
cloned
No
Cj1430c
15792748
putative nucleotide-sugar epimerase/dehy...
181
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
1DZR
30.9%
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP02633
(
show subtarget assignments
)
1
cloned
No
Cj1431c
15792749
hypothetical protein Cj1431c [Campylobac...
582
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP01856
(
show subtarget assignments
)
1
expressed
No
Cj1152c
15792476
putative phosphatase [Campylobacter jeju...
186
Known Predicted virulence-LOS-Immune evasion and molecular mimcry; PMID:15578098...
Phase 3: June 2008
2GMW
37.1%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP01836
(
show subtarget assignments
)
1
cloned
No
Cj1659
15792963
p19
hypothetical protein Cj1659 [Campylobact...
179
Predicted virulence-Iron Scavenging Mechanisms
Phase 3: June 2008
3LZL
88.3%
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP02599
(
show subtarget assignments
)
1
cloned
No
Cj1138
15792463
putative galactosyltransferase [Campylob...
389
Known Predicted virulence-LOS-Immune evasion and molecular mimcry; PMID:15578098...
Phase 3: June 2008
3L7I
22%
Campylobacter jejuni
Energy metabolism
Sugars
IDP02598
(
show subtarget assignments
)
1
cloned
No
Cj1429c
15792747
hypothetical protein Cj1429c [Campylobac...
308
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP02602
(
show subtarget assignments
)
1
cloned
No
Cj1148
15792472
waaF
ADP-heptose--LPS heptosyltransferase II ...
319
Known Predicted virulence-LOS-Immune evasion and molecular mimcry; PMID:15578098...
Phase 3: June 2008
1PSW
24.7%
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP02610
(
show subtarget assignments
)
1
expressed
No
Cj1417c
15792735
hypothetical protein Cj1417c [Campylobac...
200
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
1GEE
87.7%
Campylobacter jejuni
Cell envelope
Other
IDP02586
(
show subtarget assignments
)
1
cloned
No
Cj1478c
15792793
cadF
fibronectin-binding protein [Campylobact...
319
Known Predicted virulence-adherence; Predicted virulence-Adhesion of Campylobact...
Phase 3: June 2008
3NB3
24.5%
Campylobacter jejuni
Cell envelope
Other
IDP02579
(
show subtarget assignments
)
1
cloned
No
Cj1131c
15792456
galE
UDP-glucose 4-epimerase [Campylobacter j...
328
Predicted virulence-Posttranslational modification
Phase 3: June 2008
2C20
41.5%
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP02582
(
show subtarget assignments
)
1
soluble
No
Cj1349c
15792672
fibronectin/fibrinogen-binding protein [...
435
Predicted virulence-Adhesion of Campylobacter
Phase 3: June 2008
3DOA
10.6%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP01827
(
show subtarget assignments
)
1
expressed
No
Cj0526c
15791887
fliE
flagellar hook-basal body protein FliE [...
98
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP02571
(
show subtarget assignments
)
1
expressed
No
Cj0549
15791910
fliS
flagellar protein FliS [Campylobacter je...
128
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
3IQC
58.6%
Campylobacter jejuni
Cell envelope
Other
IDP02567
(
show subtarget assignments
)
1
cloned
No
Cj1414c
15792732
polysaccharide modification protein [Cam...
689
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
Campylobacter jejuni
Central intermediary metabolism
Other
IDP02570
(
show subtarget assignments
)
1
cloned
No
Cj1339c
15792662
flaA
flagellin [Campylobacter jejuni subsp. j...
572
Known Predicted virulence-flagella; Possible Vaccine Candidate; PMID:8478066
Phase 3: June 2008
1UCU
28%
Campylobacter jejuni
Cell envelope
Surface structures
IDP02754
(
show subtarget assignments
)
1
expressed
No
Cj0527c
15791888
flgC
flagellar basal body rod protein FlgC [C...
164
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP02553
(
show subtarget assignments
)
1
cloned
No
Cj1293
15792616
polysaccharide biosynthesis protein [Cam...
334
Known Predicted virulence-O-linked flagellar glycoslyation; Predicted virulence-...
Phase 3: June 2008
2GN4
63.5%
Campylobacter jejuni
Energy metabolism
Glycolysis/gluconeogenesis
IDP02557
(
show subtarget assignments
)
1
purified
No
Cj0061c
15791453
fliA
flagellar biosynthesis sigma factor [Cam...
238
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
1RP3
35.3%
Campylobacter jejuni
Cellular processes
Chemotaxis and motility
IDP02546
(
show subtarget assignments
)
1
expressed
No
Cj1143
15792468
neuA1
acylneuraminate cytidylyltransferase [Ca...
536
Known Predicted virulence-LOS-Immune evasion and molecular mimcry; Predicted Ess...
Phase 3: June 2008
1EYR
16.2%
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP02547
(
show subtarget assignments
)
0
work_stopped
No
Cj1316c
15792639
flagellin modification protein, PseA [Ca...
378
Known Predicted virulence-O-linked flagellar glycoslyation; Predicted virulence-...
Phase 3: June 2008
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP02548
(
show subtarget assignments
)
1
cloned
No
Cj0861c
15792199
pabA
para-aminobenzoate synthase glutamine am...
188
Possible Vaccine Candidate; Predicted Essential-Modeling
Phase 3: June 2008
1QDL
44%
Campylobacter jejuni
Cell envelope
Other
IDP02544
(
show subtarget assignments
)
1
cloned
No
Cj1142
15792467
neuC1
putative N-acetylglucosamine-6-phosphate...
371
Known Predicted virulence-LOS-Immune evasion and molecular mimcry; Predicted Ess...
Phase 3: June 2008
3OT5
21.6%
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
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