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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 11 of 60, showing 100 records out of 5973 total, starting on record 1001
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP05165
(
show subtarget assignments
)
1
soluble
No
BA_1888
30256549
enterotoxin [Bacillus anthracis str. Ame...
402
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2NRJ
24.6%
Bacillus anthracis
Cellular processes: Pathogenesis
IDP05064
(
show subtarget assignments
)
1
cloned
No
CD2370
126699985
nadC
nicotinate-nucleotide pyrophosphorylase ...
270
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1X1O
46.7%
Clostridium difficile
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
IDP04071
(
show subtarget assignments
)
1
cloned
No
BAS0129
49183163
50S ribosomal protein L15 [Bacillus anth...
146
Proposed to be essential proteins
Phase 4: April 2009
1VSA
51.4%
Bacillus anthracis
IDP05116
(
show subtarget assignments
)
1
soluble
No
CD2542
126700159
hypothetical protein CD2542 [Clostridium...
402
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP05417
(
show subtarget assignments
)
1
purified
No
BA_4788
30259274
conserved domain protein [Bacillus anthr...
152
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3SIK
82.9%
Bacillus anthracis
Hypothetical proteins: Domain
IDP05296
(
show subtarget assignments
)
1
purified
No
CD2138
126699755
pyrH
uridylate kinase [Clostridium difficile ...
234
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1Z9D
59.1%
Clostridium difficile
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
IDP04612
(
show subtarget assignments
)
1
cloned
No
BAS3764
49186763
phospho-N-acetylmuramoyl-pentapeptide-tr...
324
Proposed to be essential proteins
Phase 4: April 2009
Bacillus anthracis
IDP04578
(
show subtarget assignments
)
1
cloned
No
BAS0089
49183123
cysteinyl-tRNA synthetase [Bacillus anth...
465
Proposed to be essential proteins
Phase 4: April 2009
1LI5
45.6%
Bacillus anthracis
IDP04080
(
show subtarget assignments
)
1
cloned
No
BAS0123
49183157
30S ribosomal protein S14 [Bacillus anth...
61
Proposed to be essential proteins
Phase 4: April 2009
1FJG
73.8%
Bacillus anthracis
IDP05162
(
show subtarget assignments
)
1
soluble
No
BA_1701
30255991
hypothetical protein BA_1701 [Bacillus a...
225
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04586
(
show subtarget assignments
)
1
cloned
No
BAS0117
49183151
50S ribosomal protein L16 [Bacillus anth...
144
Proposed to be essential proteins
Phase 4: April 2009
1VSA
60.4%
Bacillus anthracis
IDP04579
(
show subtarget assignments
)
1
cloned
No
BAS0098
49183132
50S ribosomal protein L1 [Bacillus anthr...
230
Proposed to be essential proteins
Phase 4: April 2009
3QOY
56.3%
Bacillus anthracis
IDP04580
(
show subtarget assignments
)
1
cloned
No
BAS0103
49183137
DNA-directed RNA polymerase subunit beta...
1203
Proposed to be essential proteins
Phase 4: April 2009
2GHO
53.6%
Bacillus anthracis
IDP04075
(
show subtarget assignments
)
8
selected
No
CAC05807
12329076
icsB
IcsB, function unknown [Shigella flexner...
494
Shigella effector protein
Community Requests
Shigella flexneri
IDP04079
(
show subtarget assignments
)
1
purified
No
BAS0100
49183134
50S ribosomal protein L7/L12 [Bacillus a...
119
Proposed to be essential proteins
Phase 4: April 2009
1DD3
63.3%
Bacillus anthracis
IDP05454
(
show subtarget assignments
)
1
purified
No
BA_0190
30253697
putative lipoprotein [Bacillus anthracis...
155
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP04582
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0110
49183144
50S ribosomal protein L3 [Bacillus anthr...
210
Proposed to be essential proteins
Phase 4: April 2009
1NKW
53.3%
Bacillus anthracis
IDP04581
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0108
49183142
elongation factor Tu [Bacillus anthracis...
395
Proposed to be essential proteins
Phase 4: April 2009
3U2Q
75.4%
Bacillus anthracis
IDP04077
(
show subtarget assignments
)
1
crystallized
No
FTT1793c
56708781
pepN
aminopeptidase N [Francisella tularensis...
864
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
2DQ6
48.9%
Francisella tularensis
IDP04583
(
show subtarget assignments
)
1
cloned
No
BAS0111
49183145
50S ribosomal protein L4 [Bacillus anthr...
207
Proposed to be essential proteins
Phase 4: April 2009
1DMG
47.1%
Bacillus anthracis
IDP05244
(
show subtarget assignments
)
1
soluble
No
lmo2203
16804242
-
hypothetical protein lmo2203 [Listeria m...
367
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1M9S
22.6%
Listeria monocytogenes
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP04584
(
show subtarget assignments
)
1
purified
No
BAS0112
49183146
50S ribosomal protein L23 [Bacillus anth...
96
Proposed to be essential proteins
Phase 4: April 2009
1N88
43.8%
Bacillus anthracis
IDP05079
(
show subtarget assignments
)
1
cloned
No
lmo1438
16803478
-
hypothetical protein lmo1438 [Listeria m...
721
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2WAE
32.6%
Listeria monocytogenes
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP05190
(
show subtarget assignments
)
1
cloned
No
CD0248
126697819
fliF
flagellar MS-ring protein [Clostridium d...
516
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05025
(
show subtarget assignments
)
1
cloned
No
BAS4742
49187733
-
hypothetical protein BAS4742 [Bacillus a...
200
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Hypothetical proteins: Conserved
IDP04025
(
show subtarget assignments
)
1
expressed
No
YPCD1.36c
16082724
yscX
hypothetical protein YPCD1.36c [Yersinia...
122
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP05463
(
show subtarget assignments
)
1
soluble
No
BA_1288
30255236
spore coat-associated protein [Bacillus ...
195
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05576
(
show subtarget assignments
)
1
cloned
No
BA_0536
30254062
bcP
bacterioferritin comigratory protein [Ba...
151
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3DRN
41.7%
Bacillus anthracis
Cellular processes: Detoxification
IDP04028
(
show subtarget assignments
)
1
purified
No
BAS0109
49183143
30S ribosomal protein S10 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1P6G
61.8%
Bacillus anthracis
IDP04115
(
show subtarget assignments
)
1
expressed
No
STM2352_1_235
16765679
hisM
histidine/lysine/arginine/ornithine tran...
235
Salmonella essential protein
Phase 4: April 2009
3DHW
23.8%
Salmonella enterica
IDP05217
(
show subtarget assignments
)
1
in_crystallization_trials
No
CD3421
126701044
hemC
porphobilinogen deaminase [Clostridium d...
301
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1PDA
37.2%
Clostridium difficile
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
IDP04045
(
show subtarget assignments
)
1
soluble
No
FTT1747
56708745
outer membrane protein [Francisella tula...
191
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Francisella tularensis
IDP05358
(
show subtarget assignments
)
1
cloned
No
BA_0685
30254284
conserved hypothetical protein [Bacillus...
420
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1I84
12.1%
Bacillus anthracis
Hypothetical proteins: Conserved
IDP04617
(
show subtarget assignments
)
1
expressed
No
BAS4342
49187337
50S ribosomal protein L21 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1VSA
54.9%
Bacillus anthracis
IDP05012
(
show subtarget assignments
)
1
cloned
No
BA_5070
30259559
cell wall surface anchor family protein ...
148
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05019
(
show subtarget assignments
)
1
expressed
No
CD0267
126697839
hypothetical protein CD0267 [Clostridium...
145
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP04601
(
show subtarget assignments
)
1
in_pdb
3RHI
Yes
BAS3574
49186575
DNA-binding protein HU [Bacillus anthrac...
90
Proposed to be essential proteins
Phase 4: April 2009
3RHI
100%
Bacillus anthracis
IDP05069
(
show subtarget assignments
)
1
cloned
No
CD2789
126700405
cwp66
cell surface protein [Clostridium diffic...
610
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP04599
(
show subtarget assignments
)
1
cloned
No
BAS2268
49185277
aspartate-semialdehyde dehydrogenase [Ba...
347
Proposed to be essential proteins
Phase 4: April 2009
2GYY
55.3%
Bacillus anthracis
IDP04119
(
show subtarget assignments
)
1
crystallized
No
BAS0131
49183165
adenylate kinase [Bacillus anthracis str...
216
Proposed to be essential proteins
Phase 4: April 2009
1ZIN
74.1%
Bacillus anthracis
IDP05193
(
show subtarget assignments
)
1
cloned
No
CD0689
126698268
putative nucleotide phosphodiesterase [C...
627
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3GVE
16.4%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP04003
(
show subtarget assignments
)
1
cloned
No
BAS0126
49183160
50S ribosomal protein L18 [Bacillus anth...
120
Proposed to be essential proteins
Phase 4: April 2009
1OVY
75.8%
Bacillus anthracis
IDP04120
(
show subtarget assignments
)
1
soluble
No
BAS1475
49184492
xanthine phosphoribosyltransferase [Baci...
197
Proposed to be essential proteins
Phase 4: April 2009
1Y0B
65%
Bacillus anthracis
IDP05068
(
show subtarget assignments
)
1
soluble
No
CD2735
126700350
cell surface protein [Clostridium diffic...
475
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2KQ8
5.5%
Clostridium difficile
Cell envelope: Other
IDP05042
(
show subtarget assignments
)
1
soluble
No
BA_2921
30257513
putative sulfonate ABC transporter, sulf...
328
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2X26
28%
Bacillus anthracis
Transport and binding proteins: Anions
IDP05075
(
show subtarget assignments
)
1
cloned
No
lmo0466
16802510
-
hypothetical protein lmo0466 [Listeria m...
576
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
Listeria monocytogenes
DNA metabolism: DNA replication, recombination, and repair
IDP04117
(
show subtarget assignments
)
8
selected
No
CAC05825
12329094
spa13
spa13, component of the Mxi-Spa secretio...
112
Shigella effector protein
Community Requests
Shigella flexneri
IDP05607
(
show subtarget assignments
)
1
soluble
No
BA_4862
30259361
putative lipoprotein [Bacillus anthracis...
123
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2JQO
23.6%
Bacillus anthracis
Cell envelope: Other
IDP04024
(
show subtarget assignments
)
1
cloned
No
BAS5319
49188303
DNA-binding response regulator YycF [Bac...
235
Proposed to be essential proteins
Phase 4: April 2009
2OQR
47.7%
Bacillus anthracis
IDP05327
(
show subtarget assignments
)
1
cloned
No
lmo1504
16803544
alaS
alanyl-tRNA synthetase [Listeria monocyt...
879
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1RIQ
25.8%
Listeria monocytogenes
Protein synthesis: tRNA aminoacylation
IDP04116
(
show subtarget assignments
)
1
expressed
No
Z5122
15804232
sepZ
hypothetical protein Z5122 [Escherichia ...
99
Effector protein
Phase 4: April 2009
Escherichia coli
IDP05088
(
show subtarget assignments
)
1
cloned
No
BA_0871
30254621
LPXTG-motif cell wall anchor domain prot...
969
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3KPT
10.8%
Bacillus anthracis
Cell envelope: Other
IDP91010
(
show subtarget assignments
)
8
cloned
No
y2245
22126131
hypothetical protein y2245 [Yersinia pes...
341
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3ETN
12.3%
Yersinia pestis
IDP91011
(
show subtarget assignments
)
8
purified
No
y2255
22126141
hypothetical protein y2255 [Yersinia pes...
251
other biological interest /
possibly involved in quorum sensing
Community Requests
1KON
83.3%
Yersinia pestis
IDP05509
(
show subtarget assignments
)
1
expressed
No
BA_5736
30260182
spoIIIJ2
stage III sporulation protein J [Bacillu...
255
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05615
(
show subtarget assignments
)
1
soluble
No
BA_5522
30259982
putative lipoprotein [Bacillus anthracis...
126
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05743
(
show subtarget assignments
)
1
cloned
No
CD2653
126700267
murD
UDP-N-acetylmuramoylalanine--D-glutamate...
451
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3LK7
38.9%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP05763
(
show subtarget assignments
)
1
cloned
No
lmo2331
16804370
-
hypothetical protein lmo2331 [Listeria m...
226
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05003
(
show subtarget assignments
)
1
cloned
No
BA_3309
30257855
hypothetical protein BA_3309 [Bacillus a...
31
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05144
(
show subtarget assignments
)
1
soluble
No
BAS4556
49187550
-
tyrosyl-tRNA synthetase [Bacillus anthra...
418
Known drug target or ortholog of known drug target
Phase 5: 2010
2TS1
70.6%
Bacillus anthracis
Protein synthesis: tRNA aminoacylation
IDP05298
(
show subtarget assignments
)
1
purified
No
CD2189
126699805
pgmB
beta-phosphoglucomutase [Clostridium dif...
226
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3NAS
46.9%
Clostridium difficile
Energy metabolism: Biosynthesis and degradation of polysaccharides
IDP05469
(
show subtarget assignments
)
1
soluble
No
BA_2398
30257029
putative lipoprotein [Bacillus anthracis...
177
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05353
(
show subtarget assignments
)
1
cloned
No
CD2903
126700520
putative phage cell wall hydrolase [Clos...
656
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3H41
8.1%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP04027
(
show subtarget assignments
)
1
cloned
No
BAS4637
49187628
leucyl-tRNA synthetase [Bacillus anthrac...
802
Proposed to be essential proteins
Phase 4: April 2009
1H3N
45.9%
Bacillus anthracis
IDP04616
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS4313
49187308
S-adenosylmethionine:tRNA ribosyltransfe...
350
Proposed to be essential proteins
Phase 4: April 2009
1YY3
71.4%
Bacillus anthracis
IDP05074
(
show subtarget assignments
)
1
cloned
No
lmo0135
16802183
-
hypothetical protein lmo0135 [Listeria m...
524
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1XOC
32.4%
Listeria monocytogenes
Transport and binding proteins: Amino acids, peptides and amines
IDP05011
(
show subtarget assignments
)
1
soluble
No
BA_4970
30259463
hypothetical protein BA_4970 [Bacillus a...
139
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04621
(
show subtarget assignments
)
1
cloned
No
BAS4494
49187489
acetyl-CoA carboxylase carboxyltransfera...
324
Proposed to be essential proteins
Phase 4: April 2009
2F9I
60.2%
Bacillus anthracis
IDP05071
(
show subtarget assignments
)
1
cloned
No
CD3291
126700910
hypothetical protein CD3291 [Clostridium...
174
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP05070
(
show subtarget assignments
)
1
cloned
No
CD3246
126700865
putative surface protein [Clostridium di...
709
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Surface structures
IDP05072
(
show subtarget assignments
)
1
cloned
No
CD3564
126701190
spoIIR
stage II sporulation protein [Clostridiu...
198
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cellular processes: Sporulation and germination
IDP04026
(
show subtarget assignments
)
1
expressed
No
FTT0456c
56707598
hypothetical protein FTT_0456c [Francise...
97
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1YHD
39.2%
Francisella tularensis
IDP05126
(
show subtarget assignments
)
1
expressed
No
BA_4346
30258846
cpdB
2',3'-cyclic-nucleotide 2'-phosphodieste...
774
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3JYF
20.7%
Bacillus anthracis
Purines, pyrimidines, nucleosides, and nucleotides: Other
IDP05188
(
show subtarget assignments
)
1
purified
No
CD0235
126697806
fliS1
flagellar protein FliS [Clostridium diff...
131
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1VH6
29.8%
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05010
(
show subtarget assignments
)
1
soluble
No
BA_4934
30259430
putative lipoprotein [Bacillus anthracis...
144
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP04605
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS3689
49186688
ribosomal biogenesis GTPase [Bacillus an...
296
Proposed to be essential proteins
Phase 4: April 2009
1PUJ
67.2%
Bacillus anthracis
IDP05186
(
show subtarget assignments
)
1
cloned
No
CD0120
126697692
glmS
glucosamine--fructose-6-phosphate aminot...
610
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1JXA
47.1%
Clostridium difficile
Central intermediary metabolism: Amino sugars
IDP05178
(
show subtarget assignments
)
1
expressed
No
BA_3332
30257877
putative S-layer protein [Bacillus anthr...
338
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
15.1%
Bacillus anthracis
Cell envelope: Surface structures
IDP04135
(
show subtarget assignments
)
1
cloned
No
BAS4470
49187465
50S ribosomal protein L35 [Bacillus anth...
66
Proposed to be essential proteins
Phase 4: April 2009
1VS6
48.5%
Bacillus anthracis
IDP05009
(
show subtarget assignments
)
1
soluble
No
BA_4237
30258740
putative lipoprotein [Bacillus anthracis...
253
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05073
(
show subtarget assignments
)
1
expressed
No
Cj0562
6968026
dnaB
gamma-glutamyl phosphate reductase [Camp...
439
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2VYE
37.1%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP05004
(
show subtarget assignments
)
1
cloned
No
CDP01
110666923
hypothetical protein CDP01 [Clostridium ...
33
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP05008
(
show subtarget assignments
)
1
cloned
No
CD1777
126699386
putative arsenate reductase [Clostridium...
120
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3FZ4
41.7%
Clostridium difficile
Cellular processes: Detoxification
IDP05005
(
show subtarget assignments
)
1
cloned
No
CDP11
110666933
hypothetical protein CDP11 [Clostridium ...
33
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Hypothetical proteins: Conserved
IDP04137
(
show subtarget assignments
)
1
soluble
No
BAS0134
49183168
50S ribosomal protein L36 [Bacillus anth...
37
Proposed to be essential proteins
Phase 4: April 2009
1DFE
81.1%
Bacillus anthracis
IDP05006
(
show subtarget assignments
)
1
cloned
No
BA_3083
30257668
putative lipoprotein [Bacillus anthracis...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05078
(
show subtarget assignments
)
1
soluble
No
lmo1340
16803380
-
hypothetical protein lmo1340 [Listeria m...
363
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Transport and binding proteins: Unknown substrate
IDP04038
(
show subtarget assignments
)
1
expressed
No
YPCD1.65
5832485
YPCD1.65
putative transposase [Yersinia pestis CO...
102
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP05249
(
show subtarget assignments
)
1
soluble
No
BAS2289
49185298
-
hypothetical protein BAS2289 [Bacillus a...
512
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05326
(
show subtarget assignments
)
1
cloned
No
CD3562
126701188
murI
glutamate racemase [Clostridium difficil...
268
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3OUT
45.2%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP05076
(
show subtarget assignments
)
1
soluble
No
lmo0801
16802843
-
hypothetical protein lmo0801 [Listeria m...
646
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1M9S
22.1%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05016
(
show subtarget assignments
)
1
soluble
No
BA_2056
30256706
putative lipoprotein [Bacillus anthracis...
59
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP04598
(
show subtarget assignments
)
1
cloned
No
BAS1442
49184459
dihydrodipicolinate reductase [Bacillus ...
266
Proposed to be essential proteins
Phase 4: April 2009
1C3V
40.6%
Bacillus anthracis
IDP04035
(
show subtarget assignments
)
1
in_pdb
3P0R
Yes
BAS5262
49188247
azoreductase [Bacillus anthracis str. St...
208
Proposed to be essential proteins
Phase 4: April 2009
3P0R
100%
Bacillus anthracis
IDP04034
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0128
49183162
50S ribosomal protein L30 [Bacillus anth...
60
Proposed to be essential proteins
Phase 4: April 2009
1VS6
53.3%
Bacillus anthracis
IDP05015
(
show subtarget assignments
)
1
cloned
No
CD0247
126697818
fliE
flagellar hook-basal body protein FliE [...
105
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP04597
(
show subtarget assignments
)
1
expressed
No
BAS1384
49184401
resB protein [Bacillus anthracis str. St...
541
Proposed to be essential proteins
Phase 4: April 2009
Bacillus anthracis
IDP05364
(
show subtarget assignments
)
1
soluble
No
BA_2881
30257478
bacterial extracellular solute-binding p...
578
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3M8U
19.2%
Bacillus anthracis
Transport and binding proteins: Unknown substrate
IDP91143
(
show subtarget assignments
)
8
in_pdb
3R2T
Yes
SAOUHSC_00393
88194188
superantigen-like protein [Staphylococcu...
232
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3R2T
100%
Staphylococcus aureus
IDP91106
(
show subtarget assignments
)
8
in_pdb
3QFK
Yes
SAOUHSC_00107
88193920
hypothetical protein SAOUHSC_00107 [Stap...
511
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3QFK
99.8%
Staphylococcus aureus
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