(skip to main content)
Home
Target List
Selection
Community Requests
Clones
Screenings
XML files
Diffraction Images
Progress
Homolog Search
Clustering
Statistics
News
Help
Log In
Consortium
Overview
Investigators
Experiments
X-ray Structures
NMR Structures
Electronic Structure Description
Publications
Resources
Clustering
Related Sites
Progress
Collaborators
Basecamp
Contact Us
Log In
Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
In
IDP#
NCBI GI
LOCUS TAG
Search
Page 11 of 60, showing 100 records out of 5973 total, starting on record 1001
previous
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
20
|
next
CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP01148
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_1159
30254878
katB
catalase
488
Conserved Gene / Pathway
Phase 2: March 2008
2J2M
64.8%
Bacillus anthracis
Cellular processes
Detoxification
IDP90786
(
show subtarget assignments
)
8
cloned
No
Cj1385
15792708
katA
catalase [Campylobacter jejuni subsp. je...
474
Predicted Essential
Community Requests
2ISA
57.8%
Campylobacter jejuni
IDP90983
(
show subtarget assignments
)
8
selected
No
y0870
22124781
katG
catalase-peroxidase [Yersinia pestis KIM...
751
virulence/pathogenesis /
stress response protein and antigen in Y pestis
Community Requests
2FXG
59.4%
Yersinia pestis
IDP91939
(
show subtarget assignments
)
8
selected
No
SpneCM_010100003755
298254716
cation diffusion facilitator transporter...
296
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2QFI
15.9%
Streptococcus pneumoniae
IDP00859
(
show subtarget assignments
)
1
soluble
No
STM1770
16765111
chaB
cation transport regulator
76
Conserved Gene / Pathway
Phase 2: March 2008
1SG7
81.6%
Salmonella enterica
Transport and binding proteins
Unknown substrate
IDP02609
(
show subtarget assignments
)
1
in_pdb
3LQN
Yes
GBAA4196
47529491
CBS domain-containing protein [Bacillus ...
147
Drug target motif;
Phase 3: June 2008
3LQN
100%
Bacillus anthracis
Unknown function
General
IDP01960
(
show subtarget assignments
)
1
soluble
No
CBU_0565
29541166
CBS domain protein [Coxiella burnetii RS...
279
Conserved; Drug target functions
Phase 3: June 2008
3LFR
27.2%
Coxiella burnetii
Unknown function
General
IDP00763
(
show subtarget assignments
)
1
expressed
No
SACOL0262
57286722
Ccholoylglycine hydrolase family protein...
330
Conserved Gene / Pathway
Phase 2: March 2008
2OQC
32.4%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP91661
(
show subtarget assignments
)
8
selected
No
NP_002980
4506835
CCL21
C-C motif chemokine 21 precursor [Homo s...
134
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2L4N
82.8%
Homo sapiens
IDP91708
(
show subtarget assignments
)
8
selected
No
NP_005615
22538796
CCL25
C-C motif chemokine 25 isoform 1 precurs...
150
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2L4N
18.7%
Homo sapiens
IDP91730
(
show subtarget assignments
)
8
selected
No
NP_683513
22538811
CCL28
C-C motif chemokine 28 precursor [Homo s...
127
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2KUM
22.8%
Homo sapiens
IDP90133
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_159
68449233
CD47-like putative membrane protein [Mon...
277
similar to VACV-COP-A38L, MPXV-ZAI96-A40L
Community Requests
2JJS
11.6%
Monkeypox virus
IDP05231
(
show subtarget assignments
)
1
purified
No
lmo1388
16803428
tcsA
CD4+ T cell-stimulating antigen, lipopro...
346
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2FQW
39.9%
Listeria monocytogenes
Unclassified: Role category not yet assigned
IDP90960
(
show subtarget assignments
)
8
expressed
No
VC0658
81545351
C-di-GMP phosphodiesterase A-related pro...
685
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
18.7%
Vibrio cholerae
IDP90963
(
show subtarget assignments
)
8
cloned
No
VP2446
81727013
C-di-GMP phosphodiesterase A-related pro...
679
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
15.5%
Vibrio parahaemolyticus
IDP90951
(
show subtarget assignments
)
8
purified
No
VC0653
81545356
C-di-GMP phosphodiesterase A-related pro...
684
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
15.5%
Vibrio cholerae
IDP04140
(
show subtarget assignments
)
1
cloned
No
YPO3116
115348760
ascD
cdp-6-deoxy-delta-3,4-glucoseen reductas...
329
virulence factor; putative drug target function;
Phase 4: April 2009
1KRH
26.4%
Yersinia pestis
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP01847
(
show subtarget assignments
)
1
soluble
No
GBAA5416
47530729
ftsE
cell division ABC transporter, ATP-bindi...
214
Conserved; Drug target functions
Phase 3: June 2008
3DHW
41.1%
Bacillus anthracis
Cellular processes
Cell division
IDP02371
(
show subtarget assignments
)
1
expressed
No
CBU_1904
29542461
ftsE
cell division ABC transporter, ATP-bindi...
217
Conserved; Drug target functions
Phase 3: June 2008
1F3O
38.1%
Coxiella burnetii
Transport and binding proteins
Unknown substrate
IDP91938
(
show subtarget assignments
)
8
selected
No
SpneCM_010100009513
298255813
cell division ABC transporter, permease ...
308
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP01360
(
show subtarget assignments
)
1
purified
No
VC0148
15640179
cell division ATP-binding protein FtsE
233
Conserved Gene / Pathway
Phase 2: March 2008
2PCJ
35.6%
Vibrio cholerae
Cellular processes
Cell division
IDP00588
(
show subtarget assignments
)
1
purified
No
YPO2077
16122316
minD
cell division inhibitor MinD
270
Conserved Gene / Pathway
Phase 2: March 2008
3Q9L
87.8%
Yersinia pestis
Cellular processes
Cell division
IDP00975
(
show subtarget assignments
)
1
cloned
No
STM1815
16765156
minD
cell division inhibitor MinD
270
Conserved Gene / Pathway
Phase 2: March 2008
3Q9L
93.3%
Salmonella enterica
Cellular processes
Cell division
IDP00549
(
show subtarget assignments
)
1
purified
No
YPO3814
16123948
ftsY
cell division protein
541
Conserved Gene / Pathway
Phase 2: March 2008
2YHS
63.7%
Yersinia pestis
Cellular processes
Cell division
IDP91907
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004287
298254820
cell division protein DivIB [Streptococc...
406
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP00714
(
show subtarget assignments
)
1
cloned
No
SACOL1198
57285941
ftsA
cell division protein FtsA
470
Drug Target Function
Phase 2: March 2008
1E4F
18.3%
Staphylococcus aureus
Cellular processes
Cell division
IDP02788
(
show subtarget assignments
)
1
expressed
No
CBU_0140
29540760
ftsA
cell division protein FtsA [Coxiella bur...
410
Conserved; Drug target functions
Phase 3: June 2008
1E4F
22.9%
Coxiella burnetii
Cellular processes
Cell division
IDP02098
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT0187
56707352
ftsA
cell division protein FtsA [Francisella ...
420
Conserved; Drug target functions
Phase 3: June 2008
1E4F
24%
Francisella tularensis
Cellular processes
Cell division
IDP00547
(
show subtarget assignments
)
1
expressed
No
YPO3813
16123947
ftsE
cell division protein FtsE
222
Conserved Gene / Pathway
Phase 2: March 2008
3DHW
39.6%
Yersinia pestis
Cellular processes
Cell division
IDP00865
(
show subtarget assignments
)
1
expressed
No
STM3570
16766856
ftsE
cell division protein FtsE
222
Conserved Gene / Pathway
Phase 2: March 2008
3DHW
41.9%
Salmonella enterica
Cellular processes
Cell division
IDP00410
(
show subtarget assignments
)
1
cloned
No
YPO0548
16120876
ftsL
cell division protein FtsL
105
Conserved Gene / Pathway
Phase 2: March 2008
Yersinia pestis
Cellular processes
Cell division
IDP00473
(
show subtarget assignments
)
1
cloned
No
YPO0107
16120454
ftsN
cell division protein FtsN
281
Conserved Gene / Pathway
Phase 2: March 2008
1UTA
15.3%
Yersinia pestis
Cellular processes
Cell division
IDP05496
(
show subtarget assignments
)
1
soluble
No
BA_4047
30258554
cell division protein FtsQ [Bacillus ant...
265
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1YR1
15.5%
Bacillus anthracis
Cellular processes: Cell division
IDP04020
(
show subtarget assignments
)
1
cloned
No
CPF_2112
110800515
cell division protein FtsQ [Clostridium ...
248
conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cellular processes
Cell division
IDP01359
(
show subtarget assignments
)
1
soluble
No
VC0147
15640178
cell division protein FtsY
391
Conserved Gene / Pathway
Phase 2: March 2008
2YHS
67.5%
Vibrio cholerae
Protein fate
Protein and peptide secretion and trafficking
IDP01122
(
show subtarget assignments
)
1
soluble
No
BA_4045
30258552
ftsZ
cell division protein FtsZ
386
Conserved Gene / Pathway
Phase 2: March 2008
2VAM
78.1%
Bacillus anthracis
Cellular processes
Cell division
IDP01339
(
show subtarget assignments
)
1
purified
No
VC2397
15642394
cell division protein FtsZ
398
Conserved Gene / Pathway
Phase 2: March 2008
2VAW
58.6%
Vibrio cholerae
Cellular processes
Cell division
IDP00669
(
show subtarget assignments
)
1
cloned
No
SACOL1199
57285942
ftsZ
cell division protein FtsZ
390
Drug Target Function
Phase 2: March 2008
2VAM
68.7%
Staphylococcus aureus
Cellular processes
Cell division
IDP04259
(
show subtarget assignments
)
1
cloned
No
CPF_2018
110799691
ftsZ
cell division protein FtsZ [Clostridium ...
381
conserved gene; putative drug target function;
Phase 4: April 2009
2VAM
58%
Clostridium perfringens
Cellular processes
Cell division
IDP02789
(
show subtarget assignments
)
1
cloned
No
CBU_0141
29540761
ftsZ
cell division protein FtsZ [Coxiella bur...
386
Conserved; Drug target functions
Phase 3: June 2008
2VAW
63.4%
Coxiella burnetii
Cellular processes
Cell division
IDP02166
(
show subtarget assignments
)
1
cloned
No
FTT0188
56707353
ftsZ
cell division protein FtsZ [Francisella ...
381
Conserved; Drug target functions
Phase 3: June 2008
2VAW
55.9%
Francisella tularensis
Cellular processes
Cell division
IDP04101
(
show subtarget assignments
)
1
purified
No
CPF_2392
110799105
minE
cell division topological specificity fa...
90
conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cellular processes
Cell division
IDP02301
(
show subtarget assignments
)
1
cloned
No
FTT1249
56708311
cell entry (mce) related family protein ...
241
Drug Target
Phase 3: June 2008
Francisella tularensis
Transport and binding proteins
Unknown substrate
IDP00255
(
show subtarget assignments
)
1
selected
No
NP_041725:276-677
9627243
CFA
Cell fusing agent virus Envelope protein...
402
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3C5X
15.2%
Cell fusing
IDP91386
(
show subtarget assignments
)
8
cloned
No
VV1_1450
27364835
cell shape-determining protein [Vibrio v...
296
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
2J5U
19.3%
Vibrio vulnificus
IDP05573
(
show subtarget assignments
)
1
selected
No
BAS4798
49187788
-
cell surface protein, anchor [Bacillus a...
2025
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
DNA metabolism: DNA replication, recombination, and repair
IDP05641
(
show subtarget assignments
)
1
soluble
No
CD2799
126700415
cell surface protein [Clostridium diffic...
631
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05635
(
show subtarget assignments
)
1
cloned
No
CD2193
126699809
cell surface protein [Clostridium diffic...
480
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05306
(
show subtarget assignments
)
1
cloned
No
CD2786
126700402
cell surface protein [Clostridium diffic...
525
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05310
(
show subtarget assignments
)
1
soluble
No
CD0844
126698424
cell surface protein [Clostridium diffic...
313
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05640
(
show subtarget assignments
)
1
cloned
No
CD2767
126700383
cell surface protein [Clostridium diffic...
703
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05214
(
show subtarget assignments
)
1
cloned
No
CD2796
126700412
cell surface protein [Clostridium diffic...
626
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05629
(
show subtarget assignments
)
1
soluble
No
CD1803
126699412
cell surface protein [Clostridium diffic...
581
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05617
(
show subtarget assignments
)
1
cloned
No
CD0440
126698013
cell surface protein [Clostridium diffic...
386
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05068
(
show subtarget assignments
)
1
soluble
No
CD2735
126700350
cell surface protein [Clostridium diffic...
475
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2KQ8
5.5%
Clostridium difficile
Cell envelope: Other
IDP05092
(
show subtarget assignments
)
1
cloned
No
CD1047
126698631
cell surface protein [Clostridium diffic...
350
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05350
(
show subtarget assignments
)
1
cloned
No
CD3192
126700811
cell surface protein [Clostridium diffic...
550
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05639
(
show subtarget assignments
)
1
soluble
No
CD2713
126700327
cell surface protein [Clostridium diffic...
653
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2V04
14.4%
Clostridium difficile
Cell envelope: Other
IDP05259
(
show subtarget assignments
)
1
cloned
No
CD2782
126700398
cell surface protein [Clostridium diffic...
351
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05104
(
show subtarget assignments
)
1
cloned
No
CD1233
126698829
cell surface protein [Clostridium diffic...
475
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05532
(
show subtarget assignments
)
1
soluble
No
CD2784
126700400
cell surface protein [Clostridium diffic...
675
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3NE8
9.6%
Clostridium difficile
Cell envelope: Other
IDP05109
(
show subtarget assignments
)
1
cloned
No
CD1987
126699595
cell surface protein [Clostridium diffic...
478
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05069
(
show subtarget assignments
)
1
cloned
No
CD2789
126700405
cwp66
cell surface protein [Clostridium diffic...
610
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05637
(
show subtarget assignments
)
1
cloned
No
CD2518
126700135
cell surface protein [Clostridium diffic...
456
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05745
(
show subtarget assignments
)
1
expressed
No
CD2787
126700403
cwp84
cell surface protein (putative cell surf...
803
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1FH0
8.2%
Clostridium difficile
Cell envelope: Other
IDP05107
(
show subtarget assignments
)
1
soluble
No
CD1751
126699358
cell surface protein (putative cell surf...
795
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1VSN
8.4%
Clostridium difficile
Cell envelope: Other
IDP05618
(
show subtarget assignments
)
1
cloned
No
CD0514
126698095
cell surface protein (putative hemagglut...
1630
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05346
(
show subtarget assignments
)
1
soluble
No
CD1036
126698620
cell surface protein (putative N-acetylm...
677
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3NE8
8.4%
Clostridium difficile
Cell envelope: Other
IDP05106
(
show subtarget assignments
)
1
cloned
No
CD1469
126699073
cell surface protein (putative penicilli...
990
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2QMI
10%
Clostridium difficile
Cell envelope: Other
IDP05260
(
show subtarget assignments
)
1
cloned
No
CD2791
126700407
cell surface protein (putative S-layer p...
623
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05263
(
show subtarget assignments
)
1
cloned
No
CD2793
126700409
slpA
cell surface protein (S-layer precursor ...
719
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3CVZ
36.4%
Clostridium difficile
Cell envelope: Other
IDP05315
(
show subtarget assignments
)
1
cloned
No
BAS0383
49183411
-
cell wall anchor domain-containing prote...
267
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3HQV
23.6%
Bacillus anthracis
Cell envelope: Other
IDP05012
(
show subtarget assignments
)
1
cloned
No
BA_5070
30259559
cell wall surface anchor family protein ...
148
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP01796
(
show subtarget assignments
)
1
cloned
No
GBAA5258
47778380
cell wall surface anchor family protein ...
627
Drug target homolog; Drug target functions
Phase 3: June 2008
Bacillus anthracis
Cell envelope
Other
IDP91909
(
show subtarget assignments
)
8
selected
No
SpneCM_010100002785
298254524
cell wall surface anchor family protein,...
246
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91997
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004547
298254868
cell wall surface anchor family protein,...
415
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91913
(
show subtarget assignments
)
8
selected
No
SpneCM_010100006539
298255249
cell wall surface anchor family protein ...
334
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP92091
(
show subtarget assignments
)
8
selected
No
TGME49_014210
237842913
centromere/microtubule binding protein, ...
505
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3U28
49.9%
Toxoplasma gondii
IDP91785
(
show subtarget assignments
)
8
purified
No
ABQ00063
145974708
cfr
Cfr [Staphylococcus aureus]
349
drug resistance /
Chloramphenicol-florfenicol resistance protein
Community Requests
3RF9
33.5%
Staphylococcus aureus
IDP92564
(
show subtarget assignments
)
8
selected
No
3L6P_A
290560467
Chain A, Crystal Structure Of Dengue Vir...
236
potential drug target /
Dengue plasmid entered for cocrystal studies with a small molecule West Nile pro...
Community Requests
3L6P
100%
Dengue virus
IDP92561
(
show subtarget assignments
)
8
selected
No
3EQV_A
209870568
Chain A, Crystal Structure Of Penicillin...
542
potential drug target /
Pptase, FactorXa, HCV NS3/NS4A, Trypsin and Elastase/Subtilisin (see below)] and...
Community Requests
3EQV
99.8%
Neisseria gonorrhoeae
IDP92560
(
show subtarget assignments
)
8
selected
No
1PYY_A
37927671
Chain A, Double Mutant Pbp2x T338aM339F ...
702
potential drug target /
Pptase, FactorXa, HCV NS3/NS4A, Trypsin and Elastase/Subtilisin (see below)] and...
Community Requests
1PYY
100%
Streptococcus pneumoniae
IDP92559
(
show subtarget assignments
)
8
selected
No
1MWR_A
24987837
Chain A, Structure Of Semet Penicillin B...
646
potential drug target /
Pptase, FactorXa, HCV NS3/NS4A, Trypsin and Elastase/Subtilisin (see below)] and...
Community Requests
1MWR
97.4%
Staphylococcus aureus
IDP92563
(
show subtarget assignments
)
8
selected
No
3E90_B
221046696
Chain B, West Nile Vi Rus Ns2b-Ns3protea...
198
potential drug target /
We have identified a number of small molecule inhibitor to West Nile and/or deng...
Community Requests
3E90
100%
West Nile
IDP01112
(
show subtarget assignments
)
1
in_pdb
3G48
No
BA_2064
30256713
csaA
chaperone CsaA
109
Conserved Gene / Pathway
Phase 2: March 2008
3G48
99.1%
Bacillus anthracis
Protein fate
Protein and peptide secretion and trafficking
IDP91617
(
show subtarget assignments
)
8
purified
No
BAB36908
13362956
ECs3485
chaperone-like protein [Escherichia coli...
196
virulence/pathogenesis /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3LW8
41.3%
Escherichia coli
IDP00478
(
show subtarget assignments
)
1
purified
No
YPO0469
16120798
dnaJ
chaperone protein DnaJ
379
Conserved Gene / Pathway
Phase 2: March 2008
3LZ8
32.7%
Yersinia pestis
Protein fate
Protein folding and stabilization
IDP01653
(
show subtarget assignments
)
1
cloned
No
GBAA4538
47529835
dnaJ
chaperone protein dnaJ [Bacillus anthrac...
371
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
3LZ8
34%
Bacillus anthracis
Protein fate
Protein folding and stabilization
IDP02168
(
show subtarget assignments
)
1
expressed
No
CBU_1289
29541857
dnaJ
chaperone protein dnaJ [Coxiella burneti...
374
Conserved; Drug target functions
Phase 3: June 2008
3LZ8
32.1%
Coxiella burnetii
Protein fate
Protein folding and stabilization
IDP02646
(
show subtarget assignments
)
1
expressed
No
CBU_1290
29541858
dnaK
chaperone protein dnak [Coxiella burneti...
656
Conserved; Drug target functions
Phase 3: June 2008
2KHO
68.9%
Coxiella burnetii
Protein fate
Protein folding and stabilization
IDP00774
(
show subtarget assignments
)
1
cloned
No
SACOL0597
57285613
chaperone protein HchA
292
Drug Target Function
Phase 2: March 2008
1IZY
54.1%
Staphylococcus aureus
Hypothetical proteins
Conserved
IDP01010
(
show subtarget assignments
)
1
purified
No
STM2539
16765859
hscA
chaperone protein HscA
616
Conserved Gene / Pathway
Phase 2: March 2008
2KHO
40.9%
Salmonella enterica
Protein fate
Protein folding and stabilization
IDP01396
(
show subtarget assignments
)
1
purified
No
VC0752
15640771
hscA
chaperone protein HscA
616
Conserved Gene / Pathway
Phase 2: March 2008
2KHO
40.9%
Vibrio cholerae
Protein fate
Protein folding and stabilization
IDP01643
(
show subtarget assignments
)
1
crystallized
No
YPO2892
16123083
hscA
chaperone protein HscA [Yersinia pestis ...
650
CD; Drug target functions
Phase 3: June 2008
2KHO
37.8%
Yersinia pestis
Protein fate
Protein folding and stabilization
IDP02384
(
show subtarget assignments
)
1
expressed
No
GBAA3202
47528494
hscC
chaperone protein hscC [Bacillus anthrac...
566
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
2V7Y
38%
Bacillus anthracis
Protein fate
Protein folding and stabilization
IDP01690
(
show subtarget assignments
)
1
soluble
No
CBU_1719
29542277
groES
chaperonin, 10 kDa [Coxiella burnetii RS...
96
Conserved; Drug target functions
Phase 3: June 2008
3NX6
58.3%
Coxiella burnetii
Protein fate
Protein folding and stabilization
IDP02390
(
show subtarget assignments
)
1
cloned
No
CBU_1718
29542276
groEL
chaperonin, 60 kDa [Coxiella burnetii RS...
552
Conserved; Drug target functions
Phase 3: June 2008
2EU1
75.5%
Coxiella burnetii
Protein fate
Protein folding and stabilization
IDP01497
(
show subtarget assignments
)
1
in_crystallization_trials
No
VCA0820
15601575
groEL
chaperonin GroEL
530
Conserved Gene / Pathway
Phase 2: March 2008
1AON
74.2%
Vibrio cholerae
Protein fate
Protein folding and stabilization
IDP00685
(
show subtarget assignments
)
1
purified
No
SACOL2016
57284887
groEL
chaperonin GroEL
538
Drug Target Function
Phase 2: March 2008
3RTK
59.3%
Staphylococcus aureus
Protein fate
Protein folding and stabilization
IDP02516
(
show subtarget assignments
)
1
purified
No
FTT1696
56708705
groEL
chaperonin GroEL [Francisella tularensis...
544
Conserved; Drug target functions
Phase 3: June 2008
1AON
73.3%
Francisella tularensis
Protein fate
Protein folding and stabilization
previous
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
20
|
next
Filter Columns
Filter Columns:
Target Id
Locus Tag
Priority
Stage
Has Screening
Ncbi Gi
Gene Name
Common Name
Length
Justification
Project
Homolog Pdb Id
Homolog Sequence Identity
Organism
Tigr Main Role
Tigr Sub Role
