|
|---|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Selection
Phase |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP01855
(show subtarget assignments)
|
1 |
soluble |
No |
STM1162 |
16764518 |
dinI |
DNA damage-inducible protein I [Salmonel... |
81 |
Phase 3: June 2008 |
1GHH
|
85.2% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02693
(show subtarget assignments)
|
1 |
crystallized |
No |
FTT0185 |
56707350 |
ddlB |
D-alanine--D-alanine ligase B [Francisel... |
296 |
Phase 3: June 2008 |
3V4Z
|
43.9% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP01849
(show subtarget assignments)
|
1 |
in_pdb
3L07 |
No |
FTT0892 |
56707993 |
folD |
methylenetetrahydrofolate dehydrogenase/... |
282 |
Phase 3: June 2008 |
3L07
|
100% |
Francisella tularensis |
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers |
Aspartate familyFolic acid |
|
|
|
IDP02682
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_1502 |
29542061 |
era |
GTP-binding protein Era [Coxiella burnet... |
295 |
Phase 3: June 2008 |
1EGA
|
51.2% |
Coxiella burnetii |
Regulatory functions |
RNA interactions |
|
|
|
IDP02684
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0405 |
56707554 |
lolD |
lipoprotein releasing system, subunit D,... |
231 |
Phase 3: June 2008 |
1F3O
|
44.6% |
Francisella tularensis |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP01847
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA5416 |
47530729 |
ftsE |
cell division ABC transporter, ATP-bindi... |
214 |
Phase 3: June 2008 |
3DHW
|
41.1% |
Bacillus anthracis |
Cellular processes |
Cell division |
|
|
|
IDP01845
(show subtarget assignments)
|
1 |
cloned |
No |
STM0017 |
16763407 |
|
hypothetical protein STM0017 [Salmonella... |
147 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02673
(show subtarget assignments)
|
1 |
expressed |
No |
STM4466 |
16767711 |
|
carbamate kinase [Salmonella typhimurium... |
310 |
Phase 3: June 2008 |
1E19
|
45.5% |
Salmonella enterica |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP02455
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA3813 |
47529098 |
|
prophage LambdaBa01, thymidylate synthas... |
252 |
Phase 3: June 2008 |
3AH5
|
24.6% |
Bacillus anthracis |
Purines, pyrimidines, nucleosides, and nucleotides |
2'-Deoxyribonucleotide metabolism |
|
|
|
IDP01701
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1970 |
29542525 |
dapF |
diaminopimelate epimerase [Coxiella burn... |
276 |
Phase 3: June 2008 |
1GQZ
|
48.9% |
Coxiella burnetii |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP02675
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1842 |
29542398 |
|
GTP-binding protein YchF [Coxiella burne... |
363 |
Phase 3: June 2008 |
1JAL
|
65.3% |
Coxiella burnetii |
Unknown function |
General |
|
|
|
IDP01846
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1419 |
29541979 |
|
serine hydroxymethyltransferase [Coxiell... |
419 |
Phase 3: June 2008 |
1DFO
|
68.5% |
Coxiella burnetii |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP01853
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1669 |
29542228 |
rpoS |
RNA polymerase sigma factor RpoS [Coxiel... |
352 |
Phase 3: June 2008 |
3IYD
|
31.5% |
Coxiella burnetii |
Transcription |
Transcription factors |
|
|
|
IDP02681
(show subtarget assignments)
|
1 |
soluble |
No |
STM3682 |
16766967 |
selB |
selenocysteinyl-tRNA-specific translatio... |
616 |
Phase 3: June 2008 |
1D8T
|
19% |
Salmonella enterica |
Protein synthesis |
Translation factors |
|
|
|
IDP01840
(show subtarget assignments)
|
1 |
soluble |
No |
STM2861 |
16766167 |
sitA |
putative periplasmic binding protein [Sa... |
305 |
Phase 3: June 2008 |
1XVL
|
53.4% |
Salmonella enterica |
Cell envelope |
Other |
|
|
|
IDP01842
(show subtarget assignments)
|
1 |
in_pdb
3SLH
4EGR
3ROI |
Yes |
CBU_0526 |
29541129 |
aroA |
3-phosphoshikimate 1-carboxyvinyltransfe... |
438 |
Phase 3: June 2008 |
3ROI
|
100% |
Coxiella burnetii |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP02665
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0469 |
56707611 |
ksgA |
dimethyladenosine transferase [Francisel... |
262 |
Phase 3: June 2008 |
3TQS
|
40.8% |
Francisella tularensis |
Cellular processesProtein synthesis |
Toxin production and resistancetRNA and rRNA base modification |
|
|
|
IDP01838
(show subtarget assignments)
|
1 |
cloned |
No |
STM0941 |
16764303 |
ybjY |
macrolide transporter subunit MacA [Salm... |
372 |
Phase 3: June 2008 |
3FPP
|
79% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01841
(show subtarget assignments)
|
1 |
purified |
No |
STM2549 |
16765869 |
asrB |
anaerobic sulfite reductase subunit B [S... |
272 |
Phase 3: June 2008 |
1KRH
|
18.8% |
Salmonella enterica |
Energy metabolism |
Anaerobic |
|
|
|
IDP02670
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4353 |
47529649 |
argB |
acetylglutamate kinase [Bacillus anthrac... |
255 |
Phase 3: June 2008 |
2BTY
|
43.1% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP01833
(show subtarget assignments)
|
1 |
cloned |
No |
STM2476 |
16765796 |
ypfG |
putative periplasmic protein [Salmonella... |
347 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01834
(show subtarget assignments)
|
1 |
soluble |
No |
STM2345 |
16765672 |
|
putative transcriptional regulator [Salm... |
339 |
Phase 3: June 2008 |
3H5O
|
33.9% |
Salmonella enterica |
Energy metabolism |
Entner-Doudoroff |
|
|
|
IDP02653
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2840 |
16766146 |
|
anaerobic nitric oxide reductase flavoru... |
479 |
Phase 3: June 2008 |
1YCF
|
33.8% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP01604
(show subtarget assignments)
|
1 |
crystallized |
No |
CBU_0704 |
29541308 |
rfbI |
lipopolysaccharide/O-antigen ABC transpo... |
258 |
Phase 3: June 2008 |
3QF4
|
25.6% |
Coxiella burnetii |
Transport and binding proteins |
Other |
|
|
|
IDP01835
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0152 |
29540772 |
coaE |
dephospho-CoA kinase [Coxiella burnetii ... |
199 |
Phase 3: June 2008 |
1JJV
|
45.7% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP01691
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1575 |
29542135 |
tolR |
tolR protein [Coxiella burnetii RSA 493]... |
147 |
Phase 3: June 2008 |
|
|
Coxiella burnetii |
Transport and binding proteins |
Other |
|
|
|
IDP02368
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT0422 |
56707569 |
murF |
UDP-N--acetylmuramoylalanyl-D-glutamyl-2... |
452 |
Phase 3: June 2008 |
1GG4
|
33.6% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP01692
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1671 |
56708681 |
ribD |
riboflavin biosynthesis protein ribD [Fr... |
355 |
Phase 3: June 2008 |
2B3Z
|
37.7% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP02438
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0029 |
29540654 |
|
acyltransferase family protein [Coxiella... |
242 |
Phase 3: June 2008 |
|
|
Coxiella burnetii |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02652
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA1422 |
47526694 |
leuC |
isopropylmalate isomerase large subunit ... |
464 |
Phase 3: June 2008 |
2B3X
|
22% |
Bacillus anthracis |
Amino acid biosynthesis |
Pyruvate family |
|
|
|
IDP02648
(show subtarget assignments)
|
1 |
soluble |
No |
FTT0064 |
56707243 |
atpD |
F0F1 ATP synthase subunit beta [Francise... |
458 |
Phase 3: June 2008 |
3OAA
|
81.3% |
Francisella tularensis |
Energy metabolism |
ATP-proton motive force interconversion |
|
|
|
IDP01695
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA0228 |
47525485 |
|
ABC transporter ATP-binding protein [Bac... |
626 |
Phase 3: June 2008 |
1YQT
|
20.9% |
Bacillus anthracis |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02431
(show subtarget assignments)
|
1 |
crystallized |
No |
CBU_1770 |
29542327 |
|
ABC transporter, ATP-binding protein [Co... |
432 |
Phase 3: June 2008 |
2YYZ
|
23.1% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP01826
(show subtarget assignments)
|
1 |
in_pdb
3LAY |
No |
STM4172 |
16767426 |
zraP |
zinc resistance protein [Salmonella typh... |
151 |
Phase 3: June 2008 |
3LAY
|
100% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02444
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2224 |
16122453 |
|
hypothetical protein YPO2224 [Yersinia p... |
103 |
Phase 3: June 2008 |
|
|
Yersinia pestis |
Cell envelope |
Other |
|
|
|
IDP01613
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM1927 |
16765269 |
yecG |
universal stress protein UspC [Salmonell... |
142 |
Phase 3: June 2008 |
1JMV
|
35.2% |
Salmonella enterica |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP01609
(show subtarget assignments)
|
1 |
crystallized |
No |
FTT1512c |
56708550 |
dnaJ1 |
heat shock protein, hsp40 [Francisella t... |
308 |
Phase 3: June 2008 |
3LZ8
|
34.2% |
Francisella tularensis |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP01649
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0796 |
29541390 |
|
HIT family protein [Coxiella burnetii RS... |
113 |
Phase 3: June 2008 |
1AV5
|
49.6% |
Coxiella burnetii |
Unknown function |
General |
|
|
|
IDP01819
(show subtarget assignments)
|
1 |
cloned |
No |
STM1145 |
16764501 |
csgC |
putative autoagglutination protein [Salm... |
108 |
Phase 3: June 2008 |
2Y2T
|
64.8% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP01817
(show subtarget assignments)
|
1 |
cloned |
No |
STM1143 |
16764499 |
csgB |
curlin minor subunit [Salmonella typhimu... |
151 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Cellular processes |
Pathogenesis |
|
|
|
IDP01815
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1382 |
29541947 |
uppS |
undecaprenyl diphosphate synthase [Coxie... |
237 |
Phase 3: June 2008 |
1JP3
|
49.4% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP01816
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM3193 |
16766493 |
|
putative disulfide bond formation protei... |
223 |
Phase 3: June 2008 |
3L9U
|
89.2% |
Salmonella enterica |
Protein synthesis |
Translation factors |
|
|
|
IDP02630
(show subtarget assignments)
|
1 |
expressed |
No |
STM2899 |
16766205 |
invF |
invasion regulatory protein [Salmonella ... |
216 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02644
(show subtarget assignments)
|
1 |
purified |
No |
FTT0074 |
56707253 |
sdhA |
succinate dehydrogenase, catalytic and N... |
597 |
Phase 3: June 2008 |
1NEK
|
61.4% |
Francisella tularensis |
Energy metabolism |
TCA cycle |
|
|
|
IDP02625
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4457 |
47529752 |
aroK |
shikimate kinase [Bacillus anthracis str... |
165 |
Phase 3: June 2008 |
1ZUH
|
35.2% |
Bacillus anthracis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP02624
(show subtarget assignments)
|
1 |
soluble |
No |
FTT1562 |
56708589 |
ispA |
geranyltranstransferase [Francisella tul... |
293 |
Phase 3: June 2008 |
2FOR
|
40.3% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP02628
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2923 |
16766229 |
|
putative cytoplasmic protein [Salmonella... |
78 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02618
(show subtarget assignments)
|
1 |
cloned |
No |
STM2205 |
16765535 |
fruK |
1-phosphofructokinase [Salmonella typhim... |
312 |
Phase 3: June 2008 |
3CQD
|
31.1% |
Salmonella enterica |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP02259
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2164 |
47527458 |
|
ABC transporter ATP-binding protein [Bac... |
631 |
Phase 3: June 2008 |
1YQT
|
21.4% |
Bacillus anthracis |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP01812
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1764c |
56708759 |
|
ferredoxin [Francisella tularensis subsp... |
107 |
Phase 3: June 2008 |
1A6L
|
64.5% |
Francisella tularensis |
Energy metabolism |
Electron transport |
|
|
|
IDP02426
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1952 |
29542507 |
|
ABC transporter, ATP-binding protein [Co... |
532 |
Phase 3: June 2008 |
2IW3
|
26.4% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02629
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_1006 |
29541588 |
bioF |
8-amino-7-oxononanoate synthase [Coxiell... |
384 |
Phase 3: June 2008 |
1BS0
|
37.8% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP02615
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA4677 |
47529976 |
|
ribonuclease [Bacillus anthracis str. 'A... |
458 |
Phase 3: June 2008 |
2BX2
|
27.7% |
Bacillus anthracis |
Cellular processes |
Cell division |
|
|
|
IDP01793
(show subtarget assignments)
|
1 |
in_pdb
3QDN |
No |
STM0504 |
16763884 |
ybbN |
putative thioredoxin protein [Salmonella... |
284 |
Phase 3: June 2008 |
3QDN
|
100% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP02608
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0178 |
29540794 |
|
ABC transporter, ATP-binding protein [Co... |
252 |
Phase 3: June 2008 |
1V43
|
43.3% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP01802
(show subtarget assignments)
|
1 |
crystallized |
No |
FTT0062 |
56707241 |
atpA |
F0F1 ATP synthase subunit alpha [Francis... |
513 |
Phase 3: June 2008 |
3OAA
|
71% |
Francisella tularensis |
Energy metabolism |
ATP-proton motive force interconversion |
|
|
|
IDP01784
(show subtarget assignments)
|
1 |
expressed |
No |
STM1383 |
16764733 |
ttrA |
tetrathionate reductase complex subunit ... |
1020 |
Phase 3: June 2008 |
2IVF
|
18.1% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP01785
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0667 |
29541271 |
dapD |
2,3,4,5-tetrahydropyridine-2,6-dicarboxy... |
271 |
Phase 3: June 2008 |
1KGQ
|
62.7% |
Coxiella burnetii |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP01822
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0317 |
56707470 |
uppS |
undecaprenyl pyrophosphate synthetase [F... |
257 |
Phase 3: June 2008 |
1JP3
|
43.6% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP01985
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1882 |
29542439 |
hemL |
glutamate-1-semialdehyde-2,1-aminomutase... |
435 |
Phase 3: June 2008 |
4E77
|
60.7% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP01779
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_0366 |
29540977 |
phoR |
sensor histidine kinase PhoR protein, pu... |
252 |
Phase 3: June 2008 |
2C2A
|
31.3% |
Coxiella burnetii |
Signal transduction |
Two-component systems |
|
|
|
IDP02600
(show subtarget assignments)
|
1 |
expressed |
No |
STM2279 |
16765606 |
yfaE |
2Fe-2S ferredoxin YfaE [Salmonella typhi... |
84 |
Phase 3: June 2008 |
1IUE
|
37.2% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02129
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0450 |
29541057 |
ffh |
signal recognition particle protein [Cox... |
461 |
Phase 3: June 2008 |
2XXA
|
57.3% |
Coxiella burnetii |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP01780
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM0784 |
16764148 |
ybhA |
phosphotransferase [Salmonella typhimuri... |
272 |
Phase 3: June 2008 |
2PQ0
|
30.5% |
Salmonella enterica |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP01786
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0502 |
29541107 |
|
hydrolase, putative [Coxiella burnetii R... |
225 |
Phase 3: June 2008 |
2GZX
|
44.9% |
Coxiella burnetii |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02594
(show subtarget assignments)
|
1 |
soluble |
No |
STM1539 |
16764884 |
|
putative hydrogenase-1 small subunit [Sa... |
367 |
Phase 3: June 2008 |
3RGW
|
66.8% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP02604
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1893 |
29542450 |
aroB |
3-dehydroquinate synthase [Coxiella burn... |
360 |
Phase 3: June 2008 |
3OKF
|
48.6% |
Coxiella burnetii |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01797
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1008 |
29541590 |
bioA |
adenosylmethionine-8-amino-7-oxononanoat... |
442 |
Phase 3: June 2008 |
3DOD
|
35.4% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP02607
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0101 |
29540723 |
nadB |
L-aspartate oxidase [Coxiella burnetii R... |
536 |
Phase 3: June 2008 |
1CHU
|
52.4% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridine nucleotides |
|
|
|
IDP02587
(show subtarget assignments)
|
1 |
cloned |
No |
STM2571 |
16765891 |
murQ |
N-acetylmuramic acid-6-phosphate etheras... |
297 |
Phase 3: June 2008 |
1NRI
|
51.9% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02584
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM1301 |
16764652 |
|
pyrimidine (deoxy)nucleoside triphosphat... |
138 |
Phase 3: June 2008 |
2RRK
|
75.4% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02592
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA1308 |
47526573 |
|
glycolate oxidase, iron-sulfur subunit, ... |
442 |
Phase 3: June 2008 |
|
|
Bacillus anthracis |
Energy metabolism |
Other |
|
|
|
IDP01803
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_0646 |
29541247 |
ribE |
riboflavin synthase, alpha subunit [Coxi... |
202 |
Phase 3: June 2008 |
1I8D
|
37.7% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP01805
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1084 |
29541658 |
|
sensory box sensor histidine kinase/resp... |
683 |
Phase 3: June 2008 |
2C2A
|
12.4% |
Coxiella burnetii |
Signal transduction |
Two-component systems |
|
|
|
IDP02257
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_2074 |
29542624 |
hemC |
porphobilinogen deaminase [Coxiella burn... |
307 |
Phase 3: June 2008 |
1AH5
|
46.3% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP02622
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_0109 |
29540729 |
|
ABC transporter, periplasmic substrate-b... |
267 |
Phase 3: June 2008 |
3TQW
|
88.4% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP01810
(show subtarget assignments)
|
1 |
cloned |
No |
STM3187 |
16766487 |
ygiB |
hypothetical protein STM3187 [Salmonella... |
223 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP01811
(show subtarget assignments)
|
1 |
expressed |
No |
FTT0908 |
56708009 |
parB |
chromosome partition protein B [Francise... |
304 |
Phase 3: June 2008 |
1VZ0
|
23.7% |
Francisella tularensis |
Cellular processes |
Cell division |
|
|
|
IDP02424
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1147c |
56708218 |
dfp |
4'-phosphopantothenoylcysteine decarboxy... |
391 |
Phase 3: June 2008 |
1U7U
|
19.4% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP01820
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5463 |
47530777 |
thiC |
thiamine biosynthesis protein ThiC [Baci... |
586 |
Phase 3: June 2008 |
3EPM
|
66.9% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Thiamine |
|
|
|
IDP01813
(show subtarget assignments)
|
1 |
purified |
No |
GBAA1253 |
47526519 |
trpB |
tryptophan synthase subunit beta [Bacill... |
397 |
Phase 3: June 2008 |
1X1Q
|
63% |
Bacillus anthracis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01814
(show subtarget assignments)
|
1 |
expressed |
No |
STM1753 |
16765097 |
hnr |
response regulator of RpoS [Salmonella t... |
337 |
Phase 3: June 2008 |
3EOD
|
35.3% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02363
(show subtarget assignments)
|
1 |
purified |
No |
FTT1366c |
56708419 |
pyk |
pyruvate kinase [Francisella tularensis ... |
478 |
Phase 3: June 2008 |
1E0U
|
39.5% |
Francisella tularensis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP02429
(show subtarget assignments)
|
1 |
expressed |
No |
FTT0723c |
56707841 |
|
Short-chain dehydrogenase/reductase fami... |
262 |
Phase 3: June 2008 |
4E3Z
|
35.9% |
Francisella tularensis |
Energy metabolism |
Other |
|
|
|
IDP02616
(show subtarget assignments)
|
1 |
in_pdb
3LHQ |
Yes |
STM0477 |
16763857 |
acrR |
DNA-binding transcriptional repressor Ac... |
217 |
Phase 3: June 2008 |
3LHQ
|
100% |
Salmonella enterica |
Transport and binding proteins |
Other |
|
|
|
IDP02564
(show subtarget assignments)
|
1 |
purified |
No |
GBAA0084 |
47525340 |
ispD |
2-C-methyl-D-erythritol 4-phosphate cyti... |
226 |
Phase 3: June 2008 |
1W77
|
36.7% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP01769
(show subtarget assignments)
|
1 |
soluble |
No |
STM2532 |
16765852 |
|
putative inner membrane lipoprotein [Sal... |
1644 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02565
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_0648 |
29541249 |
ribH |
6,7-dimethyl-8-ribityllumazine synthase ... |
151 |
Phase 3: June 2008 |
1VSW
|
47.7% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP02578
(show subtarget assignments)
|
1 |
expressed |
No |
STM0262 |
16763645 |
yafS |
putative SAM-dependent methyltransferase... |
240 |
Phase 3: June 2008 |
1VLM
|
11.7% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP02562
(show subtarget assignments)
|
1 |
purified |
No |
STM0924 |
16764286 |
|
putative CuZn superoxide dismutase [Salm... |
174 |
Phase 3: June 2008 |
2WN0
|
60.3% |
Salmonella enterica |
Cellular processes |
Detoxification |
|
|
|
IDP02555
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0391 |
29541001 |
ribF |
riboflavin biosynthesis protein RibF [Co... |
320 |
Phase 3: June 2008 |
1MRZ
|
33.1% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP02271
(show subtarget assignments)
|
1 |
crystallized |
No |
FTT1155c |
56708226 |
aroK |
shikimate kinase I [Francisella tularens... |
176 |
Phase 3: June 2008 |
1KAG
|
58% |
Francisella tularensis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01825
(show subtarget assignments)
|
1 |
cloned |
No |
STM2265 |
16765593 |
ada |
O6-methylguanine-DNA methyltransferase/t... |
353 |
Phase 3: June 2008 |
1SFE
|
37.7% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP01824
(show subtarget assignments)
|
1 |
cloned |
No |
STM3197 |
16766497 |
glgS |
glycogen synthesis protein GlgS [Salmone... |
69 |
Phase 3: June 2008 |
1RRZ
|
73.9% |
Salmonella enterica |
Energy metabolism |
Biosynthesis and degradation of polysaccharides |
|
|
|
IDP02561
(show subtarget assignments)
|
1 |
purified |
No |
FTT0714c |
56707833 |
kbl |
2-amino-3-ketobutyrate coenzyme A ligase... |
398 |
Phase 3: June 2008 |
1FC4
|
62.1% |
Francisella tularensis |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP01608
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1504 |
29542063 |
lepB-2 |
signal peptidase I [Coxiella burnetii RS... |
256 |
Phase 3: June 2008 |
1B12
|
36.3% |
Coxiella burnetii |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP01685
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT0757 |
56707872 |
galU |
UTP--glucose-1-phosphate uridylyltransfe... |
287 |
Phase 3: June 2008 |
2E3D
|
47.8% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP02270
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_1424 |
29541984 |
hemB |
porphobilinogen synthase [Coxiella burne... |
334 |
Phase 3: June 2008 |
1W1Z
|
48.8% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP02360
(show subtarget assignments)
|
1 |
soluble |
No |
FTT1270c |
56708330 |
grpE |
heat shock protein GrpE [Francisella tul... |
195 |
Phase 3: June 2008 |
1DKG
|
36.9% |
Francisella tularensis |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP02316
(show subtarget assignments)
|
1 |
soluble |
No |
FTT0037 |
56707217 |
nuoG |
NADH dehydrogenase subunit G [Francisell... |
788 |
Phase 3: June 2008 |
2FUG
|
24.2% |
Francisella tularensis |
Energy metabolism |
Electron transport |
|
|
|
