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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 11 of 60, showing 100 records out of 5973 total, starting on record 1001
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90958
(
show subtarget assignments
)
8
cloned
No
UTI89_C1702
122423767
Hypothetical protein
807
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
1V9Y
18%
Escherichia coli
IDP90959
(
show subtarget assignments
)
8
cloned
No
PP2258
81441302
Sensory box protein
562
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
2R6O
20.6%
Pseudomonas putida
IDP90963
(
show subtarget assignments
)
8
cloned
No
VP2446
81727013
C-di-GMP phosphodiesterase A-related pro...
679
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
15.5%
Vibrio parahaemolyticus
IDP90962
(
show subtarget assignments
)
8
purified
No
VC2750
81544306
GGDEF family protein
849
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
2R6O
13%
Vibrio cholerae
IDP90964
(
show subtarget assignments
)
8
purified
No
VC0072
81545617
Sensory box/GGDEF family protein
768
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
15.4%
Vibrio cholerae
IDP90965
(
show subtarget assignments
)
8
purified
No
VF0094
75354809
Sensory box/GGDEF family protein
852
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
11.2%
Vibrio fischeri
IDP90975
(
show subtarget assignments
)
8
cloned
No
y0011
22123933
hypothetical protein y0011 [Yersinia pes...
229
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
2DI3
21.4%
Yersinia pestis
IDP90973
(
show subtarget assignments
)
8
selected
No
AND4_00045
163803697
RTX toxin RtxA [Vibrio sp. AND4]
525
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Vibrio sp.
IDP90976
(
show subtarget assignments
)
8
cloned
No
y0137
22124057
degQ
protease [Yersinia pestis KIM 10]
463
other biological interest /
bifunctional chaperone / protease
Community Requests
4A8A
67.6%
Yersinia pestis
IDP90977
(
show subtarget assignments
)
8
soluble
No
y0320
22124237
oxyR
DNA-binding transcriptional regulator Ox...
305
other biological interest /
important global regulator
Community Requests
1I6A
59.7%
Yersinia pestis
IDP90981
(
show subtarget assignments
)
8
selected
No
y0850
22124761
outer membrane receptor [Yersinia pestis...
731
other biological interest /
putative iron-binding TonB-dependent outer membrane receptor
Community Requests
2HDF
31.1%
Yersinia pestis
IDP90980
(
show subtarget assignments
)
8
cloned
No
y0801
22124714
iron-sulfur cluster insertion protein Er...
119
other biological interest /
protein possibly involved in iron-sulfur cluster synthesis
Community Requests
2APN
75.6%
Yersinia pestis
IDP90982
(
show subtarget assignments
)
8
soluble
No
y0869
22124780
cybC
cytochrome b(562) [Yersinia pestis KIM 1...
100
other biological interest /
uncharacterized periplasmic cytochrome
Community Requests
4ER9
53%
Yersinia pestis
IDP90983
(
show subtarget assignments
)
8
selected
No
y0870
22124781
katG
catalase-peroxidase [Yersinia pestis KIM...
751
virulence/pathogenesis /
stress response protein and antigen in Y pestis
Community Requests
2FXG
59.4%
Yersinia pestis
IDP90988
(
show subtarget assignments
)
8
expressed
No
y1189
22125092
gltI
glutamate and aspartate transporter subu...
305
other biological interest /
-
Community Requests
2IA4
75.7%
Yersinia pestis
IDP90987
(
show subtarget assignments
)
8
crystallized
No
y1125
22125029
hypothetical protein y1125 [Yersinia pes...
297
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
1VP5
57.2%
Yersinia pestis
IDP90989
(
show subtarget assignments
)
8
soluble
No
y1222
22125124
nrdF
ribonucleotide-diphosphate reductase sub...
323
other biological interest /
iron-regulated reductase
Community Requests
3N37
78.3%
Yersinia pestis
IDP90990
(
show subtarget assignments
)
8
selected
No
y1223
22125125
nrdE
ribonucleotide-diphosphate reductase sub...
716
iron-regulated reductase
Community Requests
1PEM
72.6%
Yersinia pestis
IDP90993
(
show subtarget assignments
)
8
selected
No
y1334
22125233
cysteine desulfurase [Yersinia pestis KI...
409
other biological interest /
enzyme involved in iron-sulfur cluster synthesis
Community Requests
1P3W
87.8%
Yersinia pestis
IDP90994
(
show subtarget assignments
)
8
purified
No
y1355
22125254
hypothetical protein y1355 [Yersinia pes...
211
other biological interest /
-
Community Requests
Yersinia pestis
IDP90996
(
show subtarget assignments
)
8
in_pdb
4DYU
No
y1677
22125572
dps
DNA starvation/stationary phase protecti...
167
other biological interest /
global stress response protein
Community Requests
4DYU
100%
Yersinia pestis
IDP90997
(
show subtarget assignments
)
8
soluble
No
y1682
22125577
ompX
outer membrane protein X [Yersinia pesti...
176
virulence/pathogenesis /
putative cell surface adhesin in various Gram-negative pathogens
Community Requests
1ORM
59.1%
Yersinia pestis
IDP91008
(
show subtarget assignments
)
8
soluble
No
y1951
22125843
sodB
superoxide dismutase [Yersinia pestis KI...
206
other biological interest /
iron-regulated oxidative stress enzyme
Community Requests
1ISA
75.2%
Yersinia pestis
IDP91013
(
show subtarget assignments
)
8
selected
No
y2358
22126242
hmsF
outer membrane N-deacetylase [Yersinia p...
673
interesting protein in the context of biofilm formation in Y pestis
Community Requests
Yersinia pestis
IDP91021
(
show subtarget assignments
)
8
cloned
No
y2872
22126749
yiuR
putative outer membrane receptor [Yersin...
665
other biological interest /
putative iron-binding TonB-dependent outer membrane receptor
Community Requests
2HDF
38%
Yersinia pestis
IDP91207
(
show subtarget assignments
)
8
soluble
No
BT_2842
29348251
3-dehydroquinate dehydratase [Bacteroide...
140
potential drug target /
Shikimate pathway enzyme
Community Requests
2C4W
49%
Bacteroides thetaiotaomicron
IDP04002
(
show subtarget assignments
)
8
selected
No
CAC05806
12329075
ipgA
IpgA, similarities to IpgE, putative cha...
129
Shigella effector protein
Community Requests
Shigella flexneri
IDP91330
(
show subtarget assignments
)
8
soluble
No
VV2_0263
27366712
ABC transporter ATPase [Vibrio vulnificu...
551
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP04060
(
show subtarget assignments
)
8
selected
No
CAC05813
12329082
mxiI
MxiI, component of the Mxi-Spa secretion...
97
Shigella effector protein
Community Requests
Shigella flexneri
IDP04066
(
show subtarget assignments
)
8
selected
No
CAC05819
12329088
mxiE
MxiE, similarities to transcriptional ac...
210
Shigella effector protein
Community Requests
Shigella flexneri
IDP04223
(
show subtarget assignments
)
8
selected
No
CAC05808
12329077
ipgD
IpgD, secreted by the Mxi-Spa machinery,...
538
Shigella effector protein
Community Requests
Shigella flexneri
IDP04222
(
show subtarget assignments
)
8
selected
No
CAC05827
12329096
spa33
Spa33, component of the Mxi-Spa secretio...
293
Shigella effector protein
Community Requests
Shigella flexneri
IDP91331
(
show subtarget assignments
)
8
purified
No
VV2_0244
27366693
hypothetical protein VV2_0244 [Vibrio vu...
121
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
2K54
28.9%
Vibrio vulnificus
IDP04224
(
show subtarget assignments
)
8
selected
No
CAC05802
12329071
ipaC
IpaC, secreted by the Mxi-Spa secretion ...
363
Shigella effector protein
Community Requests
Shigella flexneri
IDP04336
(
show subtarget assignments
)
8
in_crystallization_trials
No
CAC05790
12329059
ospC1
OspC1, secreted by the Mxi-Spa secretion...
470
Shigella effector protein
Community Requests
Shigella flexneri
IDP04326
(
show subtarget assignments
)
8
purified
No
CAC05800
12329069
ipaA
IpaA, secreted by the Mxi-Spa machinery,...
633
Shigella effector protein
Community Requests
2FM8
10.7%
Shigella flexneri
IDP04381
(
show subtarget assignments
)
8
selected
No
CAC05791
12329060
unnamed protein product [Shigella flexne...
296
Shigella effector protein
Community Requests
3MKL
8.4%
Shigella flexneri
IDP04414
(
show subtarget assignments
)
8
selected
No
CAC05786
12329055
sepA
SepA, extracellular serine protease of t...
1364
Shigella effector protein
Community Requests
1WXR
34.9%
Shigella flexneri
IDP04536
(
show subtarget assignments
)
8
selected
No
CAC05826
12329095
spa32
Spa32, secreted by and component of the ...
292
Shigella effector protein
Community Requests
Shigella flexneri
IDP04535
(
show subtarget assignments
)
8
selected
No
CAC05816
12329085
mxiN
MxiN, putative component of the Mxi-Spa ...
231
Shigella effector protein
Community Requests
Shigella flexneri
IDP04538
(
show subtarget assignments
)
8
in_crystallization_trials
No
CAC05770
12329039
ospB
OspB, protein secreted by the Mxi-Spa se...
288
Shigella effector protein
Community Requests
Shigella flexneri
IDP04537
(
show subtarget assignments
)
8
selected
No
CAC05780
12329049
virF
VirF, member of the AraC family of trans...
262
Shigella effector protein
Community Requests
3GBG
26.3%
Shigella flexneri
IDP04559
(
show subtarget assignments
)
8
selected
No
CAC05871
12329140
ospE1
OspE1, secreted by the Mxi-Spa secretion...
88
Shigella effector protein
Community Requests
Shigella flexneri
IDP04558
(
show subtarget assignments
)
8
selected
No
CAC05811
12329080
mxiG
MxiG, component of the Mxi-Spa secretion...
371
Shigella effector protein
Community Requests
4A4Y
34%
Shigella flexneri
IDP04627
(
show subtarget assignments
)
8
cloned
No
BAS5321
49188305
replicative DNA helicase [Bacillus anthr...
453
Proposed to be essential proteins
Community Requests
2VYE
75.3%
Bacillus anthracis
IDP90000
(
show subtarget assignments
)
8
cloned
No
FTT1352
56708408
hypothetical protein FTT1352
383
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Francisella tularensis
IDP90081
(
show subtarget assignments
)
8
cloned
No
ABD79034.1
89892477
M2
matrix protein 2 [Influenza A virus (A/U...
96
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2L0J
42.7%
Influenza A
IDP90007
(
show subtarget assignments
)
8
cloned
No
Z4378
12517596
qseC
quorum sensing Escherichia coli regulato...
449
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3JZ3
47%
Escherichia coli
IDP90082
(
show subtarget assignments
)
8
purified
No
P03493.2
85681917
RecName: Full=Matrix protein 2; AltName:...
109
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2KJ1
64.2%
Influenza B
IDP90083
(
show subtarget assignments
)
8
cloned
No
ZP_01795671
145640077
hypothetical protein CGSHiII_00664 [Haem...
219
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
35.6%
Haemophilus influenzae
IDP90086
(
show subtarget assignments
)
8
expressed
No
ZZZ_0002
492
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90087
(
show subtarget assignments
)
8
cloned
No
ZZZ_0003
168
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90089
(
show subtarget assignments
)
8
expressed
No
ZZZ_0005
600
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90090
(
show subtarget assignments
)
8
expressed
No
ZZZ_0006
310
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90097
(
show subtarget assignments
)
8
cloned
No
ZZZ_0013
104
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90096
(
show subtarget assignments
)
8
expressed
No
ZZZ_0012
476
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90099
(
show subtarget assignments
)
8
cloned
No
ZZZ_0015
1137
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90098
(
show subtarget assignments
)
8
purified
No
ZZZ_0014
196
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
3U66
19.4%
Escherichia coli
IDP90102
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_002
68449079
TNF-alpha-receptor-like protein [Monkeyp...
348
similar to VACV-COP-C22L/B28R, MPXV-ZAI96-J2L/J2R
Community Requests
3ON9
23.6%
Monkeypox virus
IDP90101
(
show subtarget assignments
)
8
in_crystallization_trials
No
STM2287
16765614
sseL
deubiquitinase [Salmonella typhimurium L...
317
SseL, is a ubiquitin isopeptidase that plays a critical role in the virulence an...
Community Requests
Salmonella enterica
IDP90103
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_003
68449080
ankyrin-like protein [Monkeypox virus]
587
similar to VACV-COP-B25R/C19L, MPXV-ZAI96-J3L/J1R
Community Requests
Monkeypox virus
IDP90104
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_004
68449081
ankyrin-like protein [Monkeypox virus]
437
similar to CPXV-GRI-C1L, MPXV-ZAI96-D1L/N4R
Community Requests
2Y1L
9.6%
Monkeypox virus
IDP90109
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_014
68449088
interleukin-18-binding protein [Monkeypo...
126
similar to VACWR-C12L,VARV-BSH75_banu-D7L, MPXV-ZAI96-D6L
Community Requests
3F62
79.4%
Monkeypox virus
IDP90108
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_013
68449087
bifunctional zinc finger-like protein/E3...
242
similar to VARV BEN68-zinc finger-like protein
Community Requests
2ECW
8.3%
Monkeypox virus
IDP90110
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_015
68449089
ankyrin-like protein [Monkeypox virus]
660
similar to CPXV-GRI-C9L,CPXV-BR-V024, MPXV-ZAI96-D7L
Community Requests
1N0Q
4.4%
Monkeypox virus
IDP90111
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_017
68449091
ankyrin-like protein [Monkeypox virus]
630
similar to VACV-COP-C9L, MPXV-ZAI96-D9L
Community Requests
3NOC
5.1%
Monkeypox virus
IDP90114
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_023
68449097
kelch-like protein [Monkeypox virus]
105
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
Monkeypox virus
IDP90115
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_024
68449098
kelch-like protein [Monkeypox virus]
176
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
2XN4
26.1%
Monkeypox virus
IDP90117
(
show subtarget assignments
)
8
in_crystallization_trials
No
MPXV_ZAI1979_005_027
68449101
virokine protein [Monkeypox virus]
117
similar to VACV-COP-N1L, MPXV-ZAI96-P1L
Community Requests
2I39
89.7%
Monkeypox virus
IDP90118
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_028
68449102
alpha-amanitin target protein [Monkeypox...
177
similar to VACV-COP-N2L, MPXV-ZAI96-P2L
Community Requests
Monkeypox virus
IDP90124
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_036
68449110
unknown [Monkeypox virus]
219
mitochondrial-associated inhibitor of apoptosis, similar to VACV-COP-F1L, MPXV-Z...
Community Requests
2VTY
69.4%
Monkeypox virus
IDP90123
(
show subtarget assignments
)
8
in_crystallization_trials
No
MPXV_ZAI1979_005_035
68449109
B15R-like protein [Monkeypox virus]
149
similar to VACV-COP-K7R, MPXV-ZAI96-C6R
Community Requests
2K36
94%
Monkeypox virus
IDP90125
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_038
68449112
kelch-like protein [Monkeypox virus]
485
similar to VACV-COP-F3L, MPXV-ZAI96-C9L
Community Requests
1ZGK
13.6%
Monkeypox virus
IDP90126
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_044
68449118
unknown [Monkeypox virus]
212
thiol substrate, similar to VACV-COP-F9L, MPXV-ZAI96-C15L
Community Requests
1YPY
21.7%
Monkeypox virus
IDP90130
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_133
68449207
soluble myristylprotein [Monkeypox virus...
377
similar to VACV-COP-A16L, MPXV-ZAI96-A17L
Community Requests
Monkeypox virus
IDP90129
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_084
68449158
myristylprotein [Monkeypox virus]
340
similar to VACV-COP-G9R, MPXV-ZAI96-G10R
Community Requests
Monkeypox virus
IDP90131
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_144
68449218
cowpox A-type inclusion protein [Monkeyp...
67
similar to part of CPXV-GRI-A26L
Community Requests
Monkeypox virus
IDP90132
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_155
68449229
unknown [Monkeypox virus]
176
similar to VACV-COP-A35R, MPXV-ZAI96-A37R
Community Requests
Monkeypox virus
IDP90137
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_179
68449250
ankyrin-like protein [Monkeypox virus]
561
similar to VACV-COP-B4R, MPXV-ZAI96-B5R
Community Requests
1N11
11.2%
Monkeypox virus
IDP90136
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_177
68449248
ser/thr kinase [Monkeypox virus]
299
essential for viral DNA replication, similar to VACV-COP-B1R, MPXV-ZAI96-B3R
Community Requests
2V62
40.4%
Monkeypox virus
IDP90138
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_181
68449252
ankyrin-like protein [Monkeypox virus]
119
similar to VACV-COP-B6R, MPXV-ZAI96-B7R
Community Requests
Monkeypox virus
IDP90139
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_182
68449253
bifunctional 21kDa precursor protein of ...
182
virulence, ER resident, similar to VACV-COP-B7R, N-terminal signal peptide, bifu...
Community Requests
Monkeypox virus
IDP90142
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_188
68449259
unknown [Monkeypox virus]
149
similar to VACV-COP-B15R, MPXV-ZAI96-B13R
Community Requests
2VVY
93.3%
Monkeypox virus
IDP90143
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_189
68449260
bifunctional IL-1-beta-inhibitor/prevent...
210
contains IG fold, similar to VACV-WR-197, MPXV-ZAR_1979_005-184
Community Requests
3O4O
29.5%
Monkeypox virus
IDP90145
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_192
68449264
IFN-alpha/beta-receptor-like secreted gl...
352
similar to VACV-COP-B19R, MPXV-ZAI96-B16R
Community Requests
3OQ3
83.2%
Monkeypox virus
IDP90146
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_193
68449265
ankyrin-like protein [Monkeypox virus]
789
similar to VACV-COP-B20R, MPXV-ZAI96-B17R
Community Requests
1MJ0
5.2%
Monkeypox virus
IDP00624
(
show subtarget assignments
)
8
in_pdb
3T41
3QFH
No
SACOL1874
57284795
epiP
epidermin leader peptide processing seri...
457
Drug Target Function
Community Requests
3QFH
94.1%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP90163
(
show subtarget assignments
)
8
in_pdb
3JS3
No
CD2217
172044608
aroD
3-dehydroquinate dehydratase (3-dehydroq...
255
Potential drug target. Shikimate pathway enzyme
Community Requests
3JS3
100%
Clostridium difficile
IDP90165
(
show subtarget assignments
)
8
purified
No
CD1834
123174271
3-phosphoshikimate 1-carboxyvinyltransfe...
437
Potential drug target. Shikimate pathway enzyme
Community Requests
3NVS
32.5%
Clostridium difficile
IDP90164
(
show subtarget assignments
)
8
purified
No
CD1832
122973876
Putative chorismate biosynthesis-related...
337
Potential drug target. Shikimate pathway enzyme
Community Requests
1RZM
47.2%
Clostridium difficile
IDP90169
(
show subtarget assignments
)
8
expressed
No
AAM13454.1
20152993
CPXV008 CDS
CPXV008 protein
672
Potential drug target. Shikimate pathway enzyme
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90167
(
show subtarget assignments
)
8
purified
No
CD1838
123066836
Shikimate kinase
177
Potential drug target. Shikimate pathway enzyme
Community Requests
2PT5
31.6%
Clostridium difficile
IDP90170
(
show subtarget assignments
)
8
selected
No
AAM13458.1
20152997
CPXV011 CDS
CPXV011 protein
658
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90171
(
show subtarget assignments
)
8
cloned
No
AAM13460.1
20152999
CPXV013 CDS
CPXV013 protein
523
kelch-like protein
Community Requests
3HVE
10.1%
Cowpox virus
conserved hypothetical proteins
0
IDP90176
(
show subtarget assignments
)
8
expressed
No
AAM13470.1
20153009
CPXV023 CDS
CPXV023 protein
242
zinc-finger-like protein
Community Requests
2ECW
8.3%
Cowpox virus
host defense modulator
0
IDP90175
(
show subtarget assignments
)
8
expressed
No
AAM13468.1
20153007
VGF
CPXV021 protein or CPXV VGF protein
139
similar to viral growth factor C11R vaccinia virus
Community Requests
1K36
15.8%
Cowpox virus
host range protein
0
IDP90177
(
show subtarget assignments
)
8
expressed
No
AAM13471.1
20153010
CPXV024 CDS
CPXV024 protein
126
Orthopoxvirus interleukin 18 binding protein; plays a key role in the activation...
Community Requests
3F62
80.2%
Cowpox virus
host defense modulator
0
IDP90178
(
show subtarget assignments
)
8
purified
No
AAM13472.1
20153011
VHR1
VHR1 or CPXV025 protein
668
ankyrin-like protein, CP77
Community Requests
1N11
10%
Cowpox virus
host range protein
0
IDP91333
(
show subtarget assignments
)
8
in_crystallization_trials
No
VV2_0175
27366631
hypothetical protein VV2_0175 [Vibrio vu...
86
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP91332
(
show subtarget assignments
)
8
purified
No
VV2_0201
27366656
DNA-binding transcriptional regulator Fr...
326
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
3O74
39%
Vibrio vulnificus
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