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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 13 of 60, showing 100 records out of 5973 total, starting on record 1201
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP91002
(
show subtarget assignments
)
8
selected
No
y1919
22125812
bifunctional UDP-glucuronic acid decarbo...
667
virulence/pathogenesis /
-
Community Requests
1Z7E
70.2%
Yersinia pestis
IDP91485
(
show subtarget assignments
)
8
cloned
No
VP1699
28898473
transcriptional regulator ExsA [Vibrio p...
286
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
3MKL
10.8%
Vibrio parahaemolyticus
IDP91751
(
show subtarget assignments
)
8
selected
No
STRP_STREQ
0
440
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1BML
81.1%
Streptococcus dysgalactiae
IDP91279
(
show subtarget assignments
)
8
soluble
No
NT05BA4913
49181643
DNA-binding response regulator [Bacillus...
231
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2OQR
32%
Bacillus anthracis
IDP04005
(
show subtarget assignments
)
1
purified
No
BAS4355
49187350
valyl-tRNA synthetase [Bacillus anthraci...
881
Proposed to be essential proteins
Phase 4: April 2009
1GAX
42.6%
Bacillus anthracis
IDP05046
(
show subtarget assignments
)
1
expressed
No
BA_3529
30258064
hypothetical protein BA_3529 [Bacillus a...
117
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91486
(
show subtarget assignments
)
8
cloned
No
VP1698
28898472
hypothetical protein VP1698 [Vibrio para...
332
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP91004
(
show subtarget assignments
)
8
soluble
No
y1935
22125827
cysteine desulfurase activator complex s...
503
potential drug target /
part of iron-sulfur cluster assembly system active under stress conditions
Community Requests
4DN7
18.7%
Yersinia pestis
IDP91487
(
show subtarget assignments
)
8
soluble
No
VP1697
28898471
putative type III export apparatus prote...
142
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
1XKP
20.4%
Vibrio parahaemolyticus
IDP04003
(
show subtarget assignments
)
1
cloned
No
BAS0126
49183160
50S ribosomal protein L18 [Bacillus anth...
120
Proposed to be essential proteins
Phase 4: April 2009
1OVY
75.8%
Bacillus anthracis
IDP91750
(
show subtarget assignments
)
8
selected
No
SPG2_STRSG
0
593
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2KN4
12.1%
Streptococcus sp.
IDP04002
(
show subtarget assignments
)
8
selected
No
CAC05806
12329075
ipgA
IpgA, similarities to IpgE, putative cha...
129
Shigella effector protein
Community Requests
Shigella flexneri
IDP91489
(
show subtarget assignments
)
8
cloned
No
VP1694
28898468
type III export protein YscF [Vibrio par...
82
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
2P58
51.2%
Vibrio parahaemolyticus
IDP91001
(
show subtarget assignments
)
8
soluble
No
y1897
22125790
yfeA
periplasmic-binding protein [Yersinia pe...
323
virulence/pathogenesis /
periplasmic iron-binding protein
Community Requests
1XVL
52.9%
Yersinia pestis
IDP91015
(
show subtarget assignments
)
8
selected
No
y2404
22126288
psn
pesticin/yersiniabactin outer membrane r...
673
TonB-dependent outer membrane receptor (yersiniabactin-binding)
Community Requests
1NQF
23.8%
Yersinia pestis
IDP05677
(
show subtarget assignments
)
1
in_pdb
4EAE
No
lmo1068
16803108
-
hypothetical protein lmo1068 [Listeria m...
286
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
4EAE
65.4%
Listeria monocytogenes
IDP91553
(
show subtarget assignments
)
8
expressed
No
BAB38471
13364525
ECs5048
hypothetical protein [Escherichia coli O...
430
virulence/pathogenesis /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2J8K
10.5%
Escherichia coli
IDP91367
(
show subtarget assignments
)
8
expressed
No
VV1_2638
27365931
NAD-specific glutamate dehydrogenase [Vi...
789
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP91007
(
show subtarget assignments
)
8
expressed
No
y1938
22125830
bifunctional cysteine desulfurase/seleno...
410
potential drug target /
part of iron-sulfur cluster assembly system active under stress conditions
Community Requests
1I29
69.8%
Yersinia pestis
IDP91494
(
show subtarget assignments
)
8
purified
No
VP1691
28898465
type III export protein [Vibrio parahaem...
114
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP04022
(
show subtarget assignments
)
1
cloned
No
BAS0095
49183129
preprotein translocase subunit SecE [Bac...
59
Proposed to be essential proteins
Phase 4: April 2009
3DIN
33.9%
Bacillus anthracis
IDP91369
(
show subtarget assignments
)
8
in_pdb
4DB3
No
VV1_2570
326424042
N-acetyl-D-glucosamine kinase [Vibrio vu...
303
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
4DB3
100%
Vibrio vulnificus
IDP05094
(
show subtarget assignments
)
1
purified
No
BA_3160
30257733
hypothetical protein BA_3160 [Bacillus a...
257
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04021
(
show subtarget assignments
)
1
expressed
No
BAS3695
49186694
30S ribosomal protein S16 [Bacillus anth...
90
Proposed to be essential proteins
Phase 4: April 2009
1EMW
42.2%
Bacillus anthracis
IDP04604
(
show subtarget assignments
)
1
cloned
No
BAS3678
49186677
30S ribosomal protein S2 [Bacillus anthr...
233
Proposed to be essential proteins
Phase 4: April 2009
1FJG
56.2%
Bacillus anthracis
IDP91167
(
show subtarget assignments
)
8
expressed
No
STM3401
16766690
aroE
shikimate 5-dehydrogenase
272
potential drug target /
Shikimate pathway enzyme
Community Requests
1NYT
84.9%
Salmonella enterica
IDP04013
(
show subtarget assignments
)
1
cloned
No
STM2913_1_498
16766219
putative permease [Salmonella typhimuriu...
498
Salmonella essential protein
Phase 4: April 2009
Salmonella enterica
IDP91496
(
show subtarget assignments
)
8
expressed
No
VP1688
28898462
type III secretion system protein [Vibri...
212
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP91510
(
show subtarget assignments
)
8
cloned
No
VP1664
28898438
putative type III secretion protein [Vib...
126
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP91005
(
show subtarget assignments
)
8
soluble
No
y1936
22125828
ATP-binding component of a transport sys...
257
potential drug target /
part of iron-sulfur cluster assembly system active under stress conditions
Community Requests
2ZU0
80.9%
Yersinia pestis
IDP91273
(
show subtarget assignments
)
8
soluble
No
NT05BA4146
49180892
conserved hypothetical protein TIGR00281...
190
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2Z99
32.1%
Bacillus anthracis
IDP04025
(
show subtarget assignments
)
1
expressed
No
YPCD1.36c
16082724
yscX
hypothetical protein YPCD1.36c [Yersinia...
122
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP04024
(
show subtarget assignments
)
1
cloned
No
BAS5319
49188303
DNA-binding response regulator YycF [Bac...
235
Proposed to be essential proteins
Phase 4: April 2009
2OQR
47.7%
Bacillus anthracis
IDP91498
(
show subtarget assignments
)
8
expressed
No
VP1675
28898449
translocation protein in type III secret...
351
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
2JLH
26.2%
Vibrio parahaemolyticus
IDP91009
(
show subtarget assignments
)
8
soluble
No
y2136
22126024
hypothetical protein y2136 [Yersinia pes...
317
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP04028
(
show subtarget assignments
)
1
purified
No
BAS0109
49183143
30S ribosomal protein S10 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1P6G
61.8%
Bacillus anthracis
IDP91008
(
show subtarget assignments
)
8
soluble
No
y1951
22125843
sodB
superoxide dismutase [Yersinia pestis KI...
206
other biological interest /
iron-regulated oxidative stress enzyme
Community Requests
1ISA
75.2%
Yersinia pestis
IDP91500
(
show subtarget assignments
)
8
cloned
No
VP1673
28898447
translocation protein in type III secret...
88
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP91504
(
show subtarget assignments
)
8
cloned
No
VP1670
28898444
putative translocation protein in type I...
446
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP91501
(
show subtarget assignments
)
8
cloned
No
VP1674
28898448
translocation protein in type III secret...
261
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP91503
(
show subtarget assignments
)
8
soluble
No
VP1671
28898445
type III secretion system protein [Vibri...
328
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
3UEP
9.8%
Vibrio parahaemolyticus
IDP91502
(
show subtarget assignments
)
8
expressed
No
VP1672
28898446
type III secretion system protein [Vibri...
216
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP04026
(
show subtarget assignments
)
1
expressed
No
FTT0456c
56707598
hypothetical protein FTT_0456c [Francise...
97
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1YHD
39.2%
Francisella tularensis
IDP04027
(
show subtarget assignments
)
1
cloned
No
BAS4637
49187628
leucyl-tRNA synthetase [Bacillus anthrac...
802
Proposed to be essential proteins
Phase 4: April 2009
1H3N
45.9%
Bacillus anthracis
IDP91506
(
show subtarget assignments
)
8
expressed
No
VP1668
28898442
type III secretion system ATPase [Vibrio...
440
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
2DPY
44.1%
Vibrio parahaemolyticus
IDP91505
(
show subtarget assignments
)
8
soluble
No
VP1669
28898443
putative type III secretion protein YscO...
153
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP04350
(
show subtarget assignments
)
1
cloned
No
STM1338_1_795
16764689
pheT
phenylalanyl-tRNA synthetase subunit bet...
795
Salmonella essential protein
Phase 4: April 2009
3PCO
92.6%
Salmonella enterica
IDP91014
(
show subtarget assignments
)
8
expressed
No
y2368
22126252
periplasmic protein [Yersinia pestis KIM...
137
other biological interest /
putative iron transport protein
Community Requests
3NRP
92.7%
Yersinia pestis
IDP91352
(
show subtarget assignments
)
8
cloned
No
VV1_3095
27366363
electron transport complex protein RnfC ...
919
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP91039
(
show subtarget assignments
)
8
selected
No
Sd1012_5151
194431100
hdeB
HdeB protein [Shigella dysenteriae 1012]...
108
potential drug target /
A protein that is important for acid resistance in some enteropathogens; it is a...
Community Requests
2XUV
65.7%
Shigella dysenteriae
IDP91010
(
show subtarget assignments
)
8
cloned
No
y2245
22126131
hypothetical protein y2245 [Yersinia pes...
341
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3ETN
12.3%
Yersinia pestis
IDP91512
(
show subtarget assignments
)
8
cloned
No
VV2_0404
27366843
cytolysin [Vibrio vulnificus CMCP6]
468
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
1XEZ
25.9%
Vibrio vulnificus
IDP91514
(
show subtarget assignments
)
8
expressed
No
VV2_1517
27367864
agglutination protein [Vibrio vulnificus...
436
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
1YC9
16.5%
Vibrio vulnificus
IDP05675
(
show subtarget assignments
)
1
purified
No
lmo0953
16802993
-
hypothetical protein lmo0953 [Listeria m...
75
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP04034
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0128
49183162
50S ribosomal protein L30 [Bacillus anth...
60
Proposed to be essential proteins
Phase 4: April 2009
1VS6
53.3%
Bacillus anthracis
IDP91011
(
show subtarget assignments
)
8
purified
No
y2255
22126141
hypothetical protein y2255 [Yersinia pes...
251
other biological interest /
possibly involved in quorum sensing
Community Requests
1KON
83.3%
Yersinia pestis
IDP91522
(
show subtarget assignments
)
8
selected
No
TGGT1_033230
221484314
conserved hypothetical protein [Toxoplas...
610
potential drug target /
Identified in yeast two-hybrid screen with MORN1 as bait and named MIP1 for MORN...
Community Requests
Toxoplasma gondii
IDP91521
(
show subtarget assignments
)
8
selected
No
TGME49_040910
237834825
C2 domain-containing protein [Toxoplasma...
1990
potential drug target; virulence/pathogenesis /
DOC2.1 was identified in a temperature sensitive host cell invasion/egress mutan...
Community Requests
Toxoplasma gondii
IDP91526
(
show subtarget assignments
)
8
in_crystallization_trials
No
lpg1815
52842042
oxyR
hydrogen peroxide-inducible genes activa...
296
other biological interest /
The Legionella pneumophila OxyR is a member of the LysR family that is no longer...
Community Requests
1I6A
28.4%
Legionella pneumophila
IDP91524
(
show subtarget assignments
)
8
selected
No
TGME49_046110
237835443
hypothetical protein TGME49_046110 [Toxo...
386
potential drug target /
Paralog of MIP1 (=MORN1 Interacting Protein 1 or MIP1; GI 237838237) and MLP2 (=...
Community Requests
Toxoplasma gondii
IDP91528
(
show subtarget assignments
)
8
in_crystallization_trials
No
lpg1841
52629179
com1
27 kDa outer membrane protein [Legionell...
261
virulence/pathogenesis /
Lpg1841 is most closely related to the major antigen of Coxiella burnetti, and o...
Community Requests
3GYK
25.7%
Legionella pneumophila
IDP91527
(
show subtarget assignments
)
8
cloned
No
AAX13509
89214483
etpA
EtpA [Escherichia coli ETEC H10407]
1767
virulence/pathogenesis /
The EtpA ETEC two-partner secretion (TPS) exoprotein [PMID: 16552055] is a highl...
Community Requests
3AK5
11.2%
Escherichia coli
IDP04349
(
show subtarget assignments
)
1
expressed
No
STM0557_1_550
16763935
putative inner membrane protein [Salmone...
550
Salmonella essential protein
Phase 4: April 2009
Salmonella enterica
IDP91013
(
show subtarget assignments
)
8
selected
No
y2358
22126242
hmsF
outer membrane N-deacetylase [Yersinia p...
673
interesting protein in the context of biofilm formation in Y pestis
Community Requests
Yersinia pestis
IDP91532
(
show subtarget assignments
)
8
selected
No
TC_0728
7190757
omcA
OmcA [Chlamydia muridarum Nigg]
88
vaccine candidate /
Vaccine formulation
Community Requests
Chlamydia muridarum
IDP91533
(
show subtarget assignments
)
8
selected
No
TC_0727
7190756
omcB
OmcB [Chlamydia muridarum Nigg]
554
vaccine candidate /
Vaccine formulation
Community Requests
Chlamydia muridarum
IDP04030
(
show subtarget assignments
)
1
cloned
No
YPO2532
115348229
hypothetical protein [Yersinia pestis CO...
70
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP91536
(
show subtarget assignments
)
0
work_stopped
No
SAR1057
49483247
ptsI
phosphoenolpyruvate-protein phosphotrans...
572
potential drug target /
Protein is a proposed to be a S. aureus (MRSA252) drug target and having crystal...
Community Requests
2WQD
99%
Staphylococcus aureus
IDP91538
(
show subtarget assignments
)
8
in_pdb
4E4R
No
SAR0594
49482818
eutD
phosphotransacetylase [Staphylococcus au...
328
potential drug target /
Protein is a proposed to be a S. aureus (MRSA252) drug target and having crystal...
Community Requests
4E4R
100%
Staphylococcus aureus
IDP91537
(
show subtarget assignments
)
8
in_crystallization_trials
No
SAR1789
49483952
ackA
acetate kinase [Staphylococcus aureus su...
400
potential drug target /
Protein is a proposed to be a S. aureus (MRSA252) drug target and having crystal...
Community Requests
2IIR
56%
Staphylococcus aureus
IDP91543
(
show subtarget assignments
)
8
selected
No
TGME49_057080
237831315
cAMP-specific 3',5'-cyclic phosphodieste...
1691
potential drug target /
Phosphodiesterases are key regulators of cell signalling pathways and are attrac...
Community Requests
3ECM
6.6%
Toxoplasma gondii
IDP91551
(
show subtarget assignments
)
8
cloned
No
CPF_1456
110799663
hypothetical protein CPF_1456 [Clostridi...
851
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Clostridium perfringens
IDP91542
(
show subtarget assignments
)
8
selected
No
TGME49_080410
237844275
3',5'-cyclic phosphodiesterase, putative...
1085
potential drug target /
Phosphodiesterases are key regulators of cell signalling pathways and are attrac...
Community Requests
1SO2
11.2%
Toxoplasma gondii
IDP91541
(
show subtarget assignments
)
8
selected
No
TGME49_118680
237841017
3',5'--cyclic-nucleotide phosphodiestera...
812
potential drug target /
Phosphodiesterases are key regulators of cell signalling pathways and are attrac...
Community Requests
3QI3
13.8%
Toxoplasma gondii
IDP91545
(
show subtarget assignments
)
8
expressed
No
AAC78336
3892237
ereA2
erythromycin esterase [Providencia stuar...
408
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Providencia stuartii
IDP91544
(
show subtarget assignments
)
8
in_crystallization_trials
No
BAE54319
83627318
ereB
erythromycin esterase type II [Escherich...
419
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2QGM
25.8%
Escherichia coli
IDP91546
(
show subtarget assignments
)
8
in_pdb
4E8L
No
AAA26683
398085
vat
acetyltransferase [Staphylococcus aureus...
219
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
4E8L
100%
Staphylococcus aureus
IDP91547
(
show subtarget assignments
)
8
selected
No
EfaeDRAFT_0205
69249189
Protein of unknown function DUF470:Prote...
866
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Enterococcus faecium
IDP91356
(
show subtarget assignments
)
8
cloned
No
VV1_2923
27366200
DNA-binding protein H-NS [Vibrio vulnifi...
135
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
1OV9
31.1%
Vibrio vulnificus
IDP04367
(
show subtarget assignments
)
1
cloned
No
BAS3563
49186564
PTS system, fructose-specific IIABC comp...
622
Proposed to be essential proteins
Phase 4: April 2009
2R4Q
11.4%
Bacillus anthracis
IDP91020
(
show subtarget assignments
)
8
in_crystallization_trials
No
y2842
22126718
hypothetical protein y2842 [Yersinia pes...
378
other biological interest /
putative periplasmic iron-binding protein
Community Requests
2ETV
22.8%
Yersinia pestis
IDP91169
(
show subtarget assignments
)
8
in_pdb
3TNL
3TOZ
No
lmo0490
16802533
-
similar to shikimate 5-dehydrogenase
291
potential drug target /
Shikimate pathway enzyme
Community Requests
3TNL
100%
Listeria monocytogenes
IDP04622
(
show subtarget assignments
)
1
soluble
No
BAS4556
49187550
tyrosyl-tRNA synthetase [Bacillus anthra...
418
potential drug target /
Proposed to be essential proteins
Phase 4: April 2009
2TS1
70.6%
Bacillus anthracis
IDP04596
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS1099
49184119
tryptophanyl-tRNA synthetase [Bacillus a...
329
Proposed to be essential proteins
Phase 4: April 2009
3PRH
73.9%
Bacillus anthracis
IDP04610
(
show subtarget assignments
)
1
in_pdb
3RFO
No
BAS3717
49186716
methionyl-tRNA formyltransferase [Bacill...
314
Proposed to be essential proteins
Phase 4: April 2009
3RFO
100%
Bacillus anthracis
IDP91370
(
show subtarget assignments
)
8
expressed
No
VV1_2349
27365668
lactonizing lipase [Vibrio vulnificus CM...
302
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
1EX9
55%
Vibrio vulnificus
IDP04380
(
show subtarget assignments
)
1
cloned
No
STM3713_1_404
16766998
rfaL
O-antigen ligase [Salmonella typhimurium...
404
Salmonella essential protein
Phase 4: April 2009
Salmonella enterica
IDP91561
(
show subtarget assignments
)
8
purified
No
BAB33895
13359929
ECs0472
hypothetical protein [Escherichia coli O...
523
virulence/pathogenesis /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Escherichia coli
IDP91038
(
show subtarget assignments
)
8
cloned
No
SAHV_2481
156980811
hypothetical protein SAHV_2481 [Staphylo...
1115
drug resistance /
SasG is a highly interesting multi-domain protein involved in biofilm formation ...
Community Requests
3TIQ
18.7%
Staphylococcus aureus
IDP91558
(
show subtarget assignments
)
8
in_crystallization_trials
No
BAB38076
13364128
ECs4653
hypothetical protein [Escherichia coli O...
802
virulence/pathogenesis /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Escherichia coli
IDP91560
(
show subtarget assignments
)
8
purified
No
BAB33496
13359529
ECs0073
hypothetical protein [Escherichia coli O...
189
virulence/pathogenesis /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Escherichia coli
IDP04066
(
show subtarget assignments
)
8
selected
No
CAC05819
12329088
mxiE
MxiE, similarities to transcriptional ac...
210
Shigella effector protein
Community Requests
Shigella flexneri
IDP05162
(
show subtarget assignments
)
1
soluble
No
BA_1701
30255991
hypothetical protein BA_1701 [Bacillus a...
225
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04046
(
show subtarget assignments
)
1
cloned
No
YPCD1.78c
16082765
tap
repA translation protein [Yersinia pesti...
24
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP91179
(
show subtarget assignments
)
8
expressed
No
y2283
22126168
hypothetical protein y2283 [Yersinia pes...
291
other biological interest /
Other biological interest
Community Requests
2PZ0
24.7%
Yersinia pestis
IDP04357
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT0894
56707995
purCD
fusion protein PurC/PurD [Francisella tu...
770
conserved gene; putative drug target function;
Phase 4: April 2009
2YRW
20.3%
Francisella tularensis
IDP91294
(
show subtarget assignments
)
8
soluble
No
SPA4035
56416018
hypothetical protein SPA4035 [Salmonella...
279
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Salmonella enterica
IDP05689
(
show subtarget assignments
)
1
cloned
No
lmo1654
16803694
-
putative cellsurface protein [Listeria m...
164
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP92554
(
show subtarget assignments
)
8
selected
No
VV1_1165
27360700
Glycerol-3-phosphate acyltransferase [Vi...
809
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
Vibrio vulnificus
IDP92553
(
show subtarget assignments
)
8
selected
No
VV1_2233
27361706
fadR
fatty acid metabolism transcriptional re...
279
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
1E2X
52%
Vibrio vulnificus
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