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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
In
IDP#
NCBI GI
LOCUS TAG
Search
Page 14 of 60, showing 100 records out of 5973 total, starting on record 1301
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP91664
(
show subtarget assignments
)
8
selected
No
NP_055232
15193488
BBC3
bcl-2-binding component 3 isoform 4 [Hom...
193
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2ROC
12.4%
Homo sapiens
IDP04021
(
show subtarget assignments
)
1
expressed
No
BAS3695
49186694
30S ribosomal protein S16 [Bacillus anth...
90
Proposed to be essential proteins
Phase 4: April 2009
1EMW
42.2%
Bacillus anthracis
IDP91210
(
show subtarget assignments
)
8
expressed
No
BLIJ_0364
189439941
aroG2
phospho-2-dehydro-3-deoxyheptonate aldol...
377
potential drug target /
Shikimate pathway enzyme
Community Requests
1GG1
47.7%
Bifidobacterium longum
IDP05383
(
show subtarget assignments
)
1
purified
No
BA_1433
30255366
hypothetical protein BA_1433 [Bacillus a...
55
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05376
(
show subtarget assignments
)
1
cloned
No
BA_4131
30258637
hypothetical protein BA_4131 [Bacillus a...
44
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04534
(
show subtarget assignments
)
8
selected
No
CAC05815
12329084
mxiK
MxiK, putative component of the Mxi-Spa ...
175
Shigella effector protein
Community Requests
Shigella flexneri
IDP91197
(
show subtarget assignments
)
8
soluble
No
BAS4345
49187340
-
stage IV sporulation protein FA
248
essential/virulence/pathogenesis /
Essential proteins
Community Requests
3TUF
10.9%
Bacillus anthracis
IDP91667
(
show subtarget assignments
)
8
selected
No
POLG_CXB3W
0
2185
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2IJD
20.7%
Coxsackievirus B3
IDP91669
(
show subtarget assignments
)
8
selected
No
AGSK1_HUMAN
0
129
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
Homo sapiens
IDP05378
(
show subtarget assignments
)
1
soluble
No
BA_4133
30258639
hypothetical protein BA_4133 [Bacillus a...
81
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP04525
(
show subtarget assignments
)
1
cloned
No
STM1556_1_483
16764900
putative Na+/H+ antiporter [Salmonella t...
483
Salmonella essential protein
Phase 4: April 2009
Salmonella enterica
IDP04210
(
show subtarget assignments
)
1
expressed
No
ZZZ_0017
243
Effector protein
Phase 4: April 2009
2KXC
18.5%
Escherichia coli
IDP05658
(
show subtarget assignments
)
1
cloned
No
lmo0207
16802253
-
hypothetical protein lmo0207 [Listeria m...
153
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2JOE
34%
Listeria monocytogenes
Viral functions: General
IDP05565
(
show subtarget assignments
)
1
cloned
No
lmo2505
16804543
spl
peptidoglycan lytic protein P45 [Listeri...
401
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2XIV
14%
Listeria monocytogenes
Viral functions: General
IDP05428
(
show subtarget assignments
)
1
cloned
No
lmo0717
16802759
-
hypothetical protein lmo0717 [Listeria m...
222
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Viral functions: General
IDP05267
(
show subtarget assignments
)
1
soluble
No
lmo0255
16802301
-
hypothetical protein lmo0255 [Listeria m...
167
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Viral functions: General
IDP00401
(
show subtarget assignments
)
1
cloned
No
YPO2490
161486873
putative hemolysin
2531
Virulence Associated Factor
Phase 2: March 2008
1RWR
3.9%
Yersinia pestis
Viral functions
General
IDP05717
(
show subtarget assignments
)
1
cloned
No
BA_1098
30254828
wall-associated domain protein [Bacillus...
178
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05636
(
show subtarget assignments
)
1
soluble
No
CD2388
126700003
putative peptidoglycan-binding/hydrolysi...
200
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3BKH
17.5%
Clostridium difficile
Unknown function: General
IDP05605
(
show subtarget assignments
)
1
cloned
No
BA_4978
30259470
collagen triple helix repeat domain prot...
469
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3HQV
27.7%
Bacillus anthracis
Unknown function: General
IDP05583
(
show subtarget assignments
)
1
soluble
No
BA_2249
30256893
SCO1/SenC family lipoprotein [Bacillus a...
195
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1XZO
45.6%
Bacillus anthracis
Unknown function: General
IDP05628
(
show subtarget assignments
)
1
soluble
No
CD1444
126699048
putative exported polysaccharide deacety...
239
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2C1G
32.6%
Clostridium difficile
Unknown function: General
IDP05533
(
show subtarget assignments
)
1
cloned
No
CD2149
126699765
hypothetical protein CD2149 [Clostridium...
419
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Unknown function: General
IDP05534
(
show subtarget assignments
)
1
in_crystallization_trials
No
CD3106
126700723
putative phopho-sugar aldolase [Clostrid...
213
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3R8R
35.2%
Clostridium difficile
Unknown function: General
IDP05502
(
show subtarget assignments
)
1
cloned
No
CD0386
126697956
putative collagen-binding surface protei...
1014
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Unknown function: General
IDP05506
(
show subtarget assignments
)
1
soluble
No
CD1232
126698828
putative lipoprotein [Clostridium diffic...
273
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1NA0
15.8%
Clostridium difficile
Unknown function: General
IDP05461
(
show subtarget assignments
)
1
selected
No
BA_1618
30255916
conserved repeat domain protein [Bacillu...
5017
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05488
(
show subtarget assignments
)
1
cloned
No
BA_4789
30259275
putative LPXTG-motif cell wall anchor do...
237
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2K78
22.8%
Bacillus anthracis
Unknown function: General
IDP05536
(
show subtarget assignments
)
1
cloned
No
CD3145
126700762
putative serine-aspartate-rich surface a...
1190
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1YO8
7.6%
Clostridium difficile
Unknown function: General
IDP05026
(
show subtarget assignments
)
1
cloned
No
BA_0025
30253539
putative csfB protein [Bacillus anthraci...
59
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05538
(
show subtarget assignments
)
1
cloned
No
CD3392
126701015
putative collagen-binding surface protei...
1014
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Unknown function: General
IDP05419
(
show subtarget assignments
)
1
soluble
No
BA_5318
30259794
endonuclease/exonuclease/phosphatase fam...
352
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05737
(
show subtarget assignments
)
1
expressed
No
CD1990
126699598
hypothetical protein CD1990 [Clostridium...
139
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
Clostridium difficile
Unknown function: General
IDP05371
(
show subtarget assignments
)
1
selected
No
BA_3601
30258129
conserved repeat domain protein [Bacillu...
2358
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05028
(
show subtarget assignments
)
1
purified
No
BA_0331
30253869
polysaccharide deacetylase-like protein ...
367
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05329
(
show subtarget assignments
)
1
soluble
No
BA_0815
30254405
purple acid phosphatase/fibronectin doma...
819
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2HY1
6%
Bacillus anthracis
Unknown function: General
IDP05321
(
show subtarget assignments
)
1
cloned
No
CD1857
126699466
putative conjugative transposon cell wal...
720
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2K1G
5%
Clostridium difficile
Unknown function: General
IDP05307
(
show subtarget assignments
)
1
cloned
No
YPO0362
16120697
-
lysyl-tRNA synthetase [Yersinia pestis C...
325
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
3A5Y
84%
Yersinia pestis
Unknown function: General
IDP05312
(
show subtarget assignments
)
1
soluble
No
CD0895
126698472
metallo-beta-lactamase superfamily expor...
304
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Unknown function: General
IDP05249
(
show subtarget assignments
)
1
soluble
No
BAS2289
49185298
-
hypothetical protein BAS2289 [Bacillus a...
512
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05216
(
show subtarget assignments
)
1
cloned
No
CD3349
126700969
bclA3
putative exosporium glycoprotein [Clostr...
657
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3HQV
35.6%
Clostridium difficile
Unknown function: General
IDP05224
(
show subtarget assignments
)
1
cloned
No
VC_0595
9655026
glutamyl-tRNA synthetase-related protein...
304
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1NZJ
55.3%
Vibrio cholerae
Unknown function: General
IDP05169
(
show subtarget assignments
)
1
soluble
No
BA_1952
30256610
NLP/P60 family protein [Bacillus anthrac...
420
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2F68
14%
Bacillus anthracis
Unknown function: General
IDP91086
(
show subtarget assignments
)
8
soluble
No
CBU_0750
29541350
KpsF/GutQ family protein
324
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
33.3%
Coxiella burnetii
Unknown function: General
IDP05143
(
show subtarget assignments
)
1
cloned
No
BAS4423
49187418
-
triple helix repeat-containing collagen ...
312
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1WCK
27.6%
Bacillus anthracis
Unknown function: General
IDP05117
(
show subtarget assignments
)
1
cloned
No
CD2831
126700447
putative collagen-binding protein [Clost...
972
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3KPT
9.3%
Clostridium difficile
Unknown function: General
IDP05113
(
show subtarget assignments
)
1
in_pdb
4EGU
No
CD2447
126700064
histidine triad nucleotide-binding prote...
119
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
4EGU
100%
Clostridium difficile
Unknown function: General
IDP05112
(
show subtarget assignments
)
1
cloned
No
CD2246
126699864
cspC
putative germination-specific protease [...
557
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3EIF
22.3%
Clostridium difficile
Unknown function: General
IDP05053
(
show subtarget assignments
)
1
expressed
No
CD0242
126697813
hypothetical protein CD0242 [Clostridium...
214
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3D5N
18.7%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05059
(
show subtarget assignments
)
1
soluble
No
CD0690
126698269
putative nucleotide phosphodiesterase [C...
655
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3GVE
15.3%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05632
(
show subtarget assignments
)
1
cloned
No
CD1898
126699508
putative phage-related cell wall hydrola...
262
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3QAY
24.4%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05602
(
show subtarget assignments
)
1
cloned
No
BA_4347
30258847
putative lipase/acylhydrolase [Bacillus ...
259
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: Enzymes of unknown specificity
IDP91270
(
show subtarget assignments
)
8
soluble
No
NT05BA3459
49180224
acetyltransf2, N-acetyltransferase [Baci...
217
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3LNB
47.9%
Bacillus anthracis
Unknown function: Enzymes of unknown specificity
IDP91263
(
show subtarget assignments
)
8
soluble
No
NT05BA0394
49177292
pyridine nucleotide-disulfide oxidoreduc...
349
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3LZW
36.4%
Bacillus anthracis
Unknown function: Enzymes of unknown specificity
IDP05535
(
show subtarget assignments
)
1
cloned
No
CD3071
126700688
glycosyl hydrolase [Clostridium difficil...
692
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2XVG
22.3%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05475
(
show subtarget assignments
)
1
expressed
No
BA_2860
30257458
hydrolase, CocE/NonD family [Bacillus an...
597
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1LNS
30.7%
Bacillus anthracis
Unknown function: Enzymes of unknown specificity
IDP05038
(
show subtarget assignments
)
1
expressed
No
BA_1902
30256562
multicopper oxidase family protein [Baci...
551
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3T6V
25.8%
Bacillus anthracis
Unknown function: Enzymes of unknown specificity
IDP05353
(
show subtarget assignments
)
1
cloned
No
CD2903
126700520
putative phage cell wall hydrolase [Clos...
656
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3H41
8.1%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05193
(
show subtarget assignments
)
1
cloned
No
CD0689
126698268
putative nucleotide phosphodiesterase [C...
627
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3GVE
16.4%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05196
(
show subtarget assignments
)
1
cloned
No
CD0961
126698545
putative phage cell wall hydrolase [Clos...
656
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3H41
8.1%
Clostridium difficile
Unknown function: Enzymes of unknown specificity
IDP05166
(
show subtarget assignments
)
1
soluble
No
BA_1921
30256579
amidase family protein [Bacillus anthrac...
536
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1M21
36%
Bacillus anthracis
Unknown function: Enzymes of unknown specificity
IDP04710
(
show subtarget assignments
)
1
selected
No
YPO0510
115346319
hypothetical protein [Yersinia pestis CO...
367
virulence factor; conserved gene;
Phase 4: April 2009
2XT2
14.7%
Yersinia pestis
Unknown function
General
IDP01742
(
show subtarget assignments
)
1
cloned
No
STM3621
16766907
yhjR
putative cytoplasmic protein [Salmonella...
67
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02230
(
show subtarget assignments
)
1
cloned
No
YPO0829
16121138
putative sulfatase [Yersinia pestis CO92...
517
Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...
Phase 3: June 2008
2QZU
40.2%
Yersinia pestis
Unknown function
Enzymes of unknown specificity
IDP02694
(
show subtarget assignments
)
1
soluble
No
STM1325
16764676
ydiZ
putative cytoplasmic protein [Salmonella...
96
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02695
(
show subtarget assignments
)
1
soluble
No
Cj0698
15792047
flgG
flagellar basal body rod protein FlgG [C...
263
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
3A69
23.6%
Campylobacter jejuni
Unknown function
Enzymes of unknown specificity
IDP02707
(
show subtarget assignments
)
1
cloned
No
STM3237
16766536
yhaL
putative cytoplasmic protein [Salmonella...
54
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP00578
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO3553
16123697
elbB
isoprenoid biosynthesis protein with ami...
217
Drug Target Function
Phase 2: March 2008
1OY1
63.6%
Yersinia pestis
Unknown function
General
IDP02237
(
show subtarget assignments
)
1
in_pdb
3T4X
No
GBAA3440
47528725
short chain dehydrogenase/reductase fami...
264
Conserved; Essential;
Phase 3: June 2008
3T4X
100%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP01659
(
show subtarget assignments
)
1
crystallized
No
CBU_1739
29542296
tetrapyrrole (Corrin/Porphyrin) methylas...
285
Conserved; Drug target functions
Phase 3: June 2008
3KWP
42.1%
Coxiella burnetii
Unknown function
General
IDP01737
(
show subtarget assignments
)
1
soluble
No
STM3690
16766975
putative inner membrane lipoprotein [Sal...
227
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01738
(
show subtarget assignments
)
1
cloned
No
STM1484
16764829
putative protease [Salmonella typhimuriu...
273
Drug target motif; Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02675
(
show subtarget assignments
)
1
expressed
No
CBU_1842
29542398
GTP-binding protein YchF [Coxiella burne...
363
Conserved; Drug target functions
Phase 3: June 2008
1JAL
65.3%
Coxiella burnetii
Unknown function
General
IDP02202
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT0774
56707886
hypothetical protein FTT0774 [Francisell...
125
Drug Target
Phase 3: June 2008
3USH
52.8%
Francisella tularensis
Unknown function
General
IDP00560
(
show subtarget assignments
)
1
soluble
No
YPO3852
16123987
hemY
putative protoheme IX biogenesis protein...
406
Conserved Gene / Pathway
Phase 2: March 2008
Yersinia pestis
Unknown function
General
IDP02826
(
show subtarget assignments
)
1
in_crystallization_trials
No
GBAA4254
47529547
transaminase [Bacillus anthracis str. 'A...
392
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
2O1B
40.8%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP01048
(
show subtarget assignments
)
1
in_pdb
3R3S
Yes
STM3157
16766457
yghA
oxidoreductase
294
Conserved Gene / Pathway
Phase 2: March 2008
3R3S
100%
Salmonella enterica
Unknown function
Enzymes of unknown specificity
IDP02658
(
show subtarget assignments
)
1
cloned
No
STM2648
16765968
yfiF
putative methyltransferase [Salmonella t...
345
Conserved; Essential; Drug target functions
Phase 3: June 2008
1X7O
20.6%
Salmonella enterica
Unknown function
General
IDP02656
(
show subtarget assignments
)
1
expressed
No
FTT0558
56707688
short chain dehydrogenase [Francisella t...
203
Drug Target
Phase 3: June 2008
3D7L
41.9%
Francisella tularensis
Unknown function
Enzymes of unknown specificity
IDP01838
(
show subtarget assignments
)
1
cloned
No
STM0941
16764303
ybjY
macrolide transporter subunit MacA [Salm...
372
Conserved; Drug target functions
Phase 3: June 2008
3FPP
79%
Salmonella enterica
Unknown function
General
IDP01833
(
show subtarget assignments
)
1
cloned
No
STM2476
16765796
ypfG
putative periplasmic protein [Salmonella...
347
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01023
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM1051
16764411
sseI
secreted effector protein [Phage Gifsy-2...
322
Virulence Associated Factor
Phase 2: March 2008
3CXB
15.8%
Salmonella enterica
Unknown function
General
IDP01014
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM2780
16766091
pipB2
secreted effector protein
350
Virulence Associated Factor
Phase 2: March 2008
2LEZ
41.4%
Salmonella enterica
Unknown function
General
IDP01747
(
show subtarget assignments
)
1
soluble
No
STM2407
16765733
ypeC
putative periplasmic protein [Salmonella...
108
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01001
(
show subtarget assignments
)
1
soluble
No
STM2405
16765731
indolepyruvate decarboxylase
550
Conserved Gene / Pathway
Phase 2: March 2008
1OVM
66.7%
Salmonella enterica
Unknown function
Enzymes of unknown specificity
IDP02819
(
show subtarget assignments
)
1
expressed
No
STM2414
16765738
yfeD
putative negative regulator [Salmonella ...
130
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02199
(
show subtarget assignments
)
1
expressed
No
CBU_1505
29542064
lepA
GTP-binding protein LepA [Coxiella burne...
614
Conserved; Drug target functions
Phase 3: June 2008
3CB4
69.9%
Coxiella burnetii
Unknown function
General
IDP01723
(
show subtarget assignments
)
1
in_pdb
3KAX
No
GBAA5138
47530443
aminotransferase, classes I and II [Baci...
383
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
3KAX
100%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP02170
(
show subtarget assignments
)
1
soluble
No
FTT1010
56708100
helix-turn-helix family protein [Francis...
67
Drug Target
Phase 3: June 2008
3T75
29.9%
Francisella tularensis
Unknown function
General
IDP01722
(
show subtarget assignments
)
1
soluble
No
STM1881
16765223
yebF
hypothetical protein STM1881 [Salmonella...
117
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02808
(
show subtarget assignments
)
1
cloned
No
STM1084
16764443
yccK
sulfurtransferase TusE [Salmonella typhi...
109
Conserved; Drug target functions
Phase 3: June 2008
1YX3
47.7%
Salmonella enterica
Unknown function
General
IDP02811
(
show subtarget assignments
)
1
soluble
No
STM1880
16765222
yebE
putative inner membrane protein [Salmone...
219
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02163
(
show subtarget assignments
)
1
cloned
No
GBAA3914
47529205
phosphodiesterase [Bacillus anthracis st...
520
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
Bacillus anthracis
Unknown function
General
IDP02609
(
show subtarget assignments
)
1
in_pdb
3LQN
Yes
GBAA4196
47529491
CBS domain-containing protein [Bacillus ...
147
Drug target motif;
Phase 3: June 2008
3LQN
100%
Bacillus anthracis
Unknown function
General
IDP00964
(
show subtarget assignments
)
0
work_stopped
No
STM1439
16764787
ydhF
putative aldo/keto reductase
298
Conserved Gene / Pathway
Phase 2: March 2008
1OG6
88.9%
Salmonella enterica
Unknown function
General
IDP02600
(
show subtarget assignments
)
1
expressed
No
STM2279
16765606
yfaE
2Fe-2S ferredoxin YfaE [Salmonella typhi...
84
Conserved; Drug target functions
Phase 3: June 2008
1IUE
37.2%
Salmonella enterica
Unknown function
General
IDP00957
(
show subtarget assignments
)
0
work_stopped
No
STM1202
16764557
ycfH
predicted metallodependent hydrolase
265
Conserved Gene / Pathway
Phase 2: March 2008
1YIX
92.8%
Salmonella enterica
Unknown function
Enzymes of unknown specificity
IDP02160
(
show subtarget assignments
)
1
soluble
No
CBU_1245
29541815
GTP-binding protein [Coxiella burnetii R...
443
Conserved; Drug target functions
Phase 3: June 2008
2HJG
38.4%
Coxiella burnetii
Unknown function
General
IDP02584
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM1301
16764652
pyrimidine (deoxy)nucleoside triphosphat...
138
Conserved; Drug target functions
Phase 3: June 2008
2RRK
75.4%
Salmonella enterica
Unknown function
General
IDP02587
(
show subtarget assignments
)
1
cloned
No
STM2571
16765891
murQ
N-acetylmuramic acid-6-phosphate etheras...
297
Conserved; Drug target functions
Phase 3: June 2008
1NRI
51.9%
Salmonella enterica
Unknown function
General
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