|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene Name |
Common Name |
Sequence Length |
Selection Phase |
Homolog PDB ID |
Homolog Sequence Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP00565
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO0281 |
16120620 |
hmuT |
hemin-binding periplasmic protein |
279 |
Phase 2: March 2008 |
3MD9
|
91% |
Yersinia pestis |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP01072
(show subtarget assignments)
|
1 |
cloned |
No |
STM4003 |
16767268 |
yihI |
hypothetical protein STM4003 |
171 |
Phase 2: March 2008 |
|
|
Salmonella enterica |
Protein synthesis |
tRNA aminoacylation |
|
|
|
IDP01071
(show subtarget assignments)
|
1 |
in_pdb 3GOA |
Yes |
STM3982 |
16767252 |
fadA |
3-ketoacyl-CoA thiolase |
387 |
Phase 2: March 2008 |
3GOA
|
100% |
Salmonella enterica |
Fatty acid and phospholipid metabolism |
Degradation |
|
|
|
IDP00564
(show subtarget assignments)
|
1 |
selected |
No |
YPO1403 |
16121683 |
mukF |
condesin subunit F |
440 |
Phase 2: March 2008 |
3EUH
|
84.8% |
Yersinia pestis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00563
(show subtarget assignments)
|
1 |
purified |
No |
YPO0283 |
16120622 |
hmuR |
hemin receptor precursor |
676 |
Phase 2: March 2008 |
3FHH
|
66.3% |
Yersinia pestis |
Transport and binding proteins |
Other |
|
|
|
IDP01069
(show subtarget assignments)
|
1 |
soluble |
No |
STM3938 |
16767209 |
hemC |
porphobilinogen deaminase |
318 |
Phase 2: March 2008 |
1AH5
|
87.7% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP01067
(show subtarget assignments)
|
1 |
expressed |
No |
STM3854 |
16767138 |
pstB |
phosphate transporter subunit |
257 |
Phase 2: March 2008 |
2OLJ
|
36.2% |
Salmonella enterica |
Transport and binding proteins |
Anions |
|
|
|
IDP01066
(show subtarget assignments)
|
1 |
expressed |
No |
STM3819 |
16767104 |
ccmA |
heme exporter protein |
205 |
Phase 2: March 2008 |
1Z47
|
32.7% |
Salmonella enterica |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP00561
(show subtarget assignments)
|
0 |
work_stopped |
No |
YPO1046 |
16121346 |
pyrH |
uridylate kinase |
241 |
Phase 2: March 2008 |
2BNE
|
90.5% |
Yersinia pestis |
Purines, pyrimidines, nucleosides, and nucleotides |
Nucleotide and nucleoside interconversions |
|
|
|
IDP00560
(show subtarget assignments)
|
1 |
soluble |
No |
YPO3852 |
16123987 |
hemY |
putative protoheme IX biogenesis protein... |
406 |
Phase 2: March 2008 |
|
|
Yersinia pestis |
Unknown function |
General |
|
|
|
IDP01063
(show subtarget assignments)
|
1 |
soluble |
No |
STM3702 |
16766987 |
grxC |
glutaredoxin 3 |
83 |
Phase 2: March 2008 |
1FOV
|
86.7% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Glutathione and analogs |
|
|
|
IDP01062
(show subtarget assignments)
|
1 |
cloned |
No |
STM3626 |
16766913 |
dppF |
dipeptide transporter ATP-binding subuni... |
337 |
Phase 2: March 2008 |
3DHW
|
27.6% |
Salmonella enterica |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP01061
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM3591 |
16766877 |
uspA |
universal stress protein A |
144 |
Phase 2: March 2008 |
1JMV
|
66.7% |
Salmonella enterica |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP00559
(show subtarget assignments)
|
1 |
purified |
No |
YPO3032 |
16123209 |
hemF |
coproporphyrinogen III oxidase |
309 |
Phase 2: March 2008 |
3E8J
|
59.5% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP01060
(show subtarget assignments)
|
1 |
crystallized |
No |
STM3561 |
16766847 |
livG |
leucine/isoleucine/valine transporter AT... |
255 |
Phase 2: March 2008 |
3FVQ
|
31.6% |
Salmonella enterica |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00558
(show subtarget assignments)
|
1 |
purified |
No |
YPO0654 |
16120979 |
rfaE |
bifunctional heptose 7-phosphate kinase/... |
476 |
Phase 2: March 2008 |
2FV7
|
16.2% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP01058
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM3486 |
16766774 |
aroB |
3-dehydroquinate synthase |
362 |
Phase 2: March 2008 |
3OKF
|
62.4% |
Salmonella enterica |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01057
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM3445 |
16766734 |
tuf |
elongation factor Tu |
394 |
Phase 2: March 2008 |
1D8T
|
99.5% |
Salmonella enterica |
Protein synthesis |
Translation factors |
|
|
|
IDP01056
(show subtarget assignments)
|
1 |
in_pdb 3R3R |
Yes |
STM3399 |
16766688 |
yrdA |
putative ferripyochelin-binding protein ... |
184 |
Phase 2: March 2008 |
3R3R
|
100% |
Salmonella enterica |
Central intermediary metabolism |
Other |
|
|
|
IDP01055
(show subtarget assignments)
|
1 |
crystallized |
No |
STM3371 |
16766666 |
maf |
Maf-like protein |
197 |
Phase 2: March 2008 |
1EX2
|
43.7% |
Salmonella enterica |
Cellular processes |
Cell division |
|
|
|
IDP01054
(show subtarget assignments)
|
1 |
purified |
No |
STM3363 |
16766658 |
yhcO |
putative cytoplasmic protein |
90 |
Phase 2: March 2008 |
2CX6
|
76.7% |
Salmonella enterica |
Protein synthesis |
tRNA aminoacylation |
|
|
|
IDP01053
(show subtarget assignments)
|
1 |
cloned |
No |
STM3330 |
16766625 |
gltB |
glutamate synthase subunit alpha |
1486 |
Phase 2: March 2008 |
1EA0
|
45.2% |
Salmonella enterica |
Central intermediary metabolism |
Other |
|
|
|
IDP00555
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO3424 |
16123573 |
nadC |
quinolinate phosphoribosyltransferase |
302 |
Phase 2: March 2008 |
1QAP
|
72.5% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridine nucleotides |
|
|
|
IDP01052
(show subtarget assignments)
|
1 |
expressed |
No |
STM3324 |
16766619 |
ptsO |
phosphohistidinoprotein-hexose phosphotr... |
90 |
Phase 2: March 2008 |
1JEM
|
34.4% |
Salmonella enterica |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP01050
(show subtarget assignments)
|
1 |
cloned |
No |
STM3201 |
16766501 |
glnE |
bifunctional glutamine-synthetase adenyl... |
947 |
Phase 2: March 2008 |
3K7D
|
47.3% |
Salmonella enterica |
Protein synthesis |
Translation factors |
|
|
|
IDP01049
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM3183 |
16766483 |
icc |
cyclic 3',5'-adenosine monophosphate pho... |
275 |
Phase 2: March 2008 |
2HY1
|
25.1% |
Salmonella enterica |
Central intermediary metabolism |
Other |
|
|
|
IDP01048
(show subtarget assignments)
|
1 |
in_pdb 3R3S |
Yes |
STM3157 |
16766457 |
yghA |
oxidoreductase |
294 |
Phase 2: March 2008 |
3R3S
|
100% |
Salmonella enterica |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP01047
(show subtarget assignments)
|
1 |
cloned |
No |
STM3152 |
16766452 |
|
putative methyl-accepting chemotaxis pro... |
547 |
Phase 2: March 2008 |
3ZX6
|
34.7% |
Salmonella enterica |
Cellular processes |
Chemotaxis and motility |
|
|
|
IDP00552
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0282 |
16120621 |
hmuS |
hemin transport protein |
345 |
Phase 2: March 2008 |
2J0R
|
89.6% |
Yersinia pestis |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP01046
(show subtarget assignments)
|
1 |
expressed |
No |
STM3138 |
16766438 |
|
putative methyl-accepting chemotaxis pro... |
352 |
Phase 2: March 2008 |
1QU7
|
16.8% |
Salmonella enterica |
Cellular processes |
Other |
|
|
|
IDP01045
(show subtarget assignments)
|
1 |
soluble |
No |
STM3114 |
16766415 |
speC |
ornithine decarboxylase isozyme |
711 |
Phase 2: March 2008 |
1ORD
|
53.8% |
Salmonella enterica |
Central intermediary metabolism |
Polyamine biosynthesis |
|
|
|
IDP01044
(show subtarget assignments)
|
1 |
purified |
No |
STM3070 |
16766371 |
epd |
D-erythrose 4-phosphate dehydrogenase |
348 |
Phase 2: March 2008 |
2X5J
|
91.7% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridoxine |
|
|
|
IDP01043
(show subtarget assignments)
|
1 |
soluble |
No |
STM2985 |
16766289 |
ygdK |
putative FeS center assembly protein |
147 |
Phase 2: March 2008 |
1NI7
|
86.4% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP01042
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2973 |
16766278 |
fucO |
L-1,2-propanediol oxidoreductase |
382 |
Phase 2: March 2008 |
1RRM
|
91.1% |
Salmonella enterica |
Energy metabolism |
Fermentation |
|
|
|
IDP01041
(show subtarget assignments)
|
1 |
purified |
No |
STM2971 |
16766276 |
sdaB |
L-serine dehydratase/L-threonine deamina... |
455 |
Phase 2: March 2008 |
2IQQ
|
16% |
Salmonella enterica |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP00549
(show subtarget assignments)
|
1 |
purified |
No |
YPO3814 |
16123948 |
ftsY |
cell division protein |
541 |
Phase 2: March 2008 |
2YHS
|
63.7% |
Yersinia pestis |
Cellular processes |
Cell division |
|
|
|
IDP01040
(show subtarget assignments)
|
1 |
expressed |
No |
STM2935 |
16766241 |
cysD |
sulfate adenylyltransferase subunit 2 |
302 |
Phase 2: March 2008 |
1ZUN
|
75.2% |
Salmonella enterica |
Central intermediary metabolism |
Sulfur metabolism |
|
|
|
IDP01039
(show subtarget assignments)
|
1 |
expressed |
No |
STM2934 |
16766240 |
cysN |
sulfate adenylyltransferase subunit 1 |
479 |
Phase 2: March 2008 |
1ZUN
|
52.4% |
Salmonella enterica |
Central intermediary metabolism |
Sulfur metabolism |
|
|
|
IDP00547
(show subtarget assignments)
|
1 |
expressed |
No |
YPO3813 |
16123947 |
ftsE |
cell division protein FtsE |
222 |
Phase 2: March 2008 |
3DHW
|
39.6% |
Yersinia pestis |
Cellular processes |
Cell division |
|
|
|
IDP01037
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM2927 |
16766233 |
surE |
stationary phase survival protein SurE |
253 |
Phase 2: March 2008 |
2V4N
|
100% |
Salmonella enterica |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP01036
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2897 |
16766203 |
invE |
invasion protein |
372 |
Phase 2: March 2008 |
2VJ5
|
26.1% |
Salmonella enterica |
Cellular processes |
Pathogenesis |
|
|
|
IDP01035
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM4146 |
16767400 |
tuf |
elongation factor Tu |
394 |
Phase 2: March 2008 |
1D8T
|
99.5% |
Salmonella enterica |
Protein synthesis |
Translation factors |
|
|
|
IDP01034
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM4089 |
16767355 |
menG |
ribonuclease activity regulator protein ... |
161 |
Phase 2: March 2008 |
1Q5X
|
97.5% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP01033
(show subtarget assignments)
|
1 |
soluble |
No |
STM3815 |
16767100 |
ccmE |
cytochrome c-type biogenesis protein Ccm... |
159 |
Phase 2: March 2008 |
1SR3
|
68.6% |
Salmonella enterica |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00545
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2747 |
16122951 |
fadJ |
multifunctional fatty acid oxidation com... |
774 |
Phase 2: March 2008 |
1WDK
|
34.1% |
Yersinia pestis |
Cellular processes |
Detoxification |
|
|
|
IDP01032
(show subtarget assignments)
|
1 |
soluble |
No |
STM3507 |
16766795 |
yhgG |
putative cytoplasmic protein |
78 |
Phase 2: March 2008 |
1XN7
|
89.7% |
Salmonella enterica |
Protein synthesis |
tRNA aminoacylation |
|
|
|
IDP01031
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM3497 |
16766785 |
yrfH |
ribosome-associated heat shock protein H... |
133 |
Phase 2: March 2008 |
1DM9
|
95.5% |
Salmonella enterica |
Protein synthesis |
Other |
|
|
|
IDP01030
(show subtarget assignments)
|
1 |
cloned |
No |
STM2107 |
16765437 |
wcaH |
GDP-mannose mannosyl hydrolase |
167 |
Phase 2: March 2008 |
2I8T
|
65.9% |
Salmonella enterica |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP01029
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM1916 |
16765258 |
cheY |
chemotaxis regulator transmitting signal... |
129 |
Phase 2: March 2008 |
2FKA
|
100% |
Salmonella enterica |
Cellular processes |
Other |
|
|
|
IDP00543
(show subtarget assignments)
|
1 |
purified |
No |
YPO4057 |
16124173 |
fdoH |
formate dehydrogenase-O, iron-sulfur sub... |
323 |
Phase 2: March 2008 |
1KQF
|
70.9% |
Yersinia pestis |
Energy metabolism |
Anaerobic |
|
|
|
IDP01027
(show subtarget assignments)
|
1 |
in_pdb |
No |
STM1346 |
16764697 |
ydiE |
hypothetical protein STM1346 |
63 |
Phase 2: March 2008 |
2LOJ
|
100% |
Salmonella enterica |
Protein synthesis |
tRNA aminoacylation |
|
|
|
IDP01026
(show subtarget assignments)
|
1 |
cloned |
No |
STM1267 |
16764618 |
|
putative cytoplasmic protein |
82 |
Phase 2: March 2008 |
2OXL
|
32.9% |
Salmonella enterica |
Protein synthesis |
tRNA aminoacylation |
|
|
|
IDP01025
(show subtarget assignments)
|
1 |
cloned |
No |
STM1196 |
16764551 |
acpP |
acyl carrier protein |
78 |
Phase 2: March 2008 |
1L0H
|
100% |
Salmonella enterica |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP00541
(show subtarget assignments)
|
1 |
purified |
No |
YPO1597 |
16121865 |
fabH |
3-oxoacyl-(acyl carrier protein) synthas... |
316 |
Phase 2: March 2008 |
1HN9
|
81.1% |
Yersinia pestis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP01024
(show subtarget assignments)
|
1 |
purified |
No |
STM1172 |
16764528 |
flgM |
anti-sigma28 factor FlgM |
97 |
Phase 2: March 2008 |
|
|
Salmonella enterica |
Cell envelope |
Surface structures |
|
|
|
IDP00540
(show subtarget assignments)
|
1 |
purified |
No |
YPO2719 |
16122923 |
era |
GTP-binding protein Era |
303 |
Phase 2: March 2008 |
1EGA
|
83.8% |
Yersinia pestis |
Cellular processes |
Cell division |
|
|
|
IDP01022
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM0048 |
16763438 |
slpA |
FKBP-type peptidyl-prolyl cis-trans isom... |
149 |
Phase 2: March 2008 |
3PR9
|
29.5% |
Salmonella enterica |
Protein synthesis |
Translation factors |
|
|
|
IDP01021
(show subtarget assignments)
|
1 |
cloned |
No |
STM0044 |
16763434 |
yaaY |
putative cytoplasmic protein |
71 |
Phase 2: March 2008 |
|
|
Salmonella enterica |
Protein synthesis |
tRNA aminoacylation |
|
|
|
IDP00539
(show subtarget assignments)
|
1 |
purified |
No |
YPO2751 |
16122955 |
aroC |
chorismate synthase |
361 |
Phase 2: March 2008 |
1R52
|
45% |
Yersinia pestis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01018
(show subtarget assignments)
|
1 |
expressed |
No |
STM2894 |
16766200 |
invC |
ATP synthase SpaL |
431 |
Phase 2: March 2008 |
2OBL
|
38.7% |
Salmonella enterica |
Transport and binding proteins |
Other |
|
|
|
IDP01017
(show subtarget assignments)
|
1 |
expressed |
No |
STM2854 |
16766160 |
hypA |
hydrogenase nickel incorporation protein... |
118 |
Phase 2: March 2008 |
3A43
|
24.6% |
Salmonella enterica |
Protein fate |
Protein modification and repair |
|
|
|
IDP00537
(show subtarget assignments)
|
1 |
purified |
No |
YPO3924 |
16124055 |
argH |
argininosuccinate lyase |
457 |
Phase 2: March 2008 |
1TJ7
|
88.8% |
Yersinia pestis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP01016
(show subtarget assignments)
|
1 |
cloned |
No |
STM2792 |
16766103 |
gabT |
4-aminobutyrate aminotransferase |
427 |
Phase 2: March 2008 |
1SF2
|
88.3% |
Salmonella enterica |
Central intermediary metabolism |
Other |
|
|
|
IDP01015
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM2791 |
16766102 |
gabD |
succinate-semialdehyde dehydrogenase I |
482 |
Phase 2: March 2008 |
3JZ4
|
90% |
Salmonella enterica |
Central intermediary metabolism |
Other |
|
|
|
IDP01013
(show subtarget assignments)
|
1 |
purified |
No |
STM2670 |
16765985 |
aroF |
phospho-2-dehydro-3-deoxyheptonate aldol... |
356 |
Phase 2: March 2008 |
1GG1
|
51.4% |
Salmonella enterica |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP01012
(show subtarget assignments)
|
1 |
purified |
No |
STM2578 |
16765898 |
pdxJ |
pyridoxal phosphate biosynthetic protein... |
243 |
Phase 2: March 2008 |
1M5W
|
93.8% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridoxine |
|
|
|
IDP01011
(show subtarget assignments)
|
1 |
in_pdb 3GBX |
Yes |
STM2555 |
16765875 |
glyA |
serine hydroxymethyltransferase |
417 |
Phase 2: March 2008 |
3GBX
|
100% |
Salmonella enterica |
Amino acid biosynthesis |
Serine family |
|
|
|
IDP00534
(show subtarget assignments)
|
1 |
purified |
No |
YPO3367 |
16123517 |
cysG |
siroheme synthase |
472 |
Phase 2: March 2008 |
1PJQ
|
52.5% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP01010
(show subtarget assignments)
|
1 |
purified |
No |
STM2539 |
16765859 |
hscA |
chaperone protein HscA |
616 |
Phase 2: March 2008 |
2KHO
|
40.9% |
Salmonella enterica |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP01009
(show subtarget assignments)
|
1 |
cloned |
No |
STM2535 |
16765855 |
sseB |
enhanced serine sensitivity protein |
261 |
Phase 2: March 2008 |
|
|
Salmonella enterica |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP00533
(show subtarget assignments)
|
1 |
purified |
No |
YPO0158 |
16120501 |
cysG |
siroheme synthase |
470 |
Phase 2: March 2008 |
1PJQ
|
70.2% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP01008
(show subtarget assignments)
|
1 |
soluble |
No |
STM2533 |
16765853 |
sseA |
3-mercaptopyruvate sulfurtransferase |
280 |
Phase 2: March 2008 |
1URH
|
79.6% |
Salmonella enterica |
Cellular processes |
Detoxification |
|
|
|
IDP01006
(show subtarget assignments)
|
1 |
soluble |
No |
STM2529 |
16765849 |
|
putative anaerobic dimethylsulfoxide red... |
209 |
Phase 2: March 2008 |
2VPW
|
31.6% |
Salmonella enterica |
Energy metabolism |
Anaerobic |
|
|
|
IDP01005
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2511 |
16765831 |
guaB |
inositol-5-monophosphate dehydrogenase |
488 |
Phase 2: March 2008 |
3TSB
|
55.9% |
Salmonella enterica |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP01004
(show subtarget assignments)
|
1 |
in_pdb 3G0S |
Yes |
STM2489 |
16765809 |
dapA |
dihydrodipicolinate synthase |
292 |
Phase 2: March 2008 |
3G0S
|
100% |
Salmonella enterica |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP01003
(show subtarget assignments)
|
1 |
cloned |
No |
STM2479 |
16765799 |
aegA |
putative oxidoreductase Fe-S binding sub... |
653 |
Phase 2: March 2008 |
2VDC
|
29.2% |
Salmonella enterica |
Central intermediary metabolism |
Other |
|
|
|
IDP01001
(show subtarget assignments)
|
1 |
soluble |
No |
STM2405 |
16765731 |
|
indolepyruvate decarboxylase |
550 |
Phase 2: March 2008 |
1OVM
|
66.7% |
Salmonella enterica |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP01000
(show subtarget assignments)
|
1 |
expressed |
No |
STM2389 |
16765716 |
fadI |
3-ketoacyl-CoA thiolase |
436 |
Phase 2: March 2008 |
1ULQ
|
35.8% |
Salmonella enterica |
Fatty acid and phospholipid metabolism |
Degradation |
|
|
|
IDP00999
(show subtarget assignments)
|
1 |
expressed |
No |
STM2388 |
16765715 |
fadJ |
multifunctional fatty acid oxidation com... |
715 |
Phase 2: March 2008 |
1WDK
|
35.8% |
Salmonella enterica |
Fatty acid and phospholipid metabolism |
Degradation |
|
|
|
IDP00998
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2369 |
16765696 |
usg |
hypothetical protein STM2369 |
337 |
Phase 2: March 2008 |
2QZ9
|
46.6% |
Salmonella enterica |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP00997
(show subtarget assignments)
|
1 |
soluble |
No |
STM2314 |
16765641 |
|
putative chemotaxis signal transduction ... |
333 |
Phase 2: March 2008 |
1K68
|
12% |
Salmonella enterica |
Cellular processes |
Chemotaxis and motility |
|
|
|
IDP00526
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO1351 |
16121631 |
artI |
arginine-binding periplasmic protein 1 p... |
243 |
Phase 2: March 2008 |
2Y7I
|
52.7% |
Yersinia pestis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00995
(show subtarget assignments)
|
1 |
in_pdb 3H02 |
No |
STM2307 |
16765634 |
menB |
naphthoate synthase |
285 |
Phase 2: March 2008 |
3H02
|
100% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP00994
(show subtarget assignments)
|
1 |
in_pdb 3GC2 |
No |
STM2306 |
16765633 |
menC |
O-succinylbenzoate synthase |
320 |
Phase 2: March 2008 |
3GC2
|
100% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP00993
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM2250 |
16765578 |
ccmE |
cytochrome c-type biogenesis protein Ccm... |
159 |
Phase 2: March 2008 |
1SR3
|
68.6% |
Salmonella enterica |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00992
(show subtarget assignments)
|
1 |
soluble |
No |
STM2227 |
16765556 |
yejL |
putative cytoplasmic protein |
75 |
Phase 2: March 2008 |
2JRX
|
90.7% |
Salmonella enterica |
Protein synthesis |
tRNA aminoacylation |
|
|
|
IDP00991
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2212 |
16765541 |
yeiR |
putative cobalamin biosynthetic protein ... |
328 |
Phase 2: March 2008 |
1NIJ
|
18.9% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP00524
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO0490 |
16120820 |
apaH |
diadenosine tetraphosphatase |
289 |
Phase 2: March 2008 |
2DFJ
|
73.7% |
Yersinia pestis |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP00990
(show subtarget assignments)
|
0 |
work_stopped |
No |
STM2193 |
16765523 |
folE |
GTP cyclohydrolase I |
222 |
Phase 2: March 2008 |
1FBX
|
95.5% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Folic acid |
|
|
|
IDP00989
(show subtarget assignments)
|
1 |
purified |
No |
STM2183 |
16765513 |
cdd |
cytidine deaminase |
294 |
Phase 2: March 2008 |
1AF2
|
87.4% |
Salmonella enterica |
Purines, pyrimidines, nucleosides, and nucleotides |
Salvage of nucleosides and nucleotides |
|
|
|
IDP00523
(show subtarget assignments)
|
1 |
in_pdb 3OZH 3RJU |
Yes |
YPO1224 |
16121513 |
ampH |
beta-lactamase/D-alanine carboxypeptidas... |
388 |
Phase 2: March 2008 |
3OZH
|
89.7% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00988
(show subtarget assignments)
|
1 |
expressed |
No |
STM2163 |
16765493 |
yehX |
putative ABC-type proline/glycine betain... |
315 |
Phase 2: March 2008 |
1V43
|
32.4% |
Salmonella enterica |
Transport and binding proteins |
Other |
|
|
|
IDP00987
(show subtarget assignments)
|
1 |
soluble |
No |
STM2147 |
16765476 |
thiM |
hydroxyethylthiazole kinase |
265 |
Phase 2: March 2008 |
1C3Q
|
36.6% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Thiamine |
|
|
|
IDP00522
(show subtarget assignments)
|
1 |
soluble |
No |
YPO3423 |
16123572 |
ampD |
N-acetyl-anhydromuranmyl-L-alanine amida... |
183 |
Phase 2: March 2008 |
1J3G
|
62.3% |
Yersinia pestis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00521
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO3180 |
16123342 |
thiL |
thiamine monophosphate kinase |
329 |
Phase 2: March 2008 |
3MCQ
|
41.3% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Thiamine |
|
|
|
IDP00985
(show subtarget assignments)
|
1 |
soluble |
No |
STM2076 |
16765406 |
hisA |
1-(5-phosphoribosyl)-5-[(5-phosphoribosy... |
245 |
Phase 2: March 2008 |
2Y85
|
35.1% |
Salmonella enterica |
Amino acid biosynthesis |
Histidine family |
|
|
|
IDP00984
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
STM2073 |
16765403 |
hisC |
histidinol-phosphate aminotransferase |
359 |
Phase 2: March 2008 |
1FG3
|
88% |
Salmonella enterica |
Amino acid biosynthesis |
Histidine family |
|
|
|
IDP00983
(show subtarget assignments)
|
1 |
cloned |
No |
STM2064 |
16765394 |
phsB |
thiosulfate reductase electron transport... |
192 |
Phase 2: March 2008 |
2VPW
|
37% |
Salmonella enterica |
Energy metabolism |
Electron transport |
|
|
|
IDP00520
(show subtarget assignments)
|
1 |
in_pdb 3F6M 3FPI |
No |
YPO3360 |
16123510 |
ispF |
2-C-methyl-D-erythritol 2,4-cyclodiphosp... |
162 |
Phase 2: March 2008 |
3F6M
|
100% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP00519
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3446 |
16123594 |
argI |
ornithine carbamoyltransferase subunit I... |
335 |
Phase 2: March 2008 |
1AKM
|
79.1% |
Yersinia pestis |
Amino acid biosynthesis |
Glutamate family |
|
|
|