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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 14 of 60, showing 100 records out of 5973 total, starting on record 1301
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90664
(
show subtarget assignments
)
8
cloned
No
Cj0024
15791423
nrdA
ribonucleotide-diphosphate reductase sub...
789
Predicted Essential
Community Requests
3HNC
33.7%
Campylobacter jejuni
IDP90665
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC2618
15642613
argD
bifunctional N-succinyldiaminopimelate-a...
403
Predicted Essential
Community Requests
2PB0
58.1%
Vibrio cholerae
IDP90670
(
show subtarget assignments
)
8
soluble
No
Cj1202
15792526
metF
5,10-methylenetetrahydrofolate reductase...
282
Predicted Essential
Community Requests
1V93
34%
Campylobacter jejuni
IDP90669
(
show subtarget assignments
)
8
in_pdb
3PAJ
Yes
VC2422
15642419
quinolinate phosphoribosyltransferase [V...
296
Predicted Essential
Community Requests
3PAJ
100%
Vibrio cholerae
IDP90671
(
show subtarget assignments
)
8
in_pdb
3O6C
3O6D
Yes
Cj1238
15792562
pdxJ
pyridoxal phosphate biosynthetic protein...
257
Predicted Essential
Community Requests
3O6C
100%
Campylobacter jejuni
IDP90673
(
show subtarget assignments
)
8
expressed
No
VC1833
15641835
quinolinate synthetase [Vibrio cholerae ...
353
Predicted Essential
Community Requests
1WZU
30.6%
Vibrio cholerae
IDP90676
(
show subtarget assignments
)
8
expressed
No
Cj0533
15791894
sucC
succinyl-CoA synthase, beta subunit [Cam...
387
Predicted Essential
Community Requests
1CQI
45.5%
Campylobacter jejuni
IDP90677
(
show subtarget assignments
)
8
crystallized
No
Cj0702
15792051
purE
phosphoribosylaminoimidazole carboxylase...
164
Predicted Essential
Community Requests
3TRH
53.7%
Campylobacter jejuni
IDP90679
(
show subtarget assignments
)
8
cloned
No
Cj0506
15791868
alaS
alanyl-tRNA synthetase [Campylobacter je...
842
Predicted Essential
Community Requests
3HXU
28.5%
Campylobacter jejuni
IDP90680
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj1401c
15792719
tpiA
triosephosphate isomerase [Campylobacter...
223
Predicted Essential
Community Requests
2JGQ
48.2%
Campylobacter jejuni
IDP90687
(
show subtarget assignments
)
8
in_pdb
3QM3
No
Cj0597
15791957
fba
fructose-bisphosphate aldolase [Campylob...
354
Predicted Essential
Community Requests
3QM3
100%
Campylobacter jejuni
IDP90686
(
show subtarget assignments
)
8
crystallized
No
Cj0918c
15792247
prsA
ribose-phosphate pyrophosphokinase [Camp...
309
Predicted Essential
Community Requests
3DAH
57.1%
Campylobacter jejuni
IDP90689
(
show subtarget assignments
)
8
soluble
No
Cj0389
15791756
serS
seryl-tRNA synthetase [Campylobacter jej...
411
Predicted Essential
Community Requests
2DQ3
48.4%
Campylobacter jejuni
IDP90688
(
show subtarget assignments
)
8
crystallized
No
Cj1595
15792900
rpoA
DNA-directed RNA polymerase subunit alph...
337
Predicted Essential
Community Requests
3IYD
31.5%
Campylobacter jejuni
IDP90692
(
show subtarget assignments
)
8
purified
No
YPO1638
16121906
trmU
tRNA (5-methylaminomethyl-2-thiouridylat...
371
Predicted Essential
Community Requests
2DER
85.7%
Yersinia pestis
IDP90691
(
show subtarget assignments
)
8
soluble
No
VC2643
15642638
acetylglutamate kinase [Vibrio cholerae ...
262
Predicted Essential
Community Requests
3T7B
59.5%
Vibrio cholerae
IDP90693
(
show subtarget assignments
)
8
purified
No
Cj1599
15792904
hisB
imidazole glycerol-phosphate dehydratase...
352
Predicted Essential
Community Requests
1RHY
25.6%
Campylobacter jejuni
IDP90694
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0840c
15792178
fbp
fructose-1,6-bisphosphatase [Campylobact...
280
Predicted Essential
Community Requests
3IFA
34.9%
Campylobacter jejuni
IDP00167
(
show subtarget assignments
)
8
in_pdb
3FZY
Yes
VC1451
4455065
rtxA
RTX toxin RtxA
4545
Virulence
Community Requests
3EEB
4.6%
Vibrio cholerae
Cellular processes
Pathogenesis
IDP90698
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj1531
15792839
dapF
diaminopimelate epimerase [Campylobacter...
249
Predicted Essential
Community Requests
3EJX
30.2%
Campylobacter jejuni
IDP90700
(
show subtarget assignments
)
8
soluble
No
Cj0196c
15791583
purF
amidophosphoribosyltransferase [Campylob...
445
Predicted Essential
Community Requests
1AO0
46.3%
Campylobacter jejuni
IDP90701
(
show subtarget assignments
)
8
soluble
No
Cj0545
15791906
hemC
porphobilinogen deaminase [Campylobacter...
307
Predicted Essential
Community Requests
1AH5
47.9%
Campylobacter jejuni
IDP90704
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0269c
15791640
ilvE
branched-chain amino acid aminotransfera...
304
Predicted Essential
Community Requests
3U0G
55.6%
Campylobacter jejuni
IDP90705
(
show subtarget assignments
)
8
soluble
No
Cj1400c
15792718
fabI
enoyl-(acyl carrier protein) reductase [...
274
Predicted Essential
Community Requests
2PD3
67.2%
Campylobacter jejuni
IDP90707
(
show subtarget assignments
)
8
purified
No
Cj0233c
15791605
pyrE
orotate phosphoribosyltransferase [Campy...
202
Predicted Essential
Community Requests
2YZK
22.3%
Campylobacter jejuni
IDP90708
(
show subtarget assignments
)
8
cloned
No
Cj0955c
15792284
purL
phosphoribosylformylglycinamidine syntha...
728
Predicted Essential
Community Requests
3AC6
40.2%
Campylobacter jejuni
IDP90714
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO1379
16121659
serS
seryl-tRNA synthetase [Yersinia pestis C...
430
Predicted Essential
Community Requests
2DQ3
55.3%
Yersinia pestis
IDP90713
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0995c
15792322
hemB
delta-aminolevulinic acid dehydratase [C...
327
Predicted Essential
Community Requests
1B4E
51.1%
Campylobacter jejuni
IDP90715
(
show subtarget assignments
)
8
expressed
No
Cj0534
15791895
sucD
succinyl-CoA synthase, alpha subunit [Ca...
289
Predicted Essential
Community Requests
1JKJ
58.1%
Campylobacter jejuni
IDP90716
(
show subtarget assignments
)
8
soluble
No
Cj0576
15791936
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine...
321
Predicted Essential
Community Requests
2IU8
35.5%
Campylobacter jejuni
IDP90720
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0348
15791716
trpB
tryptophan synthase subunit beta [Campyl...
392
Predicted Essential
Community Requests
1V8Z
51.5%
Campylobacter jejuni
IDP90719
(
show subtarget assignments
)
8
soluble
No
Cj0503c
15791865
hemH
ferrochelatase [Campylobacter jejuni sub...
303
Predicted Essential
Community Requests
2PO7
31%
Campylobacter jejuni
IDP90721
(
show subtarget assignments
)
8
crystallized
No
YPO1610
16121878
aroE
shikimate 5-dehydrogenase [Yersinia pest...
292
Predicted Essential
Community Requests
1NPY
52.4%
Yersinia pestis
IDP90722
(
show subtarget assignments
)
8
in_pdb
3OUZ
3OUU
No
Cj1290c
15792613
accC
biotin carboxylase [Campylobacter jejuni...
443
Predicted Essential
Community Requests
3OUU
100%
Campylobacter jejuni
IDP00751
(
show subtarget assignments
)
8
purified
No
SACOL2117
57286333
fbaA
fructose-bisphosphate aldolase
286
Drug Target Function
Community Requests
3Q94
75.9%
Staphylococcus aureus
Energy metabolism
Glycolysis/gluconeogenesis
IDP90726
(
show subtarget assignments
)
8
purified
No
YPO1390
16121670
aroA
3-phosphoshikimate 1-carboxyvinyltransfe...
428
Predicted Essential
Community Requests
1G6S
80.1%
Yersinia pestis
IDP90729
(
show subtarget assignments
)
8
crystallized
No
Cj0572
15791932
ribA
bifunctional 3,4-dihydroxy-2-butanone 4-...
339
Predicted Essential
Community Requests
3MGZ
29.5%
Campylobacter jejuni
IDP90728
(
show subtarget assignments
)
8
cloned
No
YPO1412
16121692
asnC
asparaginyl-tRNA synthetase [Yersinia pe...
466
Predicted Essential
Community Requests
1X54
34.3%
Yersinia pestis
IDP90731
(
show subtarget assignments
)
8
soluble
No
YPO4101
16124209
rnpA
ribonuclease P [Yersinia pestis CO92]
119
Predicted Essential
Community Requests
2LJP
89.1%
Yersinia pestis
IDP90732
(
show subtarget assignments
)
8
soluble
No
Cj1023c
15792350
asd
aspartate-semialdehyde dehydrogenase [Ca...
343
Predicted Essential
Community Requests
2QZ9
45.8%
Campylobacter jejuni
IDP90734
(
show subtarget assignments
)
8
selected
No
VC0517
15640541
RNA polymerase sigma factor RpoD [Vibrio...
625
Predicted Essential
Community Requests
3IYD
78.1%
Vibrio cholerae
IDP90735
(
show subtarget assignments
)
8
in_pdb
3QN3
Yes
Cj1672c
15792976
eno
phosphopyruvate hydratase [Campylobacter...
414
Predicted Essential
Community Requests
3QN3
100%
Campylobacter jejuni
IDP90742
(
show subtarget assignments
)
8
crystallized
No
Cj0947c
15792276
hydrolase, carbon-nitrogen family [Campy...
290
Predicted Essential
Community Requests
3IVZ
34.1%
Campylobacter jejuni
IDP04627
(
show subtarget assignments
)
8
cloned
No
BAS5321
49188305
replicative DNA helicase [Bacillus anthr...
453
Proposed to be essential proteins
Community Requests
2VYE
75.3%
Bacillus anthracis
IDP90744
(
show subtarget assignments
)
8
expressed
No
Cj1059c
15792386
gatA
aspartyl/glutamyl-tRNA amidotransferase ...
453
Predicted Essential
Community Requests
3H0L
47.9%
Campylobacter jejuni
IDP90743
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO3513
16123659
ispB
octaprenyl diphosphate synthase [Yersini...
323
Predicted Essential
Community Requests
3MZV
44.9%
Yersinia pestis
IDP90747
(
show subtarget assignments
)
8
soluble
No
Cj0001
15791400
dnaA
chromosomal replication initiation prote...
440
Predicted Essential
Community Requests
2Z4R
34.3%
Campylobacter jejuni
IDP90746
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0582
15791942
lysC
aspartate kinase [Campylobacter jejuni s...
400
Predicted Essential
Community Requests
3AB4
48.9%
Campylobacter jejuni
IDP90748
(
show subtarget assignments
)
8
in_pdb
3R0S
Yes
Cj0274
15791645
lpxA
UDP-N-acetylglucosamine acyltransferase ...
263
Predicted Essential
Community Requests
3R0S
100%
Campylobacter jejuni
IDP90749
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj1641
15792946
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--...
427
Predicted Essential
Community Requests
2WTZ
34.4%
Campylobacter jejuni
IDP90754
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0498
15791862
trpC
indole-3-glycerol phosphate synthase [Ca...
258
Predicted Essential
Community Requests
3TSM
39%
Campylobacter jejuni
IDP90753
(
show subtarget assignments
)
8
crystallized
No
Cj0586
15791946
ligA
NAD-dependent DNA ligase LigA [Campyloba...
647
Predicted Essential
Community Requests
2OWO
40.7%
Campylobacter jejuni
IDP90755
(
show subtarget assignments
)
8
cloned
No
YPO3841
16123976
uvrD
DNA-dependent helicase II [Yersinia pest...
720
Predicted Essential
Community Requests
2IS1
83.3%
Yersinia pestis
IDP90756
(
show subtarget assignments
)
8
soluble
No
YPO2429
16122649
pheS
phenylalanyl-tRNA synthetase subunit alp...
327
Predicted Essential
Community Requests
3PCO
90.2%
Yersinia pestis
IDP90760
(
show subtarget assignments
)
8
expressed
No
Cj0686
15792035
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosph...
357
Predicted Essential
Community Requests
3NOY
47.1%
Campylobacter jejuni
IDP90759
(
show subtarget assignments
)
8
expressed
No
YPO0553
16120881
murD
UDP-N-acetylmuramoyl-L-alanyl-D-glutamat...
438
Predicted Essential
Community Requests
1E0D
80.6%
Yersinia pestis
IDP90761
(
show subtarget assignments
)
8
cloned
No
Cj1061c
15792388
ileS
isoleucyl-tRNA synthetase [Campylobacter...
917
Predicted Essential
Community Requests
1FFY
38.8%
Campylobacter jejuni
IDP90762
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC0968
15640984
cysteine synthase A [Vibrio cholerae O1 ...
322
Predicted Essential
Community Requests
1FCJ
79.2%
Vibrio cholerae
IDP90768
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0665c
15792020
argG
argininosuccinate synthase [Campylobacte...
406
Predicted Essential
Community Requests
1J1Z
57.9%
Campylobacter jejuni
IDP90767
(
show subtarget assignments
)
8
soluble
No
YPO2607
16122820
nadD
nicotinic acid mononucleotide adenylyltr...
220
Predicted Essential
Community Requests
1K4K
56.4%
Yersinia pestis
IDP90769
(
show subtarget assignments
)
8
purified
No
VC0971
15640987
ligA
NAD-dependent DNA ligase LigA [Vibrio ch...
669
Predicted Essential
Community Requests
2OWO
65.8%
Vibrio cholerae
IDP90770
(
show subtarget assignments
)
8
soluble
No
YPO2433
16122654
thrS
threonyl-tRNA synthetase [Yersinia pesti...
642
Predicted Essential
Community Requests
1QF6
88.3%
Yersinia pestis
IDP00770
(
show subtarget assignments
)
8
in_pdb
3R2I
No
SACOL0473
57285500
superantigen-like protein
232
Virulence Associated Factor
Community Requests
3R2I
100%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP90773
(
show subtarget assignments
)
8
selected
No
VC2108
15642108
erythronate-4-phosphate dehydrogenase [V...
387
Predicted Essential
Community Requests
3OET
48.3%
Vibrio cholerae
IDP90776
(
show subtarget assignments
)
8
purified
No
STM2365
16765692
folC
bifunctional folylpolyglutamate synthase...
422
Predicted Essential
Community Requests
1W78
86.7%
Salmonella enterica
IDP90775
(
show subtarget assignments
)
8
cloned
No
YPO0345
16120680
dipZ
thiol:disulfide interchange protein prec...
595
Predicted Essential
Community Requests
1UC7
12.8%
Yersinia pestis
IDP90780
(
show subtarget assignments
)
8
soluble
No
VC0215
15640245
bifunctional phosphopantothenoylcysteine...
399
Predicted Essential
Community Requests
1U7U
32.8%
Vibrio cholerae
IDP90779
(
show subtarget assignments
)
8
cloned
No
YPO3497
16123643
nusA
transcription elongation factor NusA [Ye...
495
Predicted Essential
Community Requests
1K0R
24.4%
Yersinia pestis
IDP90781
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj1058c
15792385
guaB
inositol-5-monophosphate dehydrogenase [...
485
Predicted Essential
Community Requests
3TSB
61.6%
Campylobacter jejuni
IDP90782
(
show subtarget assignments
)
8
soluble
No
Cj1008c
15792335
aroB
3-dehydroquinate synthase [Campylobacter...
351
Predicted Essential
Community Requests
3CLH
51%
Campylobacter jejuni
IDP90785
(
show subtarget assignments
)
8
in_pdb
3N2L
Yes
VC0211
15640241
pyrE
orotate phosphoribosyltransferase [Vibri...
214
Predicted Essential
Community Requests
3N2L
100%
Vibrio cholerae
IDP90786
(
show subtarget assignments
)
8
cloned
No
Cj1385
15792708
katA
catalase [Campylobacter jejuni subsp. je...
474
Predicted Essential
Community Requests
2ISA
57.8%
Campylobacter jejuni
IDP90788
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0512
15791874
purC
phosphoribosylaminoimidazole-succinocarb...
236
Predicted Essential
Community Requests
3NUA
50.8%
Campylobacter jejuni
IDP90789
(
show subtarget assignments
)
8
in_pdb
4E77
No
YPO3389
16123538
hemL
glutamate-1-semialdehyde aminotransferas...
426
Predicted Essential
Community Requests
4E77
100%
Yersinia pestis
IDP04222
(
show subtarget assignments
)
8
selected
No
CAC05827
12329096
spa33
Spa33, component of the Mxi-Spa secretio...
293
Shigella effector protein
Community Requests
Shigella flexneri
IDP04066
(
show subtarget assignments
)
8
selected
No
CAC05819
12329088
mxiE
MxiE, similarities to transcriptional ac...
210
Shigella effector protein
Community Requests
Shigella flexneri
IDP04559
(
show subtarget assignments
)
8
selected
No
CAC05871
12329140
ospE1
OspE1, secreted by the Mxi-Spa secretion...
88
Shigella effector protein
Community Requests
Shigella flexneri
IDP04415
(
show subtarget assignments
)
8
selected
No
CAC05837
12329106
icsA (virG)
IcsA (VirG), outermembrane protein expos...
1102
Shigella effector protein
Community Requests
3ML3
15.2%
Shigella flexneri
IDP90797
(
show subtarget assignments
)
8
in_pdb
3MUE
No
STM0181
16763571
panC
pantoate--beta-alanine ligase [Salmonell...
284
Predicted Essential
Community Requests
3MUE
100%
Salmonella enterica
IDP04075
(
show subtarget assignments
)
8
selected
No
CAC05807
12329076
icsB
IcsB, function unknown [Shigella flexner...
494
Shigella effector protein
Community Requests
Shigella flexneri
IDP91636
(
show subtarget assignments
)
8
cloned
No
NP_217464
15610085
acyl-CoA synthetase [Mycobacterium tuber...
705
virulence/pathogenesis /
Required for the synthesis of the phthiocerol dimycocerosates and related compou...
Community Requests
2V7B
23%
Mycobacterium tuberculosis
IDP04117
(
show subtarget assignments
)
8
selected
No
CAC05825
12329094
spa13
spa13, component of the Mxi-Spa secretio...
112
Shigella effector protein
Community Requests
Shigella flexneri
IDP04414
(
show subtarget assignments
)
8
selected
No
CAC05786
12329055
sepA
SepA, extracellular serine protease of t...
1364
Shigella effector protein
Community Requests
1WXR
34.9%
Shigella flexneri
IDP04225
(
show subtarget assignments
)
8
cloned
No
CAC05803
12329072
ipaB
IpaB, secreted by the Mxi-Spa secretion ...
580
Shigella effector protein
Community Requests
3U0C
34.3%
Shigella flexneri
IDP04224
(
show subtarget assignments
)
8
selected
No
CAC05802
12329071
ipaC
IpaC, secreted by the Mxi-Spa secretion ...
363
Shigella effector protein
Community Requests
Shigella flexneri
IDP04223
(
show subtarget assignments
)
8
selected
No
CAC05808
12329077
ipgD
IpgD, secreted by the Mxi-Spa machinery,...
538
Shigella effector protein
Community Requests
Shigella flexneri
IDP04306
(
show subtarget assignments
)
8
selected
No
CAC05809
12329078
ipgE
IpgE, cytoplasmic chaperone for IpgD [Sh...
120
Shigella effector protein
Community Requests
1K3S
27.5%
Shigella flexneri
IDP04381
(
show subtarget assignments
)
8
selected
No
CAC05791
12329060
unnamed protein product [Shigella flexne...
296
Shigella effector protein
Community Requests
3MKL
8.4%
Shigella flexneri
IDP04336
(
show subtarget assignments
)
8
in_crystallization_trials
No
CAC05790
12329059
ospC1
OspC1, secreted by the Mxi-Spa secretion...
470
Shigella effector protein
Community Requests
Shigella flexneri
IDP04326
(
show subtarget assignments
)
8
purified
No
CAC05800
12329069
ipaA
IpaA, secreted by the Mxi-Spa machinery,...
633
Shigella effector protein
Community Requests
2FM8
10.7%
Shigella flexneri
IDP04538
(
show subtarget assignments
)
8
in_crystallization_trials
No
CAC05770
12329039
ospB
OspB, protein secreted by the Mxi-Spa se...
288
Shigella effector protein
Community Requests
Shigella flexneri
IDP91638
(
show subtarget assignments
)
8
expressed
No
NP_216897
15609518
polyketide synthetase MBTD (polyketide s...
1004
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2HG4
15.5%
Mycobacterium tuberculosis
IDP04442
(
show subtarget assignments
)
8
soluble
No
YPO0494
115346303
b0053
survival protein SurA precursor (peptidy...
434
virulence/pathogenesis /
drug target; conserved gene; putative drug target function;
Community Requests
1M5Y
71%
Yersinia pestis
Protein fate
Protein folding and stabilization
IDP04558
(
show subtarget assignments
)
8
selected
No
CAC05811
12329080
mxiG
MxiG, component of the Mxi-Spa secretion...
371
Shigella effector protein
Community Requests
4A4Y
34%
Shigella flexneri
IDP04537
(
show subtarget assignments
)
8
selected
No
CAC05780
12329049
virF
VirF, member of the AraC family of trans...
262
Shigella effector protein
Community Requests
3GBG
26.3%
Shigella flexneri
IDP04534
(
show subtarget assignments
)
8
selected
No
CAC05815
12329084
mxiK
MxiK, putative component of the Mxi-Spa ...
175
Shigella effector protein
Community Requests
Shigella flexneri
IDP04536
(
show subtarget assignments
)
8
selected
No
CAC05826
12329095
spa32
Spa32, secreted by and component of the ...
292
Shigella effector protein
Community Requests
Shigella flexneri
IDP04535
(
show subtarget assignments
)
8
selected
No
CAC05816
12329085
mxiN
MxiN, putative component of the Mxi-Spa ...
231
Shigella effector protein
Community Requests
Shigella flexneri
IDP91640
(
show subtarget assignments
)
8
cloned
No
NP_216900
15609521
bifunctional salicyl-AMP ligase/salicyl-...
565
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
1MD9
42.1%
Mycobacterium tuberculosis
IDP91639
(
show subtarget assignments
)
8
cloned
No
NP_216896
15609517
peptide synthetase MBTE (peptide synthas...
1682
virulence/pathogenesis /
All of the mbt genes are involved in biosynthesis of the mycobactins, which are ...
Community Requests
2VSQ
17.7%
Mycobacterium tuberculosis
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