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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 14 of 60, showing 100 records out of 5973 total, starting on record 1301
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP05690
(
show subtarget assignments
)
1
cloned
No
lmo1666
16803706
-
peptidoglycan linked protein (LPXTG) [Li...
1711
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Protein fate: Degradation of proteins, peptides, and glycopeptides
IDP05691
(
show subtarget assignments
)
1
cloned
No
lmo1800
16803840
-
hypothetical protein lmo1800 [Listeria m...
298
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1YWF
25.8%
Listeria monocytogenes
Energy metabolism: Sugars
IDP05698
(
show subtarget assignments
)
1
cloned
No
lmo2186
16804225
-
hypothetical protein lmo2186 [Listeria m...
207
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2O6P
26.1%
Listeria monocytogenes
Unclassified: Role category not yet assigned
IDP05699
(
show subtarget assignments
)
1
cloned
No
lmo2396
16804434
-
hypothetical protein lmo2396 [Listeria m...
940
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1O6S
10.9%
Listeria monocytogenes
Transport and binding proteins: Amino acids, peptides and amines
IDP05703
(
show subtarget assignments
)
1
cloned
No
lmo2578
16804616
-
hypothetical protein lmo2578 [Listeria m...
283
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3DS8
67.1%
Listeria monocytogenes
Hypothetical proteins: Conserved
IDP05704
(
show subtarget assignments
)
1
cloned
No
lmo2639
16804677
-
hypothetical protein lmo2639 [Listeria m...
138
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2KPP
33.3%
Listeria monocytogenes
Hypothetical proteins: Conserved
IDP05705
(
show subtarget assignments
)
1
cloned
No
lmo2642
16804680
-
hypothetical protein lmo2642 [Listeria m...
443
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2XMO
99.8%
Listeria monocytogenes
IDP05710
(
show subtarget assignments
)
1
cloned
No
SACOL1673
57650500
alaS
alanyl-tRNA synthetase [Staphylococcus a...
876
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1RIQ
25.9%
Staphylococcus aureus
Protein synthesis: tRNA aminoacylation
IDP05713
(
show subtarget assignments
)
1
cloned
No
BA_0189
30253696
oligopeptide ABC transporter, oligopepti...
536
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1B05
31.2%
Bacillus anthracis
Transport and binding proteins: Amino acids, peptides and amines
IDP05717
(
show subtarget assignments
)
1
cloned
No
BA_1098
30254828
wall-associated domain protein [Bacillus...
178
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05728
(
show subtarget assignments
)
1
cloned
No
CD0251
126697822
fliI
flagellum-specific ATP synthase [Clostri...
439
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2DPY
45.6%
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05731
(
show subtarget assignments
)
1
cloned
No
CD1033
126698617
mnaA
UDP-N-acetylglucosamine 2-epimerase [Clo...
374
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1O6C
60.4%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP05732
(
show subtarget assignments
)
1
cloned
No
CD1205
126698801
ispA
geranyltranstransferase [Clostridium dif...
295
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2J1P
45.8%
Clostridium difficile
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
IDP05733
(
show subtarget assignments
)
1
cloned
No
CD1208
126698804
putative RNA methyltransferase [Clostrid...
270
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
3HP7
50.7%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05734
(
show subtarget assignments
)
1
cloned
No
CD1470
126699074
putative phage shock protein [Clostridiu...
99
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3GK5
33.3%
Clostridium difficile
Cellular processes: Adaptations to atypical conditions
IDP05738
(
show subtarget assignments
)
1
cloned
No
CD2090
126699707
putative xanthine/uracile permease [Clos...
453
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3QE7
28%
Clostridium difficile
Transport and binding proteins: Nucleosides, purines and pyrimidines
IDP05739
(
show subtarget assignments
)
1
cloned
No
CD2136
126699752
uppS
undecaprenyl pyrophosphate synthetase [C...
244
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1F75
52.9%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP05740
(
show subtarget assignments
)
1
cloned
No
CD2372
126699987
nadA
quinolinate synthetase [Clostridium diff...
304
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2QS0
42.1%
Clostridium difficile
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
IDP05742
(
show subtarget assignments
)
1
cloned
No
CD2655
126700269
murF
UDP-N-acetylmuramoyl-tripeptide--D-alany...
457
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1GG4
31.2%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP05743
(
show subtarget assignments
)
1
cloned
No
CD2653
126700267
murD
UDP-N-acetylmuramoylalanine--D-glutamate...
451
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3LK7
38.9%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP05744
(
show subtarget assignments
)
1
cloned
No
CD2744
126700359
relA
putative GTP pyrophosphokinase [Clostrid...
735
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1VJ7
26.4%
Clostridium difficile
Cellular processes: Adaptations to atypical conditions
IDP05746
(
show subtarget assignments
)
1
cloned
No
CD3402
126701025
murB
UDP-N-acetylenolpyruvoylglucosamine redu...
317
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3TX1
43.1%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP05747
(
show subtarget assignments
)
1
cloned
No
CD3439
126701062
cobT
nicotinate-nucleotide--dimethylbenzimida...
348
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1D0S
43.4%
Clostridium difficile
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
IDP05748
(
show subtarget assignments
)
1
cloned
No
Cj0435
6967908
fabG
phosphoglycerate mutase [Campylobacter j...
247
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2P68
48.8%
Campylobacter jejuni
Fatty acid and phospholipid metabolism: Biosynthesis
IDP05749
(
show subtarget assignments
)
1
cloned
No
Cj0775c
6968216
valS
putative periplasmic protein [Campylobac...
870
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1GAX
38.2%
Campylobacter jejuni
Protein synthesis: tRNA aminoacylation
IDP05750
(
show subtarget assignments
)
1
cloned
No
lmo0237
16802283
gltX
hypothetical protein lmo0237 [Listeria m...
491
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2O5R
43.2%
Listeria monocytogenes
Protein synthesis: tRNA aminoacylation
IDP05753
(
show subtarget assignments
)
1
cloned
No
lmo0461
16802505
-
hypothetical protein lmo0461 [Listeria m...
157
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05754
(
show subtarget assignments
)
1
cloned
No
lmo0627
16802669
-
pepdidoglycan bound protein [Listeria mo...
1582
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1D2P
8.4%
Listeria monocytogenes
Energy metabolism: Electron transport
IDP05756
(
show subtarget assignments
)
1
cloned
No
lmo0814
16802856
-
hypothetical protein lmo0814 [Listeria m...
309
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
3BO9
50.2%
Listeria monocytogenes
Unclassified: Role category not yet assigned
IDP05757
(
show subtarget assignments
)
1
cloned
No
lmo0881
16802922
-
hypothetical protein lmo0881 [Listeria m...
159
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05758
(
show subtarget assignments
)
1
cloned
No
lmo1552
16803592
valS
valyl-tRNA synthetase [Listeria monocyto...
883
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1GAX
40%
Listeria monocytogenes
Protein synthesis: tRNA aminoacylation
IDP05759
(
show subtarget assignments
)
1
cloned
No
lmo1759
16803799
pcrA
ATP-dependent DNA helicase [Listeria mon...
733
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1PJR
65.1%
Listeria monocytogenes
DNA metabolism: DNA replication, recombination, and repair
IDP05761
(
show subtarget assignments
)
1
cloned
No
lmo2125
16804164
-
hypothetical protein lmo2125 [Listeria m...
419
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2XD2
49.6%
Listeria monocytogenes
Unclassified: Role category not yet assigned
IDP05763
(
show subtarget assignments
)
1
cloned
No
lmo2331
16804370
-
hypothetical protein lmo2331 [Listeria m...
226
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05768
(
show subtarget assignments
)
1
cloned
No
SACOL0553
57651385
hypothetical protein SACOL0553 [Staphylo...
431
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
3A2K
28.1%
Staphylococcus aureus
Protein synthesis: tRNA and rRNA base modification
IDP05769
(
show subtarget assignments
)
1
cloned
No
SACOL0574
57651404
gltX
glutamyl-tRNA synthetase [Staphylococcus...
484
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2O5R
43.2%
Staphylococcus aureus
Protein synthesis: tRNA aminoacylation
IDP05770
(
show subtarget assignments
)
1
cloned
No
VC_0465
9654891
tyrosyl-tRNA synthetase [Vibrio cholerae...
434
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2TS1
50%
Vibrio cholerae
Protein synthesis: tRNA aminoacylation
IDP05771
(
show subtarget assignments
)
1
cloned
No
Z0339
12513053
alpha replication protein of prophage CP...
777
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1KA8
9.5%
Escherichia coli
Mobile and extrachromosomal element functions: Prophage functions
IDP05772
(
show subtarget assignments
)
1
cloned
No
Z3171
12516188
dacD
penicillin binding protein 6b [Escherich...
425
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1NZO
40.7%
Escherichia coli
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP90000
(
show subtarget assignments
)
8
cloned
No
FTT1352
56708408
hypothetical protein FTT1352
383
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Francisella tularensis
IDP90001
(
show subtarget assignments
)
8
cloned
No
FTT0094c
56603762
qseC
sensor histidine kinase
475
Drug Target (Community Request)
Community Requests
3A0R
15.8%
Francisella tularensis
IDP90007
(
show subtarget assignments
)
8
cloned
No
Z4378
12517596
qseC
quorum sensing Escherichia coli regulato...
449
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3JZ3
47%
Escherichia coli
IDP90081
(
show subtarget assignments
)
8
cloned
No
ABD79034.1
89892477
M2
matrix protein 2 [Influenza A virus (A/U...
96
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2L0J
42.7%
Influenza A
IDP90083
(
show subtarget assignments
)
8
cloned
No
ZP_01795671
145640077
hypothetical protein CGSHiII_00664 [Haem...
219
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
35.6%
Haemophilus influenzae
IDP90087
(
show subtarget assignments
)
8
cloned
No
ZZZ_0003
168
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90094
(
show subtarget assignments
)
8
cloned
No
ZZZ_0010
358
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90097
(
show subtarget assignments
)
8
cloned
No
ZZZ_0013
104
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90099
(
show subtarget assignments
)
8
cloned
No
ZZZ_0015
1137
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90103
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_003
68449080
ankyrin-like protein [Monkeypox virus]
587
similar to VACV-COP-B25R/C19L, MPXV-ZAI96-J3L/J1R
Community Requests
Monkeypox virus
IDP90106
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_011
68449085
secreted epidermal growth factor-like pr...
142
similar to VACV-COP-C11R, MPXV-ZAI96-D3R
Community Requests
1K36
16.2%
Monkeypox virus
IDP90109
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_014
68449088
interleukin-18-binding protein [Monkeypo...
126
similar to VACWR-C12L,VARV-BSH75_banu-D7L, MPXV-ZAI96-D6L
Community Requests
3F62
79.4%
Monkeypox virus
IDP90116
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_025
68449099
kelch-like protein [Monkeypox virus]
107
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
3HVE
21.5%
Monkeypox virus
IDP90120
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_030
68449104
unknown [Monkeypox virus]
220
similar to VACV-COP-M2L, MPXV-ZAI96-O2L
Community Requests
Monkeypox virus
IDP90124
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_036
68449110
unknown [Monkeypox virus]
219
mitochondrial-associated inhibitor of apoptosis, similar to VACV-COP-F1L, MPXV-Z...
Community Requests
2VTY
69.4%
Monkeypox virus
IDP90129
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_084
68449158
myristylprotein [Monkeypox virus]
340
similar to VACV-COP-G9R, MPXV-ZAI96-G10R
Community Requests
Monkeypox virus
IDP90130
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_133
68449207
soluble myristylprotein [Monkeypox virus...
377
similar to VACV-COP-A16L, MPXV-ZAI96-A17L
Community Requests
Monkeypox virus
IDP90131
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_144
68449218
cowpox A-type inclusion protein [Monkeyp...
67
similar to part of CPXV-GRI-A26L
Community Requests
Monkeypox virus
IDP90133
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_159
68449233
CD47-like putative membrane protein [Mon...
277
similar to VACV-COP-A38L, MPXV-ZAI96-A40L
Community Requests
2JJS
11.6%
Monkeypox virus
IDP90137
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_179
68449250
ankyrin-like protein [Monkeypox virus]
561
similar to VACV-COP-B4R, MPXV-ZAI96-B5R
Community Requests
1N11
11.2%
Monkeypox virus
IDP90138
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_181
68449252
ankyrin-like protein [Monkeypox virus]
119
similar to VACV-COP-B6R, MPXV-ZAI96-B7R
Community Requests
Monkeypox virus
IDP90139
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_182
68449253
bifunctional 21kDa precursor protein of ...
182
virulence, ER resident, similar to VACV-COP-B7R, N-terminal signal peptide, bifu...
Community Requests
Monkeypox virus
IDP90143
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_189
68449260
bifunctional IL-1-beta-inhibitor/prevent...
210
contains IG fold, similar to VACV-WR-197, MPXV-ZAR_1979_005-184
Community Requests
3O4O
29.5%
Monkeypox virus
IDP90145
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_192
68449264
IFN-alpha/beta-receptor-like secreted gl...
352
similar to VACV-COP-B19R, MPXV-ZAI96-B16R
Community Requests
3OQ3
83.2%
Monkeypox virus
IDP90147
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_194
68449266
kelch-like protein [Monkeypox virus]
70
similar to CPXV-GRI-B19R, MPXV-ZAI96-B18R
Community Requests
2Q81
31.4%
Monkeypox virus
IDP90150
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_202
68449275
unknown [Monkeypox virus]
176
similar to CPXV-GRI-C2L, MPXV-ZAI96-N3R
Community Requests
Monkeypox virus
IDP90171
(
show subtarget assignments
)
8
cloned
No
AAM13460.1
20152999
CPXV013 CDS
CPXV013 protein
523
kelch-like protein
Community Requests
3HVE
10.1%
Cowpox virus
conserved hypothetical proteins
0
IDP90172
(
show subtarget assignments
)
8
cloned
No
AAM13463.1
20153002
CPXV016 CDS
CPXV016 protein
764
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90173
(
show subtarget assignments
)
8
cloned
No
AAM13464.1
20153003
CPXV017 CDS
CPXV017 protein
435
ankyrin repeat protein
Community Requests
2BKG
9.9%
Cowpox virus
conserved hypothetical proteins
0
IDP90174
(
show subtarget assignments
)
8
cloned
No
AAM13466.1
20153005
CPXV019 CDS
CPXV019 protein
796
ankyrin repeat protein
Community Requests
3HG0
3.8%
Cowpox virus
conserved hypothetical proteins
0
IDP90179
(
show subtarget assignments
)
8
cloned
No
AAM13473.1
20153012
CPXV025 CDS
CPXV026 protein
63
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90180
(
show subtarget assignments
)
8
cloned
No
AAM13474.1
20153013
CPXV027 CDS
CPXV027 protein
632
ankyrin-like protein
Community Requests
3NOC
5.4%
Cowpox virus
conserved hypothetical proteins
0
IDP90181
(
show subtarget assignments
)
8
cloned
No
AAM13478.1
20153017
CPXV031 CDS
CPXV031 protein
69
kelch-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90183
(
show subtarget assignments
)
8
cloned
No
AAM13482.1
20153021
CPXV035 CDS
CPXV035 protein
512
kelch-like protein
Community Requests
2XN4
12.7%
Cowpox virus
conserved hypothetical proteins
0
IDP90186
(
show subtarget assignments
)
8
cloned
No
AAM13489.1
20153028
SPI3
SPI3 or CPXV042 protein
373
serine protease inhibitor 3
Community Requests
3LW2
28.7%
Cowpox virus
host defense modulator
0
IDP90187
(
show subtarget assignments
)
8
cloned
No
AAM13490.1
20153029
CPXV043 CDS
CPXV043 protein
88
IFN resistance, K3L like
Community Requests
1LUZ
90.9%
Cowpox virus
host defense modulator
0
IDP90188
(
show subtarget assignments
)
8
cloned
No
AAM13496.1
20153035
CPXV050 CDS
CPXV050 protein
480
kelch-like protein
Community Requests
3II7
12.3%
Cowpox virus
conserved hypothetical proteins
0
IDP90189
(
show subtarget assignments
)
8
cloned
No
AAM13616.1
20153155
CPXV175 CDS
CPXV175 protein
277
CD47-like putative membrane protein
Community Requests
2JJS
13%
Cowpox virus
host defense modulator
0
IDP90190
(
show subtarget assignments
)
8
cloned
No
AAM13631.1
20153170
CrmC
CrmC or CPXV191 protein
186
soluble vTNF receptor CrmC
Community Requests
3ALQ
30.6%
Cowpox virus
host defense modulator
0
IDP90192
(
show subtarget assignments
)
8
cloned
No
AAM13635.1
20153174
CPXV196 CDS
CPXV196 protein
299
serine-threonine kinase
Community Requests
2KTY
40.7%
Cowpox virus
Unknown function
0
IDP90193
(
show subtarget assignments
)
8
cloned
No
AAM13637.1
20153176
CPXV198 CDS
CPXV198 protein
558
ankyrin-like protein
Community Requests
1N11
11.1%
Cowpox virus
conserved hypothetical proteins
0
IDP90196
(
show subtarget assignments
)
8
cloned
No
AAM13643.1
20153182
CPXV204 CDS
CPXV204 protein
501
kelch-like protein
Community Requests
2VPJ
14%
Cowpox virus
conserved hypothetical proteins
0
IDP90199
(
show subtarget assignments
)
8
cloned
No
AAM13650.1
20153189
CPXV211 CDS
CPXV211 protein
574
ankyrin-like protein
Community Requests
3F6Q
5.6%
Cowpox virus
conserved hypothetical proteins
0
IDP90201
(
show subtarget assignments
)
8
cloned
No
AAM13653.1
20153192
CPXV215 CDS
CPXV215 Protein
557
kelch-like protein
Community Requests
2VPJ
12.2%
Cowpox virus
conserved hypothetical proteins
0
IDP90202
(
show subtarget assignments
)
8
cloned
No
AAM13655.1
20153194
CPXV217 CDS
CPXV217 protein
372
serine-protease inhibitor (SPI-1)
Community Requests
1F0C
40.9%
Cowpox virus
host defense modulator
0
IDP90204
(
show subtarget assignments
)
8
cloned
No
AAM13452.1
20152991
CPXV006 CDS
CPXV006 protein
619
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90211
(
show subtarget assignments
)
8
cloned
No
MYXV_gp132
9633764
m128L
m128L
281
integrin-associated protein homolog similar to VACV-Cop:A38L. Five pass TM prote...
Community Requests
Myxoma virus
host defense modulator
0
IDP90212
(
show subtarget assignments
)
8
cloned
No
MYXV_gp067
9633699
m063R
m063R, m63R
215
CD47-like
Community Requests
Myxoma virus
host range factor, host defense modulator
0
IDP90221
(
show subtarget assignments
)
8
cloned
No
MYXV_gp157
9633790
m154L
m154L, gp120-like
214
NFkB inhibitor, similar to VACV-Cop:M2L
Community Requests
Myxoma virus
host defense modulator
0
IDP90272
(
show subtarget assignments
)
8
cloned
No
TGME49_111670
211962063
hypothetical protein TGME49_111670 [Toxo...
440
Unpublished data from signature-tagged mutagenesis (STM) has identified this sur...
Community Requests
Toxoplasma gondii
IDP90273
(
show subtarget assignments
)
8
cloned
No
TGME49_013900
211968791
regulator of chromosome condensation, pu...
1155
Signature-tagged mutagenesis (STM) has identified the regulator of chromosome co...
Community Requests
3MVD
11.1%
Toxoplasma gondii
IDP90276
(
show subtarget assignments
)
8
cloned
No
TGME49_032600
211965793
patatin-like phospholipase domain-contai...
664
Signature-tagged mutagenesis (STM) has identified this patatin-like phospholipas...
Community Requests
Toxoplasma gondii
IDP90283
(
show subtarget assignments
)
8
cloned
No
TGME49_075440
211969603
GRA6
granule antigen protein GRA6 [Toxoplasma...
224
GRA6 is a secreted dense granule protein that generates protective immunity, e.g...
Community Requests
Toxoplasma gondii
IDP90292
(
show subtarget assignments
)
8
cloned
No
TGGT1_004130
221483205
histone acetyltransferase GCN5, putative...
1169
The histone acetyltransferase TgGCN-5A acetylates prerentially Histone 3 [K18], ...
Community Requests
1Z4R
8.5%
Toxoplasma gondii
IDP90295
(
show subtarget assignments
)
8
cloned
No
TGME49_005290
211965425
dual-specificity phosphatase laforin, pu...
523
Human Lafora disease is one of five major progressive myoclonus epilepsies that ...
Community Requests
Toxoplasma gondii
IDP90305
(
show subtarget assignments
)
8
cloned
No
CT_681
3329133
ompA
Major Outer Membrane Protein [Chlamydia ...
393
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90306
(
show subtarget assignments
)
8
cloned
No
CT_694
3329148
hypothetical protein [Chlamydia trachoma...
323
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90307
(
show subtarget assignments
)
8
cloned
No
CT_695
3329149
hypothetical protein [Chlamydia trachoma...
398
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90308
(
show subtarget assignments
)
8
cloned
No
CT_700
3329154
hypothetical protein [Chlamydia trachoma...
441
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1NA0
6.3%
Chlamydia trachomatis
IDP90309
(
show subtarget assignments
)
8
cloned
No
CT_702
3329157
hypothetical protein [Chlamydia trachoma...
175
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90311
(
show subtarget assignments
)
8
cloned
No
CT_734
3329192
hypothetical protein [Chlamydia trachoma...
221
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
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