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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 15 of 60, showing 100 records out of 5973 total, starting on record 1401
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP01747
(
show subtarget assignments
)
1
soluble
No
STM2407
16765733
ypeC
putative periplasmic protein [Salmonella...
108
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02695
(
show subtarget assignments
)
1
soluble
No
Cj0698
15792047
flgG
flagellar basal body rod protein FlgG [C...
263
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
3A69
23.6%
Campylobacter jejuni
Unknown function
Enzymes of unknown specificity
IDP00874
(
show subtarget assignments
)
1
cloned
No
STM1275
16764626
yaoF
putative hemolysin
83
Conserved Gene / Pathway
Phase 2: March 2008
Salmonella enterica
Unknown function
General
IDP04110
(
show subtarget assignments
)
1
expressed
No
YPO2440
218929529
yfeB
ATP-binding transport protein [Yersinia ...
296
virulence factor; conserved gene;
Phase 4: April 2009
3GFO
26.4%
Yersinia pestis
Unknown function
General
IDP00192
(
show subtarget assignments
)
1
cloned
No
YPO0947
16121251
-
putative virulence determinant
3110
Virulence
Phase 1: October 2007
1AF0
2.9%
Yersinia pestis
Unknown function
Enzymes of unknown specificity
IDP01810
(
show subtarget assignments
)
1
cloned
No
STM3187
16766487
ygiB
hypothetical protein STM3187 [Salmonella...
223
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP00191
(
show subtarget assignments
)
1
cloned
No
YPO0932
16121236
-
conserved hypothetical protein
170
Virulence
Phase 1: October 2007
Yersinia pestis
Unknown function
Enzymes of unknown specificity
IDP90192
(
show subtarget assignments
)
8
cloned
No
AAM13635.1
20153174
CPXV196 CDS
CPXV196 protein
299
serine-threonine kinase
Community Requests
2KTY
40.7%
Cowpox virus
Unknown function
0
IDP01903
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM0750
16764120
ybgF
hypothetical protein STM0750 [Salmonella...
262
Conserved; Drug target functions
Phase 3: June 2008
2WZ7
25.6%
Salmonella enterica
Unknown function
General
IDP00452
(
show subtarget assignments
)
1
purified
No
YPO2245
16122473
electron transport complex protein RnfB ...
188
Conserved Gene / Pathway
Phase 2: March 2008
1GT8
14.4%
Yersinia pestis
Unknown function
General
IDP01723
(
show subtarget assignments
)
1
in_pdb
3KAX
No
GBAA5138
47530443
aminotransferase, classes I and II [Baci...
383
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
3KAX
100%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP01722
(
show subtarget assignments
)
1
soluble
No
STM1881
16765223
yebF
hypothetical protein STM1881 [Salmonella...
117
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP00844
(
show subtarget assignments
)
1
diffraction
No
SACOL0519
57285544
acetyltransferase, GNAT family
174
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP02675
(
show subtarget assignments
)
1
expressed
No
CBU_1842
29542398
GTP-binding protein YchF [Coxiella burne...
363
Conserved; Drug target functions
Phase 3: June 2008
1JAL
65.3%
Coxiella burnetii
Unknown function
General
IDP00093
(
show subtarget assignments
)
1
expressed
No
NT01SF0510
30040252
ybbF
hypothetical protein S0463
240
Essential
Phase 1: October 2007
Shigella flexneri
Unknown function
General
IDP00842
(
show subtarget assignments
)
1
purified
No
SACOL1186
57284471
antibacterial protein (phenol soluble mo...
44
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
Unknown function
General
IDP02658
(
show subtarget assignments
)
1
cloned
No
STM2648
16765968
yfiF
putative methyltransferase [Salmonella t...
345
Conserved; Essential; Drug target functions
Phase 3: June 2008
1X7O
20.6%
Salmonella enterica
Unknown function
General
IDP00840
(
show subtarget assignments
)
1
purified
No
SACOL1894
57284813
HIT family protein
140
Drug Target Function
Phase 2: March 2008
1Y23
52.1%
Staphylococcus aureus
Unknown function
General
IDP01706
(
show subtarget assignments
)
1
cloned
No
STM1438
16764786
ydhL
putative oxidoreductase [Salmonella typh...
79
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP04114
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO1611
115347358
conserved hypothetical protein [Yersinia...
117
drug target; conserved gene;
Phase 4: April 2009
3N1S
84.6%
Yersinia pestis
Unknown function
General
IDP01809
(
show subtarget assignments
)
1
purified
No
FTT0258
56707414
carboxylesterase/phospholipase family pr...
222
Drug Target
Phase 3: June 2008
1FJ2
39.6%
Francisella tularensis
Unknown function
Enzymes of unknown specificity
IDP02262
(
show subtarget assignments
)
1
purified
No
FTT1532
56708566
hypothetical protein FTT1532 [Francisell...
162
Drug Target
Phase 3: June 2008
3NWZ
16%
Francisella tularensis
Unknown function
General
IDP90197
(
show subtarget assignments
)
8
soluble
No
AAM13645.1
20153184
CPXV206 CDS
CPXV206 protein
285
serine-threonine kinase
Community Requests
2KTY
32.1%
Cowpox virus
Unknown function
0
IDP01700
(
show subtarget assignments
)
1
expressed
No
CBU_1899
29542456
methyltransferase, putative [Coxiella bu...
193
Conserved; Drug target functions
Phase 3: June 2008
2FPO
51%
Coxiella burnetii
Unknown function
Enzymes of unknown specificity
IDP00832
(
show subtarget assignments
)
1
in_pdb
3IB3
3III
No
SACOL2612
57286517
hydrolase, CocE/NonD family
560
Drug Target Function
Phase 2: March 2008
3IB3
100%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP01894
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM0564
16763941
pyridine nucleotide-disulfide oxidoreduc...
441
Conserved; Drug target functions
Phase 3: June 2008
2EQ6
32.7%
Salmonella enterica
Unknown function
Enzymes of unknown specificity
IDP02247
(
show subtarget assignments
)
1
expressed
No
FTT0665c
56707786
aldolase/adducin class II family protein...
201
Drug Target
Phase 3: June 2008
3OCR
32.3%
Francisella tularensis
Unknown function
General
IDP00443
(
show subtarget assignments
)
1
soluble
No
YPO0908
16121213
visC
hypothetical protein YPO0908
406
Drug Target Function
Phase 2: March 2008
2R0C
24.3%
Yersinia pestis
Unknown function
General
IDP01681
(
show subtarget assignments
)
1
cloned
No
GBAA4795
47530092
hypothetical protein GBAA4795 [Bacillus ...
572
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
3AU2
37.1%
Bacillus anthracis
Unknown function
General
IDP01678
(
show subtarget assignments
)
1
cloned
No
GBAA5591
47530913
cardiolipin synthetase domain-containing...
397
Drug target motif; Involved in sporulation;
Phase 3: June 2008
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP02237
(
show subtarget assignments
)
1
in_pdb
3T4X
No
GBAA3440
47528725
short chain dehydrogenase/reductase fami...
264
Conserved; Essential;
Phase 3: June 2008
3T4X
100%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP02656
(
show subtarget assignments
)
1
expressed
No
FTT0558
56707688
short chain dehydrogenase [Francisella t...
203
Drug Target
Phase 3: June 2008
3D7L
41.9%
Francisella tularensis
Unknown function
Enzymes of unknown specificity
IDP01672
(
show subtarget assignments
)
1
soluble
No
GBAA5133
47530438
hypothetical protein GBAA5133 [Bacillus ...
396
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
1DJU
48.2%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP01668
(
show subtarget assignments
)
1
soluble
No
GBAA0060
47525314
hypothetical protein GBAA0060 [Bacillus ...
160
Essential;
Phase 3: June 2008
2K4K
29.4%
Bacillus anthracis
Unknown function
General
IDP01659
(
show subtarget assignments
)
1
crystallized
No
CBU_1739
29542296
tetrapyrrole (Corrin/Porphyrin) methylas...
285
Conserved; Drug target functions
Phase 3: June 2008
3KWP
42.1%
Coxiella burnetii
Unknown function
General
IDP02230
(
show subtarget assignments
)
1
cloned
No
YPO0829
16121138
putative sulfatase [Yersinia pestis CO92...
517
Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...
Phase 3: June 2008
2QZU
40.2%
Yersinia pestis
Unknown function
Enzymes of unknown specificity
IDP01649
(
show subtarget assignments
)
1
expressed
No
CBU_0796
29541390
HIT family protein [Coxiella burnetii RS...
113
Conserved; Drug target functions
Phase 3: June 2008
1AV5
49.6%
Coxiella burnetii
Unknown function
General
IDP01769
(
show subtarget assignments
)
1
soluble
No
STM2532
16765852
putative inner membrane lipoprotein [Sal...
1644
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP00179
(
show subtarget assignments
)
1
cloned
No
YPO0277
16120616
-
putative transmembrane transport protein...
428
Similar to Essential SALTY
Phase 1: October 2007
Yersinia pestis
Unknown function
General
IDP01640
(
show subtarget assignments
)
1
in_crystallization_trials
No
GBAA4357
47529653
short chain dehydrogenase/reductase fami...
264
Conserved; Essential;
Phase 3: June 2008
3P19
33.7%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP01639
(
show subtarget assignments
)
1
cloned
No
GBAA4225
47529518
aminotransferase A [Bacillus anthracis s...
387
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
1GD9
39.5%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP02202
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT0774
56707886
hypothetical protein FTT0774 [Francisell...
125
Drug Target
Phase 3: June 2008
3USH
52.8%
Francisella tularensis
Unknown function
General
IDP01625
(
show subtarget assignments
)
1
expressed
No
FTT1761
56708756
hypothetical protein FTT1761 [Francisell...
239
Drug Target
Phase 3: June 2008
Francisella tularensis
Unknown function
Enzymes of unknown specificity
IDP02628
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM2923
16766229
putative cytoplasmic protein [Salmonella...
78
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01622
(
show subtarget assignments
)
1
cloned
No
STM4396
16767642
ytfB
putative cell envelope opacity-associate...
211
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01621
(
show subtarget assignments
)
1
cloned
No
STM1984
16765321
yodD
putative cytoplasmic protein [Salmonella...
75
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02199
(
show subtarget assignments
)
1
expressed
No
CBU_1505
29542064
lepA
GTP-binding protein LepA [Coxiella burne...
614
Conserved; Drug target functions
Phase 3: June 2008
3CB4
69.9%
Coxiella burnetii
Unknown function
General
IDP02609
(
show subtarget assignments
)
1
in_pdb
3LQN
Yes
GBAA4196
47529491
CBS domain-containing protein [Bacillus ...
147
Drug target motif;
Phase 3: June 2008
3LQN
100%
Bacillus anthracis
Unknown function
General
IDP04096
(
show subtarget assignments
)
1
purified
No
YPO2010
115347732
ychF
conserved hypothetical protein [Yersinia...
363
drug target; virulence factor; conserved gene;
Phase 4: April 2009
1JAL
79.6%
Yersinia pestis
Unknown function
General
IDP00174
(
show subtarget assignments
)
1
cloned
No
YPO1140
16121437
-
putative membrane protein
272
Similar to Essential SALTY
Phase 1: October 2007
Yersinia pestis
Unknown function
General
IDP00778
(
show subtarget assignments
)
1
cloned
No
SACOL0668
57284264
hydrolase, alpha/beta hydrolase fold fam...
266
Drug Target Function
Phase 2: March 2008
1VA4
26.1%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP02600
(
show subtarget assignments
)
1
expressed
No
STM2279
16765606
yfaE
2Fe-2S ferredoxin YfaE [Salmonella typhi...
84
Conserved; Drug target functions
Phase 3: June 2008
1IUE
37.2%
Salmonella enterica
Unknown function
General
IDP00173
(
show subtarget assignments
)
1
cloned
No
YPO2922
16123109
-
putative membrane protein
486
Virulence
Phase 1: October 2007
3K4U
14.4%
Yersinia pestis
Unknown function
General
IDP00773
(
show subtarget assignments
)
1
in_crystallization_trials
No
SACOL0569
57285587
ATP:guanido phosphotransferase
335
Drug Target Function
Phase 2: March 2008
3L2D
22.7%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP02584
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM1301
16764652
pyrimidine (deoxy)nucleoside triphosphat...
138
Conserved; Drug target functions
Phase 3: June 2008
2RRK
75.4%
Salmonella enterica
Unknown function
General
IDP00764
(
show subtarget assignments
)
1
expressed
No
SACOL0447
57286820
phosphoglycerate mutase family protein
193
Drug Target Function
Phase 2: March 2008
1C7Z
31.1%
Staphylococcus aureus
Unknown function
General
IDP02587
(
show subtarget assignments
)
1
cloned
No
STM2571
16765891
murQ
N-acetylmuramic acid-6-phosphate etheras...
297
Conserved; Drug target functions
Phase 3: June 2008
1NRI
51.9%
Salmonella enterica
Unknown function
General
IDP02170
(
show subtarget assignments
)
1
soluble
No
FTT1010
56708100
helix-turn-helix family protein [Francis...
67
Drug Target
Phase 3: June 2008
3T75
29.9%
Francisella tularensis
Unknown function
General
IDP02578
(
show subtarget assignments
)
1
expressed
No
STM0262
16763645
yafS
putative SAM-dependent methyltransferase...
240
Conserved; Drug target functions
Phase 3: June 2008
1VLM
11.7%
Salmonella enterica
Unknown function
General
IDP02573
(
show subtarget assignments
)
1
in_pdb
3ICC
No
GBAA1847
47527139
short chain dehydrogenase [Bacillus anth...
252
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
3ICC
100%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP00747
(
show subtarget assignments
)
0
work_stopped
No
SACOL1768
57286203
GAF domain protein
154
Drug Target Function
Phase 2: March 2008
3KSF
98.7%
Staphylococcus aureus
Unknown function
General
IDP04348
(
show subtarget assignments
)
1
cloned
No
CPF_2547
110801206
two component regulator [Clostridium per...
686
viruelnce factor;
Phase 4: April 2009
Clostridium perfringens
Unknown function
General
IDP02163
(
show subtarget assignments
)
1
cloned
No
GBAA3914
47529205
phosphodiesterase [Bacillus anthracis st...
520
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
Bacillus anthracis
Unknown function
General
IDP02160
(
show subtarget assignments
)
1
soluble
No
CBU_1245
29541815
GTP-binding protein [Coxiella burnetii R...
443
Conserved; Drug target functions
Phase 3: June 2008
2HJG
38.4%
Coxiella burnetii
Unknown function
General
IDP00739
(
show subtarget assignments
)
1
diffraction
No
SACOL1063
57284433
acetyltransferase, GNAT family
144
Drug Target Function
Phase 2: March 2008
1Q2Y
40.3%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP00735
(
show subtarget assignments
)
1
purified
No
SACOL0959
57285833
NADH-dependent flavin oxidoreductase, Oy...
375
Drug Target Function
Phase 2: March 2008
3L5A
30.9%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP00081
(
show subtarget assignments
)
1
in_crystallization_trials
No
NT01ST5473
16422973
ytfP
putative cytoplasmic protein
114
Essential
Phase 1: October 2007
1XHS
92.1%
Salmonella enterica
Unknown function
General
IDP01880
(
show subtarget assignments
)
1
in_pdb
3N77
3OGA
Yes
STM2295
16765622
yfaO
putative NTP pyrophosphohydrolase [Salmo...
141
Conserved; Drug target functions
Phase 3: June 2008
3OGA
100%
Salmonella enterica
Unknown function
General
IDP01742
(
show subtarget assignments
)
1
cloned
No
STM3621
16766907
yhjR
putative cytoplasmic protein [Salmonella...
67
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01790
(
show subtarget assignments
)
1
purified
No
FTT1731c
56708736
obgE
GTPase ObgE [Francisella tularensis subs...
334
Drug Target
Phase 3: June 2008
1UDX
45.5%
Francisella tularensis
Unknown function
General
IDP02135
(
show subtarget assignments
)
1
in_pdb
3S81
3S7Z
Yes
STM4510
16767754
putative aspartate racemase [Salmonella ...
244
Conserved; Drug target functions
Phase 3: June 2008
3S7Z
100%
Salmonella enterica
Unknown function
General
IDP02117
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM4356
16767602
yjeF
hypothetical protein STM4356 [Salmonella...
515
Conserved; Drug target functions
Phase 3: June 2008
2AX3
31.3%
Salmonella enterica
Unknown function
General
IDP02120
(
show subtarget assignments
)
1
expressed
No
YPO0027
16120380
phosphatase [Yersinia pestis CO92]
196
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...
Phase 3: June 2008
2B0C
66.8%
Yersinia pestis
Unknown function
General
IDP02514
(
show subtarget assignments
)
1
in_crystallization_trials
No
CBU_0116
29540736
mraW
S-adenosyl-methyltransferase MraW [Coxie...
307
Conserved; Drug target functions
Phase 3: June 2008
1WG8
46.9%
Coxiella burnetii
Unknown function
Enzymes of unknown specificity
IDP02509
(
show subtarget assignments
)
1
crystallized
No
STM1809
16765150
putative cytoplasmic protein [Salmonella...
57
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02140
(
show subtarget assignments
)
1
cloned
No
YPO1629
16121897
N-acetyl-D-glucosamine kinase [Yersinia ...
256
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...
Phase 3: June 2008
2AP1
60.2%
Yersinia pestis
Unknown function
General
IDP02104
(
show subtarget assignments
)
1
soluble
No
YPO1074
16121375
D,D-heptose 1,7-bisphosphate phosphatase...
188
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...
Phase 3: June 2008
2GMW
80.9%
Yersinia pestis
Unknown function
General
IDP01783
(
show subtarget assignments
)
1
expressed
No
FTT0824
56707935
arsC1
arsenate reductase [Francisella tularens...
117
Drug Target
Phase 3: June 2008
3GKX
25.6%
Francisella tularensis
Unknown function
General
IDP02499
(
show subtarget assignments
)
1
in_pdb
3I3O
3IJR
No
GBAA0748
47526031
short chain dehydrogenase [Bacillus anth...
288
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
3I3O
100%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP02100
(
show subtarget assignments
)
1
soluble
No
STM3610
16766896
yhjG
putative inner membrane protein [Salmone...
686
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP00679
(
show subtarget assignments
)
1
in_crystallization_trials
No
SACOL1699
57284711
obgE
GTPase ObgE
430
Drug Target Function
Phase 2: March 2008
1LNZ
54.2%
Staphylococcus aureus
Unknown function
General
IDP01737
(
show subtarget assignments
)
1
soluble
No
STM3690
16766975
putative inner membrane lipoprotein [Sal...
227
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP01786
(
show subtarget assignments
)
1
expressed
No
CBU_0502
29541107
hydrolase, putative [Coxiella burnetii R...
225
Conserved; Drug target functions
Phase 3: June 2008
2GZX
44.9%
Coxiella burnetii
Unknown function
Enzymes of unknown specificity
IDP00673
(
show subtarget assignments
)
1
expressed
No
SACOL1322
57286057
hydrolase, alpha/beta hydrolase fold fam...
304
Drug Target Function
Phase 2: March 2008
3HJU
24.7%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP01873
(
show subtarget assignments
)
1
cloned
No
FTT0917
56708018
maeA
malate dehydrogenase [Francisella tulare...
604
Drug Target
Phase 3: June 2008
2AW5
34.8%
Francisella tularensis
Unknown function
Enzymes of unknown specificity
IDP01904
(
show subtarget assignments
)
1
soluble
No
STM2685
16766000
smpA
hypothetical protein STM2685 [Salmonella...
112
Conserved; Drug target functions
Phase 3: June 2008
2KM7
74.1%
Salmonella enterica
Unknown function
General
IDP00661
(
show subtarget assignments
)
1
purified
No
SACOL0827
57284289
acetyltransferase, putative
161
Drug Target Function
Phase 2: March 2008
1OCX
30.4%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP02456
(
show subtarget assignments
)
1
crystallized
No
GBAA3921
47529213
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
237
Conserved; Essential;
Phase 3: June 2008
2P68
38.1%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP02063
(
show subtarget assignments
)
1
in_crystallization_trials
No
CBU_0387
29540997
cgtA
GTP-binding protein, GTP1/Obg family [Co...
339
Conserved; Drug target functions
Phase 3: June 2008
1UDX
46.3%
Coxiella burnetii
Unknown function
General
IDP02051
(
show subtarget assignments
)
1
cloned
No
STM4141
16767399
putative cytoplasmic protein [Salmonella...
57
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP02050
(
show subtarget assignments
)
1
soluble
No
STM4365
16767611
yjeT
putative inner membrane protein [Salmone...
65
Conserved; Drug target functions
Phase 3: June 2008
Salmonella enterica
Unknown function
General
IDP00071
(
show subtarget assignments
)
0
work_stopped
No
NT01ST2260
16420352
yeaZ
putative molecular chaperone
231
Essential
Phase 1: October 2007
2GEL
100%
Salmonella enterica
Unknown function
General
IDP00649
(
show subtarget assignments
)
1
in_pdb
3R2U
No
SACOL0046
57286601
metallo-beta-lactamase family protein
442
Drug Target Function
Phase 2: March 2008
3R2U
100%
Staphylococcus aureus
Unknown function
Enzymes of unknown specificity
IDP02451
(
show subtarget assignments
)
1
in_pdb
3IMI
No
GBAA1047
47526323
HIT family protein [Bacillus anthracis s...
144
Drug target motif; Involved in sporulation;
Phase 3: June 2008
3IMI
100%
Bacillus anthracis
Unknown function
General
IDP00644
(
show subtarget assignments
)
1
expressed
No
SACOL0220
57286684
flavohemoprotein, putative
381
Conserved Gene / Pathway
Phase 2: March 2008
1CQX
36.9%
Staphylococcus aureus
Unknown function
General
IDP00640
(
show subtarget assignments
)
1
in_pdb
3EME
3MZZ
No
SACOL1807
57286241
rhodanese-like domain protein
103
Drug Target Function
Phase 2: March 2008
3EME
100%
Staphylococcus aureus
Unknown function
General
IDP00638
(
show subtarget assignments
)
1
purified
No
SACOL2736
57285290
gidB
glucose-inhibited division protein B
239
Drug Target Function
Phase 2: March 2008
1XDZ
63.2%
Staphylococcus aureus
Unknown function
General
IDP00636
(
show subtarget assignments
)
1
cloned
No
SACOL1118
57285904
typA
GTP-binding protein TypA
615
Drug Target Function
Phase 2: March 2008
3E3X
27.6%
Staphylococcus aureus
Unknown function
General
IDP02438
(
show subtarget assignments
)
1
cloned
No
CBU_0029
29540654
acyltransferase family protein [Coxiella...
242
Conserved; Drug target functions
Phase 3: June 2008
Coxiella burnetii
Unknown function
Enzymes of unknown specificity
IDP02430
(
show subtarget assignments
)
1
expressed
No
FTT1151c
56708222
hypothetical protein FTT1151c [Francisel...
95
Drug Target
Phase 3: June 2008
2JR5
25.3%
Francisella tularensis
Unknown function
General
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