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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 15 of 60, showing 100 records out of 5973 total, starting on record 1401
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP00071
(
show subtarget assignments
)
0
work_stopped
No
NT01ST2260
16420352
yeaZ
putative molecular chaperone
231
Essential
Phase 1: October 2007
2GEL
100%
Salmonella enterica
Unknown function
General
IDP00511
(
show subtarget assignments
)
1
in_pdb
3RPE
No
YPO0670
16120995
mdaB
putative modulator of drug activity
194
Conserved Gene / Pathway
Phase 2: March 2008
3RPE
100%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP05412
(
show subtarget assignments
)
1
soluble
No
BA_3584
30258112
putative microbial collagenase [Bacillus...
971
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2Y3U
38.9%
Bacillus anthracis
Protein fate: Degradation of proteins, peptides, and glycopeptides
IDP90718
(
show subtarget assignments
)
8
in_pdb
3N4J
3N4K
No
YPO0071
16120422
putative methyltransferase [Yersinia pes...
162
Predicted Essential
Community Requests
3N4J
100%
Yersinia pestis
IDP02658
(
show subtarget assignments
)
1
cloned
No
STM2648
16765968
yfiF
putative methyltransferase [Salmonella t...
345
Conserved; Essential; Drug target functions
Phase 3: June 2008
1X7O
20.6%
Salmonella enterica
Unknown function
General
IDP02252
(
show subtarget assignments
)
1
soluble
No
YPO1229
16121516
tsr2
putative methyl-accepting chemotaxis pro...
595
Conserved; Drug target functions
Phase 3: June 2008
3ZX6
27.4%
Yersinia pestis
Cellular processes
Chemotaxis and motility
IDP01957
(
show subtarget assignments
)
1
expressed
No
STM1657
16765001
putative methyl-accepting chemotaxis pro...
384
Conserved; Drug target functions
Phase 3: June 2008
3ZX6
32.6%
Salmonella enterica
Cellular processes
Chemotaxis and motility
IDP02076
(
show subtarget assignments
)
1
soluble
No
STM3216
16766515
putative methyl-accepting chemotaxis pro...
521
Conserved; Drug target functions
Phase 3: June 2008
3ZX6
28.6%
Salmonella enterica
Cellular processes
Chemotaxis and motility
IDP01047
(
show subtarget assignments
)
1
cloned
No
STM3152
16766452
putative methyl-accepting chemotaxis pro...
547
Conserved Gene / Pathway
Phase 2: March 2008
3ZX6
34.7%
Salmonella enterica
Cellular processes
Chemotaxis and motility
IDP01046
(
show subtarget assignments
)
1
expressed
No
STM3138
16766438
putative methyl-accepting chemotaxis pro...
352
Conserved Gene / Pathway
Phase 2: March 2008
1QU7
16.8%
Salmonella enterica
Cellular processes
Other
IDP01897
(
show subtarget assignments
)
1
expressed
No
STM3038
16766339
putative metalloendopeptidase [Salmonell...
252
Drug target motif; Conserved; Drug target functions
Phase 3: June 2008
2GU1
18.3%
Salmonella enterica
Cell envelope
Other
IDP00181
(
show subtarget assignments
)
1
soluble
No
YPO0363
16120698
-
putative membrane transport protein
1119
Similar to Essential SALTY
Phase 1: October 2007
2OAU
5%
Yersinia pestis
DNA metabolism
DNA replication, recombination, and repair
IDP00221
(
show subtarget assignments
)
1
soluble
No
YPO0164
16120507
-
putative membrane receptor protein
686
Virulence
Phase 1: October 2007
2HDF
20.1%
Yersinia pestis
Cell envelope
Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP04460
(
show subtarget assignments
)
1
expressed
No
YPO1482
115347233
putative membrane protein [Yersinia pest...
1140
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Cell envelope
Other
IDP04487
(
show subtarget assignments
)
1
expressed
No
YPO3598
115349219
putative membrane protein [Yersinia pest...
255
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
3U66
17.3%
Yersinia pestis
Cell envelope
Other
IDP04729
(
show subtarget assignments
)
1
cloned
No
YPO0515
115346325
putative membrane protein [Yersinia pest...
1150
virulence factor; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Unclassified
Role category not yet assigned
IDP00224
(
show subtarget assignments
)
1
cloned
No
YPO3058
16123235
-
putative membrane protein
288
Virulence
Phase 1: October 2007
Yersinia pestis
Mobile and extrachromosomal element functions
Transposon functions
IDP00204
(
show subtarget assignments
)
1
expressed
No
YPO1702
16121962
-
putative membrane protein
450
Virulence
Phase 1: October 2007
Yersinia pestis
Hypothetical proteins
Conserved
IDP00202
(
show subtarget assignments
)
1
soluble
No
YPO2731
16122935
-
putative membrane protein
679
Virulence
Phase 1: October 2007
Yersinia pestis
Cell envelope
Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP00196
(
show subtarget assignments
)
1
cloned
No
YPO1051
16121351
-
putative membrane protein
451
Virulence
Phase 1: October 2007
2ZPL
13.5%
Yersinia pestis
IDP00194
(
show subtarget assignments
)
1
cloned
No
YPO0983
16121287
-
putative membrane protein
216
Virulence
Phase 1: October 2007
Yersinia pestis
Hypothetical proteins
Conserved
IDP00186
(
show subtarget assignments
)
1
soluble
No
YPO0695
16121016
-
putative membrane protein
140
Virulence
Phase 1: October 2007
Yersinia pestis
Transport and binding proteins
Carbohydrates, organic alcohols, and acids
IDP00184
(
show subtarget assignments
)
1
cloned
No
YPO0624
16120950
-
putative membrane protein
483
Virulence
Phase 1: October 2007
Yersinia pestis
Hypothetical proteins
Conserved
IDP00177
(
show subtarget assignments
)
1
purified
No
YPO3007
16123186
-
putative membrane protein
509
Virulence
Phase 1: October 2007
Yersinia pestis
Cell envelope
Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP00174
(
show subtarget assignments
)
1
cloned
No
YPO1140
16121437
-
putative membrane protein
272
Similar to Essential SALTY
Phase 1: October 2007
Yersinia pestis
Unknown function
General
IDP00173
(
show subtarget assignments
)
1
cloned
No
YPO2922
16123109
-
putative membrane protein
486
Virulence
Phase 1: October 2007
3K4U
14.4%
Yersinia pestis
Unknown function
General
IDP04145
(
show subtarget assignments
)
1
expressed
No
YPO3422
115349050
ampE
putative membrane-bound sensory transduc...
284
conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP00172
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO2438
16122659
-
putative membrane-bound lytic murein tra...
220
Virulence
Phase 1: October 2007
2Y8P
42.7%
Yersinia pestis
Mobile and extrachromosomal element functions
Prophage functions
IDP05187
(
show subtarget assignments
)
1
cloned
No
CD0199
126697770
putative membrane-associated nucleotidas...
476
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3GVE
19.5%
Clostridium difficile
Cell envelope: Other
IDP05226
(
show subtarget assignments
)
1
cloned
No
lmo0460
16802504
-
putative membrane associated lipoprotein...
689
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3RGX
11.8%
Listeria monocytogenes
Hypothetical proteins: Conserved
IDP05114
(
show subtarget assignments
)
1
cloned
No
CD2537
126700154
putative membrane-associated 5'-nucleoti...
605
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3IVD
25.1%
Clostridium difficile
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
IDP04480
(
show subtarget assignments
)
1
selected
No
YPO3104
218930142
wbyK
putative mannosyltransferase [Yersinia p...
337
drug target; virulence factor; putative drug target function;
Phase 4: April 2009
2BIS
25.1%
Yersinia pestis
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP05623
(
show subtarget assignments
)
1
soluble
No
CD1034
126698618
putative mannosyl-glycoprotein endo-beta...
324
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3FI7
17.3%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP04377
(
show subtarget assignments
)
1
soluble
No
CPF_2652
110798678
putative maltose/maltodextrin ABC transp...
408
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1URG
38.7%
Clostridium perfringens
Transport and binding proteins
Carbohydrates, organic alcohols, and acids
IDP00209
(
show subtarget assignments
)
1
soluble
No
YPO2062
16122301
-
putative M23/M37 peptidase-family protei...
417
Virulence
Phase 1: October 2007
2GU1
32.4%
Yersinia pestis
Cellular processes
Chemotaxis and motility
IDP05488
(
show subtarget assignments
)
1
cloned
No
BA_4789
30259275
putative LPXTG-motif cell wall anchor do...
237
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2K78
22.8%
Bacillus anthracis
Unknown function: General
IDP00199
(
show subtarget assignments
)
1
purified
No
YPO1431
16121710
-
putative Lon protease
590
Virulence
Phase 1: October 2007
3K1J
17.6%
Yersinia pestis
Protein synthesis
Ribosomal proteins: synthesis and modification
IDP04317
(
show subtarget assignments
)
1
cloned
No
YPO0512
218927711
putative lipoprotein [Yersinia pestis CO...
163
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Cell envelope
Other
IDP91483
(
show subtarget assignments
)
8
cloned
No
VP1700
28898474
putative lipoprotein VirG [Vibrio paraha...
138
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio parahaemolyticus
IDP05547
(
show subtarget assignments
)
1
soluble
No
lmo0285
16802331
-
putative lipoprotein [Listeria monocytog...
273
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3TQW
41%
Listeria monocytogenes
Unclassified: Role category not yet assigned
IDP04307
(
show subtarget assignments
)
1
cloned
No
CPF_1812
110799901
putative lipoprotein [Clostridium perfri...
44
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
IDP04566
(
show subtarget assignments
)
1
expressed
No
CPF_1876
110800623
putative lipoprotein [Clostridium perfri...
221
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04518
(
show subtarget assignments
)
1
cloned
No
CPF_2883
110799727
putative lipoprotein [Clostridium perfri...
361
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04562
(
show subtarget assignments
)
1
cloned
No
CPF_1080
110798737
putative lipoprotein [Clostridium perfri...
185
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04207
(
show subtarget assignments
)
1
soluble
No
CPF_2836
110801144
putative lipoprotein [Clostridium perfri...
279
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04197
(
show subtarget assignments
)
1
expressed
No
CPF_2510
110799662
putative lipoprotein [Clostridium perfri...
237
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04564
(
show subtarget assignments
)
1
cloned
No
CPF_1610
110800230
putative lipoprotein [Clostridium perfri...
125
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04052
(
show subtarget assignments
)
1
cloned
No
CPF_0049
110799596
putative lipoprotein [Clostridium perfri...
167
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04006
(
show subtarget assignments
)
1
cloned
No
CPF_1351
110800739
putative lipoprotein [Clostridium perfri...
264
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04196
(
show subtarget assignments
)
1
cloned
No
CPF_2502
110800817
putative lipoprotein [Clostridium perfri...
507
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04392
(
show subtarget assignments
)
1
cloned
No
CPF_1500
110798925
putative lipoprotein [Clostridium perfri...
202
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04233
(
show subtarget assignments
)
1
cloned
No
CPF_0722
110798767
putative lipoprotein [Clostridium perfri...
384
drug target; putative drug target function;
Phase 4: April 2009
2UVK
16.1%
Clostridium perfringens
Cell envelope
Other
IDP04017
(
show subtarget assignments
)
1
cloned
No
CPF_1035
110799411
putative lipoprotein [Clostridium perfri...
309
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04088
(
show subtarget assignments
)
1
soluble
No
CPF_2931
110800177
putative lipoprotein [Clostridium perfri...
184
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04254
(
show subtarget assignments
)
1
cloned
No
CPF_1823
110798846
putative lipoprotein [Clostridium perfri...
233
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04200
(
show subtarget assignments
)
1
expressed
No
CPF_0244
110798897
putative lipoprotein [Clostridium perfri...
440
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04063
(
show subtarget assignments
)
1
cloned
No
CPF_0514
110800714
putative lipoprotein [Clostridium perfri...
176
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04565
(
show subtarget assignments
)
1
cloned
No
CPF_1805
110798813
putative lipoprotein [Clostridium perfri...
281
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04567
(
show subtarget assignments
)
1
cloned
No
CPF_2099
110800052
putative lipoprotein [Clostridium perfri...
343
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04329
(
show subtarget assignments
)
1
expressed
No
CPF_1466
110801108
putative lipoprotein [Clostridium perfri...
483
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04252
(
show subtarget assignments
)
1
cloned
No
CPF_1780
110799805
putative lipoprotein [Clostridium perfri...
445
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04091
(
show subtarget assignments
)
1
cloned
No
CPF_1278
110799680
putative lipoprotein [Clostridium perfri...
155
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP04412
(
show subtarget assignments
)
1
cloned
No
CPF_0435
110799959
putative lipoprotein [Clostridium perfri...
431
drug target; putative drug target function;
Phase 4: April 2009
Clostridium perfringens
Cell envelope
Other
IDP05625
(
show subtarget assignments
)
1
soluble
No
CD1348
126698947
putative lipoprotein [Clostridium diffic...
178
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05515
(
show subtarget assignments
)
1
cloned
No
CD1687
126699293
putative lipoprotein [Clostridium diffic...
278
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05506
(
show subtarget assignments
)
1
soluble
No
CD1232
126698828
putative lipoprotein [Clostridium diffic...
273
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1NA0
15.8%
Clostridium difficile
Unknown function: General
IDP02461
(
show subtarget assignments
)
1
cloned
No
Cj0176c
15791563
putative lipoprotein [Campylobacter jeju...
43
Predicted virulence-Iron Scavenging Mechanisms
Phase 3: June 2008
Campylobacter jejuni
Transport and binding proteins
Cations and iron carrying compounds
IDP02737
(
show subtarget assignments
)
1
expressed
No
GBAA1974
47527269
putative lipoprotein [Bacillus anthracis...
415
Drug target motif; Drug target functions
Phase 3: June 2008
Bacillus anthracis
Cell envelope
Other
IDP05614
(
show subtarget assignments
)
1
soluble
No
BA_5326
30259802
putative lipoprotein [Bacillus anthracis...
321
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05029
(
show subtarget assignments
)
1
cloned
No
BA_0864
30254614
putative lipoprotein [Bacillus anthracis...
198
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05596
(
show subtarget assignments
)
1
cloned
No
BA_3366
30257909
putative lipoprotein [Bacillus anthracis...
278
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05014
(
show subtarget assignments
)
1
soluble
No
BA_1972
30256627
putative lipoprotein [Bacillus anthracis...
765
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05276
(
show subtarget assignments
)
1
soluble
No
BA_4236
30258739
putative lipoprotein [Bacillus anthracis...
146
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05592
(
show subtarget assignments
)
1
cloned
No
BA_3194
30257761
putative lipoprotein [Bacillus anthracis...
160
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05007
(
show subtarget assignments
)
1
cloned
No
BA_3383
30257926
putative lipoprotein [Bacillus anthracis...
236
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05607
(
show subtarget assignments
)
1
soluble
No
BA_4862
30259361
putative lipoprotein [Bacillus anthracis...
123
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2JQO
23.6%
Bacillus anthracis
Cell envelope: Other
IDP05469
(
show subtarget assignments
)
1
soluble
No
BA_2398
30257029
putative lipoprotein [Bacillus anthracis...
177
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05718
(
show subtarget assignments
)
1
expressed
No
BA_1601
30255901
putative lipoprotein [Bacillus anthracis...
103
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05405
(
show subtarget assignments
)
1
expressed
No
BA_0837
30254426
putative lipoprotein [Bacillus anthracis...
179
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3K0Z
78.2%
Bacillus anthracis
Cell envelope: Other
IDP05589
(
show subtarget assignments
)
1
soluble
No
BA_2931
30257523
putative lipoprotein [Bacillus anthracis...
149
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05016
(
show subtarget assignments
)
1
soluble
No
BA_2056
30256706
putative lipoprotein [Bacillus anthracis...
59
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05437
(
show subtarget assignments
)
1
expressed
No
BA_2898
30257493
putative lipoprotein [Bacillus anthracis...
120
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05183
(
show subtarget assignments
)
1
soluble
No
BA_5237
30259716
putative lipoprotein [Bacillus anthracis...
176
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05442
(
show subtarget assignments
)
1
cloned
No
BA_0171
30253680
putative lipoprotein [Bacillus anthracis...
113
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05017
(
show subtarget assignments
)
1
cloned
No
BA_2521
30257145
putative lipoprotein [Bacillus anthracis...
52
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05006
(
show subtarget assignments
)
1
cloned
No
BA_3083
30257668
putative lipoprotein [Bacillus anthracis...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05009
(
show subtarget assignments
)
1
soluble
No
BA_4237
30258740
putative lipoprotein [Bacillus anthracis...
253
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05612
(
show subtarget assignments
)
1
soluble
No
BA_5233
30259713
putative lipoprotein [Bacillus anthracis...
129
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05615
(
show subtarget assignments
)
1
soluble
No
BA_5522
30259982
putative lipoprotein [Bacillus anthracis...
126
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05001
(
show subtarget assignments
)
1
purified
No
BA_1090
30254820
putative lipoprotein [Bacillus anthracis...
142
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05049
(
show subtarget assignments
)
1
soluble
No
BA_5058
30259547
putative lipoprotein [Bacillus anthracis...
271
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05507
(
show subtarget assignments
)
1
cloned
No
BA_5374
30259847
putative lipoprotein [Bacillus anthracis...
161
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05395
(
show subtarget assignments
)
1
cloned
No
BA_2942
30257534
putative lipoprotein [Bacillus anthracis...
86
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05313
(
show subtarget assignments
)
1
soluble
No
BA_1061
30254794
putative lipoprotein [Bacillus anthracis...
274
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05580
(
show subtarget assignments
)
1
soluble
No
BA_0936
30254679
putative lipoprotein [Bacillus anthracis...
138
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05045
(
show subtarget assignments
)
1
soluble
No
BA_3418
30257959
putative lipoprotein [Bacillus anthracis...
131
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05590
(
show subtarget assignments
)
1
soluble
No
BA_2986
30257575
putative lipoprotein [Bacillus anthracis...
189
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05476
(
show subtarget assignments
)
1
soluble
No
BA_2745
30257350
putative lipoprotein [Bacillus anthracis...
117
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05486
(
show subtarget assignments
)
1
soluble
No
BA_4573
30259076
putative lipoprotein [Bacillus anthracis...
155
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05460
(
show subtarget assignments
)
1
cloned
No
BA_0985
30254723
putative lipoprotein [Bacillus anthracis...
153
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
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Filter Columns:
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