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Targets
Filter Targets:
Selection Phase:
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Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 15 of 60, showing 100 records out of 5973 total, starting on record 1401
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90912
(
show subtarget assignments
)
8
purified
No
YPO1603
16121871
4-amino-4-deoxychorismate lyase [Yersini...
268
Predicted Essential
Community Requests
1ET0
56%
Yersinia pestis
IDP90913
(
show subtarget assignments
)
8
soluble
No
VC1182
15641195
thioredoxin reductase [Vibrio cholerae O...
318
Predicted Essential
Community Requests
1CL0
81.4%
Vibrio cholerae
IDP90916
(
show subtarget assignments
)
8
soluble
No
YPO3073
16123250
cysS
cysteinyl-tRNA synthetase [Yersinia pest...
461
Predicted Essential
Community Requests
1LI5
83.9%
Yersinia pestis
IDP90917
(
show subtarget assignments
)
8
expressed
No
Q9KV30
41019520
RecName: Full=DNA-directed RNA polymeras...
1341
Predicted Essential
Community Requests
3IYD
85.3%
Vibrio cholerae
IDP90919
(
show subtarget assignments
)
8
expressed
No
YPO2608
16122821
holA
DNA polymerase III subunit delta [Yersin...
344
Predicted Essential
Community Requests
1JQJ
71.5%
Yersinia pestis
IDP90920
(
show subtarget assignments
)
8
expressed
No
VC0021
15640053
glyQ
glycyl-tRNA synthetase subunit alpha [Vi...
330
Predicted Essential
Community Requests
3RF1
56.4%
Vibrio cholerae
IDP00088
(
show subtarget assignments
)
8
in_crystallization_trials
No
NT01ST3082
16421025
dapE
N-succinyl-diaminopimelate deacylase
375
Essential
Community Requests
3IC1
61.9%
Salmonella enterica
Amino acid biosynthesis
Aspartate family
IDP90928
(
show subtarget assignments
)
8
soluble
No
VC2245
15642243
dnaE
DNA polymerase III subunit alpha [Vibrio...
1164
Predicted Essential
Community Requests
2HQA
62.5%
Vibrio cholerae
IDP90930
(
show subtarget assignments
)
8
cloned
No
YPO3384
16123533
mtn
5'-methylthioadenosine/S-adenosylhomocys...
233
Predicted Essential
Community Requests
1JYS
74.7%
Yersinia pestis
IDP90931
(
show subtarget assignments
)
8
soluble
No
STM1337
16764688
pheS
phenylalanyl-tRNA synthetase subunit alp...
327
Predicted Essential
Community Requests
3PCO
97.6%
Salmonella enterica
IDP90934
(
show subtarget assignments
)
8
crystallized
No
YPO0480
16120810
dapB
dihydrodipicolinate reductase [Yersinia ...
273
Predicted Essential
Community Requests
1ARZ
79.5%
Yersinia pestis
IDP90935
(
show subtarget assignments
)
8
cloned
No
YPO3313
16123466
C-terminal region of transketolase [Yers...
314
Predicted Essential
Community Requests
2O1S
28.7%
Yersinia pestis
IDP90937
(
show subtarget assignments
)
8
cloned
No
YPO0110
16120456
priA
primosome assembly protein PriA
732
Predicted Essential
Community Requests
2EYQ
9.4%
Yersinia pestis
IDP90938
(
show subtarget assignments
)
8
cloned
No
NMPDR 243277.1.peg.3917
218
Predicted Essential
Community Requests
2JGV
22.5%
Vibrio cholerae
IDP90942
(
show subtarget assignments
)
8
expressed
No
A55_2372
124113375
ispE
4-diphosphocytidyl-2C-methyl-D-erythrito...
194
We have identified the methylerythritol phosphate (MEP) pathway enzymes, novel d...
Community Requests
1OJ4
59.8%
Vibrio cholerae
IDP90943
(
show subtarget assignments
)
8
purified
No
BAS0032
49183067
DNA replication intiation control protei...
121
This is an essential protein that connects DNA replication to cell growth by bin...
Community Requests
Bacillus anthracis
IDP90945
(
show subtarget assignments
)
8
purified
No
VP0092
28896866
hypothetical protein VP0092 [Vibrio para...
811
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3HVB
13.7%
Vibrio parahaemolyticus
IDP90946
(
show subtarget assignments
)
8
cloned
No
BP1878
33592926
bvgA
virulence factors transcription regulato...
209
BvgA is the transcriptional activator for all known virulence genes in the human...
Community Requests
3C3W
31.6%
Bordetella pertussis
IDP90949
(
show subtarget assignments
)
8
purified
No
ZZZ_0019
20986512
MAPK14
mitogen-activated protein kinase 14 isof...
360
Drug Target
Community Requests
1A9U
100%
Homo sapiens
IDP90950
(
show subtarget assignments
)
8
soluble
No
ZZZ_0018
51094326
MAPK-1
mitogen-activated protein kinase 1
532
Drug Target Homolog
Community Requests
3OHT
30.1%
Toxoplasma gondii
IDP90952
(
show subtarget assignments
)
8
soluble
No
UTI89_C2726
122422986
Hypothetical protein yfeA
749
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
13.4%
Escherichia coli
IDP90953
(
show subtarget assignments
)
8
expressed
No
VF0985
75354249
Sensory box/GGDEF family protein
827
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3HVB
12.1%
Vibrio fischeri
IDP90958
(
show subtarget assignments
)
8
cloned
No
UTI89_C1702
122423767
Hypothetical protein
807
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
1V9Y
18%
Escherichia coli
IDP90959
(
show subtarget assignments
)
8
cloned
No
PP2258
81441302
Sensory box protein
562
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
2R6O
20.6%
Pseudomonas putida
IDP90961
(
show subtarget assignments
)
8
purified
No
VP0117
81728759
GGDEF family protein
848
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
12.3%
Vibrio parahaemolyticus
IDP90962
(
show subtarget assignments
)
8
purified
No
VC2750
81544306
GGDEF family protein
849
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
2R6O
13%
Vibrio cholerae
IDP90965
(
show subtarget assignments
)
8
purified
No
VF0094
75354809
Sensory box/GGDEF family protein
852
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
11.2%
Vibrio fischeri
IDP90966
(
show subtarget assignments
)
8
purified
No
UTI89_C3683
122422243
Hypothetical protein yhdA
646
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3HVB
15.8%
Escherichia coli
IDP90968
(
show subtarget assignments
)
8
selected
No
427
Planet Biotechnology company is currently developing an anthrax anti-toxin with ...
Community Requests
1HZH
62.3%
synthetic construct
IDP90972
(
show subtarget assignments
)
8
selected
No
ECO103_4485
260846542
tisB
lexA-regulated toxic peptide [Escherichi...
29
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Escherichia coli
IDP90977
(
show subtarget assignments
)
8
soluble
No
y0320
22124237
oxyR
DNA-binding transcriptional regulator Ox...
305
other biological interest /
important global regulator
Community Requests
1I6A
59.7%
Yersinia pestis
IDP90978
(
show subtarget assignments
)
8
selected
No
y0549
22124463
hypothetical protein y0549 [Yersinia pes...
162
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP90980
(
show subtarget assignments
)
8
cloned
No
y0801
22124714
iron-sulfur cluster insertion protein Er...
119
other biological interest /
protein possibly involved in iron-sulfur cluster synthesis
Community Requests
2APN
75.6%
Yersinia pestis
IDP90981
(
show subtarget assignments
)
8
selected
No
y0850
22124761
outer membrane receptor [Yersinia pestis...
731
other biological interest /
putative iron-binding TonB-dependent outer membrane receptor
Community Requests
2HDF
31.1%
Yersinia pestis
IDP90984
(
show subtarget assignments
)
8
cloned
No
y0931
22124839
hypothetical protein y0931 [Yersinia pes...
281
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3SHO
12.8%
Yersinia pestis
IDP90985
(
show subtarget assignments
)
8
expressed
No
y0964
22124871
hypothetical protein y0964 [Yersinia pes...
421
other biological interest /
-
Community Requests
3MVE
41.8%
Yersinia pestis
IDP90987
(
show subtarget assignments
)
8
crystallized
No
y1125
22125029
hypothetical protein y1125 [Yersinia pes...
297
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
1VP5
57.2%
Yersinia pestis
IDP90988
(
show subtarget assignments
)
8
expressed
No
y1189
22125092
gltI
glutamate and aspartate transporter subu...
305
other biological interest /
-
Community Requests
2IA4
75.7%
Yersinia pestis
IDP90994
(
show subtarget assignments
)
8
purified
No
y1355
22125254
hypothetical protein y1355 [Yersinia pes...
211
other biological interest /
-
Community Requests
Yersinia pestis
IDP90995
(
show subtarget assignments
)
8
in_crystallization_trials
No
y1430
22125328
hypothetical protein y1430 [Yersinia pes...
369
other biological interest /
putative periplasmic iron-binding protein
Community Requests
3C9H
33.1%
Yersinia pestis
IDP90997
(
show subtarget assignments
)
8
soluble
No
y1682
22125577
ompX
outer membrane protein X [Yersinia pesti...
176
virulence/pathogenesis /
putative cell surface adhesin in various Gram-negative pathogens
Community Requests
1ORM
59.1%
Yersinia pestis
IDP90998
(
show subtarget assignments
)
8
cloned
No
y1724
22125618
hypothetical protein y1724 [Yersinia pes...
448
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91001
(
show subtarget assignments
)
8
soluble
No
y1897
22125790
yfeA
periplasmic-binding protein [Yersinia pe...
323
virulence/pathogenesis /
periplasmic iron-binding protein
Community Requests
1XVL
52.9%
Yersinia pestis
IDP91002
(
show subtarget assignments
)
8
selected
No
y1919
22125812
bifunctional UDP-glucuronic acid decarbo...
667
virulence/pathogenesis /
-
Community Requests
1Z7E
70.2%
Yersinia pestis
IDP91004
(
show subtarget assignments
)
8
soluble
No
y1935
22125827
cysteine desulfurase activator complex s...
503
potential drug target /
part of iron-sulfur cluster assembly system active under stress conditions
Community Requests
4DN7
18.7%
Yersinia pestis
IDP91005
(
show subtarget assignments
)
8
soluble
No
y1936
22125828
ATP-binding component of a transport sys...
257
potential drug target /
part of iron-sulfur cluster assembly system active under stress conditions
Community Requests
2ZU0
80.9%
Yersinia pestis
IDP91009
(
show subtarget assignments
)
8
soluble
No
y2136
22126024
hypothetical protein y2136 [Yersinia pes...
317
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91010
(
show subtarget assignments
)
8
cloned
No
y2245
22126131
hypothetical protein y2245 [Yersinia pes...
341
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3ETN
12.3%
Yersinia pestis
IDP91012
(
show subtarget assignments
)
8
expressed
No
y2259
22126145
hypothetical protein y2259 [Yersinia pes...
271
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91013
(
show subtarget assignments
)
8
selected
No
y2358
22126242
hmsF
outer membrane N-deacetylase [Yersinia p...
673
interesting protein in the context of biofilm formation in Y pestis
Community Requests
Yersinia pestis
IDP91016
(
show subtarget assignments
)
8
selected
No
y2451
22126334
hypothetical protein y2451 [Yersinia pes...
384
other biological interest /
putative iron transport protein
Community Requests
3AT7
40.9%
Yersinia pestis
IDP91017
(
show subtarget assignments
)
8
expressed
No
y2556
22126437
fcuA
ferrichrome receptor, TonB dependent [Ye...
776
other biological interest /
putative iron-binding TonB-dependent outer membrane receptor
Community Requests
3QLB
23.6%
Yersinia pestis
IDP91019
(
show subtarget assignments
)
8
selected
No
y2821
22126698
poxB
pyruvate dehydrogenase [Yersinia pestis ...
573
potential drug target /
alternative pathway for aerobic energy metabolism
Community Requests
3EY9
79.2%
Yersinia pestis
IDP91020
(
show subtarget assignments
)
8
in_crystallization_trials
No
y2842
22126718
hypothetical protein y2842 [Yersinia pes...
378
other biological interest /
putative periplasmic iron-binding protein
Community Requests
2ETV
22.8%
Yersinia pestis
IDP91025
(
show subtarget assignments
)
8
in_crystallization_trials
No
y3037
22126914
modA
molybdate transporter periplasmic protei...
263
other biological interest /
-
Community Requests
3R26
63.9%
Yersinia pestis
IDP91026
(
show subtarget assignments
)
8
cloned
No
y3142
22127018
flavodoxin [Yersinia pestis KIM 10]
149
other biological interest /
oxidative stress response protein
Community Requests
2HNA
33.6%
Yersinia pestis
IDP91028
(
show subtarget assignments
)
8
selected
No
y3714
22127588
hypothetical protein y3714 [Yersinia pes...
259
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91029
(
show subtarget assignments
)
8
soluble
No
y3772
22127643
LACI-type transcriptional regulator [Yer...
374
other biological interest /
part of the autoinducer II transport system (quorum sensing)
Community Requests
3T95
84%
Yersinia pestis
IDP91032
(
show subtarget assignments
)
8
cloned
No
Y1069
31795399
toxin [Yersinia pestis KIM]
587
virulence/pathogenesis /
survival factor of Y pestis in the flea
Community Requests
1F0I
22.7%
Yersinia pestis
IDP91033
(
show subtarget assignments
)
8
cloned
No
SAR0023
49240405
sasH
putative 5'-nucleotidase [Staphylococcus...
786
virulence/pathogenesis /
An uncharacterized cell surface protein of staph. aureus with an anchor site for...
Community Requests
2Z1A
22.5%
Staphylococcus aureus
IDP91035
(
show subtarget assignments
)
8
selected
No
SDY_P070
82524476
ospC2
OspC2 [Shigella dysenteriae Sd197]
484
virulence/pathogenesis /
A cell surface protein of S. dysenteriae and putative virulence factor secreted ...
Community Requests
Shigella dysenteriae
IDP91036
(
show subtarget assignments
)
8
selected
No
SDY_P151
82524557
ospC3
OspC3 [Shigella dysenteriae Sd197]
484
virulence/pathogenesis /
A cell surface protein of S. dysenteriae and putative virulence factor secreted ...
Community Requests
Shigella dysenteriae
IDP91041
(
show subtarget assignments
)
8
in_pdb
3TYS
3TYR
No
EFE0002
33355847
vanUG
predicted transcriptional regulator [Ent...
75
drug resistance /
Putative transcriptional regulator
Community Requests
3T75
89.3%
Enterococcus faecalis
IDP91042
(
show subtarget assignments
)
8
in_crystallization_trials
No
ACB0002
38230268
AdeR [Acinetobacter baumannii]
247
Regulator protein of transcription of antibiotic drug-efflux pump AdeABC
Community Requests
2GWR
33.2%
Acinetobacter baumannii
IDP91044
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFA0002
110556113
vanY
vanY [Enterococcus faecalis]
303
drug resistance /
A carboxypeptidase thought to be involved in breakdown of normal cell wall
Community Requests
Enterococcus faecalis
IDP91045
(
show subtarget assignments
)
8
cloned
No
ECH0010
15799700
hypothetical protein Z0021 [Escherichia ...
108
virulence/pathogenesis /
Hypothetical protein Z0021 is involved in regulation of swimming motility in E. ...
Community Requests
Escherichia coli
IDP91048
(
show subtarget assignments
)
8
in_crystallization_trials
No
EGA0001
4545123
vanT
serine racemase VanT [Enterococcus galli...
698
drug resistance /
Serine racemase involved in synthesis of D-Ala-D-Ser, a component of vancomycin ...
Community Requests
4ECL
22.3%
Enterococcus gallinarum
IDP91049
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFE0005
160947043
vanTrL
serine racemase [Enterococcus faecalis]
366
drug resistance /
Soluble component of serine racemase involved in synthesis of vancomycin resista...
Community Requests
4ECL
42.6%
Enterococcus faecalis
IDP91052
(
show subtarget assignments
)
8
in_crystallization_trials
No
PSA0001
116063829
rmtD
16S rRNA methylase [Pseudomonas aerugino...
247
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3B89
42.5%
Pseudomonas aeruginosa
IDP91051
(
show subtarget assignments
)
8
in_crystallization_trials
No
PRM0001
81687074
rmtC
16S rRNA methylase [Proteus mirabilis]
281
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3B89
29.2%
Proteus mirabilis
IDP91059
(
show subtarget assignments
)
8
soluble
No
FTT_1472c
56708512
ppiC
peptidyl-prolyl cis-trans isomerase [Fra...
92
virulence/pathogenesis /
Gene encodes a SurA orthologue which has shown to be important for virulence in ...
Community Requests
1JNS
47.8%
Francisella tularensis
IDP91061
(
show subtarget assignments
)
8
purified
No
YPO3532
16123678
fklB
FKBP-type peptidyl-prolyl cis-trans isom...
206
virulence/pathogenesis /
Gene encodes a Mip orthologue which has shown to be important for virulence in v...
Community Requests
1FD9
38.8%
Yersinia pestis
IDP91065
(
show subtarget assignments
)
8
expressed
No
VC0395_A0354
147674291
tcpB
toxin co-regulated pilus biosynthesis pr...
430
vaccine candidate /
For Vibrio cholerae to colonize the human intestine and cause cholera, it must e...
Community Requests
Vibrio cholerae
IDP91068
(
show subtarget assignments
)
8
cloned
No
VF_A0424
59713607
msbA
lipid transporter ATP-binding/permease p...
582
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5X
75.1%
Vibrio fischeri
IDP91071
(
show subtarget assignments
)
8
cloned
No
NGO2165
59719354
putative ABC transporter, ATP-binding pr...
622
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5Y
34.2%
Neisseria gonorrhoeae
IDP91072
(
show subtarget assignments
)
8
cloned
No
YPO2588
16122801
-
putative ABC transport protein
631
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
32.2%
Yersinia pestis
IDP91074
(
show subtarget assignments
)
8
cloned
No
MSMEG_5659
118469658
ABC transporter, ATP-binding protein [My...
610
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
32.1%
Mycobacterium smegmatis
IDP91075
(
show subtarget assignments
)
8
cloned
No
jhp0343
15611411
msbA
multi-drug resistance protein [Helicobac...
551
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5W
31.4%
Helicobacter pylori
IDP91079
(
show subtarget assignments
)
8
cloned
No
BMA0204
53725011
ABC transporter, ATP-binding/permease pr...
623
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
4AA3
32.8%
Burkholderia mallei
IDP91080
(
show subtarget assignments
)
8
cloned
No
Cj0803
6968244
msbA
lipid export ABC transport protein
580
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
31.6%
Campylobacter jejuni
IDP91082
(
show subtarget assignments
)
8
cloned
No
CPF_1776
110800219
ABC transporter, permease/ATP-binding pr...
589
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
39.2%
Clostridium perfringens
IDP91083
(
show subtarget assignments
)
8
cloned
No
BA_0528
30260686
ABC transporter, ATP-binding/permease pr...
586
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
58.2%
Bacillus anthracis
IDP91087
(
show subtarget assignments
)
8
expressed
No
BMA_3102
52427493
carbohydrate isomerase, KpsF/GutQ family...
327
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
30.9%
Burkholderia mallei
Energy metabolism: Sugars
IDP91088
(
show subtarget assignments
)
8
cloned
No
BMA_2275
52429282
kdsB
3-deoxy-D-manno-octulosonate cytidylyltr...
263
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3K8D
52.1%
Burkholderia mallei
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP91090
(
show subtarget assignments
)
8
cloned
No
aq_1546
15606685
kpsF
polysialic acid capsule expression prote...
322
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
25.5%
Aquifex aeolicus
IDP91091
(
show subtarget assignments
)
8
cloned
No
APL_0387
126096663
kpsF
arabinose-5-phosphate isomerase [Actinob...
311
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
27%
Actinobacillus pleuropneumoniae
IDP91106
(
show subtarget assignments
)
8
in_pdb
3QFK
Yes
SAOUHSC_00107
88193920
hypothetical protein SAOUHSC_00107 [Stap...
511
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3QFK
99.8%
Staphylococcus aureus
IDP91143
(
show subtarget assignments
)
8
in_pdb
3R2T
Yes
SAOUHSC_00393
88194188
superantigen-like protein [Staphylococcu...
232
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3R2T
100%
Staphylococcus aureus
IDP91163
(
show subtarget assignments
)
8
cloned
No
VC1507
15641516
phospho-2-dehydro-3-deoxyheptonate aldol...
395
potential drug target /
Shikimate pathway enzyme
Community Requests
1GG1
48.9%
Vibrio cholerae
IDP91164
(
show subtarget assignments
)
8
purified
No
VC0695
15640714
phospho-2-dehydro-3-deoxyheptonate aldol...
357
potential drug target /
Shikimate pathway enzyme
Community Requests
1GG1
50.7%
Vibrio cholerae
IDP91167
(
show subtarget assignments
)
8
expressed
No
STM3401
16766690
aroE
shikimate 5-dehydrogenase
272
potential drug target /
Shikimate pathway enzyme
Community Requests
1NYT
84.9%
Salmonella enterica
IDP91168
(
show subtarget assignments
)
8
purified
No
lmo1490
16803530
-
similar to shikimate 5-dehydrogenase (Ar...
273
potential drug target /
Shikimate pathway enzyme
Community Requests
3DON
45.6%
Listeria monocytogenes
IDP91170
(
show subtarget assignments
)
8
cloned
No
lmo2236
16804275
-
similar to oxidoreductase
289
potential drug target /
Shikimate pathway enzyme
Community Requests
3TNL
52.6%
Listeria monocytogenes
IDP91171
(
show subtarget assignments
)
8
expressed
No
CT_370
9087121
RecName: Full=Shikimate biosynthesis pro...
478
potential drug target /
Shikimate pathway enzyme
Community Requests
2EGG
18.2%
Chlamydia trachomatis
IDP91181
(
show subtarget assignments
)
8
cloned
No
CT578
3329020
wall surface anchor family protein [Chla...
487
virulence/pathogenesis /
Targets that are in a network of interactions with CT670 and CT671. These protei...
Community Requests
Chlamydia trachomatis
IDP91182
(
show subtarget assignments
)
8
expressed
No
CT862
15605598
lcrH_2
type III secretion chaperone [Chlamydia ...
198
virulence/pathogenesis /
Targets that are in a network of interactions with CT670 and CT671. These protei...
Community Requests
2VGX
17.2%
Chlamydia trachomatis
IDP91185
(
show subtarget assignments
)
8
cloned
No
AAC46367
2352978
477
virulence/pathogenesis /
FlrC regulates flagellar synthesis in Vibrio cholerae, and my lab has determined...
Community Requests
1NY5
31.9%
Vibrio cholerae
IDP91193
(
show subtarget assignments
)
8
cloned
No
BAS4092
49187090
-
Stage III sporulation protein AF
210
essential/virulence/pathogenesis /
Essential proteins
Community Requests
Bacillus anthracis
IDP91776
(
show subtarget assignments
)
8
in_crystallization_trials
No
ACM47288
222159815
vanXD
D,D-dipeptidase VanXD [Enterococcus faec...
202
drug resistance /
D,D-dipeptidase
Community Requests
1R44
70.3%
Enterococcus faecium
IDP91775
(
show subtarget assignments
)
8
in_crystallization_trials
No
AAL27443
16612080
vanXYE
VanXYE [Enterococcus faecalis]
193
drug resistance /
D,D-dipeptidase/D,D-carboxypeptidase
Community Requests
Enterococcus faecalis
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