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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 16 of 60, showing 100 records out of 5973 total, starting on record 1501
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90758
(
show subtarget assignments
)
8
cloned
No
VC1149
15641162
glutamate decarboxylase, putative [Vibri...
548
Predicted Essential
Community Requests
2OKJ
26.1%
Vibrio cholerae
IDP90761
(
show subtarget assignments
)
8
cloned
No
Cj1061c
15792388
ileS
isoleucyl-tRNA synthetase [Campylobacter...
917
Predicted Essential
Community Requests
1FFY
38.8%
Campylobacter jejuni
IDP90775
(
show subtarget assignments
)
8
cloned
No
YPO0345
16120680
dipZ
thiol:disulfide interchange protein prec...
595
Predicted Essential
Community Requests
1UC7
12.8%
Yersinia pestis
IDP90779
(
show subtarget assignments
)
8
cloned
No
YPO3497
16123643
nusA
transcription elongation factor NusA [Ye...
495
Predicted Essential
Community Requests
1K0R
24.4%
Yersinia pestis
IDP90783
(
show subtarget assignments
)
8
cloned
No
YPO0649
16120974
uppP
undecaprenyl pyrophosphate phosphatase [...
272
Predicted Essential
Community Requests
Yersinia pestis
IDP90786
(
show subtarget assignments
)
8
cloned
No
Cj1385
15792708
katA
catalase [Campylobacter jejuni subsp. je...
474
Predicted Essential
Community Requests
2ISA
57.8%
Campylobacter jejuni
IDP90795
(
show subtarget assignments
)
8
cloned
No
YPO3244
16123403
fadE
acyl-CoA dehydrogenase [Yersinia pestis ...
815
Predicted Essential
Community Requests
2UXW
18.8%
Yersinia pestis
IDP90807
(
show subtarget assignments
)
8
cloned
No
Cj0279
15791649
carB
carbamoyl phosphate synthase large subun...
1089
Predicted Essential
Community Requests
1BXR
55.3%
Campylobacter jejuni
IDP90811
(
show subtarget assignments
)
8
cloned
No
YPO1216
16121507
gyrA
DNA gyrase subunit A [Yersinia pestis CO...
891
Predicted Essential
Community Requests
3NUH
52.9%
Yersinia pestis
IDP90817
(
show subtarget assignments
)
8
cloned
No
VC2431
15642428
DNA topoisomerase IV subunit B [Vibrio c...
626
Predicted Essential
Community Requests
1S16
49.8%
Vibrio cholerae
IDP90826
(
show subtarget assignments
)
8
cloned
No
YPO3305
16123458
alaS
alanyl-tRNA synthetase [Yersinia pestis ...
875
Predicted Essential
Community Requests
3HXU
45%
Yersinia pestis
IDP90831
(
show subtarget assignments
)
8
cloned
No
YPO0552
16120880
mraY
phospho-N-acetylmuramoyl-pentapeptide-tr...
360
Predicted Essential
Community Requests
Yersinia pestis
IDP90838
(
show subtarget assignments
)
8
cloned
No
YPO2053
16122292
aspS
aspartyl-tRNA synthetase [Yersinia pesti...
598
Predicted Essential
Community Requests
1EQR
80.8%
Yersinia pestis
IDP90848
(
show subtarget assignments
)
8
cloned
No
VC0953
15640969
holA
DNA polymerase III subunit delta [Vibrio...
342
Predicted Essential
Community Requests
1JQJ
49.1%
Vibrio cholerae
IDP90853
(
show subtarget assignments
)
8
cloned
No
YPO0647
16120972
putative glycerol-3-phosphate acyltransf...
216
Predicted Essential
Community Requests
Yersinia pestis
IDP90855
(
show subtarget assignments
)
8
cloned
No
VC2461
15642457
rnc
ribonuclease III [Vibrio cholerae O1 bio...
225
Predicted Essential
Community Requests
2A11
43.3%
Vibrio cholerae
IDP90860
(
show subtarget assignments
)
8
cloned
No
YPO1057
16121357
lpxB
lipid-A-disaccharide synthase [Yersinia ...
394
Predicted Essential
Community Requests
Yersinia pestis
IDP90863
(
show subtarget assignments
)
8
cloned
No
YPO3761
16123898
hemG
protoporphyrinogen oxidase [Yersinia pes...
177
Predicted Essential
Community Requests
Yersinia pestis
IDP90866
(
show subtarget assignments
)
8
cloned
No
YPO0671
16120996
parC
DNA topoisomerase IV subunit A [Yersinia...
757
Predicted Essential
Community Requests
1ZVU
78.2%
Yersinia pestis
IDP90869
(
show subtarget assignments
)
8
cloned
No
Cj1250
15792574
purD
phosphoribosylamine--glycine ligase [Cam...
416
Predicted Essential
Community Requests
1VKZ
42.3%
Campylobacter jejuni
IDP90882
(
show subtarget assignments
)
8
cloned
No
VC1491
15641500
dihydroorotate dehydrogenase 2 [Vibrio c...
336
Predicted Essential
Community Requests
1F76
67.9%
Vibrio cholerae
IDP90887
(
show subtarget assignments
)
8
cloned
No
YPO0104
16120451
menA
1,4-dihydroxy-2-naphthoate octaprenyltra...
305
Predicted Essential
Community Requests
Yersinia pestis
IDP90889
(
show subtarget assignments
)
8
cloned
No
VC0664
15640683
lysS
lysyl-tRNA synthetase [Vibrio cholerae O...
512
Predicted Essential
Community Requests
1E1O
58.8%
Vibrio cholerae
IDP90891
(
show subtarget assignments
)
8
cloned
No
YPO3122
16123287
dnaX
DNA polymerase III subunits gamma and ta...
658
Predicted Essential
Community Requests
1JR3
46.7%
Yersinia pestis
IDP90892
(
show subtarget assignments
)
8
cloned
No
YPO1396
16121676
lpxK
tetraacyldisaccharide 4'-kinase [Yersini...
328
Predicted Essential
Community Requests
Yersinia pestis
IDP90896
(
show subtarget assignments
)
8
cloned
No
YPO0477
16120807
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate...
317
Predicted Essential
Community Requests
3F7T
82.7%
Yersinia pestis
IDP90900
(
show subtarget assignments
)
8
cloned
No
YPO3075
16123252
UDP-2,3-diacylglucosamine hydrolase [Yer...
240
Predicted Essential
Community Requests
Yersinia pestis
IDP90904
(
show subtarget assignments
)
8
cloned
No
YPO0311
16120649
ubiA
4-hydroxybenzoate octaprenyltransferase ...
288
Predicted Essential
Community Requests
Yersinia pestis
IDP90929
(
show subtarget assignments
)
8
cloned
No
STM3714
16766999
rfaK
putative hexose transferase [Salmonella ...
381
Predicted Essential
Community Requests
2BIS
21.5%
Salmonella enterica
IDP90930
(
show subtarget assignments
)
8
cloned
No
YPO3384
16123533
mtn
5'-methylthioadenosine/S-adenosylhomocys...
233
Predicted Essential
Community Requests
1JYS
74.7%
Yersinia pestis
IDP90935
(
show subtarget assignments
)
8
cloned
No
YPO3313
16123466
C-terminal region of transketolase [Yers...
314
Predicted Essential
Community Requests
2O1S
28.7%
Yersinia pestis
IDP90936
(
show subtarget assignments
)
8
cloned
No
YPO2016
16122259
hemA
glutamyl-tRNA reductase [Yersinia pestis...
420
Predicted Essential
Community Requests
1GPJ
32.9%
Yersinia pestis
IDP90937
(
show subtarget assignments
)
8
cloned
No
YPO0110
16120456
priA
primosome assembly protein PriA
732
Predicted Essential
Community Requests
2EYQ
9.4%
Yersinia pestis
IDP90938
(
show subtarget assignments
)
8
cloned
No
NMPDR 243277.1.peg.3917
218
Predicted Essential
Community Requests
2JGV
22.5%
Vibrio cholerae
IDP90940
(
show subtarget assignments
)
8
cloned
No
NMPDR 243277.1.peg.3912
278
Predicted Essential
Community Requests
1DD8
61.9%
Vibrio cholerae
IDP90944
(
show subtarget assignments
)
8
cloned
No
STM1121
16764478
ymdF
putative cytoplasmic protein [Salmonella...
55
This is a protein with experimental and computational evidence for being secrete...
Community Requests
Salmonella enterica
IDP90946
(
show subtarget assignments
)
8
cloned
No
BP1878
33592926
bvgA
virulence factors transcription regulato...
209
BvgA is the transcriptional activator for all known virulence genes in the human...
Community Requests
3C3W
31.6%
Bordetella pertussis
IDP90947
(
show subtarget assignments
)
8
cloned
No
SAR0518
49482744
lysS
lysyl-tRNA synthetase [Staphylococcus au...
495
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3A74
72.1%
Staphylococcus aureus
IDP90948
(
show subtarget assignments
)
8
cloned
No
M5005_Spy_1720
71911533
mga
trans-acting positive regulator [Strepto...
529
The multiple gene regulator of the Group A Streptococcus (Mga) is an established...
Community Requests
Streptococcus pyogenes
IDP90956
(
show subtarget assignments
)
8
cloned
No
UTI89_C1558
122423881
Hypothetical protein yciR
661
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3HVB
15.9%
Escherichia coli
IDP90957
(
show subtarget assignments
)
8
cloned
No
PFL_1902
123656875
Sensory box-containing diguanylate cycla...
572
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
18.4%
Pseudomonas fluorescens
IDP90958
(
show subtarget assignments
)
8
cloned
No
UTI89_C1702
122423767
Hypothetical protein
807
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
1V9Y
18%
Escherichia coli
IDP90959
(
show subtarget assignments
)
8
cloned
No
PP2258
81441302
Sensory box protein
562
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
2R6O
20.6%
Pseudomonas putida
IDP90963
(
show subtarget assignments
)
8
cloned
No
VP2446
81727013
C-di-GMP phosphodiesterase A-related pro...
679
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3PJW
15.5%
Vibrio parahaemolyticus
IDP90967
(
show subtarget assignments
)
8
cloned
No
UTI89_C2819
122422922
Hypothetical protein yfgF
747
C-di-GMP is a universal bacterial second messenger regulating cell-surface assoc...
Community Requests
3HVB
14.2%
Escherichia coli
IDP90975
(
show subtarget assignments
)
8
cloned
No
y0011
22123933
hypothetical protein y0011 [Yersinia pes...
229
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
2DI3
21.4%
Yersinia pestis
IDP90976
(
show subtarget assignments
)
8
cloned
No
y0137
22124057
degQ
protease [Yersinia pestis KIM 10]
463
other biological interest /
bifunctional chaperone / protease
Community Requests
4A8A
67.6%
Yersinia pestis
IDP90979
(
show subtarget assignments
)
8
cloned
No
y0636
22124550
hypothetical protein y0636 [Yersinia pes...
158
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
2Y75
24.1%
Yersinia pestis
IDP90980
(
show subtarget assignments
)
8
cloned
No
y0801
22124714
iron-sulfur cluster insertion protein Er...
119
other biological interest /
protein possibly involved in iron-sulfur cluster synthesis
Community Requests
2APN
75.6%
Yersinia pestis
IDP90984
(
show subtarget assignments
)
8
cloned
No
y0931
22124839
hypothetical protein y0931 [Yersinia pes...
281
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3SHO
12.8%
Yersinia pestis
IDP90986
(
show subtarget assignments
)
8
cloned
No
y0974
22124881
rdgC
recombination associated protein [Yersin...
303
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
2OWL
83.2%
Yersinia pestis
IDP90991
(
show subtarget assignments
)
8
cloned
No
y1282
22125182
formate acetyltransferase [Yersinia pest...
150
other biological interest /
stress-response protein replacind PflA in PflA/PflB complex
Community Requests
1CM5
40%
Yersinia pestis
IDP90992
(
show subtarget assignments
)
8
cloned
No
y1333
22125232
DNA-binding transcriptional regulator Is...
185
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3T8R
25.4%
Yersinia pestis
IDP90998
(
show subtarget assignments
)
8
cloned
No
y1724
22125618
hypothetical protein y1724 [Yersinia pes...
448
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP90999
(
show subtarget assignments
)
8
cloned
No
y1744
22125639
hypothetical protein y1744 [Yersinia pes...
95
other biological interest /
-
Community Requests
1X7V
33.7%
Yersinia pestis
IDP91000
(
show subtarget assignments
)
8
cloned
No
y1726
22125620
hypothetical protein y1726 [Yersinia pes...
334
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91010
(
show subtarget assignments
)
8
cloned
No
y2245
22126131
hypothetical protein y2245 [Yersinia pes...
341
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
3ETN
12.3%
Yersinia pestis
IDP91018
(
show subtarget assignments
)
8
cloned
No
y2737
22126615
hypothetical protein y2737 [Yersinia pes...
164
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91021
(
show subtarget assignments
)
8
cloned
No
y2872
22126749
yiuR
putative outer membrane receptor [Yersin...
665
other biological interest /
putative iron-binding TonB-dependent outer membrane receptor
Community Requests
2HDF
38%
Yersinia pestis
IDP91022
(
show subtarget assignments
)
8
cloned
No
y2966
22126843
ompC
outer membrane porin protein C [Yersinia...
374
drug resistance /
outer membrane porin
Community Requests
2IXX
67.9%
Yersinia pestis
IDP91023
(
show subtarget assignments
)
8
cloned
No
y2980
22126857
hypothetical protein y2980 [Yersinia pes...
180
other biological interest /
-
Community Requests
Yersinia pestis
IDP91024
(
show subtarget assignments
)
8
cloned
No
y2983
22126860
outer membrane protein C2 [Yersinia pest...
371
drug resistance /
anion-specific outer membrane porin
Community Requests
3HW9
59.9%
Yersinia pestis
IDP91026
(
show subtarget assignments
)
8
cloned
No
y3142
22127018
flavodoxin [Yersinia pestis KIM 10]
149
other biological interest /
oxidative stress response protein
Community Requests
2HNA
33.6%
Yersinia pestis
IDP91030
(
show subtarget assignments
)
8
cloned
No
y3978
22127848
hypothetical protein y3978 [Yersinia pes...
244
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
Yersinia pestis
IDP91031
(
show subtarget assignments
)
8
cloned
No
y4125
22127993
solute-binding periplasmic protein precu...
284
other biological interest /
highly abundant periplasmic protein with unknown function
Community Requests
1XT8
31%
Yersinia pestis
IDP91032
(
show subtarget assignments
)
8
cloned
No
Y1069
31795399
toxin [Yersinia pestis KIM]
587
virulence/pathogenesis /
survival factor of Y pestis in the flea
Community Requests
1F0I
22.7%
Yersinia pestis
IDP91033
(
show subtarget assignments
)
8
cloned
No
SAR0023
49240405
sasH
putative 5'-nucleotidase [Staphylococcus...
786
virulence/pathogenesis /
An uncharacterized cell surface protein of staph. aureus with an anchor site for...
Community Requests
2Z1A
22.5%
Staphylococcus aureus
IDP91037
(
show subtarget assignments
)
8
cloned
No
SAHV_0560
156978891
sdrD
Ser-Asp rich fibrinogen-binding, bone si...
1385
virulence/pathogenesis /
Sdr family proteins are interesting cell surface proteins in Staphylococcus aure...
Community Requests
3IS1
8.5%
Staphylococcus aureus
IDP91038
(
show subtarget assignments
)
8
cloned
No
SAHV_2481
156980811
hypothetical protein SAHV_2481 [Staphylo...
1115
drug resistance /
SasG is a highly interesting multi-domain protein involved in biofilm formation ...
Community Requests
3TIQ
18.7%
Staphylococcus aureus
IDP91045
(
show subtarget assignments
)
8
cloned
No
ECH0010
15799700
hypothetical protein Z0021 [Escherichia ...
108
virulence/pathogenesis /
Hypothetical protein Z0021 is involved in regulation of swimming motility in E. ...
Community Requests
Escherichia coli
IDP91055
(
show subtarget assignments
)
8
cloned
No
NP_818933
29611985
nonstructural protein nsP1 [Western equi...
533
potential drug target /
A structure of the nsP1 from Western Equine encephalitis virus (WEEV) nonstructu...
Community Requests
Western equine
IDP91057
(
show subtarget assignments
)
8
cloned
No
USA300HOU_2035
161510252
agrA
accessory gene regulator protein A [Stap...
238
virulence/pathogenesis /
The target is a drug target for anti-virulence therapy in infections of Methicil...
Community Requests
3BS1
42.9%
Staphylococcus aureus
IDP91062
(
show subtarget assignments
)
8
cloned
No
YPO0195
16120534
fkpA
peptidyl-prolyl cis-trans isomerase
266
virulence/pathogenesis /
Gene encodes a Mip orthologue which has shown to be important for virulence in v...
Community Requests
1Q6U
70.3%
Yersinia pestis
IDP91064
(
show subtarget assignments
)
1
cloned
No
y2422
21959284
144
other biological interest /
Identified in a mutant screen
Community Requests
Yersinia pestis
IDP91068
(
show subtarget assignments
)
8
cloned
No
VF_A0424
59713607
msbA
lipid transporter ATP-binding/permease p...
582
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5X
75.1%
Vibrio fischeri
IDP91069
(
show subtarget assignments
)
8
cloned
No
SP_1357
15901211
ABC transporter, ATP-binding/permease pr...
596
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
37.1%
Streptococcus pneumoniae
IDP91070
(
show subtarget assignments
)
8
cloned
No
RP205
15604078
multidrug resistance transporter ATM1 [R...
609
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
32%
Rickettsia prowazekii
IDP91071
(
show subtarget assignments
)
8
cloned
No
NGO2165
59719354
putative ABC transporter, ATP-binding pr...
622
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5Y
34.2%
Neisseria gonorrhoeae
IDP91072
(
show subtarget assignments
)
8
cloned
No
YPO2588
16122801
-
putative ABC transport protein
631
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
32.2%
Yersinia pestis
IDP91073
(
show subtarget assignments
)
8
cloned
No
YPO1395
16121675
msbA
probable transport ATP-binding protein
582
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5W
85.2%
Yersinia pestis
IDP91074
(
show subtarget assignments
)
8
cloned
No
MSMEG_5659
118469658
ABC transporter, ATP-binding protein [My...
610
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
32.1%
Mycobacterium smegmatis
IDP91075
(
show subtarget assignments
)
8
cloned
No
jhp0343
15611411
msbA
multi-drug resistance protein [Helicobac...
551
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5W
31.4%
Helicobacter pylori
IDP91076
(
show subtarget assignments
)
8
cloned
No
CGSHiII_09046
145639651
fused lipid transporter subunits of ABC ...
587
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5W
65.9%
Haemophilus influenzae
IDP91077
(
show subtarget assignments
)
8
cloned
No
FTT_0109
56707283
msbA
Lipid A transport protein, ABC transport...
609
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5W
41.2%
Francisella tularensis
IDP91078
(
show subtarget assignments
)
8
cloned
No
CBU_0856
29541449
ABC transporter, ATP-binding/permease pr...
596
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5X
42.3%
Coxiella burnetii
IDP91079
(
show subtarget assignments
)
8
cloned
No
BMA0204
53725011
ABC transporter, ATP-binding/permease pr...
623
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
4AA3
32.8%
Burkholderia mallei
IDP91080
(
show subtarget assignments
)
8
cloned
No
Cj0803
6968244
msbA
lipid export ABC transport protein
580
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
31.6%
Campylobacter jejuni
IDP91081
(
show subtarget assignments
)
8
cloned
No
CD2817
126700433
ABC transporter, ATP-binding/permease pr...
596
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
39.4%
Clostridium difficile
IDP91082
(
show subtarget assignments
)
8
cloned
No
CPF_1776
110800219
ABC transporter, permease/ATP-binding pr...
589
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
39.2%
Clostridium perfringens
IDP91083
(
show subtarget assignments
)
8
cloned
No
BA_0528
30260686
ABC transporter, ATP-binding/permease pr...
586
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
58.2%
Bacillus anthracis
IDP91084
(
show subtarget assignments
)
8
cloned
No
BA_2444
30262443
ABC transporter, ATP-binding/permease pr...
598
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
44.5%
Bacillus anthracis
IDP91088
(
show subtarget assignments
)
8
cloned
No
BMA_2275
52429282
kdsB
3-deoxy-D-manno-octulosonate cytidylyltr...
263
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3K8D
52.1%
Burkholderia mallei
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP91090
(
show subtarget assignments
)
8
cloned
No
aq_1546
15606685
kpsF
polysialic acid capsule expression prote...
322
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
25.5%
Aquifex aeolicus
IDP91091
(
show subtarget assignments
)
8
cloned
No
APL_0387
126096663
kpsF
arabinose-5-phosphate isomerase [Actinob...
311
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
2XHZ
27%
Actinobacillus pleuropneumoniae
IDP91094
(
show subtarget assignments
)
8
cloned
No
APL_0085
126096365
kdsB
3-deoxy-manno-octulosonate cytidylyltran...
250
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
1VH3
70.6%
Actinobacillus pleuropneumoniae
IDP91163
(
show subtarget assignments
)
8
cloned
No
VC1507
15641516
phospho-2-dehydro-3-deoxyheptonate aldol...
395
potential drug target /
Shikimate pathway enzyme
Community Requests
1GG1
48.9%
Vibrio cholerae
IDP91165
(
show subtarget assignments
)
8
cloned
No
VC_2116
12229712
aroC
RecName: Full=Chorismate synthase; AltNa...
361
potential drug target /
Shikimate pathway enzyme
Community Requests
1R52
46.1%
Vibrio cholerae
IDP91170
(
show subtarget assignments
)
8
cloned
No
lmo2236
16804275
-
similar to oxidoreductase
289
potential drug target /
Shikimate pathway enzyme
Community Requests
3TNL
52.6%
Listeria monocytogenes
IDP91180
(
show subtarget assignments
)
8
cloned
No
CT576
15605305
lcrH_1
low calcium response protein H [Chlamydi...
232
virulence/pathogenesis /
Targets that are in a network of interactions with CT670 and CT671. These protei...
Community Requests
2VGX
19%
Chlamydia trachomatis
IDP91181
(
show subtarget assignments
)
8
cloned
No
CT578
3329020
wall surface anchor family protein [Chla...
487
virulence/pathogenesis /
Targets that are in a network of interactions with CT670 and CT671. These protei...
Community Requests
Chlamydia trachomatis
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Filter Columns:
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