Center for Structural Genomics of Infectious Diseases


CSGID ID	Priority	stage	Screening	Locus Tag	NCBI GI	Gene Name	Common Name	Sequence Length	Justification	Selection Phase	Homolog PDB ID	Homolog Sequence Identity	Target Organism	TIGR Main Role	TIGR Subrole	Request Person
IDP04467 (show subtarget assignments)	1	soluble	No	YPO2174	218929273		putative nucleotide sugar dehydrogenase ...	448	virulence factor; putative drug target function;	Phase 4: April 2009	2Y0E	57.9%	Yersinia pestis	Unclassified	Role category not yet assigned

IDP02101 (show subtarget assignments)	1	expressed	No	STM3638	16766924	lpfC	long polar fimbrial outer membrane usher...	842	Conserved; Drug target functions	Phase 3: June 2008	3RFZ	44.8%	Salmonella enterica	Unclassified	Role category not yet assigned

IDP04399 (show subtarget assignments)	1	cloned	No	YPO3613	218930623		putative Rhs accessory genetic element [...	732	virulence factor; putative drug target function;	Phase 4: April 2009	2P5Z	15.8%	Yersinia pestis	Unclassified	Role category not yet assigned

IDP02419 (show subtarget assignments)	1	purified	No	FTT1447c	56708489	manB	phosphomannomutase [Francisella tularens...	494	Conserved; Drug target functions; Drug target motif	Phase 3: June 2008	2F7L	25.7%	Francisella tularensis	Unclassified	Role category not yet assigned

IDP02397 (show subtarget assignments)	1	purified	No	FTT1326	56708383	udp	uridine phosphorylase [Francisella tular...	267	Drug Target	Phase 3: June 2008	3O6V	43.1%	Francisella tularensis	Unclassified	Role category not yet assigned

IDP02408 (show subtarget assignments)	1	in_crystallization_trials	No	YPO1418	16121698		23S rRNA m(2)G2445 methyltransferase [Ye...	706	Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...	Phase 3: June 2008	3V8V	74.8%	Yersinia pestis	Unclassified	Role category not yet assigned

IDP02817 (show subtarget assignments)	1	cloned	No	lmo2185	16804224		hypothetical protein lmo2185 [Listeria m...	569	Known virulence-Intracellular Survival; Predicted virulence-Iron Scavenging Mech...	Phase 3: June 2008	2O6P	8.4%	Listeria monocytogenes	Unclassified	Role category not yet assigned

IDP02352 (show subtarget assignments)	1	cloned	No	FTT1334c	56708390		hypothetical protein FTT1334c [Francisel...	169	Drug Target	Phase 3: June 2008			Francisella tularensis	Unclassified	Role category not yet assigned

IDP02345 (show subtarget assignments)	1	in_crystallization_trials	No	FTT1220	56708282		5-formyltetrahydroformate cycloligase fa...	182	Drug Target	Phase 3: June 2008	2JCB	28.6%	Francisella tularensis	Unclassified	Role category not yet assigned

IDP02774 (show subtarget assignments)	1	soluble	No	FTT0392c	56707541		hypothetical protein FTT0392c [Francisel...	109	Drug Target	Phase 3: June 2008			Francisella tularensis	Unclassified	Role category not yet assigned

IDP00074 (show subtarget assignments)	0	work_stopped	No	NT01ST3685	16421504	pyrG	CTP synthetase	545	Essential	Phase 1: October 2007	1S1M	95%	Salmonella enterica	Unclassified	Role category not yet assigned

IDP00073 (show subtarget assignments)	1	crystallized	No	NT01ST3324	16421221	rimM	16S rRNA processing protein	182	Essential	Phase 1: October 2007	3H9N	63.2%	Salmonella enterica	Unclassified	Role category not yet assigned

IDP00325 (show subtarget assignments)	1	crystallized	No	Cj1530	15792838	coaE	dephospho-CoA kinase	201	Drug Target Function	Phase 2: March 2008	2IF2	32.8%	Campylobacter jejuni	Unclassified	Unclassified

IDP02308 (show subtarget assignments)	1	expressed	No	FTT1400c	56708448		hypothetical protein FTT1400c [Francisel...	128	Drug Target	Phase 3: June 2008			Francisella tularensis	Unclassified	Role category not yet assigned

IDP00324 (show subtarget assignments)	1	cloned	No	Cj1366c	15792689	glmS	D-fructose-6-phosphate amidotransferase ...	598	Drug Target Function	Phase 2: March 2008	1JXA	41.3%	Campylobacter jejuni	Unclassified	Unclassified

IDP02281 (show subtarget assignments)	1	cloned	No	YPO1305	16121587	psaC	outer membrane usher protein PsaC precur...	837	Conserved; CD; Involved in virulence; Drug target functions	Phase 3: June 2008	3RFZ	36.5%	Yersinia pestis	Unclassified	Role category not yet assigned

IDP02256 (show subtarget assignments)	1	purified	No	YPO1262	16121548		nucleoid-associated protein NdpA [Yersin...	334	Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...	Phase 3: June 2008			Yersinia pestis	Unclassified	Role category not yet assigned

IDP02236 (show subtarget assignments)	1	cloned	No	FTT1108	56708186		rRNA methyltransferase [Francisella tula...	250	Drug Target	Phase 3: June 2008	1IPA	29.3%	Francisella tularensis	Unclassified	Role category not yet assigned

IDP02705 (show subtarget assignments)	1	cloned	No	lmo0202	16802248	hly	listeriolysin O precursor [Listeria mono...	529	Known virulence-Toxin; Predicted virulence-Pathogenicity islands; PMID:11901162	Phase 3: June 2008	3HVN	41%	Listeria monocytogenes	Unclassified	Role category not yet assigned

IDP02068 (show subtarget assignments)	1	crystallized	No	YPO3194	16123356	ahpC	putative alkyl hydroperoxide reductase s...	200	Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...	Phase 3: June 2008	1ZOF	59%	Yersinia pestis	Unclassified	Role category not yet assigned

IDP02228 (show subtarget assignments)	1	cloned	No	FTT1240c	56708302		hypothetical protein FTT1240c [Francisel...	182	Drug Target	Phase 3: June 2008	2P0T	32.4%	Francisella tularensis	Unclassified	Role category not yet assigned

IDP02690 (show subtarget assignments)	1	cloned	No	FTT0954c	56708048		hypothetical protein FTT0954c [Francisel...	106	Drug Target	Phase 3: June 2008	1Y2I	36.8%	Francisella tularensis	Unclassified	Role category not yet assigned

IDP00277 (show subtarget assignments)	1	cloned	No	AAA99437_5-114	323469	N/A	Capsid protein (C)	110	Encapsidation of genomic RNA	Phase 3: June 2008	1R6R	57.3%	Dengue virus	Unclassified	N/A

IDP05357 (show subtarget assignments)	1	soluble	No	BA_0382	30253917		putative ABC transporter, substrate-bind...	332	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3IX1	25.9%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05366 (show subtarget assignments)	1	soluble	No	BA_2255	30256899		putative substrate-binding family protei...	320	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3MWF	33.4%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05370 (show subtarget assignments)	1	cloned	No	BA_5220	30259701		putative ABC transporter, substrate-bind...	270	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	4EF1	50.7%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05164 (show subtarget assignments)	1	purified	No	BA_1735	30256021		putative ABC transporter, substrate-bind...	341	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	4EDP	26.7%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05139 (show subtarget assignments)	1	soluble	No	BAS0353	49183381	-	amino acid ABC transporter, solute bindi...	264	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3TQL	30.3%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05127 (show subtarget assignments)	1	soluble	No	BA_4652	30259150		putative substrate-binding family protei...	314	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3HXP	29.6%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05564 (show subtarget assignments)	1	cloned	No	lmo2431	16804469	-	hypothetical protein lmo2431 [Listeria m...	323	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2Q8P	24.5%	Listeria monocytogenes	Transport and binding proteins: Unknown substrate

IDP05119 (show subtarget assignments)	1	soluble	No	CD2989	126700610		ABC transporter, substrate-binding prote...	319	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2X7P	23.5%	Clostridium difficile	Transport and binding proteins: Unknown substrate

IDP05328 (show subtarget assignments)	1	soluble	No	lmo2591	16804629	-	GW repeat-containing surface protein [Li...	508	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1M9S	17.7%	Listeria monocytogenes	Transport and binding proteins: Unknown substrate

IDP05096 (show subtarget assignments)	1	cloned	No	CD0015	126697581		putative cytosine/adenosine deaminase [C...	155	essential/virulence/pathogenesis / Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...	Phase 5: 2010	1WWR	48.1%	Clostridium difficile	Transport and binding proteins: Unknown substrate

IDP05078 (show subtarget assignments)	1	soluble	No	lmo1340	16803380	-	hypothetical protein lmo1340 [Listeria m...	363	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010			Listeria monocytogenes	Transport and binding proteins: Unknown substrate

IDP05364 (show subtarget assignments)	1	soluble	No	BA_2881	30257478		bacterial extracellular solute-binding p...	578	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3M8U	19.2%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05631 (show subtarget assignments)	1	crystallized	No	CD1979	126699588		ABC transporter, substrate-binding prote...	337	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3IX1	26.4%	Clostridium difficile	Transport and binding proteins: Unknown substrate

IDP05181 (show subtarget assignments)	1	soluble	No	BA_4729	30259221		bacterial extracellular solute-binding p...	521	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1UQW	30.3%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05760 (show subtarget assignments)	1	purified	No	lmo1959	16803998	-	hypothetical protein lmo1959 [Listeria m...	303	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3HXP	37%	Listeria monocytogenes	Transport and binding proteins: Unknown substrate

IDP05694 (show subtarget assignments)	1	soluble	No	lmo2007	16804046	-	hypothetical protein lmo2007 [Listeria m...	485	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3OMB	21.3%	Listeria monocytogenes	Transport and binding proteins: Unknown substrate

IDP05415 (show subtarget assignments)	1	soluble	No	BA_5219	30259700		putative ABC transporter, substrate-bind...	268	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	4EF1	49.6%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05245 (show subtarget assignments)	1	soluble	No	lmo2349	16804387	-	hypothetical protein lmo2349 [Listeria m...	269	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2O1M	71%	Listeria monocytogenes	Transport and binding proteins: Unknown substrate

IDP05708 (show subtarget assignments)	1	soluble	No	lmo2839	16804876	-	hypothetical protein lmo2839 [Listeria m...	430	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3QUF	24.4%	Listeria monocytogenes	Transport and binding proteins: Unknown substrate

IDP05197 (show subtarget assignments)	1	cloned	No	CD1131	126698725		putative solute-binding lipoprotein [Clo...	556	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3RQT	19.8%	Clostridium difficile	Transport and binding proteins: Unknown substrate

IDP05714 (show subtarget assignments)	1	purified	No	BA_0175	30253683		putative ABC transporter, substrate-bind...	270	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3K2D	37.8%	Bacillus anthracis	Transport and binding proteins: Unknown substrate

IDP05664 (show subtarget assignments)	1	purified	No	lmo0341	16802386	-	hypothetical protein lmo0341 [Listeria m...	110	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2IP6	30%	Listeria monocytogenes	Transport and binding proteins: Other

IDP05138 (show subtarget assignments)	1	cloned	No	CD2874	126700490		putative drug/sodium antiporter [Clostri...	446	virulence/pathogenesis / Targets associated with virulence and/or pathogenesis	Phase 5: 2010			Clostridium difficile	Transport and binding proteins: Other

IDP05294 (show subtarget assignments)	1	cloned	No	CD1418	126699021		putative drug/sodium antiporter [Clostri...	451	virulence/pathogenesis / Targets associated with virulence and/or pathogenesis	Phase 5: 2010	3MKT	20.6%	Clostridium difficile	Transport and binding proteins: Other

IDP05398 (show subtarget assignments)	1	soluble	No	BA_3750	30258269		putative phosphonate ABC transporter, ph...	312	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3N5L	21.8%	Bacillus anthracis	Transport and binding proteins: Other

IDP05738 (show subtarget assignments)	1	cloned	No	CD2090	126699707		putative xanthine/uracile permease [Clos...	453	essential/virulence/pathogenesis / Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...	Phase 5: 2010	3QE7	28%	Clostridium difficile	Transport and binding proteins: Nucleosides, purines and pyrimidines

IDP05678 (show subtarget assignments)	1	in_crystallization_trials	No	lmo1041	16803081	-	hypothetical protein lmo1041 [Listeria m...	256	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1AMF	30.9%	Listeria monocytogenes	Transport and binding proteins: Cations and iron carrying compounds

IDP05715 (show subtarget assignments)	1	purified	No	BA_0351	30253889		iron compound ABC transporter, iron comp...	305	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3HXP	36.1%	Bacillus anthracis	Transport and binding proteins: Cations and iron carrying compounds

IDP05050 (show subtarget assignments)	1	purified	No	BA_5330	30259806		iron compound ABC transporter, iron comp...	333	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3GFV	26.4%	Bacillus anthracis	Transport and binding proteins: Cations and iron carrying compounds

IDP05404 (show subtarget assignments)	1	soluble	No	BA_5628	30260080		iron compound ABC transporter, iron comp...	314	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3HXP	29.6%	Bacillus anthracis	Transport and binding proteins: Cations and iron carrying compounds

IDP05227 (show subtarget assignments)	1	soluble	No	lmo0541	16802584	-	hypothetical protein lmo0541 [Listeria m...	306	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3EIW	28.1%	Listeria monocytogenes	Transport and binding proteins: Cations and iron carrying compounds

IDP05369 (show subtarget assignments)	1	soluble	No	BA_4597	30259097		iron compound ABC transporter, iron comp...	315	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2PHZ	27%	Bacillus anthracis	Transport and binding proteins: Cations and iron carrying compounds

IDP05674 (show subtarget assignments)	1	soluble	No	lmo0859	16802900	-	hypothetical protein lmo0859 [Listeria m...	439	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3QUF	23.7%	Listeria monocytogenes	Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05349 (show subtarget assignments)	1	cloned	No	CD2487	126700104		PTS system, IIB component [Clostridium d...	105	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2KYR	67.6%	Clostridium difficile	Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05311 (show subtarget assignments)	1	cloned	No	CD3014	126700634		PTS system, IIB component [Clostridium d...	106	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2R4Q	45.3%	Clostridium difficile	Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05707 (show subtarget assignments)	1	expressed	No	lmo2762	16804799	-	hypothetical protein lmo2762 [Listeria m...	100	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1H9C	44%	Listeria monocytogenes	Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05591 (show subtarget assignments)	1	purified	No	BA_2975	30257565		putative sugar ABC transporter, sugar-bi...	347	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1TJY	57.1%	Bacillus anthracis	Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05433 (show subtarget assignments)	1	soluble	No	lmo1730	16803770	-	hypothetical protein lmo1730 [Listeria m...	414	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3UOR	33.6%	Listeria monocytogenes	Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05406 (show subtarget assignments)	1	in_crystallization_trials	No	BA_0669	30254269	rbsB	ribose ABC transporter, ribose-binding p...	308	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2IOY	51.9%	Bacillus anthracis	Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05042 (show subtarget assignments)	1	soluble	No	BA_2921	30257513		putative sulfonate ABC transporter, sulf...	328	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2X26	28%	Bacillus anthracis	Transport and binding proteins: Anions

IDP05504 (show subtarget assignments)	1	purified	No	CD0869	126698446	modA	putative molybdenum ABC transporter,subs...	270	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1AMF	31.9%	Clostridium difficile	Transport and binding proteins: Anions

IDP05439 (show subtarget assignments)	1	soluble	No	lmo2499	16804537	-	hypothetical protein lmo2499 [Listeria m...	302	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	4ECF	53.6%	Listeria monocytogenes	Transport and binding proteins: Anions

IDP05158 (show subtarget assignments)	1	cloned	No	BA_1197	30255150		oligopeptide ABC transporter, oligopepti...	532	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3O9P	29.7%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05157 (show subtarget assignments)	1	soluble	No	BA_1191	30254904		oligopeptide ABC transporter, oligopepti...	543	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1B05	29.3%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05153 (show subtarget assignments)	1	soluble	No	BA_0656	30254258		oligopeptide ABC transporter, oligopepti...	593	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3DRF	32.4%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05150 (show subtarget assignments)	1	in_crystallization_trials	No	BA_0195	30253702		putative oligopeptide ABC transporter, o...	546	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1B05	29.9%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05149 (show subtarget assignments)	1	purified	No	BA_0194	30253701		putative oligopeptide ABC transporter, o...	546	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1B05	30.2%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05673 (show subtarget assignments)	1	soluble	No	lmo0810	16802852	-	hypothetical protein lmo0810 [Listeria m...	357	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	4EQB	54.6%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05135 (show subtarget assignments)	1	soluble	No	CD0855	126698435	oppA	oligopeptide ABC transporter, substrate-...	522	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1XOC	33.1%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05561 (show subtarget assignments)	1	cloned	No	lmo2026	16804065	-	peptidoglycan binding protein [Listeria ...	626	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1M0Z	11%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05549 (show subtarget assignments)	1	soluble	No	lmo0549	16802592	-	hypothetical protein lmo0549 [Listeria m...	673	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1M9S	14.6%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05100 (show subtarget assignments)	1	soluble	No	CD0876	126698453		ABC transporter, substrate-binding lipop...	345	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3LFT	32.2%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05699 (show subtarget assignments)	1	cloned	No	lmo2396	16804434	-	hypothetical protein lmo2396 [Listeria m...	940	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1O6S	10.9%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05081 (show subtarget assignments)	1	expressed	No	lmo2027	16804066	-	putative cell surface protein, internali...	367	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2Y5Q	23.2%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05074 (show subtarget assignments)	1	cloned	No	lmo0135	16802183	-	hypothetical protein lmo0135 [Listeria m...	524	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1XOC	32.4%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05634 (show subtarget assignments)	1	soluble	No	CD2174	126699790		amino-acid ABC transporter,substrate-bin...	270	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2IEE	29.3%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05633 (show subtarget assignments)	1	purified	No	CD2177	126699793		amino-acid ABC transporter,substrate-bin...	267	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2IEE	32.6%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05525 (show subtarget assignments)	1	soluble	No	CD2550	126700167		putative sugar transporter, substrate-bi...	430	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1EU8	25.8%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05035 (show subtarget assignments)	1	in_crystallization_trials	No	BA_1300	30255245	potD	spermidine/putrescine ABC transporter, s...	345	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1POT	35.7%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05031 (show subtarget assignments)	1	soluble	No	BA_0908	30254654		oligopeptide ABC transporter, oligopepti...	528	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1XOC	30.7%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05027 (show subtarget assignments)	1	purified	No	BA_0231	30253731		putative oligopeptide ABC transporter, o...	555	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3DRF	27.3%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05020 (show subtarget assignments)	1	soluble	No	CD1027	126698611	potD	spermidine/putrescine ABC transporter,su...	350	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	4EQB	39.1%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05622 (show subtarget assignments)	1	soluble	No	CD0999	126698583		ABC transporter, substrate-binding lipop...	331	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3HN0	24.2%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05021 (show subtarget assignments)	1	soluble	No	CD1139	126698733	rnfG	electron transport complex protein [Clos...	189	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010			Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05319 (show subtarget assignments)	1	soluble	No	BA_2848	30257448		putative oligopeptide ABC transporter, o...	540	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2Z23	29.3%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05180 (show subtarget assignments)	1	soluble	No	BA_3644	30258169		putative oligopeptide ABC transporter, o...	568	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3TCF	29.6%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05630 (show subtarget assignments)	1	soluble	No	CD1774	126699383		amino acid ABC transporter, substrate-bi...	267	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3HV1	36%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP05599 (show subtarget assignments)	1	purified	No	BA_3642	30258168		putative oligopeptide ABC transporter, o...	568	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1B05	28.9%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05711 (show subtarget assignments)	1	soluble	No	BAS1732	49184745	-	oligopeptide ABC transporter, solute bin...	519	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1B05	28.5%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05446 (show subtarget assignments)	1	soluble	No	lmo1738	16803778	-	hypothetical protein lmo1738 [Listeria m...	271	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3HV1	49.4%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05600 (show subtarget assignments)	1	soluble	No	BA_3645	30258170		putative oligopeptide ABC transporter, o...	562	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1B05	29.5%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05431 (show subtarget assignments)	1	cloned	No	lmo1224	16803264	-	hypothetical protein lmo1224 [Listeria m...	1136	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010			Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05579 (show subtarget assignments)	1	soluble	No	BA_0855	30254440		amino acid ABC transporter, amino acid-b...	265	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2YLN	40.8%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05270 (show subtarget assignments)	1	soluble	No	lmo1016	16803056	gbuC	hypothetical protein lmo1016 [Listeria m...	249	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	2B4L	51%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05713 (show subtarget assignments)	1	cloned	No	BA_0189	30253696		oligopeptide ABC transporter, oligopepti...	536	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	1B05	31.2%	Bacillus anthracis	Transport and binding proteins: Amino acids, peptides and amines

IDP05685 (show subtarget assignments)	1	soluble	No	lmo1426	16803466	opuCC	hypothetical protein lmo1426 [Listeria m...	308	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3PPN	57.1%	Listeria monocytogenes	Transport and binding proteins: Amino acids, peptides and amines

IDP05207 (show subtarget assignments)	1	cloned	No	CD2365	126699980		putative sulfonate ABC transporter,solut...	363	associated with virulence and/or pathogenesis; vaccine candidate	Phase 5: 2010	3QSL	20.4%	Clostridium difficile	Transport and binding proteins: Amino acids, peptides and amines

IDP04467
(show subtarget assignments)

1

soluble

No

YPO2174

218929273

putative nucleotide sugar dehydrogenase ...

448

virulence factor; putative drug target function;

Phase 4: April 2009

2Y0E

57.9%

Yersinia pestis

Unclassified

Role category not yet assigned

IDP02101
(show subtarget assignments)

1

expressed

No

STM3638

16766924

lpfC

long polar fimbrial outer membrane usher...

842

Conserved; Drug target functions

Phase 3: June 2008

3RFZ

44.8%

Salmonella enterica

Unclassified

Role category not yet assigned

IDP04399
(show subtarget assignments)

1

cloned

No

YPO3613

218930623

putative Rhs accessory genetic element [...

732

virulence factor; putative drug target function;

Phase 4: April 2009

2P5Z

15.8%

Yersinia pestis

Unclassified

Role category not yet assigned

IDP02419
(show subtarget assignments)

1

purified

No

FTT1447c

56708489

manB

phosphomannomutase [Francisella tularens...

494

Conserved; Drug target functions; Drug target motif

Phase 3: June 2008

2F7L

25.7%

Francisella tularensis

Unclassified

Role category not yet assigned

IDP02397
(show subtarget assignments)

1

purified

No

FTT1326

56708383

udp

uridine phosphorylase [Francisella tular...

267

Drug Target

Phase 3: June 2008

3O6V

43.1%

Francisella tularensis

Unclassified

Role category not yet assigned

IDP02408
(show subtarget assignments)

1

in_crystallization_trials

No

YPO1418

16121698

23S rRNA m(2)G2445 methyltransferase [Ye...

706

Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...

Phase 3: June 2008

3V8V

74.8%

Yersinia pestis

Unclassified

Role category not yet assigned

IDP02817
(show subtarget assignments)

1

cloned

No

lmo2185

16804224

hypothetical protein lmo2185 [Listeria m...

569

Known virulence-Intracellular Survival; Predicted virulence-Iron Scavenging Mech...

Phase 3: June 2008

2O6P

8.4%

Listeria monocytogenes

Unclassified

Role category not yet assigned

IDP02352
(show subtarget assignments)

1

cloned

No

FTT1334c

56708390

hypothetical protein FTT1334c [Francisel...

169

Drug Target

Phase 3: June 2008

Francisella tularensis

Unclassified

Role category not yet assigned

IDP02345
(show subtarget assignments)

1

in_crystallization_trials

No

FTT1220

56708282

5-formyltetrahydroformate cycloligase fa...

182

Drug Target

Phase 3: June 2008

2JCB

28.6%

Francisella tularensis

Unclassified

Role category not yet assigned

IDP02774
(show subtarget assignments)

1

soluble

No

FTT0392c

56707541

hypothetical protein FTT0392c [Francisel...

109

Drug Target

Phase 3: June 2008

Francisella tularensis

Unclassified

Role category not yet assigned

IDP00074
(show subtarget assignments)

0

work_stopped

No

NT01ST3685

16421504

pyrG

CTP synthetase

545

Essential

Phase 1: October 2007

1S1M

95%

Salmonella enterica

Unclassified

Role category not yet assigned

IDP00073
(show subtarget assignments)

1

crystallized

No

NT01ST3324

16421221

rimM

16S rRNA processing protein

182

Essential

Phase 1: October 2007

3H9N

63.2%

Salmonella enterica

Unclassified

Role category not yet assigned

IDP00325
(show subtarget assignments)

1

crystallized

No

Cj1530

15792838

coaE

dephospho-CoA kinase

201

Drug Target Function

Phase 2: March 2008

2IF2

32.8%

Campylobacter jejuni

Unclassified

IDP02308
(show subtarget assignments)

1

expressed

No

FTT1400c

56708448

hypothetical protein FTT1400c [Francisel...

128

Drug Target

Phase 3: June 2008

Francisella tularensis

Unclassified

Role category not yet assigned

IDP00324
(show subtarget assignments)

1

cloned

No

Cj1366c

15792689

glmS

D-fructose-6-phosphate amidotransferase ...

598

Drug Target Function

Phase 2: March 2008

1JXA

41.3%

Campylobacter jejuni

Unclassified

IDP02281
(show subtarget assignments)

1

cloned

No

YPO1305

16121587

psaC

outer membrane usher protein PsaC precur...

837

Conserved; CD; Involved in virulence; Drug target functions

Phase 3: June 2008

3RFZ

36.5%

Yersinia pestis

Unclassified

Role category not yet assigned

IDP02256
(show subtarget assignments)

1

purified

No

YPO1262

16121548

nucleoid-associated protein NdpA [Yersin...

334

Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...

Phase 3: June 2008

Yersinia pestis

Unclassified

Role category not yet assigned

IDP02236
(show subtarget assignments)

1

cloned

No

FTT1108

56708186

rRNA methyltransferase [Francisella tula...

250

Drug Target

Phase 3: June 2008

1IPA

29.3%

Francisella tularensis

Unclassified

Role category not yet assigned

IDP02705
(show subtarget assignments)

1

cloned

No

lmo0202

16802248

hly

listeriolysin O precursor [Listeria mono...

529

Known virulence-Toxin; Predicted virulence-Pathogenicity islands; PMID:11901162

Phase 3: June 2008

3HVN

41%

Listeria monocytogenes

Unclassified

Role category not yet assigned

IDP02068
(show subtarget assignments)

1

crystallized

No

YPO3194

16123356

ahpC

putative alkyl hydroperoxide reductase s...

200

Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...

Phase 3: June 2008

1ZOF

59%

Yersinia pestis

Unclassified

Role category not yet assigned

IDP02228
(show subtarget assignments)

1

cloned

No

FTT1240c

56708302

hypothetical protein FTT1240c [Francisel...

182

Drug Target

Phase 3: June 2008

2P0T

32.4%

Francisella tularensis

Unclassified

Role category not yet assigned

IDP02690
(show subtarget assignments)

1

cloned

No

FTT0954c

56708048

hypothetical protein FTT0954c [Francisel...

106

Drug Target

Phase 3: June 2008

1Y2I

36.8%

Francisella tularensis

Unclassified

Role category not yet assigned

IDP00277
(show subtarget assignments)

1

cloned

No

AAA99437_5-114

323469

N/A

Capsid protein (C)

110

Encapsidation of genomic RNA

Phase 3: June 2008

1R6R

57.3%

Dengue virus

Unclassified

N/A

IDP05357
(show subtarget assignments)

1

soluble

No

BA_0382

30253917

putative ABC transporter, substrate-bind...

332

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3IX1

25.9%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05366
(show subtarget assignments)

1

soluble

No

BA_2255

30256899

putative substrate-binding family protei...

320

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3MWF

33.4%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05370
(show subtarget assignments)

1

cloned

No

BA_5220

30259701

putative ABC transporter, substrate-bind...

270

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

4EF1

50.7%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05164
(show subtarget assignments)

1

purified

No

BA_1735

30256021

putative ABC transporter, substrate-bind...

341

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

4EDP

26.7%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05139
(show subtarget assignments)

1

soluble

No

BAS0353

49183381

-

amino acid ABC transporter, solute bindi...

264

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3TQL

30.3%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05127
(show subtarget assignments)

1

soluble

No

BA_4652

30259150

putative substrate-binding family protei...

314

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3HXP

29.6%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05564
(show subtarget assignments)

1

cloned

No

lmo2431

16804469

-

hypothetical protein lmo2431 [Listeria m...

323

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2Q8P

24.5%

Listeria monocytogenes

Transport and binding proteins: Unknown substrate

IDP05119
(show subtarget assignments)

1

soluble

No

CD2989

126700610

ABC transporter, substrate-binding prote...

319

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2X7P

23.5%

Clostridium difficile

Transport and binding proteins: Unknown substrate

IDP05328
(show subtarget assignments)

1

soluble

No

lmo2591

16804629

-

GW repeat-containing surface protein [Li...

508

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1M9S

17.7%

Listeria monocytogenes

Transport and binding proteins: Unknown substrate

IDP05096
(show subtarget assignments)

1

cloned

No

CD0015

126697581

putative cytosine/adenosine deaminase [C...

155

essential/virulence/pathogenesis / Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...

Phase 5: 2010

1WWR

48.1%

Clostridium difficile

Transport and binding proteins: Unknown substrate

IDP05078
(show subtarget assignments)

1

soluble

No

lmo1340

16803380

-

hypothetical protein lmo1340 [Listeria m...

363

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

Listeria monocytogenes

Transport and binding proteins: Unknown substrate

IDP05364
(show subtarget assignments)

1

soluble

No

BA_2881

30257478

bacterial extracellular solute-binding p...

578

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3M8U

19.2%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05631
(show subtarget assignments)

1

crystallized

No

CD1979

126699588

ABC transporter, substrate-binding prote...

337

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3IX1

26.4%

Clostridium difficile

Transport and binding proteins: Unknown substrate

IDP05181
(show subtarget assignments)

1

soluble

No

BA_4729

30259221

bacterial extracellular solute-binding p...

521

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1UQW

30.3%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05760
(show subtarget assignments)

1

purified

No

lmo1959

16803998

-

hypothetical protein lmo1959 [Listeria m...

303

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3HXP

37%

Listeria monocytogenes

Transport and binding proteins: Unknown substrate

IDP05694
(show subtarget assignments)

1

soluble

No

lmo2007

16804046

-

hypothetical protein lmo2007 [Listeria m...

485

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3OMB

21.3%

Listeria monocytogenes

Transport and binding proteins: Unknown substrate

IDP05415
(show subtarget assignments)

1

soluble

No

BA_5219

30259700

putative ABC transporter, substrate-bind...

268

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

4EF1

49.6%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05245
(show subtarget assignments)

1

soluble

No

lmo2349

16804387

-

hypothetical protein lmo2349 [Listeria m...

269

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2O1M

71%

Listeria monocytogenes

Transport and binding proteins: Unknown substrate

IDP05708
(show subtarget assignments)

1

soluble

No

lmo2839

16804876

-

hypothetical protein lmo2839 [Listeria m...

430

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3QUF

24.4%

Listeria monocytogenes

Transport and binding proteins: Unknown substrate

IDP05197
(show subtarget assignments)

1

cloned

No

CD1131

126698725

putative solute-binding lipoprotein [Clo...

556

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3RQT

19.8%

Clostridium difficile

Transport and binding proteins: Unknown substrate

IDP05714
(show subtarget assignments)

1

purified

No

BA_0175

30253683

putative ABC transporter, substrate-bind...

270

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3K2D

37.8%

Bacillus anthracis

Transport and binding proteins: Unknown substrate

IDP05664
(show subtarget assignments)

1

purified

No

lmo0341

16802386

-

hypothetical protein lmo0341 [Listeria m...

110

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2IP6

30%

Listeria monocytogenes

Transport and binding proteins: Other

IDP05138
(show subtarget assignments)

1

cloned

No

CD2874

126700490

putative drug/sodium antiporter [Clostri...

446

virulence/pathogenesis / Targets associated with virulence and/or pathogenesis

Phase 5: 2010

Clostridium difficile

Transport and binding proteins: Other

IDP05294
(show subtarget assignments)

1

cloned

No

CD1418

126699021

putative drug/sodium antiporter [Clostri...

451

virulence/pathogenesis / Targets associated with virulence and/or pathogenesis

Phase 5: 2010

3MKT

20.6%

Clostridium difficile

Transport and binding proteins: Other

IDP05398
(show subtarget assignments)

1

soluble

No

BA_3750

30258269

putative phosphonate ABC transporter, ph...

312

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3N5L

21.8%

Bacillus anthracis

Transport and binding proteins: Other

IDP05738
(show subtarget assignments)

1

cloned

No

CD2090

126699707

putative xanthine/uracile permease [Clos...

453

essential/virulence/pathogenesis / Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...

Phase 5: 2010

3QE7

28%

Clostridium difficile

Transport and binding proteins: Nucleosides, purines and pyrimidines

IDP05678
(show subtarget assignments)

1

in_crystallization_trials

No

lmo1041

16803081

-

hypothetical protein lmo1041 [Listeria m...

256

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1AMF

30.9%

Listeria monocytogenes

Transport and binding proteins: Cations and iron carrying compounds

IDP05715
(show subtarget assignments)

1

purified

No

BA_0351

30253889

iron compound ABC transporter, iron comp...

305

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3HXP

36.1%

Bacillus anthracis

Transport and binding proteins: Cations and iron carrying compounds

IDP05050
(show subtarget assignments)

1

purified

No

BA_5330

30259806

iron compound ABC transporter, iron comp...

333

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3GFV

26.4%

Bacillus anthracis

Transport and binding proteins: Cations and iron carrying compounds

IDP05404
(show subtarget assignments)

1

soluble

No

BA_5628

30260080

iron compound ABC transporter, iron comp...

314

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3HXP

29.6%

Bacillus anthracis

Transport and binding proteins: Cations and iron carrying compounds

IDP05227
(show subtarget assignments)

1

soluble

No

lmo0541

16802584

-

hypothetical protein lmo0541 [Listeria m...

306

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3EIW

28.1%

Listeria monocytogenes

Transport and binding proteins: Cations and iron carrying compounds

IDP05369
(show subtarget assignments)

1

soluble

No

BA_4597

30259097

iron compound ABC transporter, iron comp...

315

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2PHZ

27%

Bacillus anthracis

Transport and binding proteins: Cations and iron carrying compounds

IDP05674
(show subtarget assignments)

1

soluble

No

lmo0859

16802900

-

hypothetical protein lmo0859 [Listeria m...

439

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3QUF

23.7%

Listeria monocytogenes

Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05349
(show subtarget assignments)

1

cloned

No

CD2487

126700104

PTS system, IIB component [Clostridium d...

105

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2KYR

67.6%

Clostridium difficile

Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05311
(show subtarget assignments)

1

cloned

No

CD3014

126700634

PTS system, IIB component [Clostridium d...

106

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2R4Q

45.3%

Clostridium difficile

Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05707
(show subtarget assignments)

1

expressed

No

lmo2762

16804799

-

hypothetical protein lmo2762 [Listeria m...

100

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1H9C

44%

Listeria monocytogenes

Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05591
(show subtarget assignments)

1

purified

No

BA_2975

30257565

putative sugar ABC transporter, sugar-bi...

347

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1TJY

57.1%

Bacillus anthracis

Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05433
(show subtarget assignments)

1

soluble

No

lmo1730

16803770

-

hypothetical protein lmo1730 [Listeria m...

414

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3UOR

33.6%

Listeria monocytogenes

Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05406
(show subtarget assignments)

1

in_crystallization_trials

No

BA_0669

30254269

rbsB

ribose ABC transporter, ribose-binding p...

308

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2IOY

51.9%

Bacillus anthracis

Transport and binding proteins: Carbohydrates, organic alcohols, and acids

IDP05042
(show subtarget assignments)

1

soluble

No

BA_2921

30257513

putative sulfonate ABC transporter, sulf...

328

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2X26

28%

Bacillus anthracis

Transport and binding proteins: Anions

IDP05504
(show subtarget assignments)

1

purified

No

CD0869

126698446

modA

putative molybdenum ABC transporter,subs...

270

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1AMF

31.9%

Clostridium difficile

Transport and binding proteins: Anions

IDP05439
(show subtarget assignments)

1

soluble

No

lmo2499

16804537

-

hypothetical protein lmo2499 [Listeria m...

302

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

4ECF

53.6%

Listeria monocytogenes

Transport and binding proteins: Anions

IDP05158
(show subtarget assignments)

1

cloned

No

BA_1197

30255150

oligopeptide ABC transporter, oligopepti...

532

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3O9P

29.7%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05157
(show subtarget assignments)

1

soluble

No

BA_1191

30254904

oligopeptide ABC transporter, oligopepti...

543

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1B05

29.3%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05153
(show subtarget assignments)

1

soluble

No

BA_0656

30254258

oligopeptide ABC transporter, oligopepti...

593

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3DRF

32.4%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05150
(show subtarget assignments)

1

in_crystallization_trials

No

BA_0195

30253702

putative oligopeptide ABC transporter, o...

546

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1B05

29.9%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05149
(show subtarget assignments)

1

purified

No

BA_0194

30253701

putative oligopeptide ABC transporter, o...

546

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1B05

30.2%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05673
(show subtarget assignments)

1

soluble

No

lmo0810

16802852

-

hypothetical protein lmo0810 [Listeria m...

357

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

4EQB

54.6%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05135
(show subtarget assignments)

1

soluble

No

CD0855

126698435

oppA

oligopeptide ABC transporter, substrate-...

522

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1XOC

33.1%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05561
(show subtarget assignments)

1

cloned

No

lmo2026

16804065

-

peptidoglycan binding protein [Listeria ...

626

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1M0Z

11%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05549
(show subtarget assignments)

1

soluble

No

lmo0549

16802592

-

hypothetical protein lmo0549 [Listeria m...

673

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1M9S

14.6%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05100
(show subtarget assignments)

1

soluble

No

CD0876

126698453

ABC transporter, substrate-binding lipop...

345

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3LFT

32.2%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05699
(show subtarget assignments)

1

cloned

No

lmo2396

16804434

-

hypothetical protein lmo2396 [Listeria m...

940

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1O6S

10.9%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05081
(show subtarget assignments)

1

expressed

No

lmo2027

16804066

-

putative cell surface protein, internali...

367

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2Y5Q

23.2%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05074
(show subtarget assignments)

1

cloned

No

lmo0135

16802183

-

hypothetical protein lmo0135 [Listeria m...

524

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1XOC

32.4%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05634
(show subtarget assignments)

1

soluble

No

CD2174

126699790

amino-acid ABC transporter,substrate-bin...

270

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2IEE

29.3%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05633
(show subtarget assignments)

1

purified

No

CD2177

126699793

amino-acid ABC transporter,substrate-bin...

267

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2IEE

32.6%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05525
(show subtarget assignments)

1

soluble

No

CD2550

126700167

putative sugar transporter, substrate-bi...

430

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1EU8

25.8%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05035
(show subtarget assignments)

1

in_crystallization_trials

No

BA_1300

30255245

potD

spermidine/putrescine ABC transporter, s...

345

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1POT

35.7%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05031
(show subtarget assignments)

1

soluble

No

BA_0908

30254654

oligopeptide ABC transporter, oligopepti...

528

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1XOC

30.7%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05027
(show subtarget assignments)

1

purified

No

BA_0231

30253731

putative oligopeptide ABC transporter, o...

555

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3DRF

27.3%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05020
(show subtarget assignments)

1

soluble

No

CD1027

126698611

potD

spermidine/putrescine ABC transporter,su...

350

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

4EQB

39.1%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05622
(show subtarget assignments)

1

soluble

No

CD0999

126698583

ABC transporter, substrate-binding lipop...

331

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3HN0

24.2%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05021
(show subtarget assignments)

1

soluble

No

CD1139

126698733

rnfG

electron transport complex protein [Clos...

189

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05319
(show subtarget assignments)

1

soluble

No

BA_2848

30257448

putative oligopeptide ABC transporter, o...

540

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2Z23

29.3%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05180
(show subtarget assignments)

1

soluble

No

BA_3644

30258169

putative oligopeptide ABC transporter, o...

568

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3TCF

29.6%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05630
(show subtarget assignments)

1

soluble

No

CD1774

126699383

amino acid ABC transporter, substrate-bi...

267

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3HV1

36%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines

IDP05599
(show subtarget assignments)

1

purified

No

BA_3642

30258168

putative oligopeptide ABC transporter, o...

568

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1B05

28.9%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05711
(show subtarget assignments)

1

soluble

No

BAS1732

49184745

-

oligopeptide ABC transporter, solute bin...

519

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1B05

28.5%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05446
(show subtarget assignments)

1

soluble

No

lmo1738

16803778

-

hypothetical protein lmo1738 [Listeria m...

271

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3HV1

49.4%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05600
(show subtarget assignments)

1

soluble

No

BA_3645

30258170

putative oligopeptide ABC transporter, o...

562

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1B05

29.5%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05431
(show subtarget assignments)

1

cloned

No

lmo1224

16803264

-

hypothetical protein lmo1224 [Listeria m...

1136

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05579
(show subtarget assignments)

1

soluble

No

BA_0855

30254440

amino acid ABC transporter, amino acid-b...

265

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2YLN

40.8%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05270
(show subtarget assignments)

1

soluble

No

lmo1016

16803056

gbuC

hypothetical protein lmo1016 [Listeria m...

249

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

2B4L

51%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05713
(show subtarget assignments)

1

cloned

No

BA_0189

30253696

oligopeptide ABC transporter, oligopepti...

536

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

1B05

31.2%

Bacillus anthracis

Transport and binding proteins: Amino acids, peptides and amines

IDP05685
(show subtarget assignments)

1

soluble

No

lmo1426

16803466

opuCC

hypothetical protein lmo1426 [Listeria m...

308

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3PPN

57.1%

Listeria monocytogenes

Transport and binding proteins: Amino acids, peptides and amines

IDP05207
(show subtarget assignments)

1

cloned

No

CD2365

126699980

putative sulfonate ABC transporter,solut...

363

associated with virulence and/or pathogenesis; vaccine candidate

Phase 5: 2010

3QSL

20.4%

Clostridium difficile

Transport and binding proteins: Amino acids, peptides and amines