Center for Structural Genomics of Infectious Diseases


CSGID ID	Priority	stage	Screening	Locus Tag	NCBI GI	Gene Name	Common Name	Sequence Length	Justification	Selection Phase	Homolog PDB ID	Homolog Sequence Identity	Target Organism	TIGR Main Role	TIGR Subrole	Request Person
IDP01514 (show subtarget assignments)	1	purified	No	VCA0518	15601278		fructose-specific PTS IIA/HPr components...	400	Conserved Gene / Pathway	Phase 2: March 2008	1A3A	11.5%	Vibrio cholerae	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP01513 (show subtarget assignments)	1	purified	No	VC1312	161582006	alr	alanine racemase	407	Conserved Gene / Pathway	Phase 2: March 2008	4ECL	26%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01511 (show subtarget assignments)	1	expressed	No	VC0794	15640812		hypothetical protein VC0794	139	Conserved Gene / Pathway	Phase 2: March 2008			Vibrio cholerae	Transport and binding proteins	Cations and iron carrying compounds

IDP01510 (show subtarget assignments)	1	in_crystallization_trials	No	VC0731	15640750		antioxidant, AhpC/Tsa family	207	Conserved Gene / Pathway	Phase 2: March 2008	1ZOF	55.1%	Vibrio cholerae	Cellular processes	Detoxification

IDP01508 (show subtarget assignments)	1	expressed	No	VCA0127	15600898		ribose ABC transporter protein	156	Conserved Gene / Pathway	Phase 2: March 2008	3DSA	48.1%	Vibrio cholerae	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP01507 (show subtarget assignments)	1	in_crystallization_trials	No	VC2045	15642047		superoxide dismutase, Fe	194	Conserved Gene / Pathway	Phase 2: March 2008	2W7W	86.6%	Vibrio cholerae	Cellular processes	Detoxification

IDP01506 (show subtarget assignments)	1	in_crystallization_trials	No	VCA1113	15601861		spermidine/putrescine ABC transporter, p...	343	Conserved Gene / Pathway	Phase 2: March 2008	1POT	37.6%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01505 (show subtarget assignments)	1	expressed	No	VCA1037	15601788		amino acid ABC transporter, ATP-binding ...	239	Conserved Gene / Pathway	Phase 2: March 2008	2OLJ	52.5%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01504 (show subtarget assignments)	1	expressed	No	VCA1028	15601781	lamB	maltoporin	416	Conserved Gene / Pathway	Phase 2: March 2008	1AF6	32.7%	Vibrio cholerae	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP00763 (show subtarget assignments)	1	expressed	No	SACOL0262	57286722		Ccholoylglycine hydrolase family protein...	330	Conserved Gene / Pathway	Phase 2: March 2008	2OQC	32.4%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP01503 (show subtarget assignments)	1	soluble	No	VCA0978	15601731		amino acid ABC transporter, periplasmic ...	243	Conserved Gene / Pathway	Phase 2: March 2008	1HPB	26.3%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01502 (show subtarget assignments)	1	expressed	No	VCA0977	15601730		ABC transporter, ATP-binding protein	539	Conserved Gene / Pathway	Phase 2: March 2008	3BK7	23.7%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP00762 (show subtarget assignments)	1	purified	No	SACOL0209	57286673		staphylocoagulase precursor	636	Conserved Gene / Pathway	Phase 2: March 2008	2A1D	29.4%	Staphylococcus aureus	Cellular processes	Pathogenesis

IDP01501 (show subtarget assignments)	1	expressed	No	VCA0946	15601699		maltose/maltodextrin transporter ATP-bin...	373	Conserved Gene / Pathway	Phase 2: March 2008	1Q12	67.3%	Vibrio cholerae	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP01500 (show subtarget assignments)	1	in_crystallization_trials	No	VCA0945	15601698	malE	maltose ABC transporter periplasmic prot...	406	Conserved Gene / Pathway	Phase 2: March 2008	3JYR	65%	Vibrio cholerae	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP00416 (show subtarget assignments)	1	expressed	No	YPO1212	16121503		2Fe-2S ferredoxin YfaE	85	Conserved Gene / Pathway	Phase 2: March 2008	3AV8	33.3%	Yersinia pestis	Energy metabolism	Electron transport

IDP00758 (show subtarget assignments)	1	soluble	No	SACOL0140	57285343	cap5E	capsular polysaccharide biosynthesis pro...	342	Conserved Gene / Pathway	Phase 2: March 2008	2GN4	38%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP01498 (show subtarget assignments)	1	expressed	No	VCA0862	15601617		long-chain fatty acid transport protein ...	412	Conserved Gene / Pathway	Phase 2: March 2008	1T16	39.2%	Vibrio cholerae	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP01497 (show subtarget assignments)	1	in_crystallization_trials	No	VCA0820	15601575	groEL	chaperonin GroEL	530	Conserved Gene / Pathway	Phase 2: March 2008	1AON	74.2%	Vibrio cholerae	Protein fate	Protein folding and stabilization

IDP00757 (show subtarget assignments)	1	soluble	No	SACOL0135	57285338		alcohol dehydrogenase, iron-containing	869	Conserved Gene / Pathway	Phase 2: March 2008	3MY7	25.3%	Staphylococcus aureus	Energy metabolism	Fermentation

IDP00756 (show subtarget assignments)	1	soluble	No	SACOL0115	57286664		glycosyl transferase, group 1 family pro...	388	Conserved Gene / Pathway	Phase 2: March 2008	3C48	21.8%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP01494 (show subtarget assignments)	1	purified	No	VCA0780	15601535		UDP-glucose 6-dehydrogenase	388	Conserved Gene / Pathway	Phase 2: March 2008	3PHL	71.1%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00755 (show subtarget assignments)	1	cloned	No	SACOL0099	57286648	sirA	iron compound ABC transporter, iron comp...	330	Conserved Gene / Pathway	Phase 2: March 2008	3MWF	89.1%	Staphylococcus aureus	Cell envelope	Other

IDP01492 (show subtarget assignments)	1	purified	No	VCA0702	15601458		iron-containing alcohol dehydrogenase	382	Conserved Gene / Pathway	Phase 2: March 2008	1OJ7	50.8%	Vibrio cholerae	Energy metabolism	Fermentation

IDP00414 (show subtarget assignments)	1	expressed	No	YPO1322	16121604	deoR	DNA-binding transcriptional repressor	254	Conserved Gene / Pathway	Phase 2: March 2008			Yersinia pestis	Cellular processes	Toxin production and resistance

IDP01491 (show subtarget assignments)	1	soluble	No	VCA0603	15601361		ABC transporter, periplasmic substrate-b...	339	Conserved Gene / Pathway	Phase 2: March 2008	1Y4T	18.3%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP01490 (show subtarget assignments)	1	expressed	No	VCA0602	15601360		ABC transporter, ATP-binding protein	403	Conserved Gene / Pathway	Phase 2: March 2008	2IT1	34%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP00754 (show subtarget assignments)	0	work_stopped	No	SACOL0095	57286644	spa	immunoglobulin G binding protein A precu...	508	Conserved Gene / Pathway	Phase 2: March 2008	1BDC	11.6%	Staphylococcus aureus	Cellular processes	Pathogenesis

IDP01489 (show subtarget assignments)	1	cloned	No	VCA0591	15601350		peptide ABC transporter, periplasmic pep...	611	Conserved Gene / Pathway	Phase 2: March 2008	1ZTY	21.8%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01488 (show subtarget assignments)	1	in_crystallization_trials	No	VCA0572	15601331	ddl	D-alanyl-alanine synthetase A	334	Conserved Gene / Pathway	Phase 2: March 2008	2FB9	34.1%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00753 (show subtarget assignments)	1	cloned	No	SACOL0052	57286607		glycosyl transferase, group 1 family pro...	503	Conserved Gene / Pathway	Phase 2: March 2008	2F9F	9.1%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP01486 (show subtarget assignments)	1	in_pdb 3IEB 3JR2	No	VCA0242	15601010	ulaD	3-keto-L-gulonate-6-phosphate decarboxyl...	215	Conserved Gene / Pathway	Phase 2: March 2008	3IEB	100%	Vibrio cholerae	Energy metabolism	Sugars

IDP01485 (show subtarget assignments)	1	soluble	No	VCA0220	15600989		hemolysin secretion protein HylB	548	Conserved Gene / Pathway	Phase 2: March 2008	3ZX6	16.4%	Vibrio cholerae	Transport and binding proteins	Other

IDP01484 (show subtarget assignments)	1	in_pdb 4EH1	No	VCA0183	15600953		nitric oxide dioxygenase	394	Conserved Gene / Pathway	Phase 2: March 2008	4EH1	61.7%	Vibrio cholerae	Transport and binding proteins	Cations and iron carrying compounds

IDP01482 (show subtarget assignments)	1	in_pdb 3QU1	No	VCA0150	15600920	def	peptide deformylase	168	Conserved Gene / Pathway	Phase 2: March 2008	3QU1	100%	Vibrio cholerae	Protein fate	Protein modification and repair

IDP01481 (show subtarget assignments)	1	expressed	No	VCA0130	15600901		D-ribose transporter subunit RbsB	294	Conserved Gene / Pathway	Phase 2: March 2008	1DBP	65.3%	Vibrio cholerae	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP01479 (show subtarget assignments)	1	expressed	No	VCA0064	15600835		TonB system receptor, putative	713	Conserved Gene / Pathway	Phase 2: March 2008	1NQF	22.6%	Vibrio cholerae	Transport and binding proteins	Cations and iron carrying compounds

IDP01478 (show subtarget assignments)	1	purified	No	VC2772	15642765		ParB family protein	293	Conserved Gene / Pathway	Phase 2: March 2008	1VZ0	33.8%	Vibrio cholerae	Cellular processes	Cell division

IDP00410 (show subtarget assignments)	1	cloned	No	YPO0548	16120876	ftsL	cell division protein FtsL	105	Conserved Gene / Pathway	Phase 2: March 2008			Yersinia pestis	Cellular processes	Cell division

IDP01476 (show subtarget assignments)	1	soluble	No	VC2694	15642689		superoxide dismutase, Mn	222	Conserved Gene / Pathway	Phase 2: March 2008	2RCV	48.2%	Vibrio cholerae	Cellular processes	Detoxification

IDP01475 (show subtarget assignments)	1	in_crystallization_trials	No	VC2675	15642670		ATP-dependent protease peptidase subunit...	185	Conserved Gene / Pathway	Phase 2: March 2008	1E94	78.4%	Vibrio cholerae	Protein fate	Degradation of proteins, peptides, and glycopeptides

IDP01474 (show subtarget assignments)	1	expressed	No	VC2657	15642652		fumarate reductase iron-sulfur subunit	252	Conserved Gene / Pathway	Phase 2: March 2008	1KF6	69%	Vibrio cholerae	Energy metabolism	Anaerobic

IDP01473 (show subtarget assignments)	1	soluble	No	VC2653	15642648		preprotein translocase subunit SecB	154	Conserved Gene / Pathway	Phase 2: March 2008	1QYN	66.2%	Vibrio cholerae	Protein fate	Protein and peptide secretion and trafficking

IDP01472 (show subtarget assignments)	1	cloned	No	VC2631	15642626		fimbrial assembly protein PilP, putative...	172	Conserved Gene / Pathway	Phase 2: March 2008	2LC4	16.3%	Vibrio cholerae	Cell envelope	Surface structures

IDP00409 (show subtarget assignments)	1	purified	No	YPO1601	16121869	fabF	3-oxoacyl-(acyl carrier protein) synthas...	413	Conserved Gene / Pathway	Phase 2: March 2008	1B3N	89.1%	Yersinia pestis	Cellular processes	Toxin production and resistance

IDP01471 (show subtarget assignments)	1	purified	No	VC2613	15642608		phosphoribulokinase	289	Conserved Gene / Pathway	Phase 2: March 2008	1A7J	51.6%	Vibrio cholerae	Energy metabolism	Sugars

IDP01470 (show subtarget assignments)	1	purified	No	VC2608	15642603		ABC transporter, ATP-binding protein	664	Conserved Gene / Pathway	Phase 2: March 2008	2IW3	23.8%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP01469 (show subtarget assignments)	1	purified	No	VC2568	15642563		peptidyl-prolyl cis-trans isomerase, FKB...	209	Conserved Gene / Pathway	Phase 2: March 2008	1FD9	40.2%	Vibrio cholerae	Protein fate	Protein folding and stabilization

IDP01468 (show subtarget assignments)	1	purified	No	VC2553	15642548		ABC transporter, ATP-binding protein, au...	238	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	32.8%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP00408 (show subtarget assignments)	1	cloned	No	YPO2735	16122939	ccmB	heme exporter protein B	219	Conserved Gene / Pathway	Phase 2: March 2008			Yersinia pestis	Protein fate	Protein and peptide secretion and trafficking

IDP01467 (show subtarget assignments)	1	purified	No	VC2549	15642544		methionine sulfoxide reductase A	212	Conserved Gene / Pathway	Phase 2: March 2008	2GT3	56.1%	Vibrio cholerae	Protein fate	Protein modification and repair

IDP01466 (show subtarget assignments)	1	in_crystallization_trials	No	VC2542	15642537		UDP-N-acetylmuramate:L-alanyl-gamma-D-gl...	451	Conserved Gene / Pathway	Phase 2: March 2008	3HN7	51%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01465 (show subtarget assignments)	1	purified	No	VC2528	15642523		ABC transporter, ATP-binding protein	241	Conserved Gene / Pathway	Phase 2: March 2008	1JI0	33.6%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP01464 (show subtarget assignments)	1	soluble	No	VC2520	15642516		ABC transporter, ATP-binding protein	267	Conserved Gene / Pathway	Phase 2: March 2008	3FVQ	34.5%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP01460 (show subtarget assignments)	1	cloned	No	VC2423	15642420		fimbrial protein	167	Conserved Gene / Pathway	Phase 2: March 2008	1OQW	37.1%	Vibrio cholerae	Cell envelope	Surface structures

IDP01459 (show subtarget assignments)	1	soluble	No	VC2420	161581987		flavodoxin	172	Conserved Gene / Pathway	Phase 2: March 2008	1AG9	45.3%	Vibrio cholerae	Energy metabolism	Electron transport

IDP00405 (show subtarget assignments)	1	purified	No	YPO4025	16124148		putative iron ABC transporter, ATP-bindi...	252	Conserved Gene / Pathway	Phase 2: March 2008	3FVQ	31.3%	Yersinia pestis	Transport and binding proteins	Unknown substrate

IDP01456 (show subtarget assignments)	1	purified	No	VC2406	15642403	murE	UDP-N-acetylmuramoylalanyl-D-glutamate--...	512	Conserved Gene / Pathway	Phase 2: March 2008	1E8C	50.6%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01455 (show subtarget assignments)	1	purified	No	VC2405	15642402		UDP-N-acetylmuramoylalanyl-D-glutamyl-2,...	453	Conserved Gene / Pathway	Phase 2: March 2008	1GG4	52.5%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01454 (show subtarget assignments)	1	purified	No	VC2403	161581989	murD	UDP-N-acetylmuramoyl-L-alanyl-D-glutamat...	444	Conserved Gene / Pathway	Phase 2: March 2008	1E0D	51.8%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01453 (show subtarget assignments)	1	cloned	No	VC2401	15642398	murG	N-acetylglucosaminyl transferase	354	Conserved Gene / Pathway	Phase 2: March 2008	1F0K	63.8%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01452 (show subtarget assignments)	1	soluble	No	VC2400	15642397	murC	UDP-N-acetylmuramate--L-alanine ligase	506	Conserved Gene / Pathway	Phase 2: March 2008	2F00	69.4%	Vibrio cholerae	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01451 (show subtarget assignments)	1	purified	No	VC2305	15642303		outer membrane protein OmpK	296	Conserved Gene / Pathway	Phase 2: March 2008	1TLW	26%	Vibrio cholerae	Transport and binding proteins	Nucleosides, purines and pyrimidines

IDP00403 (show subtarget assignments)	1	soluble	No	YPO1125	16121425	pal	peptidoglycan-associated outer membrane ...	168	Conserved Gene / Pathway	Phase 2: March 2008	1OAP	58.3%	Yersinia pestis	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00733 (show subtarget assignments)	1	selected	No	SACOL2419	57285149	hlgA	gamma-hemolysin, component A	309	Conserved Gene / Pathway	Phase 2: March 2008	2QK7	90.9%	Staphylococcus aureus	Cellular processes	Toxin production and resistance

IDP01448 (show subtarget assignments)	1	cloned	No	VC2213	15642211		outer membrane protein OmpA	321	Conserved Gene / Pathway	Phase 2: March 2008	3NB3	34.7%	Vibrio cholerae	Cell envelope	Other

IDP01447 (show subtarget assignments)	1	in_crystallization_trials	No	VC2181	15642180	lolB	outer membrane lipoprotein LolB	211	Conserved Gene / Pathway	Phase 2: March 2008	1IWM	30.3%	Vibrio cholerae	Cell envelope	Other

IDP01446 (show subtarget assignments)	1	in_crystallization_trials	No	VC2099	15642099		flavodoxin FldA	175	Conserved Gene / Pathway	Phase 2: March 2008	1AG9	75.4%	Vibrio cholerae	Energy metabolism	Electron transport

IDP00732 (show subtarget assignments)	1	in_crystallization_trials	No	SACOL2473	57286467		peptide ABC transporter, ATP-binding pro...	271	Conserved Gene / Pathway	Phase 2: March 2008	3DHW	31.7%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP01445 (show subtarget assignments)	1	soluble	No	VC2088	15642088	sdhB	succinate dehydrogenase iron-sulfur subu...	236	Conserved Gene / Pathway	Phase 2: March 2008	1NEK	77.2%	Vibrio cholerae	Energy metabolism	TCA cycle

IDP01444 (show subtarget assignments)	1	soluble	No	VC2081	15642081		zinc ABC transporter, periplasmic zinc-b...	297	Conserved Gene / Pathway	Phase 2: March 2008	2OGW	44.3%	Vibrio cholerae	Transport and binding proteins	Cations and iron carrying compounds

IDP00731 (show subtarget assignments)	1	purified	No	SACOL2462	57286457		ABC transporter, ATP-binding protein	220	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	35.5%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00402 (show subtarget assignments)	1	purified	No	YPO3182	16123344	ribH	riboflavin synthase subunit beta	156	Conserved Gene / Pathway	Phase 2: March 2008	3MK3	82.1%	Yersinia pestis	Biosynthesis of cofactors, prosthetic groups, and carriers	Riboflavin, FMN, and FAD

IDP01443 (show subtarget assignments)	1	soluble	No	VC2061	15642061		ParA family protein	258	Conserved Gene / Pathway	Phase 2: March 2008	1WCV	34.1%	Vibrio cholerae	Cellular processes	Cell division

IDP01442 (show subtarget assignments)	1	expressed	No	VC2048	15642050		vacJ lipoprotein	254	Conserved Gene / Pathway	Phase 2: March 2008			Vibrio cholerae	Cell envelope	Other

IDP00730 (show subtarget assignments)	1	soluble	No	SACOL2453	57286449		amino acid ABC transporter, ATP-binding ...	408	Conserved Gene / Pathway	Phase 2: March 2008	2IT1	27.5%	Staphylococcus aureus	Transport and binding proteins	Amino acids, peptides and amines

IDP00729 (show subtarget assignments)	1	purified	No	SACOL2356	57285089		ABC transporter, ATP-binding protein	221	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	37.1%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00728 (show subtarget assignments)	1	cloned	No	SACOL2210	57284991		ABC transporter, ATP-binding protein	286	Conserved Gene / Pathway	Phase 2: March 2008	3GFO	32.2%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00727 (show subtarget assignments)	1	cloned	No	SACOL2036	57284905		ABC transporter, ATP-binding protein	642	Conserved Gene / Pathway	Phase 2: March 2008	2IW3	24.1%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP00726 (show subtarget assignments)	1	purified	No	SACOL1929	57286276		ABC transporter, ATP-binding protein, pu...	505	Conserved Gene / Pathway	Phase 2: March 2008			Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP01434 (show subtarget assignments)	1	purified	No	VC1944	15641946		PvcB protein	287	Conserved Gene / Pathway	Phase 2: March 2008	3EAT	46%	Vibrio cholerae	Transport and binding proteins	Cations and iron carrying compounds

IDP00725 (show subtarget assignments)	1	cloned	No	SACOL1919	57284837		transcriptional regulator, Fur family	148	Conserved Gene / Pathway	Phase 2: March 2008	2FE3	63.5%	Staphylococcus aureus	Transport and binding proteins	Cations and iron carrying compounds

IDP01431 (show subtarget assignments)	1	purified	No	VC1864	15641866		amino acid ABC transporter, ATP-binding ...	256	Conserved Gene / Pathway	Phase 2: March 2008	1B0U	62.9%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01430 (show subtarget assignments)	1	in_crystallization_trials	No	VC1863	15641865		amino acid ABC transporter, periplasmic ...	260	Conserved Gene / Pathway	Phase 2: March 2008	1LAF	39.2%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP00724 (show subtarget assignments)	1	in_crystallization_trials	No	SACOL1822	57286255	arsR	arsenical resistance operon repressor	104	Conserved Gene / Pathway	Phase 2: March 2008	1R1T	31.7%	Staphylococcus aureus	Cellular processes	Detoxification

IDP01429 (show subtarget assignments)	1	in_crystallization_trials	No	VC1849	15641851		peptidyl-prolyl cis-trans isomerase B	164	Conserved Gene / Pathway	Phase 2: March 2008	1LOP	64%	Vibrio cholerae	Protein fate	Protein folding and stabilization

IDP01427 (show subtarget assignments)	1	purified	No	VC1684	15641688		peptide ABC transporter, ATP-binding pro...	262	Conserved Gene / Pathway	Phase 2: March 2008	3DHW	33.6%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01426 (show subtarget assignments)	1	expressed	No	VC1680	15641684		peptide ABC transporter, periplasmic pep...	540	Conserved Gene / Pathway	Phase 2: March 2008	1DPP	35%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01425 (show subtarget assignments)	1	expressed	No	VC1630	15641635		ABC transporter, ATP-binding protein	227	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	37%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP01424 (show subtarget assignments)	1	purified	No	VC1568	15641576		ABC transporter, ATP-binding protein	233	Conserved Gene / Pathway	Phase 2: March 2008	1F3O	49.8%	Vibrio cholerae	Transport and binding proteins	Unknown substrate

IDP00721 (show subtarget assignments)	1	expressed	No	SACOL1613	57286135		ABC transporter, ATP-binding protein	261	Conserved Gene / Pathway	Phase 2: March 2008	2IT1	31.8%	Staphylococcus aureus	Transport and binding proteins	Unknown substrate

IDP01423 (show subtarget assignments)	1	purified	No	VC1552	15641560	ugpC	glycerol-3-phosphate ABC transporter, AT...	393	Conserved Gene / Pathway	Phase 2: March 2008	2D62	45.5%	Vibrio cholerae	Transport and binding proteins	Other

IDP01422 (show subtarget assignments)	1	expressed	No	VC1549	15641557		glycerol-3-phosphate ABC transporter, pe...	434	Conserved Gene / Pathway	Phase 2: March 2008	2HEU	20%	Vibrio cholerae	Transport and binding proteins	Other

IDP01421 (show subtarget assignments)	1	soluble	No	VC1544	15641552		tonB2 protein	206	Conserved Gene / Pathway	Phase 2: March 2008	2K9K	34%	Vibrio cholerae	Transport and binding proteins	Cations and iron carrying compounds

IDP00719 (show subtarget assignments)	1	in_crystallization_trials	No	SACOL1457	57284566		PTS system, IIA component	166	Conserved Gene / Pathway	Phase 2: March 2008	1GGR	41%	Staphylococcus aureus	Transport and binding proteins	Carbohydrates, organic alcohols, and acids

IDP01419 (show subtarget assignments)	1	in_crystallization_trials	No	VC1425	15641436		spermidine/putrescine ABC transporter, p...	366	Conserved Gene / Pathway	Phase 2: March 2008	1POT	52.7%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP01418 (show subtarget assignments)	1	purified	No	VC1424	15641435		spermidine/putrescine ABC transporter, p...	345	Conserved Gene / Pathway	Phase 2: March 2008	1POT	61.4%	Vibrio cholerae	Transport and binding proteins	Amino acids, peptides and amines

IDP00718 (show subtarget assignments)	1	soluble	No	SACOL1434	57286085		alanine racemase family protein	361	Conserved Gene / Pathway	Phase 2: March 2008	2RJG	27.1%	Staphylococcus aureus	Cell envelope	Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00717 (show subtarget assignments)	1	cloned	No	SACOL1421	57286072		phosphate ABC transporter, ATP-binding p...	283	Conserved Gene / Pathway	Phase 2: March 2008	2OLJ	32.9%	Staphylococcus aureus	Transport and binding proteins	Anions

IDP01416 (show subtarget assignments)	1	soluble	No	VC1410	15641421		multidrug resistance protein VceA	406	Conserved Gene / Pathway	Phase 2: March 2008	4DK1	15.3%	Vibrio cholerae	Transport and binding proteins	Other

IDP01514
(show subtarget assignments)

1

purified

No

VCA0518

15601278

fructose-specific PTS IIA/HPr components...

400

Conserved Gene / Pathway

Phase 2: March 2008

1A3A

11.5%

Vibrio cholerae

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP01513
(show subtarget assignments)

1

purified

No

VC1312

161582006

alr

alanine racemase

407

Conserved Gene / Pathway

Phase 2: March 2008

4ECL

26%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01511
(show subtarget assignments)

1

expressed

No

VC0794

15640812

hypothetical protein VC0794

139

Conserved Gene / Pathway

Phase 2: March 2008

Vibrio cholerae

Transport and binding proteins

Cations and iron carrying compounds

IDP01510
(show subtarget assignments)

1

in_crystallization_trials

No

VC0731

15640750

antioxidant, AhpC/Tsa family

207

Conserved Gene / Pathway

Phase 2: March 2008

1ZOF

55.1%

Vibrio cholerae

Cellular processes

Detoxification

IDP01508
(show subtarget assignments)

1

expressed

No

VCA0127

15600898

ribose ABC transporter protein

156

Conserved Gene / Pathway

Phase 2: March 2008

3DSA

48.1%

Vibrio cholerae

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP01507
(show subtarget assignments)

1

in_crystallization_trials

No

VC2045

15642047

superoxide dismutase, Fe

194

Conserved Gene / Pathway

Phase 2: March 2008

2W7W

86.6%

Vibrio cholerae

Cellular processes

Detoxification

IDP01506
(show subtarget assignments)

1

in_crystallization_trials

No

VCA1113

15601861

spermidine/putrescine ABC transporter, p...

343

Conserved Gene / Pathway

Phase 2: March 2008

1POT

37.6%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01505
(show subtarget assignments)

1

expressed

No

VCA1037

15601788

amino acid ABC transporter, ATP-binding ...

239

Conserved Gene / Pathway

Phase 2: March 2008

2OLJ

52.5%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01504
(show subtarget assignments)

1

expressed

No

VCA1028

15601781

lamB

maltoporin

416

Conserved Gene / Pathway

Phase 2: March 2008

1AF6

32.7%

Vibrio cholerae

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP00763
(show subtarget assignments)

1

expressed

No

SACOL0262

57286722

Ccholoylglycine hydrolase family protein...

330

Conserved Gene / Pathway

Phase 2: March 2008

2OQC

32.4%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP01503
(show subtarget assignments)

1

soluble

No

VCA0978

15601731

amino acid ABC transporter, periplasmic ...

243

Conserved Gene / Pathway

Phase 2: March 2008

1HPB

26.3%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01502
(show subtarget assignments)

1

expressed

No

VCA0977

15601730

ABC transporter, ATP-binding protein

539

Conserved Gene / Pathway

Phase 2: March 2008

3BK7

23.7%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP00762
(show subtarget assignments)

1

purified

No

SACOL0209

57286673

staphylocoagulase precursor

636

Conserved Gene / Pathway

Phase 2: March 2008

2A1D

29.4%

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP01501
(show subtarget assignments)

1

expressed

No

VCA0946

15601699

maltose/maltodextrin transporter ATP-bin...

373

Conserved Gene / Pathway

Phase 2: March 2008

1Q12

67.3%

Vibrio cholerae

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP01500
(show subtarget assignments)

1

in_crystallization_trials

No

VCA0945

15601698

malE

maltose ABC transporter periplasmic prot...

406

Conserved Gene / Pathway

Phase 2: March 2008

3JYR

65%

Vibrio cholerae

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP00416
(show subtarget assignments)

1

expressed

No

YPO1212

16121503

2Fe-2S ferredoxin YfaE

85

Conserved Gene / Pathway

Phase 2: March 2008

3AV8

33.3%

Yersinia pestis

Energy metabolism

Electron transport

IDP00758
(show subtarget assignments)

1

soluble

No

SACOL0140

57285343

cap5E

capsular polysaccharide biosynthesis pro...

342

Conserved Gene / Pathway

Phase 2: March 2008

2GN4

38%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP01498
(show subtarget assignments)

1

expressed

No

VCA0862

15601617

long-chain fatty acid transport protein ...

412

Conserved Gene / Pathway

Phase 2: March 2008

1T16

39.2%

Vibrio cholerae

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP01497
(show subtarget assignments)

1

in_crystallization_trials

No

VCA0820

15601575

groEL

chaperonin GroEL

530

Conserved Gene / Pathway

Phase 2: March 2008

1AON

74.2%

Vibrio cholerae

Protein fate

Protein folding and stabilization

IDP00757
(show subtarget assignments)

1

soluble

No

SACOL0135

57285338

alcohol dehydrogenase, iron-containing

869

Conserved Gene / Pathway

Phase 2: March 2008

3MY7

25.3%

Staphylococcus aureus

Energy metabolism

Fermentation

IDP00756
(show subtarget assignments)

1

soluble

No

SACOL0115

57286664

glycosyl transferase, group 1 family pro...

388

Conserved Gene / Pathway

Phase 2: March 2008

3C48

21.8%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP01494
(show subtarget assignments)

1

purified

No

VCA0780

15601535

UDP-glucose 6-dehydrogenase

388

Conserved Gene / Pathway

Phase 2: March 2008

3PHL

71.1%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP00755
(show subtarget assignments)

1

cloned

No

SACOL0099

57286648

sirA

iron compound ABC transporter, iron comp...

330

Conserved Gene / Pathway

Phase 2: March 2008

3MWF

89.1%

Staphylococcus aureus

Cell envelope

Other

IDP01492
(show subtarget assignments)

1

purified

No

VCA0702

15601458

iron-containing alcohol dehydrogenase

382

Conserved Gene / Pathway

Phase 2: March 2008

1OJ7

50.8%

Vibrio cholerae

Energy metabolism

Fermentation

IDP00414
(show subtarget assignments)

1

expressed

No

YPO1322

16121604

deoR

DNA-binding transcriptional repressor

254

Conserved Gene / Pathway

Phase 2: March 2008

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP01491
(show subtarget assignments)

1

soluble

No

VCA0603

15601361

ABC transporter, periplasmic substrate-b...

339

Conserved Gene / Pathway

Phase 2: March 2008

1Y4T

18.3%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP01490
(show subtarget assignments)

1

expressed

No

VCA0602

15601360

ABC transporter, ATP-binding protein

403

Conserved Gene / Pathway

Phase 2: March 2008

2IT1

34%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP00754
(show subtarget assignments)

0

work_stopped

No

SACOL0095

57286644

spa

immunoglobulin G binding protein A precu...

508

Conserved Gene / Pathway

Phase 2: March 2008

1BDC

11.6%

Staphylococcus aureus

Cellular processes

Pathogenesis

IDP01489
(show subtarget assignments)

1

cloned

No

VCA0591

15601350

peptide ABC transporter, periplasmic pep...

611

Conserved Gene / Pathway

Phase 2: March 2008

1ZTY

21.8%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01488
(show subtarget assignments)

1

in_crystallization_trials

No

VCA0572

15601331

ddl

D-alanyl-alanine synthetase A

334

Conserved Gene / Pathway

Phase 2: March 2008

2FB9

34.1%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00753
(show subtarget assignments)

1

cloned

No

SACOL0052

57286607

glycosyl transferase, group 1 family pro...

503

Conserved Gene / Pathway

Phase 2: March 2008

2F9F

9.1%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides

IDP01486
(show subtarget assignments)

1

in_pdb
3IEB
3JR2

No

VCA0242

15601010

ulaD

3-keto-L-gulonate-6-phosphate decarboxyl...

215

Conserved Gene / Pathway

Phase 2: March 2008

3IEB

100%

Vibrio cholerae

Energy metabolism

Sugars

IDP01485
(show subtarget assignments)

1

soluble

No

VCA0220

15600989

hemolysin secretion protein HylB

548

Conserved Gene / Pathway

Phase 2: March 2008

3ZX6

16.4%

Vibrio cholerae

Transport and binding proteins

Other

IDP01484
(show subtarget assignments)

1

in_pdb
4EH1

No

VCA0183

15600953

nitric oxide dioxygenase

394

Conserved Gene / Pathway

Phase 2: March 2008

4EH1

61.7%

Vibrio cholerae

Transport and binding proteins

Cations and iron carrying compounds

IDP01482
(show subtarget assignments)

1

in_pdb
3QU1

No

VCA0150

15600920

def

peptide deformylase

168

Conserved Gene / Pathway

Phase 2: March 2008

3QU1

100%

Vibrio cholerae

Protein fate

Protein modification and repair

IDP01481
(show subtarget assignments)

1

expressed

No

VCA0130

15600901

D-ribose transporter subunit RbsB

294

Conserved Gene / Pathway

Phase 2: March 2008

1DBP

65.3%

Vibrio cholerae

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP01479
(show subtarget assignments)

1

expressed

No

VCA0064

15600835

TonB system receptor, putative

713

Conserved Gene / Pathway

Phase 2: March 2008

1NQF

22.6%

Vibrio cholerae

Transport and binding proteins

Cations and iron carrying compounds

IDP01478
(show subtarget assignments)

1

purified

No

VC2772

15642765

ParB family protein

293

Conserved Gene / Pathway

Phase 2: March 2008

1VZ0

33.8%

Vibrio cholerae

Cellular processes

Cell division

IDP00410
(show subtarget assignments)

1

cloned

No

YPO0548

16120876

ftsL

cell division protein FtsL

105

Conserved Gene / Pathway

Phase 2: March 2008

Yersinia pestis

Cellular processes

Cell division

IDP01476
(show subtarget assignments)

1

soluble

No

VC2694

15642689

superoxide dismutase, Mn

222

Conserved Gene / Pathway

Phase 2: March 2008

2RCV

48.2%

Vibrio cholerae

Cellular processes

Detoxification

IDP01475
(show subtarget assignments)

1

in_crystallization_trials

No

VC2675

15642670

ATP-dependent protease peptidase subunit...

185

Conserved Gene / Pathway

Phase 2: March 2008

1E94

78.4%

Vibrio cholerae

Protein fate

Degradation of proteins, peptides, and glycopeptides

IDP01474
(show subtarget assignments)

1

expressed

No

VC2657

15642652

fumarate reductase iron-sulfur subunit

252

Conserved Gene / Pathway

Phase 2: March 2008

1KF6

69%

Vibrio cholerae

Energy metabolism

Anaerobic

IDP01473
(show subtarget assignments)

1

soluble

No

VC2653

15642648

preprotein translocase subunit SecB

154

Conserved Gene / Pathway

Phase 2: March 2008

1QYN

66.2%

Vibrio cholerae

Protein fate

Protein and peptide secretion and trafficking

IDP01472
(show subtarget assignments)

1

cloned

No

VC2631

15642626

fimbrial assembly protein PilP, putative...

172

Conserved Gene / Pathway

Phase 2: March 2008

2LC4

16.3%

Vibrio cholerae

Cell envelope

Surface structures

IDP00409
(show subtarget assignments)

1

purified

No

YPO1601

16121869

fabF

3-oxoacyl-(acyl carrier protein) synthas...

413

Conserved Gene / Pathway

Phase 2: March 2008

1B3N

89.1%

Yersinia pestis

Cellular processes

Toxin production and resistance

IDP01471
(show subtarget assignments)

1

purified

No

VC2613

15642608

phosphoribulokinase

289

Conserved Gene / Pathway

Phase 2: March 2008

1A7J

51.6%

Vibrio cholerae

Energy metabolism

Sugars

IDP01470
(show subtarget assignments)

1

purified

No

VC2608

15642603

ABC transporter, ATP-binding protein

664

Conserved Gene / Pathway

Phase 2: March 2008

2IW3

23.8%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP01469
(show subtarget assignments)

1

purified

No

VC2568

15642563

peptidyl-prolyl cis-trans isomerase, FKB...

209

Conserved Gene / Pathway

Phase 2: March 2008

1FD9

40.2%

Vibrio cholerae

Protein fate

Protein folding and stabilization

IDP01468
(show subtarget assignments)

1

purified

No

VC2553

15642548

ABC transporter, ATP-binding protein, au...

238

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

32.8%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP00408
(show subtarget assignments)

1

cloned

No

YPO2735

16122939

ccmB

heme exporter protein B

219

Conserved Gene / Pathway

Phase 2: March 2008

Yersinia pestis

Protein fate

Protein and peptide secretion and trafficking

IDP01467
(show subtarget assignments)

1

purified

No

VC2549

15642544

methionine sulfoxide reductase A

212

Conserved Gene / Pathway

Phase 2: March 2008

2GT3

56.1%

Vibrio cholerae

Protein fate

Protein modification and repair

IDP01466
(show subtarget assignments)

1

in_crystallization_trials

No

VC2542

15642537

UDP-N-acetylmuramate:L-alanyl-gamma-D-gl...

451

Conserved Gene / Pathway

Phase 2: March 2008

3HN7

51%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01465
(show subtarget assignments)

1

purified

No

VC2528

15642523

ABC transporter, ATP-binding protein

241

Conserved Gene / Pathway

Phase 2: March 2008

1JI0

33.6%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP01464
(show subtarget assignments)

1

soluble

No

VC2520

15642516

ABC transporter, ATP-binding protein

267

Conserved Gene / Pathway

Phase 2: March 2008

3FVQ

34.5%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP01460
(show subtarget assignments)

1

cloned

No

VC2423

15642420

fimbrial protein

167

Conserved Gene / Pathway

Phase 2: March 2008

1OQW

37.1%

Vibrio cholerae

Cell envelope

Surface structures

IDP01459
(show subtarget assignments)

1

soluble

No

VC2420

161581987

flavodoxin

172

Conserved Gene / Pathway

Phase 2: March 2008

1AG9

45.3%

Vibrio cholerae

Energy metabolism

Electron transport

IDP00405
(show subtarget assignments)

1

purified

No

YPO4025

16124148

putative iron ABC transporter, ATP-bindi...

252

Conserved Gene / Pathway

Phase 2: March 2008

3FVQ

31.3%

Yersinia pestis

Transport and binding proteins

Unknown substrate

IDP01456
(show subtarget assignments)

1

purified

No

VC2406

15642403

murE

UDP-N-acetylmuramoylalanyl-D-glutamate--...

512

Conserved Gene / Pathway

Phase 2: March 2008

1E8C

50.6%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01455
(show subtarget assignments)

1

purified

No

VC2405

15642402

UDP-N-acetylmuramoylalanyl-D-glutamyl-2,...

453

Conserved Gene / Pathway

Phase 2: March 2008

1GG4

52.5%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01454
(show subtarget assignments)

1

purified

No

VC2403

161581989

murD

UDP-N-acetylmuramoyl-L-alanyl-D-glutamat...

444

Conserved Gene / Pathway

Phase 2: March 2008

1E0D

51.8%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01453
(show subtarget assignments)

1

cloned

No

VC2401

15642398

murG

N-acetylglucosaminyl transferase

354

Conserved Gene / Pathway

Phase 2: March 2008

1F0K

63.8%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01452
(show subtarget assignments)

1

soluble

No

VC2400

15642397

murC

UDP-N-acetylmuramate--L-alanine ligase

506

Conserved Gene / Pathway

Phase 2: March 2008

2F00

69.4%

Vibrio cholerae

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP01451
(show subtarget assignments)

1

purified

No

VC2305

15642303

outer membrane protein OmpK

296

Conserved Gene / Pathway

Phase 2: March 2008

1TLW

26%

Vibrio cholerae

Transport and binding proteins

Nucleosides, purines and pyrimidines

IDP00403
(show subtarget assignments)

1

soluble

No

YPO1125

16121425

pal

peptidoglycan-associated outer membrane ...

168

Conserved Gene / Pathway

Phase 2: March 2008

1OAP

58.3%

Yersinia pestis

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00733
(show subtarget assignments)

1

selected

No

SACOL2419

57285149

hlgA

gamma-hemolysin, component A

309

Conserved Gene / Pathway

Phase 2: March 2008

2QK7

90.9%

Staphylococcus aureus

Cellular processes

Toxin production and resistance

IDP01448
(show subtarget assignments)

1

cloned

No

VC2213

15642211

outer membrane protein OmpA

321

Conserved Gene / Pathway

Phase 2: March 2008

3NB3

34.7%

Vibrio cholerae

Cell envelope

Other

IDP01447
(show subtarget assignments)

1

in_crystallization_trials

No

VC2181

15642180

lolB

outer membrane lipoprotein LolB

211

Conserved Gene / Pathway

Phase 2: March 2008

1IWM

30.3%

Vibrio cholerae

Cell envelope

Other

IDP01446
(show subtarget assignments)

1

in_crystallization_trials

No

VC2099

15642099

flavodoxin FldA

175

Conserved Gene / Pathway

Phase 2: March 2008

1AG9

75.4%

Vibrio cholerae

Energy metabolism

Electron transport

IDP00732
(show subtarget assignments)

1

in_crystallization_trials

No

SACOL2473

57286467

peptide ABC transporter, ATP-binding pro...

271

Conserved Gene / Pathway

Phase 2: March 2008

3DHW

31.7%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP01445
(show subtarget assignments)

1

soluble

No

VC2088

15642088

sdhB

succinate dehydrogenase iron-sulfur subu...

236

Conserved Gene / Pathway

Phase 2: March 2008

1NEK

77.2%

Vibrio cholerae

Energy metabolism

TCA cycle

IDP01444
(show subtarget assignments)

1

soluble

No

VC2081

15642081

zinc ABC transporter, periplasmic zinc-b...

297

Conserved Gene / Pathway

Phase 2: March 2008

2OGW

44.3%

Vibrio cholerae

Transport and binding proteins

Cations and iron carrying compounds

IDP00731
(show subtarget assignments)

1

purified

No

SACOL2462

57286457

ABC transporter, ATP-binding protein

220

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

35.5%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00402
(show subtarget assignments)

1

purified

No

YPO3182

16123344

ribH

riboflavin synthase subunit beta

156

Conserved Gene / Pathway

Phase 2: March 2008

3MK3

82.1%

Yersinia pestis

Biosynthesis of cofactors, prosthetic groups, and carriers

Riboflavin, FMN, and FAD

IDP01443
(show subtarget assignments)

1

soluble

No

VC2061

15642061

ParA family protein

258

Conserved Gene / Pathway

Phase 2: March 2008

1WCV

34.1%

Vibrio cholerae

Cellular processes

Cell division

IDP01442
(show subtarget assignments)

1

expressed

No

VC2048

15642050

vacJ lipoprotein

254

Conserved Gene / Pathway

Phase 2: March 2008

Vibrio cholerae

Cell envelope

Other

IDP00730
(show subtarget assignments)

1

soluble

No

SACOL2453

57286449

amino acid ABC transporter, ATP-binding ...

408

Conserved Gene / Pathway

Phase 2: March 2008

2IT1

27.5%

Staphylococcus aureus

Transport and binding proteins

Amino acids, peptides and amines

IDP00729
(show subtarget assignments)

1

purified

No

SACOL2356

57285089

ABC transporter, ATP-binding protein

221

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

37.1%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00728
(show subtarget assignments)

1

cloned

No

SACOL2210

57284991

ABC transporter, ATP-binding protein

286

Conserved Gene / Pathway

Phase 2: March 2008

3GFO

32.2%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00727
(show subtarget assignments)

1

cloned

No

SACOL2036

57284905

ABC transporter, ATP-binding protein

642

Conserved Gene / Pathway

Phase 2: March 2008

2IW3

24.1%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP00726
(show subtarget assignments)

1

purified

No

SACOL1929

57286276

ABC transporter, ATP-binding protein, pu...

505

Conserved Gene / Pathway

Phase 2: March 2008

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP01434
(show subtarget assignments)

1

purified

No

VC1944

15641946

PvcB protein

287

Conserved Gene / Pathway

Phase 2: March 2008

3EAT

46%

Vibrio cholerae

Transport and binding proteins

Cations and iron carrying compounds

IDP00725
(show subtarget assignments)

1

cloned

No

SACOL1919

57284837

transcriptional regulator, Fur family

148

Conserved Gene / Pathway

Phase 2: March 2008

2FE3

63.5%

Staphylococcus aureus

Transport and binding proteins

Cations and iron carrying compounds

IDP01431
(show subtarget assignments)

1

purified

No

VC1864

15641866

amino acid ABC transporter, ATP-binding ...

256

Conserved Gene / Pathway

Phase 2: March 2008

1B0U

62.9%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01430
(show subtarget assignments)

1

in_crystallization_trials

No

VC1863

15641865

amino acid ABC transporter, periplasmic ...

260

Conserved Gene / Pathway

Phase 2: March 2008

1LAF

39.2%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP00724
(show subtarget assignments)

1

in_crystallization_trials

No

SACOL1822

57286255

arsR

arsenical resistance operon repressor

104

Conserved Gene / Pathway

Phase 2: March 2008

1R1T

31.7%

Staphylococcus aureus

Cellular processes

Detoxification

IDP01429
(show subtarget assignments)

1

in_crystallization_trials

No

VC1849

15641851

peptidyl-prolyl cis-trans isomerase B

164

Conserved Gene / Pathway

Phase 2: March 2008

1LOP

64%

Vibrio cholerae

Protein fate

Protein folding and stabilization

IDP01427
(show subtarget assignments)

1

purified

No

VC1684

15641688

peptide ABC transporter, ATP-binding pro...

262

Conserved Gene / Pathway

Phase 2: March 2008

3DHW

33.6%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01426
(show subtarget assignments)

1

expressed

No

VC1680

15641684

peptide ABC transporter, periplasmic pep...

540

Conserved Gene / Pathway

Phase 2: March 2008

1DPP

35%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01425
(show subtarget assignments)

1

expressed

No

VC1630

15641635

ABC transporter, ATP-binding protein

227

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

37%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP01424
(show subtarget assignments)

1

purified

No

VC1568

15641576

ABC transporter, ATP-binding protein

233

Conserved Gene / Pathway

Phase 2: March 2008

1F3O

49.8%

Vibrio cholerae

Transport and binding proteins

Unknown substrate

IDP00721
(show subtarget assignments)

1

expressed

No

SACOL1613

57286135

ABC transporter, ATP-binding protein

261

Conserved Gene / Pathway

Phase 2: March 2008

2IT1

31.8%

Staphylococcus aureus

Transport and binding proteins

Unknown substrate

IDP01423
(show subtarget assignments)

1

purified

No

VC1552

15641560

ugpC

glycerol-3-phosphate ABC transporter, AT...

393

Conserved Gene / Pathway

Phase 2: March 2008

2D62

45.5%

Vibrio cholerae

Transport and binding proteins

Other

IDP01422
(show subtarget assignments)

1

expressed

No

VC1549

15641557

glycerol-3-phosphate ABC transporter, pe...

434

Conserved Gene / Pathway

Phase 2: March 2008

2HEU

20%

Vibrio cholerae

Transport and binding proteins

Other

IDP01421
(show subtarget assignments)

1

soluble

No

VC1544

15641552

tonB2 protein

206

Conserved Gene / Pathway

Phase 2: March 2008

2K9K

34%

Vibrio cholerae

Transport and binding proteins

Cations and iron carrying compounds

IDP00719
(show subtarget assignments)

1

in_crystallization_trials

No

SACOL1457

57284566

PTS system, IIA component

166

Conserved Gene / Pathway

Phase 2: March 2008

1GGR

41%

Staphylococcus aureus

Transport and binding proteins

Carbohydrates, organic alcohols, and acids

IDP01419
(show subtarget assignments)

1

in_crystallization_trials

No

VC1425

15641436

spermidine/putrescine ABC transporter, p...

366

Conserved Gene / Pathway

Phase 2: March 2008

1POT

52.7%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP01418
(show subtarget assignments)

1

purified

No

VC1424

15641435

spermidine/putrescine ABC transporter, p...

345

Conserved Gene / Pathway

Phase 2: March 2008

1POT

61.4%

Vibrio cholerae

Transport and binding proteins

Amino acids, peptides and amines

IDP00718
(show subtarget assignments)

1

soluble

No

SACOL1434

57286085

alanine racemase family protein

361

Conserved Gene / Pathway

Phase 2: March 2008

2RJG

27.1%

Staphylococcus aureus

Cell envelope

Biosynthesis and degradation of murein sacculus and peptidoglycan

IDP00717
(show subtarget assignments)

1

cloned

No

SACOL1421

57286072

phosphate ABC transporter, ATP-binding p...

283

Conserved Gene / Pathway

Phase 2: March 2008

2OLJ

32.9%

Staphylococcus aureus

Transport and binding proteins

Anions

IDP01416
(show subtarget assignments)

1

soluble

No

VC1410

15641421

multidrug resistance protein VceA

406

Conserved Gene / Pathway

Phase 2: March 2008

4DK1

15.3%

Vibrio cholerae

Transport and binding proteins

Other

Targets