|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene Name |
Common Name |
Sequence Length |
Selection Phase |
Homolog PDB ID |
Homolog Sequence Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP02503
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2502 |
16122723 |
gutB |
putative zinc-binding dehydrogenase [Yer... |
408 |
Phase 3: June 2008 |
2D8A
|
30.1% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Chlorophyll and bacteriochlorphyll |
|
|
|
IDP00507
(show subtarget assignments)
|
1 |
purified |
No |
YPO2511 |
16122732 |
|
hypothetical protein YPO2511 |
375 |
Phase 2: March 2008 |
|
|
Yersinia pestis |
Cell envelope |
Other |
|
|
|
IDP00474
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO2512 |
16122733 |
glnH |
glutamine ABC transporter periplasmic pr... |
247 |
Phase 2: March 2008 |
1GGG
|
78.1% |
Yersinia pestis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00464
(show subtarget assignments)
|
1 |
purified |
No |
YPO2522 |
16122741 |
|
hypothetical protein YPO2522 |
319 |
Phase 2: March 2008 |
1V8G
|
24.5% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP90737
(show subtarget assignments)
|
8 |
expressed |
No |
YPO2523 |
16122742 |
menE |
O-succinylbenzoic acid--CoA ligase [Yers... |
471 |
Community Requests |
3NYQ
|
32.4% |
Yersinia pestis |
|
|
|
|
|
IDP90631
(show subtarget assignments)
|
8 |
expressed |
No |
YPO2526 |
16122745 |
|
acyl-CoA thioester hydrolase YfbB [Yersi... |
272 |
Community Requests |
1R3D
|
42.3% |
Yersinia pestis |
|
|
|
|
|
IDP90830
(show subtarget assignments)
|
8 |
expressed |
No |
YPO2527 |
16122746 |
menD |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-... |
567 |
Community Requests |
2JLA
|
69% |
Yersinia pestis |
|
|
|
|
|
IDP00582
(show subtarget assignments)
|
1 |
in_pdb 3GSE |
Yes |
YPO2528 |
16122747 |
menF |
menaquinone-specific isochorismate synth... |
455 |
Phase 2: March 2008 |
3GSE
|
100% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP02336
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2533 |
16122751 |
edd |
phosphogluconate dehydratase [Yersinia p... |
625 |
Phase 3: June 2008 |
2GP4
|
63.8% |
Yersinia pestis |
Energy metabolism |
Entner-Doudoroff |
|
|
|
IDP02515
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2567 |
16122785 |
pta |
phosphate acetyltransferase [Yersinia pe... |
717 |
Phase 3: June 2008 |
1TD9
|
20.6% |
Yersinia pestis |
Energy metabolism |
Fermentation |
|
|
|
IDP01614
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO2581 |
16122794 |
|
putative sugar-binding periplasmic prote... |
309 |
Phase 3: June 2008 |
2IOY
|
29.5% |
Yersinia pestis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP91072
(show subtarget assignments)
|
8 |
cloned |
No |
YPO2588 |
16122801 |
- |
putative ABC transport protein |
631 |
Community Requests |
2HYD
|
32.2% |
Yersinia pestis |
|
|
|
|
|
IDP00417
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2604 |
16122817 |
pbpA |
penicillin-binding protein 2 |
631 |
Phase 2: March 2008 |
3OC2
|
26.1% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP90767
(show subtarget assignments)
|
8 |
soluble |
No |
YPO2607 |
16122820 |
nadD |
nicotinic acid mononucleotide adenylyltr... |
220 |
Community Requests |
1K4K
|
56.4% |
Yersinia pestis |
|
|
|
|
|
IDP90919
(show subtarget assignments)
|
8 |
expressed |
No |
YPO2608 |
16122821 |
holA |
DNA polymerase III subunit delta [Yersin... |
344 |
Community Requests |
1JQJ
|
71.5% |
Yersinia pestis |
|
|
|
|
|
IDP90575
(show subtarget assignments)
|
8 |
soluble |
No |
YPO2610 |
16122823 |
leuS |
leucyl-tRNA synthetase [Yersinia pestis ... |
860 |
Community Requests |
1H3N
|
46.7% |
Yersinia pestis |
|
|
|
|
|
IDP05277
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2630 |
16122843 |
glnS |
glutaminyl-tRNA synthetase [Yersinia pes... |
598 |
Phase 5: 2010 |
1O0B
|
80.3% |
Yersinia pestis |
Protein synthesis: tRNA aminoacylation |
|
|
|
|
IDP02339
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2647 |
16122856 |
proV |
glycine betaine/L-proline transport ATP-... |
399 |
Phase 3: June 2008 |
3FVQ
|
25.1% |
Yersinia pestis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00509
(show subtarget assignments)
|
1 |
in_pdb 3RY3 |
No |
YPO2660 |
16122866 |
|
putative solute-binding protein |
525 |
Phase 2: March 2008 |
3RY3
|
100% |
Yersinia pestis |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP00458
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO2680 |
16122885 |
celC |
N,N'-diacetylchitobiose-specific PTS sys... |
115 |
Phase 2: March 2008 |
1WCR
|
67% |
Yersinia pestis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP00556
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2686 |
16122891 |
pgm |
phosphoglucomutase |
547 |
Phase 2: March 2008 |
2FUV
|
82.4% |
Yersinia pestis |
Energy metabolism |
Sugars |
|
|
|
IDP00449
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2706 |
16122910 |
yplA |
phospholipase A |
320 |
Phase 2: March 2008 |
|
|
Yersinia pestis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP90914
(show subtarget assignments)
|
8 |
purified |
No |
YPO2710 |
16122914 |
nadB |
L-aspartate oxidase [Yersinia pestis CO9... |
545 |
Community Requests |
1CHU
|
82% |
Yersinia pestis |
|
|
|
|
|
IDP02465
(show subtarget assignments)
|
1 |
soluble |
No |
YPO2713 |
16122917 |
rseB |
periplasmic negative regulator of sigmaE... |
318 |
Phase 3: June 2008 |
2V42
|
58.8% |
Yersinia pestis |
Regulatory functions |
Other |
|
|
|
IDP00572
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2717 |
16122921 |
lepB |
lsignal peptidase I |
332 |
Phase 2: March 2008 |
1T7D
|
54.8% |
Yersinia pestis |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP00540
(show subtarget assignments)
|
1 |
purified |
No |
YPO2719 |
16122923 |
era |
GTP-binding protein Era |
303 |
Phase 2: March 2008 |
1EGA
|
83.8% |
Yersinia pestis |
Cellular processes |
Cell division |
|
|
|
IDP00202
(show subtarget assignments)
|
1 |
soluble |
No |
YPO2731 |
16122935 |
- |
putative membrane protein |
679 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00529
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2734 |
16122938 |
ccmA |
putative heme exporter protein A |
218 |
Phase 2: March 2008 |
1B0U
|
27.5% |
Yersinia pestis |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP00408
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2735 |
16122939 |
ccmB |
heme exporter protein B |
219 |
Phase 2: March 2008 |
|
|
Yersinia pestis |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP00530
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2736 |
16122940 |
ccmC |
putative heme exporter protein C |
245 |
Phase 2: March 2008 |
|
|
Yersinia pestis |
Cellular processes |
Other |
|
|
|
IDP00531
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2737 |
16122941 |
ccmD |
putative heme exporter protein D |
100 |
Phase 2: March 2008 |
|
|
Yersinia pestis |
Cellular processes |
Other |
|
|
|
IDP00542
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2744 |
16122948 |
fadL |
long-chain fatty acid outer membrane tra... |
423 |
Phase 2: March 2008 |
1T16
|
64% |
Yersinia pestis |
Cell envelope |
Other |
|
|
|
IDP00544
(show subtarget assignments)
|
1 |
purified |
No |
YPO2746 |
16122950 |
fadI |
3-ketoacyl-CoA thiolase |
436 |
Phase 2: March 2008 |
1ULQ
|
37.4% |
Yersinia pestis |
Cellular processes |
Detoxification |
|
|
|
IDP00545
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2747 |
16122951 |
fadJ |
multifunctional fatty acid oxidation com... |
774 |
Phase 2: March 2008 |
1WDK
|
34.1% |
Yersinia pestis |
Cellular processes |
Detoxification |
|
|
|
IDP00539
(show subtarget assignments)
|
1 |
purified |
No |
YPO2751 |
16122955 |
aroC |
chorismate synthase |
361 |
Phase 2: March 2008 |
1R52
|
45% |
Yersinia pestis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00583
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2752 |
16122956 |
mepA |
penicillin-insensitive murein endopeptid... |
275 |
Phase 2: March 2008 |
1TZP
|
67.6% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00577
(show subtarget assignments)
|
1 |
in_pdb 3OYT |
Yes |
YPO2757 |
16122961 |
fabB |
3-oxoacyl-(acyl carrier protein) synthas... |
407 |
Phase 2: March 2008 |
3OYT
|
100% |
Yersinia pestis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP90784
(show subtarget assignments)
|
8 |
in_pdb 3PYZ 3NRS 3N2A 3QCZ |
No |
YPO2769 |
16122973 |
folC |
bifunctional folylpolyglutamate synthase... |
434 |
Community Requests |
3N2A
|
100% |
Yersinia pestis |
|
|
|
|
|
IDP02550
(show subtarget assignments)
|
1 |
in_pdb 3RF0 |
Yes |
YPO2837 |
16123032 |
ppx |
exopolyphosphatase [Yersinia pestis CO92... |
519 |
Phase 3: June 2008 |
1U6Z
|
76.3% |
Yersinia pestis |
Central intermediary metabolism |
Phosphorus compounds |
|
|
|
IDP00220
(show subtarget assignments)
|
1 |
purified |
No |
YPO2855 |
16123048 |
- |
putative protease |
464 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP90816
(show subtarget assignments)
|
8 |
soluble |
No |
YPO2878 |
16123070 |
hisS |
histidyl-tRNA synthetase [Yersinia pesti... |
424 |
Community Requests |
1KMM
|
82.1% |
Yersinia pestis |
|
|
|
|
|
IDP90683
(show subtarget assignments)
|
8 |
purified |
No |
YPO2879 |
16123071 |
ispG |
4-hydroxy-3-methylbut-2-en-1-yl diphosph... |
375 |
Community Requests |
3NOY
|
43.5% |
Yersinia pestis |
|
|
|
|
|
IDP01643
(show subtarget assignments)
|
1 |
crystallized |
No |
YPO2892 |
16123083 |
hscA |
chaperone protein HscA [Yersinia pestis ... |
650 |
Phase 3: June 2008 |
2KHO
|
37.8% |
Yersinia pestis |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP00562
(show subtarget assignments)
|
1 |
purified |
No |
YPO2908 |
16123099 |
hmp |
nitric oxide dioxygenase |
396 |
Phase 2: March 2008 |
1GVH
|
63.1% |
Yersinia pestis |
Energy metabolism |
Electron transport |
|
|
|
IDP90868
(show subtarget assignments)
|
8 |
in_crystallization_trials |
No |
YPO2912 |
16123101 |
nadE |
NAD synthetase [Yersinia pestis CO92] |
540 |
Community Requests |
3N05
|
44.6% |
Yersinia pestis |
|
|
|
|
|
IDP00173
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2922 |
16123109 |
- |
putative membrane protein |
486 |
Phase 1: October 2007 |
3K4U
|
14.4% |
Yersinia pestis |
Unknown function |
General |
|
|
|
IDP02052
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2924 |
16123111 |
|
hypothetical protein YPO2924 [Yersinia p... |
215 |
Phase 3: June 2008 |
|
|
Yersinia pestis |
Cell envelope |
Other |
|
|
|
IDP00407
(show subtarget assignments)
|
1 |
purified |
No |
YPO2929 |
16123116 |
acpS |
4'-phosphopantetheinyl transferase |
126 |
Phase 2: March 2008 |
3H88
|
53.2% |
Yersinia pestis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP00439
(show subtarget assignments)
|
1 |
in_pdb 3F4N |
No |
YPO2930 |
16123117 |
pdxJ |
pyridoxal phosphate biosynthetic protein... |
243 |
Phase 2: March 2008 |
3F4N
|
100% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridoxine |
|
|
|
IDP01648
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2944 |
16123127 |
|
putative pili chaperone protein [Yersini... |
259 |
Phase 3: June 2008 |
3Q48
|
32.8% |
Yersinia pestis |
Cell envelope |
Surface structures |
|
|
|
IDP01651
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2946 |
16123129 |
clpB5 |
Clp ATPase [Yersinia pestis CO92] |
891 |
Phase 3: June 2008 |
1QVR
|
35.5% |
Yersinia pestis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00429
(show subtarget assignments)
|
1 |
purified |
No |
YPO2958 |
16123140 |
sfuA |
iron(III)-binding periplasmic protein |
339 |
Phase 2: March 2008 |
1XVX
|
79.9% |
Yersinia pestis |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00430
(show subtarget assignments)
|
1 |
purified |
No |
YPO2960 |
16123142 |
sfuC |
iron(III)-transport ATP-binding protein ... |
349 |
Phase 2: March 2008 |
3FVQ
|
39.8% |
Yersinia pestis |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00453
(show subtarget assignments)
|
1 |
purified |
No |
YPO2969 |
16123150 |
|
putative iron-sulphur protein |
189 |
Phase 2: March 2008 |
|
|
Yersinia pestis |
Energy metabolism |
Electron transport |
|
|
|
IDP00424
(show subtarget assignments)
|
1 |
purified |
No |
YPO2975 |
16123156 |
|
aminotransferase |
411 |
Phase 2: March 2008 |
2X5D
|
88.6% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Thiamine |
|
|
|
IDP02350
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO2977 |
16123158 |
glk |
glucokinase [Yersinia pestis CO92] |
323 |
Phase 3: June 2008 |
1Q18
|
78.6% |
Yersinia pestis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP90921
(show subtarget assignments)
|
8 |
purified |
No |
YPO2984 |
16123165 |
gltX |
glutamyl-tRNA synthetase [Yersinia pesti... |
471 |
Community Requests |
2CFO
|
38.4% |
Yersinia pestis |
|
|
|
|
|
IDP90632
(show subtarget assignments)
|
8 |
in_crystallization_trials |
No |
YPO2989 |
16123170 |
ligA |
NAD-dependent DNA ligase LigA [Yersinia ... |
670 |
Community Requests |
2OWO
|
78.5% |
Yersinia pestis |
|
|
|
|
|
IDP01665
(show subtarget assignments)
|
1 |
soluble |
No |
YPO3001 |
16123182 |
|
putative pyridine nucleotide-disulphide ... |
548 |
Phase 3: June 2008 |
3ICR
|
58% |
Yersinia pestis |
Cellular processes |
Detoxification |
|
|
|
IDP00177
(show subtarget assignments)
|
1 |
purified |
No |
YPO3007 |
16123186 |
- |
putative membrane protein |
509 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP01671
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3012 |
16123191 |
cysA |
sulfate/thiosulfate transporter subunit ... |
363 |
Phase 3: June 2008 |
1Z47
|
39.4% |
Yersinia pestis |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02174
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3031 |
16123208 |
|
putative acetyltransferase [Yersinia pes... |
141 |
Phase 3: June 2008 |
2PDO
|
78% |
Yersinia pestis |
Central intermediary metabolism |
Other |
|
|
|
IDP00559
(show subtarget assignments)
|
1 |
purified |
No |
YPO3032 |
16123209 |
hemF |
coproporphyrinogen III oxidase |
309 |
Phase 2: March 2008 |
3E8J
|
59.5% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP01669
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3048 |
16123225 |
|
ABC transporter ATP-binding protein [Yer... |
356 |
Phase 3: June 2008 |
1Z47
|
36.8% |
Yersinia pestis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00222
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3049 |
16123226 |
- |
putative binding protein-dependent trans... |
589 |
Phase 1: October 2007 |
3DKN
|
15.3% |
Yersinia pestis |
|
|
|
|
|
IDP00223
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO3054 |
16123231 |
- |
putative carboxypeptidase |
225 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
|
|
|
|
|
IDP00224
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3058 |
16123235 |
- |
putative membrane protein |
288 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Mobile and extrachromosomal element functions |
Transposon functions |
|
|
|
IDP01657
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3061 |
16123238 |
dapX |
lipoprotein [Yersinia pestis CO92] |
352 |
Phase 3: June 2008 |
3TGO
|
56.5% |
Yersinia pestis |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02175
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3064 |
16123241 |
bcp |
thioredoxin-dependent thiol peroxidase [... |
157 |
Phase 3: June 2008 |
3DRN
|
36.9% |
Yersinia pestis |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00225
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3069 |
16123246 |
- |
putative exported protein |
486 |
Phase 1: October 2007 |
3C37
|
15% |
Yersinia pestis |
Purines, pyrimidines, nucleosides, and nucleotides |
2'-Deoxyribonucleotide metabolism |
|
|
|
IDP00581
(show subtarget assignments)
|
1 |
in_pdb 3RDW |
Yes |
YPO3070 |
16123247 |
|
putative arsenate reductase |
118 |
Phase 2: March 2008 |
3RDW
|
100% |
Yersinia pestis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP90916
(show subtarget assignments)
|
8 |
soluble |
No |
YPO3073 |
16123250 |
cysS |
cysteinyl-tRNA synthetase [Yersinia pest... |
461 |
Community Requests |
1LI5
|
83.9% |
Yersinia pestis |
|
|
|
|
|
IDP90900
(show subtarget assignments)
|
8 |
cloned |
No |
YPO3075 |
16123252 |
|
UDP-2,3-diacylglucosamine hydrolase [Yer... |
240 |
Community Requests |
|
|
Yersinia pestis |
|
|
|
|
|
IDP02536
(show subtarget assignments)
|
1 |
in_pdb 3KUU |
No |
YPO3076 |
16123253 |
purE |
phosphoribosylaminoimidazole carboxylase... |
174 |
Phase 3: June 2008 |
3KUU
|
99.4% |
Yersinia pestis |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP00455
(show subtarget assignments)
|
1 |
purified |
No |
YPO3080 |
16123257 |
tesA |
multifunctional acyl-CoA thioesterase I ... |
212 |
Phase 2: March 2008 |
1IVN
|
60.4% |
Yersinia pestis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP90812
(show subtarget assignments)
|
8 |
soluble |
No |
YPO3117 |
16123282 |
hemH |
ferrochelatase [Yersinia pestis CO92] |
320 |
Community Requests |
2QD2
|
26.2% |
Yersinia pestis |
|
|
|
|
|
IDP00480
(show subtarget assignments)
|
1 |
soluble |
No |
YPO3118 |
16123283 |
adk |
adenylate kinase |
214 |
Phase 2: March 2008 |
1AKE
|
87.4% |
Yersinia pestis |
Purines, pyrimidines, nucleosides, and nucleotides |
Nucleotide and nucleoside interconversions |
|
|
|
IDP90891
(show subtarget assignments)
|
8 |
cloned |
No |
YPO3122 |
16123287 |
dnaX |
DNA polymerase III subunits gamma and ta... |
658 |
Community Requests |
1JR3
|
46.7% |
Yersinia pestis |
|
|
|
|
|
IDP90530
(show subtarget assignments)
|
8 |
cloned |
No |
YPO3168 |
16123330 |
cyoE |
protoheme IX farnesyltransferase |
295 |
Community Requests |
|
|
Yersinia pestis |
|
|
|
|
|
IDP90890
(show subtarget assignments)
|
8 |
in_crystallization_trials |
No |
YPO3176 |
16123338 |
ispA |
geranyltranstransferase [Yersinia pestis... |
306 |
Community Requests |
2FOR
|
70.9% |
Yersinia pestis |
|
|
|
|
|
IDP90880
(show subtarget assignments)
|
8 |
purified |
No |
YPO3177 |
16123339 |
dxs |
1-deoxy-D-xylulose-5-phosphate synthase ... |
619 |
Community Requests |
2O1S
|
82.7% |
Yersinia pestis |
|
|
|
|
|
IDP90527
(show subtarget assignments)
|
8 |
cloned |
No |
YPO3179 |
16123341 |
pgpA |
phosphatidylglycerophosphatase A [Yersin... |
161 |
Community Requests |
|
|
Yersinia pestis |
|
|
|
|
|
IDP00521
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO3180 |
16123342 |
thiL |
thiamine monophosphate kinase |
329 |
Phase 2: March 2008 |
3MCQ
|
41.3% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Thiamine |
|
|
|
IDP00402
(show subtarget assignments)
|
1 |
purified |
No |
YPO3182 |
16123344 |
ribH |
riboflavin synthase subunit beta |
156 |
Phase 2: March 2008 |
3MK3
|
82.1% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP90906
(show subtarget assignments)
|
8 |
in_crystallization_trials |
No |
YPO3183 |
16123345 |
ribD |
bifunctional diaminohydroxyphosphoribosy... |
369 |
Community Requests |
2G6V
|
71.8% |
Yersinia pestis |
|
|
|
|
|
IDP02068
(show subtarget assignments)
|
1 |
crystallized |
No |
YPO3194 |
16123356 |
ahpC |
putative alkyl hydroperoxide reductase s... |
200 |
Phase 3: June 2008 |
1ZOF
|
59% |
Yersinia pestis |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02539
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3200 |
16123361 |
malZ |
maltodextrin glucosidase [Yersinia pesti... |
609 |
Phase 3: June 2008 |
1EA9
|
33.5% |
Yersinia pestis |
Energy metabolism |
Biosynthesis and degradation of polysaccharides |
|
|
|
IDP90795
(show subtarget assignments)
|
8 |
cloned |
No |
YPO3244 |
16123403 |
fadE |
acyl-CoA dehydrogenase [Yersinia pestis ... |
815 |
Community Requests |
2UXW
|
18.8% |
Yersinia pestis |
|
|
|
|
|
IDP00227
(show subtarget assignments)
|
1 |
expressed |
No |
YPO3249 |
16123408 |
- |
putative amino acid hydrolase |
430 |
Phase 1: October 2007 |
3N5F
|
36% |
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP90901
(show subtarget assignments)
|
8 |
in_crystallization_trials |
No |
YPO3273 |
16123430 |
pssA |
phosphatidylserine synthase [Yersinia pe... |
452 |
Community Requests |
3HSI
|
50.3% |
Yersinia pestis |
|
|
|
|
|
IDP00461
(show subtarget assignments)
|
1 |
expressed |
No |
YPO3285 |
16123440 |
tyrA |
bifunctional chorismate mutase/prephenat... |
373 |
Phase 2: March 2008 |
2PV7
|
47.2% |
Yersinia pestis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP90826
(show subtarget assignments)
|
8 |
cloned |
No |
YPO3305 |
16123458 |
alaS |
alanyl-tRNA synthetase [Yersinia pestis ... |
875 |
Community Requests |
3HXU
|
45% |
Yersinia pestis |
|
|
|
|
|
IDP90935
(show subtarget assignments)
|
8 |
cloned |
No |
YPO3313 |
16123466 |
|
C-terminal region of transketolase [Yers... |
314 |
Community Requests |
2O1S
|
28.7% |
Yersinia pestis |
|
|
|
|
|
IDP90651
(show subtarget assignments)
|
8 |
expressed |
No |
YPO3314 |
16123467 |
|
putative N-terminal region of transketol... |
276 |
Community Requests |
3OOY
|
34.4% |
Yersinia pestis |
|
|
|
|
|
IDP02559
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3325 |
16123478 |
dmsA |
anaerobic dimethyl sulfoxide reductase c... |
816 |
Phase 3: June 2008 |
1E60
|
28.7% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP01694
(show subtarget assignments)
|
1 |
purified |
No |
YPO3335 |
16123488 |
fumA |
fumarate hydratase, class I [Yersinia pe... |
547 |
Phase 3: June 2008 |
2ISB
|
10.1% |
Yersinia pestis |
Energy metabolism |
TCA cycle |
|
|
|
IDP01699
(show subtarget assignments)
|
1 |
purified |
No |
YPO3343 |
16123493 |
|
extracellular solute-binding protein [Ye... |
256 |
Phase 3: June 2008 |
3KBR
|
34% |
Yersinia pestis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00436
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3358 |
16123508 |
surE |
stationary phase survival protein SurE |
254 |
Phase 2: March 2008 |
2V4N
|
79.9% |
Yersinia pestis |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP01698
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO3359 |
16123509 |
truD |
tRNA pseudouridine synthase D [Yersinia ... |
349 |
Phase 3: June 2008 |
1SB7
|
64.5% |
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00520
(show subtarget assignments)
|
1 |
in_pdb 3F6M 3FPI |
No |
YPO3360 |
16123510 |
ispF |
2-C-methyl-D-erythritol 2,4-cyclodiphosp... |
162 |
Phase 2: March 2008 |
3F6M
|
100% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|