|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene Name |
Common Name |
Sequence Length |
Selection Phase |
Homolog PDB ID |
Homolog Sequence Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP05537
(show subtarget assignments)
|
1 |
cloned |
No |
CD3419 |
126701042 |
hemB |
delta-aminolevulinic acid dehydratase [C... |
321 |
Phase 5: 2010 |
1W5Q
|
55.2% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin |
|
|
|
|
IDP05538
(show subtarget assignments)
|
1 |
cloned |
No |
CD3392 |
126701015 |
|
putative collagen-binding surface protei... |
1014 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Unknown function: General |
|
|
|
|
IDP05536
(show subtarget assignments)
|
1 |
cloned |
No |
CD3145 |
126700762 |
|
putative serine-aspartate-rich surface a... |
1190 |
Phase 5: 2010 |
1YO8
|
7.6% |
Clostridium difficile |
Unknown function: General |
|
|
|
|
IDP05535
(show subtarget assignments)
|
1 |
cloned |
No |
CD3071 |
126700688 |
|
glycosyl hydrolase [Clostridium difficil... |
692 |
Phase 5: 2010 |
2XVG
|
22.3% |
Clostridium difficile |
Unknown function: Enzymes of unknown specificity |
|
|
|
|
IDP05539
(show subtarget assignments)
|
1 |
in_pdb 4E16 |
No |
CD3426 |
126701049 |
cbiF |
precorrin-4 C(11)-methyltransferase [Clo... |
250 |
Phase 5: 2010 |
4E16
|
100% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin |
|
|
|
|
IDP05534
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CD3106 |
126700723 |
|
putative phopho-sugar aldolase [Clostrid... |
213 |
Phase 5: 2010 |
3R8R
|
35.2% |
Clostridium difficile |
Unknown function: General |
|
|
|
|
IDP05322
(show subtarget assignments)
|
1 |
cloned |
No |
CD3430 |
126701053 |
cbiC |
cobalt-precorrin-8X methylmutase [Clostr... |
210 |
Phase 5: 2010 |
2AFR
|
41.9% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin |
|
|
|
|
IDP90167
(show subtarget assignments)
|
8 |
purified |
No |
CD1838 |
123066836 |
|
Shikimate kinase |
177 |
Community Requests |
2PT5
|
31.6% |
Clostridium difficile |
|
|
|
|
|
IDP05353
(show subtarget assignments)
|
1 |
cloned |
No |
CD2903 |
126700520 |
|
putative phage cell wall hydrolase [Clos... |
656 |
Phase 5: 2010 |
3H41
|
8.1% |
Clostridium difficile |
Unknown function: Enzymes of unknown specificity |
|
|
|
|
IDP05072
(show subtarget assignments)
|
1 |
cloned |
No |
CD3564 |
126701190 |
spoIIR |
stage II sporulation protein [Clostridiu... |
198 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Sporulation and germination |
|
|
|
|
IDP05306
(show subtarget assignments)
|
1 |
cloned |
No |
CD2786 |
126700402 |
|
cell surface protein [Clostridium diffic... |
525 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cell envelope: Other |
|
|
|
|
IDP05533
(show subtarget assignments)
|
1 |
cloned |
No |
CD2149 |
126699765 |
|
hypothetical protein CD2149 [Clostridium... |
419 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Unknown function: General |
|
|
|
|
IDP05540
(show subtarget assignments)
|
1 |
cloned |
No |
CD3515 |
126701139 |
glmU |
bifunctional protein [Clostridium diffic... |
459 |
Phase 5: 2010 |
4AAW
|
48.4% |
Clostridium difficile |
Central intermediary metabolism: Amino sugars |
|
|
|
|
IDP05526
(show subtarget assignments)
|
1 |
soluble |
No |
CD1319 |
126698918 |
|
putative polysaccharide deacetylase [Clo... |
247 |
Phase 5: 2010 |
2J13
|
27.1% |
Clostridium difficile |
Energy metabolism: Biosynthesis and degradation of polysaccharides |
|
|
|
|
IDP05527
(show subtarget assignments)
|
1 |
cloned |
No |
CD2600 |
126700220 |
|
putative carbon starvation [Clostridium ... |
473 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Adaptations to atypical conditions |
|
|
|
|
IDP05529
(show subtarget assignments)
|
1 |
cloned |
No |
CD2658 |
126700272 |
mraW |
S-adenosyl-methyltransferase [Clostridiu... |
318 |
Phase 5: 2010 |
1WG8
|
41.2% |
Clostridium difficile |
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
|
IDP05525
(show subtarget assignments)
|
1 |
soluble |
No |
CD2550 |
126700167 |
|
putative sugar transporter, substrate-bi... |
430 |
Phase 5: 2010 |
1EU8
|
25.8% |
Clostridium difficile |
Transport and binding proteins: Amino acids, peptides and amines |
|
|
|
|
IDP05523
(show subtarget assignments)
|
1 |
soluble |
No |
CD2204 |
126699821 |
|
esterase [Clostridium difficile 630] |
260 |
Phase 5: 2010 |
2UZ0
|
33.5% |
Clostridium difficile |
Fatty acid and phospholipid metabolism: Degradation |
|
|
|
|
IDP05292
(show subtarget assignments)
|
1 |
cloned |
No |
CD1600 |
126699204 |
thiK |
hydroxyethylthiazole kinase [Clostridium... |
262 |
Phase 5: 2010 |
3HPD
|
35.5% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine |
|
|
|
|
IDP05522
(show subtarget assignments)
|
1 |
cloned |
No |
CD2240 |
126699857 |
nanA |
N-acetylneuraminate lyase [Clostridium d... |
302 |
Phase 5: 2010 |
1F5Z
|
69.9% |
Clostridium difficile |
Central intermediary metabolism: Amino sugars |
|
|
|
|
IDP05531
(show subtarget assignments)
|
1 |
cloned |
No |
CD2770 |
126700386 |
|
putative capsular polysaccharide biosynt... |
363 |
Phase 5: 2010 |
3C48
|
25.3% |
Clostridium difficile |
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
|
IDP05524
(show subtarget assignments)
|
1 |
cloned |
No |
CD2402 |
126700017 |
|
putative cell wall hydrolase [Clostridiu... |
396 |
Phase 5: 2010 |
3H41
|
20.5% |
Clostridium difficile |
Cellular processes: Sporulation and germination |
|
|
|
|
IDP05528
(show subtarget assignments)
|
1 |
in_pdb 4E1L |
No |
CD2676 |
126700290 |
thlA2 |
putative acetyl-CoA acetyltransferase [C... |
392 |
Phase 5: 2010 |
4E1L
|
100% |
Clostridium difficile |
Cellular processes: Toxin production and resistance |
|
|
|
|
IDP05519
(show subtarget assignments)
|
1 |
cloned |
No |
CD1704 |
126699311 |
thiG |
thiazole synthase [Clostridium difficile... |
261 |
Phase 5: 2010 |
1XM3
|
47.5% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine |
|
|
|
|
IDP05518
(show subtarget assignments)
|
1 |
cloned |
No |
CD1702 |
126699308 |
thiC |
thiamine biosynthesis protein ThiC [Clos... |
438 |
Phase 5: 2010 |
3EPM
|
43.1% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine |
|
|
|
|
IDP05520
(show subtarget assignments)
|
1 |
soluble |
No |
CD1822 |
126699430 |
bcp |
putative thiol peroxidase (bacterioferri... |
154 |
Phase 5: 2010 |
3DRN
|
42.6% |
Clostridium difficile |
Cellular processes: Detoxification |
|
|
|
|
IDP05521
(show subtarget assignments)
|
1 |
cloned |
No |
CD1858 |
126699468 |
|
putative cell surface protein [Clostridi... |
526 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cell envelope: Other |
|
|
|
|
IDP05293
(show subtarget assignments)
|
1 |
cloned |
No |
CD1408 |
126699011 |
ddl |
D-alanine--D-alanine ligase [Clostridium... |
299 |
Phase 5: 2010 |
3R23
|
51.5% |
Clostridium difficile |
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
|
IDP90161
(show subtarget assignments)
|
8 |
purified |
No |
CD1835 |
123174273 |
|
Chorismate synthase (5-enolpyruvylshikim... |
359 |
Community Requests |
1UM0
|
38.7% |
Clostridium difficile |
|
|
|
|
|
IDP05512
(show subtarget assignments)
|
1 |
cloned |
No |
CD1601 |
126699205 |
thiE1 |
thiamine-phosphate pyrophosphorylase [Cl... |
210 |
Phase 5: 2010 |
1XI3
|
41% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine |
|
|
|
|
IDP05513
(show subtarget assignments)
|
1 |
cloned |
No |
CD0278 |
126697850 |
|
putative transcriptional regulator [Clos... |
130 |
Phase 5: 2010 |
4A5M
|
34.6% |
Clostridium difficile |
Regulatory functions: DNA interactions |
|
|
|
|
IDP05514
(show subtarget assignments)
|
1 |
purified |
No |
CD1315 |
126698913 |
ribC |
riboflavin biosynthesis protein [Clostri... |
309 |
Phase 5: 2010 |
1MRZ
|
32.7% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD |
|
|
|
|
IDP05510
(show subtarget assignments)
|
1 |
soluble |
No |
CD1303 |
126698901 |
|
NAD-dependent deacetylase [Clostridium d... |
245 |
Phase 5: 2010 |
1MA3
|
40.8% |
Clostridium difficile |
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
|
IDP05515
(show subtarget assignments)
|
1 |
cloned |
No |
CD1687 |
126699293 |
|
putative lipoprotein [Clostridium diffic... |
278 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cell envelope: Other |
|
|
|
|
IDP05516
(show subtarget assignments)
|
1 |
soluble |
No |
CD1697 |
126699303 |
ribH |
riboflavin synthase beta chain (6,7-dime... |
158 |
Phase 5: 2010 |
1RVV
|
66.5% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD |
|
|
|
|
IDP05504
(show subtarget assignments)
|
1 |
purified |
No |
CD0869 |
126698446 |
modA |
putative molybdenum ABC transporter,subs... |
270 |
Phase 5: 2010 |
1AMF
|
31.9% |
Clostridium difficile |
Transport and binding proteins: Anions |
|
|
|
|
IDP05505
(show subtarget assignments)
|
1 |
cloned |
No |
CD1029 |
126698613 |
|
putative cell wall anchored protein [Clo... |
553 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Regulatory functions: Other |
|
|
|
|
IDP05517
(show subtarget assignments)
|
1 |
soluble |
No |
CD1699 |
126699305 |
ribB |
riboflavin synthase subunit alpha [Clost... |
221 |
Phase 5: 2010 |
1KZL
|
38.5% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD |
|
|
|
|
IDP05290
(show subtarget assignments)
|
1 |
cloned |
No |
CD0488 |
126698065 |
sugE |
quaternary ammonium compound-resistance ... |
106 |
Phase 5: 2010 |
2I68
|
30.2% |
Clostridium difficile |
Cellular processes: Toxin production and resistance |
|
|
|
|
IDP05289
(show subtarget assignments)
|
1 |
soluble |
No |
CD0784 |
126698364 |
|
putative N-acetylmuramoyl-L-alanine amid... |
281 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
|
IDP05506
(show subtarget assignments)
|
1 |
soluble |
No |
CD1232 |
126698828 |
|
putative lipoprotein [Clostridium diffic... |
273 |
Phase 5: 2010 |
1NA0
|
15.8% |
Clostridium difficile |
Unknown function: General |
|
|
|
|
IDP05501
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CD0270 |
126697842 |
fliM |
putative flagellar motor switch protein ... |
293 |
Phase 5: 2010 |
2HP7
|
15.7% |
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05500
(show subtarget assignments)
|
1 |
cloned |
No |
CD0261 |
126697833 |
fliQ |
flagellar export protein [Clostridium di... |
89 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05497
(show subtarget assignments)
|
1 |
cloned |
No |
CD0241 |
126697812 |
|
phosphoserine phosphatase [Clostridium d... |
205 |
Phase 5: 2010 |
1F5S
|
32.1% |
Clostridium difficile |
Amino acid biosynthesis: Serine family |
|
|
|
|
IDP05498
(show subtarget assignments)
|
1 |
cloned |
No |
CD0249 |
126697820 |
fliG |
flagellar motor switch protein [Clostrid... |
356 |
Phase 5: 2010 |
3PKR
|
28.4% |
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05530
(show subtarget assignments)
|
1 |
cloned |
No |
CD1534 |
126699138 |
|
putative gamma-glutamyltranspeptidase [C... |
521 |
Phase 5: 2010 |
2NLZ
|
54.7% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs |
|
|
|
|
IDP90163
(show subtarget assignments)
|
8 |
in_pdb 3JS3 |
No |
CD2217 |
172044608 |
aroD |
3-dehydroquinate dehydratase (3-dehydroq... |
255 |
Community Requests |
3JS3
|
100% |
Clostridium difficile |
|
|
|
|
|
IDP05291
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CD1211 |
126698807 |
|
putative acetyltransferase [Clostridium ... |
163 |
Phase 5: 2010 |
1YX0
|
23.9% |
Clostridium difficile |
Cellular processes: Toxin production and resistance |
|
|
|
|
IDP05288
(show subtarget assignments)
|
1 |
expressed |
No |
CD0252 |
126697823 |
fliJ |
flagellar protein [Clostridium difficile... |
148 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05294
(show subtarget assignments)
|
1 |
cloned |
No |
CD1418 |
126699021 |
|
putative drug/sodium antiporter [Clostri... |
451 |
Phase 5: 2010 |
3MKT
|
20.6% |
Clostridium difficile |
Transport and binding proteins: Other |
|
|
|
|
IDP05495
(show subtarget assignments)
|
1 |
cloned |
No |
CD0237 |
126697808 |
fliD |
flagellar cap protein [Clostridium diffi... |
507 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05502
(show subtarget assignments)
|
1 |
cloned |
No |
CD0386 |
126697956 |
|
putative collagen-binding surface protei... |
1014 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Unknown function: General |
|
|
|
|
IDP05489
(show subtarget assignments)
|
1 |
soluble |
No |
CD0106 |
126697677 |
cwlD |
germination-specific N-acetylmuramoyl-L-... |
250 |
Phase 5: 2010 |
1JWQ
|
25.6% |
Clostridium difficile |
Cellular processes: Sporulation and germination |
|
|
|
|
IDP05285
(show subtarget assignments)
|
1 |
selected |
No |
CD0663 |
126698240 |
tcdA |
toxin A [Clostridium difficile 630] |
2710 |
Phase 5: 2010 |
3SRZ
|
20% |
Clostridium difficile |
Cellular processes: Pathogenesis |
|
|
|
|
IDP05283
(show subtarget assignments)
|
1 |
soluble |
No |
CD0229 |
126697800 |
flgM |
negative regulator of flagellin synthesi... |
91 |
Phase 5: 2010 |
1RP3
|
27.5% |
Clostridium difficile |
Regulatory functions: DNA interactions |
|
|
|
|
IDP05282
(show subtarget assignments)
|
1 |
soluble |
No |
CD0228 |
126697799 |
fliN |
flagellar motor switch protein [Clostrid... |
104 |
Phase 5: 2010 |
1O6A
|
23.1% |
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05279
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CD0254 |
126697825 |
flgD |
putative basal-body rod modification pro... |
202 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05286
(show subtarget assignments)
|
1 |
cloned |
No |
CD0232 |
126697803 |
flgL |
flagellar hook-associated protein [Clost... |
310 |
Phase 5: 2010 |
3PWX
|
17.1% |
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05284
(show subtarget assignments)
|
1 |
expressed |
No |
CD0369 |
126697939 |
|
hypothetical protein CD0369 [Clostridium... |
74 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Hypothetical proteins: Conserved |
|
|
|
|
IDP05280
(show subtarget assignments)
|
1 |
soluble |
No |
CD0279A |
126697852 |
|
hypothetical protein CD0279A [Clostridiu... |
68 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Hypothetical proteins: Conserved |
|
|
|
|
IDP05281
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CD0136 |
126697708 |
|
PTS system, IIB component [Clostridium d... |
108 |
Phase 5: 2010 |
1H9C
|
42.2% |
Clostridium difficile |
Signal transduction: PTS |
|
|
|
|
IDP05493
(show subtarget assignments)
|
1 |
cloned |
No |
CD0231 |
126697802 |
flgK |
putative flagellar hook-associated prote... |
436 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05265
(show subtarget assignments)
|
1 |
purified |
No |
CD3543 |
126701167 |
|
putative nicotinate phosphribosyltransfe... |
476 |
Phase 5: 2010 |
2F7F
|
43.3% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides |
|
|
|
|
IDP05264
(show subtarget assignments)
|
1 |
expressed |
No |
CD3257 |
126700876 |
|
putative polysaccharide deacetylase [Clo... |
275 |
Phase 5: 2010 |
1W17
|
25.5% |
Clostridium difficile |
Energy metabolism: Biosynthesis and degradation of polysaccharides |
|
|
|
|
IDP05261
(show subtarget assignments)
|
1 |
cloned |
No |
CD2772 |
126700388 |
tuaG |
putative teichuronic acid biosynthesis g... |
212 |
Phase 5: 2010 |
3BCV
|
23.6% |
Clostridium difficile |
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
|
IDP05262
(show subtarget assignments)
|
1 |
in_pdb 4EBH 3SRT |
No |
CD0872 |
126698449 |
maa |
maltose O-acetyltransferase [Clostridium... |
185 |
Phase 5: 2010 |
3SRT
|
100% |
Clostridium difficile |
Cellular processes: Detoxification |
|
|
|
|
IDP05260
(show subtarget assignments)
|
1 |
cloned |
No |
CD2791 |
126700407 |
|
cell surface protein (putative S-layer p... |
623 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cell envelope: Other |
|
|
|
|
IDP05494
(show subtarget assignments)
|
1 |
soluble |
No |
CD0234 |
126697805 |
csrA |
carbon storage regulator [Clostridium di... |
70 |
Phase 5: 2010 |
1T3O
|
47.1% |
Clostridium difficile |
Regulatory functions: RNA interactions |
|
|
|
|
IDP05287
(show subtarget assignments)
|
1 |
cloned |
No |
CD0245 |
126697816 |
flgB |
flagellar basal-body rod protein [Clostr... |
97 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05295
(show subtarget assignments)
|
1 |
cloned |
No |
CD1816 |
126699424 |
cmk |
cytidylate kinase [Clostridium difficile... |
216 |
Phase 5: 2010 |
1Q3T
|
44.4% |
Clostridium difficile |
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions |
|
|
|
|
IDP05263
(show subtarget assignments)
|
1 |
cloned |
No |
CD2793 |
126700409 |
slpA |
cell surface protein (S-layer precursor ... |
719 |
Phase 5: 2010 |
3CVZ
|
36.4% |
Clostridium difficile |
Cell envelope: Other |
|
|
|
|
IDP05240
(show subtarget assignments)
|
1 |
expressed |
No |
CD0233 |
126697804 |
|
hypothetical protein CD0233 [Clostridium... |
130 |
Phase 5: 2010 |
2AJ7
|
33.1% |
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05218
(show subtarget assignments)
|
1 |
expressed |
No |
CD3433 |
126701056 |
cbiB |
cobalamin biosynthesis protein [Clostrid... |
323 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin |
|
|
|
|
IDP05253
(show subtarget assignments)
|
1 |
cloned |
No |
CD0259 |
126697831 |
|
putative flagellar protein [Clostridium ... |
107 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05219
(show subtarget assignments)
|
1 |
cloned |
No |
CD3567 |
126701193 |
|
putative cell wall hydrolase [Clostridiu... |
516 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Sporulation and germination |
|
|
|
|
IDP05215
(show subtarget assignments)
|
1 |
cloned |
No |
CD3091 |
126700708 |
treA |
trehalose-6-phosphate hydrolase [Clostri... |
555 |
Phase 5: 2010 |
1UOK
|
50.2% |
Clostridium difficile |
Energy metabolism: Biosynthesis and degradation of polysaccharides |
|
|
|
|
IDP05216
(show subtarget assignments)
|
1 |
cloned |
No |
CD3349 |
126700969 |
bclA3 |
putative exosporium glycoprotein [Clostr... |
657 |
Phase 5: 2010 |
3HQV
|
35.6% |
Clostridium difficile |
Unknown function: General |
|
|
|
|
IDP05214
(show subtarget assignments)
|
1 |
cloned |
No |
CD2796 |
126700412 |
|
cell surface protein [Clostridium diffic... |
626 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cell envelope: Other |
|
|
|
|
IDP05212
(show subtarget assignments)
|
1 |
cloned |
No |
CD2696 |
126700310 |
|
putative aminotransferase [Clostridium d... |
396 |
Phase 5: 2010 |
4DGT
|
43.2% |
Clostridium difficile |
Cellular processes: Pathogenesis |
|
|
|
|
IDP05054
(show subtarget assignments)
|
1 |
cloned |
No |
CD0250 |
126697821 |
fliH |
flagellar assembly protein [Clostridium ... |
243 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05057
(show subtarget assignments)
|
1 |
cloned |
No |
CD0266 |
126697838 |
fliA |
RNA polymerase sigma factor for flagella... |
233 |
Phase 5: 2010 |
1RP3
|
38.2% |
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05056
(show subtarget assignments)
|
1 |
soluble |
No |
CD0257 |
126697829 |
motB |
chemotaxis protein [Clostridium difficil... |
231 |
Phase 5: 2010 |
2K1S
|
20.3% |
Clostridium difficile |
Cellular processes: Chemotaxis and motility |
|
|
|
|
IDP05213
(show subtarget assignments)
|
1 |
soluble |
No |
CD2769 |
126700385 |
|
capsular polysaccharide biosynthesis pro... |
597 |
Phase 5: 2010 |
2GN4
|
17.4% |
Clostridium difficile |
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
|
IDP05217
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CD3421 |
126701044 |
hemC |
porphobilinogen deaminase [Clostridium d... |
301 |
Phase 5: 2010 |
1PDA
|
37.2% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin |
|
|
|
|
IDP05061
(show subtarget assignments)
|
1 |
cloned |
No |
CD1631 |
126699235 |
sodA |
superoxide dismutase (Mn) [Clostridium d... |
234 |
Phase 5: 2010 |
2RCV
|
47% |
Clostridium difficile |
Cellular processes: Detoxification |
|
|
|
|
IDP05062
(show subtarget assignments)
|
1 |
purified |
No |
CD1919 |
126699529 |
|
putative ethanolamine/propanediol utiliz... |
253 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin |
|
|
|
|
IDP05206
(show subtarget assignments)
|
1 |
cloned |
No |
CD2247 |
126699865 |
cspBA |
putative germination-specific protease [... |
1132 |
Phase 5: 2010 |
3I6S
|
10.5% |
Clostridium difficile |
Protein fate: Degradation of proteins, peptides, and glycopeptides |
|
|
|
|
IDP05207
(show subtarget assignments)
|
1 |
cloned |
No |
CD2365 |
126699980 |
|
putative sulfonate ABC transporter,solut... |
363 |
Phase 5: 2010 |
3QSL
|
20.4% |
Clostridium difficile |
Transport and binding proteins: Amino acids, peptides and amines |
|
|
|
|
IDP05208
(show subtarget assignments)
|
1 |
cloned |
No |
CD2373 |
126699988 |
|
putative carbon starvation protein [Clos... |
499 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Adaptations to atypical conditions |
|
|
|
|
IDP05065
(show subtarget assignments)
|
1 |
soluble |
No |
CD2469 |
126700086 |
spoIIP |
putative stage II sporulation protein P ... |
339 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Sporulation and germination |
|
|
|
|
IDP05205
(show subtarget assignments)
|
1 |
cloned |
No |
CD1770 |
126699379 |
ogt2 |
methylated-DNA--protein-cysteine methylt... |
164 |
Phase 5: 2010 |
2G7H
|
32.3% |
Clostridium difficile |
Protein synthesis: tRNA and rRNA base modification |
|
|
|
|
IDP05210
(show subtarget assignments)
|
1 |
cloned |
No |
CD2464 |
126700081 |
hemN |
oxygen-independent coproporphyrinogen II... |
380 |
Phase 5: 2010 |
1OLT
|
20.8% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin |
|
|
|
|
IDP05204
(show subtarget assignments)
|
1 |
expressed |
No |
CD1723 |
126699329 |
|
acyltransferase [Clostridium difficile 6... |
254 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Fatty acid and phospholipid metabolism: Biosynthesis |
|
|
|
|
IDP05201
(show subtarget assignments)
|
1 |
cloned |
No |
CD1698 |
126699304 |
ribA |
riboflavin biosynthesis protein [Clostri... |
408 |
Phase 5: 2010 |
3MGZ
|
25.2% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD |
|
|
|
|
IDP05202
(show subtarget assignments)
|
1 |
cloned |
No |
CD1700 |
126699306 |
ribD |
riboflavin biosynthesis protein [Clostri... |
367 |
Phase 5: 2010 |
2HXV
|
41.4% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD |
|
|
|
|
IDP05211
(show subtarget assignments)
|
1 |
cloned |
No |
CD2574 |
126700193 |
|
putative thiamine pyrophosphokinase [Clo... |
213 |
Phase 5: 2010 |
3IHK
|
28.8% |
Clostridium difficile |
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine |
|
|
|
|
IDP05257
(show subtarget assignments)
|
1 |
crystallized |
No |
CD2748 |
126700363 |
|
putative transferase [Clostridium diffic... |
165 |
Phase 5: 2010 |
2EG0
|
48.2% |
Clostridium difficile |
Cellular processes: Toxin production and resistance |
|
|
|
|
IDP05203
(show subtarget assignments)
|
1 |
cloned |
No |
CD1708 |
126699315 |
|
hypothetical protein CD1708 [Clostridium... |
455 |
Phase 5: 2010 |
|
|
Clostridium difficile |
Cellular processes: Adaptations to atypical conditions |
|
|
|
|
IDP05196
(show subtarget assignments)
|
1 |
cloned |
No |
CD0961 |
126698545 |
|
putative phage cell wall hydrolase [Clos... |
656 |
Phase 5: 2010 |
3H41
|
8.1% |
Clostridium difficile |
Unknown function: Enzymes of unknown specificity |
|
|
|
|
IDP05195
(show subtarget assignments)
|
1 |
soluble |
No |
CD0873 |
126698450 |
|
ABC transporter, substrate-binding lipop... |
340 |
Phase 5: 2010 |
3LKV
|
32.9% |
Clostridium difficile |
Transport and binding proteins: Amino acids, peptides and amines |
|
|
|
|