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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 18 of 60, showing 100 records out of 5973 total, starting on record 1701
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90414
(
show subtarget assignments
)
8
expressed
No
CT_429
3328859
hypothetical protein [Chlamydia trachoma...
329
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90413
(
show subtarget assignments
)
8
cloned
No
CT_622
3329069
CHLPN 76kDa Homolog [Chlamydia trachomat...
647
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90424
(
show subtarget assignments
)
8
cloned
No
CT_546
3328985
predicted OMP [Chlamydia trachomatis D/U...
289
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90419
(
show subtarget assignments
)
8
cloned
No
CT_446
3328878
euo
CHLPS Euo Protein [Chlamydia trachomatis...
183
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90418
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_466
3328900
hypothetical protein [Chlamydia trachoma...
109
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90417
(
show subtarget assignments
)
8
cloned
No
CT_504
3328941
hypothetical protein [Chlamydia trachoma...
288
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90420
(
show subtarget assignments
)
8
cloned
No
CT_465
3328899
hypothetical protein [Chlamydia trachoma...
213
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90423
(
show subtarget assignments
)
8
cloned
No
CT_444
3328876
omcA
9kDa-Cysteine-Rich Lipoprotein [Chlamydi...
88
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90422
(
show subtarget assignments
)
8
cloned
No
CT_471
3328905
hypothetical protein [Chlamydia trachoma...
200
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90421
(
show subtarget assignments
)
8
expressed
No
CT_433
3328864
hypothetical protein [Chlamydia trachoma...
223
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90432
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_865
3329339
hypothetical protein [Chlamydia trachoma...
329
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90427
(
show subtarget assignments
)
8
cloned
No
CT_847
3329319
hypothetical protein [Chlamydia trachoma...
172
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90426
(
show subtarget assignments
)
8
cloned
No
CT_863
3329337
hypothetical protein [Chlamydia trachoma...
482
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90504
(
show subtarget assignments
)
8
purified
No
VC0006
15640038
rnpA
ribonuclease P [Vibrio cholerae O1 biova...
118
Predicted Essential
Community Requests
2LJP
54.2%
Vibrio cholerae
IDP90431
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_845
3329317
hypothetical protein [Chlamydia trachoma...
92
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90428
(
show subtarget assignments
)
8
cloned
No
CT_849
3329321
hypothetical protein [Chlamydia trachoma...
159
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90430
(
show subtarget assignments
)
8
cloned
No
CT_812
3329279
pmpD
Putative Outer Membrane Protein D [Chlam...
1531
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90429
(
show subtarget assignments
)
8
cloned
No
CT_860
3329334
hypothetical protein [Chlamydia trachoma...
493
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90503
(
show subtarget assignments
)
8
purified
No
NP_230169
15642769
DNA primase [Vibrio cholerae O1 biovar e...
587
Predicted Essential
Community Requests
1DD9
30.8%
Vibrio cholerae
IDP90435
(
show subtarget assignments
)
8
cloned
No
CT_871
3329346
pmpG
Putative Outer Membrane Protein G [Chlam...
1013
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90434
(
show subtarget assignments
)
8
cloned
No
CT_870
3329345
pmpF
Putative Outer Membrane Protein F [Chlam...
1034
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90433
(
show subtarget assignments
)
8
cloned
No
CT_848
3329320
hypothetical protein [Chlamydia trachoma...
168
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90436
(
show subtarget assignments
)
8
cloned
No
CT_872
3329347
pmpH
Putative Outer Membrane Protein H [Chlam...
1016
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90502
(
show subtarget assignments
)
8
purified
No
Q9KPA4
22653875
RecName: Full=L-aspartate oxidase; Short...
535
Predicted Essential
Community Requests
1CHU
75.3%
Vibrio cholerae
IDP90501
(
show subtarget assignments
)
8
purified
No
Q9KP66
22257009
RecName: Full=Aspartate carbamoyltransfe...
309
Predicted Essential
Community Requests
2BE7
77.7%
Vibrio cholerae
IDP90437
(
show subtarget assignments
)
8
cloned
No
CT_869
3329344
pmpE
Putative Outer Membrane Protein E [Chlam...
964
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90520
(
show subtarget assignments
)
8
purified
No
Q9KSU7
29611872
RecName: Full=Phosphoserine aminotransfe...
364
Predicted Essential
Community Requests
1BJN
65.9%
Vibrio cholerae
IDP90511
(
show subtarget assignments
)
8
purified
No
Q9KPV6
42560015
RecName: Full=Undecaprenyl pyrophosphate...
250
Predicted Essential
Community Requests
1JP3
56%
Vibrio cholerae
IDP90570
(
show subtarget assignments
)
8
in_pdb
4EHI
No
Cj0953c
15792282
purH
bifunctional phosphoribosylaminoimidazol...
510
Predicted Essential
Community Requests
3ZZM
39.2%
Campylobacter jejuni
IDP90537
(
show subtarget assignments
)
8
purified
No
Q9KL24
21542209
RecName: Full=Dihydroorotase; Short=DHOa...
342
Predicted Essential
Community Requests
1XGE
55%
Vibrio cholerae
IDP90510
(
show subtarget assignments
)
8
soluble
No
Cj1676
15792980
murB
UDP-N-acetylenolpyruvoylglucosamine redu...
258
Predicted Essential
Community Requests
3TX1
32.9%
Campylobacter jejuni
IDP90507
(
show subtarget assignments
)
8
soluble
No
VC2270
15642268
riboflavin synthase subunit alpha [Vibri...
217
Predicted Essential
Community Requests
1KZL
35.5%
Vibrio cholerae
IDP90509
(
show subtarget assignments
)
8
purified
No
Cj0347
15791715
trpF
N-(5'phosphoribosyl)anthranilate isomera...
199
Predicted Essential
Community Requests
1DL3
31.4%
Campylobacter jejuni
IDP90508
(
show subtarget assignments
)
8
purified
No
Cj0767c
15792105
coaD
phosphopantetheine adenylyltransferase [...
158
Predicted Essential
Community Requests
3NV7
53.8%
Campylobacter jejuni
IDP90519
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0383c
15791750
ribH
riboflavin synthase subunit beta [Campyl...
154
Predicted Essential
Community Requests
1HQK
51.9%
Campylobacter jejuni
IDP90514
(
show subtarget assignments
)
8
crystallized
No
Cj0513
15791875
phosphoribosylformylglycinamidine syntha...
81
Predicted Essential
Community Requests
1T4A
46.9%
Campylobacter jejuni
IDP90513
(
show subtarget assignments
)
8
in_pdb
3Q62
Yes
YPO1430
16121709
fabA
3-hydroxydecanoyl-(acyl carrier protein)...
172
Predicted Essential
Community Requests
3Q62
100%
Yersinia pestis
IDP90512
(
show subtarget assignments
)
8
in_crystallization_trials
No
Q9KVL6
21362496
RecName: Full=Diaminopimelate epimerase;...
276
Predicted Essential
Community Requests
1BWZ
73.6%
Vibrio cholerae
IDP90518
(
show subtarget assignments
)
8
purified
No
Cj1404
15792722
hypothetical protein Cj1404 [Campylobact...
181
Predicted Essential
Community Requests
1KAM
30.2%
Campylobacter jejuni
IDP90515
(
show subtarget assignments
)
8
in_pdb
3ULW
No
Cj0884
15792215
rpsO
30S ribosomal protein S15 [Campylobacter...
90
Predicted Essential
Community Requests
3ULW
100%
Campylobacter jejuni
IDP90517
(
show subtarget assignments
)
8
in_pdb
3UGS
No
Cj0824
15792162
uppS
undecaprenyl diphosphate synthase [Campy...
222
Predicted Essential
Community Requests
3UGS
100%
Campylobacter jejuni
IDP90516
(
show subtarget assignments
)
8
expressed
No
Cj0535
15791896
oorD
2-oxoglutarate-acceptor oxidoreductase s...
103
Predicted Essential
Community Requests
1HFE
31.1%
Campylobacter jejuni
IDP90527
(
show subtarget assignments
)
8
cloned
No
YPO3179
16123341
pgpA
phosphatidylglycerophosphatase A [Yersin...
161
Predicted Essential
Community Requests
Yersinia pestis
IDP90522
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO0310
16120648
ubiC
chorismate pyruvate lyase [Yersinia pest...
174
Predicted Essential
Community Requests
1G1B
50.6%
Yersinia pestis
IDP90521
(
show subtarget assignments
)
8
in_pdb
3OAM
No
VC1875
15641877
3-deoxy-manno-octulosonate cytidylyltran...
252
Predicted Essential
Community Requests
3OAM
100%
Vibrio cholerae
IDP90536
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0187c
15791574
purN
phosphoribosylglycinamide formyltransfer...
188
Predicted Essential
Community Requests
1C2T
38.6%
Campylobacter jejuni
IDP90526
(
show subtarget assignments
)
8
crystallized
No
YPO1106
16121406
ppnK
inorganic polyphosphate/ATP-NAD kinase [...
293
Predicted Essential
Community Requests
2AN1
83.6%
Yersinia pestis
IDP90523
(
show subtarget assignments
)
8
in_pdb
3Q12
3Q10
No
YPO3402
16123551
panC
pantoate--beta-alanine ligase [Yersinia ...
284
Predicted Essential
Community Requests
3Q10
100%
Yersinia pestis
IDP90525
(
show subtarget assignments
)
8
in_pdb
3UWQ
3LDV
No
VC1911
15641913
orotidine 5'-phosphate decarboxylase [Vi...
231
Predicted Essential
Community Requests
3LDV
100%
Vibrio cholerae
IDP90524
(
show subtarget assignments
)
8
purified
No
VC1730
15641734
DNA topoisomerase I [Vibrio cholerae O1 ...
876
Predicted Essential
Community Requests
1CY0
48.3%
Vibrio cholerae
IDP90535
(
show subtarget assignments
)
8
soluble
No
VC2695
15642690
rRNA methylase [Vibrio cholerae O1 biova...
158
Predicted Essential
Community Requests
3N4J
58.5%
Vibrio cholerae
IDP90530
(
show subtarget assignments
)
8
cloned
No
YPO3168
16123330
cyoE
protoheme IX farnesyltransferase
295
Predicted Essential
Community Requests
Yersinia pestis
IDP90529
(
show subtarget assignments
)
8
soluble
No
YPO1127
16121427
nicA
quinolinate synthetase
353
Predicted Essential
Community Requests
2QS0
31.7%
Yersinia pestis
IDP90528
(
show subtarget assignments
)
8
cloned
No
VCA1063
15601814
ornithine decarboxylase [Vibrio cholerae...
720
Predicted Essential
Community Requests
1ORD
59.1%
Vibrio cholerae
IDP90531
(
show subtarget assignments
)
8
cloned
No
Q9KSF9
20139940
RecName: Full=Asparaginyl-tRNA synthetas...
466
Predicted Essential
Community Requests
1X54
35.2%
Vibrio cholerae
IDP90534
(
show subtarget assignments
)
8
cloned
No
Cj1071
15792396
ssb
single-strand DNA-binding protein [Campy...
183
Predicted Essential
Community Requests
2VW9
35.5%
Campylobacter jejuni
IDP90533
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0996
15792323
ribA
GTP cyclohydrolase II [Campylobacter jej...
186
Predicted Essential
Community Requests
2BZ0
47.2%
Campylobacter jejuni
IDP90532
(
show subtarget assignments
)
8
soluble
No
VC2391
15642388
dihydrodipicolinate reductase [Vibrio ch...
269
Predicted Essential
Community Requests
1ARZ
63.9%
Vibrio cholerae
IDP90543
(
show subtarget assignments
)
8
cloned
No
VC2182
15642181
ipk
4-diphosphocytidyl-2-C-methyl-D-erythrit...
295
Predicted Essential
Community Requests
1OJ4
58%
Vibrio cholerae
IDP90538
(
show subtarget assignments
)
8
soluble
No
YPO3412
16123561
speD
S-adenosylmethionine decarboxylase [Yers...
264
Predicted Essential
Community Requests
Yersinia pestis
IDP90569
(
show subtarget assignments
)
8
soluble
No
VC0369
15640396
rplI
50S ribosomal protein L9 [Vibrio cholera...
149
Predicted Essential
Community Requests
1P85
76.5%
Vibrio cholerae
IDP90552
(
show subtarget assignments
)
8
soluble
No
YPO0058
16120411
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase...
310
Predicted Essential
Community Requests
1EQ2
82.3%
Yersinia pestis
IDP90542
(
show subtarget assignments
)
8
in_pdb
3PJ9
No
Cj0332c
15791700
ndk
nucleoside diphosphate kinase [Campyloba...
137
Predicted Essential
Community Requests
3PJ9
100%
Campylobacter jejuni
IDP90539
(
show subtarget assignments
)
8
crystallized
No
VC2708
15642702
gmk
guanylate kinase [Vibrio cholerae O1 bio...
229
Predicted Essential
Community Requests
1S96
59.8%
Vibrio cholerae
IDP90541
(
show subtarget assignments
)
8
crystallized
No
VC0297
15640325
3-dehydroquinate dehydratase [Vibrio cho...
150
Predicted Essential
Community Requests
3LWZ
70.7%
Vibrio cholerae
IDP90540
(
show subtarget assignments
)
8
in_pdb
3THA
No
Cj0349
15791717
trpA
tryptophan synthase subunit alpha [Campy...
249
Predicted Essential
Community Requests
3THA
100%
Campylobacter jejuni
IDP90551
(
show subtarget assignments
)
8
diffraction
No
VC0875
15640891
prolyl-tRNA synthetase [Vibrio cholerae ...
571
Predicted Essential
Community Requests
2J3L
45.5%
Vibrio cholerae
IDP90546
(
show subtarget assignments
)
8
in_pdb
3RU6
No
Cj0381c
15791748
pyrF
orotidine 5'-phosphate decarboxylase [Ca...
279
Predicted Essential
Community Requests
3RU6
100%
Campylobacter jejuni
IDP90545
(
show subtarget assignments
)
8
soluble
No
YPO1599
16121867
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
244
Predicted Essential
Community Requests
1I01
86.9%
Yersinia pestis
IDP90544
(
show subtarget assignments
)
8
in_pdb
3Q1H
Yes
YPO0486
16120816
folA
dihydrofolate reductase [Yersinia pestis...
160
Predicted Essential
Community Requests
3Q1H
100%
Yersinia pestis
IDP90547
(
show subtarget assignments
)
8
crystallized
No
Cj1601
15792906
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosy...
243
Predicted Essential
Community Requests
2X30
33.7%
Campylobacter jejuni
IDP90550
(
show subtarget assignments
)
8
purified
No
Cj1594
15792899
rpsD
30S ribosomal protein S4 [Campylobacter ...
208
Predicted Essential
Community Requests
1VS5
50.7%
Campylobacter jejuni
IDP90549
(
show subtarget assignments
)
8
in_pdb
3L92
3L93
No
YPO0053
16120406
coaD
phosphopantetheine adenylyltransferase [...
159
Predicted Essential
Community Requests
3L92
100%
Yersinia pestis
IDP90548
(
show subtarget assignments
)
8
cloned
No
Cj0960c
15792289
rnpA
ribonuclease P protein component [Campyl...
108
Predicted Essential
Community Requests
1A6F
27.9%
Campylobacter jejuni
IDP90559
(
show subtarget assignments
)
8
cloned
No
VC0240
15640270
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase...
314
Predicted Essential
Community Requests
1EQ2
73.9%
Vibrio cholerae
IDP90554
(
show subtarget assignments
)
8
selected
No
NMPDR 243277.1.peg.3911
163
Predicted Essential
Community Requests
1DD8
81%
Vibrio cholerae
IDP90553
(
show subtarget assignments
)
8
soluble
No
VC2458
15642454
pyridoxal phosphate biosynthetic protein...
243
Predicted Essential
Community Requests
1M5W
70.8%
Vibrio cholerae
IDP90568
(
show subtarget assignments
)
8
soluble
No
Cj0536
15791897
oorA
2-oxoglutarate-acceptor oxidoreductase s...
374
Predicted Essential
Community Requests
1YD7
43%
Campylobacter jejuni
IDP90558
(
show subtarget assignments
)
8
purified
No
Cj0912c
15792241
cysM
cysteine synthase A [Campylobacter jejun...
299
Predicted Essential
Community Requests
1O58
52.5%
Campylobacter jejuni
IDP90555
(
show subtarget assignments
)
8
in_pdb
3TZL
3M5W
No
Cj0388
15791755
trpS
tryptophanyl-tRNA synthetase [Campylobac...
319
Predicted Essential
Community Requests
3M5W
100%
Campylobacter jejuni
IDP90557
(
show subtarget assignments
)
8
in_pdb
3U09
3TZK
3TZH
3TZC
3RSH
3OP4
3RRO
No
VC2021
15642023
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
248
Predicted Essential
Community Requests
3OP4
100%
Vibrio cholerae
IDP90556
(
show subtarget assignments
)
8
cloned
No
YPO1056
16121356
lpxA
UDP-N-acetylglucosamine acyltransferase
262
Predicted Essential
Community Requests
1LXA
81.7%
Yersinia pestis
IDP90567
(
show subtarget assignments
)
8
in_pdb
3R2E
No
YPO0648
16120973
folB
bifunctional dihydroneopterin aldolase/d...
119
Predicted Essential
Community Requests
3R2E
100%
Yersinia pestis
IDP90562
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0434
15791801
pgm
phosphoglyceromutase [Campylobacter jeju...
492
Predicted Essential
Community Requests
1EJJ
44%
Campylobacter jejuni
IDP90561
(
show subtarget assignments
)
8
cloned
No
YPO1391
16121671
cmk
cytidylate kinase [Yersinia pestis CO92]...
230
Predicted Essential
Community Requests
1KDO
83%
Yersinia pestis
IDP90560
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO2014
16122257
ipk
4-diphosphocytidyl-2-C-methyl-D-erythrit...
299
Predicted Essential
Community Requests
1OJ4
70.9%
Yersinia pestis
IDP90563
(
show subtarget assignments
)
8
soluble
No
VC0061
15640093
thiamine biosynthesis protein ThiC [Vibr...
645
Predicted Essential
Community Requests
3EPM
65%
Vibrio cholerae
IDP90566
(
show subtarget assignments
)
8
in_pdb
3QBO
No
YPO1389
16121669
serC
phosphoserine aminotransferase [Yersinia...
361
Predicted Essential
Community Requests
3QBO
96.7%
Yersinia pestis
IDP90565
(
show subtarget assignments
)
8
soluble
No
VC0162
15640192
ketol-acid reductoisomerase [Vibrio chol...
494
Predicted Essential
Community Requests
1YRL
75.3%
Vibrio cholerae
IDP90564
(
show subtarget assignments
)
8
in_pdb
3L84
3M34
3M6L
3M7I
No
Cj1645
15792950
tkt
transketolase [Campylobacter jejuni subs...
632
Predicted Essential
Community Requests
3L84
100%
Campylobacter jejuni
IDP90578
(
show subtarget assignments
)
8
expressed
No
YPO3401
16123550
panB
3-methyl-2-oxobutanoate hydroxymethyltra...
266
Predicted Essential
Community Requests
1M3U
75.9%
Yersinia pestis
IDP90576
(
show subtarget assignments
)
8
soluble
No
VC0679
15640698
rpsT
30S ribosomal protein S20 [Vibrio choler...
86
Predicted Essential
Community Requests
1VS5
70.9%
Vibrio cholerae
IDP90580
(
show subtarget assignments
)
8
cloned
No
Cj1091c
15792416
leuS
leucyl-tRNA synthetase [Campylobacter je...
809
Predicted Essential
Community Requests
1H3N
42.1%
Campylobacter jejuni
IDP90579
(
show subtarget assignments
)
8
soluble
No
VC0528
15640550
ispD
2-C-methyl-D-erythritol 4-phosphate cyti...
232
We have identified the methylerythritol phosphate (MEP) pathway enzymes, novel d...
Community Requests
1H3M
53.9%
Vibrio cholerae
IDP90592
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC2389
15642386
carB
carbamoyl phosphate synthase large subun...
1076
Predicted Essential
Community Requests
1BXR
85.6%
Vibrio cholerae
IDP90575
(
show subtarget assignments
)
8
soluble
No
YPO2610
16122823
leuS
leucyl-tRNA synthetase [Yersinia pestis ...
860
Predicted Essential
Community Requests
1H3N
46.7%
Yersinia pestis
IDP90574
(
show subtarget assignments
)
8
in_pdb
3NX3
No
Cj0227
15791599
argD
acetylornithine aminotransferase [Campyl...
395
Predicted Essential
Community Requests
3NX3
100%
Campylobacter jejuni
IDP90573
(
show subtarget assignments
)
8
cloned
No
Cj0479
15791843
rpoC
DNA-directed RNA polymerase beta' chain ...
1517
Predicted Essential
Community Requests
3IYD
46.1%
Campylobacter jejuni
IDP92061
(
show subtarget assignments
)
8
selected
No
TGME49_063490
237832303
ubiquitin-conjugating enzyme E2, putativ...
163
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1JAS
52.8%
Toxoplasma gondii
IDP92060
(
show subtarget assignments
)
8
selected
No
TGME49_063190
237832243
adenylosuccinate lyase, putative [Toxopl...
500
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2PTS
43.2%
Toxoplasma gondii
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