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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 19 of 60, showing 100 records out of 5973 total, starting on record 1801
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP05590
(
show subtarget assignments
)
1
soluble
No
BA_2986
30257575
putative lipoprotein [Bacillus anthracis...
189
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05589
(
show subtarget assignments
)
1
soluble
No
BA_2931
30257523
putative lipoprotein [Bacillus anthracis...
149
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05592
(
show subtarget assignments
)
1
cloned
No
BA_3194
30257761
putative lipoprotein [Bacillus anthracis...
160
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05263
(
show subtarget assignments
)
1
cloned
No
CD2793
126700409
slpA
cell surface protein (S-layer precursor ...
719
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3CVZ
36.4%
Clostridium difficile
Cell envelope: Other
IDP05580
(
show subtarget assignments
)
1
soluble
No
BA_0936
30254679
putative lipoprotein [Bacillus anthracis...
138
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05582
(
show subtarget assignments
)
1
cloned
No
BA_1978
30256633
putative lipoprotein [Bacillus anthracis...
218
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05586
(
show subtarget assignments
)
1
expressed
No
BA_2746
30257351
putative lipoprotein [Bacillus anthracis...
198
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05577
(
show subtarget assignments
)
1
soluble
No
BA_0602
30254206
putative lipoprotein [Bacillus anthracis...
172
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05567
(
show subtarget assignments
)
1
soluble
No
lmo2576
16804614
-
pepdidoglycan bound protein [Listeria mo...
1530
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3KPT
7.5%
Listeria monocytogenes
Cell envelope: Other
IDP05625
(
show subtarget assignments
)
1
soluble
No
CD1348
126698947
putative lipoprotein [Clostridium diffic...
178
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05252
(
show subtarget assignments
)
1
soluble
No
lmo2854
16804891
-
hypothetical protein lmo2854 [Listeria m...
267
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Cell envelope: Other
IDP05588
(
show subtarget assignments
)
1
cloned
No
BA_2883
30257480
putative lipoprotein [Bacillus anthracis...
214
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05555
(
show subtarget assignments
)
1
cloned
No
lmo1413
16803453
-
peptidoglycan binding protein [Listeria ...
439
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2KVZ
6.2%
Listeria monocytogenes
Cell envelope: Other
IDP05554
(
show subtarget assignments
)
1
purified
No
CD3669
126701297
hypothetical protein CD3669 [Clostridium...
191
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05012
(
show subtarget assignments
)
1
cloned
No
BA_5070
30259559
cell wall surface anchor family protein ...
148
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05029
(
show subtarget assignments
)
1
cloned
No
BA_0864
30254614
putative lipoprotein [Bacillus anthracis...
198
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05001
(
show subtarget assignments
)
1
purified
No
BA_1090
30254820
putative lipoprotein [Bacillus anthracis...
142
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05532
(
show subtarget assignments
)
1
soluble
No
CD2784
126700400
cell surface protein [Clostridium diffic...
675
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3NE8
9.6%
Clostridium difficile
Cell envelope: Other
IDP05745
(
show subtarget assignments
)
1
expressed
No
CD2787
126700403
cwp84
cell surface protein (putative cell surf...
803
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1FH0
8.2%
Clostridium difficile
Cell envelope: Other
IDP05006
(
show subtarget assignments
)
1
cloned
No
BA_3083
30257668
putative lipoprotein [Bacillus anthracis...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05521
(
show subtarget assignments
)
1
cloned
No
CD1858
126699468
putative cell surface protein [Clostridi...
526
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05007
(
show subtarget assignments
)
1
cloned
No
BA_3383
30257926
putative lipoprotein [Bacillus anthracis...
236
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05228
(
show subtarget assignments
)
1
soluble
No
lmo0971
16803011
dltD
DltD protein for D-alanine esterificatio...
380
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3BMA
31.6%
Listeria monocytogenes
Cell envelope: Other
IDP05238
(
show subtarget assignments
)
1
cloned
No
lmo1799
16803839
-
peptidoglycan binding protein [Listeria ...
903
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1YO8
10%
Listeria monocytogenes
Cell envelope: Other
IDP05511
(
show subtarget assignments
)
1
soluble
No
BA_5634
30260085
putative lipoprotein [Bacillus anthracis...
196
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05515
(
show subtarget assignments
)
1
cloned
No
CD1687
126699293
putative lipoprotein [Clostridium diffic...
278
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05503
(
show subtarget assignments
)
1
soluble
No
BA_4863
30259362
putative lipoprotein [Bacillus anthracis...
124
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05009
(
show subtarget assignments
)
1
soluble
No
BA_4237
30258740
putative lipoprotein [Bacillus anthracis...
253
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05507
(
show subtarget assignments
)
1
cloned
No
BA_5374
30259847
putative lipoprotein [Bacillus anthracis...
161
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05508
(
show subtarget assignments
)
1
cloned
No
BA_5398
30259871
putative lipoprotein [Bacillus anthracis...
143
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05476
(
show subtarget assignments
)
1
soluble
No
BA_2745
30257350
putative lipoprotein [Bacillus anthracis...
117
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05478
(
show subtarget assignments
)
1
cloned
No
BA_2933
30257525
putative lipoprotein [Bacillus anthracis...
203
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05483
(
show subtarget assignments
)
1
soluble
No
BA_3005
30257593
putative lipoprotein [Bacillus anthracis...
128
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05466
(
show subtarget assignments
)
1
soluble
No
BA_1948
30256606
putative lipoprotein [Bacillus anthracis...
148
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05472
(
show subtarget assignments
)
1
cloned
No
BA_2584
30257206
putative lipoprotein [Bacillus anthracis...
197
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05469
(
show subtarget assignments
)
1
soluble
No
BA_2398
30257029
putative lipoprotein [Bacillus anthracis...
177
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05485
(
show subtarget assignments
)
1
cloned
No
BA_3234
30257796
putative lipoprotein [Bacillus anthracis...
141
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05010
(
show subtarget assignments
)
1
soluble
No
BA_4934
30259430
putative lipoprotein [Bacillus anthracis...
144
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05460
(
show subtarget assignments
)
1
cloned
No
BA_0985
30254723
putative lipoprotein [Bacillus anthracis...
153
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05443
(
show subtarget assignments
)
1
cloned
No
lmo0463
16802507
-
hypothetical protein lmo0463 [Listeria m...
93
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Cell envelope: Other
IDP05451
(
show subtarget assignments
)
1
soluble
No
BA_0580
30254186
putative lipoprotein [Bacillus anthracis...
174
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05437
(
show subtarget assignments
)
1
expressed
No
BA_2898
30257493
putative lipoprotein [Bacillus anthracis...
120
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05454
(
show subtarget assignments
)
1
purified
No
BA_0190
30253697
putative lipoprotein [Bacillus anthracis...
155
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05442
(
show subtarget assignments
)
1
cloned
No
BA_0171
30253680
putative lipoprotein [Bacillus anthracis...
113
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05456
(
show subtarget assignments
)
1
cloned
No
BA_1094
30254824
putative wall-associated protein [Bacill...
2224
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05405
(
show subtarget assignments
)
1
expressed
No
BA_0837
30254426
putative lipoprotein [Bacillus anthracis...
179
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3K0Z
78.2%
Bacillus anthracis
Cell envelope: Other
IDP05421
(
show subtarget assignments
)
1
soluble
No
BAS1418
49184435
-
hypothetical protein BAS1418 [Bacillus a...
237
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05422
(
show subtarget assignments
)
1
soluble
No
BA_1872
30256537
putative lipoprotein [Bacillus anthracis...
126
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05486
(
show subtarget assignments
)
1
soluble
No
BA_4573
30259076
putative lipoprotein [Bacillus anthracis...
155
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP05214
(
show subtarget assignments
)
1
cloned
No
CD2796
126700412
cell surface protein [Clostridium diffic...
626
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP05372
(
show subtarget assignments
)
1
cloned
No
BA_0397
30253932
LPXTG-motif cell wall anchor domain prot...
257
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3GHG
24.9%
Bacillus anthracis
Cell envelope: Other
IDP05426
(
show subtarget assignments
)
1
soluble
No
lmo0610
16802652
-
hypothetical protein lmo0610 [Listeria m...
589
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2OMZ
18.5%
Listeria monocytogenes
Cell envelope: Other
IDP02191
(
show subtarget assignments
)
1
expressed
No
FTT0878c
56707982
msrB
methionine sulfoxide reductase B [Franci...
170
Drug Target
Phase 3: June 2008
1XM0
47.6%
Francisella tularensis
Cell envelopeProtein fate
Surface structuresProtein modification and repair
IDP02344
(
show subtarget assignments
)
1
cloned
No
FTT0356
56707508
htpG
heat shock protein 90 [Francisella tular...
628
Conserved; Drug target functions
Phase 3: June 2008
2IOP
52.4%
Francisella tularensis
Cell envelopeProtein fate
Surface structuresProtein folding and stabilization
IDP02235
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT1105c
56708184
msrA1
bifunctional methionine sulfoxide reduct...
284
Drug Target
Phase 3: June 2008
2GT3
23.2%
Francisella tularensis
Cell envelopeProtein fate
Surface structuresProtein modification and repair
IDP02126
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT1221
56708283
hypothetical protein FTT1221 [Francisell...
88
Drug Target
Phase 3: June 2008
Francisella tularensis
Cell envelopeRegulatory functions,Unknown function
Biosynthesis and degradation of murein sacculus and peptidoglycanOther,General
IDP05178
(
show subtarget assignments
)
1
expressed
No
BA_3332
30257877
putative S-layer protein [Bacillus anthr...
338
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
15.1%
Bacillus anthracis
Cell envelope: Surface structures
IDP05168
(
show subtarget assignments
)
1
cloned
No
BA_1926
30256584
putative S-layer protein [Bacillus anthr...
331
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
17.5%
Bacillus anthracis
Cell envelope: Surface structures
IDP05156
(
show subtarget assignments
)
1
soluble
No
BA_1093
30254823
putative S-layer protein [Bacillus anthr...
344
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
26.2%
Bacillus anthracis
Cell envelope: Surface structures
IDP05155
(
show subtarget assignments
)
1
expressed
No
BA_0885
30254634
sap
S-layer protein Sap [Bacillus anthracis ...
814
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
22.4%
Bacillus anthracis
Cell envelope: Surface structures
IDP05173
(
show subtarget assignments
)
1
expressed
No
BA_2528
30257152
N-acetylmuramoyl-L-alanine amidase, fami...
410
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
23.2%
Bacillus anthracis
Cell envelope: Surface structures
IDP05070
(
show subtarget assignments
)
1
cloned
No
CD3246
126700865
putative surface protein [Clostridium di...
709
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Surface structures
IDP05044
(
show subtarget assignments
)
1
expressed
No
BA_3338
30257881
putative S-layer protein [Bacillus anthr...
360
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
15.6%
Bacillus anthracis
Cell envelope: Surface structures
IDP05030
(
show subtarget assignments
)
1
soluble
No
BA_0898
30254646
N-acetylmuramoyl-L-alanine amidase, fami...
529
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
18.1%
Bacillus anthracis
Cell envelope: Surface structures
IDP05642
(
show subtarget assignments
)
1
cloned
No
CD3294
126700913
putative type IV pilin [Clostridium diff...
116
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Surface structures
IDP05609
(
show subtarget assignments
)
1
expressed
No
BA_5054
30259543
putative S-layer protein [Bacillus anthr...
268
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3PYW
19%
Bacillus anthracis
Cell envelope: Surface structures
IDP05368
(
show subtarget assignments
)
1
soluble
No
BA_3737
30258256
N-acetylmuramoyl-L-alanine amidase, fami...
575
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3HMB
15.7%
Bacillus anthracis
Cell envelope: Surface structures
IDP02672
(
show subtarget assignments
)
1
cloned
No
FTT1602
56708622
hypothetical protein FTT1602 [Francisell...
114
Drug Target
Phase 3: June 2008
Francisella tularensis
Cell envelopeUnknown function
OtherGeneral
IDP00588
(
show subtarget assignments
)
1
purified
No
YPO2077
16122316
minD
cell division inhibitor MinD
270
Conserved Gene / Pathway
Phase 2: March 2008
3Q9L
87.8%
Yersinia pestis
Cellular processes
Cell division
IDP00063
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_4952
30259447
aminoglycoside phosphotransferase family...
263
Virulence
Phase 1: October 2007
3I0O
14.1%
Bacillus anthracis
Cellular processes
Toxin production and resistance
IDP01122
(
show subtarget assignments
)
1
soluble
No
BA_4045
30258552
ftsZ
cell division protein FtsZ
386
Conserved Gene / Pathway
Phase 2: March 2008
2VAM
78.1%
Bacillus anthracis
Cellular processes
Cell division
IDP01119
(
show subtarget assignments
)
1
purified
No
BA_0344
30253882
ahpF
alkyl hydroperoxide reductase, F subunit...
508
Conserved Gene / Pathway
Phase 2: March 2008
1HYU
55.7%
Bacillus anthracis
Cellular processes
Detoxification
IDP02620
(
show subtarget assignments
)
1
cloned
No
lmo0205
16802251
plcB
phospholipase C [Listeria monocytogenes ...
289
Known virulence-Enzyme ; Predicted virulence-Pathogenicity islands; PMID:1143281...
Phase 3: June 2008
1AH7
32.5%
Listeria monocytogenes
Cellular processes
Toxin production and resistance
IDP00126
(
show subtarget assignments
)
1
soluble
No
NT01ST1449
16764525
mviM
putative virulence protein
307
Virulence
Phase 1: October 2007
1TLT
81.4%
Salmonella enterica
Cellular processes
Pathogenesis
IDP01114
(
show subtarget assignments
)
1
soluble
No
BA_4901
38502945
Septation ring formation regulator ezrA
570
Conserved Gene / Pathway
Phase 2: March 2008
Bacillus anthracis
Cellular processes
Cell division
IDP01111
(
show subtarget assignments
)
1
cloned
No
BA_1135
49035527
Major cold shock protein cspA
67
Conserved Gene / Pathway
Phase 2: March 2008
1CSP
73.1%
Bacillus anthracis
Cellular processes
Adaptations to atypical conditions
IDP00581
(
show subtarget assignments
)
1
in_pdb
3RDW
Yes
YPO3070
16123247
putative arsenate reductase
118
Virulence Associated Factor
Phase 2: March 2008
3RDW
100%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP00579
(
show subtarget assignments
)
1
cloned
No
YPO1122
16121422
tolR
colicin uptake protein TolR
142
Conserved Gene / Pathway
Phase 2: March 2008
2JWK
23.9%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP00062
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_4511
50400989
4-hydroxy-3-methylbut-2-enyl diphosphate...
316
Virulence
Phase 1: October 2007
3F7T
35.4%
Bacillus anthracis
Cellular processes
Toxin production and resistance
IDP00031
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_1078
30254808
blaI
penicillinase repressor
132
Virulence
Phase 1: October 2007
1OKR
35.6%
Bacillus anthracis
Cellular processes
Toxin production and resistance
IDP00576
(
show subtarget assignments
)
1
cloned
No
YPO1398
16121678
cspB
cold shock-like protein
69
Virulence Associated Factor
Phase 2: March 2008
3I2Z
50.7%
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP01102
(
show subtarget assignments
)
1
soluble
No
BA_5424
49040749
Cold shock-like protein cspC
65
Essential Gene
Phase 2: March 2008
1C9O
74.2%
Bacillus anthracis
Cellular processes
Adaptations to atypical conditions
IDP01089
(
show subtarget assignments
)
1
soluble
No
STM4533
16767777
tsr
methyl-accepting chemotaxis protein I
553
Conserved Gene / Pathway
Phase 2: March 2008
3ZX6
49.5%
Salmonella enterica
Cellular processes
Chemotaxis and motility
IDP01083
(
show subtarget assignments
)
1
in_pdb
3OPK
No
STM4324
16767573
cutA
divalent-cation tolerance protein CutA
115
Conserved Gene / Pathway
Phase 2: March 2008
3OPK
100%
Salmonella enterica
Cellular processes
Detoxification
IDP00570
(
show subtarget assignments
)
1
expressed
No
YPO2042
16122281
putative oxidoreductase
536
Conserved Gene / Pathway
Phase 2: March 2008
1TLT
34.9%
Yersinia pestis
Cellular processes
Pathogenesis
IDP01081
(
show subtarget assignments
)
1
soluble
No
STM4267
16767517
putative glutathione S-transferase
222
Conserved Gene / Pathway
Phase 2: March 2008
4ECI
28.4%
Salmonella enterica
Cellular processes
Detoxification
IDP00060
(
show subtarget assignments
)
1
in_pdb
3UH9
Yes
BA_4109
46395774
Metallothiol transferase fosB 2 (Fosfomy...
139
Virulence
Phase 1: October 2007
3UH9
100%
Bacillus anthracis
Cellular processes
Toxin production and resistance
IDP01075
(
show subtarget assignments
)
1
cloned
No
STM4106
16767372
katG
hydroperoxidase
726
Essential Gene
Phase 2: March 2008
1MWV
64.3%
Salmonella enterica
Cellular processes
Detoxification
IDP00061
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_4399
30258896
hemolysin A
279
Virulence
Phase 1: October 2007
3HP7
58.4%
Bacillus anthracis
Cellular processes
Toxin production and resistance
IDP00564
(
show subtarget assignments
)
1
selected
No
YPO1403
16121683
mukF
condesin subunit F
440
Conserved Gene / Pathway
Phase 2: March 2008
3EUH
84.8%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP01070
(
show subtarget assignments
)
1
expressed
No
STM3949
16767219
xerC
site-specific tyrosine recombinase XerC ...
300
Drug Target Function
Phase 2: March 2008
1A0P
37.3%
Salmonella enterica
Cellular processes
Cell division
IDP00030
(
show subtarget assignments
)
1
purified
No
BA_0926
30254669
tellurium resistance protein, putative
401
Virulence
Phase 1: October 2007
2KXT
16%
Bacillus anthracis
Cellular processes
Toxin production and resistance
IDP01061
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM3591
16766877
uspA
universal stress protein A
144
Conserved Gene / Pathway
Phase 2: March 2008
1JMV
66.7%
Salmonella enterica
Cellular processes
Adaptations to atypical conditions
IDP00557
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO3382
16123531
gsrA
serine endoprotease
481
Virulence Associated Factor
Phase 2: March 2008
2ZLE
71.9%
Yersinia pestis
Cellular processes
Adaptations to atypical conditions
IDP01055
(
show subtarget assignments
)
1
crystallized
No
STM3371
16766666
maf
Maf-like protein
197
Conserved Gene / Pathway
Phase 2: March 2008
1EX2
43.7%
Salmonella enterica
Cellular processes
Cell division
IDP00006
(
show subtarget assignments
)
1
soluble
No
BA_0672
30254271
immune inhibitor A metalloprotease
799
Virulence/Drug Target Homolog
Phase 1: October 2007
Bacillus anthracis
Cellular processes
Toxin production and resistance
IDP01047
(
show subtarget assignments
)
1
cloned
No
STM3152
16766452
putative methyl-accepting chemotaxis pro...
547
Conserved Gene / Pathway
Phase 2: March 2008
3ZX6
34.7%
Salmonella enterica
Cellular processes
Chemotaxis and motility
IDP01046
(
show subtarget assignments
)
1
expressed
No
STM3138
16766438
putative methyl-accepting chemotaxis pro...
352
Conserved Gene / Pathway
Phase 2: March 2008
1QU7
16.8%
Salmonella enterica
Cellular processes
Other
IDP00059
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_4013
30258522
fibronectin/fibrinogen-binding protein, ...
569
Virulence
Phase 1: October 2007
3DOA
22.5%
Bacillus anthracis
Cellular processes
Pathogenesis
IDP02569
(
show subtarget assignments
)
1
cloned
No
lmo0264
16802310
inlE
internalin E [Listeria monocytogenes EGD...
499
Known virulence-Invasion; Predicted virulence-Invasion; PMID:11432815 ; Predicte...
Phase 3: June 2008
1H6U
44.9%
Listeria monocytogenes
Cellular processes
Pathogenesis
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