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Targets
Filter Targets:
Selection Phase:
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Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 19 of 60, showing 100 records out of 5973 total, starting on record 1801
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90580
(
show subtarget assignments
)
8
cloned
No
Cj1091c
15792416
leuS
leucyl-tRNA synthetase [Campylobacter je...
809
Predicted Essential
Community Requests
1H3N
42.1%
Campylobacter jejuni
IDP90579
(
show subtarget assignments
)
8
soluble
No
VC0528
15640550
ispD
2-C-methyl-D-erythritol 4-phosphate cyti...
232
We have identified the methylerythritol phosphate (MEP) pathway enzymes, novel d...
Community Requests
1H3M
53.9%
Vibrio cholerae
IDP90585
(
show subtarget assignments
)
8
purified
No
Cj0949c
15792278
peptidyl-arginine deiminase family prote...
325
Predicted Essential
Community Requests
3HVM
45.8%
Campylobacter jejuni
IDP90582
(
show subtarget assignments
)
8
soluble
No
Cj1686c
15792989
topA
DNA topoisomerase I [Campylobacter jejun...
700
Predicted Essential
Community Requests
2GAI
38.6%
Campylobacter jejuni
IDP90584
(
show subtarget assignments
)
8
purified
No
VC0095
15640127
chorismate--pyruvate lyase [Vibrio chole...
183
Predicted Essential
Community Requests
1FW9
28.4%
Vibrio cholerae
IDP90583
(
show subtarget assignments
)
8
soluble
No
Cj1243
15792567
hemE
uroporphyrinogen decarboxylase [Campylob...
340
Predicted Essential
Community Requests
3CYV
45.2%
Campylobacter jejuni
IDP90594
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO0644
16120969
dnaG
DNA primase [Yersinia pestis CO92]
582
Predicted Essential
Community Requests
1DD9
45.7%
Yersinia pestis
IDP90589
(
show subtarget assignments
)
8
soluble
No
VC0296
15640324
acetyl-CoA carboxylase [Vibrio cholerae ...
196
Predicted Essential
Community Requests
1A6X
37.2%
Vibrio cholerae
IDP90588
(
show subtarget assignments
)
8
cloned
No
Q9KLX5
23821639
RecName: Full=GTP cyclohydrolase 1; AltN...
217
Predicted Essential
Community Requests
1FBX
70.5%
Vibrio cholerae
IDP90604
(
show subtarget assignments
)
8
in_pdb
3Q0I
No
VC0045
15640077
fmt
methionyl-tRNA formyltransferase [Vibrio...
315
Predicted Essential
Community Requests
3Q0I
100%
Vibrio cholerae
IDP90593
(
show subtarget assignments
)
8
soluble
No
YPO1522
16121795
metG
methionyl-tRNA synthetase [Yersinia pest...
675
Predicted Essential
Community Requests
1F4L
69.6%
Yersinia pestis
IDP90590
(
show subtarget assignments
)
8
cloned
No
Cj0770c
15792108
lipoprotein, NLPA family [Campylobacter ...
258
Predicted Essential
Community Requests
1P99
35.7%
Campylobacter jejuni
IDP90592
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC2389
15642386
carB
carbamoyl phosphate synthase large subun...
1076
Predicted Essential
Community Requests
1BXR
85.6%
Vibrio cholerae
IDP90591
(
show subtarget assignments
)
8
in_pdb
3N9I
No
YPO0157
16120500
trpS
tryptophanyl-tRNA synthetase [Yersinia p...
346
Predicted Essential
Community Requests
3N9I
100%
Yersinia pestis
IDP90603
(
show subtarget assignments
)
8
selected
No
VC0015
15640047
gyrB
DNA gyrase subunit B [Vibrio cholerae O1...
805
Predicted Essential
Community Requests
1EI1
39.6%
Vibrio cholerae
IDP90597
(
show subtarget assignments
)
8
soluble
No
VC0319
15640346
biotin--protein ligase [Vibrio cholerae ...
320
Predicted Essential
Community Requests
1BIA
54.7%
Vibrio cholerae
IDP90596
(
show subtarget assignments
)
8
cloned
No
Cj1234
15792558
glyS
glycyl-tRNA synthetase subunit beta [Cam...
664
Predicted Essential
Community Requests
Campylobacter jejuni
IDP90595
(
show subtarget assignments
)
8
expressed
No
YPO2298
16122522
phoA
alkaline phosphatase [Yersinia pestis CO...
481
Predicted Essential
Community Requests
1B8J
70.7%
Yersinia pestis
IDP90598
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO3443
16123591
valS
valyl-tRNA synthetase [Yersinia pestis C...
965
Predicted Essential
Community Requests
1GAX
40.5%
Yersinia pestis
IDP90601
(
show subtarget assignments
)
0
work_stopped
No
YPO0643
16120968
rpoD
RNA polymerase sigma factor RpoD [Yersin...
612
Predicted Essential
Community Requests
3IYD
92%
Yersinia pestis
IDP90600
(
show subtarget assignments
)
8
cloned
No
VC0190
15640220
uvrD
DNA-dependent helicase II [Vibrio choler...
723
Predicted Essential
Community Requests
2IS1
66.8%
Vibrio cholerae
IDP90599
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0460
15791824
nusA
transcription elongation factor NusA [Ca...
362
Predicted Essential
Community Requests
1HH2
33.4%
Campylobacter jejuni
IDP90611
(
show subtarget assignments
)
8
in_pdb
3N2I
3LV8
Yes
VC2016
15642018
tmk
thymidylate kinase [Vibrio cholerae O1 b...
212
Predicted Essential
Community Requests
3LV8
100%
Vibrio cholerae
IDP90606
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC0563
15640585
trmD
tRNA (guanine-N(1)-)-methyltransferase [...
247
Predicted Essential
Community Requests
1P9P
78.1%
Vibrio cholerae
IDP90636
(
show subtarget assignments
)
8
purified
No
Cj0432c
15791799
murD
UDP-N-acetylmuramoyl-L-alanyl-D-glutamat...
402
Predicted Essential
Community Requests
1E0D
27.6%
Campylobacter jejuni
IDP90620
(
show subtarget assignments
)
8
expressed
No
VC0275
15640304
phosphoribosylamine--glycine ligase [Vib...
429
Predicted Essential
Community Requests
1GSO
77.9%
Vibrio cholerae
IDP90610
(
show subtarget assignments
)
8
soluble
No
YPO4071
16124184
glyS
glycyl-tRNA synthetase subunit beta [Yer...
689
Predicted Essential
Community Requests
Yersinia pestis
IDP90607
(
show subtarget assignments
)
8
purified
No
VC2015
15642017
DNA polymerase III subunit delta' [Vibri...
324
Predicted Essential
Community Requests
1A5T
33%
Vibrio cholerae
IDP90609
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC1972
15641974
O-succinylbenzoate synthase [Vibrio chol...
332
Predicted Essential
Community Requests
1FHU
54.2%
Vibrio cholerae
IDP90608
(
show subtarget assignments
)
8
in_pdb
3R7T
No
Cj1498c
15792813
purA
adenylosuccinate synthetase [Campylobact...
416
Predicted Essential
Community Requests
3R7T
100%
Campylobacter jejuni
IDP90619
(
show subtarget assignments
)
8
soluble
No
Cj1701c
15793004
rpsC
30S ribosomal protein S3 [Campylobacter ...
233
Predicted Essential
Community Requests
1VS5
56.7%
Campylobacter jejuni
IDP90614
(
show subtarget assignments
)
8
crystallized
No
VC0013
15640045
DNA polymerase III subunit beta [Vibrio ...
366
Predicted Essential
Community Requests
1MMI
63.9%
Vibrio cholerae
IDP90613
(
show subtarget assignments
)
8
soluble
No
Cj0828c
15792166
ilvA
threonine dehydratase [Campylobacter jej...
403
Predicted Essential
Community Requests
1TDJ
32.8%
Campylobacter jejuni
IDP90612
(
show subtarget assignments
)
8
soluble
No
NMPDR 243277.1.peg.3916
281
Predicted Essential
Community Requests
1COZ
17.1%
Vibrio cholerae
IDP90615
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC0626
15640646
glutamate-1-semialdehyde aminotransferas...
432
Predicted Essential
Community Requests
4E77
72%
Vibrio cholerae
IDP90618
(
show subtarget assignments
)
8
purified
No
Cj0314
15791682
lysA
diaminopimelate decarboxylase [Campyloba...
402
Predicted Essential
Community Requests
2QGH
60.2%
Campylobacter jejuni
IDP90617
(
show subtarget assignments
)
8
crystallized
No
YPO3927
16124057
argC
N-acetyl-gamma-glutamyl-phosphate reduct...
334
Predicted Essential
Community Requests
2G17
78.1%
Yersinia pestis
IDP90616
(
show subtarget assignments
)
8
selected
No
VC1054
15641067
DNA polymerase III subunits gamma and ta...
692
Predicted Essential
Community Requests
1JR3
34.5%
Vibrio cholerae
IDP90626
(
show subtarget assignments
)
8
in_pdb
3TI2
3NVS
No
VC1732
15641736
3-phosphoshikimate 1-carboxyvinyltransfe...
426
Predicted Essential
Community Requests
3NVS
100%
Vibrio cholerae
IDP90621
(
show subtarget assignments
)
8
soluble
No
Cj0931c
15792260
argH
argininosuccinate lyase [Campylobacter j...
460
Predicted Essential
Community Requests
1AUW
44.8%
Campylobacter jejuni
IDP90635
(
show subtarget assignments
)
8
crystallized
No
VC1483
15641492
3-hydroxydecanoyl-(acyl carrier protein)...
172
Predicted Essential
Community Requests
1MKA
77.9%
Vibrio cholerae
IDP92558
(
show subtarget assignments
)
8
selected
No
CAA87463
1065719
aadB
aminoglycoside adenylyltransferase [Esch...
177
drug resistance /
This enzyme is one of the most clinically widespread aminogylcoside-deactivating...
Community Requests
Escherichia coli
IDP90625
(
show subtarget assignments
)
8
soluble
No
YPO3758
16123895
coaA
pantothenate kinase [Yersinia pestis CO9...
316
Predicted Essential
Community Requests
1ESM
85.8%
Yersinia pestis
IDP90622
(
show subtarget assignments
)
0
work_stopped
No
YPO3746
16123883
rpoC
DNA-directed RNA polymerase subunit beta...
1406
Predicted Essential
Community Requests
3IYD
92.7%
Yersinia pestis
IDP90624
(
show subtarget assignments
)
8
cloned
No
Cj0718
15792067
dnaE
DNA polymerase III subunit alpha [Campyl...
1200
Predicted Essential
Community Requests
2HPI
37%
Campylobacter jejuni
IDP90623
(
show subtarget assignments
)
8
purified
No
Cj1177c
15792501
gmk
guanylate kinase [Campylobacter jejuni s...
207
Predicted Essential
Community Requests
1S96
39.1%
Campylobacter jejuni
IDP90634
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO3403
16123552
panD
aspartate alpha-decarboxylase [Yersinia ...
126
Predicted Essential
Community Requests
1PPY
78.6%
Yersinia pestis
IDP90629
(
show subtarget assignments
)
8
cloned
No
Cj0896c
15792226
pheT
phenylalanyl-tRNA synthetase subunit bet...
773
Predicted Essential
Community Requests
2RHS
28.6%
Campylobacter jejuni
IDP90628
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC0760
15640779
hisS
histidyl-tRNA synthetase [Vibrio cholera...
422
Predicted Essential
Community Requests
1KMM
74.5%
Vibrio cholerae
IDP90627
(
show subtarget assignments
)
8
selected
No
VC1239
15641252
cobU
adenosylcobinamide kinase/adenosylcobina...
179
Predicted Essential
Community Requests
1C9K
41.3%
Vibrio cholerae
IDP90630
(
show subtarget assignments
)
8
soluble
No
Cj0640c
15792000
aspS
aspartyl-tRNA synthetase [Campylobacter ...
583
Predicted Essential
Community Requests
1C0A
51.8%
Campylobacter jejuni
IDP90633
(
show subtarget assignments
)
8
cloned
No
VC1971
15641973
O-succinylbenzoic acid--CoA ligase [Vibr...
476
Predicted Essential
Community Requests
2QVX
27.9%
Vibrio cholerae
IDP90632
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO2989
16123170
ligA
NAD-dependent DNA ligase LigA [Yersinia ...
670
Predicted Essential
Community Requests
2OWO
78.5%
Yersinia pestis
IDP90631
(
show subtarget assignments
)
8
expressed
No
YPO2526
16122745
acyl-CoA thioester hydrolase YfbB [Yersi...
272
Predicted Essential
Community Requests
1R3D
42.3%
Yersinia pestis
IDP90651
(
show subtarget assignments
)
8
expressed
No
YPO3314
16123467
putative N-terminal region of transketol...
276
Predicted Essential
Community Requests
3OOY
34.4%
Yersinia pestis
IDP90642
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0585
15791945
folP
dihydropteroate synthase [Campylobacter ...
380
Predicted Essential
Community Requests
1AJ0
25.8%
Campylobacter jejuni
IDP90682
(
show subtarget assignments
)
8
in_pdb
3N0L
No
Cj0402
15791769
glyA
serine hydroxymethyltransferase [Campylo...
414
Predicted Essential
Community Requests
3N0L
100%
Campylobacter jejuni
IDP90667
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj1535c
15792843
pgi
glucose-6-phosphate isomerase [Campyloba...
406
Predicted Essential
Community Requests
1ZZG
30.3%
Campylobacter jejuni
IDP90641
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0099
15791487
birA
biotin--protein ligase [Campylobacter je...
217
Predicted Essential
Community Requests
2EAY
27.2%
Campylobacter jejuni
IDP90638
(
show subtarget assignments
)
8
soluble
No
VC1040
15641053
cob(I)yrinic acid a,c-diamide adenosyltr...
201
Predicted Essential
Community Requests
1G5R
64.2%
Vibrio cholerae
IDP90640
(
show subtarget assignments
)
8
cloned
No
Cj0798c
15792136
ddl
D-alanyl-alanine synthetase A [Campyloba...
346
Predicted Essential
Community Requests
2PVP
54%
Campylobacter jejuni
IDP90639
(
show subtarget assignments
)
8
cloned
No
Cj0771c
15792109
lipoprotein, NLPA family [Campylobacter ...
256
Predicted Essential
Community Requests
3TQW
39.8%
Campylobacter jejuni
IDP90650
(
show subtarget assignments
)
8
expressed
No
Cj0713
15792062
trmD
tRNA (guanine-N(1)-)-methyltransferase [...
234
Predicted Essential
Community Requests
3KY7
38%
Campylobacter jejuni
IDP90645
(
show subtarget assignments
)
8
in_pdb
3TSN
No
Cj1239
15792563
pdxA
4-hydroxythreonine-4-phosphate dehydroge...
364
Predicted Essential
Community Requests
3TSN
100%
Campylobacter jejuni
IDP90644
(
show subtarget assignments
)
8
in_crystallization_trials
No
STM1201
16764556
holB
DNA polymerase III subunit delta' [Salmo...
334
Predicted Essential
Community Requests
1A5T
79%
Salmonella enterica
IDP90643
(
show subtarget assignments
)
8
soluble
No
VC0638
15640658
dihydropteroate synthase [Vibrio cholera...
278
Predicted Essential
Community Requests
1AJ0
55.8%
Vibrio cholerae
IDP90649
(
show subtarget assignments
)
8
cloned
No
Cj1104
15792429
4-diphosphocytidyl-2-C-methyl-D-erythrit...
255
Predicted Essential
Community Requests
2V2Q
29%
Campylobacter jejuni
IDP90646
(
show subtarget assignments
)
8
in_pdb
3NXK
No
Cj0029
15791428
ansA
L-asparaginase [Campylobacter jejuni sub...
331
Predicted Essential
Community Requests
3NXK
100%
Campylobacter jejuni
IDP90648
(
show subtarget assignments
)
8
purified
No
VC1219
15641232
pheS
phenylalanyl-tRNA synthetase subunit alp...
327
Predicted Essential
Community Requests
3PCO
76.5%
Vibrio cholerae
IDP90647
(
show subtarget assignments
)
8
cloned
No
VC2685
15642680
metF
5,10-methylenetetrahydrofolate reductase...
304
Predicted Essential
Community Requests
1ZP3
75.3%
Vibrio cholerae
IDP90658
(
show subtarget assignments
)
8
cloned
No
VC2503
15642499
valS
valyl-tRNA synthetase [Vibrio cholerae O...
953
Predicted Essential
Community Requests
1GAX
38.8%
Vibrio cholerae
IDP90653
(
show subtarget assignments
)
8
soluble
No
VC2524
15642520
3-deoxy-D-manno-octulosonate 8-phosphate...
185
Predicted Essential
Community Requests
3N07
99.5%
Vibrio cholerae
IDP90652
(
show subtarget assignments
)
8
expressed
No
Cj0897c
15792227
pheS
phenylalanyl-tRNA synthetase subunit alp...
330
Predicted Essential
Community Requests
3PCO
50.6%
Campylobacter jejuni
IDP90666
(
show subtarget assignments
)
8
purified
No
VC2242
15642240
mesJ protein [Vibrio cholerae O1 biovar ...
440
Predicted Essential
Community Requests
1NI5
44.1%
Vibrio cholerae
IDP90657
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO0556
16120884
murC
UDP-N-acetylmuramate--L-alanine ligase [...
491
Predicted Essential
Community Requests
2F00
86.2%
Yersinia pestis
IDP90654
(
show subtarget assignments
)
8
expressed
No
YPO0474
16120803
ribF
bifunctional riboflavin kinase/FMN adeny...
312
Predicted Essential
Community Requests
1MRZ
32.1%
Yersinia pestis
IDP90656
(
show subtarget assignments
)
8
purified
No
Cj0384c
15791751
kdsA
2-dehydro-3-deoxyphosphooctonate aldolas...
271
Predicted Essential
Community Requests
1FWN
55.7%
Campylobacter jejuni
IDP90655
(
show subtarget assignments
)
8
expressed
No
Cj1346c
15792669
dxr
1-deoxy-D-xylulose 5-phosphate reductois...
356
Predicted Essential
Community Requests
1R0K
36.2%
Campylobacter jejuni
IDP90665
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC2618
15642613
argD
bifunctional N-succinyldiaminopimelate-a...
403
Predicted Essential
Community Requests
2PB0
58.1%
Vibrio cholerae
IDP90661
(
show subtarget assignments
)
8
in_crystallization_trials
No
Q9KSL9
33301117
RecName: Full=Nicotinate-nucleotide--dim...
341
Predicted Essential
Community Requests
1J33
45.2%
Vibrio cholerae
IDP90660
(
show subtarget assignments
)
8
cloned
No
Cj1476c
15792791
pyruvate ferredoxin/flavodoxin oxidoredu...
1186
Predicted Essential
Community Requests
1B0P
53.7%
Campylobacter jejuni
IDP90659
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0822
15792160
dfp
bifunctional phosphopantothenoylcysteine...
384
Predicted Essential
Community Requests
1E20
17.2%
Campylobacter jejuni
IDP90662
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj1288c
15792611
gltX
glutamyl-tRNA synthetase [Campylobacter ...
463
Predicted Essential
Community Requests
2CFO
38.9%
Campylobacter jejuni
IDP90664
(
show subtarget assignments
)
8
cloned
No
Cj0024
15791423
nrdA
ribonucleotide-diphosphate reductase sub...
789
Predicted Essential
Community Requests
3HNC
33.7%
Campylobacter jejuni
IDP90663
(
show subtarget assignments
)
8
soluble
No
VC2157
15642156
dapA
dihydrodipicolinate synthase [Vibrio cho...
292
Predicted Essential
Community Requests
3G0S
59.6%
Vibrio cholerae
IDP02115
(
show subtarget assignments
)
1
purified
No
FTT0900
56708001
hypothetical protein FTT0900 [Francisell...
123
Drug Target
Community Requests
2GM2
22.8%
Francisella tularensis
Cell envelope
Other
IDP90674
(
show subtarget assignments
)
8
cloned
No
Cj0542
15791903
hemA
glutamyl-tRNA reductase [Campylobacter j...
432
Predicted Essential
Community Requests
1GPJ
27.3%
Campylobacter jejuni
IDP90668
(
show subtarget assignments
)
8
purified
No
Cj0206
15791593
thrS
threonyl-tRNA synthetase [Campylobacter ...
602
Predicted Essential
Community Requests
1QF6
43%
Campylobacter jejuni
IDP90681
(
show subtarget assignments
)
8
purified
No
STM3210
16766510
dnaG
DNA primase [Salmonella typhimurium LT2]...
581
Predicted Essential
Community Requests
1DD9
46.1%
Salmonella enterica
IDP90680
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj1401c
15792719
tpiA
triosephosphate isomerase [Campylobacter...
223
Predicted Essential
Community Requests
2JGQ
48.2%
Campylobacter jejuni
IDP90673
(
show subtarget assignments
)
8
expressed
No
VC1833
15641835
quinolinate synthetase [Vibrio cholerae ...
353
Predicted Essential
Community Requests
1WZU
30.6%
Vibrio cholerae
IDP90669
(
show subtarget assignments
)
8
in_pdb
3PAJ
Yes
VC2422
15642419
quinolinate phosphoribosyltransferase [V...
296
Predicted Essential
Community Requests
3PAJ
100%
Vibrio cholerae
IDP90671
(
show subtarget assignments
)
8
in_pdb
3O6C
3O6D
Yes
Cj1238
15792562
pdxJ
pyridoxal phosphate biosynthetic protein...
257
Predicted Essential
Community Requests
3O6C
100%
Campylobacter jejuni
IDP90670
(
show subtarget assignments
)
8
soluble
No
Cj1202
15792526
metF
5,10-methylenetetrahydrofolate reductase...
282
Predicted Essential
Community Requests
1V93
34%
Campylobacter jejuni
IDP90679
(
show subtarget assignments
)
8
cloned
No
Cj0506
15791868
alaS
alanyl-tRNA synthetase [Campylobacter je...
842
Predicted Essential
Community Requests
3HXU
28.5%
Campylobacter jejuni
IDP90677
(
show subtarget assignments
)
8
crystallized
No
Cj0702
15792051
purE
phosphoribosylaminoimidazole carboxylase...
164
Predicted Essential
Community Requests
3TRH
53.7%
Campylobacter jejuni
IDP90676
(
show subtarget assignments
)
8
expressed
No
Cj0533
15791894
sucC
succinyl-CoA synthase, beta subunit [Cam...
387
Predicted Essential
Community Requests
1CQI
45.5%
Campylobacter jejuni
IDP90675
(
show subtarget assignments
)
8
cloned
No
YPO3861
16123996
rffH
glucose-1-phosphate thymidylyltransferas...
293
Predicted Essential
Community Requests
1MC3
86.7%
Yersinia pestis
IDP92563
(
show subtarget assignments
)
8
selected
No
3E90_B
221046696
Chain B, West Nile Vi Rus Ns2b-Ns3protea...
198
potential drug target /
We have identified a number of small molecule inhibitor to West Nile and/or deng...
Community Requests
3E90
100%
West Nile
IDP92561
(
show subtarget assignments
)
8
selected
No
3EQV_A
209870568
Chain A, Crystal Structure Of Penicillin...
542
potential drug target /
Pptase, FactorXa, HCV NS3/NS4A, Trypsin and Elastase/Subtilisin (see below)] and...
Community Requests
3EQV
99.8%
Neisseria gonorrhoeae
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