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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP00416
(
show subtarget assignments
)
1
expressed
No
YPO1212
16121503
2Fe-2S ferredoxin YfaE
85
Conserved Gene / Pathway
Phase 2: March 2008
3AV8
33.3%
Yersinia pestis
Energy metabolism
Electron transport
IDP02600
(
show subtarget assignments
)
1
expressed
No
STM2279
16765606
yfaE
2Fe-2S ferredoxin YfaE [Salmonella typhi...
84
Conserved; Drug target functions
Phase 3: June 2008
1IUE
37.2%
Salmonella enterica
Unknown function
General
IDP91265
(
show subtarget assignments
)
8
cloned
No
NT05BA1551
49178367
2-heptaprenyl-1,4-naphthoquinone methylt...
237
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1VE3
24.9%
Bacillus anthracis
Unclassified: Role category not yet assigned
IDP90724
(
show subtarget assignments
)
8
expressed
No
Cj1719c
15793022
leuA
2-isopropylmalate synthase [Campylobacte...
511
Predicted Essential
Community Requests
3RMJ
37.6%
Campylobacter jejuni
IDP04173
(
show subtarget assignments
)
1
expressed
No
VC2490
15642486
2-isopropylmalate synthase [Vibrio chole...
516
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3RMJ
39%
Vibrio cholerae
Amino acid biosynthesis
Pyruvate family
IDP04713
(
show subtarget assignments
)
1
purified
No
YPO0533
218927730
leuA
2-isopropylmalate synthase [Yersinia pes...
520
conserved gene; putative drug target function;
Phase 4: April 2009
3RMJ
36.3%
Yersinia pestis
Amino acid biosynthesis
Pyruvate family
IDP91378
(
show subtarget assignments
)
8
cloned
No
VV1_1552
27364921
2-octaprenyl-6-methoxyphenyl hydroxylase...
391
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
2X3N
21.2%
Vibrio vulnificus
IDP90879
(
show subtarget assignments
)
8
expressed
No
YPO0909
16121214
ubiH
2-octaprenyl-6-methoxyphenyl hydroxylase...
392
Predicted Essential
Community Requests
2X3N
24.2%
Yersinia pestis
IDP90568
(
show subtarget assignments
)
8
soluble
No
Cj0536
15791897
oorA
2-oxoglutarate-acceptor oxidoreductase s...
374
Predicted Essential
Community Requests
1YD7
43%
Campylobacter jejuni
IDP90516
(
show subtarget assignments
)
8
expressed
No
Cj0535
15791896
oorD
2-oxoglutarate-acceptor oxidoreductase s...
103
Predicted Essential
Community Requests
1HFE
31.1%
Campylobacter jejuni
IDP04395
(
show subtarget assignments
)
1
cloned
No
FTT0076
56707255
sucA
2-oxoglutarate dehydrogenase E1 componen...
941
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
2JGD
47.8%
Francisella tularensis
IDP00744
(
show subtarget assignments
)
1
soluble
No
SACOL1563
57284661
lpdA
2-oxoisovalerate dehydrogenase, E3 compo...
473
Drug Target Function
Phase 2: March 2008
3URH
37%
Staphylococcus aureus
Energy metabolism
Amino acids and amines
IDP02507
(
show subtarget assignments
)
1
cloned
No
FTT1298
56708357
ubiB
2-polyprenylphenol 6-hydroxylase [Franci...
552
Conserved; Drug target functions
Phase 3: June 2008
Francisella tularensis
Biosynthesis of cofactors, prosthetic groups, and carriers
Menaquinone and ubiquinone
IDP01637
(
show subtarget assignments
)
1
crystallized
No
GBAA5111
47530413
menD
2-succinyl-6-hydroxy-2,4-cyclohexadiene-...
584
Conserved; Drug target functions
Phase 3: June 2008
2X7J
46.2%
Bacillus anthracis
Biosynthesis of cofactors, prosthetic groups, and carriers
Menaquinone and ubiquinone
IDP90830
(
show subtarget assignments
)
8
expressed
No
YPO2527
16122746
menD
2-succinyl-6-hydroxy-2,4-cyclohexadiene-...
567
Predicted Essential
Community Requests
2JLA
69%
Yersinia pestis
IDP04028
(
show subtarget assignments
)
1
purified
No
BAS0109
49183143
30S ribosomal protein S10 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1P6G
61.8%
Bacillus anthracis
IDP04590
(
show subtarget assignments
)
1
expressed
No
BAS0136
49183170
30S ribosomal protein S11 [Bacillus anth...
129
Proposed to be essential proteins
Phase 4: April 2009
1VS5
65.9%
Bacillus anthracis
IDP04706
(
show subtarget assignments
)
1
expressed
No
BAS0105
49183139
30S ribosomal protein S12 [Bacillus anth...
140
Proposed to be essential proteins
Phase 4: April 2009
2F4V
71.4%
Bacillus anthracis
IDP90505
(
show subtarget assignments
)
8
soluble
No
YPO0231
16120569
rpsM
30S ribosomal protein S13
118
Predicted Essential
Community Requests
1VS5
85.6%
Yersinia pestis
IDP04589
(
show subtarget assignments
)
1
expressed
No
BAS0135
49183169
30S ribosomal protein S13 [Bacillus anth...
121
Proposed to be essential proteins
Phase 4: April 2009
1FJG
63.9%
Bacillus anthracis
IDP04080
(
show subtarget assignments
)
1
cloned
No
BAS0123
49183157
30S ribosomal protein S14 [Bacillus anth...
61
Proposed to be essential proteins
Phase 4: April 2009
1FJG
73.8%
Bacillus anthracis
IDP90515
(
show subtarget assignments
)
8
in_pdb
3ULW
No
Cj0884
15792215
rpsO
30S ribosomal protein S15 [Campylobacter...
90
Predicted Essential
Community Requests
3ULW
100%
Campylobacter jejuni
IDP04021
(
show subtarget assignments
)
1
expressed
No
BAS3695
49186694
30S ribosomal protein S16 [Bacillus anth...
90
Proposed to be essential proteins
Phase 4: April 2009
1EMW
42.2%
Bacillus anthracis
IDP04663
(
show subtarget assignments
)
1
cloned
No
BAS5325
49188309
30S ribosomal protein S18 [Bacillus anth...
77
Proposed to be essential proteins
Phase 4: April 2009
1P6G
50.6%
Bacillus anthracis
IDP04708
(
show subtarget assignments
)
1
purified
No
BAS0114
49183148
30S ribosomal protein S19 [Bacillus anth...
92
Proposed to be essential proteins
Phase 4: April 2009
1FJG
66.3%
Bacillus anthracis
IDP90576
(
show subtarget assignments
)
8
soluble
No
VC0679
15640698
rpsT
30S ribosomal protein S20 [Vibrio choler...
86
Predicted Essential
Community Requests
1VS5
70.9%
Vibrio cholerae
IDP04604
(
show subtarget assignments
)
1
cloned
No
BAS3678
49186677
30S ribosomal protein S2 [Bacillus anthr...
233
Proposed to be essential proteins
Phase 4: April 2009
1FJG
56.2%
Bacillus anthracis
IDP04585
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS0116
49183150
30S ribosomal protein S3 [Bacillus anthr...
219
Proposed to be essential proteins
Phase 4: April 2009
1VS5
54.3%
Bacillus anthracis
IDP90619
(
show subtarget assignments
)
8
soluble
No
Cj1701c
15793004
rpsC
30S ribosomal protein S3 [Campylobacter ...
233
Predicted Essential
Community Requests
1VS5
56.7%
Campylobacter jejuni
IDP90550
(
show subtarget assignments
)
8
purified
No
Cj1594
15792899
rpsD
30S ribosomal protein S4 [Campylobacter ...
208
Predicted Essential
Community Requests
1VS5
50.7%
Campylobacter jejuni
IDP04064
(
show subtarget assignments
)
1
expressed
No
BAS0127
49183161
30S ribosomal protein S5 [Bacillus anthr...
166
Proposed to be essential proteins
Phase 4: April 2009
1PKP
75.3%
Bacillus anthracis
IDP04069
(
show subtarget assignments
)
1
in_pdb
3R3T
Yes
BAS5327
49188311
30S ribosomal protein S6 [Bacillus anthr...
96
Proposed to be essential proteins
Phase 4: April 2009
3R3T
100%
Bacillus anthracis
IDP04106
(
show subtarget assignments
)
1
cloned
No
BAS0124
49183158
30S ribosomal protein S8 [Bacillus anthr...
132
Proposed to be essential proteins
Phase 4: April 2009
1SEI
85.6%
Bacillus anthracis
IDP04593
(
show subtarget assignments
)
1
cloned
No
BAS0144
49183178
30S ribosomal protein S9 [Bacillus anthr...
130
Proposed to be essential proteins
Phase 4: April 2009
1VS5
55.4%
Bacillus anthracis
IDP02027
(
show subtarget assignments
)
1
soluble
No
CBU_0599
29541200
cysQ-1
3'(2'),5'-bisphosphate nucleotidase [Cox...
271
Conserved; Drug target functions
Phase 3: June 2008
3B8B
39.5%
Coxiella burnetii
Central intermediary metabolism
Sulfur metabolism
IDP00479
(
show subtarget assignments
)
1
in_pdb
3H07
No
YPO0658
16120983
ribB
3,4-dihydroxy-2-butanone 4-phosphate syn...
217
Conserved Gene / Pathway
Phase 2: March 2008
3H07
100%
Yersinia pestis
Biosynthesis of cofactors, prosthetic groups, and carriers
Riboflavin, FMN, and FAD
IDP01450
(
show subtarget assignments
)
1
in_crystallization_trials
No
VC2269
15642267
3,4-dihydroxy-2-butanone 4-phosphate syn...
369
Drug Target Function
Phase 2: March 2008
1G57
30.1%
Vibrio cholerae
Biosynthesis of cofactors, prosthetic groups, and carriers
Riboflavin, FMN, and FAD
IDP91541
(
show subtarget assignments
)
8
selected
No
TGME49_118680
237841017
3',5'--cyclic-nucleotide phosphodiestera...
812
potential drug target /
Phosphodiesterases are key regulators of cell signalling pathways and are attrac...
Community Requests
3QI3
13.8%
Toxoplasma gondii
IDP91542
(
show subtarget assignments
)
8
selected
No
TGME49_080410
237844275
3',5'-cyclic phosphodiesterase, putative...
1085
potential drug target /
Phosphodiesterases are key regulators of cell signalling pathways and are attrac...
Community Requests
1SO2
11.2%
Toxoplasma gondii
IDP90163
(
show subtarget assignments
)
8
in_pdb
3JS3
No
CD2217
172044608
aroD
3-dehydroquinate dehydratase (3-dehydroq...
255
Potential drug target. Shikimate pathway enzyme
Community Requests
3JS3
100%
Clostridium difficile
IDP02836
(
show subtarget assignments
)
1
crystallized
No
GBAA4423
47529716
aroQ
3-dehydroquinate dehydratase [Bacillus a...
146
Conserved; Drug target functions
Phase 3: June 2008
1GQO
57.5%
Bacillus anthracis
Amino acid biosynthesis
Aromatic amino acid family
IDP91207
(
show subtarget assignments
)
8
soluble
No
BT_2842
29348251
3-dehydroquinate dehydratase [Bacteroide...
140
potential drug target /
Shikimate pathway enzyme
Community Requests
2C4W
49%
Bacteroides thetaiotaomicron
IDP91202
(
show subtarget assignments
)
8
in_pdb
3U80
No
BLD_0610
189439473
aroQ
3-dehydroquinate dehydratase [Bifidobact...
148
potential drug target /
Shikimate pathway enzyme
Community Requests
3U80
100%
Bifidobacterium longum
IDP90922
(
show subtarget assignments
)
8
in_pdb
3S42
3L2I
3LB0
3M7W
3O1N
3OEX
3NNT
Yes
STM1358
16764709
aroD
3-dehydroquinate dehydratase [Salmonella...
252
Predicted Essential
Community Requests
3L2I
100%
Salmonella enterica
IDP90829
(
show subtarget assignments
)
8
selected
No
S1855
30063207
aroD
3-dehydroquinate dehydratase [Shigella f...
252
Predicted Essential
Community Requests
3L2I
80.2%
Shigella flexneri
IDP90541
(
show subtarget assignments
)
8
crystallized
No
VC0297
15640325
3-dehydroquinate dehydratase [Vibrio cho...
150
Predicted Essential
Community Requests
3LWZ
70.7%
Vibrio cholerae
IDP90771
(
show subtarget assignments
)
8
in_pdb
3LWZ
No
YPO3660
16123803
aroQ
3-dehydroquinate dehydratase [Yersinia p...
150
Predicted Essential
Community Requests
3LWZ
100%
Yersinia pestis
IDP90162
(
show subtarget assignments
)
8
purified
No
CD1833
123174272
3-dehydroquinate synthase
354
Potential drug target. Shikimate pathway enzyme
Community Requests
3OKF
40.1%
Clostridium difficile
IDP00009
(
show subtarget assignments
)
1
soluble
No
BA_1538
38372188
3-dehydroquinate synthase
363
Drug Target Homolog
Phase 1: October 2007
1XAG
38.3%
Bacillus anthracis
Amino acid biosynthesis
Aromatic amino acid family
IDP01058
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM3486
16766774
aroB
3-dehydroquinate synthase
362
Conserved Gene / Pathway
Phase 2: March 2008
3OKF
62.4%
Salmonella enterica
Amino acid biosynthesis
Aromatic amino acid family
IDP91205
(
show subtarget assignments
)
8
soluble
No
BT_3975
29349383
3-dehydroquinate synthase [Bacteroides t...
353
potential drug target /
Shikimate pathway enzyme
Community Requests
3CLH
34.3%
Bacteroides thetaiotaomicron
IDP90782
(
show subtarget assignments
)
8
soluble
No
Cj1008c
15792335
aroB
3-dehydroquinate synthase [Campylobacter...
351
Predicted Essential
Community Requests
3CLH
51%
Campylobacter jejuni
IDP02604
(
show subtarget assignments
)
1
expressed
No
CBU_1893
29542450
aroB
3-dehydroquinate synthase [Coxiella burn...
360
Conserved; Drug target functions
Phase 3: June 2008
3OKF
48.6%
Coxiella burnetii
Amino acid biosynthesis
Aromatic amino acid family
IDP02414
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT1154c
56708225
aroB
3-dehydroquinate synthase [Francisella t...
359
Conserved; Drug target functions
Phase 3: June 2008
3OKF
44.3%
Francisella tularensis
Amino acid biosynthesis
Aromatic amino acid family
IDP04176
(
show subtarget assignments
)
1
in_pdb
3OKF
No
VC2628
15642623
aroB
3-dehydroquinate synthase [Vibrio choler...
366
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3OKF
100%
Vibrio cholerae
Amino acid biosynthesis
Aromatic amino acid family
IDP02435
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO0152
16120495
aroB
3-dehydroquinate synthase [Yersinia pest...
362
Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...
Phase 3: June 2008
3OKF
63.3%
Yersinia pestis
Amino acid biosynthesis
Aromatic amino acid family
IDP90709
(
show subtarget assignments
)
8
cloned
No
YPO1215
16121506
ubiG
3-demethylubiquinone-9 3-methyltransfera...
242
Predicted Essential
Community Requests
3JWH
20.7%
Yersinia pestis
IDP90653
(
show subtarget assignments
)
8
soluble
No
VC2524
15642520
3-deoxy-D-manno-octulosonate 8-phosphate...
185
Predicted Essential
Community Requests
3N07
99.5%
Vibrio cholerae
IDP02274
(
show subtarget assignments
)
1
in_pdb
3IJ5
Yes
YPO3578
16123722
3-deoxy-D-manno-octulosonate 8-phosphate...
187
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...
Phase 3: June 2008
3IJ5
100%
Yersinia pestis
Hypothetical proteins
Conserved
IDP91097
(
show subtarget assignments
)
0
work_stopped
No
CBU_0479
29541085
kdsB
3-deoxy-D-manno-octulosonate cytidylyltr...
253
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3TQD
100%
Coxiella burnetii
IDP91088
(
show subtarget assignments
)
8
cloned
No
BMA_2275
52429282
kdsB
3-deoxy-D-manno-octulosonate cytidylyltr...
263
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3K8D
52.1%
Burkholderia mallei
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP90803
(
show subtarget assignments
)
8
selected
No
YPO0055
16120408
kdtA
3-deoxy-D-manno-octulosonic-acid transfe...
425
Predicted Essential
Community Requests
2XCI
25.2%
Yersinia pestis
IDP00947
(
show subtarget assignments
)
1
purified
No
STM0988
16764348
kdsB
3-deoxy-manno-octulosonate cytidylyltran...
248
Essential Gene
Phase 2: March 2008
1VH1
94%
Salmonella enterica
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP91095
(
show subtarget assignments
)
8
in_pdb
3POL
No
A1S_1557
193077192
3-deoxy-manno-octulosonate cytidylyltran...
253
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
3POL
100%
Acinetobacter baumannii
IDP91094
(
show subtarget assignments
)
8
cloned
No
APL_0085
126096365
kdsB
3-deoxy-manno-octulosonate cytidylyltran...
250
potential drug target /
KDO is an essential component of the lipopolysaccharide (LPS) layer. Cells defec...
Community Requests
1VH3
70.6%
Actinobacillus pleuropneumoniae
IDP00066
(
show subtarget assignments
)
1
expressed
No
NTL01CJ00766
6968259
kdsB
3-deoxy-manno-octulosonate cytidylyltran...
239
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
2Y6P
40.2%
Campylobacter jejuni
Protein synthesis
tRNA aminoacylation
IDP02441
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT1478c
56708518
kdsB
3-deoxy-manno-octulosonate cytidylyltran...
250
Drug Target
Phase 3: June 2008
3TQD
51.2%
Francisella tularensis
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP90521
(
show subtarget assignments
)
8
in_pdb
3OAM
No
VC1875
15641877
3-deoxy-manno-octulosonate cytidylyltran...
252
Predicted Essential
Community Requests
3OAM
100%
Vibrio cholerae
IDP02355
(
show subtarget assignments
)
1
in_pdb
3JTJ
Yes
YPO1400
16121680
kdsB
3-deoxy-manno-octulosonate cytidylyltran...
250
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...
Phase 3: June 2008
3JTJ
100%
Yersinia pestis
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP04187
(
show subtarget assignments
)
1
expressed
No
VCA0723
15601479
3-hydroxy-3-methylglutaryl CoA reductase...
436
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1DQ8
35.5%
Vibrio cholerae
Biosynthesis of cofactors, prosthetic groups, and carriers
Other
IDP02583
(
show subtarget assignments
)
1
soluble
No
GBAA5249
47530554
3-hydroxyacyl-CoA dehydrogenase/enoyl-Co...
793
Conserved; Drug target functions
Phase 3: June 2008
1WDK
14.6%
Bacillus anthracis
Fatty acid and phospholipid metabolism
Degradation
IDP02727
(
show subtarget assignments
)
1
crystallized
No
GBAA4249
47778264
3-hydroxybutyrate dehydrogenase [Bacillu...
258
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
3V2H
42.6%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP05101
(
show subtarget assignments
)
1
in_crystallization_trials
No
CD1058
126698642
hbd
3-hydroxybutyryl-CoA dehydrogenase [Clos...
281
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1F0Y
43.9%
Clostridium difficile
Fatty acid and phospholipid metabolism: Degradation
IDP90513
(
show subtarget assignments
)
8
in_pdb
3Q62
Yes
YPO1430
16121709
fabA
3-hydroxydecanoyl-(acyl carrier protein)...
172
Predicted Essential
Community Requests
3Q62
100%
Yersinia pestis
IDP90635
(
show subtarget assignments
)
8
crystallized
No
VC1483
15641492
3-hydroxydecanoyl-(acyl carrier protein)...
172
Predicted Essential
Community Requests
1MKA
77.9%
Vibrio cholerae
IDP01915
(
show subtarget assignments
)
1
cloned
No
GBAA1421
47777930
leuB
3-isopropylmalate dehydrogenase [Bacillu...
354
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
3U1H
60.3%
Bacillus anthracis
Amino acid biosynthesis
Pyruvate family
IDP01791
(
show subtarget assignments
)
1
in_pdb
3UDU
3UDO
Yes
Cj1718c
15793021
leuB
3-isopropylmalate dehydrogenase [Campylo...
358
Possible Vaccine Candidate; Predicted Essential-Modeling
Phase 3: June 2008
3UDO
99.7%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP04444
(
show subtarget assignments
)
1
soluble
No
YPO0532
115346340
leuB
3-isopropylmalate dehydrogenase [Yersini...
365
conserved gene; putative drug target function;
Phase 4: April 2009
1CM7
85.5%
Yersinia pestis
Amino acid biosynthesis
Pyruvate family
IDP91297
(
show subtarget assignments
)
8
cloned
No
STM1195
16764550
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
244
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1I01
95.9%
Salmonella enterica
IDP02782
(
show subtarget assignments
)
0
work_stopped
No
GBAA4874
161611196
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
252
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
3I4F
94.8%
Bacillus anthracis
Fatty acid and phospholipid metabolism
Biosynthesis
IDP02456
(
show subtarget assignments
)
1
crystallized
No
GBAA3921
47529213
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
237
Conserved; Essential;
Phase 3: June 2008
2P68
38.1%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP02370
(
show subtarget assignments
)
1
in_crystallization_trials
No
GBAA1958
47527254
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
242
Conserved; Essential; Involved in sporulation;
Phase 3: June 2008
3OEC
40.9%
Bacillus anthracis
Unknown function
Enzymes of unknown specificity
IDP91245
(
show subtarget assignments
)
8
soluble
No
HP0561
2313678
3-ketoacyl-acyl carrier protein reductas...
247
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3F9I
45.7%
Helicobacter pylori
Fatty acid and phospholipid metabolism: Biosynthesis
IDP91290
(
show subtarget assignments
)
8
soluble
No
SPA1656
56413819
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
244
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1I01
95.9%
Salmonella enterica
IDP90557
(
show subtarget assignments
)
8
in_pdb
3U09
3TZK
3TZH
3TZC
3RSH
3OP4
3RRO
No
VC2021
15642023
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
248
Predicted Essential
Community Requests
3OP4
100%
Vibrio cholerae
IDP90545
(
show subtarget assignments
)
8
soluble
No
YPO1599
16121867
fabG
3-ketoacyl-(acyl-carrier-protein) reduct...
244
Predicted Essential
Community Requests
1I01
86.9%
Yersinia pestis
IDP00544
(
show subtarget assignments
)
1
purified
No
YPO2746
16122950
fadI
3-ketoacyl-CoA thiolase
436
Virulence Associated Factor
Phase 2: March 2008
1ULQ
37.4%
Yersinia pestis
Cellular processes
Detoxification
IDP00415
(
show subtarget assignments
)
1
expressed
No
YPO3767
16123903
fadA
3-ketoacyl-CoA thiolase
387
Virulence Associated Factor
Phase 2: March 2008
3GOA
79.8%
Yersinia pestis
Cellular processes
Detoxification
IDP01000
(
show subtarget assignments
)
1
expressed
No
STM2389
16765716
fadI
3-ketoacyl-CoA thiolase
436
Conserved Gene / Pathway
Phase 2: March 2008
1ULQ
35.8%
Salmonella enterica
Fatty acid and phospholipid metabolism
Degradation
IDP01071
(
show subtarget assignments
)
1
in_pdb
3GOA
Yes
STM3982
16767252
fadA
3-ketoacyl-CoA thiolase
387
Conserved Gene / Pathway
Phase 2: March 2008
3GOA
100%
Salmonella enterica
Fatty acid and phospholipid metabolism
Degradation
IDP01486
(
show subtarget assignments
)
1
in_pdb
3IEB
3JR2
No
VCA0242
15601010
ulaD
3-keto-L-gulonate-6-phosphate decarboxyl...
215
Conserved Gene / Pathway
Phase 2: March 2008
3IEB
100%
Vibrio cholerae
Energy metabolism
Sugars
IDP01008
(
show subtarget assignments
)
1
soluble
No
STM2533
16765853
sseA
3-mercaptopyruvate sulfurtransferase
280
Conserved Gene / Pathway
Phase 2: March 2008
1URH
79.6%
Salmonella enterica
Cellular processes
Detoxification
IDP02745
(
show subtarget assignments
)
1
cloned
No
GBAA4384
47529679
bfmbAa
3-methyl-2-oxobutanoate dehydrogenase, a...
333
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1UM9
41.7%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP02743
(
show subtarget assignments
)
1
cloned
No
GBAA4383
47529678
bfmbAb
3-methyl-2-oxobutanoate dehydrogenase, b...
327
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1UM9
52.9%
Bacillus anthracis
Energy metabolism
Amino acids and amines
IDP02674
(
show subtarget assignments
)
1
purified
No
GBAA1562
47777948
panB
3-methyl-2-oxobutanoate hydroxymethyltra...
279
Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1M3U
43%
Bacillus anthracis
Biosynthesis of cofactors, prosthetic groups, and carriers
Pantothenate and coenzyme A
IDP02089
(
show subtarget assignments
)
1
cloned
No
CBU_0424
29541033
panB
3-methyl-2-oxobutanoate hydroxymethyltra...
266
Conserved; Drug target functions
Phase 3: June 2008
1OY0
42.5%
Coxiella burnetii
Biosynthesis of cofactors, prosthetic groups, and carriers
Pantothenate and coenzyme A
IDP02773
(
show subtarget assignments
)
1
crystallized
No
FTT1389
56708438
panB
3-methyl-2-oxobutanoate hydroxymethyltra...
264
Conserved; Drug target functions
Phase 3: June 2008
1O66
41.7%
Francisella tularensis
Biosynthesis of cofactors, prosthetic groups, and carriers
Pantothenate and coenzyme A
IDP90578
(
show subtarget assignments
)
8
expressed
No
YPO3401
16123550
panB
3-methyl-2-oxobutanoate hydroxymethyltra...
266
Predicted Essential
Community Requests
1M3U
75.9%
Yersinia pestis
IDP90802
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO3769
16123905
3-octaprenyl-4-hydroxybenzoate decarboxy...
498
Predicted Essential
Community Requests
2IDB
88.2%
Yersinia pestis
IDP00334
(
show subtarget assignments
)
1
in_pdb
3LYL
No
FTT1375
56708428
fabG
3-oxoacyl-(acyl-carrier-protein) reducta...
247
Drug Target Function
Phase 2: March 2008
3LYL
100%
Francisella tularensis
Fatty acid and phospholipid metabolism
Biosynthesis
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