|
|---|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Selection
Phase |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP00101
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
NT01SF2638 |
30041803 |
mrp |
putative ATPase |
369 |
Phase 1: October 2007 |
2PH1
|
27.1% |
Shigella flexneri |
Unknown function |
General |
|
|
|
IDP00204
(show subtarget assignments)
|
1 |
expressed |
No |
YPO1702 |
16121962 |
- |
putative membrane protein |
450 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00025
(show subtarget assignments)
|
1 |
purified |
No |
BA_0285 |
30253779 |
|
bacitracin ABC transporter, ATP-binding ... |
309 |
Phase 1: October 2007 |
1OXS
|
30.7% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00203
(show subtarget assignments)
|
1 |
in_pdb
3T7B |
No |
YPO3925 |
16124056 |
argB |
acetylglutamate kinase |
257 |
Phase 1: October 2007 |
3T7B
|
100% |
Yersinia pestis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP00100
(show subtarget assignments)
|
0 |
work_stopped |
No |
NT01SF2345 |
30041591 |
cheW |
positive regulator of CheA protein activ... |
167 |
Phase 1: October 2007 |
2HO9
|
100% |
Shigella flexneri |
Cellular processes |
Chemotaxis and motility |
|
|
|
IDP00050
(show subtarget assignments)
|
1 |
cloned |
No |
BA_3443 |
30257983 |
|
enhancin family protein |
742 |
Phase 1: October 2007 |
|
|
Bacillus anthracis |
Cellular processes |
Pathogenesis |
|
|
|
IDP00202
(show subtarget assignments)
|
1 |
soluble |
No |
YPO2731 |
16122935 |
- |
putative membrane protein |
679 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00201
(show subtarget assignments)
|
1 |
expressed |
No |
YPO1476 |
16121751 |
- |
hypothetical protein |
727 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Energy metabolism |
Photosynthesis |
|
|
|
IDP00099
(show subtarget assignments)
|
0 |
work_stopped |
No |
NT02SF1983 |
30041448 |
ynhD |
putative ATP-binding component of a tran... |
248 |
Phase 1: October 2007 |
2D3W
|
99.6% |
Shigella flexneri |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP00200
(show subtarget assignments)
|
1 |
expressed |
No |
YPO1473 |
16121748 |
- |
hypothetical protein |
766 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP00199
(show subtarget assignments)
|
1 |
purified |
No |
YPO1431 |
16121710 |
- |
putative Lon protease |
590 |
Phase 1: October 2007 |
3K1J
|
17.6% |
Yersinia pestis |
Protein synthesis |
Ribosomal proteins: synthesis and modification |
|
|
|
IDP00098
(show subtarget assignments)
|
1 |
soluble |
No |
NT01SF2011 |
30041408 |
slyA |
transcriptional regulator |
146 |
Phase 1: October 2007 |
3DEU
|
88.4% |
Shigella flexneri |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00049
(show subtarget assignments)
|
0 |
work_stopped |
No |
BA_3355 |
30257898 |
|
thiol-activated cytolysin |
512 |
Phase 1: October 2007 |
3CQF
|
93.6% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00198
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1367 |
16121647 |
- |
conserved hypothetical protein |
106 |
Phase 1: October 2007 |
1MBU
|
84.9% |
Yersinia pestis |
|
|
|
|
|
IDP00197
(show subtarget assignments)
|
1 |
purified |
No |
YPO1233 |
16121519 |
- |
putative prophage repressor protein |
240 |
Phase 1: October 2007 |
3BDN
|
46.2% |
Yersinia pestis |
|
|
|
|
|
IDP00097
(show subtarget assignments)
|
1 |
expressed |
No |
NTL02SF1117 |
30040935 |
S1242 |
hypothetical protein S1242 |
773 |
Phase 1: October 2007 |
3QQ2
|
9.8% |
Shigella flexneri |
Cellular processes |
Pathogenesis |
|
|
|
IDP00196
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1051 |
16121351 |
- |
putative membrane protein |
451 |
Phase 1: October 2007 |
2ZPL
|
13.5% |
Yersinia pestis |
|
|
|
|
|
IDP00024
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_0039 |
33516921 |
|
Dimethyladenosine transferase (S-adenosy... |
292 |
Phase 1: October 2007 |
3GRR
|
37.7% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00012
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_2953 |
61211623 |
|
3-phosphoshikimate 1-carboxyvinyltransfe... |
429 |
Phase 1: October 2007 |
3RMT
|
66.2% |
Bacillus anthracis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00195
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1009 |
16121311 |
- |
probable peptidase |
410 |
Phase 1: October 2007 |
1VIX
|
38% |
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00096
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
NTL02SF1070 |
30040886 |
ycfO |
hypothetical protein S1191 |
341 |
Phase 1: October 2007 |
1TR9
|
55.7% |
Shigella flexneri |
Energy metabolism |
Biosynthesis and degradation of polysaccharides |
|
|
|
IDP00048
(show subtarget assignments)
|
1 |
cloned |
No |
BA_3330 |
30257875 |
|
beta-lactam antibiotic acylase family pr... |
796 |
Phase 1: October 2007 |
1KEH
|
22.2% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00006
(show subtarget assignments)
|
1 |
soluble |
No |
BA_0672 |
30254271 |
|
immune inhibitor A metalloprotease |
799 |
Phase 1: October 2007 |
|
|
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00194
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0983 |
16121287 |
- |
putative membrane protein |
216 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00193
(show subtarget assignments)
|
1 |
expressed |
No |
YPO0966 |
16121269 |
- |
putative kinase |
765 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP00095
(show subtarget assignments)
|
1 |
purified |
No |
NT01SF1278 |
30040854 |
flgN |
flagella synthesis protein FlgN |
138 |
Phase 1: October 2007 |
|
|
Shigella flexneri |
Cell envelope |
Surface structures |
|
|
|
IDP00192
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0947 |
16121251 |
- |
putative virulence determinant |
3110 |
Phase 1: October 2007 |
1AF0
|
2.9% |
Yersinia pestis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00191
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0932 |
16121236 |
- |
conserved hypothetical protein |
170 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00094
(show subtarget assignments)
|
0 |
work_stopped |
No |
NT01SF0993 |
30040622 |
lrp |
regulator for leucine (or lrp) regulon a... |
164 |
Phase 1: October 2007 |
2GQQ
|
99.4% |
Shigella flexneri |
Central intermediary metabolism |
Other |
|
|
|
IDP00047
(show subtarget assignments)
|
1 |
in_pdb
3PP9 |
No |
BA_3185 |
30257752 |
|
streptothricin acetyltransferase, putati... |
184 |
Phase 1: October 2007 |
3PP9
|
100% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00190
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0927 |
16121232 |
- |
putative lipoprotein |
250 |
Phase 1: October 2007 |
3C37
|
23.6% |
Yersinia pestis |
Mobile and extrachromosomal element functions |
Transposon functions |
|
|
|
IDP00189
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO0845 |
16121153 |
- |
ThiJ/PfpI-family thiamine biogenesis pro... |
192 |
Phase 1: October 2007 |
1J42
|
29.2% |
Yersinia pestis |
Cellular processes |
Chemotaxis and motility |
|
|
|
IDP00093
(show subtarget assignments)
|
1 |
expressed |
No |
NT01SF0510 |
30040252 |
ybbF |
hypothetical protein S0463 |
240 |
Phase 1: October 2007 |
|
|
Shigella flexneri |
Unknown function |
General |
|
|
|
IDP00188
(show subtarget assignments)
|
1 |
purified |
No |
YPO0806 |
16121118 |
- |
prepilin peptidase |
280 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Cellular processes |
Chemotaxis and motility |
|
|
|
IDP00023
(show subtarget assignments)
|
1 |
cloned |
No |
BA_5594 |
30260051 |
papR |
PapR |
48 |
Phase 1: October 2007 |
|
|
Bacillus anthracis |
Cellular processes |
Pathogenesis |
|
|
|
IDP00187
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO0773 |
16121086 |
- |
putative thioesterase |
254 |
Phase 1: October 2007 |
3FLA
|
30.3% |
Yersinia pestis |
Regulatory functions |
Other |
|
|
|
IDP00092
(show subtarget assignments)
|
1 |
expressed |
No |
NT01SF0466 |
30040219 |
hemH |
ferrochelatase |
320 |
Phase 1: October 2007 |
1L8X
|
27.9% |
Shigella flexneri |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP00046
(show subtarget assignments)
|
1 |
in_pdb
3FOB |
Yes |
BA_3165 |
30257736 |
|
bromoperoxidase |
278 |
Phase 1: October 2007 |
3FOB
|
100% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00186
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0695 |
16121016 |
- |
putative membrane protein |
140 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP00185
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0639 |
16120963 |
- |
hypothetical protein |
460 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00091
(show subtarget assignments)
|
0 |
work_stopped |
No |
NTL01SF0342 |
30040153 |
ribD |
bifunctional pyrimidine deaminase/reduct... |
367 |
Phase 1: October 2007 |
2G6V
|
97.8% |
Shigella flexneri |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP00184
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0624 |
16120950 |
- |
putative membrane protein |
483 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00183
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0613 |
16120939 |
- |
putative permease protein |
293 |
Phase 1: October 2007 |
2R6G
|
22.5% |
Yersinia pestis |
|
|
|
|
|
IDP00090
(show subtarget assignments)
|
1 |
crystallized |
No |
NT01SF0319 |
30040101 |
crl |
transcriptional regulator of cryptic csg... |
133 |
Phase 1: October 2007 |
3RPJ
|
45.9% |
Shigella flexneri |
Cell envelope |
Surface structures |
|
|
|
IDP00045
(show subtarget assignments)
|
1 |
purified |
No |
BA_3111 |
30257692 |
|
aminoglycoside phosphotransferase family... |
292 |
Phase 1: October 2007 |
3LZH
|
17.8% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00182
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0398 |
16120732 |
- |
M48 peptidase family protein |
348 |
Phase 1: October 2007 |
3C37
|
10.1% |
Yersinia pestis |
Protein synthesis |
Translation factors |
|
|
|
IDP00181
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0363 |
16120698 |
- |
putative membrane transport protein |
1119 |
Phase 1: October 2007 |
2OAU
|
5% |
Yersinia pestis |
DNA metabolism |
DNA replication, recombination, and repair |
|
|
|
IDP00089
(show subtarget assignments)
|
0 |
work_stopped |
No |
NT01ST0526 |
16418927 |
dxs |
1-deoxyxylulose-5-phosphate synthase; fl... |
620 |
Phase 1: October 2007 |
2O1S
|
96.3% |
Salmonella enterica |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP00180
(show subtarget assignments)
|
1 |
expressed |
No |
YPO0339 |
16120675 |
- |
enhancing factor (viral) |
856 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Mobile and extrachromosomal element functions |
Transposon functions |
|
|
|
IDP00022
(show subtarget assignments)
|
1 |
cloned |
No |
BA_5578 |
81714842 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltr... |
429 |
Phase 1: October 2007 |
3SG1
|
49.7% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00011
(show subtarget assignments)
|
1 |
soluble |
No |
BA_2222 |
30256868 |
|
alcohol dehydrogenase, iron-containing |
392 |
Phase 1: October 2007 |
3OWO
|
37.8% |
Bacillus anthracis |
Energy metabolism |
Fermentation |
|
|
|
IDP00179
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0277 |
16120616 |
- |
putative transmembrane transport protein... |
428 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Unknown function |
General |
|
|
|
IDP00178
(show subtarget assignments)
|
1 |
soluble |
No |
YPO3405 |
16123554 |
- |
putative ABC transporter, integral membr... |
256 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00044
(show subtarget assignments)
|
1 |
in_pdb
3SLB
3SLF
3E4F
3IJW
3N0S
3KZL
3N0M |
Yes |
BA_2930 |
30257522 |
aacC7 |
aminoglycoside N3-acetyltransferase |
265 |
Phase 1: October 2007 |
3E4F
|
100% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00177
(show subtarget assignments)
|
1 |
purified |
No |
YPO3007 |
16123186 |
- |
putative membrane protein |
509 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00087
(show subtarget assignments)
|
1 |
expressed |
No |
NTL01ST2379 |
16420989 |
STM2449 |
putative acetyltransferase |
178 |
Phase 1: October 2007 |
2PDO
|
75.3% |
Salmonella enterica |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00176
(show subtarget assignments)
|
1 |
cloned |
No |
YPO4024 |
16124147 |
- |
putative iron transport permease |
335 |
Phase 1: October 2007 |
2QI9
|
23.9% |
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00175
(show subtarget assignments)
|
1 |
soluble |
No |
YPO1471 |
16121746 |
- |
putative ATPase subunit of ATP-dependent... |
880 |
Phase 1: October 2007 |
1QVR
|
36.9% |
Yersinia pestis |
|
|
|
|
|
IDP00086
(show subtarget assignments)
|
1 |
in_pdb
3DR6
3DR8 |
No |
NT01ST1973 |
16420114 |
yncA |
putative acyltransferase |
171 |
Phase 1: October 2007 |
3DR6
|
100% |
Salmonella enterica |
Transport and binding proteins |
Other |
|
|
|
IDP00043
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_2629 |
30257246 |
|
acetyltransferase, CYSE/LACA/LPXA/NODL f... |
210 |
Phase 1: October 2007 |
4E8L
|
63.3% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00174
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1140 |
16121437 |
- |
putative membrane protein |
272 |
Phase 1: October 2007 |
|
|
Yersinia pestis |
Unknown function |
General |
|
|
|
IDP00173
(show subtarget assignments)
|
1 |
cloned |
No |
YPO2922 |
16123109 |
- |
putative membrane protein |
486 |
Phase 1: October 2007 |
3K4U
|
14.4% |
Yersinia pestis |
Unknown function |
General |
|
|
|
IDP00085
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
NTL01ST1174 |
16419726 |
nagZ |
putative glycosyl hydrolase |
341 |
Phase 1: October 2007 |
1TR9
|
55.4% |
Salmonella enterica |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00172
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO2438 |
16122659 |
- |
putative membrane-bound lytic murein tra... |
220 |
Phase 1: October 2007 |
2Y8P
|
42.7% |
Yersinia pestis |
Mobile and extrachromosomal element functions |
Prophage functions |
|
|
|
IDP00021
(show subtarget assignments)
|
1 |
in_pdb
3SG1 |
No |
BA_5529 |
81714862 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltr... |
434 |
Phase 1: October 2007 |
3SG1
|
100% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00171
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0452 |
16120781 |
- |
putative soluble lytic murein transglyco... |
639 |
Phase 1: October 2007 |
1QSA
|
61.8% |
Yersinia pestis |
Hypothetical proteins |
Conserved |
|
|
|
IDP00084
(show subtarget assignments)
|
1 |
expressed |
No |
NT01ST1435 |
16419673 |
yceI |
putative secreted protein |
191 |
Phase 1: October 2007 |
1Y0G
|
91.1% |
Salmonella enterica |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00042
(show subtarget assignments)
|
1 |
soluble |
No |
BA_2507 |
30257134 |
bla1 |
beta-lactamase |
309 |
Phase 1: October 2007 |
3QHY
|
87.7% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00170
(show subtarget assignments)
|
1 |
soluble |
No |
VCA0865 |
15601620 |
hap |
hemagglutinin/protease |
609 |
Phase 1: October 2007 |
1EZM
|
31.4% |
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00169
(show subtarget assignments)
|
1 |
expressed |
No |
VCA0218 |
15600987 |
No Data |
thermolabile hemolysin |
418 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00083
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
NTL01ST0073 |
16418570 |
caiA |
putative acyl-CoA dehydrogenase, carniti... |
380 |
Phase 1: October 2007 |
2DVL
|
32.6% |
Salmonella enterica |
Fatty acid and phospholipid metabolism |
Degradation |
|
|
|
IDP00168
(show subtarget assignments)
|
1 |
cloned |
No |
VC2209 |
15642774 |
vibF |
nonribosomal peptide synthetase VibF, au... |
2413 |
Phase 1: October 2007 |
2VSQ
|
10.2% |
Vibrio cholerae |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00082
(show subtarget assignments)
|
0 |
work_stopped |
No |
NTL01ST4427 |
16423142 |
lplA |
lipoate-protein ligase A |
338 |
Phase 1: October 2007 |
1X2G
|
93.2% |
Salmonella enterica |
Cell envelope |
Other |
|
|
|
IDP00041
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_2409 |
30257040 |
|
chloramphenicol acetyltransferase |
216 |
Phase 1: October 2007 |
1QCA
|
41.2% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00166
(show subtarget assignments)
|
1 |
expressed |
No |
VC1450 |
15641461 |
rtxC |
RTX toxin activating protein |
153 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00165
(show subtarget assignments)
|
1 |
cloned |
No |
VC0844 |
15640861 |
acfA |
accessory colonization factor AcfA |
215 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00081
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
NT01ST5473 |
16422973 |
ytfP |
putative cytoplasmic protein |
114 |
Phase 1: October 2007 |
1XHS
|
92.1% |
Salmonella enterica |
Unknown function |
General |
|
|
|
IDP00164
(show subtarget assignments)
|
1 |
soluble |
No |
VC0841 |
15640858 |
acfC |
accessory colonization factor AcfC |
256 |
Phase 1: October 2007 |
3FIR
|
50% |
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00020
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_5315 |
47605857 |
|
UDP-N-acetylenolpyruvoylglucosamine redu... |
305 |
Phase 1: October 2007 |
1HSK
|
59.7% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00010
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_2144 |
30256791 |
|
uroporphyrin-III C-methyltransferase, pu... |
474 |
Phase 1: October 2007 |
1PJQ
|
24.1% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP00163
(show subtarget assignments)
|
0 |
work_stopped |
No |
VC0838 |
15640855 |
tcpN/toxT |
TCP pilus virulence regulatory protein |
276 |
Phase 1: October 2007 |
3GBG
|
100% |
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00080
(show subtarget assignments)
|
1 |
expressed |
No |
NT01ST5073 |
16422645 |
yneC |
putative inner membrane protein |
109 |
Phase 1: October 2007 |
3QMQ
|
70.6% |
Salmonella enterica |
Cell envelope |
Other |
|
|
|
IDP00040
(show subtarget assignments)
|
1 |
purified |
No |
BA_2042 |
46395770 |
|
Metallothiol transferase fosB 1 (Fosfomy... |
138 |
Phase 1: October 2007 |
3UH9
|
67.4% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00005
(show subtarget assignments)
|
1 |
cloned |
No |
BA_0552 |
30254078 |
|
internalin, putative |
1070 |
Phase 1: October 2007 |
1M9S
|
13.5% |
Bacillus anthracis |
Cellular processes |
Pathogenesis |
|
|
|
IDP00162
(show subtarget assignments)
|
1 |
soluble |
No |
VC0837 |
15640854 |
tcpF |
toxin co-regulated pilus biosynthesis pr... |
338 |
Phase 1: October 2007 |
3OC5
|
93.5% |
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00161
(show subtarget assignments)
|
1 |
soluble |
No |
VC0835 |
15640852 |
tcpT |
toxin co-regulated pilus biosynthesis pr... |
503 |
Phase 1: October 2007 |
1P9R
|
23.5% |
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00079
(show subtarget assignments)
|
1 |
in_pdb
3DSA
3E7N |
No |
NT01ST4845 |
16422456 |
rbsD |
D-ribose high-affinity transport system ... |
139 |
Phase 1: October 2007 |
3DSA
|
100% |
Salmonella enterica |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP00160
(show subtarget assignments)
|
1 |
soluble |
No |
VC0834 |
15640851 |
tcpS |
toxin co-regulated pilus biosynthesis pr... |
152 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00159
(show subtarget assignments)
|
1 |
purified |
No |
VC0831 |
15640848 |
tcpC |
toxin co-regulated pilus biosynthesis ou... |
489 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00078
(show subtarget assignments)
|
0 |
work_stopped |
No |
NTL01ST3606 |
16422278 |
rfaF |
ADP-heptose; LPS heptosyltransferase 1 |
348 |
Phase 1: October 2007 |
1PSW
|
91.7% |
Salmonella enterica |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00039
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_1960 |
30256617 |
|
aminoglycoside 6-adenylyltransferase, pu... |
290 |
Phase 1: October 2007 |
2PBE
|
37.9% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00158
(show subtarget assignments)
|
1 |
soluble |
No |
VC0830 |
15640847 |
tcpQ |
toxin co-regulated pilus biosynthesis pr... |
150 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00157
(show subtarget assignments)
|
1 |
soluble |
No |
VC0829 |
15640846 |
tcpB |
toxin co-regulated pilus biosynthesis pr... |
430 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00077
(show subtarget assignments)
|
0 |
work_stopped |
No |
NTL01ST3489 |
16422154 |
yhiQ |
putative SAM-dependent methyltransferase... |
252 |
Phase 1: October 2007 |
2PKW
|
100% |
Salmonella enterica |
Central intermediary metabolism |
Other |
|
|
|
IDP00156
(show subtarget assignments)
|
1 |
purified |
No |
VC0407 |
15640434 |
mshF |
MSHA biogenesis protein MshF |
150 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00019
(show subtarget assignments)
|
1 |
cloned |
No |
BA_4843 |
30259344 |
pykA-2 |
pyruvate kinase |
585 |
Phase 1: October 2007 |
2E28
|
69.6% |
Bacillus anthracis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP00155
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
VC0405 |
15640432 |
mshE |
MSHA biogenesis protein MshE |
575 |
Phase 1: October 2007 |
1P9R
|
31.7% |
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00076
(show subtarget assignments)
|
1 |
in_pdb
3NX4 |
No |
NT01ST4228 |
16421936 |
yhdH |
putative oxidoreductase |
324 |
Phase 1: October 2007 |
3NX4
|
100% |
Salmonella enterica |
Cellular processes |
Cell division |
|
|
|
IDP00038
(show subtarget assignments)
|
1 |
in_pdb
3SR3
3GJZ
3T5M
3TYX
3U1B |
No |
BA_1949 |
30256607 |
|
microcin immunity protein MccF |
333 |
Phase 1: October 2007 |
3GJZ
|
100% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00154
(show subtarget assignments)
|
1 |
crystallized |
No |
VC2448 |
15642444 |
pyrG |
CTP synthase |
545 |
Phase 1: October 2007 |
1S1M
|
79.5% |
Vibrio cholerae |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
